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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:propafenone
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Accession:CHEBI:63619 term browser browse the term
Definition:An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.
Synonyms:exact_synonym: 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one
 related_synonym: 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone;   2-(2'-hydroxy-3'-propylaminopropoxy)-omega-phenylpropiophenone;   Formula=C21H27NO3;   InChI=1S/C21H27NO3/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17/h3-11,18,22-23H,2,12-16H2,1H3;   InChIKey=JWHAUXFOSRPERK-UHFFFAOYSA-N;   SMILES=CCCNCC(O)COc1ccccc1C(=O)CCc1ccccc1;   propafenona;   propafenonum
 alt_id: CHEBI:8465
 xref: CAS:54063-53-5;   DrugBank:DB01182;   Drug_Central:2291;   KEGG:C07381;   KEGG:D08435;   LINCS:LSM-1416
 xref_mesh: MESH:D011405
 xref: PMID:8777484;   Patent:DE2001431;   Reaxys:2175182;   Wikipedia:Propafenone
 cyclic_relationship: is_conjugate_base_of CHEBI:63650

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  CHEBI ontology 0
    role 0
      application 0
        pharmaceutical 0
          drug 0
            cardiovascular drug 0
              anti-arrhythmia drug 0
                propafenone 0
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  CHEBI ontology 0
    subatomic particle 0
      composite particle 0
        hadron 0
          baryon 0
            nucleon 0
              atomic nucleus 0
                atom 0
                  main group element atom 0
                    main group molecular entity 0
                      s-block molecular entity 0
                        hydrogen molecular entity 0
                          hydrides 0
                            inorganic hydride 0
                              pnictogen hydride 0
                                nitrogen hydride 0
                                  azane 0
                                    ammonia 0
                                      organic amino compound 0
                                        secondary amino compound 0
                                          propafenone 0
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