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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:nelarabine
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Accession:CHEBI:63612 term browser browse the term
Definition:A purine nucleoside in which O-methylguanine is attached to arabinofuranose via a beta-N(9)-glycosidic bond. Inhibits DNA synthesis and causes cell death; a prodrug of 9-beta-D-arabinofuranosylguanine (ara-G).
Synonyms:exact_synonym: 9-(beta-D-arabinofuranosyl)-6-methoxy-9H-purin-2-amine
 related_synonym: 2-Amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purine;   Arranon;   Formula=C11H15N5O5;   InChI=1S/C11H15N5O5/c1-20-9-5-8(14-11(12)15-9)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14,15)/t4-,6-,7+,10-/m1/s1;   InChIKey=IXOXBSCIXZEQEQ-UHTZMRCNSA-N;   SMILES=COc1nc(N)nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O;   nelzarabine
 xref: CAS:121032-29-9;   DrugBank:DB01280;   Drug_Central:1892;   KEGG:D05134;   KEGG:D06488;   PMID:18586926;   PMID:19825456;   PMID:20043113;   PMID:20528871;   PMID:20616909;   PMID:20796200;   PMID:21151585;   PMID:21190039;   PMID:21320002;   PMID:21353591;   PMID:21715318;   PMID:21730354;   PMID:21737993;   PMID:22184539;   PMID:63612;   Reaxys:13568768



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Term Annotations click to browse term
  CHEBI ontology 19860
    role 19832
      application 19675
        pro-agent 11550
          prodrug 11310
            nelarabine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19860
    subatomic particle 19858
      composite particle 19858
        hadron 19858
          baryon 19858
            nucleon 19858
              atomic nucleus 19858
                atom 19858
                  main group element atom 19804
                    p-block element atom 19804
                      carbon group element atom 19745
                        carbon atom 19741
                          organic molecular entity 19741
                            heteroorganic entity 19494
                              organochalcogen compound 19257
                                organooxygen compound 19173
                                  carbohydrates and carbohydrate derivatives 15291
                                    carbohydrate 15291
                                      carbohydrate derivative 14299
                                        glycosyl compound 13053
                                          glycoside 11832
                                            pentoside 587
                                              arabinoside 585
                                                beta-D-arabinoside 584
                                                  9-beta-D-arabinofuranosylguanine 0
                                                    nelarabine 0
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