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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:63578 term browser browse the term
Definition:A dicarboxylic acid diamide that consists of N-methylisophthalamide bearing three iodo substituents at positions 2, 4 and 6, a methoxyacetyl substituent at position 5 and two 2,3-dihydroxypropyl groups attached to the amide nitrogens. A water soluble x-ray contrast agent for intravascular administration.
Synonyms:exact_synonym: N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methylisophthalamide
 related_synonym: Formula=C18H24I3N3O8;   InChI=1S/C18H24I3N3O8/c1-24(4-9(28)6-26)18(31)12-13(19)11(17(30)22-3-8(27)5-25)14(20)16(15(12)21)23-10(29)7-32-2/h8-9,25-28H,3-7H2,1-2H3,(H,22,30)(H,23,29);   InChIKey=DGAIEPBNLOQYER-UHFFFAOYSA-N;   N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyacetamido)-N-methylisophthalamide;   SMILES=COCC(=O)Nc1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)N(C)CC(O)CO)c1I;   Ultravist;   iopromida;   iopromidum
 alt_id: CHEBI:31712
 xref: Beilstein:7085608;   CAS:73334-07-3;   Drug_Central:1468;   HMDB:HMDB0041910;   KEGG:D01893;   LINCS:LSM-5134
 xref_mesh: MESH:C038192
 xref: PMID:20412314;   PMID:20890877;   PMID:20921088;   PMID:21039317;   PMID:21141818;   PMID:21159465;   PMID:21529272;   PMID:21545991;   PMID:21623210;   PMID:21877755;   PMID:21943940;   PMID:22028567;   PMID:22178894;   Patent:DE2909439;   Patent:US4364921;   Reaxys:7085608;   Wikipedia:Iopromide

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iopromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 increases expression EXP iopromide results in increased expression of EDN1 protein CTD PMID:21354280 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Mr1 major histocompatibility complex, class I-related affects expression ISO iopromide affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr13:72,771,992...72,789,861
Ensembl chr13:72,771,984...72,789,841
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression EXP iopromide results in decreased expression of NOS2 protein CTD PMID:21354280 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G RT1-Da RT1 class II, locus Da affects expression ISO iopromide affects the expression of HLA-DRA mRNA CTD PMID:25811541 NCBI chr20:4,127,644...4,132,616
Ensembl chr20:4,127,644...4,132,616
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19786
    role 19732
      biological role 19732
        xenobiotic 18425
          iopromide 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19786
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19675
                    p-block element atom 19675
                      carbon group element atom 19596
                        carbon atom 19586
                          organic molecular entity 19586
                            organic group 18631
                              organic divalent group 18622
                                organodiyl group 18622
                                  carbonyl group 18537
                                    carbonyl compound 18537
                                      carboxylic acid 18215
                                        carboacyl group 17441
                                          univalent carboacyl group 17441
                                            carbamoyl group 17248
                                              carboxamide 17248
                                                dicarboxylic acid amide 3135
                                                  dicarboxylic acid diamide 2684
                                                    benzenedicarboxamide 50
                                                      isophthalamide 4
                                                        iopromide 4
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