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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:iopromide
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Accession:CHEBI:63578 term browser browse the term
Definition:A dicarboxylic acid diamide that consists of N-methylisophthalamide bearing three iodo substituents at positions 2, 4 and 6, a methoxyacetyl substituent at position 5 and two 2,3-dihydroxypropyl groups attached to the amide nitrogens. A water soluble x-ray contrast agent for intravascular administration.
Synonyms:exact_synonym: N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methylisophthalamide
 related_synonym: Formula=C18H24I3N3O8;   InChI=1S/C18H24I3N3O8/c1-24(4-9(28)6-26)18(31)12-13(19)11(17(30)22-3-8(27)5-25)14(20)16(15(12)21)23-10(29)7-32-2/h8-9,25-28H,3-7H2,1-2H3,(H,22,30)(H,23,29);   InChIKey=DGAIEPBNLOQYER-UHFFFAOYSA-N;   N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyacetamido)-N-methylisophthalamide;   SMILES=COCC(=O)Nc1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)N(C)CC(O)CO)c1I;   Ultravist;   iopromida;   iopromidum
 alt_id: CHEBI:31712
 xref: Beilstein:7085608;   CAS:73334-07-3;   Drug_Central:1468;   HMDB:HMDB0041910;   KEGG:D01893;   LINCS:LSM-5134
 xref_mesh: MESH:C038192
 xref: PMID:20412314;   PMID:20890877;   PMID:20921088;   PMID:21039317;   PMID:21141818;   PMID:21159465;   PMID:21529272;   PMID:21545991;   PMID:21623210;   PMID:21877755;   PMID:21943940;   PMID:22028567;   PMID:22178894;   Patent:DE2909439;   Patent:US4364921;   Reaxys:7085608;   Wikipedia:Iopromide


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iopromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 increases expression EXP iopromide results in increased expression of EDN1 protein CTD PMID:21354280 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Mr1 major histocompatibility complex, class I-related affects expression ISO iopromide affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr13:72,771,992...72,789,861
Ensembl chr13:72,771,984...72,789,841
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression EXP iopromide results in decreased expression of NOS2 protein CTD PMID:21354280 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G RT1-Da RT1 class II, locus Da affects expression ISO iopromide affects the expression of HLA-DRA mRNA CTD PMID:25811541 NCBI chr20:4,127,644...4,132,616
Ensembl chr20:4,127,644...4,132,616
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19781
    role 19726
      biological role 19726
        xenobiotic 18398
          iopromide 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19781
    subatomic particle 19779
      composite particle 19779
        hadron 19779
          baryon 19779
            nucleon 19779
              atomic nucleus 19779
                atom 19779
                  main group element atom 19669
                    p-block element atom 19669
                      carbon group element atom 19588
                        carbon atom 19578
                          organic molecular entity 19578
                            organic group 18620
                              organic divalent group 18611
                                organodiyl group 18611
                                  carbonyl group 18526
                                    carbonyl compound 18526
                                      carboxylic acid 18202
                                        carboacyl group 17418
                                          univalent carboacyl group 17418
                                            carbamoyl group 17216
                                              carboxamide 17216
                                                dicarboxylic acid amide 3131
                                                  dicarboxylic acid diamide 2680
                                                    benzenedicarboxamide 50
                                                      isophthalamide 4
                                                        iopromide 4
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