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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:63578 term browser browse the term
Definition:A dicarboxylic acid diamide that consists of N-methylisophthalamide bearing three iodo substituents at positions 2, 4 and 6, a methoxyacetyl substituent at position 5 and two 2,3-dihydroxypropyl groups attached to the amide nitrogens. A water soluble x-ray contrast agent for intravascular administration.
Synonyms:exact_synonym: N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methylisophthalamide
 related_synonym: Formula=C18H24I3N3O8;   InChI=1S/C18H24I3N3O8/c1-24(4-9(28)6-26)18(31)12-13(19)11(17(30)22-3-8(27)5-25)14(20)16(15(12)21)23-10(29)7-32-2/h8-9,25-28H,3-7H2,1-2H3,(H,22,30)(H,23,29);   InChIKey=DGAIEPBNLOQYER-UHFFFAOYSA-N;   N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyacetamido)-N-methylisophthalamide;   SMILES=COCC(=O)Nc1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)N(C)CC(O)CO)c1I;   Ultravist;   iopromida;   iopromidum
 alt_id: CHEBI:31712
 xref: Beilstein:7085608;   CAS:73334-07-3;   Drug_Central:1468;   HMDB:HMDB0041910;   KEGG:D01893;   LINCS:LSM-5134
 xref_mesh: MESH:C038192
 xref: PMID:20412314;   PMID:20890877;   PMID:20921088;   PMID:21039317;   PMID:21141818;   PMID:21159465;   PMID:21529272;   PMID:21545991;   PMID:21623210;   PMID:21877755;   PMID:21943940;   PMID:22028567;   PMID:22178894;   Patent:DE2909439;   Patent:US4364921;   Reaxys:7085608;   Wikipedia:Iopromide

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iopromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 increases expression EXP iopromide results in increased expression of EDN1 protein CTD PMID:21354280 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Mr1 major histocompatibility complex, class I-related affects expression ISO iopromide affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression EXP iopromide results in decreased expression of NOS2 protein CTD PMID:21354280 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G RT1-Da RT1 class II, locus Da affects expression ISO iopromide affects the expression of HLA-DRA mRNA CTD PMID:25811541 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      biological role 20011
        xenobiotic 18699
          iopromide 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic group 18988
                              organic divalent group 18950
                                organodiyl group 18974
                                  carbonyl group 18903
                                    carbonyl compound 18925
                                      carboxylic acid 18597
                                        carboacyl group 17730
                                          univalent carboacyl group 17710
                                            carbamoyl group 17550
                                              carboxamide 17570
                                                dicarboxylic acid amide 3148
                                                  dicarboxylic acid diamide 2695
                                                    benzenedicarboxamide 61
                                                      isophthalamide 4
                                                        iopromide 4
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