Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1-phenyl-1,2-propanedione
go back to main search page
Accession:CHEBI:63552 term browser browse the term
Definition:An alpha-diketone that consists of 1-phenylpropane bearing keto substituents at positions 1 and 2. It is found in coffee.
Synonyms:exact_synonym: 1-phenylpropane-1,2-dione
 related_synonym: 1-phenyl-1,2-dioxopropane;   3-Phenyl-2,3-propanedione;   Acetyl benzoyl;   Acetylbenzoyl;   Benzoyl methyl ketone;   Benzoylacetyl;   Formula=C9H8O2;   InChI=1S/C9H8O2/c1-7(10)9(11)8-5-3-2-4-6-8/h2-6H,1H3;   InChIKey=BVQVLAIMHVDZEL-UHFFFAOYSA-N;   Methyl phenyl glyoxal;   Methylphenylglyoxal;   Phenyl methyl diketone;   Phenylmethyldiketone;   Pyruvophenone;   SMILES=CC(=O)C(=O)c1ccccc1
 xref: CAS:579-07-7;   HMDB:HMDB0035243;   KEGG:C17268
 xref_mesh: MESH:C100349
 xref: MetaCyc:CPD-9949;   PMID:11796169;   Reaxys:878450



show annotations for term's descendants           Sort by:
 
1-phenyl-1,2-propanedione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b8 aldo-keto reductase family 1, member B8 multiple interactions EXP [AKR1B8 protein co-treated with NADP] affects the reduction of 1-phenyl-1,2-propanedione CTD PMID:18845131 NCBI chr 4:62,997,241...63,009,815
Ensembl chr 4:62,997,161...63,010,097
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO 1-phenyl-1,2-propanedione results in increased expression of AKR1C2 mRNA CTD PMID:20491607 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO 1-phenyl-1,2-propanedione results in increased expression of CYP1A1 mRNA CTD PMID:20491607 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Dhrs11 dehydrogenase/reductase 11 increases reduction ISO DHRS11 protein results in increased reduction of 1-phenyl-1,2-propanedione CTD PMID:30926317 NCBI chr10:69,698,214...69,708,294
Ensembl chr10:69,698,214...69,708,295
JBrowse link
G Dhrs2 dehydrogenase/reductase 2 multiple interactions ISO [NADP co-treated with DHRS2 protein] affects the metabolism of 1-phenyl-1,2-propanedione CTD PMID:16685466 NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO 1-phenyl-1,2-propanedione results in increased expression of HMOX1 mRNA CTD PMID:20491607 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO 1-phenyl-1,2-propanedione results in increased expression of MAFF mRNA CTD PMID:20491607 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      chemical role 19589
        environmental contaminant 18862
          benzene 5706
            alkylbenzene 3407
              propylbenzene 10
                1-phenyl-1,2-propanedione 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    main group molecular entity 19960
                      s-block molecular entity 19784
                        hydrogen molecular entity 19777
                          hydrides 19115
                            organic hydride 18675
                              organic fundamental parent 18657
                                hydrocarbon 18408
                                  cyclic hydrocarbon 17206
                                    monocyclic hydrocarbon 6061
                                      annulene 5708
                                        aromatic annulene 5706
                                          benzene 5706
                                            alkylbenzene 3407
                                              propylbenzene 10
                                                1-phenyl-1,2-propanedione 7
paths to the root