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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:8-azaguanine
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Accession:CHEBI:63486 term browser browse the term
Definition:A triazolopyrimidine that consists of 3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidine bearing amino and oxo substituents at positions 5 and 7 respectively.
Synonyms:exact_synonym: 5-amino-3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
 related_synonym: 3-amino-2,4,7,8,9-pentazabicyclo[4.3.0]nona-1,3,6-trien-5-one;   5-Amino-1,4-dihydro-7H-1,2,3-triazolo(4,5-d)pyrimidin-7-one;   5-Amino-1,6-dihydro-7H-v-triazolo(4,5-d)pyrimidin-7-one;   5-Amino-1H-v-triazolo(d)pyrimidin-7-ol;   5-Amino-7-hydroxy-1H-v-triazolo(d)pyrimidine;   5-amino-1H-triazolo[4,5-d]pyrimidin-7-ol;   8 AG;   AZG;   Azaguanine;   Formula=C4H4N6O;   Guanazol;   Guanazolo;   InChI=1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11);   InChIKey=LPXQRXLUHJKZIE-UHFFFAOYSA-N;   Pathocidin;   Pathocidine;   SMILES=Nc1nc2[nH]nnc2c(=O)[nH]1
 alt_id: CHEBI:40862
 xref: CAS:134-58-7;   DrugBank:DB01667;   LINCS:LSM-6615
 xref_mesh: MESH:D001375
 xref: MetaCyc:CPD0-1143;   PDBeChem:AZG;   PMID:22043012;   Reaxys:610785;   Wikipedia:Azaguanine



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8-azaguanine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapt microtubule-associated protein tau decreases expression ISO Azaguanine results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
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Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        biochemical role 19368
          antimetabolite 8546
            8-azaguanine 1
              8-aza-cAMP 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic molecule 19549
                              organic cyclic compound 19343
                                organic heterocyclic compound 18584
                                  organic heteropolycyclic compound 18043
                                    organic heterobicyclic compound 16859
                                      triazolopyrimidines 20
                                        8-azaguanine 1
                                          8-aza-cAMP 0
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