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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:8-azaguanine
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Accession:CHEBI:63486 term browser browse the term
Definition:A triazolopyrimidine that consists of 3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidine bearing amino and oxo substituents at positions 5 and 7 respectively.
Synonyms:exact_synonym: 5-amino-3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
 related_synonym: 3-amino-2,4,7,8,9-pentazabicyclo[4.3.0]nona-1,3,6-trien-5-one;   5-Amino-1,4-dihydro-7H-1,2,3-triazolo(4,5-d)pyrimidin-7-one;   5-Amino-1,6-dihydro-7H-v-triazolo(4,5-d)pyrimidin-7-one;   5-Amino-1H-v-triazolo(d)pyrimidin-7-ol;   5-Amino-7-hydroxy-1H-v-triazolo(d)pyrimidine;   5-amino-1H-triazolo[4,5-d]pyrimidin-7-ol;   8 AG;   AZG;   Azaguanine;   Formula=C4H4N6O;   Guanazol;   Guanazolo;   InChI=1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11);   InChIKey=LPXQRXLUHJKZIE-UHFFFAOYSA-N;   Pathocidin;   Pathocidine;   SMILES=Nc1nc2[nH]nnc2c(=O)[nH]1
 alt_id: CHEBI:40862
 xref: CAS:134-58-7;   DrugBank:DB01667;   LINCS:LSM-6615
 xref_mesh: MESH:D001375
 xref: MetaCyc:CPD0-1143;   PDBeChem:AZG;   PMID:22043012;   Reaxys:610785;   Wikipedia:Azaguanine


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8-azaguanine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapt microtubule-associated protein tau decreases expression ISO Azaguanine results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
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  CHEBI ontology 19818
    role 19790
      biological role 19788
        biochemical role 19501
          antimetabolite 8575
            8-azaguanine 1
              8-aza-cAMP 0
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Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            organic molecule 19656
                              organic cyclic compound 19461
                                organic heterocyclic compound 18817
                                  organic heteropolycyclic compound 18297
                                    organic heterobicyclic compound 17247
                                      triazolopyrimidines 20
                                        8-azaguanine 1
                                          8-aza-cAMP 0
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