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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:8-azaguanine
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Accession:CHEBI:63486 term browser browse the term
Definition:A triazolopyrimidine that consists of 3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidine bearing amino and oxo substituents at positions 5 and 7 respectively.
Synonyms:exact_synonym: 5-amino-3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
 related_synonym: 3-amino-2,4,7,8,9-pentazabicyclo[4.3.0]nona-1,3,6-trien-5-one;   5-Amino-1,4-dihydro-7H-1,2,3-triazolo(4,5-d)pyrimidin-7-one;   5-Amino-1,6-dihydro-7H-v-triazolo(4,5-d)pyrimidin-7-one;   5-Amino-1H-v-triazolo(d)pyrimidin-7-ol;   5-Amino-7-hydroxy-1H-v-triazolo(d)pyrimidine;   5-amino-1H-triazolo[4,5-d]pyrimidin-7-ol;   8 AG;   AZG;   Azaguanine;   Formula=C4H4N6O;   Guanazol;   Guanazolo;   InChI=1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11);   InChIKey=LPXQRXLUHJKZIE-UHFFFAOYSA-N;   Pathocidin;   Pathocidine;   SMILES=Nc1nc2[nH]nnc2c(=O)[nH]1
 alt_id: CHEBI:40862
 xref: CAS:134-58-7;   DrugBank:DB01667;   LINCS:LSM-6615
 xref_mesh: MESH:D001375
 xref: MetaCyc:CPD0-1143;   PDBeChem:AZG;   PMID:22043012;   Reaxys:610785;   Wikipedia:Azaguanine


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8-azaguanine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapt microtubule-associated protein tau decreases expression ISO Azaguanine results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
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  CHEBI ontology 19840
    role 19790
      biological role 19790
        biochemical role 19328
          antimetabolite 8497
            8-azaguanine 1
              8-aza-cAMP 0
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  CHEBI ontology 19840
    subatomic particle 19838
      composite particle 19838
        hadron 19838
          baryon 19838
            nucleon 19838
              atomic nucleus 19838
                atom 19838
                  main group element atom 19730
                    p-block element atom 19730
                      carbon group element atom 19635
                        carbon atom 19624
                          organic molecular entity 19624
                            organic molecule 19555
                              organic cyclic compound 19364
                                organic heterocyclic compound 18482
                                  organic heteropolycyclic compound 17872
                                    organic heterobicyclic compound 16804
                                      triazolopyrimidines 20
                                        8-azaguanine 1
                                          8-aza-cAMP 0
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