CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: glucitol derivative
Accession: CHEBI:63433
browse the term
Definition: A hexitol derivative that is formally obtained from a glucitol.
Synonyms: related_synonym: glucitol derivatives
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
decreases activity
ISO
Isosorbide Dinitrate results in decreased activity of CYP1A1 protein
CTD
PMID:33814510
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
G
Edn1
endothelin 1
multiple interactions
ISO
[Isosorbide Dinitrate co-treated with Plant Preparations] results in decreased expression of EDN1 mRNA
CTD
PMID:15719745
NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
G
G6pd
glucose-6-phosphate dehydrogenase
decreases response to substance
ISO
G6PD protein results in decreased susceptibility to Isosorbide Dinitrate
CTD
PMID:6401899
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
G
Nos3
nitric oxide synthase 3
multiple interactions
ISO
[Isosorbide Dinitrate co-treated with Ascorbic Acid] affects the expression of NOS3 mRNA; [Isosorbide Dinitrate co-treated with Plant Preparations] results in increased expression of NOS3 mRNA
CTD
PMID:15719745
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
G
Pafah1b1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1
multiple interactions
EXP
isosorbide-5-mononitrate inhibits the reaction [Castor Oil results in increased expression of PAFAH1B1 protein]
CTD
PMID:8738301
NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
CHEBI ontology
19918
role
19894
biological role
19892
biochemical role
19588
metabolite
19574
eukaryotic metabolite
19387
plant metabolite
17985
glucitol
46
glucitol derivative
5
D-glucuronic acid gamma-lactone
0
isosorbide dinitrate
4
isosorbide mononitrate
1
nitric acid [(3S,3aR,6R,6aS)-3-nitrooxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] ester
0
Path 2
CHEBI ontology
19918
subatomic particle
19916
composite particle
19916
hadron
19916
baryon
19916
nucleon
19916
atomic nucleus
19916
atom
19916
main group element atom
19866
p-block element atom
19866
carbon group element atom
19811
carbon atom
19806
organic molecular entity
19806
heteroorganic entity
19548
organochalcogen compound
19303
organooxygen compound
19217
carbohydrates and carbohydrate derivatives
15307
carbohydrate
15307
alditol
3302
hexitol
134
glucitol
46
glucitol derivative
5
D-glucuronic acid gamma-lactone
0
isosorbide dinitrate
4
isosorbide mononitrate
1
nitric acid [(3S,3aR,6R,6aS)-3-nitrooxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] ester
0