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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:barium chloride
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Accession:CHEBI:63317 term browser browse the term
Definition:The inorganic dichloride salt of barium.
Synonyms:exact_synonym: barium dichloride
 related_synonym: BaCl2;   Formula=BaCl2;   InChI=1S/Ba.2ClH/h;2*1H/q+2;;/p-2;   InChIKey=WDIHJSXYQDMJHN-UHFFFAOYSA-L;   SMILES=[Cl-].[Cl-].[Ba++]
 xref: CAS:10361-37-2
 xref_mesh: MESH:C024986
 xref: MetaCyc:CPD0-1592;   PMID:21601246;   Reaxys:1209229;   Reaxys:8128158;   Wikipedia:Barium_chloride


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barium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions ISO [barium chloride results in increased abundance of Barium] which results in decreased activity of ACHE protein CTD PMID:31407482 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728 		JBrowse link
G Alb albumin multiple interactions
increases secretion		 ISO Plant Extracts inhibits the reaction [barium chloride results in increased secretion of ALB protein] CTD PMID:26732703 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Cat catalase multiple interactions
decreases activity		 ISO [[Sodium Selenite results in increased abundance of Selenium] which co-treated with Ascorbic Acid] inhibits the reaction [barium chloride results in decreased activity of CAT protein]; [barium chloride results in increased abundance of Barium] which results in decreased activity of CAT protein; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [barium chloride results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [barium chloride results in decreased activity of CAT protein]; Plant Extracts inhibits the reaction [barium chloride results in decreased activity of CAT protein] CTD PMID:26732703 PMID:27941167 PMID:28683652 PMID:31407482 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G F3 coagulation factor III multiple interactions ISO barium chloride inhibits the reaction [TNF protein results in increased expression of F3 mRNA]; barium chloride inhibits the reaction [TNF protein results in increased expression of F3 protein] CTD PMID:23305835 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases activity ISO barium chloride results in increased activity of GGT1 protein CTD PMID:28683652 NCBI chr10:75,396,910...75,422,027
Ensembl chr10:75,397,438...75,422,034 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble increases activity ISO barium chloride results in increased activity of GOT1 protein CTD PMID:28683652 NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044 		JBrowse link
G Gpt glutamic pyruvic transaminase, soluble increases activity ISO barium chloride results in increased activity of GPT protein CTD PMID:28683652 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases activity ISO barium chloride results in decreased activity of GPX1 protein CTD PMID:28683652 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions		 ISO barium chloride results in increased expression of IL1B mRNA
Plant Extracts inhibits the reaction [barium chloride results in increased expression of IL1B mRNA]		 CTD PMID:26732703 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions		 ISO barium chloride results in increased expression of IL6 mRNA
[barium chloride results in increased abundance of Barium] which results in increased expression of IL6 protein; Plant Extracts inhibits the reaction [barium chloride results in increased expression of IL6 mRNA]		 CTD PMID:26732703 PMID:31407482 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 multiple interactions ISO barium chloride results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr16:92,142,889...92,156,356
Ensembl chr16:92,142,870...92,156,356 		JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 multiple interactions ISO barium chloride inhibits the reaction [KCNJ2 protein results in increased transport of Potassium] CTD PMID:11087224 NCBI chr11:110,956,990...110,967,651
Ensembl chr11:110,956,990...110,967,647 		JBrowse link
G Kcnk3 potassium channel, subfamily K, member 3 decreases activity ISO barium chloride results in decreased activity of KCNK3 protein CTD PMID:16020457 NCBI chr 5:30,745,514...30,782,614
Ensembl chr 5:30,745,514...30,782,615 		JBrowse link
G Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 multiple interactions ISO barium chloride results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr 7:142,660,614...142,980,787
Ensembl chr 7:142,660,099...142,980,779 		JBrowse link
G Ldha lactate dehydrogenase A increases activity ISO barium chloride results in increased activity of LDHA protein CTD PMID:28683652 NCBI chr 7:46,491,698...46,505,051
Ensembl chr 7:46,490,899...46,505,051 		JBrowse link
G Mt2 metallothionein 2 increases expression
multiple interactions		 ISO barium chloride results in increased expression of MT2A mRNA
Plant Extracts inhibits the reaction [barium chloride results in increased expression of MT2A mRNA]		 CTD PMID:26732703 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 increases secretion ISO barium chloride results in increased secretion of SERPINE1 protein CTD PMID:21596853 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial decreases expression
multiple interactions		 ISO barium chloride results in decreased expression of SOD2 mRNA
Plant Extracts inhibits the reaction [barium chloride results in decreased expression of SOD2 mRNA]		 CTD PMID:26732703 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Stx1a syntaxin 1A (brain) affects localization
multiple interactions		 ISO barium chloride affects the localization of STX1A protein
Propofol inhibits the reaction [barium chloride affects the localization of STX1A protein]; STX1A protein modified form inhibits the reaction [Propofol inhibits the reaction [barium chloride affects the localization of STX1A protein]]		 CTD PMID:29320738 NCBI chr 5:135,051,473...135,079,954
Ensembl chr 5:135,052,336...135,079,954 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 ISO Plant Extracts inhibits the reaction [barium chloride results in increased expression of TNF mRNA]
barium chloride inhibits the reaction [TNF protein results in increased expression of F3 mRNA]; barium chloride inhibits the reaction [TNF protein results in increased expression of F3 protein]		 CTD PMID:23305835 PMID:26732703 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions EXP [barium chloride results in increased abundance of Barium] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:139,440,277...139,501,257
Ensembl chr  X:139,440,277...139,501,408 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    chemical entity 22208
      molecular entity 22169
        inorganic molecular entity 21908
          inorganic salt 15112
            inorganic chloride 8057
              barium chloride 21
                barium chloride dihydrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    p-block element atom 22104
                      halogen 20279
                        chlorine atom 19728
                          chlorine molecular entity 19758
                            elemental chlorine 8343
                              monoatomic chlorine 8326
                                chloride 8326
                                  chloride salt 8336
                                    inorganic chloride 8057
                                      barium chloride 21
                                        barium chloride dihydrate 0
paths to the root