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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:barium chloride
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Accession:CHEBI:63317 term browser browse the term
Definition:The inorganic dichloride salt of barium.
Synonyms:exact_synonym: barium dichloride
 related_synonym: BaCl2;   Formula=BaCl2;   InChI=1S/Ba.2ClH/h;2*1H/q+2;;/p-2;   InChIKey=WDIHJSXYQDMJHN-UHFFFAOYSA-L;   SMILES=[Cl-].[Cl-].[Ba++]
 xref: CAS:10361-37-2
 xref_mesh: MESH:C024986
 xref: MetaCyc:CPD0-1592;   PMID:21601246;   Reaxys:1209229;   Reaxys:8128158;   Wikipedia:Barium_chloride


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barium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions EXP [barium chloride results in increased abundance of Barium] which results in decreased activity of ACHE protein CTD PMID:31407482 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Alb albumin multiple interactions
increases secretion		 EXP Plant Extracts inhibits the reaction [barium chloride results in increased secretion of ALB protein] CTD PMID:26732703 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Cat catalase multiple interactions
decreases activity		 EXP [[Sodium Selenite results in increased abundance of Selenium] which co-treated with Ascorbic Acid] inhibits the reaction [barium chloride results in decreased activity of CAT protein]; [barium chloride results in increased abundance of Barium] which results in decreased activity of CAT protein; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [barium chloride results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [barium chloride results in decreased activity of CAT protein]; Plant Extracts inhibits the reaction [barium chloride results in decreased activity of CAT protein] CTD PMID:26732703 PMID:27941167 PMID:28683652 PMID:31407482 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO barium chloride inhibits the reaction [TNF protein results in increased expression of F3 mRNA]; barium chloride inhibits the reaction [TNF protein results in increased expression of F3 protein] CTD PMID:23305835 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases activity EXP barium chloride results in increased activity of GGT1 protein CTD PMID:28683652 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases activity EXP barium chloride results in increased activity of GOT1 protein CTD PMID:28683652 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity EXP barium chloride results in increased activity of GPT protein CTD PMID:28683652 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases activity EXP barium chloride results in decreased activity of GPX1 protein CTD PMID:28683652 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions		 EXP barium chloride results in increased expression of IL1B mRNA
Plant Extracts inhibits the reaction [barium chloride results in increased expression of IL1B mRNA]		 CTD PMID:26732703 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions		 EXP barium chloride results in increased expression of IL6 mRNA
[barium chloride results in increased abundance of Barium] which results in increased expression of IL6 protein; Plant Extracts inhibits the reaction [barium chloride results in increased expression of IL6 mRNA]		 CTD PMID:26732703 PMID:31407482 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 multiple interactions ISO barium chloride results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901 		JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 multiple interactions EXP barium chloride inhibits the reaction [KCNJ2 protein results in increased transport of Potassium] CTD PMID:11087224 NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445 		JBrowse link
G Kcnk3 potassium two pore domain channel subfamily K member 3 decreases activity EXP barium chloride results in decreased activity of KCNK3 protein CTD PMID:16020457 NCBI chr 6:25,761,487...25,799,153
Ensembl chr 6:25,763,228...25,799,153 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 multiple interactions ISO barium chloride results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669 		JBrowse link
G Ldha lactate dehydrogenase A increases activity EXP barium chloride results in increased activity of LDHA protein CTD PMID:28683652 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472 		JBrowse link
G Mt1 metallothionein 1 increases expression
multiple interactions		 EXP barium chloride results in increased expression of MT1 mRNA
Plant Extracts inhibits the reaction [barium chloride results in increased expression of MT1 mRNA]		 CTD PMID:26732703 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049 		JBrowse link
G Mt2A metallothionein 2A increases expression
multiple interactions		 EXP barium chloride results in increased expression of MT2A mRNA
Plant Extracts inhibits the reaction [barium chloride results in increased expression of MT2A mRNA]		 CTD PMID:26732703 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Serpine1 serpin family E member 1 increases secretion EXP barium chloride results in increased secretion of SERPINE1 protein CTD PMID:21596853 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sod2 superoxide dismutase 2 decreases expression
multiple interactions		 EXP barium chloride results in decreased expression of SOD2 mRNA
Plant Extracts inhibits the reaction [barium chloride results in decreased expression of SOD2 mRNA]		 CTD PMID:26732703 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Stx1a syntaxin 1A multiple interactions
affects localization		 EXP Propofol inhibits the reaction [barium chloride affects the localization of STX1A protein]; STX1A protein modified form inhibits the reaction [Propofol inhibits the reaction [barium chloride affects the localization of STX1A protein]] CTD PMID:29320738 NCBI chr12:21,641,971...21,670,022
Ensembl chr12:21,641,969...21,669,930 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 EXP
ISO		 Plant Extracts inhibits the reaction [barium chloride results in increased expression of TNF mRNA]
barium chloride inhibits the reaction [TNF protein results in increased expression of F3 mRNA]; barium chloride inhibits the reaction [TNF protein results in increased expression of F3 protein]		 CTD PMID:23305835 PMID:26732703 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO [barium chloride results in increased abundance of Barium] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:104,217,898...104,277,886
Ensembl chr  X:104,217,925...104,276,861 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19932
    role 19904
      application 19741
        NMR chemical shift reference compound 18097
          barium chloride 22
            barium chloride dihydrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19932
    subatomic particle 19930
      composite particle 19930
        hadron 19930
          baryon 19930
            nucleon 19930
              atomic nucleus 19930
                atom 19930
                  main group element atom 19876
                    p-block element atom 19876
                      halogen 18710
                        chlorine atom 18496
                          chlorine molecular entity 18496
                            elemental chlorine 8805
                              monoatomic chlorine 8790
                                chloride 8790
                                  chloride salt 8790
                                    inorganic chloride 8552
                                      barium chloride 22
                                        barium chloride dihydrate 0
paths to the root