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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:phosphine derivative
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Accession:CHEBI:63258 term browser browse the term
Definition:Any phosphorus molecular entity formed by derivatization of a phosphine.
Synonyms:related_synonym: phosphine derivatives



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TCEP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AS3MT arsenite methyltransferase multiple interactions
affects folding
increases reduction
ISO
EXP
tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased methylation of Arsenic]
tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein binds to and results in increased methylation of arsenite]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein binds to S-Adenosylmethionine]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased chemical synthesis of dimethylarsinous acid]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased chemical synthesis of methylarsonite]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased methylation of arsenite]
tris(2-carboxyethyl)phosphine affects the folding of AS3MT protein
tris(2-carboxyethyl)phosphine results in increased reduction of AS3MT protein
CTD PMID:15025511 PMID:22955273 PMID:25349987 NCBI chr10:102,869,470...102,901,899
Ensembl chr10:102,869,470...102,901,899
JBrowse link
G CRYGD crystallin gamma D decreases oxidation EXP [tris(2-carboxyethyl)phosphine results in decreased oxidation of CRYGD protein] which results in decreased oxidation of CRYGD mRNA mutant form; tris(2-carboxyethyl)phosphine results in decreased oxidation of CRYGD protein CTD PMID:30242128 NCBI chr 2:208,121,607...208,124,524
Ensembl chr 2:208,121,607...208,124,524
JBrowse link
G NEIL1 nei like DNA glycosylase 1 multiple interactions EXP [tris(2-carboxyethyl)phosphine co-treated with Edetic Acid] inhibits the reaction [Copper results in decreased activity of NEIL1 protein]; tris(2-carboxyethyl)phosphine inhibits the reaction [Hydrogen Peroxide results in decreased activity of NEIL1 protein] CTD PMID:20622253 NCBI chr15:75,346,638...75,357,115
Ensembl chr15:75,346,955...75,357,115
JBrowse link
G SLC34A1 solute carrier family 34 member 1 decreases activity ISO tris(2-carboxyethyl)phosphine results in decreased activity of SLC34A1 protein CTD PMID:10926679 NCBI chr 5:177,384,434...177,412,021
Ensembl chr 5:177,379,235...177,398,848
JBrowse link
G TXN thioredoxin multiple interactions EXP tris(2-carboxyethyl)phosphine inhibits the reaction [chromium hexavalent ion results in increased oxidation of TXN protein]; tris(2-carboxyethyl)phosphine inhibits the reaction [sodium chromate(VI) results in increased oxidation of TXN protein] CTD PMID:19135121 PMID:19703554 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507
JBrowse link
G TXN2 thioredoxin 2 multiple interactions EXP tris(2-carboxyethyl)phosphine inhibits the reaction [chromium hexavalent ion results in increased oxidation of TXN2 protein] CTD PMID:19703554 NCBI chr22:36,467,036...36,481,672
Ensembl chr22:36,467,046...36,481,640
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 25189
    role 25112
      chemical role 23270
        catalyst 8549
          phosphine 6
            phosphine derivative 6
              TCEP 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 25189
    subatomic particle 25151
      composite particle 25151
        hadron 25151
          baryon 25151
            nucleon 25151
              atomic nucleus 25151
                atom 25151
                  main group element atom 25031
                    main group molecular entity 25031
                      s-block molecular entity 24299
                        hydrogen molecular entity 23888
                          hydrides 22147
                            inorganic hydride 19503
                              pnictogen hydride 19430
                                phosphorus hydride 6
                                  phosphanes 6
                                    phosphane 6
                                      phosphine derivative 6
                                        TCEP 6
paths to the root