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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:oxidising agent
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Accession:CHEBI:63248 term browser browse the term
Definition:A substance that removes electrons from another reactant in a redox reaction.
Synonyms:related_synonym: oxidant;   oxidants;   oxidiser;   oxidisers;   oxidising agents;   oxidizer;   oxidizers;   oxidizing agent;   oxidizing agents


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dioxygen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP Oxygen inhibits the reaction [Hydrochloric Acid results in increased expression of CXCL8 protein] CTD PMID:18339021 NCBI chr13:62,435,035...62,438,354
Ensembl chr13:62,434,422...62,438,354 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions EXP Oxygen inhibits the reaction [Hydrochloric Acid results in increased expression of MMP2 protein] CTD PMID:18339021 NCBI chr 2:60,471,092...60,492,991
Ensembl chr 2:60,471,257...60,494,113 		JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions EXP Oxygen inhibits the reaction [Hydrochloric Acid results in increased expression of MMP9 protein] CTD PMID:18339021 NCBI chr24:33,274,260...33,281,116
Ensembl chr24:33,274,268...33,281,293 		JBrowse link
hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLDN4 claudin 4 multiple interactions
increases expression		 EXP Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of CLDN4 protein]; Glutathione inhibits the reaction [Hydrogen Peroxide results in increased expression of CLDN4 protein]; pyrazolanthrone inhibits the reaction [Hydrogen Peroxide results in increased expression of CLDN4 protein]; U 0126 inhibits the reaction [Hydrogen Peroxide results in increased expression of CLDN4 protein] CTD PMID:23816505 NCBI chr 6:6,492,706...6,506,750
Ensembl chr 6:6,493,513...6,494,145 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation		 EXP Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]; Glutathione inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein] CTD PMID:23816505 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases phosphorylation
multiple interactions		 EXP Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]; Glutathione inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]		 CTD PMID:23816505 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions		 EXP Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]; Glutathione inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]		 CTD PMID:23816505 NCBI chr28:323,361...410,367
Ensembl chr28:368,513...406,401 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions
increases phosphorylation		 EXP Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein]; Glutathione inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein]; pyrazolanthrone inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein] CTD PMID:23816505 NCBI chr11:1,443,528...1,480,501
Ensembl chr11:1,443,547...1,478,119 		JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions
decreases activity		 EXP Dihydrotestosterone promotes the reaction [Hydrogen Peroxide results in decreased activity of SOD2 protein] CTD PMID:16682413 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706 		JBrowse link
tert-butyl hydroperoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN2A cyclin dependent kinase inhibitor 2A decreases expression EXP tert-Butylhydroperoxide results in decreased expression of CDKN2A protein CTD PMID:14729356 NCBI chr11:41,223,316...41,226,056
Ensembl chr11:41,223,315...41,264,379 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression
decreases expression		 EXP tert-Butylhydroperoxide results in increased expression of GADD45A protein
tert-Butylhydroperoxide results in decreased expression of GADD45A protein		 CTD PMID:14729356 NCBI chr 6:77,393,026...77,396,473
Ensembl chr 6:77,393,036...77,396,618 		JBrowse link
G TERT telomerase reverse transcriptase increases activity EXP tert-Butylhydroperoxide results in increased activity of TERT protein CTD PMID:14729356 NCBI chr34:11,288,622...11,307,790
Ensembl chr34:11,288,622...11,307,951 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 402
    role 402
      chemical role 328
        oxidising agent 12
          acetaldehyde + 0
          aldrithiol 0
          ammonium nitrate + 0
          ammonium persulfate 0
          chromate(2-) + 0
          chromic acid + 0
          cumene hydroperoxide 0
          dinitrogen tetraoxide 0
          dioxygen + 3
          hydrogen peroxide + 6
          hypothiocyanous acid 0
          lead tetraacetate 0
          lithium nitrate 0
          nitryl chloride 0
          osmium tetroxide 0
          ozone 0
          peracetic acid 0
          potassium chromate 0
          potassium dichromate 0
          pyridinium chlorochromate 0
          pyridinium dichromate 0
          sodium bromate 0
          sodium chlorite 0
          sodium chromate 0
          sodium periodate 0
          tert-butyl hydroperoxide 3
          urea hydrogen peroxide 0
paths to the root