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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:manganese(II) chloride
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Accession:CHEBI:63041 term browser browse the term
Definition:An inorganic chloride in which manganese(II) is coordinated to two chloride ions. In its anhydrous state manganese(II) chloride is a polymeric solid, which adopts a layered cadmium chloride-like structure.
Synonyms:exact_synonym: manganese(2+) dichloride
 related_synonym: Formula=Cl2Mn;   InChI=1S/2ClH.Mn/h2*1H;/q;;+2/p-2;   InChIKey=GLFNIEUTAYBVOC-UHFFFAOYSA-L;   Mangandichlorid;   Manganese bichloride;   Manganese(II) chloride (1:2);   Manganous chloride;   SMILES=Cl[Mn]Cl;   dichlorure de manganese;   manganese(II) dichloride;   manganous dichloride
 xref: CAS:7773-01-5
 xref_mesh: MESH:C025340
 xref: MetaCyc:CPD0-2394;   PMID:101555;   PMID:146543;   PMID:19801673;   PMID:3143594;   PMID:4476198;   PMID:4771199;   PMID:98204;   Reaxys:8128170;   Wikipedia:Manganese(II)_chloride


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manganese(II) chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca5 ATP binding cassette subfamily A member 5 decreases expression ISO manganese chloride results in decreased expression of ABCA5 mRNA CTD PMID:17175027 NCBI chr10:98,573,226...98,645,028
Ensembl chr10:98,576,039...98,644,938
JBrowse link
G Abca9 ATP binding cassette subfamily A member 9 increases expression ISO manganese chloride results in increased expression of ABCA9 mRNA CTD PMID:17175027 NCBI chr10:98,412,263...98,472,258
Ensembl chr10:98,412,263...98,469,799
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression EXP manganese chloride results in increased expression of ABCB1A mRNA CTD PMID:26745496 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP manganese chloride results in increased expression of ABCB1B mRNA CTD PMID:28801915 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression
decreases methylation
EXP manganese chloride results in increased expression of ABCC2 mRNA
manganese chloride results in decreased methylation of ABCC2 gene
CTD PMID:28801915 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc8 ATP binding cassette subfamily C member 8 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in increased expression of ABCC8 protein CTD PMID:32659473 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Abi2 abl-interactor 2 increases expression ISO manganese chloride results in increased expression of ABI2 mRNA CTD PMID:17175027 NCBI chr 9:67,234,612...67,284,504
Ensembl chr 9:67,234,303...67,282,600
JBrowse link
G Abitram actin binding transcription modulator increases expression EXP manganese chloride results in increased expression of ABITRAM mRNA CTD PMID:28801915 NCBI chr 5:73,552,952...73,560,240
Ensembl chr 5:73,552,983...73,556,987
JBrowse link
G Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 increases expression EXP manganese chloride results in increased expression of ACAP1 mRNA CTD PMID:28801915 NCBI chr10:56,492,300...56,506,446
Ensembl chr10:56,492,300...56,506,446
JBrowse link
G Ace angiotensin I converting enzyme increases expression EXP manganese chloride results in increased expression of ACE mRNA CTD PMID:28801915 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ache acetylcholinesterase increases activity
multiple interactions
decreases activity
increases expression
EXP
ISO
manganese chloride results in increased activity of ACHE protein
[manganese chloride results in increased abundance of Manganese] which results in decreased activity of ACHE protein; [manganese chloride results in increased abundance of Manganese] which results in increased activity of ACHE protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of ACHE mRNA alternative form
manganese chloride results in decreased activity of ACHE protein
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased activity of ACHE protein]; [manganese chloride results in increased abundance of Manganese] which results in increased activity of ACHE protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased activity of ACHE protein]; Lycopene inhibits the reaction [manganese chloride results in increased activity of ACHE protein]; Silymarin inhibits the reaction [manganese chloride results in decreased activity of ACHE protein]; Silymarin inhibits the reaction [manganese chloride results in increased activity of ACHE protein]; Silymarin inhibits the reaction [manganese chloride results in increased expression of ACHE mRNA]
CTD PMID:20503066 PMID:22033861 PMID:22154916 PMID:22192907 PMID:30738988 PMID:30844427 PMID:32445656 PMID:33314588 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Aco1 aconitase 1 increases activity EXP manganese chloride results in increased activity of ACO1 protein CTD PMID:15893546 PMID:16545456 PMID:16568477 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
JBrowse link
G Aco2 aconitase 2 multiple interactions
decreases activity
decreases expression
ISO
EXP
ferric ammonium citrate inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]
Iron inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]
manganese chloride results in decreased expression of ACO2 mRNA; manganese chloride results in decreased expression of ACO2 protein
CTD PMID:9675333 PMID:16625280 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression EXP manganese chloride results in increased expression of ACOT2 mRNA CTD PMID:28801915 NCBI chr 6:107,460,596...107,468,324
Ensembl chr 6:107,460,668...107,467,487
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant increases expression
increases methylation
EXP manganese chloride results in increased expression of ACP5 mRNA
manganese chloride results in increased methylation of ACP5 gene
CTD PMID:22281203 PMID:28801915 NCBI chr 8:23,142,733...23,149,067
Ensembl chr 8:23,142,734...23,148,396
JBrowse link
G Acr acrosin increases expression EXP manganese chloride results in increased expression of ACR mRNA CTD PMID:28801915 NCBI chr 7:130,541,320...130,548,356
Ensembl chr 7:130,542,202...130,548,356
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression ISO manganese chloride results in decreased expression of ACSL3 mRNA CTD PMID:15295902 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 decreases expression EXP manganese chloride results in decreased expression of ACSS2 mRNA CTD PMID:28801915 NCBI chr 3:151,032,925...151,075,856
Ensembl chr 3:151,032,952...151,075,856
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle decreases expression EXP manganese chloride results in decreased expression of ACTA1 mRNA CTD PMID:26745496 NCBI chr19:56,674,072...56,677,084
Ensembl chr19:56,674,074...56,677,084
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression EXP manganese chloride results in increased expression of ACTA2 mRNA CTD PMID:28801915 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Actb actin, beta decreases expression
increases expression
ISO manganese chloride results in decreased expression of ACTB protein
manganese chloride results in increased expression of ACTB mRNA
CTD PMID:20452446 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Acvrl1 activin A receptor like type 1 increases expression EXP manganese chloride results in increased expression of ACVRL1 mRNA CTD PMID:28801915 NCBI chr 7:142,769,942...142,787,336
Ensembl chr 7:142,776,252...142,787,335
JBrowse link
G Adam19 ADAM metallopeptidase domain 19 increases expression EXP manganese chloride results in increased expression of ADAM19 mRNA CTD PMID:28801915 NCBI chr10:31,146,107...31,240,582
Ensembl chr10:31,146,107...31,240,582
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 decreases expression EXP manganese chloride results in decreased expression of ADAMTS1 mRNA CTD PMID:28801915 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 decreases expression EXP manganese chloride results in decreased expression of ADAMTS5 mRNA CTD PMID:28801915 NCBI chr11:25,411,174...25,456,639
Ensembl chr11:25,410,975...25,456,836
JBrowse link
G Adcy6 adenylate cyclase 6 increases expression EXP manganese chloride results in increased expression of ADCY6 mRNA CTD PMID:28801915 NCBI chr 7:140,270,678...140,291,722
Ensembl chr 7:140,270,692...140,291,620
JBrowse link
G Add2 adducin 2 increases expression EXP manganese chloride results in increased expression of ADD2 mRNA CTD PMID:28801915 NCBI chr 4:117,691,294...117,887,556
Ensembl chr 4:117,743,710...117,882,464
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression EXP manganese chloride results in increased expression of ADIPOQ mRNA CTD PMID:28801915 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adm adrenomedullin increases expression
decreases expression
ISO
EXP
manganese chloride results in increased expression of ADM mRNA
manganese chloride results in decreased expression of ADM mRNA
CTD PMID:17175027 PMID:28801915 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Adora2a adenosine A2a receptor increases expression EXP manganese chloride results in increased expression of ADORA2A mRNA CTD PMID:28801915 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Aen apoptosis enhancing nuclease increases expression EXP manganese chloride results in increased expression of AEN mRNA CTD PMID:28801915 NCBI chr 1:140,584,328...140,593,749
Ensembl chr 1:140,584,380...140,593,745
JBrowse link
G Aff1 AF4/FMR2 family, member 1 increases expression EXP manganese chloride results in increased expression of AFF1 mRNA CTD PMID:28801915 NCBI chr14:7,222,883...7,384,916
Ensembl chr14:7,226,586...7,384,876
JBrowse link
G Afmid arylformamidase increases expression EXP manganese chloride results in increased expression of AFMID mRNA CTD PMID:28801915 NCBI chr10:106,828,963...106,844,314
Ensembl chr10:106,828,981...106,844,314
JBrowse link
G Afp alpha-fetoprotein decreases expression EXP manganese chloride results in decreased expression of AFP mRNA CTD PMID:26745496 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Ahnak2 AHNAK nucleoprotein 2 increases expression EXP manganese chloride results in increased expression of AHNAK2 mRNA CTD PMID:28801915 NCBI chr 6:137,335,273...137,380,219 JBrowse link
G Aicda activation-induced cytidine deaminase increases expression EXP manganese chloride results in increased expression of AICDA mRNA CTD PMID:28801915 NCBI chr 4:155,359,909...155,371,104
Ensembl chr 4:155,359,921...155,369,671
JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression ISO manganese chloride results in increased expression of AIF1 protein CTD PMID:28595911 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Akap7 A-kinase anchoring protein 7 decreases expression ISO manganese chloride results in decreased expression of AKAP7 mRNA CTD PMID:17175027 NCBI chr 1:21,129,213...21,263,850
Ensembl chr 1:21,141,970...21,263,850
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression EXP manganese chloride results in increased expression of AKR1B1 mRNA CTD PMID:22281203 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions
EXP
ISO
manganese chloride results in decreased phosphorylation of AKT1 protein
[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of AKT1 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of AKT1 protein]
NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of AKT1 protein]
CTD PMID:30040983 PMID:31676349 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin multiple interactions EXP [sodium arsenite co-treated with Cadmium Chloride co-treated with lead acetate co-treated with Mercuric Chloride co-treated with chromium trioxide co-treated with nickel chloride co-treated with manganese chloride co-treated with ferric chloride] results in decreased expression of ALB protein CTD PMID:17657459 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 increases expression EXP manganese chloride results in increased expression of ALDH18A1 mRNA CTD PMID:28801915 NCBI chr 1:259,641,673...259,674,521
Ensembl chr 1:259,641,676...259,674,425
Ensembl chr 1:259,641,676...259,674,425
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression EXP manganese chloride results in decreased expression of ALDH1A1 mRNA CTD PMID:28801915 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 increases expression EXP manganese chloride results in increased expression of ALDH4A1 mRNA CTD PMID:28801915 NCBI chr 5:158,090,238...158,115,725
Ensembl chr 5:158,042,587...158,135,733
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression EXP manganese chloride results in increased expression of ALDOA mRNA CTD PMID:22281203 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression EXP manganese chloride results in decreased expression of ALDOC mRNA CTD PMID:28801915 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Alkal1 ALK and LTK ligand 1 increases expression EXP manganese chloride results in increased expression of ALKAL1 mRNA CTD PMID:28801915 NCBI chr 5:12,896,136...12,925,571
Ensembl chr 5:12,896,558...12,925,571
JBrowse link
G Amigo3 adhesion molecule with Ig like domain 3 increases expression EXP manganese chloride results in increased expression of AMIGO3 mRNA CTD PMID:28801915 NCBI chr 8:116,830,773...116,832,299 JBrowse link
G Angpt2 angiopoietin 2 decreases expression EXP manganese chloride results in decreased expression of ANGPT2 mRNA CTD PMID:26745496 NCBI chr16:75,966,480...76,016,147
Ensembl chr16:75,966,352...76,016,195
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO manganese chloride results in increased expression of ANGPTL4 mRNA CTD PMID:17175027 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Ankrd28 ankyrin repeat domain 28 increases expression EXP manganese chloride results in increased expression of ANKRD28 mRNA CTD PMID:28801915 NCBI chr16:7,816,876...7,879,023
Ensembl chr16:7,818,667...7,928,518
JBrowse link
G Ano3 anoctamin 3 increases expression EXP manganese chloride results in increased expression of ANO3 mRNA CTD PMID:28801915 NCBI chr 3:101,843,516...102,203,368
Ensembl chr 3:101,840,630...102,151,489
JBrowse link
G Anxa3 annexin A3 decreases expression EXP manganese chloride results in decreased expression of ANXA3 mRNA CTD PMID:28801915 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
JBrowse link
G Aopep aminopeptidase O decreases expression EXP manganese chloride results in decreased expression of AOPEP mRNA CTD PMID:28801915 NCBI chr17:507,389...825,062
Ensembl chr17:507,377...821,582
JBrowse link
G Ap3b2 adaptor related protein complex 3 subunit beta 2 increases expression ISO manganese chloride results in increased expression of AP3B2 mRNA CTD PMID:17175027 NCBI chr 1:143,284,041...143,315,846
Ensembl chr 1:143,283,996...143,315,633
JBrowse link
G Apbb3 amyloid beta precursor protein binding family B member 3 increases expression EXP manganese chloride results in increased expression of APBB3 mRNA CTD PMID:28801915 NCBI chr18:29,497,865...29,504,995
Ensembl chr18:29,497,863...29,504,995
JBrowse link
G Apc APC regulator of WNT signaling pathway decreases expression
increases methylation
ISO manganese chloride results in decreased expression of APC mRNA
manganese chloride results in increased methylation of APC gene
CTD PMID:27913844 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Apoa2 apolipoprotein A2 decreases expression EXP manganese chloride results in decreased expression of APOA2 mRNA CTD PMID:28801915 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
G Apol2 apolipoprotein L, 2 increases expression ISO manganese chloride results in increased expression of APOL2 mRNA CTD PMID:17175027 NCBI chr 7:118,727,658...118,735,453
Ensembl chr 7:118,728,617...118,732,738
Ensembl chr 7:118,728,617...118,732,738
JBrowse link
G Apold1 apolipoprotein L domain containing 1 increases expression EXP manganese chloride results in increased expression of APOLD1 mRNA CTD PMID:28801915 NCBI chr 4:168,752,142...168,755,024
Ensembl chr 4:168,752,133...168,755,023
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) decreases expression EXP manganese chloride results in decreased expression of AQP3 mRNA CTD PMID:28801915 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Areg amphiregulin increases expression EXP manganese chloride results in increased expression of AREG mRNA CTD PMID:28801915 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arg1 arginase 1 increases expression
increases methylation
EXP manganese chloride results in increased expression of ARG1 mRNA
manganese chloride results in increased methylation of ARG1 gene
CTD PMID:28801915 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Arhgap24 Rho GTPase activating protein 24 decreases expression EXP manganese chloride results in decreased expression of ARHGAP24 mRNA CTD PMID:28801915 NCBI chr14:8,383,211...8,600,526
Ensembl chr14:8,383,214...8,600,512
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO manganese chloride results in decreased expression of ARHGDIA mRNA CTD PMID:17175027 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 increases expression EXP manganese chloride results in increased expression of ARHGEF10 mRNA CTD PMID:28801915 NCBI chr16:79,725,629...79,817,065
Ensembl chr16:79,725,643...79,793,619
JBrowse link
G Arhgef16 Rho guanine nucleotide exchange factor 16 increases expression EXP manganese chloride results in increased expression of ARHGEF16 mRNA CTD PMID:28801915 NCBI chr 5:171,626,450...171,649,124
Ensembl chr 5:171,624,796...171,648,563
JBrowse link
G Arhgef4 Rho guanine nucleotide exchange factor 4 increases expression
increases methylation
ISO
EXP
manganese chloride results in increased expression of ARHGEF4 mRNA
manganese chloride results in increased methylation of ARHGEF4 gene
CTD PMID:17175027 PMID:28801915 NCBI chr 9:41,160,562...41,305,015
Ensembl chr 9:41,295,909...41,302,501
JBrowse link
G Arhgef6 Rac/Cdc42 guanine nucleotide exchange factor 6 increases expression EXP manganese chloride results in increased expression of ARHGEF6 mRNA CTD PMID:28801915 NCBI chr  X:159,722,031...159,841,344
Ensembl chr  X:159,723,866...159,841,072
JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor 7 decreases expression EXP manganese chloride results in decreased expression of ARHGEF7 mRNA CTD PMID:28801915 NCBI chr16:83,006,732...83,117,065
Ensembl chr16:83,006,718...83,132,785
JBrowse link
G Arid3a AT-rich interaction domain 3A increases expression EXP manganese chloride results in increased expression of ARID3A mRNA CTD PMID:28801915 NCBI chr 7:12,573,604...12,602,407
Ensembl chr 7:12,574,198...12,601,674
JBrowse link
G Arl4c ADP ribosylation factor like GTPase 4C increases methylation
increases expression
EXP manganese chloride results in increased methylation of ARL4C gene
manganese chloride results in increased expression of ARL4C mRNA
CTD PMID:28801915 NCBI chr 9:95,783,651...95,787,092
Ensembl chr 9:95,786,508...95,787,094
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO ARNT gene mutant form inhibits the reaction [manganese chloride results in increased secretion of VEGFA protein] CTD PMID:19263519 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases expression EXP manganese chloride results in decreased expression of ARNTL mRNA CTD PMID:28511934 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Asb5 ankyrin repeat and SOCS box-containing 5 decreases expression EXP manganese chloride results in decreased expression of ASB5 mRNA CTD PMID:28801915 NCBI chr16:39,985,233...40,050,663
Ensembl chr16:39,985,234...40,025,401
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression EXP manganese chloride results in increased expression of ASNS mRNA CTD PMID:28801915 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Ass1 argininosuccinate synthase 1 increases expression EXP manganese chloride results in increased expression of ASS1 mRNA CTD PMID:28801915 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Aste1 asteroid homolog 1 increases expression EXP manganese chloride results in increased expression of ASTE1 mRNA CTD PMID:28801915 NCBI chr 8:113,936,991...113,954,833
Ensembl chr 8:113,936,991...113,954,832
JBrowse link
G Atf1 activating transcription factor 1 increases phosphorylation
multiple interactions
EXP manganese chloride results in increased phosphorylation of ATF1 protein
SB 203580 inhibits the reaction [manganese chloride results in increased phosphorylation of ATF1 protein]
CTD PMID:16787641 NCBI chr 7:141,882,261...141,924,790
Ensembl chr 7:141,882,251...141,924,788
JBrowse link
G Atf2 activating transcription factor 2 increases activity
increases phosphorylation
ISO manganese chloride results in increased activity of ATF2 protein
manganese chloride results in increased phosphorylation of ATF2 protein
CTD PMID:19084589 PMID:20152896 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression
EXP manganese chloride promotes the reaction [EIF2AK3 protein results in increased expression of ATF4 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of ATF4 mRNA]
manganese chloride results in increased expression of ATF4 mRNA; manganese chloride results in increased expression of ATF4 protein
CTD PMID:23934647 PMID:23948121 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atf6 activating transcription factor 6 decreases expression
increases expression
ISO
EXP
manganese chloride results in decreased expression of ATF6 mRNA
manganese chloride results in increased expression of ATF6 protein
CTD PMID:17175027 PMID:25732873 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atm ATM serine/threonine kinase decreases expression ISO manganese chloride results in decreased expression of ATM mRNA CTD PMID:17175027 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 decreases expression EXP manganese chloride results in decreased expression of ATOH8 mRNA CTD PMID:26745496 PMID:28801915 NCBI chr 4:100,067,341...100,099,517
Ensembl chr 4:100,067,341...100,099,517
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 increases methylation EXP manganese chloride results in increased methylation of ATP2A3 gene CTD PMID:28801915 NCBI chr10:59,528,849...59,560,440
Ensembl chr10:59,529,785...59,560,433
JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 increases methylation
decreases expression
ISO manganese chloride results in increased methylation of ATP2B2 gene
manganese chloride results in decreased expression of ATP2B2 mRNA
CTD PMID:27913844 NCBI chr 4:145,704,779...145,948,997
Ensembl chr 4:145,703,046...146,016,325
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 increases expression EXP manganese chloride results in increased expression of ATP2B4 mRNA CTD PMID:28801915 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma decreases expression EXP manganese chloride results in decreased expression of ATP5C1 mRNA CTD PMID:22281203 NCBI chr17:72,209,321...72,231,562
Ensembl chr17:72,209,373...72,394,271
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A increases expression EXP manganese chloride results in increased expression of ATP6V1A mRNA CTD PMID:28801915 NCBI chr11:61,531,386...61,584,634
Ensembl chr11:61,531,416...61,584,634
JBrowse link
G Atp6v1e2 ATPase H+ transporting V1 subunit E2 decreases expression EXP
ISO
manganese chloride results in decreased expression of ATP6V1E2 mRNA CTD PMID:28801915 NCBI chr 6:10,510,370...10,517,059
Ensembl chr 6:10,511,452...10,515,370
JBrowse link
G Atp7a ATPase copper transporting alpha decreases expression
affects localization
EXP manganese chloride results in decreased expression of ATP7A mRNA; manganese chloride results in decreased expression of ATP7A protein
manganese chloride affects the localization of ATP7A protein
CTD PMID:24614235 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Atp7b ATPase copper transporting beta affects localization
decreases expression
EXP manganese chloride affects the localization of ATP7B protein
manganese chloride results in decreased expression of ATP7B mRNA; manganese chloride results in decreased expression of ATP7B protein
CTD PMID:24614235 NCBI chr16:74,865,516...74,944,935
Ensembl chr16:74,865,516...74,945,286
JBrowse link
G Atp8a1 ATPase phospholipid transporting 8A1 decreases expression ISO manganese chloride results in decreased expression of ATP8A1 mRNA CTD PMID:17175027 NCBI chr14:41,972,398...42,210,555
Ensembl chr14:42,015,347...42,206,311
JBrowse link
G Avil advillin decreases expression
increases methylation
EXP manganese chloride results in decreased expression of AVIL mRNA
manganese chloride results in increased methylation of AVIL gene
CTD PMID:28801915 NCBI chr 7:70,292,565...70,310,588
Ensembl chr 7:70,292,565...70,310,588
JBrowse link
G Axin2 axin 2 increases expression EXP manganese chloride results in increased expression of AXIN2 mRNA CTD PMID:28801915 NCBI chr10:97,212,483...97,238,824
Ensembl chr10:97,212,432...97,239,642
JBrowse link
G Bach1 BTB domain and CNC homolog 1 increases expression EXP manganese chloride results in increased expression of BACH1 mRNA CTD PMID:28801915 NCBI chr11:27,364,913...27,398,713
Ensembl chr11:27,364,916...27,398,842
Ensembl chr11:27,364,916...27,398,842
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
EXP
ISO
manganese chloride results in increased expression of BAX mRNA; manganese chloride results in increased expression of BAX protein
NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein]
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased expression of BAX protein]; [manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein]; manganese chloride results in increased expression of and affects the localization of BAX protein
[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein; [Plant Extracts co-treated with manganese chloride] affects the expression of BAX protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein]; Estradiol inhibits the reaction [manganese chloride results in increased expression of BAX protein]; Tamoxifen inhibits the reaction [manganese chloride results in increased expression of BAX protein]
CTD PMID:17623882 PMID:21704098 PMID:25732873 PMID:26064043 PMID:29183790 PMID:30844427 PMID:30951808 PMID:31676349 PMID:33314588 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
increases expression
multiple interactions
increases nitrosation
EXP
ISO
manganese chloride results in decreased expression of BCL2 mRNA; manganese chloride results in decreased expression of BCL2 protein
manganese chloride results in increased expression of BCL2 protein
manganese chloride results in increased expression of BCL2 mRNA
corynoxine B inhibits the reaction [manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]]; manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]; manganese chloride results in increased expression of and results in decreased phosphorylation of BCL2 protein; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride results in increased expression of and results in decreased phosphorylation of BCL2 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride results in increased nitrosation of BCL2 protein]
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in decreased expression of BCL2 protein]; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of BCL2 protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of BCL2 protein]; manganese chloride results in decreased expression of and affects the localization of BCL2 protein
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of BCL2 protein; [Plant Extracts co-treated with manganese chloride] affects the expression of BCL2 protein; Estradiol inhibits the reaction [manganese chloride results in decreased expression of BCL2 protein]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of BCL2 protein]
CTD PMID:17623882 PMID:21704098 PMID:25732873 PMID:26064043 PMID:28801915 PMID:28856835 PMID:29183790 PMID:30578841 PMID:30844427 PMID:30951808 PMID:31676349 PMID:33314588 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression EXP manganese chloride results in decreased expression of BCL2L1 protein CTD PMID:27107493 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression
decreases expression
EXP manganese chloride results in increased expression of BCL2L11 protein
manganese chloride results in decreased expression of BCL2L11 mRNA
CTD PMID:25732873 PMID:28801915 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bcl6b BCL6B, transcription repressor increases expression EXP manganese chloride results in increased expression of BCL6B mRNA CTD PMID:28801915 NCBI chr10:56,834,363...56,840,058
Ensembl chr10:56,834,364...56,839,437
JBrowse link
G Bdkrb2 bradykinin receptor B2 increases expression EXP manganese chloride results in increased expression of BDKRB2 mRNA CTD PMID:28801915 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression
multiple interactions
increases methylation
increases expression
ISO
EXP
manganese chloride results in decreased expression of BDNF mRNA
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of BDNF protein
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of BDNF protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of BDNF mRNA; CREB1 protein affects the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BDNF mRNA]
manganese chloride results in increased methylation of BDNF gene
manganese chloride results in increased expression of BDNF mRNA
CTD PMID:25698507 PMID:28801915 PMID:30951808 PMID:32659473 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 increases expression
affects expression
multiple interactions
decreases expression
EXP
ISO
manganese chloride results in increased expression of BECN1 protein
manganese chloride affects the expression of BECN1 protein
corynoxine B affects the reaction [manganese chloride affects the reaction [HMGB1 protein binds to BECN1 protein]]; corynoxine B inhibits the reaction [manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]]; manganese chloride affects the reaction [HMGB1 protein binds to BECN1 protein]; manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]]
manganese chloride results in decreased expression of BECN1 protein
wortmannin inhibits the reaction [manganese chloride results in increased expression of BECN1 protein]
CTD PMID:23604964 PMID:28856835 PMID:30578841 PMID:30672645 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression EXP manganese chloride results in increased expression of BHLHE40 mRNA CTD PMID:28801915 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Bid BH3 interacting domain death agonist increases cleavage
multiple interactions
increases expression
EXP manganese chloride results in increased cleavage of BID protein
bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased expression of BID protein]; pepstatin inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; pepstatin inhibits the reaction [manganese chloride results in increased expression of BID protein]
manganese chloride results in increased expression of BID protein; manganese chloride results in increased expression of BID protein modified form
CTD PMID:21704098 PMID:28378122 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression
EXP Lithium Chloride inhibits the reaction [manganese chloride results in decreased expression of BIRC5 mRNA] CTD PMID:24464479 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 increases expression EXP manganese chloride results in increased expression of BIRC7 mRNA CTD PMID:28801915 NCBI chr 3:176,438,335...176,443,864
Ensembl chr 3:176,439,199...176,443,195
JBrowse link
G Bloc1s3 biogenesis of lysosomal organelles complex-1, subunit 3 increases expression EXP manganese chloride results in increased expression of BLOC1S3 mRNA CTD PMID:28801915 NCBI chr 1:80,414,766...80,417,385
Ensembl chr 1:80,415,686...80,416,273
JBrowse link
G Blvra biliverdin reductase A increases expression EXP manganese chloride results in increased expression of BLVRA mRNA CTD PMID:22281203 NCBI chr 3:119,552,550...119,577,796
Ensembl chr 3:119,561,290...119,577,806
JBrowse link
G Bmf Bcl2 modifying factor decreases expression EXP manganese chloride results in decreased expression of BMF mRNA CTD PMID:28801915 NCBI chr 3:110,303,515...110,324,125
Ensembl chr 3:110,306,067...110,324,084
JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression ISO manganese chloride results in increased expression of BMP4 mRNA CTD PMID:17467022 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bnip3 BCL2 interacting protein 3 multiple interactions
affects response to substance
ISO [N-(3-(aminomethyl)benzyl)acetamidine results in decreased activity of NOS2 protein] inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; Acetylcysteine inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; BNIP3 protein affects the reaction [manganese chloride affects the localization of CYCS protein]; Cycloheximide inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; Dactinomycin inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; Glutathione inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; manganese chloride results in increased expression of and affects the localization of BNIP3 protein
BNIP3 protein affects the susceptibility to manganese chloride
CTD PMID:19442826 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Bpifb6 BPI fold containing family B, member 6 increases expression EXP manganese chloride results in increased expression of BPIFB6 mRNA CTD PMID:28801915 NCBI chr 3:149,382,312...149,396,130
Ensembl chr 3:149,391,929...149,396,130
JBrowse link
G Bsn bassoon (presynaptic cytomatrix protein) increases expression EXP manganese chloride results in increased expression of BSN mRNA CTD PMID:28801915 NCBI chr 8:116,873,721...116,965,396
Ensembl chr 8:116,873,721...116,965,396
JBrowse link
G Btnl5 butyrophilin-like 5 decreases expression EXP manganese chloride results in decreased expression of BTNL5 mRNA CTD PMID:28801915 NCBI chr20:2,723,576...2,733,181
Ensembl chr20:2,723,572...2,734,296
Ensembl chr20:2,723,572...2,734,296
JBrowse link
G Btnl7 butyrophilin-like 7 decreases expression EXP manganese chloride results in decreased expression of BTNL7 mRNA CTD PMID:28801915 NCBI chr20:2,757,008...2,769,215
Ensembl chr20:2,757,004...2,768,426
Ensembl chr20:2,757,004...2,768,426
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO manganese chloride results in decreased expression of BUB1 mRNA CTD PMID:17175027 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G C1qtnf4 C1q and TNF related 4 increases expression EXP manganese chloride results in increased expression of C1QTNF4 mRNA CTD PMID:28801915 NCBI chr 3:79,713,580...79,718,018
Ensembl chr 3:79,713,567...79,718,025
JBrowse link
G C2cd4b C2 calcium-dependent domain containing 4B increases expression EXP manganese chloride results in increased expression of C2CD4B mRNA CTD PMID:28801915 NCBI chr 8:73,555,414...73,580,848
Ensembl chr 8:73,593,310...73,594,332
JBrowse link
G C4bpa complement component 4 binding protein, alpha decreases expression EXP manganese chloride results in decreased expression of C4BPA mRNA CTD PMID:28801915 NCBI chr13:47,342,090...47,377,580
Ensembl chr13:47,342,079...47,377,703
JBrowse link
G C5 complement C5 decreases expression EXP manganese chloride results in decreased expression of C5 mRNA CTD PMID:28801915 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
JBrowse link
G Ca5b carbonic anhydrase 5B decreases expression EXP manganese chloride results in decreased expression of CAR5B mRNA CTD PMID:28801915 NCBI chr  X:32,232,106...32,291,124
Ensembl chr  X:32,232,142...32,292,072
JBrowse link
G Ca8 carbonic anhydrase 8 increases expression EXP manganese chloride results in increased expression of CAR8 mRNA CTD PMID:26745496 NCBI chr 5:21,249,018...21,345,810
Ensembl chr 5:21,249,020...21,345,810
JBrowse link
G Cables1 Cdk5 and Abl enzyme substrate 1 decreases expression EXP manganese chloride results in decreased expression of CABLES1 mRNA CTD PMID:28801915 NCBI chr18:3,317,724...3,421,721
Ensembl chr18:3,317,724...3,421,721
JBrowse link
G Calcoco2 calcium binding and coiled-coil domain 2 increases expression ISO manganese chloride results in increased expression of CALCOCO2 mRNA CTD PMID:17175027 NCBI chr10:83,935,087...83,963,750 JBrowse link
G Cald1 caldesmon 1 increases expression EXP manganese chloride results in increased expression of CALD1 mRNA CTD PMID:28801915 NCBI chr 4:62,103,948...62,291,375
Ensembl chr 4:62,220,736...62,291,489
JBrowse link
G Caly calcyon neuron-specific vesicular protein increases expression EXP manganese chloride results in increased expression of CALY mRNA CTD PMID:28801915 NCBI chr 1:212,537,851...212,549,040
Ensembl chr 1:212,537,848...212,549,477
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 increases expression ISO manganese chloride results in increased expression of CAMKK2 mRNA CTD PMID:15295902 NCBI chr12:39,253,409...39,302,601
Ensembl chr12:39,253,409...39,302,601
JBrowse link
G Camkv CaM kinase-like vesicle-associated decreases expression EXP manganese chloride results in decreased expression of CAMKV mRNA CTD PMID:28801915 NCBI chr 8:116,715,755...116,730,061
Ensembl chr 8:116,715,755...116,730,061
JBrowse link
G Camp cathelicidin antimicrobial peptide increases expression EXP manganese chloride results in increased expression of CAMP mRNA CTD PMID:28801915 NCBI chr 8:117,930,557...117,932,371
Ensembl chr 8:117,930,546...117,932,518
JBrowse link
G Camta2 calmodulin binding transcription activator 2 increases expression EXP manganese chloride results in increased expression of CAMTA2 mRNA CTD PMID:28801915 NCBI chr10:57,291,192...57,309,638
Ensembl chr10:57,291,192...57,309,298
JBrowse link
G Capn5 calpain 5 increases expression EXP manganese chloride results in increased expression of CAPN5 mRNA CTD PMID:28801915 NCBI chr 1:163,073,134...163,129,736
Ensembl chr 1:163,073,124...163,129,641
JBrowse link
G Card14 caspase recruitment domain family, member 14 increases methylation ISO manganese chloride results in increased methylation of CARD14 gene CTD PMID:27913844 NCBI chr10:108,440,480...108,469,012
Ensembl chr10:108,440,950...108,468,310
JBrowse link
G Card9 caspase recruitment domain family, member 9 decreases expression EXP manganese chloride results in decreased expression of CARD9 mRNA CTD PMID:28801915 NCBI chr 3:3,798,346...3,806,841
Ensembl chr 3:3,798,347...3,806,713
JBrowse link
G Casp12 caspase 12 multiple interactions
increases cleavage
increases expression
ISO
EXP
Deferoxamine promotes the reaction [manganese chloride results in increased cleavage of and results in increased activity of CASP12 protein]; manganese chloride results in increased cleavage of and results in increased activity of CASP12 protein
Plant Extracts inhibits the reaction [manganese chloride results in increased cleavage of CASP12 protein]
SNCA protein promotes the reaction [manganese chloride results in increased expression of CASP12 protein]
manganese chloride results in increased expression of CASP12 mRNA; manganese chloride results in increased expression of CASP12 protein
CTD PMID:23764342 PMID:23934647 PMID:23948121 PMID:25732873 PMID:26064043 PMID:28801915 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp2 caspase 2 increases expression EXP manganese chloride results in increased expression of CASP2 mRNA CTD PMID:28801915 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 increases cleavage
increases methylation
increases expression
increases activity
multiple interactions
ISO
EXP
manganese chloride results in increased cleavage of CASP3 protein
manganese chloride results in increased methylation of CASP3 gene
manganese chloride results in increased expression of CASP3 protein
manganese chloride results in increased activity of CASP3 protein
Deferoxamine promotes the reaction [manganese chloride results in increased activity of CASP3 protein]; SNCA protein inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]
[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein; Plant Extracts inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; PRNP protein inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]
manganese chloride results in increased expression of CASP3 mRNA; manganese chloride results in increased expression of CASP3 protein; manganese chloride results in increased expression of CASP3 protein modified form
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased expression of CASP3 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of CASP3 protein; Acetylcysteine inhibits the reaction [manganese chloride results in increased expression of CASP3 protein modified form]; bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of CASP3 protein]; GW 506033X inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein]; Lithium Chloride inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]; pepstatin inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [manganese chloride results in increased expression of CASP3 protein]; Quercetin inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]; rhodioloside inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein]; U 0126 inhibits the reaction [manganese chloride results in increased expression of CASP3 mRNA]; U 0126 inhibits the reaction [manganese chloride results in increased expression of CASP3 protein]
CTD PMID:16787641 PMID:17483122 PMID:18178165 PMID:19815061 PMID:23764342 PMID:24464479 PMID:25416158 PMID:25732873 PMID:26064043 PMID:27913844 PMID:28040552 PMID:28378122 PMID:28778520 PMID:30844427 PMID:30991096 PMID:31676349 PMID:32574669 PMID:33314588 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 increases expression EXP manganese chloride results in increased expression of CASP4 mRNA CTD PMID:28801915 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Casp8 caspase 8 increases cleavage
multiple interactions
EXP manganese chloride results in increased cleavage of CASP8 protein
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein]; pepstatin inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein]
CTD PMID:21704098 PMID:28378122 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions
increases cleavage
ISO
EXP
manganese chloride results in increased activity of CASP9 protein
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein]; pepstatin inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein]
SNCA protein inhibits the reaction [manganese chloride results in increased activity of CASP9 protein]
PRNP protein inhibits the reaction [manganese chloride results in increased activity of CASP9 protein]
CTD PMID:16787641 PMID:17483122 PMID:21704098 PMID:25416158 PMID:28378122 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase decreases activity
decreases expression
multiple interactions
EXP
ISO
manganese chloride results in decreased activity of CAT protein
manganese chloride results in decreased expression of CAT protein
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in decreased activity of CAT protein]; [manganese chloride results in increased abundance of Manganese] which results in decreased activity of CAT protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased activity of CAT protein]; Quercetin inhibits the reaction [manganese chloride results in decreased activity of CAT protein]; Silymarin inhibits the reaction [manganese chloride results in decreased activity of CAT protein]
[manganese chloride results in increased abundance of Manganese] which results in decreased activity of CAT protein; [Plant Extracts co-treated with manganese chloride] results in increased expression of CAT protein; Estradiol inhibits the reaction [manganese chloride results in decreased expression of CAT protein]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of CAT protein]
CTD PMID:20503066 PMID:22033861 PMID:22192907 PMID:26064043 PMID:28040552 PMID:29183790 PMID:30844427 PMID:32445656 PMID:33314588 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Catip ciliogenesis associated TTC17 interacting protein increases expression EXP manganese chloride results in increased expression of CATIP mRNA CTD PMID:28801915 NCBI chr 9:81,644,239...81,652,045
Ensembl chr 9:81,644,355...81,651,989
JBrowse link
G Catsperd cation channel sperm associated auxiliary subunit delta increases expression EXP manganese chloride results in increased expression of CATSPERD mRNA CTD PMID:28801915 NCBI chr 9:10,390,307...10,428,666
Ensembl chr 9:10,390,308...10,427,746
JBrowse link
G Cav2 caveolin 2 decreases expression EXP manganese chloride results in decreased expression of CAV2 mRNA CTD PMID:28801915 NCBI chr 4:44,573,264...44,580,640
Ensembl chr 4:44,573,264...44,580,638
JBrowse link
G Cbarp CACN subunit beta associated regulatory protein increases expression EXP manganese chloride results in increased expression of DOS mRNA CTD PMID:28801915 NCBI chr 7:12,433,422...12,441,048
Ensembl chr 7:12,433,933...12,441,048
JBrowse link
G Cbs cystathionine beta synthase decreases expression EXP manganese chloride results in decreased expression of CBS mRNA CTD PMID:28801915 NCBI chr20:10,361,987...10,386,663
Ensembl chr20:10,361,988...10,386,751
JBrowse link
G Ccdc15 coiled-coil domain containing 15 increases expression EXP manganese chloride results in increased expression of CCDC15 mRNA CTD PMID:28801915 NCBI chr 8:39,759,077...39,830,235
Ensembl chr 8:39,762,035...39,830,306
JBrowse link
G Ccdc175 coiled-coil domain containing 175 increases expression EXP manganese chloride results in increased expression of CCDC175 mRNA CTD PMID:28801915 NCBI chr 6:94,849,910...94,933,175
Ensembl chr 6:94,849,989...94,932,806
JBrowse link
G Ccdc96 coiled-coil domain containing 96 increases expression EXP manganese chloride results in increased expression of CCDC96 mRNA CTD PMID:28801915 NCBI chr14:79,443,151...79,445,591
Ensembl chr14:79,443,543...79,445,471
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 increases expression EXP manganese chloride results in increased expression of CCL17 mRNA CTD PMID:28801915 NCBI chr19:10,619,220...10,620,671
Ensembl chr19:10,619,220...10,620,671
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 increases expression EXP manganese chloride results in increased expression of CCL19 mRNA CTD PMID:28801915 NCBI chr 5:58,181,025...58,182,969
Ensembl chr 5:58,181,026...58,183,017
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases secretion
ISO
EXP
manganese chloride inhibits the reaction [CCL2 protein results in increased expression of ICAM1 protein]; manganese chloride inhibits the reaction [Glucose results in increased secretion of CCL2 protein]
manganese chloride results in decreased secretion of CCL2 protein
CTD PMID:23329836 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression EXP manganese chloride results in increased expression of CCL5 mRNA CTD PMID:28801915 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO
EXP
manganese chloride results in increased expression of CCL7 mRNA CTD PMID:17175027 PMID:28801915 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression
increases methylation
ISO
EXP
manganese chloride results in increased expression of CCN2 mRNA
manganese chloride results in increased methylation of CCN2 gene
CTD PMID:17467022 PMID:28801915 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccna1 cyclin A1 increases expression EXP manganese chloride results in increased expression of CCNA1 mRNA CTD PMID:26745496 NCBI chr 2:144,456,689...144,503,570
Ensembl chr 2:144,458,153...144,467,912
JBrowse link
G Ccnb2 cyclin B2 decreases expression ISO manganese chloride results in decreased expression of CCNB2 mRNA CTD PMID:17175027 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Ccng1 cyclin G1 increases expression EXP manganese chloride results in increased expression of CCNG1 mRNA CTD PMID:28801915 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Cd28 Cd28 molecule multiple interactions ISO [manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein; manganese chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CD28 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein] CTD PMID:8662792 NCBI chr 9:67,546,408...67,573,858
Ensembl chr 9:67,546,408...67,571,871
JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression EXP manganese chloride results in increased expression of CD44 mRNA CTD PMID:28801915 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd48 Cd48 molecule increases expression ISO manganese chloride results in increased expression of CD48 mRNA CTD PMID:17175027 NCBI chr13:90,116,601...90,140,371
Ensembl chr13:90,116,843...90,140,371
JBrowse link
G Cd6 Cd6 molecule decreases expression EXP manganese chloride results in decreased expression of CD6 mRNA CTD PMID:28801915 NCBI chr 1:226,848,399...226,887,259
Ensembl chr 1:226,848,403...226,887,156
JBrowse link
G Cd74 CD74 molecule increases expression EXP manganese chloride results in increased expression of CD74 mRNA CTD PMID:28801915 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Cd86 CD86 molecule increases expression ISO manganese chloride results in increased expression of CD86 protein CTD PMID:15737199 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cd8b CD8b molecule increases expression ISO manganese chloride results in increased expression of CD8B mRNA; manganese chloride results in increased expression of CD8B1 mRNA CTD PMID:17175027 NCBI chr 4:99,185,960...99,201,887
Ensembl chr 4:99,185,885...99,202,023
JBrowse link
G Cdc42ep3 CDC42 effector protein 3 increases expression EXP manganese chloride results in increased expression of CDC42EP3 mRNA CTD PMID:28801915 NCBI chr 6:1,922,500...1,942,972
Ensembl chr 6:1,922,500...1,942,972
JBrowse link
G Cdhr4 cadherin-related family member 4 decreases expression EXP manganese chloride results in decreased expression of CDHR4 mRNA CTD PMID:28801915 NCBI chr 8:116,771,377...116,779,242 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
affects localization
increases expression
EXP Cycloheximide inhibits the reaction [manganese chloride results in increased expression of CDKN1A protein]
manganese chloride affects the localization of CDKN1A protein
manganese chloride results in increased expression of CDKN1A mRNA; manganese chloride results in increased expression of CDKN1A protein
CTD PMID:22542671 PMID:28801915 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression EXP manganese chloride results in decreased expression of CDKN1C mRNA CTD PMID:28801915 NCBI chr 1:216,661,067...216,663,791
Ensembl chr 1:216,661,080...216,663,721
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B increases expression EXP manganese chloride results in increased expression of CDKN2B mRNA CTD PMID:28801915 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C decreases expression ISO manganese chloride results in decreased expression of CDKN2C mRNA CTD PMID:17175027 NCBI chr 5:129,347,731...129,352,886
Ensembl chr 5:129,347,732...129,352,886
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO manganese chloride results in decreased expression of CDKN3 mRNA CTD PMID:17175027 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
JBrowse link
G Cdnf cerebral dopamine neurotrophic factor increases expression EXP manganese chloride results in increased expression of CDNF mRNA CTD PMID:28801915 NCBI chr17:78,721,230...78,735,324
Ensembl chr17:78,719,111...78,735,324
JBrowse link
G Cdyl2 chromodomain Y-like 2 increases expression EXP manganese chloride results in increased expression of CDYL2 mRNA CTD PMID:28801915 NCBI chr19:49,087,131...49,222,528
Ensembl chr19:49,093,355...49,198,073
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO manganese chloride results in increased expression of CEBPD mRNA CTD PMID:17175027 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Celsr1 cadherin, EGF LAG seven-pass G-type receptor 1 increases expression ISO manganese chloride results in increased expression of CELSR1 mRNA CTD PMID:17175027 NCBI chr 7:126,774,010...126,914,085
Ensembl chr 7:126,775,516...126,913,585
JBrowse link
G Cep112 centrosomal protein 112 increases expression EXP manganese chloride results in increased expression of CEP112 mRNA CTD PMID:28801915 NCBI chr10:96,660,294...97,146,426
Ensembl chr10:96,663,740...97,146,424
JBrowse link
G Cep128 centrosomal protein 128 decreases expression ISO manganese chloride results in decreased expression of CEP128 mRNA CTD PMID:17175027 NCBI chr 6:114,759,474...115,158,004
Ensembl chr 6:114,759,474...115,157,854
JBrowse link
G Cers1 ceramide synthase 1 increases expression EXP manganese chloride results in increased expression of CERS1 mRNA CTD PMID:28801915 NCBI chr16:20,845,580...20,860,789
Ensembl chr16:20,845,576...20,860,789
JBrowse link
G Cers6 ceramide synthase 6 increases expression EXP manganese chloride results in increased expression of CERS6 mRNA CTD PMID:28801915 NCBI chr 3:55,094,240...55,338,370
Ensembl chr 3:55,094,637...55,338,445
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression EXP manganese chloride results in increased expression of CFLAR mRNA CTD PMID:28801915 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Cftr CF transmembrane conductance regulator increases expression EXP manganese chloride results in increased expression of CFTR mRNA CTD PMID:28801915 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 increases expression EXP manganese chloride results in increased expression of CGREF1 mRNA CTD PMID:28801915 NCBI chr 6:26,797,126...26,809,132
Ensembl chr 6:26,797,126...26,809,129
JBrowse link
G Ch25h cholesterol 25-hydroxylase increases expression EXP manganese chloride results in increased expression of CH25H mRNA CTD PMID:28801915 NCBI chr 1:252,807,062...252,811,409
Ensembl chr 1:252,807,065...252,808,380
JBrowse link
G Chat choline O-acetyltransferase multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased activity of CHAT protein CTD PMID:30738988 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Chml CHM like Rab escort protein increases expression EXP manganese chloride results in increased expression of CHML mRNA CTD PMID:28801915 NCBI chr13:93,740,759...93,742,624 JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit decreases expression ISO manganese chloride results in decreased expression of CHRNA7 protein CTD PMID:25874029 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196
JBrowse link
G Chst10 carbohydrate sulfotransferase 10 increases expression EXP manganese chloride results in increased expression of CHST10 mRNA CTD PMID:28801915 NCBI chr 9:45,528,928...45,559,365
Ensembl chr 9:45,528,928...45,559,140
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions
increases phosphorylation
EXP 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride results in increased phosphorylation of CHUK protein] CTD PMID:22245093 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator increases expression EXP manganese chloride results in increased expression of CIITA mRNA CTD PMID:28801915 NCBI chr10:5,212,621...5,260,641
Ensembl chr10:5,213,350...5,260,608
JBrowse link
G Cish cytokine inducible SH2-containing protein increases expression EXP manganese chloride results in increased expression of CISH mRNA CTD PMID:28801915 NCBI chr 8:116,054,547...116,059,494
Ensembl chr 8:116,054,465...116,060,723
JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 decreases expression EXP manganese chloride results in decreased expression of CITED1 mRNA CTD PMID:28801915 NCBI chr  X:72,128,996...72,133,692
Ensembl chr  X:72,128,994...72,133,692
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression ISO manganese chloride results in decreased expression of CKS2 mRNA CTD PMID:17175027 NCBI chr17:13,587,664...13,593,423
Ensembl chr17:13,587,665...13,593,423
JBrowse link
G Cldn23 claudin 23 increases expression EXP manganese chloride results in increased expression of CLDN23 mRNA CTD PMID:26745496 NCBI chr16:59,988,603...59,990,327
Ensembl chr16:59,988,603...59,990,326
JBrowse link
G Cldn4 claudin 4 increases expression EXP manganese chloride results in increased expression of CLDN4 mRNA CTD PMID:28801915 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005
JBrowse link
G Cldn9 claudin 9 decreases expression EXP manganese chloride results in decreased expression of CLDN9 mRNA CTD PMID:28801915 NCBI chr10:13,003,010...13,004,441
Ensembl chr10:13,003,011...13,004,441
JBrowse link
G Clec4f C-type lectin domain family 4, member F increases methylation EXP manganese chloride results in increased methylation of CLEC4F gene CTD PMID:28801915 NCBI chr 4:115,322,300...115,332,021
Ensembl chr 4:115,322,291...115,332,052
JBrowse link
G Clock clock circadian regulator decreases expression EXP manganese chloride results in decreased expression of CLOCK mRNA CTD PMID:28511934 NCBI chr14:34,418,226...34,502,218
Ensembl chr14:34,446,616...34,502,218
JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 increases expression
increases methylation
EXP manganese chloride results in increased expression of CMPK2 mRNA
manganese chloride results in increased methylation of CMPK2 gene
CTD PMID:28801915 NCBI chr 6:45,683,242...45,694,824
Ensembl chr 6:45,683,234...45,694,822
JBrowse link
G Cnksr1 connector enhancer of kinase suppressor of Ras 1 increases expression EXP manganese chloride results in increased expression of CNKSR1 mRNA CTD PMID:28801915 NCBI chr 5:152,447,348...152,458,005
Ensembl chr 5:152,446,845...152,458,023
JBrowse link
G Cnot2 CCR4-NOT transcription complex, subunit 2 decreases expression ISO manganese chloride results in decreased expression of CNOT2 mRNA CTD PMID:17175027 NCBI chr 7:59,526,105...59,617,307
Ensembl chr 7:59,527,124...59,587,385
JBrowse link
G Cnot6l CCR4-NOT transcription complex, subunit 6-like increases expression ISO manganese chloride results in increased expression of CNOT6L mRNA CTD PMID:17175027 NCBI chr14:15,059,101...15,148,255
Ensembl chr14:15,059,387...15,146,586
JBrowse link
G Cntn4 contactin 4 decreases expression ISO manganese chloride results in decreased expression of CNTN4 mRNA CTD PMID:15295902 NCBI chr 4:137,785,166...138,787,527
Ensembl chr 4:138,269,142...138,787,525
JBrowse link
G Col12a1 collagen type XII alpha 1 chain decreases expression ISO manganese chloride results in decreased expression of COL12A1 mRNA CTD PMID:17175027 NCBI chr 8:87,042,820...87,150,701
Ensembl chr 8:87,040,799...87,158,368
JBrowse link
G Col15a1 collagen type XV alpha 1 chain increases expression EXP manganese chloride results in increased expression of COL15A1 mRNA CTD PMID:28801915 NCBI chr 5:62,840,360...62,950,240
Ensembl chr 5:64,476,317...64,542,645
Ensembl chr 5:64,476,317...64,542,645
JBrowse link
G Col17a1 collagen type XVII alpha 1 chain increases expression EXP manganese chloride results in increased expression of COL17A1 mRNA CTD PMID:28801915 NCBI chr 1:267,416,681...267,465,049
Ensembl chr 1:267,417,459...267,463,705
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain increases expression ISO manganese chloride results in increased expression of COL18A1 mRNA CTD PMID:17467022 NCBI chr20:12,225,202...12,332,858
Ensembl chr20:12,225,202...12,332,858
JBrowse link
G Col4a5 collagen type IV alpha 5 chain decreases expression EXP manganese chloride results in decreased expression of COL4A5 mRNA CTD PMID:28801915 NCBI chr  X:112,769,595...112,983,720
Ensembl chr  X:112,769,645...112,983,685
JBrowse link
G Col5a2 collagen type V alpha 2 chain increases expression EXP manganese chloride results in increased expression of COL5A2 mRNA CTD PMID:28801915 NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564
JBrowse link
G Col6a1 collagen type VI alpha 1 chain increases expression EXP manganese chloride results in increased expression of COL6A1 mRNA CTD PMID:28801915 NCBI chr20:12,657,913...12,676,370
Ensembl chr20:12,658,065...12,675,561
JBrowse link
G Col7a1 collagen type VII alpha 1 chain increases expression EXP manganese chloride results in increased expression of COL7A1 mRNA CTD PMID:28801915 NCBI chr 8:117,694,441...117,726,844
Ensembl chr 8:117,694,605...117,726,844
JBrowse link
G Col8a1 collagen type VIII alpha 1 chain increases expression EXP manganese chloride results in increased expression of COL8A1 mRNA CTD PMID:28801915 NCBI chr11:44,877,690...45,006,203
Ensembl chr11:44,877,859...45,007,891
JBrowse link
G Colec10 collectin subfamily member 10 decreases expression EXP manganese chloride results in decreased expression of COLEC10 mRNA CTD PMID:28801915 NCBI chr 7:93,975,451...94,035,999
Ensembl chr 7:93,975,451...94,035,999
JBrowse link
G Colec12 collectin sub-family member 12 decreases expression EXP manganese chloride results in decreased expression of COLEC12 mRNA CTD PMID:28801915 NCBI chr18:867,048...1,054,047
Ensembl chr18:867,048...1,052,606
JBrowse link
G Copg2 COPI coat complex subunit gamma 2 increases expression EXP manganese chloride results in increased expression of COPG2 mRNA CTD PMID:28801915 NCBI chr 4:58,064,394...58,195,242
Ensembl chr 4:58,064,833...58,195,143
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 increases expression EXP manganese chloride results in increased expression of COX6A2 mRNA CTD PMID:28801915 NCBI chr 1:199,624,037...199,626,255
Ensembl chr 1:199,624,037...199,624,783
JBrowse link
G Cplx2 complexin 2 increases expression EXP manganese chloride results in increased expression of CPLX2 mRNA CTD PMID:28801915 NCBI chr17:10,756,871...10,828,811
Ensembl chr17:10,756,285...10,818,835
JBrowse link
G Cpm carboxypeptidase M decreases expression ISO manganese chloride results in decreased expression of CPM mRNA CTD PMID:17175027 NCBI chr 7:60,654,350...60,714,620
Ensembl chr 7:60,654,350...60,714,620
JBrowse link
G Cracdl CRACD like increases expression EXP manganese chloride results in increased expression of CRACDL mRNA CTD PMID:28801915 NCBI chr 9:44,194,348...44,309,816
Ensembl chr 9:44,194,325...44,237,117
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation
multiple interactions
EXP
ISO
manganese chloride results in increased phosphorylation of CREB1 protein
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of CREB1 protein; NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of CREB1 protein]
[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of CREB1 protein; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of CREB1 protein]
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein; CREB1 protein affects the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BDNF mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein]; SB 203580 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein]; SB 203580 inhibits the reaction [manganese chloride results in increased phosphorylation of CREB1 protein]
CTD PMID:16787641 PMID:30951808 PMID:31676349 PMID:32659473 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crebl2 cAMP responsive element binding protein-like 2 increases expression EXP manganese chloride results in increased expression of CREBL2 mRNA CTD PMID:28801915 NCBI chr 4:168,599,387...168,625,239
Ensembl chr 4:168,599,331...168,619,764
JBrowse link
G Crk CRK proto-oncogene, adaptor protein increases expression EXP manganese chloride results in increased expression of CRK mRNA CTD PMID:28801915 NCBI chr10:63,829,731...63,855,999
Ensembl chr10:63,829,807...63,852,780
JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression EXP manganese chloride results in decreased expression of CRY1 mRNA CTD PMID:28511934 NCBI chr 7:24,534,593...24,634,098
Ensembl chr 7:24,534,615...24,634,097
JBrowse link
G Cryaa crystallin, alpha A increases methylation EXP manganese chloride results in increased methylation of CRYAA gene CTD PMID:28801915 NCBI chr20:10,438,444...10,442,189
Ensembl chr20:10,438,444...10,442,187
JBrowse link
G Cryab crystallin, alpha B decreases expression EXP manganese chloride results in decreased expression of CRYAB mRNA CTD PMID:28801915 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Cryba4 crystallin, beta A4 increases expression EXP manganese chloride results in increased expression of CRYBA4 mRNA CTD PMID:28801915 NCBI chr12:50,407,843...50,414,434
Ensembl chr12:50,407,843...50,414,432
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions
increases expression
ISO
EXP
manganese chloride promotes the reaction [SNCA protein results in increased expression of CSF2 mRNA]
manganese chloride results in increased expression of CSF2 mRNA
CTD PMID:28539244 PMID:28801915 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csf3 colony stimulating factor 3 increases expression EXP manganese chloride results in increased expression of CSF3 mRNA CTD PMID:28801915 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 increases expression
increases methylation
EXP manganese chloride results in increased expression of CSPG4 mRNA
manganese chloride results in increased methylation of CSPG4 gene
CTD PMID:28801915 NCBI chr 8:61,532,465...61,567,510
Ensembl chr 8:61,532,465...61,567,510
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 increases expression EXP manganese chloride results in increased expression of CSRP3 mRNA CTD PMID:26745496 NCBI chr 1:104,147,205...104,166,389
Ensembl chr 1:104,147,206...104,166,367
JBrowse link
G Cstf2 cleavage stimulation factor subunit 2 increases expression EXP manganese chloride results in increased expression of CSTF2 mRNA CTD PMID:28801915 NCBI chr  X:104,882,726...104,909,746
Ensembl chr  X:104,882,704...104,909,739
JBrowse link
G Ctnna1 catenin alpha 1 decreases expression ISO manganese chloride results in decreased expression of CTNNA1 mRNA CTD PMID:17175027 NCBI chr18:27,923,229...28,055,972
Ensembl chr18:27,923,572...28,055,960
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression
multiple interactions
ISO
EXP
manganese chloride results in decreased expression of CTNNB1 mRNA
manganese chloride results in decreased expression of CTNNB1 protein
Lithium Chloride inhibits the reaction [manganese chloride results in decreased expression of CTNNB1 protein]
CTD PMID:17175027 PMID:24464479 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctnnd1 catenin delta 1 increases expression EXP manganese chloride results in increased expression of CTNND1 mRNA CTD PMID:28801915 NCBI chr 3:72,001,904...72,053,047
Ensembl chr 3:72,002,152...72,053,049
JBrowse link
G Ctsd cathepsin D increases expression
affects localization
EXP manganese chloride results in increased expression of CTSD protein
manganese chloride affects the localization of CTSD protein
CTD PMID:28378122 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Ctsw cathepsin W increases expression EXP manganese chloride results in increased expression of CTSW mRNA CTD PMID:28801915 NCBI chr 1:220,844,579...220,847,967
Ensembl chr 1:220,844,558...220,848,153
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression EXP manganese chloride results in increased expression of CX3CL1 mRNA CTD PMID:28801915 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases methylation
increases expression
EXP manganese chloride results in increased methylation of CXCL1 gene
manganese chloride results in increased expression of CXCL1 mRNA
CTD PMID:28801915 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO manganese chloride results in increased expression of CXCL10 mRNA CTD PMID:27427241 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression EXP manganese chloride results in decreased expression of CXCL12 mRNA CTD PMID:28801915 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 increases expression ISO manganese chloride results in increased expression of CXCL14 mRNA CTD PMID:17175027 NCBI chr17:9,109,731...9,117,754
Ensembl chr17:9,109,731...9,117,750
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO
EXP
manganese chloride results in increased expression of CXCL2 mRNA CTD PMID:17175027 PMID:28801915 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression EXP manganese chloride results in increased expression of CXCL3 mRNA CTD PMID:28801915 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 increases expression ISO manganese chloride results in increased expression of CXCL6 mRNA CTD PMID:17175027 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
JBrowse link
G Cxxc1 CXXC finger protein 1 increases methylation
decreases expression
ISO manganese chloride results in increased methylation of CXXC1 gene
manganese chloride results in decreased expression of CXXC1 mRNA
CTD PMID:27913844 NCBI chr18:70,192,520...70,197,871
Ensembl chr18:70,192,493...70,197,867
JBrowse link
G Cycs cytochrome c, somatic multiple interactions
affects localization
ISO BNIP3 protein affects the reaction [manganese chloride affects the localization of CYCS protein]; Cyclosporine inhibits the reaction [manganese chloride affects the localization of CYCS protein]
SNCA protein inhibits the reaction [manganese chloride affects the localization of CYCS protein]
CTD PMID:19442826 PMID:25416158 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
increases expression
decreases expression
EXP manganese chloride inhibits the reaction [CYP11A1 protein results in increased chemical synthesis of Progesterone]
manganese chloride results in increased expression of CYP11A1 mRNA
manganese chloride results in decreased expression of CYP11A1 protein
CTD PMID:12699903 PMID:25981801 PMID:28801915 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases expression EXP manganese chloride results in decreased expression of CYP26B1 mRNA CTD PMID:26745496 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615
JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 increases methylation
decreases expression
EXP manganese chloride results in increased methylation of CYP4F4 gene
manganese chloride results in decreased expression of CYP4F4 mRNA
CTD PMID:28801915 NCBI chr 7:14,891,062...14,907,250
Ensembl chr 7:14,891,001...14,907,305
JBrowse link
G Cyria CYFIP related Rac1 interactor A increases methylation
increases expression
EXP manganese chloride results in increased methylation of CYRIA gene
manganese chloride results in increased expression of CYRIA mRNA
CTD PMID:28801915 NCBI chr 6:37,555,167...37,661,196
Ensembl chr 6:37,555,182...37,665,064
JBrowse link
G Dach2 dachshund family transcription factor 2 increases expression ISO manganese chloride results in increased expression of DACH2 mRNA CTD PMID:17175027 NCBI chr  X:84,924,570...85,484,150
Ensembl chr  X:85,338,928...85,483,719
JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 decreases expression EXP manganese chloride results in decreased expression of DACT1 mRNA CTD PMID:28801915 NCBI chr 6:93,740,440...93,751,003
Ensembl chr 6:93,740,586...93,749,809
JBrowse link
G Dbh dopamine beta-hydroxylase increases methylation ISO manganese chloride results in increased methylation of DBH gene CTD PMID:27913844 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor increases expression EXP manganese chloride results in increased expression of DBP mRNA CTD PMID:28511934 NCBI chr 1:101,687,896...101,692,845
Ensembl chr 1:101,687,855...101,692,846
JBrowse link
G Dcp1b decapping mRNA 1B increases expression EXP manganese chloride results in increased expression of DCP1B mRNA CTD PMID:28801915 NCBI chr 4:151,249,654...151,287,018
Ensembl chr 4:151,250,041...151,285,702
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO
EXP
Deferoxamine promotes the reaction [manganese chloride results in increased expression of DDIT3 protein]
manganese chloride results in increased expression of DDIT3 mRNA; manganese chloride results in increased expression of DDIT3 protein
[manganese chloride results in increased abundance of Manganese] which results in increased expression of DDIT3 mRNA; SNCA protein promotes the reaction [manganese chloride results in increased expression of DDIT3 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of DDIT3 protein]
CTD PMID:23764342 PMID:23934647 PMID:23948121 PMID:25732873 PMID:32574669 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Defb29 defensin beta 29 increases methylation
increases expression
EXP manganese chloride results in increased methylation of DEFB29 gene
manganese chloride results in increased expression of DEFB29 mRNA
CTD PMID:28801915 NCBI chr 3:148,008,820...148,014,101
Ensembl chr 3:148,008,851...148,010,176
JBrowse link
G Depp1 DEPP1, autophagy regulator increases expression EXP manganese chloride results in increased expression of DEPP1 mRNA CTD PMID:28801915 NCBI chr 4:148,780,330...148,784,566
Ensembl chr 4:148,782,479...148,784,562
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 decreases expression EXP manganese chloride results in decreased expression of DHRS3 mRNA CTD PMID:28801915 NCBI chr 5:162,809,090...162,843,385
Ensembl chr 5:162,808,646...162,843,383
JBrowse link
G Dld dihydrolipoamide dehydrogenase decreases expression EXP manganese chloride results in decreased expression of DLD protein CTD PMID:25981801 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 increases methylation
decreases expression
ISO manganese chloride results in increased methylation of DLK1 gene
manganese chloride results in decreased expression of DLK1 mRNA
CTD PMID:27913844 NCBI chr 6:133,576,513...133,583,751
Ensembl chr 6:133,552,821...133,583,751
JBrowse link
G Dll4 delta like canonical Notch ligand 4 increases expression ISO manganese chloride results in increased expression of DLL4 mRNA CTD PMID:17467022 NCBI chr 3:111,135,011...111,146,746
Ensembl chr 3:111,135,021...111,145,986
JBrowse link
G Dmkn dermokine increases expression EXP manganese chloride results in increased expression of DMKN mRNA CTD PMID:28801915 NCBI chr 1:89,215,266...89,229,696
Ensembl chr 1:89,215,266...89,229,696
JBrowse link
G Dnah14 dynein axonemal heavy chain 14 decreases expression ISO manganese chloride results in decreased expression of DNAH14 mRNA CTD PMID:17175027 NCBI chr13:99,886,373...100,072,674
NCBI chr13:101,936,210...101,973,640
JBrowse link
G Dnai2 dynein, axonemal, intermediate chain 2 decreases expression EXP manganese chloride results in decreased expression of DNAI2 mRNA CTD PMID:28801915 NCBI chr10:103,266,343...103,301,521
Ensembl chr10:103,266,296...103,301,544
JBrowse link
G Dnajc12 DnaJ heat shock protein family (Hsp40) member C12 increases expression EXP manganese chloride results in increased expression of DNAJC12 mRNA CTD PMID:28801915 NCBI chr20:26,893,139...26,913,041
Ensembl chr20:26,893,016...26,913,016
JBrowse link
G Dnajc16 DnaJ heat shock protein family (Hsp40) member C16 increases expression EXP manganese chloride results in increased expression of DNAJC16 mRNA CTD PMID:28801915 NCBI chr 5:160,325,088...160,352,874
Ensembl chr 5:160,325,107...160,352,927
JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 decreases expression ISO manganese chloride results in decreased expression of DNPH1 mRNA CTD PMID:17175027 NCBI chr 9:16,845,764...16,848,514
Ensembl chr 9:16,845,525...16,848,503
JBrowse link
G Doc2a double C2 domain alpha increases expression EXP manganese chloride results in increased expression of DOC2A mRNA CTD PMID:28801915 NCBI chr 1:198,282,828...198,288,611
Ensembl chr 1:198,284,473...198,288,113
JBrowse link
G Dpep1 dipeptidase 1 decreases expression EXP manganese chloride results in decreased expression of DPEP1 mRNA CTD PMID:28801915 NCBI chr19:55,973,447...55,998,830
Ensembl chr19:55,982,740...55,998,208
JBrowse link
G Dpep2 dipeptidase 2 increases expression EXP manganese chloride results in increased expression of DPEP2 mRNA CTD PMID:28801915 NCBI chr19:37,964,098...37,975,154
Ensembl chr19:37,964,105...37,970,537
JBrowse link
G Dph1 diphthamide biosynthesis 1 increases expression EXP manganese chloride results in increased expression of DPH1 mRNA CTD PMID:28801915 NCBI chr10:62,019,379...62,032,384
Ensembl chr10:62,019,379...62,032,407
JBrowse link
G Dpp4 dipeptidylpeptidase 4 increases expression ISO manganese chloride results in increased expression of DPP4 mRNA CTD PMID:17175027 NCBI chr 3:48,291,055...48,372,672
Ensembl chr 3:48,291,055...48,372,672
JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 decreases expression
increases expression
ISO
EXP
manganese chloride results in decreased expression of DPYSL3 mRNA
manganese chloride results in increased expression of DPYSL3 mRNA
CTD PMID:22407947 PMID:25698507 PMID:28801915 NCBI chr18:37,716,371...37,819,347
Ensembl chr18:37,716,143...37,819,097
JBrowse link
G Dr1 down-regulator of transcription 1 decreases expression ISO manganese chloride results in decreased expression of DR1 mRNA CTD PMID:17175027 NCBI chr14:2,463,651...2,475,004
Ensembl chr14:2,463,643...2,474,780
Ensembl chr14:2,463,643...2,474,780
JBrowse link
G Drd1 dopamine receptor D1 decreases expression
multiple interactions
increases expression
ISO
EXP
manganese chloride results in decreased expression of DRD1 protein
[manganese chloride co-treated with Iron deficiency] results in decreased expression of DRD1 protein
manganese chloride results in increased expression of DRD1
Melatonin inhibits the reaction [manganese chloride results in decreased expression of DRD1 protein]
CTD PMID:22479410 PMID:23458069 PMID:23604964 PMID:24969583 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
decreases expression
increases expression
EXP
ISO
[manganese chloride co-treated with Iron deficiency] results in increased expression of DRD2 protein; manganese chloride inhibits the reaction [DRD2 protein binds to Spiperone]
Melatonin promotes the reaction [manganese chloride results in decreased expression of DRD2 protein]
manganese chloride results in increased expression of DRD2; manganese chloride results in increased expression of DRD2 protein; manganese chloride results in increased expression of DRD2 protein alternative form
CTD PMID:21484877 PMID:22479410 PMID:23458069 PMID:24969583 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Dscaml1 DS cell adhesion molecule-like 1 increases expression EXP manganese chloride results in increased expression of DSCAML1 mRNA CTD PMID:26745496 NCBI chr 8:49,733,835...50,056,115
Ensembl chr 8:49,737,798...50,055,560
JBrowse link
G Dspp dentin sialophosphoprotein increases expression ISO manganese chloride results in increased expression of DSPP mRNA CTD PMID:17175027 NCBI chr14:6,926,972...6,933,079
Ensembl chr14:6,926,976...6,933,070
JBrowse link
G Dtx1 deltex E3 ubiquitin ligase 1 increases expression EXP manganese chloride results in increased expression of DTX1 mRNA CTD PMID:28801915 NCBI chr12:41,383,885...41,415,783
Ensembl chr12:41,385,241...41,414,754
JBrowse link
G Dusp13 dual specificity phosphatase 13 increases expression EXP manganese chloride results in increased expression of DUSP13 mRNA CTD PMID:28801915 NCBI chr15:2,524,435...2,541,734
Ensembl chr15:2,526,368...2,541,729
Ensembl chr15:2,526,368...2,541,729
Ensembl chr15:2,526,368...2,541,729
Ensembl chr15:2,526,368...2,541,729
JBrowse link
G Dusp2 dual specificity phosphatase 2 increases expression EXP manganese chloride results in increased expression of DUSP2 mRNA CTD PMID:28801915 NCBI chr 3:119,776,925...119,779,110
Ensembl chr 3:119,776,925...119,779,099
JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression EXP manganese chloride results in increased expression of DUSP4 mRNA CTD PMID:28801915 NCBI chr16:61,080,767...61,090,973
Ensembl chr16:61,078,175...61,091,169
JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression
increases methylation
EXP manganese chloride results in increased expression of DUSP5 mRNA
manganese chloride results in increased methylation of DUSP5 gene
CTD PMID:28801915 NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595
JBrowse link
G Dusp6 dual specificity phosphatase 6 increases methylation
increases expression
EXP manganese chloride results in increased methylation of DUSP6 gene
manganese chloride results in increased expression of DUSP6 mRNA
CTD PMID:28801915 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Dynlt4 dynein light chain Tctex-type 4 increases expression EXP manganese chloride results in increased expression of DYNLT4 mRNA CTD PMID:28801915 NCBI chr 5:135,995,128...135,997,807
Ensembl chr 5:135,997,052...135,997,711
JBrowse link
G Eaf2 ELL associated factor 2 increases expression
increases methylation
EXP manganese chloride results in increased expression of EAF2 mRNA
manganese chloride results in increased methylation of EAF2 gene
CTD PMID:28801915 NCBI chr11:66,878,658...66,923,092
Ensembl chr11:66,878,658...66,923,092
JBrowse link
G Ebi3 Epstein-Barr virus induced 3 increases expression EXP manganese chloride results in increased expression of EBI3 mRNA CTD PMID:28801915 NCBI chr 9:11,110,874...11,114,843
Ensembl chr 9:11,110,874...11,114,843
JBrowse link
G Ecrg4 ECRG4 augurin precursor decreases expression EXP manganese chloride results in decreased expression of ECRG4 mRNA CTD PMID:28801915 NCBI chr 9:50,526,811...50,548,056
Ensembl chr 9:50,526,811...50,548,046
JBrowse link
G Edn1 endothelin 1 decreases expression EXP manganese chloride results in decreased expression of EDN1 mRNA CTD PMID:28801915 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Egf epidermal growth factor multiple interactions ISO [manganese chloride co-treated with EGF protein] results in increased activity of EGFR protein CTD PMID:2354210 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfl7 EGF-like-domain, multiple 7 increases expression ISO manganese chloride results in increased expression of EGFL7 mRNA CTD PMID:17467022 NCBI chr 3:4,034,759...4,044,280
Ensembl chr 3:4,034,921...4,043,936
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases expression
increases activity
ISO
EXP
[manganese chloride co-treated with EGF protein] results in increased activity of EGFR protein
manganese chloride results in increased expression of EGFR mRNA
manganese chloride results in increased activity of EGFR protein
CTD PMID:2354210 PMID:28801915 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 increases expression EXP manganese chloride results in increased expression of EGLN3 mRNA CTD PMID:28801915 NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795
JBrowse link
G Egr1 early growth response 1 increases expression EXP
ISO
manganese chloride results in increased expression of EGR1 mRNA CTD PMID:28801915 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Egr2 early growth response 2 increases expression ISO
EXP
manganese chloride results in increased expression of EGR2 mRNA CTD PMID:28801915 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Egr3 early growth response 3 increases expression EXP manganese chloride results in increased expression of EGR3 mRNA CTD PMID:28801915 NCBI chr15:51,756,683...51,762,080
Ensembl chr15:51,756,736...51,760,722
JBrowse link
G Eif1ad eukaryotic translation initiation factor 1A domain containing increases expression EXP manganese chloride results in increased expression of EIF1AD mRNA CTD PMID:28801915 NCBI chr 1:220,746,387...220,751,687
Ensembl chr 1:220,746,387...220,751,684
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A multiple interactions EXP manganese chloride results in increased expression of and results in increased phosphorylation of EIF2A protein; SNCA protein promotes the reaction [manganese chloride results in increased expression of and results in increased phosphorylation of EIF2A protein] CTD PMID:23934647 NCBI chr 2:148,722,343...148,755,781
Ensembl chr 2:148,722,231...148,755,520
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in increased cleavage of EIF2AK2 protein; GW 506033X inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of EIF2AK2 protein]; pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of EIF2AK2 protein] CTD PMID:32574669 NCBI chr 6:1,428,845...1,466,193
Ensembl chr 6:1,428,834...1,466,201
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases expression
increases phosphorylation
EXP [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of EIF2AK3 protein; manganese chloride promotes the reaction [EIF2AK3 protein results in increased expression of ATF4 mRNA]; manganese chloride promotes the reaction [EIF2AK3 protein results in increased phosphorylation of EIF2S1 protein]; manganese chloride results in increased expression of and results in increased phosphorylation of EIF2AK3 protein; SNCA protein promotes the reaction [manganese chloride results in increased expression of and results in increased phosphorylation of EIF2AK3 protein]
manganese chloride results in increased expression of EIF2AK3 protein
manganese chloride results in increased phosphorylation of EIF2AK3 protein
CTD PMID:23934647 PMID:23948121 PMID:25732873 PMID:32574669 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation
multiple interactions
ISO
EXP
manganese chloride results in increased phosphorylation of EIF2S1 protein
[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of EIF2S1 protein; manganese chloride promotes the reaction [EIF2AK3 protein results in increased phosphorylation of EIF2S1 protein]
CTD PMID:23764342 PMID:23948121 PMID:32574669 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
decreases phosphorylation
ISO corynoxine B promotes the reaction [manganese chloride results in decreased phosphorylation of EIF4EBP1 protein] CTD PMID:30578841 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Elf1 E74 like ETS transcription factor 1 decreases expression ISO manganese chloride results in decreased expression of ELF1 mRNA CTD PMID:17175027 NCBI chr15:61,772,544...61,868,442
Ensembl chr15:61,826,711...61,868,343
JBrowse link
G Elk3 ETS transcription factor ELK3 increases expression ISO manganese chloride results in increased expression of ELK3 mRNA CTD PMID:17467022 NCBI chr 7:34,086,213...34,149,601
Ensembl chr 7:34,086,220...34,121,694
JBrowse link
G Elmod3 ELMO domain containing 3 increases expression EXP manganese chloride results in increased expression of ELMOD3 mRNA CTD PMID:28801915 NCBI chr 4:100,422,256...100,465,152
Ensembl chr 4:100,422,252...100,465,112
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 decreases expression EXP manganese chloride results in decreased expression of ELOVL6 mRNA CTD PMID:28801915 NCBI chr 2:234,187,490...234,296,124
Ensembl chr 2:234,189,105...234,296,145
Ensembl chr 2:234,189,105...234,296,145
JBrowse link
G Eml2 EMAP like 2 increases expression ISO manganese chloride results in increased expression of EML2 mRNA CTD PMID:17175027 NCBI chr 1:80,087,684...80,118,784
Ensembl chr 1:80,087,684...80,119,012
JBrowse link
G Enc1 ectodermal-neural cortex 1 decreases expression EXP manganese chloride results in decreased expression of ENC1 mRNA CTD PMID:28801915 NCBI chr 2:28,049,217...28,061,023
Ensembl chr 2:28,049,217...28,061,029
JBrowse link
G Eng endoglin increases expression ISO manganese chloride results in increased expression of ENG mRNA CTD PMID:17467022 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Eno2 enolase 2 increases expression
multiple interactions
decreases expression
EXP
ISO
manganese chloride results in increased expression of ENO2 mRNA
Melatonin inhibits the reaction [manganese chloride results in decreased expression of ENO2 protein]
CTD PMID:22281203 PMID:24969583 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
Ensembl chr 9:157,285,179...157,294,047
JBrowse link
G Eomes eomesodermin decreases expression ISO manganese chloride results in decreased expression of EOMES mRNA; manganese chloride results in decreased expression of EOMES protein CTD PMID:25698507 NCBI chr 8:127,144,367...127,152,618
Ensembl chr 8:127,144,903...127,151,493
JBrowse link
G Epas1 endothelial PAS domain protein 1 increases expression ISO manganese chloride results in increased expression of EPAS1 mRNA CTD PMID:17467022 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Epdr1 ependymin related 1 increases expression EXP manganese chloride results in increased expression of EPDR1 mRNA CTD PMID:28801915 NCBI chr17:47,397,558...47,422,183
Ensembl chr17:47,397,558...47,422,182
JBrowse link
G Epha2 Eph receptor A2 increases expression EXP manganese chloride results in increased expression of EPHA2 mRNA CTD PMID:28801915 NCBI chr 5:159,845,773...159,874,203
Ensembl chr 5:159,845,774...159,874,206
JBrowse link
G Epha4 Eph receptor A4 increases methylation
decreases expression
EXP manganese chloride results in increased methylation of EPHA4 gene
manganese chloride results in decreased expression of EPHA4 mRNA
CTD PMID:28801915 NCBI chr 9:83,111,222...83,253,486
Ensembl chr 9:83,111,222...83,253,458
JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 increases expression ISO manganese chloride results in increased expression of ERAP1 mRNA CTD PMID:17467022 NCBI chr 2:1,410,877...1,449,734
Ensembl chr 2:1,410,934...1,449,733
JBrowse link
G Ercc6l ERCC excision repair 6 like, spindle assembly checkpoint helicase decreases expression ISO manganese chloride results in decreased expression of ERCC6L mRNA CTD PMID:17175027 NCBI chr  X:72,018,373...72,034,140
Ensembl chr  X:72,018,373...72,034,099
JBrowse link
G Ereg epiregulin increases expression ISO manganese chloride results in increased expression of EREG mRNA CTD PMID:17175027 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Erich1 glutamate-rich 1 increases expression ISO manganese chloride results in increased expression of ERICH1 mRNA CTD PMID:17175027 NCBI chr16:80,601,873...80,667,774
Ensembl chr16:80,601,973...80,667,781
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases phosphorylation
EXP SNCA protein promotes the reaction [manganese chloride results in increased phosphorylation of ERN1 protein] CTD PMID:23934647 PMID:25732873 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 increases expression EXP manganese chloride results in increased expression of ERRFI1 mRNA CTD PMID:28801915 NCBI chr 5:167,951,564...167,966,011
Ensembl chr 5:167,952,728...167,966,009
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases expression
ISO Estradiol inhibits the reaction [manganese chloride results in decreased expression of ESR1 protein]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of ESR1 protein] CTD PMID:29183790 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Etv3 ETS variant transcription factor 3 increases expression EXP manganese chloride results in increased expression of ETV3 mRNA CTD PMID:28801915 NCBI chr 2:186,872,483...186,887,294
Ensembl chr 2:186,872,520...186,886,592
JBrowse link
G Etv4 ETS variant transcription factor 4 increases expression EXP manganese chloride results in increased expression of ETV4 mRNA CTD PMID:28801915 NCBI chr10:89,685,058...89,700,300
Ensembl chr10:89,685,058...89,700,283
JBrowse link
G Etv5 ETS variant transcription factor 5 increases expression EXP manganese chloride results in increased expression of ETV5 mRNA CTD PMID:28801915 NCBI chr11:82,194,657...82,252,145
Ensembl chr11:82,194,657...82,252,139
JBrowse link
G Eva1c eva-1 homolog C increases expression EXP manganese chloride results in increased expression of EVA1C mRNA CTD PMID:28801915 NCBI chr11:31,001,697...31,075,784
Ensembl chr11:31,002,451...31,075,809
JBrowse link
G Exoc6 exocyst complex component 6 decreases expression ISO manganese chloride results in decreased expression of EXOC6 mRNA CTD PMID:17175027 NCBI chr 1:256,211,879...256,369,318
Ensembl chr 1:256,226,179...256,368,813
JBrowse link
G Eya4 EYA transcriptional coactivator and phosphatase 4 decreases expression ISO manganese chloride results in decreased expression of EYA4 mRNA CTD PMID:17175027 NCBI chr 1:23,237,617...23,611,580
Ensembl chr 1:23,409,408...23,610,164
JBrowse link
G F2rl1 F2R like trypsin receptor 1 increases expression EXP manganese chloride results in increased expression of F2RL1 mRNA CTD PMID:28801915 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G Fa2h fatty acid 2-hydroxylase increases expression
decreases expression
EXP manganese chloride results in increased expression of FA2H mRNA
manganese chloride results in decreased expression of FA2H mRNA
CTD PMID:26745496 PMID:28801915 NCBI chr19:43,545,380...43,596,788
Ensembl chr19:43,545,378...43,596,801
JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression EXP manganese chloride results in decreased expression of FADS2 mRNA CTD PMID:28801915 NCBI chr 1:225,906,582...226,152,568
Ensembl chr 1:226,114,413...226,152,524
JBrowse link
G Fam107a family with sequence similarity 107, member A decreases expression EXP manganese chloride results in decreased expression of FAM107A mRNA CTD PMID:26745496 NCBI chr15:18,399,145...18,415,959
Ensembl chr15:18,399,515...18,415,965
JBrowse link
G Fam171b family with sequence similarity 171, member B increases expression EXP manganese chloride results in increased expression of FAM171B mRNA CTD PMID:28801915 NCBI chr 3:71,210,048...71,265,419
Ensembl chr 3:71,210,301...71,262,615
JBrowse link
G Fam180a family with sequence similarity 180, member A decreases expression EXP manganese chloride results in decreased expression of FAM180A mRNA CTD PMID:26745496 NCBI chr 4:62,845,054...62,860,361
Ensembl chr 4:62,844,971...62,860,446
JBrowse link
G Fam210a family with sequence similarity 210, member A increases expression EXP manganese chloride results in increased expression of FAM210A mRNA CTD PMID:28801915 NCBI chr18:64,045,023...64,084,594
Ensembl chr18:64,045,432...64,084,556
JBrowse link
G Fam210b family with sequence similarity 210, member B increases expression EXP manganese chloride results in increased expression of FAM210B mRNA CTD PMID:28801915 NCBI chr 3:170,354,109...170,364,265
Ensembl chr 3:170,354,141...170,362,513
JBrowse link
G Fam219a family with sequence similarity 219, member A increases expression EXP manganese chloride results in increased expression of FAM219A mRNA CTD PMID:28801915 NCBI chr 5:57,896,824...57,947,569
Ensembl chr 5:57,897,368...57,947,183
JBrowse link
G Fam227a family with sequence similarity 227, member A increases expression EXP manganese chloride results in increased expression of FAM227A mRNA CTD PMID:28801915 NCBI chr 7:120,846,166...120,891,738
Ensembl chr 7:120,846,330...120,882,392
JBrowse link
G Fam229b family with sequence similarity 229, member B increases expression EXP manganese chloride results in increased expression of FAM229B mRNA CTD PMID:28801915 NCBI chr20:44,207,463...44,220,777
Ensembl chr20:44,207,478...44,220,702
JBrowse link
G Fam71f1 family with sequence similarity 71, member F1 increases expression EXP manganese chloride results in increased expression of FAM71F1 mRNA CTD PMID:28801915 NCBI chr 4:56,591,719...56,615,157
Ensembl chr 4:56,591,715...56,615,158
JBrowse link
G Fancf FA complementation group F decreases expression ISO manganese chloride results in decreased expression of FANCF mRNA CTD PMID:17175027 NCBI chr 1:107,229,516...107,232,321
Ensembl chr 1:107,231,292...107,232,305
JBrowse link
G Fas Fas cell surface death receptor increases expression EXP manganese chloride results in increased expression of FAS mRNA CTD PMID:28801915 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand increases expression
multiple interactions
EXP manganese chloride results in increased expression of FASLG protein
bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of FASLG protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased expression of FASLG protein]; pepstatin inhibits the reaction [manganese chloride results in increased expression of FASLG protein]
CTD PMID:21704098 PMID:28378122 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fasn fatty acid synthase decreases expression EXP manganese chloride results in decreased expression of FASN mRNA CTD PMID:28801915 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fat2 FAT atypical cadherin 2 increases methylation EXP manganese chloride results in increased methylation of FAT2 gene CTD PMID:28801915 NCBI chr10:40,583,025...40,682,598
Ensembl chr10:40,584,403...40,657,861
JBrowse link
G Fat4 FAT atypical cadherin 4 decreases expression EXP manganese chloride results in decreased expression of FAT4 mRNA CTD PMID:28801915 NCBI chr 2:125,751,818...125,879,398
Ensembl chr 2:125,752,130...125,879,387
Ensembl chr 2:125,752,130...125,879,387
JBrowse link
G Fbln2 fibulin 2 increases expression EXP manganese chloride results in increased expression of FBLN2 mRNA CTD PMID:28801915 NCBI chr 4:122,835,237...122,895,127
Ensembl chr 4:122,835,436...122,895,121
JBrowse link
G Fbn1 fibrillin 1 increases expression EXP manganese chloride results in increased expression of FBN1 mRNA CTD PMID:28801915 NCBI chr 3:117,569,708...117,766,160
Ensembl chr 3:117,569,697...117,766,120
JBrowse link
G Fbp2 fructose-bisphosphatase 2 increases expression EXP manganese chloride results in increased expression of FBP2 mRNA CTD PMID:28801915 NCBI chr17:372,554...389,918
Ensembl chr17:372,551...389,967
JBrowse link
G Fbxl2 F-box and leucine-rich repeat protein 2 increases expression EXP manganese chloride results in increased expression of FBXL2 mRNA CTD PMID:28801915 NCBI chr 8:122,240,393...122,290,439
Ensembl chr 8:122,243,016...122,311,431
JBrowse link
G Fbxl4 F-box and leucine-rich repeat protein 4 increases expression EXP manganese chloride results in increased expression of FBXL4 mRNA CTD PMID:28801915 NCBI chr 5:36,555,061...36,628,920
Ensembl chr 5:36,555,109...36,629,689
JBrowse link
G Fcgr1a Fc fragment of IgG receptor Ia decreases expression EXP manganese chloride results in decreased expression of FCGR1A mRNA CTD PMID:26745496 NCBI chr 2:198,430,536...198,439,453
Ensembl chr 2:198,430,530...198,458,041
JBrowse link
G Fcgr3a Fc fragment of IgG receptor IIIa increases expression EXP manganese chloride results in increased expression of FCGR3A mRNA CTD PMID:28801915 NCBI chr13:89,385,775...89,396,047
Ensembl chr13:89,385,859...89,396,051
JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression EXP manganese chloride results in decreased expression of FDPS mRNA CTD PMID:28801915 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 increases expression EXP manganese chloride results in increased expression of FEZ1 mRNA CTD PMID:28801915 NCBI chr 8:39,305,128...39,350,270
Ensembl chr 8:39,305,128...39,350,270
JBrowse link
G Fez2 fasciculation and elongation protein zeta 2 increases expression EXP manganese chloride results in increased expression of FEZ2 mRNA CTD PMID:28801915 NCBI chr 6:963,903...1,003,955
Ensembl chr 6:963,907...1,004,001
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression
increases methylation
ISO
EXP
manganese chloride results in decreased expression of FGF2 mRNA
manganese chloride results in increased methylation of FGF2 gene
CTD PMID:28801915 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgf20 fibroblast growth factor 20 increases expression ISO manganese chloride results in increased expression of FGF20 mRNA CTD PMID:28986288 NCBI chr16:55,152,748...55,159,352
Ensembl chr16:55,152,748...55,159,352
JBrowse link
G Fgfbp1 fibroblast growth factor binding protein 1 decreases expression EXP manganese chloride results in decreased expression of FGFBP1 mRNA CTD PMID:26745496 NCBI chr14:71,647,429...71,650,359
Ensembl chr14:71,649,274...71,650,354
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 decreases expression EXP manganese chloride results in decreased expression of FGFR2 mRNA CTD PMID:28801915 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
JBrowse link
G Fhip2b FHF complex subunit HOOK interacting protein 2B increases expression EXP manganese chloride results in increased expression of FHIP2B mRNA CTD PMID:28801915 NCBI chr15:52,271,495...52,288,938
Ensembl chr15:52,271,496...52,288,893
JBrowse link
G Fhl1 four and a half LIM domains 1 decreases expression ISO manganese chloride results in decreased expression of FHL1 mRNA CTD PMID:17175027 NCBI chr  X:159,112,516...159,172,528
Ensembl chr  X:159,112,880...159,172,524
JBrowse link
G Flcn folliculin increases expression ISO manganese chloride results in increased expression of FLCN mRNA CTD PMID:17175027 NCBI chr10:46,153,185...46,172,331
Ensembl chr10:46,153,188...46,172,309
JBrowse link
G Flrt2 fibronectin leucine rich transmembrane protein 2 increases expression EXP manganese chloride results in increased expression of FLRT2 mRNA CTD PMID:28801915 NCBI chr 6:119,518,459...119,613,534
Ensembl chr 6:119,519,714...119,609,296
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 increases expression ISO manganese chloride results in increased expression of FLT1 mRNA CTD PMID:17467022 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Flvcr2 FLVCR heme transporter 2 decreases expression EXP manganese chloride results in decreased expression of FLVCR2 mRNA CTD PMID:28801915 NCBI chr 6:109,617,348...109,681,495
Ensembl chr 6:109,617,355...109,681,495
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 increases expression EXP manganese chloride results in increased expression of FMO2 mRNA CTD PMID:28801915 NCBI chr13:80,752,526...80,775,264
Ensembl chr13:80,755,058...80,775,264
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 decreases methylation
increases expression
EXP manganese chloride results in decreased methylation of FMO5 gene
manganese chloride results in increased expression of FMO5 mRNA
CTD PMID:28801915 NCBI chr 2:199,796,870...199,823,927
Ensembl chr 2:199,796,881...199,823,927
JBrowse link
G Fn1 fibronectin 1 multiple interactions
increases expression
EXP [Buthionine Sulfoximine results in decreased abundance of Glutathione] promotes the reaction [manganese chloride results in increased expression of and results in increased secretion of FN1 protein]; [S-ethyl glutathione results in increased abundance of Glutathione] inhibits the reaction [manganese chloride results in increased expression of and results in increased secretion of FN1 protein]; [S-ethyl glutathione results in increased abundance of Glutathione] inhibits the reaction [manganese chloride results in increased expression of FN1 mRNA]; manganese chloride results in increased expression of and results in increased secretion of FN1 protein; Melatonin inhibits the reaction [manganese chloride results in increased expression of and results in increased secretion of FN1 protein]; Melatonin inhibits the reaction [manganese chloride results in increased expression of FN1 mRNA]; phenyl-N-tert-butylnitrone inhibits the reaction [manganese chloride results in increased expression of FN1 mRNA] CTD PMID:19524604 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
decreases expression
EXP
ISO
manganese chloride results in increased expression of FOS protein
manganese chloride results in decreased expression of FOS protein
CTD PMID:9751194 PMID:25698507 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression EXP manganese chloride results in increased expression of FOSL1 mRNA CTD PMID:28801915 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Foxn4 forkhead box N4 increases expression EXP manganese chloride results in increased expression of FOXN4 mRNA CTD PMID:26745496 NCBI chr12:48,101,012...48,121,281
Ensembl chr12:48,101,673...48,121,270
JBrowse link
G Foxp2 forkhead box P2 increases expression ISO manganese chloride results in increased expression of FOXP2 mRNA CTD PMID:17175027 NCBI chr 4:41,364,441...41,944,685
Ensembl chr 4:41,364,441...41,942,023
JBrowse link
G Frem3 FRAS1 related extracellular matrix 3 increases expression EXP manganese chloride results in increased expression of FREM3 mRNA CTD PMID:28801915 NCBI chr19:30,973,329...31,032,331
Ensembl chr19:30,973,329...31,031,817
JBrowse link
G Frmd4a FERM domain containing 4A increases expression EXP manganese chloride results in increased expression of FRMD4A mRNA CTD PMID:28801915 NCBI chr17:77,642,302...77,918,210 JBrowse link
G Fscn2 fascin actin-bundling protein 2, retinal decreases expression EXP manganese chloride results in decreased expression of FSCN2 mRNA CTD PMID:28801915 NCBI chr10:109,528,307...109,540,675
Ensembl chr10:109,533,487...109,540,026
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions
decreases expression
EXP Quercetin inhibits the reaction [manganese chloride results in decreased expression of FSHB protein] CTD PMID:28040552 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Fstl3 follistatin like 3 increases expression EXP manganese chloride results in increased expression of FSTL3 mRNA CTD PMID:28801915 NCBI chr 7:12,806,031...12,810,556
Ensembl chr 7:12,804,919...12,810,570
JBrowse link
G Fth1 ferritin heavy chain 1 decreases expression EXP manganese chloride results in decreased expression of FTH1 mRNA; manganese chloride results in decreased expression of FTH1 protein CTD PMID:15893546 PMID:15922012 PMID:16545456 PMID:16568477 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Ftl1 ferritin light chain 1 decreases expression EXP manganese chloride results in decreased expression of FTL mRNA CTD PMID:15893546 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Fut1 fucosyltransferase 1 increases expression EXP manganese chloride results in increased expression of FUT1 mRNA CTD PMID:28801915 NCBI chr 1:101,599,018...101,602,440
Ensembl chr 1:101,599,018...101,602,436
JBrowse link
G Fut2 fucosyltransferase 2 decreases expression
increases methylation
EXP manganese chloride results in decreased expression of FUT2 mRNA
manganese chloride results in increased methylation of FUT2 gene
CTD PMID:28801915 NCBI chr 1:101,631,633...101,651,668
Ensembl chr 1:101,631,635...101,651,668
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 increases expression ISO manganese chloride results in increased expression of FXYD2 mRNA CTD PMID:17175027 NCBI chr 8:49,710,334...49,717,492
Ensembl chr 8:49,710,477...49,716,955
JBrowse link
G G0s2 G0/G1switch 2 increases expression EXP manganese chloride results in increased expression of G0S2 mRNA CTD PMID:28801915 NCBI chr13:112,004,140...112,005,052
Ensembl chr13:112,004,140...112,005,052
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 multiple interactions
decreases expression
EXP
ISO
[Iron deficiency co-treated with manganese chloride] results in decreased expression of GABBR2 mRNA; [Iron deficiency co-treated with manganese chloride] results in decreased expression of GABBR2 protein
[manganese chloride results in increased abundance of Manganese] which results in increased expression of GABBR2 protein
manganese chloride results in decreased expression of GABBR2 mRNA
CTD PMID:18771689 PMID:32659473 NCBI chr 5:62,276,100...62,621,737
Ensembl chr 5:62,276,100...62,621,737
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions
increases expression
decreases expression
EXP
ISO
[Iron deficiency co-treated with manganese chloride] results in increased expression of GABRA1 protein
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of GABRA1 protein
manganese chloride results in increased expression of GABRA1 protein
manganese chloride results in decreased expression of GABRA1 mRNA
CTD PMID:18771689 PMID:32659473 NCBI chr10:27,310,718...27,371,802
Ensembl chr10:27,310,725...27,366,665
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 decreases expression EXP manganese chloride results in decreased expression of GABRB3 mRNA CTD PMID:28801915 NCBI chr 1:113,034,251...113,265,364
Ensembl chr 1:112,976,770...113,265,364
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 increases expression ISO manganese chloride results in increased expression of GABRG2 mRNA CTD PMID:17175027 NCBI chr10:27,090,913...27,179,786
Ensembl chr10:27,092,827...27,179,900
JBrowse link
G Gad1 glutamate decarboxylase 1 decreases expression EXP manganese chloride results in decreased expression of GAD1 mRNA CTD PMID:12106697 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression EXP manganese chloride results in decreased expression of GADD45A mRNA CTD PMID:28801915 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gal galanin and GMAP prepropeptide increases expression ISO manganese chloride results in increased expression of GAL mRNA CTD PMID:17175027 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
JBrowse link
G Gale UDP-galactose-4-epimerase decreases expression EXP manganese chloride results in decreased expression of GALE mRNA CTD PMID:28801915 NCBI chr 5:154,310,453...154,314,959
Ensembl chr 5:154,310,453...154,314,955
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 increases methylation
decreases expression
ISO manganese chloride results in increased methylation of GBE1 gene
manganese chloride results in decreased expression of GBE1 mRNA
CTD PMID:27913844 NCBI chr11:7,210,169...7,485,895
Ensembl chr11:7,210,209...7,485,890
JBrowse link
G Gbp5 guanylate binding protein 5 increases methylation
increases expression
EXP manganese chloride results in increased methylation of GBP5 gene
manganese chloride results in increased expression of GBP5 mRNA
CTD PMID:28801915 NCBI chr 2:248,178,441...248,196,873
Ensembl chr 2:248,178,389...248,197,160
JBrowse link
G Gcdh glutaryl-CoA dehydrogenase decreases expression EXP manganese chloride results in decreased expression of GCDH mRNA CTD PMID:22281203 NCBI chr19:26,000,497...26,006,970
Ensembl chr19:26,000,497...26,006,970
JBrowse link
G Gcfc2 GC-rich sequence DNA-binding factor 2 decreases expression ISO manganese chloride results in decreased expression of GCFC2 mRNA CTD PMID:17175027 NCBI chr 4:112,662,556...112,700,505
Ensembl chr 4:112,662,609...112,699,711
JBrowse link
G Gcgr glucagon receptor decreases expression
increases methylation
EXP manganese chloride results in decreased expression of GCGR mRNA
manganese chloride results in increased methylation of GCGR gene
CTD PMID:28801915 NCBI chr10:109,707,863...109,716,253
Ensembl chr10:109,707,962...109,716,128
JBrowse link
G Gch1 GTP cyclohydrolase 1 decreases expression EXP manganese chloride results in decreased expression of GCH1 mRNA CTD PMID:28801915 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Gdap2 ganglioside-induced differentiation-associated-protein 2 increases expression ISO manganese chloride results in increased expression of GDAP2 mRNA CTD PMID:17175027 NCBI chr 2:202,470,485...202,526,849
Ensembl chr 2:202,470,487...202,526,849
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO manganese chloride results in increased expression of GDF15 mRNA CTD PMID:17175027 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gdnf glial cell derived neurotrophic factor increases methylation ISO manganese chloride results in increased methylation of GDNF gene CTD PMID:27913844 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression
multiple interactions
increases expression
EXP
ISO
manganese chloride results in decreased expression of GFAP protein
Melatonin inhibits the reaction [manganese chloride results in increased expression of GFAP protein]
CTD PMID:12009774 PMID:12106697 PMID:24060432 PMID:24969583 PMID:25288107 PMID:28539244 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP manganese chloride results in decreased expression of GJA1 mRNA CTD PMID:28801915 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gja5 gap junction protein, alpha 5 decreases expression EXP manganese chloride results in decreased expression of GJA5 mRNA CTD PMID:26745496 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Gja8 gap junction protein, alpha 8 increases expression EXP manganese chloride results in increased expression of GJA8 mRNA CTD PMID:28801915 NCBI chr 2:199,050,854...199,052,470
Ensembl chr 2:199,050,854...199,052,470
JBrowse link
G Gjb5 gap junction protein, beta 5 increases expression EXP manganese chloride results in increased expression of GJB5 mRNA CTD PMID:28801915 NCBI chr 5:145,422,034...145,440,558
Ensembl chr 5:145,422,357...145,423,172
JBrowse link
G Gkn3 gastrokine 3 decreases expression EXP manganese chloride results in decreased expression of GKN3 mRNA CTD PMID:28801915 NCBI chr 4:119,181,970...119,188,356
Ensembl chr 4:119,182,135...119,188,251
JBrowse link
G Gldn gliomedin decreases expression EXP manganese chloride results in decreased expression of GLDN mRNA CTD PMID:26745496 NCBI chr 8:58,870,516...58,914,605
Ensembl chr 8:58,870,516...58,914,603
JBrowse link
G Glis1 GLIS family zinc finger 1 decreases expression EXP manganese chloride results in decreased expression of GLIS1 mRNA CTD PMID:28801915 NCBI chr 5:127,043,344...127,233,395
Ensembl chr 5:127,160,495...127,233,078
JBrowse link
G Glis2 GLIS family zinc finger 2 increases expression EXP manganese chloride results in increased expression of GLIS2 mRNA CTD PMID:28801915 NCBI chr10:11,154,459...11,177,063
Ensembl chr10:11,154,658...11,174,861
JBrowse link
G Glt8d2 glycosyltransferase 8 domain containing 2 increases expression EXP manganese chloride results in increased expression of GLT8D2 mRNA CTD PMID:28801915 NCBI chr 7:27,146,382...27,196,689
Ensembl chr 7:27,174,882...27,192,882
JBrowse link
G Glul glutamate-ammonia ligase decreases expression
multiple interactions
EXP manganese chloride results in decreased expression of GLUL mRNA; manganese chloride results in decreased expression of GLUL protein
Riluzole inhibits the reaction [manganese chloride results in decreased expression of and results in decreased activity of GLUL protein]; Riluzole inhibits the reaction [manganese chloride results in decreased expression of GLUL mRNA]
CTD PMID:19615351 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Gnb4 G protein subunit beta 4 increases expression EXP manganese chloride results in increased expression of GNB4 mRNA CTD PMID:28801915 NCBI chr 2:118,978,965...119,007,877
Ensembl chr 2:118,978,973...119,007,835
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 increases expression
increases secretion
multiple interactions
EXP manganese chloride results in increased expression of GNRH1 mRNA
manganese chloride results in increased secretion of GNRH1 protein
1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]; [manganese chloride co-treated with Calcium Chloride] results in increased secretion of GNRH1 protein; [manganese chloride results in increased chemical synthesis of Cyclic GMP] which results in increased secretion of GNRH1 protein; Bicuculline promotes the reaction [manganese chloride results in increased secretion of GNRH1 protein]; Dopamine affects the reaction [manganese chloride results in increased secretion of GNRH1 protein]; gamma-Aminobutyric Acid inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]; Haloperidol inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]; KT 5823 inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]; Methylene Blue inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]
CTD PMID:17110411 PMID:17290048 PMID:18603625 PMID:21402727 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875
JBrowse link
G Gpnmb glycoprotein nmb increases expression EXP manganese chloride results in increased expression of GPNMB mRNA CTD PMID:28801915 NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
JBrowse link
G Gpr18 G protein-coupled receptor 18 decreases expression EXP manganese chloride results in decreased expression of GPR18 mRNA CTD PMID:26745496 NCBI chr15:108,323,157...108,326,907
Ensembl chr15:108,323,179...108,326,907
JBrowse link
G Gpr34 G protein-coupled receptor 34 decreases expression EXP manganese chloride results in decreased expression of GPR34 mRNA CTD PMID:26745496 NCBI chr  X:10,022,986...10,043,504
Ensembl chr  X:10,023,489...10,031,167
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
decreases expression
ISO Melatonin affects the reaction [manganese chloride results in decreased expression of GPX1 protein] CTD PMID:24969583 PMID:25288107 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 increases methylation
decreases expression
ISO
EXP
manganese chloride results in increased methylation of GRIK3 gene
manganese chloride results in decreased expression of GRIK3 mRNA
CTD PMID:27913844 PMID:28801915 NCBI chr 5:143,500,441...143,715,546
Ensembl chr 5:143,500,441...143,715,546
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 decreases expression EXP manganese chloride results in decreased expression of GRIN1 mRNA; manganese chloride results in decreased expression of GRIN1 protein CTD PMID:20175136 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A decreases expression EXP manganese chloride results in decreased expression of GRIN2A mRNA; manganese chloride results in decreased expression of GRIN2A protein CTD PMID:20175136 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B decreases expression EXP manganese chloride results in decreased expression of GRIN2B mRNA; manganese chloride results in decreased expression of GRIN2B protein CTD PMID:20175136 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
decreases phosphorylation
increases activity
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in decreased phosphorylation of GSK3B protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased activity of GSK3B protein]; [Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; GSK3B protein affects the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; Lithium Chloride inhibits the reaction [manganese chloride results in decreased phosphorylation of and results in increased activity of GSK3B protein]; manganese chloride results in decreased phosphorylation of and results in increased activity of GSK3B protein CTD PMID:20937724 PMID:24464479 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gskip GSK3B interacting protein increases expression EXP manganese chloride results in increased expression of GSKIP mRNA CTD PMID:28801915 NCBI chr 6:129,512,950...129,536,320
Ensembl chr 6:129,519,709...129,536,221
JBrowse link
G Gspt2 G1 to S phase transition 2 decreases expression EXP manganese chloride results in decreased expression of GSPT2 mRNA CTD PMID:28801915 NCBI chr  X:63,959,131...63,961,652
Ensembl chr  X:63,954,727...63,961,613
JBrowse link
G Gsr glutathione-disulfide reductase decreases expression
multiple interactions
ISO manganese chloride results in decreased expression of GSR mRNA
[manganese chloride results in increased abundance of Manganese] which results in decreased activity of GSR protein; Melatonin affects the reaction [manganese chloride results in decreased expression of GSR protein]; Melatonin inhibits the reaction [manganese chloride results in decreased expression of GSR protein]
CTD PMID:17175027 PMID:24969583 PMID:25288107 PMID:32445656 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gtf2h1 general transcription factor IIH subunit 1 decreases expression ISO manganese chloride results in decreased expression of GTF2H1 mRNA CTD PMID:17175027 NCBI chr 1:102,849,618...102,877,939
Ensembl chr 1:102,849,889...102,877,944
JBrowse link
G H1f1 H1.1 linker histone, cluster member decreases expression EXP manganese chloride results in decreased expression of H1F1 mRNA CTD PMID:28801915 NCBI chr17:43,614,101...43,614,844
Ensembl chr17:43,614,101...43,614,844
JBrowse link
G H1f2 H1.2 linker histone, cluster member decreases expression EXP manganese chloride results in decreased expression of H1F2 mRNA CTD PMID:28801915 NCBI chr17:43,638,938...43,640,445
Ensembl chr17:43,639,749...43,640,387
JBrowse link
G H2bu1 H2B.U histone 1 decreases expression EXP manganese chloride results in decreased expression of H2BU1 mRNA CTD PMID:28801915 NCBI chr10:45,296,638...45,297,385
Ensembl chr10:45,296,638...45,297,385
JBrowse link
G H3c1 H3 clustered histone 1 decreases expression EXP manganese chloride results in decreased expression of H3C1 mRNA CTD PMID:28801915 NCBI chr17:43,616,206...43,616,735
Ensembl chr17:44,839,721...44,840,131
Ensembl chr17:44,839,721...44,840,131
Ensembl chr17:44,839,721...44,840,131
Ensembl chr17:44,839,721...44,840,131
JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression EXP manganese chloride results in decreased expression of HAMP mRNA CTD PMID:20635692 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Hapln3 hyaluronan and proteoglycan link protein 3 increases expression EXP manganese chloride results in increased expression of HAPLN3 mRNA CTD PMID:28801915 NCBI chr 1:140,827,279...140,845,386
Ensembl chr 1:140,827,295...140,835,151
JBrowse link
G Hat1 histone acetyltransferase 1 decreases expression EXP
ISO
manganese chloride results in decreased expression of HAT1 protein CTD PMID:29155171 NCBI chr 3:58,022,395...58,070,067
Ensembl chr 3:58,022,238...58,070,068
JBrowse link
G Hdac2 histone deacetylase 2 increases expression EXP manganese chloride results in increased expression of HDAC2 mRNA CTD PMID:29155171 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hdac3 histone deacetylase 3 increases expression ISO
EXP
manganese chloride results in increased expression of HDAC3 mRNA; manganese chloride results in increased expression of HDAC3 protein CTD PMID:29155171 NCBI chr18:31,073,057...31,094,347
Ensembl chr18:31,073,058...31,094,303
JBrowse link
G Hdac4 histone deacetylase 4 increases expression ISO
EXP
manganese chloride results in increased expression of HDAC4 mRNA; manganese chloride results in increased expression of HDAC4 protein CTD PMID:29155171 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715
JBrowse link
G Hdgfl3 HDGF like 3 increases expression EXP manganese chloride results in increased expression of HDGFL3 mRNA CTD PMID:28801915 NCBI chr 1:143,702,864...143,752,060
Ensembl chr 1:143,702,853...143,751,789
JBrowse link
G Heatr3 HEAT repeat containing 3 increases expression EXP manganese chloride results in increased expression of HEATR3 mRNA CTD PMID:28801915 NCBI chr19:19,858,419...19,896,782
Ensembl chr19:19,858,416...19,896,421
JBrowse link
G Heph hephaestin increases expression ISO manganese chloride results in increased expression of HEPH mRNA CTD PMID:17175027 NCBI chr  X:65,377,313...65,658,479
Ensembl chr  X:65,563,122...65,658,516
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 increases expression EXP manganese chloride results in increased expression of HEY1 mRNA CTD PMID:28801915 NCBI chr 2:95,320,147...95,322,701
Ensembl chr 2:95,320,283...95,322,696
JBrowse link
G Hfe homeostatic iron regulator multiple interactions
decreases response to substance
ISO HFE gene mutant form inhibits the reaction [manganese chloride results in decreased activity of SOD1 protein]
HFE gene mutant form results in decreased susceptibility to manganese chloride
CTD PMID:25874029 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
decreases expression
decreases degradation
increases stability
decreases hydroxylation
multiple interactions
ISO
EXP
manganese chloride results in increased expression of HIF1A mRNA; manganese chloride results in increased expression of HIF1A protein
manganese chloride results in decreased expression of HIF1A mRNA
manganese chloride results in decreased degradation of HIF1A protein
manganese chloride results in increased stability of HIF1A protein
manganese chloride results in decreased hydroxylation of HIF1A protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of HIF1A protein]; [manganese chloride results in decreased activity of P4HTM protein] which results in decreased degradation of HIF1A protein; [manganese chloride results in decreased activity of P4HTM protein] which results in decreased hydroxylation of HIF1A protein; Ascorbic Acid inhibits the reaction [manganese chloride results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [manganese chloride results in increased stability of HIF1A protein]; HIF1A mutant form inhibits the reaction [manganese chloride results in increased secretion of VEGFA protein]; Iron inhibits the reaction [manganese chloride results in increased expression of HIF1A protein]; manganese chloride inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]]; manganese chloride results in increased expression of and results in increased activity of and results in increased stability of HIF1A protein; pyrazolanthrone inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of and results in increased stability of HIF1A protein]; SB 203580 inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of and results in increased stability of HIF1A protein]; SB 203580 inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of HIF1A protein]; VHL protein affects the reaction [manganese chloride results in increased expression of HIF1A protein]
CTD PMID:17175027 PMID:17467022 PMID:19074761 PMID:19263519 PMID:20152896 PMID:28801915 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor decreases expression ISO manganese chloride results in decreased expression of HIF1AN mRNA CTD PMID:17175027 NCBI chr 1:264,309,214...264,319,269
Ensembl chr 1:264,309,214...264,319,267
JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated increases expression EXP manganese chloride results in increased expression of HILPDA mRNA CTD PMID:22281203 NCBI chr 4:56,547,600...56,550,584
Ensembl chr 4:56,549,739...56,549,993
JBrowse link
G Hipk3 homeodomain interacting protein kinase 3 decreases expression EXP manganese chloride results in decreased expression of HIPK3 mRNA CTD PMID:28801915 NCBI chr 3:94,349,778...94,419,185
Ensembl chr 3:94,352,969...94,419,048
JBrowse link
G Hist1h2an histone cluster 1, H2an decreases expression EXP manganese chloride results in decreased expression of HIST1H2AN mRNA CTD PMID:28801915 NCBI chr17:43,779,174...43,779,775
Ensembl chr17:44,520,537...44,520,929
Ensembl chr17:44,520,537...44,520,929
Ensembl chr17:44,520,537...44,520,929
Ensembl chr17:44,520,537...44,520,929
JBrowse link
G Hist1h2bc histone cluster 1, H2bc decreases expression EXP manganese chloride results in decreased expression of HIST1H2BC mRNA CTD PMID:28801915 NCBI chr17:44,736,184...44,738,393
Ensembl chr17:44,737,950...44,738,330
Ensembl chr17:44,737,950...44,738,330
JBrowse link
G Hist1h2bl histone cluster 1 H2B family member l decreases expression EXP manganese chloride results in decreased expression of HIST1H2BL mRNA CTD PMID:28801915 NCBI chr17:44,748,445...44,748,910
Ensembl chr17:44,748,482...44,748,862
JBrowse link
G Hist1h2bq histone cluster 1 H2B family member Q decreases expression EXP manganese chloride results in decreased expression of HIST1H2BQ mRNA CTD PMID:28801915 NCBI chr17:43,679,925...43,689,311
Ensembl chr17:43,679,925...43,689,311
JBrowse link
G Hist2h2aa2 histone cluster 2 H2A family member A2 decreases expression EXP manganese chloride results in decreased expression of HIST2H2AA2 mRNA CTD PMID:28801915 NCBI chr 2:198,381,678...198,382,247
Ensembl chr 2:198,388,809...198,389,201
Ensembl chr 2:198,388,809...198,389,201
JBrowse link
G Hist3h2ba histone cluster 3, H2ba decreases expression EXP manganese chloride results in decreased expression of HIST3H2BA mRNA CTD PMID:28801915 NCBI chr10:45,289,741...45,290,370
Ensembl chr10:45,289,741...45,290,370
JBrowse link
G Hmbox1 homeobox containing 1 decreases expression EXP manganese chloride results in decreased expression of HMBOX1 mRNA CTD PMID:28801915 NCBI chr15:48,194,709...48,326,310
Ensembl chr15:48,199,995...48,284,548
JBrowse link
G Hmcn2 hemicentin 2 increases expression EXP manganese chloride results in increased expression of HMCN2 mRNA CTD PMID:28801915 NCBI chr 3:10,384,873...10,536,529 JBrowse link
G Hmgb1 high mobility group box 1 increases expression
multiple interactions
ISO manganese chloride results in increased expression of HMGB1 mRNA
corynoxine B affects the reaction [manganese chloride affects the reaction [HMGB1 protein binds to BECN1 protein]]; corynoxine B inhibits the reaction [manganese chloride promotes the reaction [HMGB1 protein binds to SNCA protein]]; manganese chloride affects the reaction [HMGB1 protein binds to BECN1 protein]; manganese chloride promotes the reaction [HMGB1 protein binds to SNCA protein]; manganese chloride results in increased expression of and affects the localization of HMGB1 protein
CTD PMID:30578841 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 decreases expression EXP manganese chloride results in decreased expression of HMGCS2 mRNA CTD PMID:26745496 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hmox1 heme oxygenase 1 affects response to substance
increases expression
multiple interactions
ISO
EXP
HMOX1 protein affects the susceptibility to manganese chloride
manganese chloride results in increased expression of HMOX1 protein
manganese chloride results in increased expression of HMOX1 mRNA; manganese chloride results in increased expression of HMOX1 protein
HMOX1 protein inhibits the reaction [manganese chloride results in increased abundance of Hydrogen Peroxide]; manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 mRNA]; manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 protein]; Melatonin inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased expression of HMOX1 protein; anacardic acid promotes the reaction [manganese chloride results in increased expression of HMOX1 mRNA]; GW 506033X promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of HMOX1 protein]; lactacystin promotes the reaction [manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; lactacystin promotes the reaction [manganese chloride results in increased expression of HMOX1 protein]; manganese chloride promotes the reaction [[NFE2L2 protein binds to HMOX1 promoter] which results in increased expression of HMOX1 mRNA]; manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]; SB 203580 inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; tin protoporphyrin IX inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; trichostatin A promotes the reaction [manganese chloride results in increased expression of HMOX1 mRNA]; trichostatin A promotes the reaction [manganese chloride results in increased expression of HMOX1 protein]
CTD PMID:21107535 PMID:21384399 PMID:21963524 PMID:22281203 PMID:25288107 PMID:29054681 PMID:30040983 PMID:32574669 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hoxb9 homeo box B9 decreases expression ISO manganese chloride results in decreased expression of HOXB9 mRNA CTD PMID:17175027 NCBI chr10:84,119,772...84,124,963
Ensembl chr10:84,119,884...84,123,390
JBrowse link
G Hoxd4 homeo box D4 increases expression EXP manganese chloride results in increased expression of HOXD4 mRNA CTD PMID:28801915 NCBI chr 3:61,634,005...61,653,581
Ensembl chr 3:61,634,005...61,651,056
JBrowse link
G Hpx hemopexin decreases expression EXP manganese chloride results in decreased expression of HPX mRNA CTD PMID:28801915 NCBI chr 1:170,423,558...170,431,066
Ensembl chr 1:170,423,483...170,431,073
JBrowse link
G Hrh1 histamine receptor H 1 decreases methylation ISO manganese chloride results in decreased methylation of HRH1 gene CTD PMID:27913844 NCBI chr 4:146,374,596...146,458,148
Ensembl chr 4:146,455,332...146,457,074
JBrowse link
G Hrk harakiri, BCL2 interacting protein increases expression
decreases methylation
EXP manganese chloride results in increased expression of HRK mRNA
manganese chloride results in decreased methylation of HRK gene
CTD PMID:28801915 NCBI chr12:44,008,879...44,029,211 JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases expression EXP manganese chloride results in increased expression of HSD11B1 mRNA CTD PMID:28801915 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions
increases expression
EXP SNCA protein promotes the reaction [manganese chloride results in increased expression of HSP90B1 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of HSP90B1 protein]
manganese chloride results in increased expression of HSP90B1 mRNA; manganese chloride results in increased expression of HSP90B1 protein
CTD PMID:23934647 PMID:23948121 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like increases expression EXP manganese chloride results in increased expression of HSPA4L mRNA CTD PMID:28801915 NCBI chr 2:127,625,737...127,682,864
Ensembl chr 2:127,625,683...127,677,503
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
EXP [manganese chloride results in increased abundance of Manganese] which results in increased expression of HSPA5 mRNA; SNCA protein promotes the reaction [manganese chloride results in increased expression of HSPA5 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of HSPA5 protein]
manganese chloride results in increased expression of HSPA5 mRNA; manganese chloride results in increased expression of HSPA5 protein
CTD PMID:23934647 PMID:23948121 PMID:25732873 PMID:32574669 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspb8 heat shock protein family B (small) member 8 decreases expression EXP manganese chloride results in decreased expression of HSPB8 mRNA CTD PMID:28801915 NCBI chr12:45,905,371...45,920,014
Ensembl chr12:45,905,371...45,920,013
JBrowse link
G Htra1 HtrA serine peptidase 1 increases expression EXP manganese chloride results in increased expression of HTRA1 mRNA CTD PMID:28801915 NCBI chr 1:201,499,067...201,548,508
Ensembl chr 1:201,499,028...201,548,513
JBrowse link
G Htt huntingtin affects response to substance ISO HTT affects the susceptibility to manganese chloride CTD PMID:22363539 NCBI chr14:81,105,139...81,254,637
Ensembl chr14:81,105,139...81,254,637
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
decreases expression
ISO
EXP
manganese chloride inhibits the reaction [CCL2 protein results in increased expression of ICAM1 protein]; manganese chloride inhibits the reaction [Glucose results in increased expression of ICAM1 protein]
manganese chloride results in decreased expression of ICAM1 protein
CTD PMID:23329836 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO manganese chloride results in increased expression of ID1 mRNA CTD PMID:17467022 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression
decreases expression
ISO
EXP
manganese chloride results in increased expression of ID2 mRNA
manganese chloride results in decreased expression of ID2 mRNA
CTD PMID:17175027 PMID:28801915 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
EXP
ISO
manganese chloride results in increased expression of IFNG protein
manganese chloride promotes the reaction [[TNF protein co-treated with IFNG protein] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]]; manganese chloride promotes the reaction [TNF protein co-treated with and results in increased chemical synthesis of IFNG protein co-treated with and results in increased chemical synthesis of Nitric Oxide]; manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 mRNA]; manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 protein]; NFKBIA protein affects the reaction [manganese chloride promotes the reaction [TNF protein co-treated with and results in increased chemical synthesis of IFNG protein co-treated with and results in increased chemical synthesis of Nitric Oxide]]; NFKBIA protein affects the reaction [manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 mRNA]]; NFKBIA protein affects the reaction [manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 protein]]
CTD PMID:16168523 PMID:20798247 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression EXP manganese chloride results in increased expression of IGF1 mRNA CTD PMID:21402727 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression
decreases expression
EXP manganese chloride results in increased expression of IGF1R protein
manganese chloride results in decreased expression of IGF1R mRNA
CTD PMID:19276553 PMID:21402727 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igf2 insulin-like growth factor 2 decreases methylation ISO manganese chloride results in decreased methylation of IGF2 gene CTD PMID:27913844 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Igf2r insulin-like growth factor 2 receptor decreases expression EXP manganese chloride results in decreased expression of IGF2R mRNA CTD PMID:19276553 NCBI chr 1:48,176,095...48,264,482
Ensembl chr 1:48,176,106...48,264,477
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 increases expression EXP manganese chloride results in increased expression of IGFBP5 mRNA CTD PMID:28801915 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO IKBKB gene mutant form results in increased susceptibility to [manganese chloride results in increased abundance of Manganese] CTD PMID:32692843 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il12a interleukin 12A increases expression
multiple interactions
ISO manganese chloride results in increased expression of IL12A mRNA
manganese chloride promotes the reaction [SNCA protein results in increased expression of [IL12A protein binds to IL12B protein]]
manganese chloride results in increased expression of [IL12A protein binds to IL12B protein]
CTD PMID:17175027 PMID:28539244 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il12b interleukin 12B multiple interactions
increases expression
ISO manganese chloride promotes the reaction [SNCA protein results in increased expression of [IL12A protein binds to IL12B protein]]
manganese chloride results in increased expression of IL12B mRNA
manganese chloride results in increased expression of [IL12A protein binds to IL12B protein]
CTD PMID:28539244 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il18 interleukin 18 multiple interactions
increases expression
ISO acetovanillone analog inhibits the reaction [manganese chloride results in increased expression of IL18 mRNA] CTD PMID:28539244 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha increases expression EXP manganese chloride results in increased expression of IL1A mRNA CTD PMID:25219578 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
decreases expression
EXP
ISO
manganese chloride results in increased expression of IL1B protein
[manganese chloride co-treated with SNCA protein] results in increased expression of IL1B mRNA; [manganese chloride co-treated with SNCA protein] results in increased expression of IL1B protein
manganese chloride results in increased expression of IL1B mRNA
manganese chloride results in decreased expression of IL1B mRNA
[Lipopolysaccharides co-treated with manganese chloride] results in increased expression of IL1B protein; acetovanillone analog inhibits the reaction [manganese chloride results in increased expression of IL1B mRNA]
[manganese chloride results in increased abundance of Manganese] which results in increased expression of IL1B protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of IL1B protein]; Minocycline inhibits the reaction [manganese chloride results in increased expression of IL1B protein]
CTD PMID:15601679 PMID:18836210 PMID:27427241 PMID:28539244 PMID:33314588 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r1 interleukin 1 receptor type 1 increases expression EXP manganese chloride results in increased expression of IL1R1 mRNA CTD PMID:28801915 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Il1r2 interleukin 1 receptor type 2 increases expression EXP manganese chloride results in increased expression of IL1R2 mRNA CTD PMID:28801915 NCBI chr 9:46,840,646...46,881,241
Ensembl chr 9:46,840,992...46,881,264
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 decreases expression
increases expression
EXP manganese chloride results in decreased expression of IL1RL1 mRNA
manganese chloride results in increased expression of IL1RL1 mRNA
CTD PMID:26745496 PMID:28801915 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression EXP manganese chloride results in increased expression of IL1RN mRNA CTD PMID:28801915 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il23a interleukin 23 subunit alpha increases expression EXP manganese chloride results in increased expression of IL23A mRNA CTD PMID:28801915 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link
G Il36rn interleukin 36 receptor antagonist increases expression EXP manganese chloride results in increased expression of IL36RN mRNA CTD PMID:28801915 NCBI chr 3:1,385,256...1,392,275
Ensembl chr 3:1,385,654...1,392,275
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
increases secretion
decreases expression
ISO
EXP
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; Buthionine Sulfoximine inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; Lipopolysaccharides promotes the reaction [manganese chloride results in increased expression of IL6 protein]; manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]; manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein]; manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; tin protoporphyrin IX inhibits the reaction [manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; zinc protoporphyrin inhibits the reaction [manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein]]
manganese chloride results in increased expression of IL6 mRNA
manganese chloride promotes the reaction [SNCA protein results in increased expression of IL6 mRNA]
manganese chloride results in increased secretion of IL6 protein
manganese chloride results in decreased expression of IL6 mRNA
manganese chloride results in increased expression of IL6 mRNA; manganese chloride results in increased expression of IL6 protein
CTD PMID:15601679 PMID:17065364 PMID:19815061 PMID:21963524 PMID:25219578 PMID:27427241 PMID:28539244 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il7 interleukin 7 increases expression ISO manganese chloride results in increased expression of IL7 mRNA CTD PMID:17175027 NCBI chr 2:96,427,884...96,474,979
Ensembl chr 2:96,439,286...96,474,977
JBrowse link
G Ins2 insulin 2 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] inhibits the reaction [Glucose results in increased secretion of INS protein] CTD PMID:31555879 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Insig1 insulin induced gene 1 decreases expression
increases methylation
EXP manganese chloride results in decreased expression of INSIG1 mRNA
manganese chloride results in increased methylation of INSIG1 gene
CTD PMID:28801915 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Insr insulin receptor decreases expression
increases expression
increases phosphorylation
EXP manganese chloride results in decreased expression of INSR mRNA
manganese chloride results in increased expression of INSR mRNA
manganese chloride results in increased phosphorylation of INSR protein
CTD PMID:2475105 PMID:19276553 PMID:28801915 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Ints2 integrator complex subunit 2 decreases expression EXP manganese chloride results in decreased expression of INTS2 mRNA CTD PMID:28801915 NCBI chr10:73,632,805...73,690,952
Ensembl chr10:73,634,255...73,690,887
JBrowse link
G Iqcg IQ motif containing G increases expression EXP manganese chloride results in increased expression of IQCG mRNA CTD PMID:28801915 NCBI chr11:70,967,228...71,007,708
Ensembl chr11:70,967,223...71,105,403
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 increases expression EXP manganese chloride results in increased expression of IQGAP1 mRNA CTD PMID:28801915 NCBI chr 1:142,525,041...142,615,673
Ensembl chr 1:142,525,046...142,615,673
JBrowse link
G Ireb2 iron responsive element binding protein 2 decreases activity
increases activity
EXP manganese chloride results in decreased activity of IREB2 protein
manganese chloride results in increased activity of IREB2 protein
CTD PMID:15893546 PMID:16568477 NCBI chr 8:59,450,974...59,503,634
Ensembl chr 8:59,420,123...59,501,118
JBrowse link
G Irf2 interferon regulatory factor 2 decreases expression EXP manganese chloride results in decreased expression of IRF2 mRNA CTD PMID:28801915 NCBI chr16:48,582,354...48,732,129
Ensembl chr16:48,582,026...48,732,932
JBrowse link
G Ism1 isthmin 1 increases expression EXP manganese chloride results in increased expression of ISM1 mRNA CTD PMID:28801915 NCBI chr 3:132,736,433...132,808,544 JBrowse link
G Itga10 integrin subunit alpha 10 increases expression EXP manganese chloride results in increased expression of ITGA10 mRNA CTD PMID:28801915 NCBI chr 2:198,772,937...198,792,253
Ensembl chr 2:198,772,937...198,792,253
JBrowse link
G Itga2b integrin subunit alpha 2b multiple interactions ISO manganese chloride inhibits the reaction [TLN1 protein mutant form results in decreased activity of [ITGB3 protein binds to ITGA2B protein]]; manganese chloride results in increased activity of [ITGB3 protein binds to ITGA2B protein] CTD PMID:20971947 NCBI chr10:90,397,960...90,416,550
Ensembl chr10:90,398,132...90,415,070
JBrowse link
G Itga3 integrin subunit alpha 3 increases expression ISO manganese chloride results in increased expression of ITGA3 mRNA CTD PMID:17175027 NCBI chr10:82,855,841...82,887,755
Ensembl chr10:82,855,613...82,887,497
JBrowse link
G Itga8 integrin subunit alpha 8 increases expression
increases methylation
EXP manganese chloride results in increased expression of ITGA8 mRNA
manganese chloride results in increased methylation of ITGA8 gene
CTD PMID:28801915 NCBI chr17:79,321,893...79,676,927
Ensembl chr17:79,321,900...79,676,499
JBrowse link
G Itgam integrin subunit alpha M increases expression EXP manganese chloride results in increased expression of ITGAM protein CTD PMID:12106697 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Itgav integrin subunit alpha V multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; [AG 1879 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; [CGP 77675 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; arginyl-glycyl-aspartic acid inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]; wortmannin inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]] CTD PMID:15213856 NCBI chr 3:71,113,269...71,205,958
Ensembl chr 3:71,114,100...71,202,411
JBrowse link
G Itgb3 integrin subunit beta 3 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; [AG 1879 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; [CGP 77675 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; arginyl-glycyl-aspartic acid inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]; Wortmannin inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]
manganese chloride inhibits the reaction [TLN1 protein mutant form results in decreased activity of [ITGB3 protein binds to ITGA2B protein]]; manganese chloride results in increased activity of [ITGB3 protein binds to ITGA2B protein]
CTD PMID:15213856 PMID:20971947 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Itgb5 integrin subunit beta 5 increases expression ISO manganese chloride results in increased expression of ITGB5 mRNA CTD PMID:17175027 NCBI chr11:70,056,500...70,172,164
Ensembl chr11:70,056,500...70,172,372
JBrowse link
G Itgb6 integrin subunit beta 6 decreases methylation
increases expression
increases methylation
ISO
EXP
manganese chloride results in decreased methylation of ITGB6 gene
manganese chloride results in increased expression of ITGB6 mRNA
manganese chloride results in increased methylation of ITGB6 gene
CTD PMID:27913844 PMID:28801915 NCBI chr 3:46,652,624...46,775,362
Ensembl chr 3:46,652,623...46,726,958
JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 multiple interactions ISO manganese chloride promotes the reaction [ITIH1 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr16:7,012,376...7,026,542
Ensembl chr16:7,012,354...7,026,540
JBrowse link
G Itih2 inter-alpha-trypsin inhibitor heavy chain 2 multiple interactions ISO manganese chloride promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr17:72,160,734...72,197,248
Ensembl chr17:72,160,735...72,195,509
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases phosphorylation
EXP manganese chloride results in increased expression of and results in increased phosphorylation of JUN protein; pyrazolanthrone inhibits the reaction [manganese chloride results in increased phosphorylation of JUN protein] CTD PMID:9751194 PMID:15342272 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kcng1 potassium voltage-gated channel modifier subfamily G member 1 increases expression EXP manganese chloride results in increased expression of KCNG1 mRNA CTD PMID:28801915 NCBI chr 3:165,020,230...165,040,966
Ensembl chr 3:165,020,230...165,039,707
JBrowse link
G Kcnh4 potassium voltage-gated channel subfamily H member 4 decreases expression EXP manganese chloride results in decreased expression of KCNH4 mRNA CTD PMID:28801915 NCBI chr10:88,645,341...88,667,447
Ensembl chr10:88,647,575...88,667,345
JBrowse link
G Kcnh6 potassium voltage-gated channel subfamily H member 6 increases expression EXP manganese chloride results in increased expression of KCNH6 mRNA CTD PMID:28801915 NCBI chr10:94,207,336...94,228,236
Ensembl chr10:94,207,314...94,228,236
JBrowse link
G Kcnip3 potassium voltage-gated channel interacting protein 3 increases expression ISO manganese chloride results in increased expression of KCNIP3 mRNA CTD PMID:17175027 NCBI chr 3:120,023,062...120,087,650
Ensembl chr 3:120,023,917...120,087,136
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of KCNJ11 protein CTD PMID:32659473 NCBI chr 1:102,103,093...102,107,134
Ensembl chr 1:102,103,094...102,106,127
JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 increases expression ISO manganese chloride results in increased expression of KCNJ3 mRNA CTD PMID:17175027 NCBI chr 3:41,019,898...41,181,070
Ensembl chr 3:41,019,898...41,181,070
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of KCNJ8 protein CTD PMID:32659473 NCBI chr 4:176,783,287...176,789,143
Ensembl chr 4:176,782,498...176,789,304
JBrowse link
G Kcnk12 potassium two pore domain channel subfamily K member 12 decreases expression EXP manganese chloride results in decreased expression of KCNK12 mRNA CTD PMID:28801915 NCBI chr 6:11,373,917...11,494,459
Ensembl chr 6:11,373,917...11,494,459
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 increases expression EXP manganese chloride results in increased expression of KCNQ1 mRNA CTD PMID:28801915 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339
JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 increases expression EXP manganese chloride results in increased expression of KCNQ2 mRNA CTD PMID:28801915 NCBI chr 3:176,585,897...176,645,029
Ensembl chr 3:176,589,906...176,644,951
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 affects expression
multiple interactions
ISO manganese chloride affects the expression of KEAP1 protein
Melatonin affects the reaction [manganese chloride affects the expression of KEAP1 protein]
CTD PMID:25288107 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Kera keratocan increases expression EXP manganese chloride results in increased expression of KERA mRNA CTD PMID:26745496 NCBI chr 7:38,858,062...38,865,515
Ensembl chr 7:38,858,062...38,865,515
JBrowse link
G Kif3b kinesin family member 3B increases expression EXP manganese chloride results in increased expression of KIF3B mRNA CTD PMID:28801915 NCBI chr 3:148,772,937...148,813,342
Ensembl chr 3:148,773,259...148,813,293
JBrowse link
G Kif5c kinesin family member 5C increases expression EXP manganese chloride results in increased expression of KIF5C mRNA CTD PMID:28801915 NCBI chr 3:35,014,157...35,257,417
Ensembl chr 3:35,014,538...35,257,407
JBrowse link
G Kiss1r KISS1 receptor increases expression EXP manganese chloride results in increased expression of KISS1R mRNA CTD PMID:28801915 NCBI chr 7:12,606,210...12,609,868
Ensembl chr 7:12,606,210...12,609,868
JBrowse link
G Klf2 Kruppel-like factor 2 increases expression EXP manganese chloride results in increased expression of KLF2 mRNA CTD PMID:28801915 NCBI chr16:19,223,087...19,225,037
Ensembl chr16:19,223,087...19,225,037
JBrowse link
G Klf4 Kruppel like factor 4 increases expression ISO manganese chloride results in increased expression of KLF4 mRNA CTD PMID:17175027 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
JBrowse link
G Klf5 Kruppel-like factor 5 decreases expression
decreases methylation
increases expression
ISO
EXP
manganese chloride results in decreased expression of KLF5 mRNA
manganese chloride results in decreased methylation of KLF5 gene
manganese chloride results in increased expression of KLF5 mRNA
CTD PMID:17467022 PMID:28801915 NCBI chr15:83,703,796...83,722,921
Ensembl chr15:83,703,791...83,722,921
JBrowse link
G Klf9 Kruppel-like factor 9 decreases expression ISO manganese chloride results in decreased expression of KLF9 mRNA CTD PMID:17175027 NCBI chr 1:240,908,483...240,933,198
Ensembl chr 1:240,908,483...240,933,198
JBrowse link
G Klhdc8a kelch domain containing 8A increases expression EXP manganese chloride results in increased expression of KLHDC8A mRNA CTD PMID:28801915 NCBI chr13:49,074,644...49,082,729
Ensembl chr13:49,074,644...49,082,729
JBrowse link
G Kng2 kininogen 2 decreases expression EXP manganese chloride results in decreased expression of KNG1 mRNA CTD PMID:28801915 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Krt7 keratin 7 increases expression EXP manganese chloride results in increased expression of KRT7 mRNA CTD PMID:28801915 NCBI chr 7:143,059,731...143,075,907
Ensembl chr 7:143,059,764...143,075,907
JBrowse link
G Krt76 keratin 76 increases expression EXP manganese chloride results in increased expression of KRT76 mRNA CTD PMID:28801915 NCBI chr 7:143,488,668...143,497,108
Ensembl chr 7:143,488,684...143,497,108
JBrowse link
G Krt79 keratin 79 decreases expression EXP manganese chloride results in decreased expression of KRT79 mRNA CTD PMID:28801915 NCBI chr 7:143,528,204...143,538,713
Ensembl chr 7:143,528,204...143,538,579
JBrowse link
G Krt81 keratin 81 increases expression EXP manganese chloride results in increased expression of KRT81 mRNA CTD PMID:28801915 NCBI chr 7:143,107,901...143,113,006
Ensembl chr 7:143,107,901...143,112,960
JBrowse link
G Krt83 keratin 83 increases expression EXP manganese chloride results in increased expression of KRT83 mRNA CTD PMID:28801915 NCBI chr 7:143,078,996...143,085,833
Ensembl chr 7:143,078,996...143,085,833
JBrowse link
G Krtap1-3 keratin associated protein 1-3 increases expression EXP manganese chloride results in increased expression of KRTAP1-3 mRNA CTD PMID:28801915 NCBI chr10:87,509,822...87,510,645
Ensembl chr10:87,510,101...87,510,629
JBrowse link
G Lacc1 laccase domain containing 1 increases expression EXP manganese chloride results in increased expression of LACC1 mRNA CTD PMID:28801915 NCBI chr15:59,199,537...59,217,200
Ensembl chr15:59,209,829...59,215,803
JBrowse link
G Lcat lecithin cholesterol acyltransferase increases expression EXP manganese chloride results in increased expression of LCAT mRNA CTD PMID:28801915 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase multiple interactions ISO [manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein; Tetradecanoylphorbol Acetate inhibits the reaction [[manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein] CTD PMID:8662792 NCBI chr 5:147,750,976...147,779,627
Ensembl chr 5:147,750,973...147,761,983
JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 increases expression EXP manganese chloride results in increased expression of LDLRAD4 mRNA CTD PMID:28801915 NCBI chr18:63,717,423...64,045,224
Ensembl chr18:63,882,610...64,044,023
JBrowse link
G Lgals3 galectin 3 increases expression EXP manganese chloride results in increased expression of LGALS3 mRNA CTD PMID:28801915 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lgi4 leucine-rich repeat LGI family, member 4 increases expression EXP manganese chloride results in increased expression of LGI4 mRNA CTD PMID:28801915 NCBI chr 1:89,491,588...89,502,939
Ensembl chr 1:89,491,654...89,502,974
JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 decreases expression EXP manganese chloride results in decreased expression of LGR4 mRNA CTD PMID:28801915 NCBI chr 3:101,051,960...101,152,119
Ensembl chr 3:101,051,955...101,152,119
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions
decreases expression
EXP Quercetin inhibits the reaction [manganese chloride results in decreased expression of LHB protein] CTD PMID:28040552 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Lhfpl2 LHFPL tetraspan subfamily member 2 increases expression EXP manganese chloride results in increased expression of LHFPL2 mRNA CTD PMID:28801915 NCBI chr 2:23,705,491...23,852,021
Ensembl chr 2:23,770,721...23,852,021
JBrowse link
G Lhx1 LIM homeobox 1 decreases expression EXP manganese chloride results in decreased expression of LHX1 mRNA CTD PMID:28801915 NCBI chr10:71,843,991...71,849,293
Ensembl chr10:71,843,991...71,849,293
JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression EXP manganese chloride results in increased expression of LIF mRNA CTD PMID:28801915 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Lman2 lectin, mannose-binding 2 increases expression ISO manganese chloride results in increased expression of LMAN2 mRNA CTD PMID:17175027 NCBI chr17:9,798,136...9,815,820
Ensembl chr17:9,797,907...9,816,139
JBrowse link
G Lmod2 leiomodin 2 decreases expression EXP manganese chloride results in decreased expression of LMOD2 mRNA CTD PMID:28801915 NCBI chr 4:51,553,439...51,561,135
Ensembl chr 4:51,553,454...51,561,174
JBrowse link
G LOC102555183 zinc finger protein OZF-like increases expression EXP manganese chloride results in increased expression of ZFP146 mRNA CTD PMID:28801915 NCBI chr10:74,767,535...74,770,723
Ensembl chr10:74,768,759...74,769,637
JBrowse link
G Lox lysyl oxidase decreases expression EXP manganese chloride results in decreased expression of LOX mRNA CTD PMID:28801915 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Lpal2 lipoprotein(a) like 2, pseudogene decreases expression EXP manganese chloride results in decreased expression of LPAL2 mRNA CTD PMID:28801915 NCBI chr 4:165,682,977...165,737,759
Ensembl chr 4:165,732,643...165,737,755
JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 decreases expression EXP manganese chloride results in decreased expression of LPAR1 mRNA CTD PMID:28801915 NCBI chr 5:75,557,038...75,678,067
Ensembl chr 5:75,557,042...75,676,584
JBrowse link
G Lpcat4 lysophosphatidylcholine acyltransferase 4 decreases expression EXP manganese chloride results in decreased expression of LPCAT4 mRNA CTD PMID:28801915 NCBI chr 3:103,725,762...103,733,888
Ensembl chr 3:103,726,238...103,733,354
JBrowse link
G Lpin1 lipin 1 decreases expression EXP manganese chloride results in decreased expression of LPIN1 mRNA CTD PMID:28801915 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
G Lrat lecithin retinol acyltransferase increases expression EXP manganese chloride results in increased expression of LRAT mRNA CTD PMID:26745496 NCBI chr 2:181,896,304...181,905,366
Ensembl chr 2:181,896,305...181,905,300
JBrowse link
G Lrp2 LDL receptor related protein 2 decreases expression EXP manganese chloride results in decreased expression of LRP2 mRNA CTD PMID:28801915 NCBI chr 3:55,665,153...55,822,484
Ensembl chr 3:55,665,145...55,822,551
JBrowse link
G Lrp8 LDL receptor related protein 8 increases expression ISO manganese chloride results in increased expression of LRP8 mRNA CTD PMID:22407947 NCBI chr 5:127,404,348...127,476,636
Ensembl chr 5:127,404,450...127,476,641
JBrowse link
G Lrrc10b leucine rich repeat containing 10B increases methylation EXP manganese chloride results in increased methylation of LRRC10B gene CTD PMID:28801915 NCBI chr 1:226,500,692...226,501,920
Ensembl chr 1:226,500,692...226,501,920
JBrowse link
G Lrrc15 leucine rich repeat containing 15 increases expression EXP manganese chloride results in increased expression of LRRC15 mRNA CTD PMID:28801915 NCBI chr11:74,040,846...74,052,179
Ensembl chr11:74,050,166...74,051,902
JBrowse link
G Lrrc8b leucine rich repeat containing 8 VRAC subunit B increases expression EXP manganese chloride results in increased expression of LRRC8B mRNA CTD PMID:28801915 NCBI chr14:5,414,872...5,482,004
Ensembl chr14:5,418,741...5,428,757
JBrowse link
G Lrrk1 leucine-rich repeat kinase 1 increases expression EXP manganese chloride results in increased expression of LRRK1 mRNA CTD PMID:28801915 NCBI chr 1:127,166,866...127,301,053
Ensembl chr 1:127,166,431...127,292,090
JBrowse link
G Ly6g5b lymphocyte antigen 6 family member G5B increases expression EXP manganese chloride results in increased expression of LY6G5B mRNA CTD PMID:28801915 NCBI chr20:5,106,248...5,108,604
Ensembl chr20:5,106,890...5,107,899
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase decreases methylation ISO manganese chloride results in decreased methylation of LYN gene CTD PMID:27913844 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648
JBrowse link
G Lypd6b LY6/PLAUR domain containing 6B decreases expression EXP manganese chloride results in decreased expression of LYPD6B mRNA CTD PMID:28801915 NCBI chr 3:35,271,785...35,437,296
Ensembl chr 3:35,271,786...35,437,296
JBrowse link
G Lyrm7 LYR motif containing 7 increases expression EXP manganese chloride results in increased expression of LYRM7 mRNA CTD PMID:28801915 NCBI chr10:40,183,061...40,201,992
Ensembl chr10:40,183,078...40,201,992
JBrowse link
G Lyrm9 LYR motif containing 9 increases expression EXP manganese chloride results in increased expression of LYRM9 mRNA CTD PMID:28801915 NCBI chr10:66,099,478...66,113,559
Ensembl chr10:66,099,531...66,113,559
JBrowse link
G Macrod2 mono-ADP ribosylhydrolase 2 increases expression EXP manganese chloride results in increased expression of MACROD2 mRNA CTD PMID:28801915 NCBI chr 3:135,729,839...136,422,082 JBrowse link
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 increases expression EXP manganese chloride results in increased expression of MADCAM1 mRNA CTD PMID:28801915 NCBI chr 7:12,918,352...12,922,509
Ensembl chr 7:12,918,710...12,922,112
JBrowse link
G Maff MAF bZIP transcription factor F increases expression EXP manganese chloride results in increased expression of MAFF mRNA CTD PMID:28801915 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Mageb7 MAGE family member B7 increases expression EXP manganese chloride results in increased expression of MAGEB7 mRNA CTD PMID:28801915 NCBI chr  X:54,938,470...54,941,813
Ensembl chr  X:54,938,845...54,939,919
JBrowse link
G Mall mal, T-cell differentiation protein-like decreases expression EXP manganese chloride results in decreased expression of MALL mRNA CTD PMID:26745496 NCBI chr 3:120,272,583...120,307,090
Ensembl chr 3:120,272,583...120,306,551
JBrowse link
G Map2 microtubule-associated protein 2 decreases expression EXP manganese chloride results in decreased expression of MAP2 mRNA CTD PMID:28801915 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 decreases methylation ISO manganese chloride results in decreased methylation of MAP2K3 gene CTD PMID:27913844 NCBI chr10:45,089,455...45,110,802
Ensembl chr10:47,182,433...47,203,753
Ensembl chr10:47,182,433...47,203,753
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 increases phosphorylation EXP manganese chloride results in increased phosphorylation of MAP2K4 protein CTD PMID:9751194 PMID:15342272 NCBI chr10:52,196,121...52,301,887
Ensembl chr10:52,196,124...52,290,657
JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 increases phosphorylation EXP manganese chloride results in increased phosphorylation of MAP3K11 protein CTD PMID:15342272 NCBI chr 1:221,043,119...221,056,420
Ensembl chr 1:221,043,119...221,056,417
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 increases methylation ISO manganese chloride results in increased methylation of MAP3K7 gene CTD PMID:27913844 NCBI chr 5:47,183,142...47,244,424
Ensembl chr 5:47,186,558...47,244,416
Ensembl chr 9:47,186,558...47,244,416
JBrowse link
G Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 decreases expression EXP manganese chloride results in decreased expression of MAP4K3 mRNA CTD PMID:28801915 NCBI chr 6:3,276,732...3,444,519
Ensembl chr 6:3,276,738...3,444,519
JBrowse link
G Map7 microtubule-associated protein 7 increases expression EXP manganese chloride results in increased expression of MAP7 mRNA CTD PMID:28801915 NCBI chr 1:15,620,665...15,748,203
Ensembl chr 1:15,620,653...15,748,203
JBrowse link
G Map7d2 MAP7 domain containing 2 increases methylation
decreases expression
EXP manganese chloride results in increased methylation of MAP7D2 gene
manganese chloride results in decreased expression of MAP7D2 mRNA
CTD PMID:28801915 NCBI chr  X:38,400,578...38,467,825
Ensembl chr  X:38,397,261...38,468,360
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
decreases phosphorylation
increases activity
EXP
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK1 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK1 protein; GW 506033X promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK1 protein]; manganese chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein; pyrazolanthrone promotes the reaction [manganese chloride results in increased phosphorylation of MAPK1 protein]; Resveratrol inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK1 protein]
NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK1 protein]
[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK1 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK1 protein]
manganese chloride results in decreased phosphorylation of MAPK1 protein
manganese chloride results in increased activity of MAPK1 protein
CTD PMID:15010209 PMID:15342272 PMID:16787641 PMID:19084589 PMID:20152896 PMID:20937724 PMID:23811825 PMID:24324973 PMID:25981801 PMID:30040983 PMID:31676349 PMID:32574669 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 increases expression EXP manganese chloride results in increased expression of MAPK11 mRNA CTD PMID:28801915 NCBI chr 7:130,121,678...130,129,199
Ensembl chr 7:130,121,687...130,128,604
JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation
increases expression
ISO manganese chloride results in increased phosphorylation of MAPK14 protein
manganese chloride results in increased expression of MAPK14 mRNA
CTD PMID:15737199 PMID:17467022 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
decreases phosphorylation
increases activity
EXP
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK3 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK3 protein; GW 506033X promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK3 protein]; manganese chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein; pyrazolanthrone promotes the reaction [manganese chloride results in increased phosphorylation of MAPK3 protein]; Resveratrol inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK3 protein]
[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK3 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK3 protein]
NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK3 protein]
manganese chloride results in decreased phosphorylation of MAPK3 protein
manganese chloride results in increased activity of MAPK3 protein
CTD PMID:15010209 PMID:15342272 PMID:16787641 PMID:19084589 PMID:20152896 PMID:20937724 PMID:23811825 PMID:24324973 PMID:25981801 PMID:30040983 PMID:31676349 PMID:32574669 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases activity
multiple interactions
increases methylation
increases phosphorylation
ISO
EXP
manganese chloride results in increased activity of MAPK8 protein
[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein; pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein]
manganese chloride results in increased methylation of MAPK8 gene
manganese chloride results in increased phosphorylation of MAPK8 protein
CTD PMID:19084589 PMID:20152896 PMID:24324973 PMID:27913844 PMID:30951808 PMID:32574669 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases activity
increases phosphorylation
ISO manganese chloride results in increased activity of MAPK9 protein
manganese chloride results in increased phosphorylation of MAPK9 protein
CTD PMID:19084589 PMID:20152896 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions
increases phosphorylation
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; [Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; GSK3B protein affects the reaction [manganese chloride results in increased phosphorylation of MAPT protein] CTD PMID:20937724 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Masp1 MBL associated serine protease 1 decreases methylation ISO manganese chloride results in decreased methylation of MASP1 gene CTD PMID:27913844 NCBI chr11:80,736,424...80,806,278
Ensembl chr11:80,736,576...80,803,382
JBrowse link
G Matn3 matrilin 3 decreases expression EXP manganese chloride results in decreased expression of MATN3 mRNA CTD PMID:28801915 NCBI chr 6:34,071,428...34,091,048
Ensembl chr 6:34,071,428...34,091,048
JBrowse link
G Mbp myelin basic protein increases expression ISO manganese chloride results in increased expression of MBP mRNA CTD PMID:17175027 NCBI chr18:79,326,738...79,437,310
Ensembl chr18:79,326,738...79,437,310
JBrowse link
G Mcf2l MCF.2 cell line derived transforming sequence-like increases expression ISO manganese chloride results in increased expression of MCF2L mRNA CTD PMID:15295902 NCBI chr16:81,839,686...81,986,007
Ensembl chr16:81,839,653...81,980,027
JBrowse link
G Mchr1 melanin-concentrating hormone receptor 1 increases expression ISO manganese chloride results in increased expression of MCHR1 mRNA CTD PMID:17175027 NCBI chr 7:122,456,846...122,459,324
Ensembl chr 7:122,456,799...122,459,960
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression EXP manganese chloride results in decreased expression of MCL1 protein CTD PMID:27107493 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mcm4 minichromosome maintenance complex component 4 decreases expression ISO manganese chloride results in decreased expression of MCM4 mRNA CTD PMID:17175027 NCBI chr11:89,511,191...89,524,892
Ensembl chr11:89,511,191...89,524,892
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO manganese chloride results in decreased expression of MCM5 mRNA CTD PMID:17175027 NCBI chr19:14,523,482...14,561,281
Ensembl chr19:14,523,554...14,561,278
JBrowse link
G Mcoln3 mucolipin TRP cation channel 3 increases expression EXP manganese chloride results in increased expression of MCOLN3 mRNA CTD PMID:26745496 NCBI chr 2:251,930,532...252,007,722
Ensembl chr 2:251,983,339...252,007,560
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP manganese chloride results in increased expression of MDM2 mRNA CTD PMID:28801915 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Me3 malic enzyme 3 increases expression ISO manganese chloride results in increased expression of ME3 mRNA CTD PMID:17175027 NCBI chr 1:153,861,535...154,058,608
Ensembl chr 1:153,861,569...154,056,654
JBrowse link
G Medag mesenteric estrogen-dependent adipogenesis increases expression EXP manganese chloride results in increased expression of MEDAG mRNA CTD PMID:28801915 NCBI chr12:6,711,745...6,730,959
Ensembl chr12:6,711,747...6,740,714
JBrowse link
G Mef2c myocyte enhancer factor 2C decreases expression
increases methylation
EXP manganese chloride results in decreased expression of MEF2C mRNA
manganese chloride results in increased methylation of MEF2C gene
CTD PMID:28801915 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link
G Mepe matrix extracellular phosphoglycoprotein increases methylation
increases expression
EXP manganese chloride results in increased methylation of MEPE gene
manganese chloride results in increased expression of MEPE mRNA
CTD PMID:28801915 NCBI chr14:6,782,011...6,793,561
Ensembl chr14:6,782,012...6,793,558
JBrowse link
G Metap2 methionyl aminopeptidase 2 multiple interactions
increases activity
ISO manganese chloride inhibits the reaction [Triazoles results in decreased activity of METAP2 protein]
manganese chloride results in increased activity of METAP2 protein
CTD PMID:12718546 NCBI chr 7:34,762,241...34,789,456
Ensembl chr 7:34,762,231...34,789,479
JBrowse link
G Mfap2 microfibril associated protein 2 decreases expression
decreases methylation
EXP manganese chloride results in decreased expression of MFAP2 mRNA
manganese chloride results in decreased methylation of MFAP2 gene
CTD PMID:28801915 NCBI chr 5:159,534,202...159,539,750
Ensembl chr 5:159,534,202...159,539,750
JBrowse link
G Mfn2 mitofusin 2 decreases expression ISO manganese chloride results in decreased expression of MFN2 mRNA; manganese chloride results in decreased expression of MFN2 protein CTD PMID:28539244 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mfsd6 major facilitator superfamily domain containing 6 increases expression EXP manganese chloride results in increased expression of MFSD6 mRNA CTD PMID:28801915 NCBI chr 9:53,626,412...53,710,820
Ensembl chr 9:53,626,592...53,710,817
JBrowse link
G Mga MAX dimerization protein MGA increases expression EXP manganese chloride results in increased expression of MGA mRNA CTD PMID:28801915 NCBI chr 3:111,669,645...111,760,822
Ensembl chr 3:111,699,021...111,759,911
JBrowse link
G Mgat1 alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase increases expression ISO manganese chloride results in increased expression of MGAT1 mRNA CTD PMID:15295902 NCBI chr10:34,518,392...34,537,214
Ensembl chr10:34,519,790...34,537,210
JBrowse link
G Mgat5b alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B increases expression EXP manganese chloride results in increased expression of MGAT5B mRNA CTD PMID:28801915 NCBI chr10:105,861,734...105,932,048
Ensembl chr10:105,861,743...105,932,042
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases methylation
increases expression
ISO
EXP
manganese chloride results in increased methylation of MGMT gene
manganese chloride results in increased expression of MGMT mRNA
CTD PMID:27913844 PMID:28801915 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mgp matrix Gla protein increases expression EXP manganese chloride results in increased expression of MGP mRNA CTD PMID:28801915 NCBI chr 4:170,856,783...170,860,105
Ensembl chr 4:170,856,751...170,860,225
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 decreases expression EXP manganese chloride results in decreased expression of MGST1 mRNA CTD PMID:28801915 NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 increases expression EXP manganese chloride results in increased expression of MGST3 mRNA CTD PMID:28801915 NCBI chr13:85,601,499...85,622,392
Ensembl chr13:85,601,499...85,622,314
JBrowse link
G Mia MIA SH3 domain containing increases expression ISO
EXP
manganese chloride results in increased expression of MIA mRNA CTD PMID:17175027 PMID:28801915 NCBI chr 1:83,991,577...83,993,270
Ensembl chr 1:83,991,578...83,993,270
JBrowse link
G Mical1 microtubule associated monooxygenase, calponin and LIM domain containing 1 decreases expression EXP manganese chloride results in decreased expression of MICAL1 mRNA CTD PMID:28801915 NCBI chr20:46,199,981...46,211,930
Ensembl chr20:46,199,981...46,211,930
JBrowse link
G Mir107 microRNA 107 decreases expression ISO manganese chloride results in decreased expression of MIR107 mRNA CTD PMID:28986288 NCBI chr 1:253,128,250...253,128,336
Ensembl chr 1:253,128,250...253,128,336
JBrowse link
G Mir125b1 microRNA 125b-1 multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in increased expression of MIR125B1 mRNA CTD PMID:31555879 NCBI chr 8:45,798,260...45,798,346
Ensembl chr 8:45,798,260...45,798,346
JBrowse link
G Mir134 microRNA 134 increases expression ISO manganese chloride results in increased expression of MIR134 mRNA CTD PMID:28986288 NCBI chr 6:133,884,547...133,884,619
Ensembl chr 6:133,884,531...133,884,633
JBrowse link
G Mir139 microRNA 139 decreases expression ISO manganese chloride results in decreased expression of MIR139 mRNA CTD PMID:28986288 NCBI chr 1:166,589,545...166,589,612
Ensembl chr 1:166,589,545...166,589,612
JBrowse link
G Mir146b microRNA 146b decreases expression ISO manganese chloride results in decreased expression of MIR146B mRNA CTD PMID:28986288 NCBI chr 1:266,089,488...266,089,575
Ensembl chr 1:266,089,488...266,089,575
JBrowse link
G Mir298 microRNA 298 decreases expression ISO manganese chloride results in decreased expression of MIR298 mRNA CTD PMID:28986288 NCBI chr 3:172,357,943...172,358,024
Ensembl chr 3:172,357,943...172,358,024
JBrowse link
G Mir29a microRNA 29a decreases expression ISO manganese chloride results in decreased expression of MIR29A mRNA CTD PMID:28986288 NCBI chr 4:58,343,931...58,344,018 JBrowse link
G Mir320a microRNA 320a increases expression ISO manganese chloride results in increased expression of MIR320A mRNA CTD PMID:28986288 NCBI chr15:52,134,276...52,134,357
Ensembl chr15:52,134,276...52,134,357
JBrowse link
G Mir328 microRNA 328 decreases expression ISO manganese chloride results in decreased expression of MIR328 mRNA CTD PMID:28986288 NCBI chr19:37,263,199...37,263,282
Ensembl chr19:37,263,199...37,263,282
JBrowse link
G Mir409 microRNA 409 decreases expression ISO manganese chloride results in decreased expression of MIR409 mRNA CTD PMID:28986288 NCBI chr 6:133,893,419...133,893,495 JBrowse link
G Mir433 microRNA 433 decreases expression ISO manganese chloride results in decreased expression of MIR433 mRNA CTD PMID:28986288 NCBI chr 6:133,712,334...133,712,426
Ensembl chr 6:133,712,334...133,712,426
JBrowse link
G Mir582 microRNA 582 multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in decreased expression of MIR582 mRNA CTD PMID:31555879 NCBI chr 2:40,863,750...40,863,830
Ensembl chr 2:40,863,750...40,863,830
JBrowse link
G Mir98 microRNA 98 decreases expression ISO manganese chloride results in decreased expression of MIR98 mRNA CTD PMID:28986288 NCBI chr  X:21,583,875...21,583,982
Ensembl chr  X:21,583,875...21,583,982
JBrowse link
G Mirlet7b microRNA let-7b increases expression ISO manganese chloride results in increased expression of MIRLET7B mRNA CTD PMID:28986288 NCBI chr 7:126,590,627...126,590,711
Ensembl chr 7:126,590,627...126,590,711
JBrowse link
G Mmab metabolism of cobalamin associated B decreases expression EXP manganese chloride results in decreased expression of MMAB mRNA CTD PMID:28801915 NCBI chr12:47,920,712...47,935,438
Ensembl chr12:47,920,743...47,935,525
JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression EXP manganese chloride results in increased expression of MMP13 mRNA CTD PMID:26745496 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp14 matrix metallopeptidase 14 decreases expression
increases methylation
EXP manganese chloride results in decreased expression of MMP14 mRNA
manganese chloride results in increased methylation of MMP14 gene
CTD PMID:28801915 NCBI chr15:33,074,441...33,083,666
Ensembl chr15:33,074,441...33,083,655
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G Mmp24 matrix metallopeptidase 24 increases expression EXP manganese chloride results in increased expression of MMP24 mRNA CTD PMID:28801915 NCBI chr 3:151,307,309...151,355,401
Ensembl chr 3:151,310,598...151,355,401
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression EXP manganese chloride results in increased expression of MMP3 mRNA CTD PMID:26745496 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased expression of and results in increased secretion of MMP9 protein]; manganese chloride results in increased expression of and results in increased secretion of MMP9 protein; resveratrol inhibits the reaction [manganese chloride results in increased expression of and results in increased secretion of MMP9 protein]; resveratrol inhibits the reaction [manganese chloride results in increased expression of MMP9 mRNA] CTD PMID:23811825 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
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G Mnda myeloid cell nuclear differentiation antigen decreases expression EXP manganese chloride results in decreased expression of IFI204 mRNA CTD PMID:28801915 NCBI chr13:92,073,664...92,091,335
Ensembl chr13:92,073,668...92,089,980
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G Mob3b MOB kinase activator 3B increases expression EXP manganese chloride results in increased expression of MOB3B mRNA CTD PMID:28801915 NCBI chr 5:50,437,444...50,638,136
Ensembl chr 5:50,438,576...50,638,136
JBrowse link
G Mon2 MON2 homolog, regulator of endosome-to-Golgi trafficking decreases expression EXP manganese chloride results in decreased expression of MON2 mRNA CTD PMID:28801915 NCBI chr 7:66,717,470...66,794,041
Ensembl chr 7:66,717,267...66,792,492
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G Mpc1l mitochondrial pyruvate carrier 1-like increases expression EXP manganese chloride results in increased expression of MPC1L mRNA CTD PMID:28801915 NCBI chr  X:11,098,849...11,105,312 JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
ISO
EXP
diphenyleneiodonium inhibits the reaction [manganese chloride promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased activity of MPO protein]]; manganese chloride promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased activity of MPO protein]; manganese chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; Sodium Azide inhibits the reaction [manganese chloride promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased activity of MPO protein]]
manganese chloride results in increased activity of MPO protein
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased activity of MPO protein]; [manganese chloride results in increased abundance of Manganese] which results in increased activity of MPO protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased activity of MPO protein]; Quercetin inhibits the reaction [manganese chloride results in increased activity of MPO protein]
CTD PMID:22906169 PMID:28040552 PMID:30844427 PMID:33314588 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
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G Mpp3 membrane palmitoylated protein 3 increases expression EXP manganese chloride results in increased expression of MPP3 mRNA CTD PMID:28801915 NCBI chr10:89,930,270...89,959,462
Ensembl chr10:89,930,241...89,959,176
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G Mrps10 mitochondrial ribosomal protein S10 decreases expression EXP manganese chloride results in decreased expression of MRPS10 mRNA CTD PMID:28801915 NCBI chr 9:15,637,427...15,651,154
Ensembl chr 9:15,637,268...15,646,846
JBrowse link
G Ms4a6a membrane spanning 4-domains A6A increases expression EXP manganese chloride results in increased expression of MS4A6A mRNA CTD PMID:28801915 NCBI chr 1:227,919,284...227,932,637
Ensembl chr 1:227,919,301...227,932,603
JBrowse link
G Msh5 mutS homolog 5 increases expression EXP manganese chloride results in increased expression of MSH5 mRNA CTD PMID:28801915 NCBI chr20:5,020,690...5,037,125
Ensembl chr20:5,020,667...5,037,088
JBrowse link
G Msh6 mutS homolog 6 decreases expression ISO manganese chloride results in decreased expression of MSH6 mRNA CTD PMID:17175027 NCBI chr 6:11,644,565...11,662,389
Ensembl chr 6:11,644,578...11,662,499
JBrowse link
G Msx2 msh homeobox 2 decreases expression EXP manganese chloride results in decreased expression of MSX2 mRNA CTD PMID:28801915 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527
JBrowse link
G Mt1 metallothionein 1 decreases expression EXP manganese chloride results in decreased expression of MT1A mRNA CTD PMID:12387356 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt3 metallothionein 3 increases expression EXP manganese chloride results in increased expression of MT3 mRNA CTD PMID:28801915 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Mta1 metastasis associated 1 increases expression EXP manganese chloride results in increased expression of MTA1 mRNA CTD PMID:28801915 NCBI chr 6:137,911,302...137,950,066
Ensembl chr 6:137,924,293...137,950,075
JBrowse link
G Mtap methylthioadenosine phosphorylase increases expression EXP manganese chloride results in increased expression of MTAP mRNA CTD PMID:28801915 NCBI chr 5:107,711,077...107,777,530
Ensembl chr 5:107,711,077...107,777,530
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase increases expression
increases methylation
EXP manganese chloride results in increased expression of MTHFD2 mRNA
manganese chloride results in increased methylation of MTHFD2 gene
CTD PMID:28801915 NCBI chr 4:115,004,433...115,015,965
Ensembl chr 4:115,004,448...115,015,965
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like increases expression EXP manganese chloride results in increased expression of MTHFD2L mRNA CTD PMID:28801915 NCBI chr14:18,640,274...18,721,298
Ensembl chr14:18,640,277...18,720,357
JBrowse link
G Mtm1 myotubularin 1 decreases expression ISO manganese chloride results in decreased expression of MTM1 mRNA CTD PMID:17175027 NCBI chr 6:18,821,821...18,840,449
Ensembl chr 6:18,821,815...18,839,409
JBrowse link
G Mtmr10 myotubularin related protein 10 increases expression EXP manganese chloride results in increased expression of MTMR10 mRNA CTD PMID:28801915 NCBI chr 1:125,124,743...125,175,857
Ensembl chr 1:125,124,743...125,175,857
JBrowse link
G Mtmr6 myotubularin related protein 6 decreases expression EXP manganese chloride results in decreased expression of MTMR6 mRNA CTD PMID:28801915 NCBI chr15:40,558,917...40,597,311
Ensembl chr15:40,558,932...40,597,309
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation
multiple interactions
increases phosphorylation
EXP
ISO
manganese chloride results in decreased phosphorylation of MTOR protein
corynoxine B promotes the reaction [manganese chloride results in decreased phosphorylation of MTOR protein]
manganese chloride results in increased phosphorylation of MTOR protein
CTD PMID:23604964 PMID:30578841 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Mxd4 Max dimerization protein 4 decreases expression EXP manganese chloride results in decreased expression of MXD4 mRNA CTD PMID:28801915 NCBI chr14:81,819,415...81,833,456
Ensembl chr14:81,819,415...81,833,456
JBrowse link
G Myh13 myosin heavy chain 13 increases expression EXP manganese chloride results in increased expression of MYH13 mRNA CTD PMID:28801915 NCBI chr10:53,873,089...53,920,698 JBrowse link
G Myh2 myosin heavy chain 2 decreases expression EXP manganese chloride results in decreased expression of MYH2 mRNA CTD PMID:26745496 NCBI chr10:53,711,895...53,738,164
Ensembl chr10:53,713,938...53,848,347
JBrowse link
G Mylk2 myosin light chain kinase 2 increases expression EXP manganese chloride results in increased expression of MYLK2 mRNA CTD PMID:28801915 NCBI chr 3:148,386,185...148,397,851
Ensembl chr 3:148,386,189...148,399,501
JBrowse link
G Mylk3 myosin light chain kinase 3 increases expression EXP manganese chloride results in increased expression of MYLK3 mRNA CTD PMID:28801915 NCBI chr19:27,388,163...27,442,451
Ensembl chr19:27,404,712...27,441,536
JBrowse link
G Myoc myocilin increases methylation EXP manganese chloride results in increased methylation of MYOC gene CTD PMID:28801915 NCBI chr13:80,517,531...80,527,928
Ensembl chr13:80,517,536...80,527,928
JBrowse link
G Myom1 myomesin 1 increases expression
decreases expression
ISO
EXP
manganese chloride results in increased expression of MYOM1 mRNA
manganese chloride results in decreased expression of MYOM1 mRNA
CTD PMID:17175027 PMID:28801915 NCBI chr 9:119,353,840...119,469,196
Ensembl chr 9:119,353,840...119,468,715