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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:manganese(II) chloride
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Accession:CHEBI:63041 term browser browse the term
Definition:An inorganic chloride in which manganese(II) is coordinated to two chloride ions. In its anhydrous state manganese(II) chloride is a polymeric solid, which adopts a layered cadmium chloride-like structure.
Synonyms:exact_synonym: manganese(2+) dichloride
 related_synonym: Formula=Cl2Mn;   InChI=1S/2ClH.Mn/h2*1H;/q;;+2/p-2;   InChIKey=GLFNIEUTAYBVOC-UHFFFAOYSA-L;   Mangandichlorid;   Manganese bichloride;   Manganese(II) chloride (1:2);   Manganous chloride;   SMILES=Cl[Mn]Cl;   dichlorure de manganese;   manganese(II) dichloride;   manganous dichloride
 xref: CAS:7773-01-5
 xref_mesh: MESH:C025340
 xref: MetaCyc:CPD0-2394;   PMID:101555;   PMID:146543;   PMID:19801673;   PMID:3143594;   PMID:4476198;   PMID:4771199;   PMID:98204;   Reaxys:8128170;   Wikipedia:Manganese(II)_chloride



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manganese(II) chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca5 ATP binding cassette subfamily A member 5 decreases expression ISO manganese chloride results in decreased expression of ABCA5 mRNA CTD PMID:17175027 NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976
JBrowse link
G Abca9 ATP binding cassette subfamily A member 9 increases expression ISO manganese chloride results in increased expression of ABCA9 mRNA CTD PMID:17175027 NCBI chr10:95,077,615...95,137,751
Ensembl chr10:95,079,058...95,139,608
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression EXP manganese chloride results in increased expression of ABCB1A mRNA CTD PMID:26745496 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP manganese chloride results in increased expression of ABCB1B mRNA CTD PMID:28801915 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression
decreases methylation
EXP manganese chloride results in increased expression of ABCC2 mRNA
manganese chloride results in decreased methylation of ABCC2 gene
CTD PMID:28801915 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc8 ATP binding cassette subfamily C member 8 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in increased expression of ABCC8 protein CTD PMID:32659473 NCBI chr 1:96,598,663...96,679,495
Ensembl chr 1:96,598,647...96,679,510
JBrowse link
G Abi2 abl-interactor 2 increases expression ISO manganese chloride results in increased expression of ABI2 mRNA CTD PMID:17175027 NCBI chr 9:61,856,379...61,904,029
Ensembl chr 9:61,827,139...61,905,699
JBrowse link
G Abitram actin binding transcription modulator increases expression EXP manganese chloride results in increased expression of ABITRAM mRNA CTD PMID:28801915 NCBI chr 5:71,505,853...71,524,224
Ensembl chr 5:71,505,813...71,511,890
JBrowse link
G Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 increases expression EXP manganese chloride results in increased expression of ACAP1 mRNA CTD PMID:28801915 NCBI chr10:54,605,323...54,619,472
Ensembl chr10:54,605,323...54,619,472
JBrowse link
G Ace angiotensin I converting enzyme increases expression EXP manganese chloride results in increased expression of ACE mRNA CTD PMID:28801915 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ache acetylcholinesterase increases activity
increases expression
multiple interactions
decreases activity
EXP
ISO
manganese chloride results in increased activity of ACHE protein
manganese chloride results in increased expression of ACHE mRNA
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased activity of ACHE protein]; [manganese chloride results in increased abundance of Manganese] which results in increased activity of ACHE protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased activity of ACHE protein]; Lycopene inhibits the reaction [manganese chloride results in increased activity of ACHE protein]; Silymarin inhibits the reaction [manganese chloride results in decreased activity of ACHE protein]; Silymarin inhibits the reaction [manganese chloride results in increased activity of ACHE protein]; Silymarin inhibits the reaction [manganese chloride results in increased expression of ACHE mRNA]
[manganese chloride results in increased abundance of Manganese] which results in decreased activity of ACHE protein; [manganese chloride results in increased abundance of Manganese] which results in increased activity of ACHE protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of ACHE mRNA alternative form
CTD PMID:20503066 PMID:22033861 PMID:22154916 PMID:22192907 PMID:30738988 More... NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Aco1 aconitase 1 increases activity EXP manganese chloride results in increased activity of ACO1 protein CTD PMID:15893546 PMID:16545456 PMID:16568477 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Aco2 aconitase 2 multiple interactions
decreases expression
decreases activity
ISO
EXP
ferric ammonium citrate inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]
manganese chloride results in decreased expression of ACO2 mRNA; manganese chloride results in decreased expression of ACO2 protein
Iron inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]
CTD PMID:9675333 PMID:16625280 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression EXP manganese chloride results in increased expression of ACOT2 mRNA CTD PMID:28801915 NCBI chr 6:103,611,744...103,619,404
Ensembl chr 6:103,611,544...103,619,245
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant increases expression
increases methylation
EXP manganese chloride results in increased expression of ACP5 mRNA
manganese chloride results in increased methylation of ACP5 gene
CTD PMID:22281203 PMID:28801915 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
JBrowse link
G Acr acrosin increases expression EXP manganese chloride results in increased expression of ACR mRNA CTD PMID:28801915 NCBI chr 7:120,636,581...120,644,474
Ensembl chr 7:120,638,321...120,644,474
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression ISO manganese chloride results in decreased expression of ACSL3 mRNA CTD PMID:15295902 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 decreases expression EXP manganese chloride results in decreased expression of ACSS2 mRNA CTD PMID:28801915 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle decreases expression EXP manganese chloride results in decreased expression of ACTA1 mRNA CTD PMID:26745496 NCBI chr19:51,883,713...51,886,725
Ensembl chr19:51,883,715...51,886,742
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression EXP manganese chloride results in increased expression of ACTA2 mRNA CTD PMID:28801915 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actb actin, beta decreases expression
increases expression
ISO manganese chloride results in decreased expression of ACTB protein
manganese chloride results in increased expression of ACTB mRNA
CTD PMID:20452446 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Acvrl1 activin A receptor like type 1 increases expression EXP manganese chloride results in increased expression of ACVRL1 mRNA CTD PMID:28801915 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591
JBrowse link
G Adam19 ADAM metallopeptidase domain 19 increases expression EXP manganese chloride results in increased expression of ADAM19 mRNA CTD PMID:28801915 NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 decreases expression EXP manganese chloride results in decreased expression of ADAMTS1 mRNA CTD PMID:28801915 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 decreases expression EXP manganese chloride results in decreased expression of ADAMTS5 mRNA CTD PMID:28801915 NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205
JBrowse link
G Adcy6 adenylate cyclase 6 increases expression EXP manganese chloride results in increased expression of ADCY6 mRNA CTD PMID:28801915 NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754
JBrowse link
G Add2 adducin 2 increases expression EXP manganese chloride results in increased expression of ADD2 mRNA CTD PMID:28801915 NCBI chr 4:118,444,594...118,538,505
Ensembl chr 4:118,497,416...118,538,505
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression EXP manganese chloride results in increased expression of ADIPOQ mRNA CTD PMID:28801915 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adm adrenomedullin increases expression
decreases expression
ISO
EXP
manganese chloride results in increased expression of ADM mRNA
manganese chloride results in decreased expression of ADM mRNA
CTD PMID:17175027 PMID:28801915 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Adora2a adenosine A2a receptor increases expression EXP manganese chloride results in increased expression of ADORA2A mRNA CTD PMID:28801915 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Aen apoptosis enhancing nuclease increases expression EXP manganese chloride results in increased expression of AEN mRNA CTD PMID:28801915 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
JBrowse link
G Aff1 ALF transcription elongation factor 1 increases expression EXP manganese chloride results in increased expression of AFF1 mRNA CTD PMID:28801915 NCBI chr14:5,861,188...6,024,196
Ensembl chr14:5,863,961...6,024,729
JBrowse link
G Afmid arylformamidase increases expression EXP manganese chloride results in increased expression of AFMID mRNA CTD PMID:28801915 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718
JBrowse link
G Afp alpha-fetoprotein decreases expression EXP manganese chloride results in decreased expression of AFP mRNA CTD PMID:26745496 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Ahnak2 AHNAK nucleoprotein 2 increases expression EXP manganese chloride results in increased expression of AHNAK2 mRNA CTD PMID:28801915 NCBI chr 6:131,830,668...131,876,311 JBrowse link
G Aicda activation-induced cytidine deaminase increases expression EXP manganese chloride results in increased expression of AICDA mRNA CTD PMID:28801915 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972
JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression ISO manganese chloride results in increased expression of AIF1 protein CTD PMID:28595911 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Akap7 A-kinase anchoring protein 7 decreases expression ISO manganese chloride results in decreased expression of AKAP7 mRNA CTD PMID:17175027 NCBI chr 1:20,087,190...20,217,799
Ensembl chr 1:20,087,373...20,217,797
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 increases expression EXP manganese chloride results in increased expression of AKR1B1 mRNA CTD PMID:22281203 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions
EXP
ISO
manganese chloride results in decreased phosphorylation of AKT1 protein
NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of AKT1 protein]
[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of AKT1 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of AKT1 protein]
CTD PMID:30040983 PMID:31676349 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alb albumin multiple interactions EXP [sodium arsenite co-treated with Cadmium Chloride co-treated with lead acetate co-treated with Mercuric Chloride co-treated with chromium trioxide co-treated with nickel chloride co-treated with manganese chloride co-treated with ferric chloride] results in decreased expression of ALB protein CTD PMID:17657459 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 increases expression EXP manganese chloride results in increased expression of ALDH18A1 mRNA CTD PMID:28801915 NCBI chr 1:239,375,657...239,407,967
Ensembl chr 1:239,375,669...239,407,890
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression EXP manganese chloride results in decreased expression of ALDH1A1 mRNA CTD PMID:28801915 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 increases expression EXP manganese chloride results in increased expression of ALDH4A1 mRNA CTD PMID:28801915 NCBI chr 5:151,880,002...151,905,491
Ensembl chr 5:151,830,701...151,925,345
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression EXP manganese chloride results in increased expression of ALDOA mRNA CTD PMID:22281203 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression EXP manganese chloride results in decreased expression of ALDOC mRNA CTD PMID:28801915 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
JBrowse link
G Alkal1 ALK and LTK ligand 1 increases expression EXP manganese chloride results in increased expression of ALKAL1 mRNA CTD PMID:28801915 NCBI chr 5:13,019,729...13,049,913
Ensembl chr 5:13,019,429...13,049,948
JBrowse link
G Amigo3 adhesion molecule with Ig like domain 3 increases expression EXP manganese chloride results in increased expression of AMIGO3 mRNA CTD PMID:28801915 NCBI chr 8:108,741,899...108,743,425
Ensembl chr 8:108,693,060...108,744,555
JBrowse link
G Angpt2 angiopoietin 2 decreases expression EXP manganese chloride results in decreased expression of ANGPT2 mRNA CTD PMID:26745496 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO manganese chloride results in increased expression of ANGPTL4 mRNA CTD PMID:17175027 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Ankrd28 ankyrin repeat domain 28 increases expression EXP manganese chloride results in increased expression of ANKRD28 mRNA CTD PMID:28801915 NCBI chr16:6,918,487...7,050,244
Ensembl chr16:6,914,336...7,050,249
JBrowse link
G Ano3 anoctamin 3 increases expression EXP manganese chloride results in increased expression of ANO3 mRNA CTD PMID:28801915 NCBI chr 3:97,235,671...97,550,090
Ensembl chr 3:97,238,354...97,550,154
JBrowse link
G Anxa3 annexin A3 decreases expression EXP manganese chloride results in decreased expression of ANXA3 mRNA CTD PMID:28801915 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Aopep aminopeptidase O decreases expression EXP manganese chloride results in decreased expression of AOPEP mRNA CTD PMID:28801915 NCBI chr17:1,811,922...2,127,316
Ensembl chr17:1,811,980...2,127,331
JBrowse link
G Ap3b2 adaptor related protein complex 3 subunit beta 2 increases expression ISO manganese chloride results in increased expression of AP3B2 mRNA CTD PMID:17175027 NCBI chr 1:135,412,580...135,445,191
Ensembl chr 1:135,412,580...135,445,191
JBrowse link
G Apbb3 amyloid beta precursor protein binding family B member 3 increases expression EXP manganese chloride results in increased expression of APBB3 mRNA CTD PMID:28801915 NCBI chr18:28,273,168...28,280,347
Ensembl chr18:28,270,545...28,280,094
JBrowse link
G Apc APC regulator of WNT signaling pathway decreases expression
increases methylation
ISO manganese chloride results in decreased expression of APC mRNA
manganese chloride results in increased methylation of APC gene
CTD PMID:27913844 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Apoa2 apolipoprotein A2 decreases expression EXP manganese chloride results in decreased expression of APOA2 mRNA CTD PMID:28801915 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apol2 apolipoprotein L, 2 increases expression ISO manganese chloride results in increased expression of APOL2 mRNA CTD PMID:17175027 NCBI chr 7:109,331,367...109,338,632
Ensembl chr 7:109,331,392...109,338,558
JBrowse link
G Apold1 apolipoprotein L domain containing 1 increases expression EXP manganese chloride results in increased expression of APOLD1 mRNA CTD PMID:28801915 NCBI chr 4:167,768,437...167,825,706
Ensembl chr 4:167,818,271...167,825,706
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) decreases expression EXP manganese chloride results in decreased expression of AQP3 mRNA CTD PMID:28801915 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
JBrowse link
G Areg amphiregulin increases expression EXP manganese chloride results in increased expression of AREG mRNA CTD PMID:28801915 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Arg1 arginase 1 increases expression
increases methylation
multiple interactions
EXP
ISO
manganese chloride results in increased expression of ARG1 mRNA
manganese chloride results in increased methylation of ARG1 gene
[manganese chloride results in increased abundance of Manganese] which results in increased expression of ARG1 mRNA
CTD PMID:28801915 PMID:34018660 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arhgap24 Rho GTPase activating protein 24 decreases expression EXP manganese chloride results in decreased expression of ARHGAP24 mRNA CTD PMID:28801915 NCBI chr14:6,800,631...7,184,001
Ensembl chr14:6,800,631...7,183,823
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO manganese chloride results in decreased expression of ARHGDIA mRNA CTD PMID:17175027 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 increases expression EXP manganese chloride results in increased expression of ARHGEF10 mRNA CTD PMID:28801915 NCBI chr16:74,647,147...74,738,784
Ensembl chr16:74,647,153...74,738,173
JBrowse link
G Arhgef16 Rho guanine nucleotide exchange factor 16 increases expression EXP manganese chloride results in increased expression of ARHGEF16 mRNA CTD PMID:28801915 NCBI chr 5:164,843,656...164,866,212
Ensembl chr 5:164,844,161...164,866,212
JBrowse link
G Arhgef4 Rho guanine nucleotide exchange factor 4 increases expression
increases methylation
ISO
EXP
manganese chloride results in increased expression of ARHGEF4 mRNA
manganese chloride results in increased methylation of ARHGEF4 gene
CTD PMID:17175027 PMID:28801915 NCBI chr 9:36,861,800...37,005,079
Ensembl chr 9:36,861,835...37,005,075
JBrowse link
G Arhgef6 Rac/Cdc42 guanine nucleotide exchange factor 6 increases expression EXP manganese chloride results in increased expression of ARHGEF6 mRNA CTD PMID:28801915 NCBI chr  X:135,145,447...135,264,636
Ensembl chr  X:135,146,786...135,275,304
JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor 7 decreases expression EXP manganese chloride results in decreased expression of ARHGEF7 mRNA CTD PMID:28801915 NCBI chr16:77,671,021...77,782,593
Ensembl chr16:77,671,023...77,782,697
JBrowse link
G Arid3a AT-rich interaction domain 3A increases expression EXP manganese chloride results in increased expression of ARID3A mRNA CTD PMID:28801915 NCBI chr 7:9,755,291...9,781,260
Ensembl chr 7:9,755,294...9,780,599
JBrowse link
G Arl4c ADP ribosylation factor like GTPase 4C increases methylation
increases expression
EXP manganese chloride results in increased methylation of ARL4C gene
manganese chloride results in increased expression of ARL4C mRNA
CTD PMID:28801915 NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO ARNT gene mutant form inhibits the reaction [manganese chloride results in increased secretion of VEGFA protein] CTD PMID:19263519 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Asb5 ankyrin repeat and SOCS box-containing 5 decreases expression EXP manganese chloride results in decreased expression of ASB5 mRNA CTD PMID:28801915 NCBI chr16:37,237,869...37,305,207
Ensembl chr16:37,235,405...37,278,109
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression EXP manganese chloride results in increased expression of ASNS mRNA CTD PMID:28801915 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Ass1 argininosuccinate synthase 1 increases expression EXP manganese chloride results in increased expression of ASS1 mRNA CTD PMID:28801915 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
JBrowse link
G Aste1 asteroid homolog 1 increases expression EXP manganese chloride results in increased expression of ASTE1 mRNA CTD PMID:28801915 NCBI chr 8:106,026,570...106,044,694
Ensembl chr 8:106,026,515...106,044,430
JBrowse link
G Atf1 activating transcription factor 1 increases phosphorylation
multiple interactions
EXP manganese chloride results in increased phosphorylation of ATF1 protein
SB 203580 inhibits the reaction [manganese chloride results in increased phosphorylation of ATF1 protein]
CTD PMID:16787641 NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670
JBrowse link
G Atf2 activating transcription factor 2 increases activity
increases phosphorylation
ISO manganese chloride results in increased activity of ATF2 protein
manganese chloride results in increased phosphorylation of ATF2 protein
CTD PMID:19084589 PMID:20152896 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression
EXP manganese chloride promotes the reaction [EIF2AK3 protein results in increased expression of ATF4 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of ATF4 mRNA]
manganese chloride results in increased expression of ATF4 mRNA; manganese chloride results in increased expression of ATF4 protein
CTD PMID:23934647 PMID:23948121 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf6 activating transcription factor 6 decreases expression
increases expression
ISO
EXP
manganese chloride results in decreased expression of ATF6 mRNA
manganese chloride results in increased expression of ATF6 protein
CTD PMID:17175027 PMID:25732873 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atm ATM serine/threonine kinase decreases expression ISO manganese chloride results in decreased expression of ATM mRNA CTD PMID:17175027 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 decreases expression EXP manganese chloride results in decreased expression of ATOH8 mRNA CTD PMID:26745496 PMID:28801915 NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 increases methylation EXP manganese chloride results in increased methylation of ATP2A3 gene CTD PMID:28801915 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748
JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 increases methylation
decreases expression
ISO manganese chloride results in increased methylation of ATP2B2 gene
manganese chloride results in decreased expression of ATP2B2 mRNA
CTD PMID:27913844 NCBI chr 4:146,896,332...147,140,665
Ensembl chr 4:146,896,332...147,140,665
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 increases expression EXP manganese chloride results in increased expression of ATP2B4 mRNA CTD PMID:28801915 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246
JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma decreases expression EXP manganese chloride results in decreased expression of ATP5C1 mRNA CTD PMID:22281203 NCBI chr17:68,423,927...68,446,169
Ensembl chr17:68,423,909...68,608,367
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A increases expression EXP manganese chloride results in increased expression of ATP6V1A mRNA CTD PMID:28801915 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
JBrowse link
G Atp6v1e2 ATPase H+ transporting V1 subunit E2 decreases expression EXP
ISO
manganese chloride results in decreased expression of ATP6V1E2 mRNA CTD PMID:28801915 NCBI chr 6:7,667,359...7,673,711
Ensembl chr 6:7,667,564...7,672,626
JBrowse link
G Atp7a ATPase copper transporting alpha decreases expression
affects localization
EXP manganese chloride results in decreased expression of ATP7A mRNA; manganese chloride results in decreased expression of ATP7A protein
manganese chloride affects the localization of ATP7A protein
CTD PMID:24614235 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Atp7b ATPase copper transporting beta affects localization
decreases expression
EXP manganese chloride affects the localization of ATP7B protein
manganese chloride results in decreased expression of ATP7B mRNA; manganese chloride results in decreased expression of ATP7B protein
CTD PMID:24614235 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
JBrowse link
G Atp8a1 ATPase phospholipid transporting 8A1 decreases expression ISO manganese chloride results in decreased expression of ATP8A1 mRNA CTD PMID:17175027 NCBI chr14:40,315,013...40,557,572
Ensembl chr14:40,315,049...40,554,611
JBrowse link
G Avil advillin decreases expression
increases methylation
EXP manganese chloride results in decreased expression of AVIL mRNA
manganese chloride results in increased methylation of AVIL gene
CTD PMID:28801915 NCBI chr 7:62,825,459...62,844,103
Ensembl chr 7:62,826,025...62,844,071
JBrowse link
G Axin2 axin 2 increases expression EXP manganese chloride results in increased expression of AXIN2 mRNA CTD PMID:28801915 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link
G Bach1 BTB domain and CNC homolog 1 increases expression EXP manganese chloride results in increased expression of BACH1 mRNA CTD PMID:28801915 NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
EXP
ISO
manganese chloride results in increased expression of BAX mRNA; manganese chloride results in increased expression of BAX protein
[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein; [Plant Extracts co-treated with manganese chloride] affects the expression of BAX protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein]; Estradiol inhibits the reaction [manganese chloride results in increased expression of BAX protein]; Tamoxifen inhibits the reaction [manganese chloride results in increased expression of BAX protein]
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased expression of BAX protein]; [manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein]; manganese chloride results in increased expression of and affects the localization of BAX protein
NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein]
CTD PMID:17623882 PMID:21704098 PMID:25732873 PMID:26064043 PMID:29183790 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
increases nitrosation
increases expression
EXP
ISO
manganese chloride results in decreased expression of BCL2 mRNA; manganese chloride results in decreased expression of BCL2 protein
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of BCL2 protein; [Plant Extracts co-treated with manganese chloride] affects the expression of BCL2 protein; Estradiol inhibits the reaction [manganese chloride results in decreased expression of BCL2 protein]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of BCL2 protein]
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in decreased expression of BCL2 protein]; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of BCL2 protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of BCL2 protein]; manganese chloride results in decreased expression of and affects the localization of BCL2 protein
manganese chloride results in increased nitrosation of BCL2 protein
corynoxine B inhibits the reaction [manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]]; manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]; manganese chloride results in increased expression of and results in decreased phosphorylation of BCL2 protein; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride results in increased expression of and results in decreased phosphorylation of BCL2 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride results in increased nitrosation of BCL2 protein]
manganese chloride results in increased expression of BCL2 mRNA
manganese chloride results in increased expression of BCL2 protein
CTD PMID:17623882 PMID:21704098 PMID:25732873 PMID:26064043 PMID:28801915 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression EXP manganese chloride results in decreased expression of BCL2L1 protein CTD PMID:27107493 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression
decreases expression
EXP manganese chloride results in increased expression of BCL2L11 protein
manganese chloride results in decreased expression of BCL2L11 mRNA
CTD PMID:25732873 PMID:28801915 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bcl6b BCL6B, transcription repressor increases expression EXP manganese chloride results in increased expression of BCL6B mRNA CTD PMID:28801915 NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974
JBrowse link
G Bdkrb2 bradykinin receptor B2 increases expression EXP manganese chloride results in increased expression of BDKRB2 mRNA CTD PMID:28801915 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression
increases expression
increases methylation
multiple interactions
ISO
EXP
manganese chloride results in decreased expression of BDNF mRNA
manganese chloride results in increased expression of BDNF mRNA
manganese chloride results in increased methylation of BDNF gene
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of BDNF protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of BDNF mRNA; CREB1 protein affects the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BDNF mRNA]
CTD PMID:25698507 PMID:28801915 PMID:30951808 PMID:32659473 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Becn1 beclin 1 increases expression
multiple interactions
decreases expression
affects expression
EXP
ISO
manganese chloride results in increased expression of BECN1 protein
wortmannin inhibits the reaction [manganese chloride results in increased expression of BECN1 protein]
manganese chloride results in decreased expression of BECN1 protein
corynoxine B affects the reaction [manganese chloride affects the reaction [HMGB1 protein binds to BECN1 protein]]; corynoxine B inhibits the reaction [manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]]; manganese chloride affects the reaction [HMGB1 protein binds to BECN1 protein]; manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]]
manganese chloride affects the expression of BECN1 protein
CTD PMID:23604964 PMID:28856835 PMID:30578841 PMID:30672645 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression EXP manganese chloride results in increased expression of BHLHE40 mRNA CTD PMID:28801915 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
JBrowse link
G Bid BH3 interacting domain death agonist increases cleavage
increases expression
multiple interactions
EXP manganese chloride results in increased cleavage of BID protein
manganese chloride results in increased expression of BID protein; manganese chloride results in increased expression of BID protein modified form
bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased expression of BID protein]; pepstatin inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; pepstatin inhibits the reaction [manganese chloride results in increased expression of BID protein]
CTD PMID:21704098 PMID:28378122 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression
EXP Lithium Chloride inhibits the reaction [manganese chloride results in decreased expression of BIRC5 mRNA] CTD PMID:24464479 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 increases expression EXP manganese chloride results in increased expression of BIRC7 mRNA CTD PMID:28801915 NCBI chr 3:168,047,824...168,052,606
Ensembl chr 3:168,047,824...168,052,606
JBrowse link
G Bloc1s3 biogenesis of lysosomal organelles complex-1, subunit 3 increases expression EXP manganese chloride results in increased expression of BLOC1S3 mRNA CTD PMID:28801915 NCBI chr 1:79,155,914...79,158,326
Ensembl chr 1:79,155,693...79,158,505
JBrowse link
G Blvra biliverdin reductase A increases expression EXP manganese chloride results in increased expression of BLVRA mRNA CTD PMID:22281203 NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033
JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 decreases expression EXP manganese chloride results in decreased expression of ARNTL mRNA CTD PMID:28511934 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Bmf Bcl2 modifying factor decreases expression EXP manganese chloride results in decreased expression of BMF mRNA CTD PMID:28801915 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression ISO manganese chloride results in increased expression of BMP4 mRNA CTD PMID:17467022 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Bnip3 BCL2 interacting protein 3 multiple interactions
affects response to substance
ISO [N-(3-(aminomethyl)benzyl)acetamidine results in decreased activity of NOS2 protein] inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; Acetylcysteine inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; BNIP3 protein affects the reaction [manganese chloride affects the localization of CYCS protein]; Cycloheximide inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; Dactinomycin inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; Glutathione inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; manganese chloride results in increased expression of and affects the localization of BNIP3 protein
BNIP3 protein affects the susceptibility to manganese chloride
CTD PMID:19442826 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bpifb6 BPI fold containing family B, member 6 increases expression EXP manganese chloride results in increased expression of BPIFB6 mRNA CTD PMID:28801915 NCBI chr 3:142,383,701...142,395,308
Ensembl chr 3:142,381,374...142,395,308
JBrowse link
G Bsn bassoon (presynaptic cytomatrix protein) increases expression EXP manganese chloride results in increased expression of BSN mRNA CTD PMID:28801915 NCBI chr 8:108,784,849...108,875,819
Ensembl chr 8:108,788,542...108,875,819
JBrowse link
G Btnl5 butyrophilin-like 5 decreases expression EXP manganese chloride results in decreased expression of BTNL5 mRNA CTD PMID:28801915 NCBI chr20:4,366,780...4,376,385
Ensembl chr20:4,365,793...4,376,385
JBrowse link
G Btnl7 butyrophilin-like 7 decreases expression EXP manganese chloride results in decreased expression of BTNL7 mRNA CTD PMID:28801915 NCBI chr20:4,301,078...4,313,522
Ensembl chr20:4,301,854...4,313,274
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO manganese chloride results in decreased expression of BUB1 mRNA CTD PMID:17175027 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G C1qtnf4 C1q and TNF related 4 increases expression EXP manganese chloride results in increased expression of C1QTNF4 mRNA CTD PMID:28801915 NCBI chr 3:76,854,368...76,872,991
Ensembl chr 3:76,857,735...76,874,139
JBrowse link
G C2cd4b C2 calcium-dependent domain containing 4B increases expression EXP manganese chloride results in increased expression of C2CD4B mRNA CTD PMID:28801915 NCBI chr 8:68,372,793...68,396,477
Ensembl chr 8:68,384,847...68,396,328
JBrowse link
G C4bpa complement component 4 binding protein, alpha decreases expression EXP manganese chloride results in decreased expression of C4BPA mRNA CTD PMID:28801915 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205
JBrowse link
G C5 complement C5 decreases expression EXP manganese chloride results in decreased expression of C5 mRNA CTD PMID:28801915 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
JBrowse link
G Cables1 Cdk5 and Abl enzyme substrate 1 decreases expression EXP manganese chloride results in decreased expression of CABLES1 mRNA CTD PMID:28801915 NCBI chr18:3,076,556...3,181,183
Ensembl chr18:3,075,524...3,181,181
JBrowse link
G Calcoco2 calcium binding and coiled-coil domain 2 increases expression ISO manganese chloride results in increased expression of CALCOCO2 mRNA CTD PMID:17175027 NCBI chr10:81,055,467...81,069,298 JBrowse link
G Cald1 caldesmon 1 increases expression EXP manganese chloride results in increased expression of CALD1 mRNA CTD PMID:28801915 NCBI chr 4:63,265,781...63,446,936
Ensembl chr 4:63,265,942...63,446,932
JBrowse link
G Caly calcyon neuron-specific vesicular protein increases expression EXP manganese chloride results in increased expression of CALY mRNA CTD PMID:28801915 NCBI chr 1:194,862,671...194,873,861
Ensembl chr 1:194,862,672...194,873,551
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 increases expression ISO manganese chloride results in increased expression of CAMKK2 mRNA CTD PMID:15295902 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279
JBrowse link
G Camkv CaM kinase-like vesicle-associated decreases expression EXP manganese chloride results in decreased expression of CAMKV mRNA CTD PMID:28801915 NCBI chr 8:108,626,821...108,641,169
Ensembl chr 8:108,626,821...108,641,169
JBrowse link
G Camp cathelicidin antimicrobial peptide increases expression EXP manganese chloride results in increased expression of CAMP mRNA CTD PMID:28801915 NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543
JBrowse link
G Camta2 calmodulin binding transcription activator 2 increases expression EXP manganese chloride results in increased expression of CAMTA2 mRNA CTD PMID:28801915 NCBI chr10:55,383,450...55,401,838
Ensembl chr10:55,383,450...55,401,558
JBrowse link
G Capn5 calpain 5 increases expression EXP manganese chloride results in increased expression of CAPN5 mRNA CTD PMID:28801915 NCBI chr 1:152,416,252...152,472,923
Ensembl chr 1:152,416,252...152,472,923
JBrowse link
G Car5b carbonic anhydrase 5B decreases expression EXP manganese chloride results in decreased expression of CAR5B mRNA CTD PMID:28801915 NCBI chr  X:30,474,697...30,534,797
Ensembl chr  X:30,474,784...30,533,837
JBrowse link
G Car8 carbonic anhydrase 8 increases expression EXP manganese chloride results in increased expression of CAR8 mRNA CTD PMID:26745496 NCBI chr 5:21,302,940...21,402,395
Ensembl chr 5:21,305,383...21,402,374
JBrowse link
G Card14 caspase recruitment domain family, member 14 increases methylation ISO manganese chloride results in increased methylation of CARD14 gene CTD PMID:27913844 NCBI chr10:104,572,059...104,601,606
Ensembl chr10:104,566,424...104,601,905
JBrowse link
G Card9 caspase recruitment domain family, member 9 decreases expression EXP manganese chloride results in decreased expression of CARD9 mRNA CTD PMID:28801915 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
JBrowse link
G Casp12 caspase 12 multiple interactions
increases expression
increases cleavage
ISO
EXP
Deferoxamine promotes the reaction [manganese chloride results in increased cleavage of and results in increased activity of CASP12 protein]; manganese chloride results in increased cleavage of and results in increased activity of CASP12 protein
manganese chloride results in increased expression of CASP12 mRNA; manganese chloride results in increased expression of CASP12 protein
SNCA protein promotes the reaction [manganese chloride results in increased expression of CASP12 protein]
manganese chloride results in increased cleavage of CASP12 protein
Plant Extracts inhibits the reaction [manganese chloride results in increased cleavage of CASP12 protein]
CTD PMID:23764342 PMID:23934647 PMID:23948121 PMID:25732873 PMID:26064043 More... NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp2 caspase 2 increases expression EXP manganese chloride results in increased expression of CASP2 mRNA CTD PMID:28801915 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
increases expression
increases activity
increases methylation
ISO
EXP
manganese chloride results in increased cleavage of CASP3 protein
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased expression of CASP3 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of CASP3 protein; Acetylcysteine inhibits the reaction [manganese chloride results in increased expression of CASP3 protein modified form]; bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of CASP3 protein]; GW 506033X inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein]; Lithium Chloride inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]; pepstatin inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [manganese chloride results in increased expression of CASP3 protein]; Quercetin inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]; rhodioloside inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein]; U 0126 inhibits the reaction [manganese chloride results in increased expression of CASP3 mRNA]; U 0126 inhibits the reaction [manganese chloride results in increased expression of CASP3 protein]
manganese chloride results in increased expression of CASP3 mRNA; manganese chloride results in increased expression of CASP3 protein; manganese chloride results in increased expression of CASP3 protein modified form
[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein; Plant Extracts inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; PRNP protein inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]
Deferoxamine promotes the reaction [manganese chloride results in increased activity of CASP3 protein]; SNCA protein inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]
manganese chloride results in increased methylation of CASP3 gene
CTD PMID:16787641 PMID:17483122 PMID:18178165 PMID:19815061 PMID:23764342 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 increases expression EXP manganese chloride results in increased expression of CASP4 mRNA CTD PMID:28801915 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp8 caspase 8 increases cleavage
multiple interactions
EXP manganese chloride results in increased cleavage of CASP8 protein
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein]; pepstatin inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein]
CTD PMID:21704098 PMID:28378122 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions
increases cleavage
ISO
EXP
manganese chloride results in increased activity of CASP9 protein
PRNP protein inhibits the reaction [manganese chloride results in increased activity of CASP9 protein]
SNCA protein inhibits the reaction [manganese chloride results in increased activity of CASP9 protein]
manganese chloride results in increased cleavage of CASP9 protein
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein]; pepstatin inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein]
CTD PMID:16787641 PMID:17483122 PMID:21704098 PMID:25416158 PMID:28378122 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase decreases activity
multiple interactions
decreases expression
EXP
ISO
manganese chloride results in decreased activity of CAT protein
[manganese chloride results in increased abundance of Manganese] which results in decreased activity of CAT protein; [Plant Extracts co-treated with manganese chloride] results in increased expression of CAT protein; Estradiol inhibits the reaction [manganese chloride results in decreased expression of CAT protein]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of CAT protein]
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in decreased activity of CAT protein]; [manganese chloride results in increased abundance of Manganese] which results in decreased activity of CAT protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased activity of CAT protein]; Quercetin inhibits the reaction [manganese chloride results in decreased activity of CAT protein]; Silymarin inhibits the reaction [manganese chloride results in decreased activity of CAT protein]
CTD PMID:20503066 PMID:22033861 PMID:22192907 PMID:26064043 PMID:28040552 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Catip ciliogenesis associated TTC17 interacting protein increases expression EXP manganese chloride results in increased expression of CATIP mRNA CTD PMID:28801915 NCBI chr 9:75,945,933...75,953,618
Ensembl chr 9:75,945,961...75,953,607
JBrowse link
G Catsperd cation channel sperm associated auxiliary subunit delta increases expression EXP manganese chloride results in increased expression of CATSPERD mRNA CTD PMID:28801915 NCBI chr 9:1,459,967...1,498,342
Ensembl chr 9:1,460,001...1,498,344
JBrowse link
G Cav2 caveolin 2 decreases expression EXP manganese chloride results in decreased expression of CAV2 mRNA CTD PMID:28801915 NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244
JBrowse link
G Cbarp CACN subunit beta associated regulatory protein increases expression EXP manganese chloride results in increased expression of DOS mRNA CTD PMID:28801915 NCBI chr 7:9,566,637...9,575,204
Ensembl chr 7:9,566,364...9,575,204
JBrowse link
G Cbs cystathionine beta synthase decreases expression EXP manganese chloride results in decreased expression of CBS mRNA CTD PMID:28801915 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
G Ccdc15 coiled-coil domain containing 15 increases expression EXP manganese chloride results in increased expression of CCDC15 mRNA CTD PMID:28801915 NCBI chr 8:36,991,147...37,068,849
Ensembl chr 8:36,998,867...37,068,919
JBrowse link
G Ccdc175 coiled-coil domain containing 175 increases expression EXP manganese chloride results in increased expression of CCDC175 mRNA CTD PMID:28801915 NCBI chr 6:90,661,948...90,745,015
Ensembl chr 6:90,662,269...90,744,963
JBrowse link
G Ccdc96 coiled-coil domain containing 96 increases expression EXP manganese chloride results in increased expression of CCDC96 mRNA CTD PMID:28801915 NCBI chr14:74,276,568...74,279,072
Ensembl chr14:74,276,960...74,278,888
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 increases expression EXP manganese chloride results in increased expression of CCL17 mRNA CTD PMID:28801915 NCBI chr19:10,202,317...10,203,768
Ensembl chr19:10,202,128...10,203,819
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 increases expression EXP manganese chloride results in increased expression of CCL19 mRNA CTD PMID:28801915 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases secretion
ISO
EXP
manganese chloride inhibits the reaction [CCL2 protein results in increased expression of ICAM1 protein]; manganese chloride inhibits the reaction [Glucose results in increased secretion of CCL2 protein]
manganese chloride results in decreased secretion of CCL2 protein
CTD PMID:23329836 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression EXP manganese chloride results in increased expression of CCL5 mRNA CTD PMID:28801915 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO
EXP
manganese chloride results in increased expression of CCL7 mRNA CTD PMID:17175027 PMID:28801915 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression
increases methylation
ISO
EXP
manganese chloride results in increased expression of CCN2 mRNA
manganese chloride results in increased methylation of CCN2 gene
CTD PMID:17467022 PMID:28801915 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccna1 cyclin A1 increases expression EXP manganese chloride results in increased expression of CCNA1 mRNA CTD PMID:26745496 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB1 mRNA; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB1 protein CTD PMID:34822792 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 decreases expression
multiple interactions
ISO manganese chloride results in decreased expression of CCNB2 mRNA
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB2 mRNA; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB2 protein; YTHDC2 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB2 mRNA]; YTHDC2 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB2 protein]
CTD PMID:17175027 PMID:34822792 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccng1 cyclin G1 increases expression EXP manganese chloride results in increased expression of CCNG1 mRNA CTD PMID:28801915 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cd28 Cd28 molecule multiple interactions ISO [manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein; manganese chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CD28 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein] CTD PMID:8662792 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression EXP manganese chloride results in increased expression of CD44 mRNA CTD PMID:28801915 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd48 Cd48 molecule increases expression ISO manganese chloride results in increased expression of CD48 mRNA CTD PMID:17175027 NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142
JBrowse link
G Cd6 Cd6 molecule decreases expression EXP manganese chloride results in decreased expression of CD6 mRNA CTD PMID:28801915 NCBI chr 1:207,442,873...207,481,703
Ensembl chr 1:207,442,877...207,481,634
JBrowse link
G Cd74 CD74 molecule increases expression EXP manganese chloride results in increased expression of CD74 mRNA CTD PMID:28801915 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cd86 CD86 molecule increases expression ISO manganese chloride results in increased expression of CD86 protein CTD PMID:15737199 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cd8b CD8b molecule increases expression ISO manganese chloride results in increased expression of CD8B mRNA; manganese chloride results in increased expression of CD8B1 mRNA CTD PMID:17175027 NCBI chr 4:103,312,596...103,328,523
Ensembl chr 4:103,312,578...103,328,553
JBrowse link
G Cdc42ep3 CDC42 effector protein 3 increases expression EXP manganese chloride results in increased expression of CDC42EP3 mRNA CTD PMID:28801915 NCBI chr 6:15,710,894...15,731,366
Ensembl chr 6:15,708,730...15,732,721
JBrowse link
G Cdhr4 cadherin-related family member 4 decreases expression EXP manganese chloride results in decreased expression of CDHR4 mRNA CTD PMID:28801915 NCBI chr 8:108,682,594...108,690,358
Ensembl chr 8:108,682,613...108,690,367
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
affects localization
EXP Cycloheximide inhibits the reaction [manganese chloride results in increased expression of CDKN1A protein]
manganese chloride results in increased expression of CDKN1A mRNA; manganese chloride results in increased expression of CDKN1A protein
manganese chloride affects the localization of CDKN1A protein
CTD PMID:22542671 PMID:28801915 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression EXP manganese chloride results in decreased expression of CDKN1C mRNA CTD PMID:28801915 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B increases expression EXP manganese chloride results in increased expression of CDKN2B mRNA CTD PMID:28801915 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C decreases expression ISO manganese chloride results in decreased expression of CDKN2C mRNA CTD PMID:17175027 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO manganese chloride results in decreased expression of CDKN3 mRNA CTD PMID:17175027 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Cdnf cerebral dopamine neurotrophic factor increases expression EXP manganese chloride results in increased expression of CDNF mRNA CTD PMID:28801915 NCBI chr17:74,714,564...74,728,639
Ensembl chr17:74,713,564...74,728,639
JBrowse link
G Cdyl2 chromodomain Y-like 2 increases expression EXP manganese chloride results in increased expression of CDYL2 mRNA CTD PMID:28801915 NCBI chr19:44,591,734...44,783,258
Ensembl chr19:44,597,459...44,783,022
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO manganese chloride results in increased expression of CEBPD mRNA CTD PMID:17175027 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Celsr1 cadherin, EGF LAG seven-pass G-type receptor 1 increases expression ISO manganese chloride results in increased expression of CELSR1 mRNA CTD PMID:17175027 NCBI chr 7:116,987,616...117,125,035
Ensembl chr 7:116,987,605...117,125,164
JBrowse link
G Cep112 centrosomal protein 112 increases expression EXP manganese chloride results in increased expression of CEP112 mRNA CTD PMID:28801915 NCBI chr10:93,366,059...93,833,133
Ensembl chr10:93,366,136...93,833,131
JBrowse link
G Cep128 centrosomal protein 128 decreases expression ISO manganese chloride results in decreased expression of CEP128 mRNA CTD PMID:17175027 NCBI chr 6:109,951,009...110,328,686
Ensembl chr 6:109,951,061...110,328,713
JBrowse link
G Cers1 ceramide synthase 1 increases expression EXP manganese chloride results in increased expression of CERS1 mRNA CTD PMID:28801915 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,104,466...19,112,519
JBrowse link
G Cers6 ceramide synthase 6 increases expression EXP manganese chloride results in increased expression of CERS6 mRNA CTD PMID:28801915 NCBI chr 3:53,630,636...53,879,692
Ensembl chr 3:53,630,959...53,876,848
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression EXP manganese chloride results in increased expression of CFLAR mRNA CTD PMID:28801915 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cftr CF transmembrane conductance regulator increases expression EXP manganese chloride results in increased expression of CFTR mRNA CTD PMID:28801915 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 increases expression EXP manganese chloride results in increased expression of CGREF1 mRNA CTD PMID:28801915 NCBI chr 6:25,431,846...25,443,853
Ensembl chr 6:25,431,799...25,443,852
JBrowse link
G Ch25h cholesterol 25-hydroxylase increases expression EXP manganese chloride results in increased expression of CH25H mRNA CTD PMID:28801915 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195
JBrowse link
G Chat choline O-acetyltransferase multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased activity of CHAT protein CTD PMID:30738988 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Chchd2l2 coiled-coil-helix-coiled-coil-helix domain containing protein 2-like 2 increases expression EXP manganese chloride results in increased expression of ZBED5 mRNA CTD PMID:28801915 NCBI chr12:26,807,652...26,813,706
Ensembl chr12:26,807,600...26,813,664
JBrowse link
G Chml CHM like Rab escort protein increases expression EXP manganese chloride results in increased expression of CHML mRNA CTD PMID:28801915 NCBI chr13:87,613,610...87,615,475
Ensembl chr13:87,589,298...87,619,862
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit decreases expression ISO manganese chloride results in decreased expression of CHRNA7 protein CTD PMID:25874029 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Chst10 carbohydrate sulfotransferase 10 increases expression EXP manganese chloride results in increased expression of CHST10 mRNA CTD PMID:28801915 NCBI chr 9:41,092,805...41,122,737
Ensembl chr 9:41,092,808...41,122,503
JBrowse link
G Chst5 carbohydrate sulfotransferase 5 increases expression EXP manganese chloride results in increased expression of CHST5 mRNA CTD PMID:28801915 NCBI chr19:39,860,729...39,881,019
Ensembl chr19:39,860,501...39,881,064
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions
increases phosphorylation
EXP 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride results in increased phosphorylation of CHUK protein] CTD PMID:22245093 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator increases expression EXP manganese chloride results in increased expression of CIITA mRNA CTD PMID:28801915 NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440
JBrowse link
G Cish cytokine inducible SH2-containing protein increases expression EXP manganese chloride results in increased expression of CISH mRNA CTD PMID:28801915 NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250
JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 decreases expression EXP manganese chloride results in decreased expression of CITED1 mRNA CTD PMID:28801915 NCBI chr  X:67,350,376...67,355,072
Ensembl chr  X:67,350,373...67,355,162
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression ISO manganese chloride results in decreased expression of CKS2 mRNA CTD PMID:17175027 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Cldn23 claudin 23 increases expression EXP manganese chloride results in increased expression of CLDN23 mRNA CTD PMID:26745496 NCBI chr16:56,413,677...56,415,401
Ensembl chr16:56,413,381...56,415,523
JBrowse link
G Cldn4 claudin 4 increases expression EXP manganese chloride results in increased expression of CLDN4 mRNA CTD PMID:28801915 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
JBrowse link
G Cldn9 claudin 9 decreases expression EXP manganese chloride results in decreased expression of CLDN9 mRNA CTD PMID:28801915 NCBI chr10:12,714,137...12,715,568 JBrowse link
G Clec4f C-type lectin domain family 4, member F increases methylation EXP manganese chloride results in increased methylation of CLEC4F gene CTD PMID:28801915 NCBI chr 4:116,129,023...116,138,744
Ensembl chr 4:116,129,023...116,138,775
JBrowse link
G Clock clock circadian regulator decreases expression EXP manganese chloride results in decreased expression of CLOCK mRNA CTD PMID:28511934 NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400
JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 increases expression
increases methylation
EXP manganese chloride results in increased expression of CMPK2 mRNA
manganese chloride results in increased methylation of CMPK2 gene
CTD PMID:28801915 NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183
JBrowse link
G Cnksr1 connector enhancer of kinase suppressor of Ras 1 increases expression EXP manganese chloride results in increased expression of CNKSR1 mRNA CTD PMID:28801915 NCBI chr 5:146,447,495...146,458,332
Ensembl chr 5:146,447,497...146,458,212
JBrowse link
G Cnot2 CCR4-NOT transcription complex, subunit 2 decreases expression ISO manganese chloride results in decreased expression of CNOT2 mRNA CTD PMID:17175027 NCBI chr 7:52,130,444...52,222,338
Ensembl chr 7:52,130,441...52,223,575
JBrowse link
G Cnot6l CCR4-NOT transcription complex, subunit 6-like increases expression ISO manganese chloride results in increased expression of CNOT6L mRNA CTD PMID:17175027 NCBI chr14:13,410,501...13,502,511
Ensembl chr14:13,411,281...13,498,203
JBrowse link
G Cntn4 contactin 4 decreases expression ISO manganese chloride results in decreased expression of CNTN4 mRNA CTD PMID:15295902 NCBI chr 4:138,624,584...139,622,499
Ensembl chr 4:139,099,152...139,621,090
JBrowse link
G Col12a1 collagen type XII alpha 1 chain decreases expression ISO manganese chloride results in decreased expression of COL12A1 mRNA CTD PMID:17175027 NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686
JBrowse link
G Col15a1 collagen type XV alpha 1 chain increases expression EXP manganese chloride results in increased expression of COL15A1 mRNA CTD PMID:28801915 NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591
JBrowse link
G Col17a1 collagen type XVII alpha 1 chain increases expression EXP manganese chloride results in increased expression of COL17A1 mRNA CTD PMID:28801915 NCBI chr 1:246,530,589...246,577,632
Ensembl chr 1:246,531,367...246,577,632
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain increases expression ISO manganese chloride results in increased expression of COL18A1 mRNA CTD PMID:17467022 NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593
JBrowse link
G Col4a5 collagen type IV alpha 5 chain decreases expression EXP manganese chloride results in decreased expression of COL4A5 mRNA CTD PMID:28801915 NCBI chr  X:105,118,762...105,322,699
Ensembl chr  X:105,118,820...105,322,692
JBrowse link
G Col5a2 collagen type V alpha 2 chain increases expression EXP manganese chloride results in increased expression of COL5A2 mRNA CTD PMID:28801915 NCBI chr 9:47,448,736...47,598,396
Ensembl chr 9:47,448,736...47,598,154
JBrowse link
G Col6a1 collagen type VI alpha 1 chain increases expression EXP manganese chloride results in increased expression of COL6A1 mRNA CTD PMID:28801915 NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597
JBrowse link
G Col7a1 collagen type VII alpha 1 chain increases expression EXP manganese chloride results in increased expression of COL7A1 mRNA CTD PMID:28801915 NCBI chr 8:109,604,877...109,637,252
Ensembl chr 8:109,604,861...109,637,252
JBrowse link
G Col8a1 collagen type VIII alpha 1 chain increases expression EXP manganese chloride results in increased expression of COL8A1 mRNA CTD PMID:28801915 NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424
JBrowse link
G Colec10 collectin subfamily member 10 decreases expression EXP manganese chloride results in decreased expression of COLEC10 mRNA CTD PMID:28801915 NCBI chr 7:85,744,895...85,806,368
Ensembl chr 7:85,744,895...85,805,675
JBrowse link
G Colec12 collectin sub-family member 12 decreases expression EXP manganese chloride results in decreased expression of COLEC12 mRNA CTD PMID:28801915 NCBI chr18:732,950...920,620
Ensembl chr18:732,950...920,618
JBrowse link
G Copg2 COPI coat complex subunit gamma 2 increases expression EXP manganese chloride results in increased expression of COPG2 mRNA CTD PMID:28801915 NCBI chr 4:59,366,086...59,501,591
Ensembl chr 4:59,366,086...59,501,618
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 increases expression EXP manganese chloride results in increased expression of COX6A2 mRNA CTD PMID:28801915 NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274
JBrowse link
G Cplx2 complexin 2 increases expression EXP manganese chloride results in increased expression of CPLX2 mRNA CTD PMID:28801915 NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855
JBrowse link
G Cpm carboxypeptidase M decreases expression ISO manganese chloride results in decreased expression of CPM mRNA CTD PMID:17175027 NCBI chr 7:53,225,647...53,286,220
Ensembl chr 7:53,225,696...53,286,220
JBrowse link
G Cracdl CRACD like increases expression EXP manganese chloride results in increased expression of CRACDL mRNA CTD PMID:28801915 NCBI chr 9:39,834,321...39,950,763
Ensembl chr 9:39,834,833...39,951,086
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation
multiple interactions
EXP
ISO
manganese chloride results in increased phosphorylation of CREB1 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein; CREB1 protein affects the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BDNF mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein]; SB 203580 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein]; SB 203580 inhibits the reaction [manganese chloride results in increased phosphorylation of CREB1 protein]
[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of CREB1 protein; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of CREB1 protein]
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of CREB1 protein; NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of CREB1 protein]
CTD PMID:16787641 PMID:30951808 PMID:31676349 PMID:32659473 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crebl2 cAMP responsive element binding protein-like 2 increases expression EXP manganese chloride results in increased expression of CREBL2 mRNA CTD PMID:28801915 NCBI chr 4:167,673,359...167,699,299
Ensembl chr 4:167,673,315...167,699,292
JBrowse link
G Crk CRK proto-oncogene, adaptor protein increases expression EXP manganese chloride results in increased expression of CRK mRNA CTD PMID:28801915 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406
JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression EXP manganese chloride results in decreased expression of CRY1 mRNA CTD PMID:28511934 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
JBrowse link
G Cryaa crystallin, alpha A increases methylation EXP manganese chloride results in increased methylation of CRYAA gene CTD PMID:28801915 NCBI chr20:9,783,605...9,787,351
Ensembl chr20:9,783,605...9,787,349
JBrowse link
G Cryab crystallin, alpha B decreases expression EXP manganese chloride results in decreased expression of CRYAB mRNA CTD PMID:28801915 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Cryba4 crystallin, beta A4 increases expression EXP manganese chloride results in increased expression of CRYBA4 mRNA CTD PMID:28801915 NCBI chr12:44,378,734...44,393,226
Ensembl chr12:44,378,737...44,393,221
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions
increases expression
ISO
EXP
manganese chloride promotes the reaction [SNCA protein results in increased expression of CSF2 mRNA]
manganese chloride results in increased expression of CSF2 mRNA
CTD PMID:28539244 PMID:28801915 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csf3 colony stimulating factor 3 increases expression EXP manganese chloride results in increased expression of CSF3 mRNA CTD PMID:28801915 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 increases expression
increases methylation
EXP manganese chloride results in increased expression of CSPG4 mRNA
manganese chloride results in increased methylation of CSPG4 gene
CTD PMID:28801915 NCBI chr 8:57,264,962...57,300,010
Ensembl chr 8:57,264,962...57,300,010
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 increases expression EXP manganese chloride results in increased expression of CSRP3 mRNA CTD PMID:26745496 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
JBrowse link
G Cstf2 cleavage stimulation factor subunit 2 increases expression EXP manganese chloride results in increased expression of CSTF2 mRNA CTD PMID:28801915 NCBI chr  X:97,253,559...97,279,476
Ensembl chr  X:97,253,586...97,279,476
JBrowse link
G Ctnna1 catenin alpha 1 decreases expression ISO manganese chloride results in decreased expression of CTNNA1 mRNA CTD PMID:17175027 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression
multiple interactions
ISO
EXP
manganese chloride results in decreased expression of CTNNB1 mRNA
Lithium Chloride inhibits the reaction [manganese chloride results in decreased expression of CTNNB1 protein]
CTD PMID:17175027 PMID:24464479 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctnnd1 catenin delta 1 increases expression EXP manganese chloride results in increased expression of CTNND1 mRNA CTD PMID:28801915 NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516
JBrowse link
G Ctsd cathepsin D increases expression
affects localization
EXP manganese chloride results in increased expression of CTSD protein
manganese chloride affects the localization of CTSD protein
CTD PMID:28378122 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Ctsw cathepsin W increases expression EXP manganese chloride results in increased expression of CTSW mRNA CTD PMID:28801915 NCBI chr 1:202,772,395...202,777,021
Ensembl chr 1:202,772,572...202,775,964
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression EXP manganese chloride results in increased expression of CX3CL1 mRNA CTD PMID:28801915 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases methylation
increases expression
EXP manganese chloride results in increased methylation of CXCL1 gene
manganese chloride results in increased expression of CXCL1 mRNA
CTD PMID:28801915 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO manganese chloride results in increased expression of CXCL10 mRNA CTD PMID:27427241 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression EXP manganese chloride results in decreased expression of CXCL12 mRNA CTD PMID:28801915 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 increases expression ISO manganese chloride results in increased expression of CXCL14 mRNA CTD PMID:17175027 NCBI chr17:8,317,933...8,325,956
Ensembl chr17:8,317,933...8,324,839
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO
EXP
manganese chloride results in increased expression of CXCL2 mRNA CTD PMID:17175027 PMID:28801915 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression EXP manganese chloride results in increased expression of CXCL3 mRNA CTD PMID:28801915 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 increases expression ISO manganese chloride results in increased expression of CXCL6 mRNA CTD PMID:17175027 NCBI chr14:17,310,089...17,312,303
Ensembl chr14:17,310,426...17,313,093
JBrowse link
G Cxxc1 CXXC finger protein 1 increases methylation
decreases expression
ISO manganese chloride results in increased methylation of CXXC1 gene
manganese chloride results in decreased expression of CXXC1 mRNA
CTD PMID:27913844 NCBI chr18:67,813,185...67,818,556
Ensembl chr18:67,813,206...67,818,551
JBrowse link
G Cycs cytochrome c, somatic multiple interactions
affects localization
ISO BNIP3 protein affects the reaction [manganese chloride affects the localization of CYCS protein]; Cyclosporine inhibits the reaction [manganese chloride affects the localization of CYCS protein]
SNCA protein inhibits the reaction [manganese chloride affects the localization of CYCS protein]
CTD PMID:19442826 PMID:25416158 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression
increases expression
EXP manganese chloride inhibits the reaction [CYP11A1 protein results in increased chemical synthesis of Progesterone]
manganese chloride results in decreased expression of CYP11A1 protein
manganese chloride results in increased expression of CYP11A1 mRNA
CTD PMID:12699903 PMID:25981801 PMID:28801915 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases expression EXP manganese chloride results in decreased expression of CYP26B1 mRNA CTD PMID:26745496 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 increases methylation
decreases expression
EXP manganese chloride results in increased methylation of CYP4F4 gene
manganese chloride results in decreased expression of CYP4F4 mRNA
CTD PMID:28801915 NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506
JBrowse link
G Cyria CYFIP related Rac1 interactor A increases methylation
increases expression
EXP manganese chloride results in increased methylation of CYRIA gene
manganese chloride results in increased expression of CYRIA mRNA
CTD PMID:28801915 NCBI chr 6:35,045,208...35,150,669
Ensembl chr 6:35,045,208...35,150,668
JBrowse link
G Dach2 dachshund family transcription factor 2 increases expression ISO manganese chloride results in increased expression of DACH2 mRNA CTD PMID:17175027 NCBI chr  X:78,718,963...79,018,023
Ensembl chr  X:78,451,593...79,017,592
JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 decreases expression EXP manganese chloride results in decreased expression of DACT1 mRNA CTD PMID:28801915 NCBI chr 6:89,790,676...89,818,254
Ensembl chr 6:89,790,644...89,817,906
JBrowse link
G Dbh dopamine beta-hydroxylase increases methylation ISO manganese chloride results in increased methylation of DBH gene CTD PMID:27913844 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor increases expression EXP manganese chloride results in increased expression of DBP mRNA CTD PMID:28511934 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
JBrowse link
G Dcp1b decapping mRNA 1B increases expression EXP manganese chloride results in increased expression of DCP1B mRNA CTD PMID:28801915 NCBI chr 4:152,358,267...152,395,747
Ensembl chr 4:152,358,241...152,397,145
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO
EXP
Deferoxamine promotes the reaction [manganese chloride results in increased expression of DDIT3 protein]
[manganese chloride results in increased abundance of Manganese] which results in increased expression of DDIT3 mRNA; SNCA protein promotes the reaction [manganese chloride results in increased expression of DDIT3 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of DDIT3 protein]
manganese chloride results in increased expression of DDIT3 mRNA; manganese chloride results in increased expression of DDIT3 protein
CTD PMID:23764342 PMID:23934647 PMID:23948121 PMID:25732873 PMID:32574669 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddx60 DEXD/H-box helicase 60 increases expression EXP manganese chloride results in increased expression of DDX60 mRNA CTD PMID:28801915 NCBI chr16:28,077,000...28,197,903
Ensembl chr16:28,076,999...28,179,526
JBrowse link
G Defb29 defensin beta 29 increases methylation
increases expression
EXP manganese chloride results in increased methylation of DEFB29 gene
manganese chloride results in increased expression of DEFB29 mRNA
CTD PMID:28801915 NCBI chr 3:141,004,098...141,009,379
Ensembl chr 3:141,004,098...141,005,557
JBrowse link
G Depp1 DEPP1, autophagy regulator increases expression EXP manganese chloride results in increased expression of DEPP1 mRNA CTD PMID:28801915 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 decreases expression EXP manganese chloride results in decreased expression of DHRS3 mRNA CTD PMID:28801915 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
JBrowse link
G Dld dihydrolipoamide dehydrogenase decreases expression EXP manganese chloride results in decreased expression of DLD protein CTD PMID:25981801 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 increases methylation
decreases expression
ISO manganese chloride results in increased methylation of DLK1 gene
manganese chloride results in decreased expression of DLK1 mRNA
CTD PMID:27913844 NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522
JBrowse link
G Dll4 delta like canonical Notch ligand 4 increases expression ISO manganese chloride results in increased expression of DLL4 mRNA CTD PMID:17467022 NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931
JBrowse link
G Dmkn dermokine increases expression EXP manganese chloride results in increased expression of DMKN mRNA CTD PMID:28801915 NCBI chr 1:86,013,237...86,031,243
Ensembl chr 1:86,014,188...86,030,006
JBrowse link
G Dnah14 dynein axonemal heavy chain 14 decreases expression ISO manganese chloride results in decreased expression of DNAH14 mRNA CTD PMID:17175027 NCBI chr13:93,322,653...93,540,706
Ensembl chr13:93,322,711...93,538,646
JBrowse link
G Dnai2 dynein, axonemal, intermediate chain 2 decreases expression EXP manganese chloride results in decreased expression of DNAI2 mRNA CTD PMID:28801915 NCBI chr10:99,759,966...99,793,379
Ensembl chr10:99,759,966...99,793,378
JBrowse link
G Dnajc12 DnaJ heat shock protein family (Hsp40) member C12 increases expression EXP manganese chloride results in increased expression of DNAJC12 mRNA CTD PMID:28801915 NCBI chr20:25,246,744...25,267,508
Ensembl chr20:25,223,144...25,267,521
JBrowse link
G Dnajc16 DnaJ heat shock protein family (Hsp40) member C16 increases expression EXP manganese chloride results in increased expression of DNAJC16 mRNA CTD PMID:28801915 NCBI chr 5:154,073,372...154,106,246
Ensembl chr 5:154,075,261...154,106,136
JBrowse link
G Dnm1l dynamin 1-like increases expression
multiple interactions
ISO manganese chloride results in increased expression of DNM1L mRNA; manganese chloride results in increased expression of DNM1L protein
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride promotes the reaction [PPARGC1A protein binds to DNM1L promoter]]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride results in increased expression of DNM1L mRNA]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride results in increased expression of DNM1L protein]]; manganese chloride promotes the reaction [PPARGC1A protein binds to DNM1L promoter]; Resveratrol inhibits the reaction [manganese chloride promotes the reaction [PPARGC1A protein binds to DNM1L promoter]]; Resveratrol inhibits the reaction [manganese chloride results in increased expression of DNM1L mRNA]; Resveratrol inhibits the reaction [manganese chloride results in increased expression of DNM1L protein]
CTD PMID:34738708 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 decreases expression ISO manganese chloride results in decreased expression of DNPH1 mRNA CTD PMID:17175027 NCBI chr 9:14,481,296...14,484,034
Ensembl chr 9:14,481,066...14,484,022
JBrowse link
G Doc2a double C2 domain alpha increases expression EXP manganese chloride results in increased expression of DOC2A mRNA CTD PMID:28801915 NCBI chr 1:181,457,415...181,462,528
Ensembl chr 1:181,458,390...181,462,030
JBrowse link
G Dpep1 dipeptidase 1 decreases expression EXP manganese chloride results in decreased expression of DPEP1 mRNA CTD PMID:28801915 NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257
JBrowse link
G Dpep2 dipeptidase 2 increases expression EXP manganese chloride results in increased expression of DPEP2 mRNA CTD PMID:28801915 NCBI chr19:33,883,557...33,896,487
Ensembl chr19:33,885,478...33,891,954
JBrowse link
G Dph1 diphthamide biosynthesis 1 increases expression EXP manganese chloride results in increased expression of DPH1 mRNA CTD PMID:28801915 NCBI chr10:60,028,081...60,039,764
Ensembl chr10:60,026,048...60,039,850
JBrowse link
G Dpp4 dipeptidylpeptidase 4 increases expression ISO manganese chloride results in increased expression of DPP4 mRNA CTD PMID:17175027 NCBI chr 3:46,962,243...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 decreases expression
increases expression
ISO
EXP
manganese chloride results in decreased expression of DPYSL3 mRNA
manganese chloride results in increased expression of DPYSL3 mRNA
CTD PMID:22407947 PMID:25698507 PMID:28801915 NCBI chr18:35,374,429...35,480,462
Ensembl chr18:35,377,181...35,480,157
JBrowse link
G Dr1 down-regulator of transcription 1 decreases expression ISO manganese chloride results in decreased expression of DR1 mRNA CTD PMID:17175027 NCBI chr14:1,458,223...1,469,578
Ensembl chr14:1,458,223...1,469,638
JBrowse link
G Drd1 dopamine receptor D1 decreases expression
multiple interactions
increases expression
ISO
EXP
manganese chloride results in decreased expression of DRD1 protein
Melatonin inhibits the reaction [manganese chloride results in decreased expression of DRD1 protein]
manganese chloride results in increased expression of DRD1
[manganese chloride co-treated with Iron deficiency] results in decreased expression of DRD1 protein
CTD PMID:22479410 PMID:23458069 PMID:23604964 PMID:24969583 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
increases expression
decreases expression
EXP
ISO
[manganese chloride co-treated with Iron deficiency] results in increased expression of DRD2 protein; manganese chloride inhibits the reaction [DRD2 protein binds to Spiperone]
manganese chloride results in increased expression of DRD2; manganese chloride results in increased expression of DRD2 protein; manganese chloride results in increased expression of DRD2 protein alternative form
manganese chloride results in decreased expression of DRD2 protein
Melatonin promotes the reaction [manganese chloride results in decreased expression of DRD2 protein]
CTD PMID:21484877 PMID:22479410 PMID:23458069 PMID:24969583 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Dscaml1 DS cell adhesion molecule-like 1 increases expression EXP manganese chloride results in increased expression of DSCAML1 mRNA CTD PMID:26745496 NCBI chr 8:45,740,298...46,057,322
Ensembl chr 8:45,740,298...46,057,320
JBrowse link
G Dspp dentin sialophosphoprotein increases expression ISO manganese chloride results in increased expression of DSPP mRNA CTD PMID:17175027 NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672
JBrowse link
G Dtx1 deltex E3 ubiquitin ligase 1 increases expression EXP manganese chloride results in increased expression of DTX1 mRNA CTD PMID:28801915 NCBI chr12:35,849,647...35,880,835
Ensembl chr12:35,849,617...35,880,838
JBrowse link
G Dusp13 dual specificity phosphatase 13 increases expression EXP manganese chloride results in increased expression of DUSP13 mRNA CTD PMID:28801915 NCBI chr15:2,559,720...2,575,105
Ensembl chr15:2,533,547...2,575,539
JBrowse link
G Dusp2 dual specificity phosphatase 2 increases expression EXP manganese chloride results in increased expression of DUSP2 mRNA CTD PMID:28801915 NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499
JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression EXP manganese chloride results in increased expression of DUSP4 mRNA CTD PMID:28801915 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression
increases methylation
EXP manganese chloride results in increased expression of DUSP5 mRNA
manganese chloride results in increased methylation of DUSP5 gene
CTD PMID:28801915 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
JBrowse link
G Dusp6 dual specificity phosphatase 6 increases methylation
increases expression
EXP manganese chloride results in increased methylation of DUSP6 gene
manganese chloride results in increased expression of DUSP6 mRNA
CTD PMID:28801915 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Dynlt4 dynein light chain Tctex-type 4 increases expression EXP manganese chloride results in increased expression of DYNLT4 mRNA CTD PMID:28801915 NCBI chr 5:130,605,417...130,607,224
Ensembl chr 5:130,605,399...130,607,666
JBrowse link
G Eaf2 ELL associated factor 2 increases expression
increases methylation
EXP manganese chloride results in increased expression of EAF2 mRNA
manganese chloride results in increased methylation of EAF2 gene
CTD PMID:28801915 NCBI chr11:63,960,200...64,004,610
Ensembl chr11:63,960,200...64,004,610
JBrowse link
G Ebi3 Epstein-Barr virus induced 3 increases expression EXP manganese chloride results in increased expression of EBI3 mRNA CTD PMID:28801915 NCBI chr 9:774,252...787,544
Ensembl chr 9:783,617...787,544
JBrowse link
G Ecrg4 ECRG4 augurin precursor decreases expression EXP manganese chloride results in decreased expression of ECRG4 mRNA CTD PMID:28801915 NCBI chr 9:45,992,954...46,012,605
Ensembl chr 9:45,992,954...46,012,595
JBrowse link
G Edn1 endothelin 1 decreases expression EXP manganese chloride results in decreased expression of EDN1 mRNA CTD PMID:28801915 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Egf epidermal growth factor multiple interactions ISO [manganese chloride co-treated with EGF protein] results in increased activity of EGFR protein CTD PMID:2354210 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfl7 EGF-like-domain, multiple 7 increases expression ISO manganese chloride results in increased expression of EGFL7 mRNA CTD PMID:17467022 NCBI chr 3:9,404,622...9,416,879
Ensembl chr 3:9,407,520...9,416,879
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases activity
increases expression
ISO
EXP
[manganese chloride co-treated with EGF protein] results in increased activity of EGFR protein
manganese chloride results in increased activity of EGFR protein
manganese chloride results in increased expression of EGFR mRNA
CTD PMID:2354210 PMID:28801915 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 increases expression EXP manganese chloride results in increased expression of EGLN3 mRNA CTD PMID:28801915 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Egr1 early growth response 1 increases expression EXP
ISO
manganese chloride results in increased expression of EGR1 mRNA CTD PMID:28801915 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr2 early growth response 2 increases expression ISO
EXP
manganese chloride results in increased expression of EGR2 mRNA CTD PMID:28801915 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Egr3 early growth response 3 increases expression EXP manganese chloride results in increased expression of EGR3 mRNA CTD PMID:28801915 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627
JBrowse link
G Eif1ad eukaryotic translation initiation factor 1A domain containing increases expression EXP manganese chloride results in increased expression of EIF1AD mRNA CTD PMID:28801915 NCBI chr 1:202,674,362...202,679,662
Ensembl chr 1:202,674,185...202,679,658
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A multiple interactions EXP manganese chloride results in increased expression of and results in increased phosphorylation of EIF2A protein; SNCA protein promotes the reaction [manganese chloride results in increased expression of and results in increased phosphorylation of EIF2A protein] CTD PMID:23934647 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in increased cleavage of EIF2AK2 protein; GW 506033X inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of EIF2AK2 protein]; pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of EIF2AK2 protein] CTD PMID:32574669 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation
increases expression
EXP [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of EIF2AK3 protein; manganese chloride promotes the reaction [EIF2AK3 protein results in increased expression of ATF4 mRNA]; manganese chloride promotes the reaction [EIF2AK3 protein results in increased phosphorylation of EIF2S1 protein]; manganese chloride results in increased expression of and results in increased phosphorylation of EIF2AK3 protein; SNCA protein promotes the reaction [manganese chloride results in increased expression of and results in increased phosphorylation of EIF2AK3 protein]
manganese chloride results in increased phosphorylation of EIF2AK3 protein
manganese chloride results in increased expression of EIF2AK3 protein
CTD PMID:23934647 PMID:23948121 PMID:25732873 PMID:32574669 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation
multiple interactions
ISO
EXP
manganese chloride results in increased phosphorylation of EIF2S1 protein
[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of EIF2S1 protein; manganese chloride promotes the reaction [EIF2AK3 protein results in increased phosphorylation of EIF2S1 protein]
CTD PMID:23764342 PMID:23948121 PMID:32574669 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
decreases phosphorylation
ISO corynoxine B promotes the reaction [manganese chloride results in decreased phosphorylation of EIF4EBP1 protein] CTD PMID:30578841 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Elf1 E74 like ETS transcription factor 1 decreases expression ISO manganese chloride results in decreased expression of ELF1 mRNA CTD PMID:17175027 NCBI chr15:54,890,644...54,986,721
Ensembl chr15:54,865,616...54,986,699
JBrowse link
G Elk3 ETS transcription factor ELK3 increases expression ISO manganese chloride results in increased expression of ELK3 mRNA CTD PMID:17467022 NCBI chr 7:27,768,582...27,831,088
Ensembl chr 7:27,768,599...27,804,084
JBrowse link
G Elmod3 ELMO domain containing 3 increases expression EXP manganese chloride results in increased expression of ELMOD3 mRNA CTD PMID:28801915 NCBI chr 4:104,614,665...104,653,122
Ensembl chr 4:104,614,676...104,653,053
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 decreases expression EXP manganese chloride results in decreased expression of ELOVL6 mRNA CTD PMID:28801915 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
JBrowse link
G Eml2 EMAP like 2 increases expression ISO manganese chloride results in increased expression of EML2 mRNA CTD PMID:17175027 NCBI chr 1:78,827,595...78,859,343
Ensembl chr 1:78,828,080...78,859,341
JBrowse link
G Enc1 ectodermal-neural cortex 1 decreases expression EXP manganese chloride results in decreased expression of ENC1 mRNA CTD PMID:28801915 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
JBrowse link
G Eng endoglin increases expression ISO manganese chloride results in increased expression of ENG mRNA CTD PMID:17467022 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Eno2 enolase 2 increases expression
decreases expression
multiple interactions
EXP
ISO
manganese chloride results in increased expression of ENO2 mRNA
manganese chloride results in decreased expression of ENO2 protein
Melatonin inhibits the reaction [manganese chloride results in decreased expression of ENO2 protein]
CTD PMID:22281203 PMID:24969583 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Eomes eomesodermin decreases expression ISO manganese chloride results in decreased expression of EOMES mRNA; manganese chloride results in decreased expression of EOMES protein CTD PMID:25698507 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316
JBrowse link
G Epas1 endothelial PAS domain protein 1 increases expression ISO manganese chloride results in increased expression of EPAS1 mRNA CTD PMID:17467022 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Epdr1 ependymin related 1 increases expression EXP manganese chloride results in increased expression of EPDR1 mRNA CTD PMID:28801915 NCBI chr17:45,333,677...45,358,597
Ensembl chr17:45,333,956...45,358,594
JBrowse link
G Epha2 Eph receptor A2 increases expression EXP manganese chloride results in increased expression of EPHA2 mRNA CTD PMID:28801915 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117
JBrowse link
G Epha4 Eph receptor A4 increases methylation
decreases expression
EXP manganese chloride results in increased methylation of EPHA4 gene
manganese chloride results in decreased expression of EPHA4 mRNA
CTD PMID:28801915 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 increases expression ISO manganese chloride results in increased expression of ERAP1 mRNA CTD PMID:17467022 NCBI chr 2:3,931,817...3,970,735
Ensembl chr 2:3,931,904...3,972,447
JBrowse link
G Ercc6l ERCC excision repair 6 like, spindle assembly checkpoint helicase decreases expression ISO manganese chloride results in decreased expression of ERCC6L mRNA CTD PMID:17175027 NCBI chr  X:67,245,414...67,261,222
Ensembl chr  X:67,245,414...67,280,756
JBrowse link
G Ereg epiregulin increases expression ISO manganese chloride results in increased expression of EREG mRNA CTD PMID:17175027 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
JBrowse link
G Erich1 glutamate-rich 1 increases expression ISO manganese chloride results in increased expression of ERICH1 mRNA CTD PMID:17175027 NCBI chr16:75,501,322...75,569,129
Ensembl chr16:75,501,384...75,569,128
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases phosphorylation
EXP SNCA protein promotes the reaction [manganese chloride results in increased phosphorylation of ERN1 protein] CTD PMID:23934647 PMID:25732873 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 increases expression EXP manganese chloride results in increased expression of ERRFI1 mRNA CTD PMID:28801915 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases expression
ISO Estradiol inhibits the reaction [manganese chloride results in decreased expression of ESR1 protein]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of ESR1 protein] CTD PMID:29183790 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Etv3 ETS variant transcription factor 3 increases expression EXP manganese chloride results in increased expression of ETV3 mRNA CTD PMID:28801915 NCBI chr 2:172,965,461...172,980,320
Ensembl chr 2:172,965,588...172,980,314
JBrowse link
G Etv4 ETS variant transcription factor 4 increases expression EXP manganese chloride results in increased expression of ETV4 mRNA CTD PMID:28801915 NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974
JBrowse link
G Etv5 ETS variant transcription factor 5 increases expression EXP manganese chloride results in increased expression of ETV5 mRNA CTD PMID:28801915 NCBI chr11:78,608,618...78,666,221
Ensembl chr11:78,608,710...78,666,215
JBrowse link
G Eva1c eva-1 homolog C increases expression EXP manganese chloride results in increased expression of EVA1C mRNA CTD PMID:28801915 NCBI chr11:30,089,510...30,163,596
Ensembl chr11:30,089,365...30,163,596
JBrowse link
G Exoc6 exocyst complex component 6 decreases expression ISO manganese chloride results in decreased expression of EXOC6 mRNA CTD PMID:17175027 NCBI chr 1:235,314,612...235,457,824
Ensembl chr 1:235,300,369...235,457,015
JBrowse link
G Eya4 EYA transcriptional coactivator and phosphatase 4 decreases expression ISO manganese chloride results in decreased expression of EYA4 mRNA CTD PMID:17175027 NCBI chr 1:22,172,275...22,415,978
Ensembl chr 1:22,172,275...22,415,976
JBrowse link
G F2rl1 F2R like trypsin receptor 1 increases expression EXP manganese chloride results in increased expression of F2RL1 mRNA CTD PMID:28801915 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G Fa2h fatty acid 2-hydroxylase increases expression
decreases expression
EXP manganese chloride results in increased expression of FA2H mRNA
manganese chloride results in decreased expression of FA2H mRNA
CTD PMID:26745496 PMID:28801915 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153
JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression EXP manganese chloride results in decreased expression of FADS2 mRNA CTD PMID:28801915 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
JBrowse link
G Fam107a family with sequence similarity 107, member A decreases expression EXP manganese chloride results in decreased expression of FAM107A mRNA CTD PMID:26745496 NCBI chr15:16,608,362...16,630,398
Ensembl chr15:16,607,205...16,630,396
JBrowse link
G Fam171b family with sequence similarity 171, member B increases expression EXP manganese chloride results in increased expression of FAM171B mRNA CTD PMID:28801915 NCBI chr 3:68,930,755...68,986,113
Ensembl chr 3:68,930,822...68,986,127
JBrowse link
G Fam180a family with sequence similarity 180, member A decreases expression EXP manganese chloride results in decreased expression of FAM180A mRNA CTD PMID:26745496 NCBI chr 4:63,992,867...64,008,047
Ensembl chr 4:63,992,867...64,008,047
JBrowse link
G Fam210a family with sequence similarity 210, member A increases expression EXP manganese chloride results in increased expression of FAM210A mRNA CTD PMID:28801915 NCBI chr18:61,846,447...61,886,123
Ensembl chr18:61,852,907...61,886,171
JBrowse link
G Fam210b family with sequence similarity 210, member B increases expression EXP manganese chloride results in increased expression of FAM210B mRNA CTD PMID:28801915 NCBI chr 3:161,118,228...161,128,400
Ensembl chr 3:161,118,239...161,128,397
JBrowse link
G Fam219a family with sequence similarity 219, member A increases expression EXP manganese chloride results in increased expression of FAM219A mRNA CTD PMID:28801915 NCBI chr 5:56,679,272...56,729,959
Ensembl chr 5:56,680,613...56,729,924
JBrowse link
G Fam227a family with sequence similarity 227, member A increases expression EXP manganese chloride results in increased expression of FAM227A mRNA CTD PMID:28801915 NCBI chr 7:111,174,362...111,216,513
Ensembl chr 7:111,174,362...111,216,483
JBrowse link
G Fam229b family with sequence similarity 229, member B increases expression EXP manganese chloride results in increased expression of FAM229B mRNA CTD PMID:28801915 NCBI chr20:42,538,853...42,552,355
Ensembl chr20:42,538,868...42,552,248
JBrowse link
G Fancf FA complementation group F decreases expression ISO manganese chloride results in decreased expression of FANCF mRNA CTD PMID:17175027 NCBI chr 1:101,449,120...101,452,361
Ensembl chr 1:101,450,389...101,451,923
JBrowse link
G Fas Fas cell surface death receptor increases expression EXP manganese chloride results in increased expression of FAS mRNA CTD PMID:28801915 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand increases expression
multiple interactions
EXP manganese chloride results in increased expression of FASLG protein
bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of FASLG protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased expression of FASLG protein]; pepstatin inhibits the reaction [manganese chloride results in increased expression of FASLG protein]
CTD PMID:21704098 PMID:28378122 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fasn fatty acid synthase decreases expression EXP manganese chloride results in decreased expression of FASN mRNA CTD PMID:28801915 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fat2 FAT atypical cadherin 2 increases methylation EXP manganese chloride results in increased methylation of FAT2 gene CTD PMID:28801915 NCBI chr10:39,364,072...39,456,324
Ensembl chr10:39,364,073...39,456,216
JBrowse link
G Fat4 FAT atypical cadherin 4 decreases expression EXP manganese chloride results in decreased expression of FAT4 mRNA CTD PMID:28801915 NCBI chr 2:121,928,188...122,056,711
Ensembl chr 2:121,927,942...122,056,707
JBrowse link
G Fbln2 fibulin 2 increases expression EXP manganese chloride results in increased expression of FBLN2 mRNA CTD PMID:28801915 NCBI chr 4:123,704,289...123,763,857
Ensembl chr 4:123,704,373...123,763,948
JBrowse link
G Fbn1 fibrillin 1 increases expression EXP manganese chloride results in increased expression of FBN1 mRNA CTD PMID:28801915 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Fbp2 fructose-bisphosphatase 2 increases expression EXP manganese chloride results in increased expression of FBP2 mRNA CTD PMID:28801915 NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698
JBrowse link
G Fbxl2 F-box and leucine-rich repeat protein 2 increases expression EXP manganese chloride results in increased expression of FBXL2 mRNA CTD PMID:28801915 NCBI chr 8:113,916,660...113,965,137
Ensembl chr 8:113,913,373...113,965,066
JBrowse link
G Fbxl4 F-box and leucine-rich repeat protein 4 increases expression EXP manganese chloride results in increased expression of FBXL4 mRNA CTD PMID:28801915 NCBI chr 5:35,955,801...36,029,446
Ensembl chr 5:35,955,812...36,029,443
JBrowse link
G Fcgr1a Fc gamma receptor 1A decreases expression EXP manganese chloride results in decreased expression of FCGR1A mRNA CTD PMID:26745496 NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994
JBrowse link
G Fcgr3a Fc gamma receptor 3A increases expression EXP manganese chloride results in increased expression of FCGR3A mRNA CTD PMID:28801915 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921
JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression EXP manganese chloride results in decreased expression of FDPS mRNA CTD PMID:28801915 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Fdps-ps4 farnesyl diphosphate synthase, pseudogene 4 decreases expression EXP manganese chloride results in decreased expression of FDPS-PS4 mRNA CTD PMID:28801915 NCBI chr 8:18,816,786...18,818,020 JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 increases expression EXP manganese chloride results in increased expression of FEZ1 mRNA CTD PMID:28801915 NCBI chr 8:36,544,462...36,589,684
Ensembl chr 8:36,544,535...36,589,683
JBrowse link
G Fez2 fasciculation and elongation protein zeta 2 increases expression EXP manganese chloride results in increased expression of FEZ2 mRNA CTD PMID:28801915 NCBI chr 6:16,654,572...16,694,628
Ensembl chr 6:16,654,614...16,694,626
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression
increases methylation
ISO
EXP
manganese chloride results in decreased expression of FGF2 mRNA
manganese chloride results in increased methylation of FGF2 gene
CTD PMID:28801915 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgf20 fibroblast growth factor 20 increases expression ISO manganese chloride results in increased expression of FGF20 mRNA CTD PMID:28986288 NCBI chr16:52,030,853...52,037,612
Ensembl chr16:52,010,194...52,038,204
JBrowse link
G Fgfbp1 fibroblast growth factor binding protein 1 decreases expression EXP manganese chloride results in decreased expression of FGFBP1 mRNA CTD PMID:26745496 NCBI chr14:67,103,686...67,107,492
Ensembl chr14:67,104,545...67,107,496
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 decreases expression EXP manganese chloride results in decreased expression of FGFR2 mRNA CTD PMID:28801915 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Fhip2b FHF complex subunit HOOK interacting protein 2B increases expression EXP manganese chloride results in increased expression of FHIP2B mRNA CTD PMID:28801915 NCBI chr15:45,656,641...45,674,603
Ensembl chr15:45,656,647...45,674,105
JBrowse link
G Fhl1 four and a half LIM domains 1 decreases expression ISO manganese chloride results in decreased expression of FHL1 mRNA CTD PMID:17175027 NCBI chr  X:134,555,399...134,614,930
Ensembl chr  X:134,555,479...134,614,928
JBrowse link
G Fis1 fission, mitochondrial 1 increases expression ISO manganese chloride results in increased expression of FIS1 protein CTD PMID:34738708 NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Flcn folliculin increases expression ISO manganese chloride results in increased expression of FLCN mRNA CTD PMID:17175027 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Flrt2 fibronectin leucine rich transmembrane protein 2 increases expression EXP manganese chloride results in increased expression of FLRT2 mRNA CTD PMID:28801915 NCBI chr 6:114,777,547...114,872,688
Ensembl chr 6:114,777,599...114,872,785
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 increases expression ISO manganese chloride results in increased expression of FLT1 mRNA CTD PMID:17467022 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Flvcr2 FLVCR heme transporter 2 decreases expression EXP manganese chloride results in decreased expression of FLVCR2 mRNA CTD PMID:28801915 NCBI chr 6:105,408,355...105,472,355
Ensembl chr 6:105,408,339...105,472,353
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 increases expression EXP manganese chloride results in increased expression of FMO2 mRNA CTD PMID:28801915 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 decreases methylation
increases expression
EXP manganese chloride results in decreased methylation of FMO5 gene
manganese chloride results in increased expression of FMO5 mRNA
CTD PMID:28801915 NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
JBrowse link
G Fn1 fibronectin 1 multiple interactions
increases expression
EXP [Buthionine Sulfoximine results in decreased abundance of Glutathione] promotes the reaction [manganese chloride results in increased expression of and results in increased secretion of FN1 protein]; [S-ethyl glutathione results in increased abundance of Glutathione] inhibits the reaction [manganese chloride results in increased expression of and results in increased secretion of FN1 protein]; [S-ethyl glutathione results in increased abundance of Glutathione] inhibits the reaction [manganese chloride results in increased expression of FN1 mRNA]; manganese chloride results in increased expression of and results in increased secretion of FN1 protein; Melatonin inhibits the reaction [manganese chloride results in increased expression of and results in increased secretion of FN1 protein]; Melatonin inhibits the reaction [manganese chloride results in increased expression of FN1 mRNA]; phenyl-N-tert-butylnitrone inhibits the reaction [manganese chloride results in increased expression of FN1 mRNA] CTD PMID:19524604 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
decreases expression
EXP
ISO
manganese chloride results in increased expression of FOS protein
manganese chloride results in decreased expression of FOS protein
CTD PMID:9751194 PMID:25698507 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression EXP manganese chloride results in increased expression of FOSL1 mRNA CTD PMID:28801915 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Foxn4 forkhead box N4 increases expression EXP manganese chloride results in increased expression of FOXN4 mRNA CTD PMID:26745496 NCBI chr12:42,336,706...42,359,932
Ensembl chr12:42,340,323...42,359,921
JBrowse link
G Foxp2 forkhead box P2 increases expression ISO manganese chloride results in increased expression of FOXP2 mRNA CTD PMID:17175027 NCBI chr 4:43,133,827...43,712,442
Ensembl chr 4:43,133,912...43,711,683
JBrowse link
G Frem3 FRAS1 related extracellular matrix 3 increases expression EXP manganese chloride results in increased expression of FREM3 mRNA CTD PMID:28801915 NCBI chr19:27,308,469...27,366,771
Ensembl chr19:27,308,469...27,366,771
JBrowse link
G Frmd4a FERM domain containing 4A increases expression EXP manganese chloride results in increased expression of FRMD4A mRNA CTD PMID:28801915 NCBI chr17:73,667,787...74,258,487
Ensembl chr17:73,667,789...74,258,687
JBrowse link
G Fscn2 fascin actin-bundling protein 2, retinal decreases expression EXP manganese chloride results in decreased expression of FSCN2 mRNA CTD PMID:28801915 NCBI chr10:105,634,783...105,641,322
Ensembl chr10:105,634,783...105,641,322
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions
decreases expression
EXP Quercetin inhibits the reaction [manganese chloride results in decreased expression of FSHB protein] CTD PMID:28040552 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Fstl3 follistatin like 3 increases expression EXP manganese chloride results in increased expression of FSTL3 mRNA CTD PMID:28801915 NCBI chr 7:9,924,670...9,929,195
Ensembl chr 7:9,923,576...9,939,639
JBrowse link
G Fth1 ferritin heavy chain 1 decreases expression EXP manganese chloride results in decreased expression of FTH1 mRNA; manganese chloride results in decreased expression of FTH1 protein CTD PMID:15893546 PMID:15922012 PMID:16545456 PMID:16568477 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Ftl1 ferritin light chain 1 decreases expression EXP manganese chloride results in decreased expression of FTL mRNA CTD PMID:15893546 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
JBrowse link
G Fut1 fucosyltransferase 1 increases expression EXP manganese chloride results in increased expression of FUT1 mRNA CTD PMID:28801915 NCBI chr 1:96,086,934...96,090,352
Ensembl chr 1:96,086,635...96,090,616
JBrowse link
G Fut2 fucosyltransferase 2 decreases expression
increases methylation
EXP manganese chloride results in decreased expression of FUT2 mRNA
manganese chloride results in increased methylation of FUT2 gene
CTD PMID:28801915 NCBI chr 1:96,119,549...96,139,567
Ensembl chr 1:96,119,371...96,140,360
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 increases expression ISO manganese chloride results in increased expression of FXYD2 mRNA CTD PMID:17175027 NCBI chr 8:45,712,887...45,720,032
Ensembl chr 8:45,712,903...45,720,203
JBrowse link
G G0s2 G0/G1switch 2 increases expression EXP manganese chloride results in increased expression of G0S2 mRNA CTD PMID:28801915 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 multiple interactions
decreases expression
EXP
ISO
[Iron deficiency co-treated with manganese chloride] results in decreased expression of GABBR2 mRNA; [Iron deficiency co-treated with manganese chloride] results in decreased expression of GABBR2 protein
manganese chloride results in decreased expression of GABBR2 mRNA
[manganese chloride results in increased abundance of Manganese] which results in increased expression of GABBR2 protein
CTD PMID:18771689 PMID:32659473 NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions
decreases expression
increases expression
EXP
ISO
[Iron deficiency co-treated with manganese chloride] results in increased expression of GABRA1 protein
manganese chloride results in decreased expression of GABRA1 mRNA
manganese chloride results in increased expression of GABRA1 protein
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of GABRA1 protein
CTD PMID:18771689 PMID:32659473 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 decreases expression EXP manganese chloride results in decreased expression of GABRB3 mRNA CTD PMID:28801915 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 increases expression ISO manganese chloride results in increased expression of GABRG2 mRNA CTD PMID:17175027 NCBI chr10:26,376,805...26,463,680
Ensembl chr10:26,374,694...26,464,346
JBrowse link
G Gad1 glutamate decarboxylase 1 decreases expression EXP manganese chloride results in decreased expression of GAD1 mRNA CTD PMID:12106697 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression EXP manganese chloride results in decreased expression of GADD45A mRNA CTD PMID:28801915 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gal galanin and GMAP prepropeptide increases expression ISO manganese chloride results in increased expression of GAL mRNA CTD PMID:17175027 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
JBrowse link
G Gale UDP-galactose-4-epimerase decreases expression EXP manganese chloride results in decreased expression of GALE mRNA CTD PMID:28801915 NCBI chr 5:148,193,886...148,198,392
Ensembl chr 5:148,194,791...148,198,388
JBrowse link
G Garin1b golgi associated RAB2 interactor 1B increases expression EXP manganese chloride results in increased expression of GARIN1B mRNA CTD PMID:28801915 NCBI chr 4:57,915,184...57,938,593
Ensembl chr 4:57,920,790...57,938,591
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 increases methylation
decreases expression
ISO manganese chloride results in increased methylation of GBE1 gene
manganese chloride results in decreased expression of GBE1 mRNA
CTD PMID:27913844 NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210
JBrowse link
G Gbp5 guanylate binding protein 5 increases methylation
increases expression
EXP manganese chloride results in increased methylation of GBP5 gene
manganese chloride results in increased expression of GBP5 mRNA
CTD PMID:28801915 NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061
JBrowse link
G Gcdh glutaryl-CoA dehydrogenase decreases expression EXP manganese chloride results in decreased expression of GCDH mRNA CTD PMID:22281203 NCBI chr19:23,263,215...23,269,689
Ensembl chr19:23,263,264...23,269,681
JBrowse link
G Gcfc2 GC-rich sequence DNA-binding factor 2 decreases expression ISO manganese chloride results in decreased expression of GCFC2 mRNA CTD PMID:17175027 NCBI chr 4:114,481,613...114,519,268
Ensembl chr 4:114,481,607...114,519,962
JBrowse link
G Gcgr glucagon receptor decreases expression
increases methylation
EXP manganese chloride results in decreased expression of GCGR mRNA
manganese chloride results in increased methylation of GCGR gene
CTD PMID:28801915 NCBI chr10:105,808,474...105,816,641
Ensembl chr10:105,808,473...105,816,640
JBrowse link
G Gch1 GTP cyclohydrolase 1 decreases expression EXP manganese chloride results in decreased expression of GCH1 mRNA CTD PMID:28801915 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
G Gdap2 ganglioside-induced differentiation-associated-protein 2 increases expression ISO manganese chloride results in increased expression of GDAP2 mRNA CTD PMID:17175027 NCBI chr 2:187,528,514...187,585,270
Ensembl chr 2:187,528,513...187,585,270
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO manganese chloride results in increased expression of GDF15 mRNA CTD PMID:17175027 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gdnf glial cell derived neurotrophic factor increases methylation ISO manganese chloride results in increased methylation of GDNF gene CTD PMID:27913844 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression
increases expression
multiple interactions
EXP
ISO
manganese chloride results in decreased expression of GFAP protein
manganese chloride results in increased expression of GFAP protein
Melatonin inhibits the reaction [manganese chloride results in increased expression of GFAP protein]
CTD PMID:12009774 PMID:12106697 PMID:24060432 PMID:24969583 PMID:25288107 More... NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP manganese chloride results in decreased expression of GJA1 mRNA CTD PMID:28801915 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gja5 gap junction protein, alpha 5 decreases expression EXP manganese chloride results in decreased expression of GJA5 mRNA CTD PMID:26745496 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952
JBrowse link
G Gja8 gap junction protein, alpha 8 increases expression EXP manganese chloride results in increased expression of GJA8 mRNA CTD PMID:28801915 NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456
JBrowse link
G Gjb5 gap junction protein, beta 5 increases expression EXP manganese chloride results in increased expression of GJB5 mRNA CTD PMID:28801915 NCBI chr 5:139,680,670...139,683,588
Ensembl chr 5:139,680,671...139,683,583
JBrowse link
G Gkn3 gastrokine 3 decreases expression EXP manganese chloride results in decreased expression of GKN3 mRNA CTD PMID:28801915 NCBI chr 4:119,828,859...119,833,924
Ensembl chr 4:119,829,005...119,834,842
JBrowse link
G Gldn gliomedin decreases expression EXP manganese chloride results in decreased expression of GLDN mRNA CTD PMID:26745496 NCBI chr 8:54,679,015...54,723,198
Ensembl chr 8:54,679,119...54,723,196
JBrowse link
G Glis1 GLIS family zinc finger 1 decreases expression EXP manganese chloride results in decreased expression of GLIS1 mRNA CTD PMID:28801915 NCBI chr 5:122,222,155...122,412,141
Ensembl chr 5:122,222,128...122,412,141
JBrowse link
G Glis2 GLIS family zinc finger 2 increases expression EXP manganese chloride results in increased expression of GLIS2 mRNA CTD PMID:28801915 NCBI chr10:10,951,157...10,978,524
Ensembl chr10:10,951,371...10,971,578
JBrowse link
G Glt8d2 glycosyltransferase 8 domain containing 2 increases expression EXP manganese chloride results in increased expression of GLT8D2 mRNA CTD PMID:28801915 NCBI chr 7:21,029,534...21,081,081
Ensembl chr 7:21,029,525...21,081,080
JBrowse link
G Glul glutamate-ammonia ligase decreases expression
multiple interactions
EXP manganese chloride results in decreased expression of GLUL mRNA; manganese chloride results in decreased expression of GLUL protein
Riluzole inhibits the reaction [manganese chloride results in decreased expression of and results in decreased activity of GLUL protein]; Riluzole inhibits the reaction [manganese chloride results in decreased expression of GLUL mRNA]
CTD PMID:19615351 NCBI chr13:65,969,064...66,035,121
Ensembl chr13:66,025,630...66,035,108
JBrowse link
G Gnb4 G protein subunit beta 4 increases expression EXP manganese chloride results in increased expression of GNB4 mRNA CTD PMID:28801915 NCBI chr 2:115,360,746...115,400,680
Ensembl chr 2:115,364,918...115,400,579
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 increases expression
multiple interactions
increases secretion
EXP manganese chloride results in increased expression of GNRH1 mRNA
1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]; [manganese chloride co-treated with Calcium Chloride] results in increased secretion of GNRH1 protein; [manganese chloride results in increased chemical synthesis of Cyclic GMP] which results in increased secretion of GNRH1 protein; Bicuculline promotes the reaction [manganese chloride results in increased secretion of GNRH1 protein]; Dopamine affects the reaction [manganese chloride results in increased secretion of GNRH1 protein]; gamma-Aminobutyric Acid inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]; Haloperidol inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]; KT 5823 inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]; Methylene Blue inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]
CTD PMID:17110411 PMID:17290048 PMID:18603625 PMID:21402727 NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581
JBrowse link
G Gpnmb glycoprotein nmb increases expression EXP manganese chloride results in increased expression of GPNMB mRNA CTD PMID:28801915 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
JBrowse link
G Gpr18 G protein-coupled receptor 18 decreases expression EXP manganese chloride results in decreased expression of GPR18 mRNA CTD PMID:26745496 NCBI chr15:98,997,427...99,001,177
Ensembl chr15:98,997,259...99,001,470
JBrowse link
G Gpr34 G protein-coupled receptor 34 decreases expression EXP manganese chloride results in decreased expression of GPR34 mRNA CTD PMID:26745496 NCBI chr  X:9,104,829...9,113,796
Ensembl chr  X:9,104,565...9,148,601
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
decreases expression
ISO Melatonin affects the reaction [manganese chloride results in decreased expression of GPX1 protein] CTD PMID:24969583 PMID:25288107 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 increases methylation
decreases expression
ISO
EXP
manganese chloride results in increased methylation of GRIK3 gene
manganese chloride results in decreased expression of GRIK3 mRNA
CTD PMID:27913844 PMID:28801915 NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 decreases expression EXP manganese chloride results in decreased expression of GRIN1 mRNA; manganese chloride results in decreased expression of GRIN1 protein CTD PMID:20175136 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A decreases expression EXP manganese chloride results in decreased expression of GRIN2A mRNA; manganese chloride results in decreased expression of GRIN2A protein CTD PMID:20175136 NCBI chr10:5,630,684...6,043,341
Ensembl chr10:5,631,369...6,044,637
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B decreases expression EXP manganese chloride results in decreased expression of GRIN2B mRNA; manganese chloride results in decreased expression of GRIN2B protein CTD PMID:20175136 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases activity
decreases phosphorylation
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in decreased phosphorylation of GSK3B protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased activity of GSK3B protein]; [Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; GSK3B protein affects the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; Lithium Chloride inhibits the reaction [manganese chloride results in decreased phosphorylation of and results in increased activity of GSK3B protein]; manganese chloride results in decreased phosphorylation of and results in increased activity of GSK3B protein CTD PMID:20937724 PMID:24464479 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gskip GSK3B interacting protein increases expression EXP manganese chloride results in increased expression of GSKIP mRNA CTD PMID:28801915 NCBI chr 6:124,586,087...124,609,106
Ensembl chr 6:124,586,070...124,609,100
JBrowse link
G Gspt2 G1 to S phase transition 2 decreases expression EXP manganese chloride results in decreased expression of GSPT2 mRNA CTD PMID:28801915 NCBI chr  X:59,587,237...59,589,758
Ensembl chr  X:59,587,276...59,594,162
JBrowse link
G Gsr glutathione-disulfide reductase decreases expression
multiple interactions
ISO manganese chloride results in decreased expression of GSR mRNA
manganese chloride results in decreased expression of GSR protein
[manganese chloride results in increased abundance of Manganese] which results in decreased activity of GSR protein; Melatonin affects the reaction [manganese chloride results in decreased expression of GSR protein]; Melatonin inhibits the reaction [manganese chloride results in decreased expression of GSR protein]
CTD PMID:17175027 PMID:24969583 PMID:25288107 PMID:32445656 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gtf2h1 general transcription factor IIH subunit 1 decreases expression ISO manganese chloride results in decreased expression of GTF2H1 mRNA CTD PMID:17175027 NCBI chr 1:97,321,401...97,349,455
Ensembl chr 1:97,321,394...97,349,455
JBrowse link
G H1f1 H1.1 linker histone, cluster member decreases expression EXP manganese chloride results in decreased expression of H1F1 mRNA CTD PMID:28801915 NCBI chr17:41,366,268...41,367,011
Ensembl chr17:41,366,268...41,367,011
JBrowse link
G H1f2 H1.2 linker histone, cluster member decreases expression EXP manganese chloride results in decreased expression of H1F2 mRNA CTD PMID:28801915 NCBI chr17:41,391,106...41,392,611
Ensembl chr17:41,388,477...41,392,635
JBrowse link
G H2bu1 H2B.U histone 1 decreases expression EXP manganese chloride results in decreased expression of H2BC26 mRNA CTD PMID:28801915 NCBI chr10:43,732,737...43,733,484
Ensembl chr10:43,732,864...43,736,277
JBrowse link
G H3c1 H3 clustered histone 1 decreases expression EXP manganese chloride results in decreased expression of H3C1 mRNA CTD PMID:28801915 NCBI chr17:41,367,824...41,368,902
Ensembl chr17:41,368,386...41,368,856
JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression
multiple interactions
EXP
ISO
manganese chloride results in decreased expression of HAMP mRNA
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in decreased expression of HAMP protein]; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of HAMP protein
CTD PMID:20635692 PMID:34590183 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hapln3 hyaluronan and proteoglycan link protein 3 increases expression EXP manganese chloride results in increased expression of HAPLN3 mRNA CTD PMID:28801915 NCBI chr 1:133,046,465...133,064,665
Ensembl chr 1:133,046,467...133,080,177
JBrowse link
G Hat1 histone acetyltransferase 1 decreases expression EXP
ISO
manganese chloride results in decreased expression of HAT1 protein CTD PMID:29155171 NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517
JBrowse link
G Hdac1 histone deacetylase 1 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to HDAC1 protein]; Hesperidin inhibits the reaction [[manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to HDAC1 protein]] CTD PMID:34800614 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Hdac2 histone deacetylase 2 increases expression EXP manganese chloride results in increased expression of HDAC2 mRNA CTD PMID:29155171 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Hdac3 histone deacetylase 3 increases expression
multiple interactions
ISO
EXP
manganese chloride results in increased expression of HDAC3 mRNA; manganese chloride results in increased expression of HDAC3 protein
[manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to HDAC3 protein]; silmitasertib inhibits the reaction [[manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to HDAC3 protein]]
CTD PMID:29155171 PMID:34800614 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856
JBrowse link
G Hdac4 histone deacetylase 4 increases expression ISO
EXP
manganese chloride results in increased expression of HDAC4 mRNA; manganese chloride results in increased expression of HDAC4 protein CTD PMID:29155171 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164
JBrowse link
G Hdgfl3 HDGF like 3 increases expression EXP manganese chloride results in increased expression of HDGFL3 mRNA CTD PMID:28801915 NCBI chr 1:135,822,600...135,876,719
Ensembl chr 1:135,827,549...135,876,719
JBrowse link
G Heatr3 HEAT repeat containing 3 increases expression EXP manganese chloride results in increased expression of HEATR3 mRNA CTD PMID:28801915 NCBI chr19:18,892,477...18,930,502
Ensembl chr19:18,893,144...18,930,509
JBrowse link
G Heph hephaestin increases expression ISO manganese chloride results in increased expression of HEPH mRNA CTD PMID:17175027 NCBI chr  X:61,151,131...61,402,980
Ensembl chr  X:61,296,345...61,402,980
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 increases expression EXP manganese chloride results in increased expression of HEY1 mRNA CTD PMID:28801915 NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312
JBrowse link
G Hfe homeostatic iron regulator multiple interactions
decreases response to substance
ISO HFE gene mutant form inhibits the reaction [manganese chloride results in decreased activity of SOD1 protein]
HFE gene mutant form results in decreased susceptibility to manganese chloride
CTD PMID:25874029 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions
decreases hydroxylation
increases stability
decreases degradation
decreases expression
ISO
EXP
manganese chloride results in increased expression of HIF1A mRNA; manganese chloride results in increased expression of HIF1A protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of HIF1A protein]; [manganese chloride results in decreased activity of P4HTM protein] which results in decreased degradation of HIF1A protein; [manganese chloride results in decreased activity of P4HTM protein] which results in decreased hydroxylation of HIF1A protein; Ascorbic Acid inhibits the reaction [manganese chloride results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [manganese chloride results in increased stability of HIF1A protein]; HIF1A mutant form inhibits the reaction [manganese chloride results in increased secretion of VEGFA protein]; Iron inhibits the reaction [manganese chloride results in increased expression of HIF1A protein]; manganese chloride inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]]; manganese chloride results in increased expression of and results in increased activity of and results in increased stability of HIF1A protein; pyrazolanthrone inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of and results in increased stability of HIF1A protein]; SB 203580 inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of and results in increased stability of HIF1A protein]; SB 203580 inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of HIF1A protein]; VHL protein affects the reaction [manganese chloride results in increased expression of HIF1A protein]
manganese chloride results in decreased degradation of HIF1A protein
manganese chloride results in decreased expression of HIF1A mRNA
[[manganese chloride results in increased abundance of Manganese] which co-treated with Ethanol] results in increased expression of HIF1A protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of HIF1A protein
CTD PMID:17175027 PMID:17467022 PMID:19074761 PMID:19263519 PMID:20152896 More... NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor decreases expression ISO manganese chloride results in decreased expression of HIF1AN mRNA CTD PMID:17175027 NCBI chr 1:243,419,175...243,440,464
Ensembl chr 1:243,419,194...243,434,327
JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated increases expression EXP manganese chloride results in increased expression of HILPDA mRNA CTD PMID:22281203 NCBI chr 4:57,871,076...57,875,206
Ensembl chr 4:57,871,110...57,874,557
JBrowse link
G Hipk3 homeodomain interacting protein kinase 3 decreases expression EXP manganese chloride results in decreased expression of HIPK3 mRNA CTD PMID:28801915 NCBI chr 3:90,796,980...90,866,701
Ensembl chr 3:90,800,296...90,867,759
JBrowse link
G Hist1h2an histone cluster 1, H2an decreases expression EXP manganese chloride results in decreased expression of HIST1H2AN mRNA CTD PMID:28801915 NCBI chr17:41,534,653...41,535,259
Ensembl chr17:41,534,691...41,539,869
JBrowse link
G Hist1h2bc histone cluster 1, H2bc decreases expression EXP manganese chloride results in decreased expression of HIST1H2BC mRNA CTD PMID:28801915 NCBI chr17:42,692,335...42,696,860
Ensembl chr17:42,694,723...42,696,642
JBrowse link
G Hist1h2bl histone cluster 1 H2B family member l decreases expression EXP manganese chloride results in decreased expression of HIST1H2BL mRNA CTD PMID:28801915 NCBI chr17:42,708,646...42,709,435 JBrowse link
G Hist1h2bq histone cluster 1 H2B family member Q decreases expression EXP manganese chloride results in decreased expression of HIST1H2BQ mRNA CTD PMID:28801915 NCBI chr17:41,432,100...41,441,487
Ensembl chr17:41,429,164...41,442,153
JBrowse link
G Hist2h2aa2 histone cluster 2 H2A family member A2 decreases expression EXP manganese chloride results in decreased expression of HIST2H2AA2 mRNA CTD PMID:28801915 NCBI chr 2:183,801,369...183,801,987 JBrowse link
G Hist3h2ba histone cluster 3, H2ba decreases expression EXP manganese chloride results in decreased expression of HIST3H2BA mRNA CTD PMID:28801915 NCBI chr10:43,725,836...43,726,465
Ensembl chr10:43,724,930...43,727,107
JBrowse link
G Hmbox1 homeobox containing 1 decreases expression EXP manganese chloride results in decreased expression of HMBOX1 mRNA CTD PMID:28801915 NCBI chr15:39,067,805...39,200,633
Ensembl chr15:39,067,804...39,200,323
JBrowse link
G Hmcn2 hemicentin 2 increases expression EXP manganese chloride results in increased expression of HMCN2 mRNA CTD PMID:28801915 NCBI chr 3:14,588,353...14,738,320
Ensembl chr 3:14,588,662...14,738,025
JBrowse link
G Hmgb1 high mobility group box 1 increases expression
multiple interactions
ISO manganese chloride results in increased expression of HMGB1 mRNA
corynoxine B affects the reaction [manganese chloride affects the reaction [HMGB1 protein binds to BECN1 protein]]; corynoxine B inhibits the reaction [manganese chloride promotes the reaction [HMGB1 protein binds to SNCA protein]]; manganese chloride affects the reaction [HMGB1 protein binds to BECN1 protein]; manganese chloride promotes the reaction [HMGB1 protein binds to SNCA protein]; manganese chloride results in increased expression of and affects the localization of HMGB1 protein
CTD PMID:30578841 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 decreases expression EXP manganese chloride results in decreased expression of HMGCS2 mRNA CTD PMID:26745496 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
JBrowse link
G Hmox1 heme oxygenase 1 affects response to substance
multiple interactions
increases expression
ISO
EXP
HMOX1 protein affects the susceptibility to manganese chloride
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased expression of HMOX1 protein; anacardic acid promotes the reaction [manganese chloride results in increased expression of HMOX1 mRNA]; GW 506033X promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of HMOX1 protein]; lactacystin promotes the reaction [manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; lactacystin promotes the reaction [manganese chloride results in increased expression of HMOX1 protein]; manganese chloride promotes the reaction [[NFE2L2 protein binds to HMOX1 promoter] which results in increased expression of HMOX1 mRNA]; manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]; SB 203580 inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; tin protoporphyrin IX inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; trichostatin A promotes the reaction [manganese chloride results in increased expression of HMOX1 mRNA]; trichostatin A promotes the reaction [manganese chloride results in increased expression of HMOX1 protein]
HMOX1 protein inhibits the reaction [manganese chloride results in increased abundance of Hydrogen Peroxide]; manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 mRNA]; manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 protein]; Melatonin inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]
manganese chloride results in increased expression of HMOX1 mRNA; manganese chloride results in increased expression of HMOX1 protein
CTD PMID:21107535 PMID:21384399 PMID:21963524 PMID:22281203 PMID:25288107 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hoxb9 homeo box B9 decreases expression ISO manganese chloride results in decreased expression of HOXB9 mRNA CTD PMID:17175027 NCBI chr10:81,237,312...81,240,818
Ensembl chr10:81,237,312...81,240,818
JBrowse link
G Hoxd4 homeo box D4 increases expression EXP manganese chloride results in increased expression of HOXD4 mRNA CTD PMID:28801915 NCBI chr 3:59,614,464...59,634,042
Ensembl chr 3:59,614,464...59,631,528
JBrowse link
G Hpx hemopexin decreases expression EXP manganese chloride results in decreased expression of HPX mRNA CTD PMID:28801915 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
JBrowse link
G Hrh1 histamine receptor H 1 decreases methylation ISO manganese chloride results in decreased methylation of HRH1 gene CTD PMID:27913844 NCBI chr 4:147,564,781...147,649,353
Ensembl chr 4:147,645,995...147,647,455
JBrowse link
G Hrk harakiri, BCL2 interacting protein increases expression
decreases methylation
EXP manganese chloride results in increased expression of HRK mRNA
manganese chloride results in decreased methylation of HRK gene
CTD PMID:28801915 NCBI chr12:38,387,484...38,409,652 JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases expression EXP manganese chloride results in increased expression of HSD11B1 mRNA CTD PMID:28801915 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions
increases expression
EXP SNCA protein promotes the reaction [manganese chloride results in increased expression of HSP90B1 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of HSP90B1 protein]
manganese chloride results in increased expression of HSP90B1 mRNA; manganese chloride results in increased expression of HSP90B1 protein
CTD PMID:23934647 PMID:23948121 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like increases expression EXP manganese chloride results in increased expression of HSPA4L mRNA CTD PMID:28801915 NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
EXP [manganese chloride results in increased abundance of Manganese] which results in increased expression of HSPA5 mRNA; SNCA protein promotes the reaction [manganese chloride results in increased expression of HSPA5 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of HSPA5 protein]
manganese chloride results in increased expression of HSPA5 mRNA; manganese chloride results in increased expression of HSPA5 protein
CTD PMID:23934647 PMID:23948121 PMID:25732873 PMID:32574669 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspb8 heat shock protein family B (small) member 8 decreases expression EXP manganese chloride results in decreased expression of HSPB8 mRNA CTD PMID:28801915 NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
JBrowse link
G Htra1 HtrA serine peptidase 1 increases expression EXP manganese chloride results in increased expression of HTRA1 mRNA CTD PMID:28801915 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379
JBrowse link
G Htt huntingtin affects response to substance ISO HTT affects the susceptibility to manganese chloride CTD PMID:22363539 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
decreases expression
ISO
EXP
manganese chloride inhibits the reaction [CCL2 protein results in increased expression of ICAM1 protein]; manganese chloride inhibits the reaction [Glucose results in increased expression of ICAM1 protein]
manganese chloride results in decreased expression of ICAM1 protein
CTD PMID:23329836 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO manganese chloride results in increased expression of ID1 mRNA CTD PMID:17467022 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression
decreases expression
ISO
EXP
manganese chloride results in increased expression of ID2 mRNA
manganese chloride results in decreased expression of ID2 mRNA
CTD PMID:17175027 PMID:28801915 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
EXP
ISO
manganese chloride results in increased expression of IFNG protein
manganese chloride promotes the reaction [[TNF protein co-treated with IFNG protein] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]]; manganese chloride promotes the reaction [TNF protein co-treated with and results in increased chemical synthesis of IFNG protein co-treated with and results in increased chemical synthesis of Nitric Oxide]; manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 mRNA]; manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 protein]; NFKBIA protein affects the reaction [manganese chloride promotes the reaction [TNF protein co-treated with and results in increased chemical synthesis of IFNG protein co-treated with and results in increased chemical synthesis of Nitric Oxide]]; NFKBIA protein affects the reaction [manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 mRNA]]; NFKBIA protein affects the reaction [manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 protein]]
CTD PMID:16168523 PMID:20798247 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression EXP manganese chloride results in increased expression of IGF1 mRNA CTD PMID:21402727 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression
decreases expression
EXP manganese chloride results in increased expression of IGF1R protein
manganese chloride results in decreased expression of IGF1R mRNA
CTD PMID:19276553 PMID:21402727 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Igf2 insulin-like growth factor 2 decreases methylation ISO manganese chloride results in decreased methylation of IGF2 gene CTD PMID:27913844 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Igf2r insulin-like growth factor 2 receptor decreases expression EXP manganese chloride results in decreased expression of IGF2R mRNA CTD PMID:19276553 NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 increases expression EXP manganese chloride results in increased expression of IGFBP5 mRNA CTD PMID:28801915 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO IKBKB gene mutant form results in increased susceptibility to [manganese chloride results in increased abundance of Manganese]
[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of IKBKB protein; Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of IKBKB protein]; alpha-Tocopherol inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of IKBKB protein]; IkK-16 compound inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of IKBKB protein]
CTD PMID:32692843 PMID:34310962 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il12a interleukin 12A increases expression
multiple interactions
ISO manganese chloride results in increased expression of IL12A mRNA
manganese chloride results in increased expression of [IL12A protein binds to IL12B protein]
manganese chloride promotes the reaction [SNCA protein results in increased expression of [IL12A protein binds to IL12B protein]]
CTD PMID:17175027 PMID:28539244 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B multiple interactions
increases expression
ISO manganese chloride promotes the reaction [SNCA protein results in increased expression of [IL12A protein binds to IL12B protein]]
manganese chloride results in increased expression of [IL12A protein binds to IL12B protein]
manganese chloride results in increased expression of IL12B mRNA
CTD PMID:28539244 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il18 interleukin 18 multiple interactions
increases expression
ISO acetovanillone analog inhibits the reaction [manganese chloride results in increased expression of IL18 mRNA] CTD PMID:28539244 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha increases expression EXP manganese chloride results in increased expression of IL1A mRNA CTD PMID:25219578 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
decreases expression
EXP
ISO
manganese chloride results in increased expression of IL1B protein
[manganese chloride results in increased abundance of Manganese] which results in increased expression of IL1B protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of IL1B protein]; Minocycline inhibits the reaction [manganese chloride results in increased expression of IL1B protein]
[Lipopolysaccharides co-treated with manganese chloride] results in increased expression of IL1B protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL1B mRNA; [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL1B protein; acetovanillone analog inhibits the reaction [manganese chloride results in increased expression of IL1B mRNA]
manganese chloride results in decreased expression of IL1B mRNA
[manganese chloride co-treated with SNCA protein] results in increased expression of IL1B mRNA; [manganese chloride co-treated with SNCA protein] results in increased expression of IL1B protein
CTD PMID:15601679 PMID:18836210 PMID:27427241 PMID:28539244 PMID:33314588 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1r1 interleukin 1 receptor type 1 increases expression EXP manganese chloride results in increased expression of IL1R1 mRNA CTD PMID:28801915 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Il1r2 interleukin 1 receptor type 2 increases expression EXP manganese chloride results in increased expression of IL1R2 mRNA CTD PMID:28801915 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 decreases expression
increases expression
EXP manganese chloride results in decreased expression of IL1RL1 mRNA
manganese chloride results in increased expression of IL1RL1 mRNA
CTD PMID:26745496 PMID:28801915 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression EXP manganese chloride results in increased expression of IL1RN mRNA CTD PMID:28801915 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il23a interleukin 23 subunit alpha increases expression EXP manganese chloride results in increased expression of IL23A mRNA CTD PMID:28801915 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
JBrowse link
G Il36rn interleukin 36 receptor antagonist increases expression EXP manganese chloride results in increased expression of IL36RN mRNA CTD PMID:28801915 NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL4 mRNA; [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL4 protein CTD PMID:34018660 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
decreases expression
increases secretion
ISO
EXP
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL6 mRNA; [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL6 protein; Buthionine Sulfoximine inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; Lipopolysaccharides promotes the reaction [manganese chloride results in increased expression of IL6 protein]; manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]; manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein]; manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; tin protoporphyrin IX inhibits the reaction [manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; zinc protoporphyrin inhibits the reaction [manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein]]
manganese chloride results in increased expression of IL6 mRNA
manganese chloride results in increased expression of IL6 mRNA; manganese chloride results in increased expression of IL6 protein
manganese chloride results in decreased expression of IL6 mRNA
manganese chloride results in increased secretion of IL6 protein
manganese chloride promotes the reaction [SNCA protein results in increased expression of IL6 mRNA]
CTD PMID:15601679 PMID:17065364 PMID:19815061 PMID:21963524 PMID:25219578 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il7 interleukin 7 increases expression ISO manganese chloride results in increased expression of IL7 mRNA CTD PMID:17175027 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
JBrowse link
G Ins2 insulin 2 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] inhibits the reaction [Glucose results in increased secretion of INS protein] CTD PMID:31555879 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Insig1 insulin induced gene 1 decreases expression
increases methylation
EXP manganese chloride results in decreased expression of INSIG1 mRNA
manganese chloride results in increased methylation of INSIG1 gene
CTD PMID:28801915 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Insr insulin receptor decreases expression
increases phosphorylation
increases expression
EXP manganese chloride results in decreased expression of INSR mRNA
manganese chloride results in increased phosphorylation of INSR protein
manganese chloride results in increased expression of INSR mRNA
CTD PMID:2475105 PMID:19276553 PMID:28801915 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Ints2 integrator complex subunit 2 decreases expression EXP manganese chloride results in decreased expression of INTS2 mRNA CTD PMID:28801915 NCBI chr10:71,031,647...71,079,138
Ensembl chr10:71,031,647...71,079,076
JBrowse link
G Iqcg IQ motif containing G increases expression EXP manganese chloride results in increased expression of IQCG mRNA CTD PMID:28801915 NCBI chr11:67,730,117...67,771,170
Ensembl chr11:67,730,247...67,771,168
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 increases expression EXP manganese chloride results in increased expression of IQGAP1 mRNA CTD PMID:28801915 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
JBrowse link
G Ireb2 iron responsive element binding protein 2 decreases activity
increases activity
EXP manganese chloride results in decreased activity of IREB2 protein
manganese chloride results in increased activity of IREB2 protein
CTD PMID:15893546 PMID:16568477 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
JBrowse link
G Irf2 interferon regulatory factor 2 decreases expression EXP manganese chloride results in decreased expression of IRF2 mRNA CTD PMID:28801915 NCBI chr16:45,439,215...45,550,054
Ensembl chr16:45,439,225...45,550,024
JBrowse link
G Ism1 isthmin 1 increases expression EXP manganese chloride results in increased expression of ISM1 mRNA CTD PMID:28801915 NCBI chr 3:127,023,322...127,102,228
Ensembl chr 3:127,021,865...127,101,894
JBrowse link
G Itga10 integrin subunit alpha 10 increases expression EXP manganese chloride results in increased expression of ITGA10 mRNA CTD PMID:28801915 NCBI chr 2:184,182,869...184,202,172
Ensembl chr 2:184,182,869...184,202,172
JBrowse link
G Itga2b integrin subunit alpha 2b multiple interactions ISO manganese chloride inhibits the reaction [TLN1 protein mutant form results in decreased activity of [ITGB3 protein binds to ITGA2B protein]]; manganese chloride results in increased activity of [ITGB3 protein binds to ITGA2B protein] CTD PMID:20971947 NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168
JBrowse link
G Itga3 integrin subunit alpha 3 increases expression ISO manganese chloride results in increased expression of ITGA3 mRNA CTD PMID:17175027 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
JBrowse link
G Itga8 integrin subunit alpha 8 increases expression
increases methylation
EXP manganese chloride results in increased expression of ITGA8 mRNA
manganese chloride results in increased methylation of ITGA8 gene
CTD PMID:28801915 NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510
JBrowse link
G Itgam integrin subunit alpha M increases expression EXP manganese chloride results in increased expression of ITGAM protein CTD PMID:12106697 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itgav integrin subunit alpha V multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; [AG 1879 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; [CGP 77675 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; arginyl-glycyl-aspartic acid inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]; wortmannin inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]] CTD PMID:15213856 NCBI chr 3:68,838,524...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Itgb3 integrin subunit beta 3 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; [AG 1879 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; [CGP 77675 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; arginyl-glycyl-aspartic acid inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]; Wortmannin inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]
manganese chloride inhibits the reaction [TLN1 protein mutant form results in decreased activity of [ITGB3 protein binds to ITGA2B protein]]; manganese chloride results in increased activity of [ITGB3 protein binds to ITGA2B protein]
CTD PMID:15213856 PMID:20971947 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Itgb5 integrin subunit beta 5 increases expression ISO manganese chloride results in increased expression of ITGB5 mRNA CTD PMID:17175027 NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472
JBrowse link
G Itgb6 integrin subunit beta 6 decreases methylation
increases methylation
increases expression
ISO
EXP
manganese chloride results in decreased methylation of ITGB6 gene
manganese chloride results in increased methylation of ITGB6 gene
manganese chloride results in increased expression of ITGB6 mRNA
CTD PMID:27913844 PMID:28801915 NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671
JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 multiple interactions ISO manganese chloride promotes the reaction [ITIH1 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr16:6,122,246...6,136,363
Ensembl chr16:6,122,248...6,136,363
JBrowse link
G Itih2 inter-alpha-trypsin inhibitor heavy chain 2 multiple interactions ISO manganese chloride promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr17:68,375,518...68,411,849
Ensembl chr17:68,375,567...68,411,841
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases phosphorylation
EXP manganese chloride results in increased expression of and results in increased phosphorylation of JUN protein; pyrazolanthrone inhibits the reaction [manganese chloride results in increased phosphorylation of JUN protein] CTD PMID:9751194 PMID:15342272 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kcng1 potassium voltage-gated channel modifier subfamily G member 1 increases expression EXP manganese chloride results in increased expression of KCNG1 mRNA CTD PMID:28801915 NCBI chr 3:156,960,717...156,992,877
Ensembl chr 3:156,973,156...156,992,635
JBrowse link
G Kcnh4 potassium voltage-gated channel subfamily H member 4 decreases expression EXP manganese chloride results in decreased expression of KCNH4 mRNA CTD PMID:28801915 NCBI chr10:85,668,332...85,688,166
Ensembl chr10:85,668,337...85,688,158
JBrowse link
G Kcnh6 potassium voltage-gated channel subfamily H member 6 increases expression EXP manganese chloride results in increased expression of KCNH6 mRNA CTD PMID:28801915 NCBI chr10:90,949,240...90,970,746
Ensembl chr10:90,949,846...90,970,701
JBrowse link
G Kcnip3 potassium voltage-gated channel interacting protein 3 increases expression ISO manganese chloride results in increased expression of KCNIP3 mRNA CTD PMID:17175027 NCBI chr 3:114,677,027...114,742,923
Ensembl chr 3:114,677,030...114,743,556
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of KCNJ11 protein CTD PMID:32659473 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 increases expression ISO manganese chloride results in increased expression of KCNJ3 mRNA CTD PMID:17175027 NCBI chr 3:39,944,896...40,106,646
Ensembl chr 3:39,945,351...40,109,124
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of KCNJ8 protein CTD PMID:32659473 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603
JBrowse link
G Kcnk12 potassium two pore domain channel subfamily K member 12 decreases expression EXP manganese chloride results in decreased expression of KCNK12 mRNA CTD PMID:28801915 NCBI chr 6:6,740,147...6,790,664
Ensembl chr 6:6,739,991...6,790,661
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 increases expression EXP manganese chloride results in increased expression of KCNQ1 mRNA CTD PMID:28801915 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 increases expression EXP manganese chloride results in increased expression of KCNQ2 mRNA CTD PMID:28801915 NCBI chr 3:168,194,776...168,253,831
Ensembl chr 3:168,195,357...168,275,071
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 affects expression
multiple interactions
ISO manganese chloride affects the expression of KEAP1 protein
Melatonin affects the reaction [manganese chloride affects the expression of KEAP1 protein]
CTD PMID:25288107 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Kera keratocan increases expression EXP manganese chloride results in increased expression of KERA mRNA CTD PMID:26745496 NCBI chr 7:32,397,382...32,404,837
Ensembl chr 7:32,397,382...32,404,837
JBrowse link
G Kif3b kinesin family member 3B increases expression EXP manganese chloride results in increased expression of KIF3B mRNA CTD PMID:28801915 NCBI chr 3:141,758,466...141,798,012
Ensembl chr 3:141,758,466...141,797,963
JBrowse link
G Kif5c kinesin family member 5C increases expression EXP manganese chloride results in increased expression of KIF5C mRNA CTD PMID:28801915 NCBI chr 3:34,032,082...34,185,597
Ensembl chr 3:34,032,105...34,182,413
JBrowse link
G Kiss1r KISS1 receptor increases expression EXP manganese chloride results in increased expression of KISS1R mRNA CTD PMID:28801915 NCBI chr 7:9,785,135...9,790,283
Ensembl chr 7:9,785,135...9,788,793
JBrowse link
G Klf2 Kruppel-like factor 2 increases expression EXP manganese chloride results in increased expression of KLF2 mRNA CTD PMID:28801915 NCBI chr16:17,521,773...17,523,723
Ensembl chr16:17,514,552...17,523,944
JBrowse link
G Klf4 Kruppel like factor 4 increases expression ISO manganese chloride results in increased expression of KLF4 mRNA CTD PMID:17175027 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Klf5 Kruppel-like factor 5 decreases expression
increases expression
decreases methylation
ISO
EXP
manganese chloride results in decreased expression of KLF5 mRNA
manganese chloride results in increased expression of KLF5 mRNA
manganese chloride results in decreased methylation of KLF5 gene
CTD PMID:17467022 PMID:28801915 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
JBrowse link
G Klf9 Kruppel-like factor 9 decreases expression ISO manganese chloride results in decreased expression of KLF9 mRNA CTD PMID:17175027 NCBI chr 1:220,700,108...220,725,029
Ensembl chr 1:220,700,108...220,725,037
JBrowse link
G Klhdc8a kelch domain containing 8A increases expression EXP manganese chloride results in increased expression of KLHDC8A mRNA CTD PMID:28801915 NCBI chr13:43,735,702...43,744,277
Ensembl chr13:43,736,192...43,744,277
JBrowse link
G Kng2 kininogen 2 decreases expression EXP manganese chloride results in decreased expression of KNG1 mRNA CTD PMID:28801915 NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971
JBrowse link
G Krt7 keratin 7 increases expression EXP manganese chloride results in increased expression of KRT7 mRNA CTD PMID:28801915 NCBI chr 7:132,528,863...132,545,052
Ensembl chr 7:132,528,895...132,545,052
JBrowse link
G Krt76 keratin 76 increases expression EXP manganese chloride results in increased expression of KRT76 mRNA CTD PMID:28801915 NCBI chr 7:133,016,990...133,025,414
Ensembl chr 7:133,016,992...133,025,496
JBrowse link
G Krt79 keratin 79 decreases expression EXP manganese chloride results in decreased expression of KRT79 mRNA CTD PMID:28801915 NCBI chr 7:133,056,710...133,067,750
Ensembl chr 7:133,056,709...133,067,705
JBrowse link
G Krt81 keratin 81 increases expression EXP manganese chloride results in increased expression of KRT81 mRNA CTD PMID:28801915 NCBI chr 7:132,577,112...132,582,238
Ensembl chr 7:132,576,492...132,582,170
JBrowse link
G Krt83 keratin 83 increases expression EXP manganese chloride results in increased expression of KRT83 mRNA CTD PMID:28801915 NCBI chr 7:132,547,388...132,554,978
Ensembl chr 7:132,548,141...132,554,978
JBrowse link
G Krtap1-3 keratin associated protein 1-3 increases expression EXP manganese chloride results in increased expression of KRTAP1-3 mRNA CTD PMID:28801915 NCBI chr10:84,552,873...84,553,394
Ensembl chr10:84,552,873...84,553,394
JBrowse link
G Lacc1 laccase domain containing 1 increases expression EXP manganese chloride results in increased expression of LACC1 mRNA CTD PMID:28801915 NCBI chr15:52,390,267...52,407,630
Ensembl chr15:52,395,183...52,407,545
JBrowse link
G Lcat lecithin cholesterol acyltransferase increases expression EXP manganese chloride results in increased expression of LCAT mRNA CTD PMID:28801915 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase multiple interactions ISO [manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein; Tetradecanoylphorbol Acetate inhibits the reaction [[manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein] CTD PMID:8662792 NCBI chr 5:141,888,319...141,916,992
Ensembl chr 5:141,888,326...141,903,794
JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 increases expression EXP manganese chloride results in increased expression of LDLRAD4 mRNA CTD PMID:28801915 NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238
JBrowse link
G Lgals3 galectin 3 increases expression EXP manganese chloride results in increased expression of LGALS3 mRNA CTD PMID:28801915 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Lgi4 leucine-rich repeat LGI family, member 4 increases expression EXP manganese chloride results in increased expression of LGI4 mRNA CTD PMID:28801915 NCBI chr 1:86,294,539...86,305,909
Ensembl chr 1:86,295,074...86,304,874
JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 decreases expression EXP manganese chloride results in decreased expression of LGR4 mRNA CTD PMID:28801915 NCBI chr 3:96,447,385...96,550,006
Ensembl chr 3:96,447,858...96,548,899
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions
decreases expression
EXP Quercetin inhibits the reaction [manganese chloride results in decreased expression of LHB protein] CTD PMID:28040552 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Lhfpl2 LHFPL tetraspan subfamily member 2 increases expression EXP manganese chloride results in increased expression of LHFPL2 mRNA CTD PMID:28801915 NCBI chr 2:25,281,771...25,428,128
Ensembl chr 2:25,281,901...25,427,950
JBrowse link
G Lhx1 LIM homeobox 1 decreases expression EXP manganese chloride results in decreased expression of LHX1 mRNA CTD PMID:28801915 NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617
JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression EXP manganese chloride results in increased expression of LIF mRNA CTD PMID:28801915 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Lman2 lectin, mannose-binding 2 increases expression ISO manganese chloride results in increased expression of LMAN2 mRNA CTD PMID:17175027 NCBI chr17:9,269,236...9,286,923
Ensembl chr17:9,269,022...9,287,265
JBrowse link
G Lmod2 leiomodin 2 decreases expression EXP manganese chloride results in decreased expression of LMOD2 mRNA CTD PMID:28801915 NCBI chr 4:53,067,428...53,075,124
Ensembl chr 4:53,067,428...53,075,120
JBrowse link
G Lox lysyl oxidase decreases expression EXP manganese chloride results in decreased expression of LOX mRNA CTD PMID:28801915 NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Lpal2 lipoprotein(a) like 2, pseudogene decreases expression EXP manganese chloride results in decreased expression of LPAL2 mRNA CTD PMID:28801915 NCBI chr 4:165,207,378...165,264,321
Ensembl chr 4:165,207,328...165,264,340
JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 decreases expression EXP manganese chloride results in decreased expression of LPAR1 mRNA CTD PMID:28801915 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895
JBrowse link
G Lpcat4 lysophosphatidylcholine acyltransferase 4 decreases expression EXP manganese chloride results in decreased expression of LPCAT4 mRNA CTD PMID:28801915 NCBI chr 3:99,044,729...99,052,963
Ensembl chr 3:99,044,729...99,052,875
JBrowse link
G Lpin1 lipin 1 decreases expression EXP manganese chloride results in decreased expression of LPIN1 mRNA CTD PMID:28801915 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Lrat lecithin retinol acyltransferase increases expression EXP manganese chloride results in increased expression of LRAT mRNA CTD PMID:26745496 NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619
JBrowse link
G Lrp2 LDL receptor related protein 2 decreases expression EXP manganese chloride results in decreased expression of LRP2 mRNA CTD PMID:28801915 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708
JBrowse link
G Lrp8 LDL receptor related protein 8 increases expression ISO manganese chloride results in increased expression of LRP8 mRNA CTD PMID:22407947 NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352
JBrowse link
G Lrrc10b leucine rich repeat containing 10B increases methylation EXP manganese chloride results in increased methylation of LRRC10B gene CTD PMID:28801915 NCBI chr 1:207,096,471...207,097,699
Ensembl chr 1:207,022,919...207,098,045
JBrowse link
G Lrrc15 leucine rich repeat containing 15 increases expression EXP manganese chloride results in increased expression of LRRC15 mRNA CTD PMID:28801915 NCBI chr11:70,469,775...70,484,268
Ensembl chr11:70,469,804...70,484,267
JBrowse link
G Lrrc8b leucine rich repeat containing 8 VRAC subunit B increases expression EXP manganese chloride results in increased expression of LRRC8B mRNA CTD PMID:28801915 NCBI chr14:4,350,462...4,416,336
Ensembl chr14:4,354,508...4,416,311
JBrowse link
G Lrrk1 leucine-rich repeat kinase 1 increases expression EXP manganese chloride results in increased expression of LRRK1 mRNA CTD PMID:28801915 NCBI chr 1:119,844,360...119,972,885
Ensembl chr 1:119,845,146...119,979,734
JBrowse link
G Ly6g5b lymphocyte antigen 6 family member G5B increases expression EXP manganese chloride results in increased expression of LY6G5B mRNA CTD PMID:28801915 NCBI chr20:3,705,464...3,707,830
Ensembl chr20:3,706,124...3,707,133
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase decreases methylation ISO manganese chloride results in decreased methylation of LYN gene CTD PMID:27913844 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Lypd6b LY6/PLAUR domain containing 6B decreases expression EXP manganese chloride results in decreased expression of LYPD6B mRNA CTD PMID:28801915 NCBI chr 3:34,199,101...34,360,770
Ensembl chr 3:34,199,599...34,360,770
JBrowse link
G Lyrm7 LYR motif containing 7 increases expression EXP manganese chloride results in increased expression of LYRM7 mRNA CTD PMID:28801915 NCBI chr10:38,964,299...38,983,628
Ensembl chr10:38,964,311...38,983,601
JBrowse link
G Lyrm9 LYR motif containing 9 increases expression EXP manganese chloride results in increased expression of LYRM9 mRNA CTD PMID:28801915 NCBI chr10:63,725,718...63,739,772
Ensembl chr10:63,725,743...63,739,772
JBrowse link
G Macrod2 mono-ADP ribosylhydrolase 2 increases expression EXP manganese chloride results in increased expression of MACROD2 mRNA CTD PMID:28801915 NCBI chr 3:127,720,066...129,737,511
Ensembl chr 3:127,720,181...129,734,492
JBrowse link
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 increases expression EXP manganese chloride results in increased expression of MADCAM1 mRNA CTD PMID:28801915 NCBI chr 7:10,036,301...10,039,703
Ensembl chr 7:10,036,301...10,039,703
JBrowse link
G Maff MAF bZIP transcription factor F increases expression EXP manganese chloride results in increased expression of MAFF mRNA CTD PMID:28801915 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Mageb7 MAGE family member B7 increases expression EXP manganese chloride results in increased expression of MAGEB7 mRNA CTD PMID:28801915 NCBI chr  X:50,965,774...50,969,455
Ensembl chr  X:50,966,208...50,967,245
JBrowse link
G Mall mal, T-cell differentiation protein-like decreases expression EXP manganese chloride results in decreased expression of MALL mRNA CTD PMID:26745496 NCBI chr 3:114,927,897...114,950,840
Ensembl chr 3:114,927,897...114,950,785
JBrowse link
G Map2 microtubule-associated protein 2 decreases expression EXP manganese chloride results in decreased expression of MAP2 mRNA CTD PMID:28801915 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 decreases methylation ISO manganese chloride results in decreased methylation of MAP2K3 gene CTD PMID:27913844 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 increases phosphorylation EXP manganese chloride results in increased phosphorylation of MAP2K4 protein CTD PMID:9751194 PMID:15342272 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 increases phosphorylation EXP manganese chloride results in increased phosphorylation of MAP3K11 protein CTD PMID:15342272 NCBI chr 1:202,975,353...202,988,655
Ensembl chr 1:202,975,353...202,988,652
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 increases methylation ISO manganese chloride results in increased methylation of MAP3K7 gene CTD PMID:27913844 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 decreases expression EXP manganese chloride results in decreased expression of MAP4K3 mRNA CTD PMID:28801915 NCBI chr 6:14,276,623...14,446,321
Ensembl chr 6:14,277,121...14,446,334
JBrowse link
G Map7 microtubule-associated protein 7 increases expression EXP manganese chloride results in increased expression of MAP7 mRNA CTD PMID:28801915 NCBI chr 1:14,910,433...15,037,574
Ensembl chr 1:14,910,551...15,037,574
JBrowse link
G Map7d2 MAP7 domain containing 2 increases methylation
decreases expression
EXP manganese chloride results in increased methylation of MAP7D2 gene
manganese chloride results in decreased expression of MAP7D2 mRNA
CTD PMID:28801915 NCBI chr  X:35,372,453...35,488,073
Ensembl chr  X:35,372,700...35,488,091
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases activity
increases phosphorylation
decreases phosphorylation
EXP
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK1 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK1 protein; GW 506033X promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK1 protein]; manganese chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein; pyrazolanthrone promotes the reaction [manganese chloride results in increased phosphorylation of MAPK1 protein]; Resveratrol inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK1 protein]
manganese chloride results in increased activity of MAPK1 protein
manganese chloride results in decreased phosphorylation of MAPK1 protein
[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK1 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK1 protein]
NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK1 protein]
CTD PMID:15010209 PMID:15342272 PMID:16787641 PMID:19084589 PMID:20152896 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 increases expression EXP manganese chloride results in increased expression of MAPK11 mRNA CTD PMID:28801915 NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395
JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation
increases expression
ISO manganese chloride results in increased phosphorylation of MAPK14 protein
manganese chloride results in increased expression of MAPK14 mRNA
CTD PMID:15737199 PMID:17467022 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases activity
increases phosphorylation
decreases phosphorylation
EXP
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK3 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK3 protein; GW 506033X promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK3 protein]; manganese chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein; pyrazolanthrone promotes the reaction [manganese chloride results in increased phosphorylation of MAPK3 protein]; Resveratrol inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK3 protein]
manganese chloride results in increased activity of MAPK3 protein
manganese chloride results in decreased phosphorylation of MAPK3 protein
NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK3 protein]
[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK3 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK3 protein]
CTD PMID:15010209 PMID:15342272 PMID:16787641 PMID:19084589 PMID:20152896 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases activity
increases phosphorylation
increases methylation
multiple interactions
ISO
EXP
manganese chloride results in increased activity of MAPK8 protein
manganese chloride results in increased phosphorylation of MAPK8 protein
manganese chloride results in increased methylation of MAPK8 gene
[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein; pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein]
CTD PMID:19084589 PMID:20152896 PMID:24324973 PMID:27913844 PMID:30951808 More... NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases activity
increases phosphorylation
ISO manganese chloride results in increased activity of MAPK9 protein
manganese chloride results in increased phosphorylation of MAPK9 protein
CTD PMID:19084589 PMID:20152896 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions
increases phosphorylation
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; [Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; GSK3B protein affects the reaction [manganese chloride results in increased phosphorylation of MAPT protein] CTD PMID:20937724 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Masp1 MBL associated serine protease 1 decreases methylation ISO manganese chloride results in decreased methylation of MASP1 gene CTD PMID:27913844 NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974
JBrowse link
G Matn3 matrilin 3 decreases expression EXP manganese chloride results in decreased expression of MATN3 mRNA CTD PMID:28801915 NCBI chr 6:31,748,383...31,768,101
Ensembl chr 6:31,748,474...31,768,101
JBrowse link
G Mbp myelin basic protein increases expression ISO manganese chloride results in increased expression of MBP mRNA CTD PMID:17175027 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
JBrowse link
G Mcf2l MCF.2 cell line derived transforming sequence-like increases expression ISO manganese chloride results in increased expression of MCF2L mRNA CTD PMID:15295902 NCBI chr16:76,507,133...76,652,893
Ensembl chr16:76,507,133...76,652,733
JBrowse link
G Mchr1 melanin-concentrating hormone receptor 1 increases expression ISO manganese chloride results in increased expression of MCHR1 mRNA CTD PMID:17175027 NCBI chr 7:112,761,554...112,764,746
Ensembl chr 7:112,761,554...112,764,032
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression EXP manganese chloride results in decreased expression of MCL1 protein CTD PMID:27107493 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 decreases expression ISO manganese chloride results in decreased expression of MCM4 mRNA CTD PMID:17175027 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO manganese chloride results in decreased expression of MCM5 mRNA CTD PMID:17175027 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
JBrowse link
G Mcoln3 mucolipin TRP cation channel 3 increases expression EXP manganese chloride results in increased expression of MCOLN3 mRNA CTD PMID:26745496 NCBI chr 2:234,966,010...235,043,047
Ensembl chr 2:234,966,010...235,043,047
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP manganese chloride results in increased expression of MDM2 mRNA CTD PMID:28801915 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Me3 malic enzyme 3 increases expression ISO manganese chloride results in increased expression of ME3 mRNA CTD PMID:17175027 NCBI chr 1:143,534,024...143,735,551
Ensembl chr 1:143,534,139...143,733,132
JBrowse link
G Medag mesenteric estrogen-dependent adipogenesis increases expression EXP manganese chloride results in increased expression of MEDAG mRNA CTD PMID:28801915 NCBI chr12:5,613,191...5,634,701
Ensembl chr12:5,613,208...5,634,767
JBrowse link
G Mef2c myocyte enhancer factor 2C decreases expression
increases methylation
EXP manganese chloride results in decreased expression of MEF2C mRNA
manganese chloride results in increased methylation of MEF2C gene
CTD PMID:28801915 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Mepe matrix extracellular phosphoglycoprotein increases methylation
increases expression
EXP manganese chloride results in increased methylation of MEPE gene
manganese chloride results in increased expression of MEPE mRNA
CTD PMID:28801915 NCBI chr14:5,420,634...5,432,186
Ensembl chr14:5,420,635...5,432,183
JBrowse link
G Metap2 methionyl aminopeptidase 2 multiple interactions
increases activity
ISO manganese chloride inhibits the reaction [Triazoles results in decreased activity of METAP2 protein]
manganese chloride results in increased activity of METAP2 protein
CTD PMID:12718546 NCBI chr 7:28,412,771...28,440,458
Ensembl chr 7:28,411,608...28,440,434
JBrowse link
G Mfap2 microfibril associated protein 2 decreases expression
decreases methylation
EXP manganese chloride results in decreased expression of MFAP2 mRNA
manganese chloride results in decreased methylation of MFAP2 gene
CTD PMID:28801915 NCBI chr 5:153,312,068...153,320,266
Ensembl chr 5:153,314,711...153,320,259
JBrowse link
G Mfn2 mitofusin 2 decreases expression
multiple interactions
ISO manganese chloride results in decreased expression of MFN2 mRNA; manganese chloride results in decreased expression of MFN2 protein
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride results in decreased expression of MFN2 protein]]; Resveratrol inhibits the reaction [manganese chloride results in decreased expression of MFN2 protein]
CTD PMID:28539244 PMID:34738708 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mfsd6 major facilitator superfamily domain containing 6 increases expression EXP manganese chloride results in increased expression of MFSD6 mRNA CTD PMID:28801915 NCBI chr 9:48,773,171...48,858,471
Ensembl chr 9:48,773,414...48,858,465
JBrowse link
G Mga MAX dimerization protein MGA increases expression EXP manganese chloride results in increased expression of MGA mRNA CTD PMID:28801915 NCBI chr 3:106,851,216...106,942,908
Ensembl chr 3:106,851,140...106,941,043
JBrowse link
G Mgat1 alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase increases expression ISO manganese chloride results in increased expression of MGAT1 mRNA CTD PMID:15295902 NCBI chr10:33,563,642...33,582,718
Ensembl chr10:33,561,388...33,591,503
JBrowse link
G Mgat5b alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B increases expression EXP manganese chloride results in increased expression of MGAT5B mRNA CTD PMID:28801915 NCBI chr10:102,120,757...102,190,235
Ensembl chr10:102,120,445...102,190,233
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases methylation
increases expression
ISO
EXP
manganese chloride results in increased methylation of MGMT gene
manganese chloride results in increased expression of MGMT mRNA
CTD PMID:27913844 PMID:28801915 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Mgp matrix Gla protein increases expression EXP manganese chloride results in increased expression of MGP mRNA CTD PMID:28801915 NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 decreases expression EXP manganese chloride results in decreased expression of MGST1 mRNA CTD PMID:28801915 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 increases expression EXP manganese chloride results in increased expression of MGST3 mRNA CTD PMID:28801915 NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411
JBrowse link
G Mia MIA SH3 domain containing increases expression ISO
EXP
manganese chloride results in increased expression of MIA mRNA CTD PMID:17175027 PMID:28801915 NCBI chr 1:82,473,677...82,476,378
Ensembl chr 1:82,473,678...82,475,370
JBrowse link
G Mical1 microtubule associated monooxygenase, calponin and LIM domain containing 1 decreases expression EXP manganese chloride results in decreased expression of MICAL1 mRNA CTD PMID:28801915 NCBI chr20:44,974,137...44,986,089
Ensembl chr20:44,974,138...44,986,089
JBrowse link
G Mir107 microRNA 107 decreases expression ISO manganese chloride results in decreased expression of MIR107 mRNA CTD PMID:28986288 NCBI chr 1:232,337,767...232,337,853
Ensembl chr 1:232,337,767...232,337,853
JBrowse link
G Mir125b1 microRNA 125b-1 multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in increased expression of MIR125B1 mRNA CTD PMID:31555879 NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052
JBrowse link
G Mir134 microRNA 134 increases expression ISO manganese chloride results in increased expression of MIR134 mRNA CTD PMID:28986288 NCBI chr 6:128,748,908...128,748,980 JBrowse link
G Mir139 microRNA 139 decreases expression ISO manganese chloride results in decreased expression of MIR139 mRNA CTD PMID:28986288 NCBI chr 1:155,878,828...155,878,895
Ensembl chr 1:155,878,825...155,878,902
JBrowse link
G Mir146b microRNA 146b decreases expression ISO manganese chloride results in decreased expression of MIR146B mRNA CTD PMID:28986288 NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525
JBrowse link
G Mir298 microRNA 298 decreases expression ISO manganese chloride results in decreased expression of MIR298 mRNA CTD PMID:28986288 NCBI chr 3:163,052,291...163,052,372
Ensembl chr 3:163,052,291...163,052,372
JBrowse link
G Mir29a microRNA 29a decreases expression ISO manganese chloride results in decreased expression of MIR29A mRNA CTD PMID:28986288 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir320a microRNA 320a increases expression ISO manganese chloride results in increased expression of MIR320A mRNA CTD PMID:28986288 NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
JBrowse link
G Mir328 microRNA 328 decreases expression ISO manganese chloride results in decreased expression of MIR328 mRNA CTD PMID:28986288 NCBI chr19:33,184,766...33,184,849
Ensembl chr19:33,184,766...33,184,849
JBrowse link
G Mir409 microRNA 409 decreases expression ISO manganese chloride results in decreased expression of MIR409 mRNA CTD PMID:28986288 NCBI chr 6:128,757,780...128,757,856
Ensembl chr 6:128,757,779...128,757,858
JBrowse link
G Mir433 microRNA 433 decreases expression ISO manganese chloride results in decreased expression of MIR433 mRNA CTD PMID:28986288 NCBI chr 6:128,545,119...128,545,211
Ensembl chr 6:128,545,112...128,545,217
JBrowse link
G Mir582 microRNA 582 multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in decreased expression of MIR582 mRNA CTD PMID:31555879 NCBI chr 2:40,928,571...40,928,651
Ensembl chr 2:40,928,571...40,928,651
JBrowse link
G Mir98 microRNA 98 decreases expression ISO manganese chloride results in decreased expression of MIR98 mRNA CTD PMID:28986288 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342
JBrowse link
G Mirlet7b microRNA let-7b increases expression ISO manganese chloride results in increased expression of MIRLET7B mRNA CTD PMID:28986288 NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:116,804,186...116,804,270
JBrowse link
G Mmab metabolism of cobalamin associated B decreases expression EXP manganese chloride results in decreased expression of MMAB mRNA CTD PMID:28801915 NCBI chr12:42,159,109...42,172,496
Ensembl chr12:42,159,089...42,172,490
JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression EXP manganese chloride results in increased expression of MMP13 mRNA CTD PMID:26745496 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Mmp14 matrix metallopeptidase 14 decreases expression
increases methylation
EXP manganese chloride results in decreased expression of MMP14 mRNA
manganese chloride results in increased methylation of MMP14 gene
CTD PMID:28801915 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Mmp24 matrix metallopeptidase 24 increases expression EXP manganese chloride results in increased expression of MMP24 mRNA CTD PMID:28801915 NCBI chr 3:144,279,096...144,323,572
Ensembl chr 3:144,279,096...144,323,572
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression EXP manganese chloride results in increased expression of MMP3 mRNA CTD PMID:26745496 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased expression of and results in increased secretion of MMP9 protein]; manganese chloride results in increased expression of and results in increased secretion of MMP9 protein; resveratrol inhibits the reaction [manganese chloride results in increased expression of and results in increased secretion of MMP9 protein]; resveratrol inhibits the reaction [manganese chloride results in increased expression of MMP9 mRNA] CTD PMID:23811825 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mnda myeloid cell nuclear differentiation antigen decreases expression EXP manganese chloride results in decreased expression of IFI204 mRNA CTD PMID:28801915 NCBI chr13:86,017,888...86,035,556
Ensembl chr13:86,017,892...86,034,201
JBrowse link
G Mob3b MOB kinase activator 3B increases expression EXP manganese chloride results in increased expression of MOB3B mRNA CTD PMID:28801915 NCBI chr 5:49,541,804...49,737,934
Ensembl chr 5:49,545,815...49,737,934
JBrowse link
G Mon2 MON2 homolog, regulator of endosome-to-Golgi trafficking decreases expression EXP manganese chloride results in decreased expression of MON2 mRNA CTD PMID:28801915 NCBI chr 7:58,649,378...58,728,102
Ensembl chr 7:58,651,075...58,728,064
JBrowse link
G Mpc1l mitochondrial pyruvate carrier 1-like increases expression EXP manganese chloride results in increased expression of MPC1L mRNA CTD PMID:28801915 NCBI chr  X:10,146,274...10,147,145
Ensembl chr  X:10,146,293...10,147,145
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
ISO
EXP
diphenyleneiodonium inhibits the reaction [manganese chloride promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased activity of MPO protein]]; manganese chloride promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased activity of MPO protein]; manganese chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; Sodium Azide inhibits the reaction [manganese chloride promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased activity of MPO protein]]
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased activity of MPO protein]; [manganese chloride results in increased abundance of Manganese] which results in increased activity of MPO protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased activity of MPO protein]; Quercetin inhibits the reaction [manganese chloride results in increased activity of MPO protein]
CTD PMID:22906169 PMID:28040552 PMID:30844427 PMID:33314588 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mpp3 MAGUK p55 scaffold protein 3 increases expression EXP manganese chloride results in increased expression of MPP3 mRNA CTD PMID:28801915 NCBI chr10:86,945,705...86,975,261
Ensembl chr10:86,945,714...86,974,737
JBrowse link
G Mrps10 mitochondrial ribosomal protein S10 decreases expression EXP manganese chloride results in decreased expression of MRPS10 mRNA CTD PMID:28801915 NCBI chr 9:13,614,897...13,624,819
Ensembl chr 9:13,614,897...13,624,779
JBrowse link
G Ms4a6a membrane spanning 4-domains A6A increases expression EXP manganese chloride results in increased expression of MS4A6A mRNA CTD PMID:28801915 NCBI chr 1:208,401,465...208,414,831
Ensembl chr 1:208,401,466...208,414,758
JBrowse link
G Msh5 mutS homolog 5 increases expression EXP manganese chloride results in increased expression of MSH5 mRNA CTD PMID:28801915 NCBI chr20:3,773,867...3,793,337
Ensembl chr20:3,776,942...3,793,336
JBrowse link
G Msh6 mutS homolog 6 decreases expression ISO manganese chloride results in decreased expression of MSH6 mRNA CTD PMID:17175027 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
JBrowse link
G Msx2 msh homeobox 2 decreases expression EXP manganese chloride results in decreased expression of MSX2 mRNA CTD PMID:28801915 NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879
JBrowse link
G Mt1 metallothionein 1 decreases expression EXP manganese chloride results in decreased expression of MT1A mRNA CTD PMID:12387356 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
JBrowse link
G Mt3 metallothionein 3 increases expression EXP manganese chloride results in increased expression of MT3 mRNA CTD PMID:28801915 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
JBrowse link
G Mta1 metastasis associated 1 increases expression EXP manganese chloride results in increased expression of MTA1 mRNA CTD PMID:28801915 NCBI chr 6:132,178,608...132,217,641
Ensembl chr 6:132,178,853...132,217,641
JBrowse link
G Mtap methylthioadenosine phosphorylase increases expression EXP manganese chloride results in increased expression of MTAP mRNA CTD PMID:28801915 NCBI chr 5:103,873,020...103,939,406
Ensembl chr 5:103,873,020...103,939,406
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase increases expression
increases methylation
EXP manganese chloride results in increased expression of MTHFD2 mRNA
manganese chloride results in increased methylation of MTHFD2 gene
CTD PMID:28801915 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like increases expression EXP manganese chloride results in increased expression of MTHFD2L mRNA CTD PMID:28801915