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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:IWR-1-exo
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Accession:CHEBI:62883 term browser browse the term
Definition:A dicarboximide having an exo bridged phthalimide structure, substituted at nitrogen by a 4-(quinolin-8-ylcarbamoyl)benzoyl group. It is a weak axin stabilizer, an analogue of IWR-1-endo.
Synonyms:exact_synonym: 4-[(3aR,4R,7S,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl]-N-(quinolin-8-yl)benzamide
 related_synonym: Formula=C25H19N3O3;   InChI=1S/C25H19N3O3/c29-23(27-19-5-1-3-14-4-2-12-26-22(14)19)15-8-10-18(11-9-15)28-24(30)20-16-6-7-17(13-16)21(20)25(28)31/h1-12,16-17,20-21H,13H2,(H,27,29)/t16-,17+,20+,21-;   InChIKey=ZGSXEXBYLJIOGF-BTYSMDAFSA-N;   SMILES=[H][C@@]12[C@@H]3C[C@@H](C=C3)[C@]1([H])C(=O)N(C2=O)c1ccc(cc1)C(=O)Nc1cccc2cccnc12
 xref: PMID:19125156;   PMID:19410457;   PMID:19759537;   Patent:WO2009155001;   Reaxys:19908762


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Path 1
Term Annotations click to browse term
  CHEBI ontology 19840
    role 19790
      biological role 19790
        biochemical role 19328
          axin stabilizer 0
            IWR-1-exo 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19840
    subatomic particle 19838
      composite particle 19838
        hadron 19838
          baryon 19838
            nucleon 19838
              atomic nucleus 19838
                atom 19838
                  main group element atom 19730
                    p-block element atom 19730
                      p-block molecular entity 19730
                        pnictogen molecular entity 18717
                          nitrogen molecular entity 18612
                            amide 17451
                              secondary amide 6068
                                imide 6067
                                  dicarboximide 6036
                                    IWR-1-exo 0
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