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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:odorant receptor agonist
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Accession:CHEBI:62873 term browser browse the term
Definition:An agonist that selectively binds to and activates an odorant receptor.


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benzaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b8 aldo-keto reductase family 1, member B8 multiple interactions EXP [AKR1B8 protein co-treated with NADP] affects the reduction of benzaldehyde CTD PMID:18845131 NCBI chr 4:61,772,064...61,784,637
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases oxidation
increases metabolic processing
EXP
ISO
ALDH1A1 protein results in increased oxidation of benzaldehyde
ALDH1A1 protein results in increased metabolism of benzaldehyde
CTD PMID:10998257 PMID:21256123 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member increases metabolic processing
multiple interactions
ISO ALDH2 protein results in increased metabolism of benzaldehyde
benzaldehyde inhibits the reaction [4-dimethylaminocinnamaldehyde binds to ALDH2 protein]
CTD PMID:10609638 PMID:11744614 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 multiple interactions
increases oxidation
increases metabolic processing
ISO [ALDH3A1 protein co-treated with NAD] results in increased oxidation of benzaldehyde; [ALDH3A1 protein co-treated with NADP] results in increased oxidation of benzaldehyde; Cimetidine inhibits the reaction [ALDH3A1 protein results in increased oxidation of benzaldehyde]
ALDH3A1 protein results in increased metabolism of benzaldehyde
CTD PMID:10856427 PMID:21256123 PMID:21349255 PMID:23220590 PMID:25512087 NCBI chr10:47,490,168...47,499,855
Ensembl chr10:47,490,153...47,499,876
JBrowse link
G Aldh3b1 aldehyde dehydrogenase 3 family, member B1 affects binding ISO benzaldehyde binds to ALDH3B1 protein CTD PMID:20699116 NCBI chr 1:219,145,457...219,181,536
Ensembl chr 1:219,145,459...219,186,860
JBrowse link
G Ar androgen receptor multiple interactions EXP benzaldehyde inhibits the reaction [Metribolone binds to AR protein] CTD PMID:3695475 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases activity
multiple interactions
ISO benzaldehyde results in increased activity of SLC2A1 protein
[benzaldehyde co-treated with Glucose deficiency] results in decreased activity of SLC2A1 protein
CTD PMID:20955755 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19817
    role 19767
      biological role 19767
        pharmacological role 18836
          agonist 18231
            odorant receptor agonist 7
              benzaldehyde 7
              traseolide + 0
paths to the root