Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:4-hydroxy-17beta-estradiol
go back to main search page
Accession:CHEBI:62845 term browser browse the term
Definition:A 4-hydroxy steroid that consists of 17beta-estradiol having an additional hydroxy group at position 4.
Synonyms:exact_synonym: estra-1,3,5(10)-triene-3,14,17beta-triol
 related_synonym: 3,4,17beta-estriol;   3,4,17beta-trihydroxy-1,3,5[10]-estratriene;   4-Hydroxyestradiol-17beta;   4-OH-Estradiol;   4-hydroxyestradiol;   4OHE2;   Formula=C18H24O3;   InChI=1S/C18H24O3/c1-18-9-8-11-10-4-6-15(19)17(21)13(10)3-2-12(11)14(18)5-7-16(18)20/h4,6,11-12,14,16,19-21H,2-3,5,7-9H2,1H3/t11-,12-,14+,16+,18+/m1/s1;   InChIKey=QOZFCKXEVSGWGS-ZHIYBZGJSA-N;   SMILES=[H][C@]12CC[C@]3(C)[C@@H](O)CC[C@@]3([H])[C@]1([H])CCc1c(O)c(O)ccc21
 alt_id: CHEBI:34424
 xref: CAS:5976-61-4 "ChemIDplus";   HMDB:HMDB0005896;   KEGG:C14209;   LIPID_MAPS_instance:LMST02010028 "LIPID MAPS"
 xref_mesh: MESH:C014036
 xref: PMID:10077490 "Europe PMC";   PMID:11258977 "Europe PMC";   PMID:11812141 "Europe PMC";   PMID:11961123 "Europe PMC";   PMID:12093619 "Europe PMC";   PMID:12493568 "Europe PMC";   PMID:16112522 "Europe PMC";   PMID:17173372 "Europe PMC";   PMID:18379081 "Europe PMC";   PMID:20540524 "Europe PMC";   PMID:20708024 "Europe PMC";   PMID:9554872 "Europe PMC";   Reaxys:2219366 "Reaxys"


show annotations for term's descendants       view all columns           Sort by:
 
4-hydroxy-17beta-estradiol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Alpg alkaline phosphatase, germ cell JBrowse link 9 94,164,667 94,184,972 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Comt catechol-O-methyltransferase JBrowse link 11 86,715,981 86,735,630 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:6480464
G Foxo1 forkhead box O1 JBrowse link 2 141,451,234 141,527,016 RGD:6480464
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:6480464
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:6480464
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:6480464
G Ltf lactotransferrin JBrowse link 8 119,290,416 119,313,261 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mt-atp6 mitochondrially encoded ATP synthase 6 JBrowse link MT 7,919 8,599 RGD:6480464
G Mt-co3 mitochondrially encoded cytochrome c oxidase III JBrowse link MT 8,599 9,382 RGD:6480464
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:6480464
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Shbg sex hormone binding globulin JBrowse link 10 56,219,861 56,237,354 RGD:6480464
G Sphk1 sphingosine kinase 1 JBrowse link 10 105,498,728 105,504,401 RGD:6480464
G Tff1 trefoil factor 1 JBrowse link 20 9,892,124 9,895,984 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        biochemical role 19138
          metabolite 19106
            4-hydroxy-17beta-estradiol 27
              4-hydroxy-17beta-estradiol 3-O-(beta-D-glucuronide) 0
              4-hydroxy-17beta-estradiol 4-O-(beta-D-glucuronide) 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic molecule 19343
                              organic cyclic compound 19093
                                organic polycyclic compound 16028
                                  steroid 12767
                                    steroid fundamental parent 12390
                                      estrane 9634
                                        estradiol 9476
                                          17beta-estradiol 9476
                                            4-hydroxy-17beta-estradiol 27
                                              4-hydroxy-17beta-estradiol 3-O-(beta-D-glucuronide) 0
                                              4-hydroxy-17beta-estradiol 4-O-(beta-D-glucuronide) 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.