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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-nitrobenzyl bromide
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Accession:CHEBI:62822 term browser browse the term
Definition:A C-nitro compound that consists of nitrobenzene bearing a bromomethyl substituent at the para-position.
Synonyms:exact_synonym: 1-(bromomethyl)-4-nitrobenzene
 related_synonym: 4-(Bromomethyl)nitrobenzene;   Formula=C7H6BrNO2;   InChI=1S/C7H6BrNO2/c8-5-6-1-3-7(4-2-6)9(10)11/h1-4H,5H2;   InChIKey=VOLRSQPSJGXRNJ-UHFFFAOYSA-N;   Nitrobenzyl bromide;   SMILES=[O-][N+](=O)c1ccc(CBr)cc1;   alpha-Bromo-4-nitrotoluene;   alpha-Bromo-p-nitrotoluene;   alpha-Bromoparanitrotoluene;   p-(Bromomethyl)nitrobenzene;   p-Nitrobenzyl bromide
 xref: CAS:100-11-8
 xref_mesh: MESH:C027563
 xref: PMID:14505719;   PMID:19739607;   PMID:19928804;   PMID:20092329;   PMID:20940038;   PMID:2282796;   PMID:29079364;   PMID:6530466;   PMID:7190617;   PMID:9565311;   Patent:WO2010052536;   Reaxys:742796



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4-nitrobenzyl bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c2 aldo-keto reductase family 1, member C2 increases activity
increases expression
ISO 4-nitrobenzyl bromide results in increased activity of AKR1C2 promoter
4-nitrobenzyl bromide results in increased expression of AKR1C2 mRNA
CTD PMID:21195160 PMID:25724174 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO 4-nitrobenzyl bromide results in increased expression of ATF3 mRNA CTD PMID:23999411 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO 4-nitrobenzyl bromide results in increased expression of DNAJB4 mRNA CTD PMID:23999411 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO 4-nitrobenzyl bromide results in increased expression of GCLM mRNA CTD PMID:23999411 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO 4-nitrobenzyl bromide results in increased expression of HMOX1 mRNA CTD PMID:23445166 PMID:25724174 PMID:26244607 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 increases expression ISO 4-nitrobenzyl bromide results in increased expression of HSPA6 mRNA CTD PMID:23999411 NCBI chr13:83,271,340...83,275,267 JBrowse link
G Il18 interleukin 18 increases expression ISO 4-nitrobenzyl bromide results in increased expression of IL18 protein CTD PMID:23063874 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO 4-nitrobenzyl bromide results in increased expression of IL1A mRNA CTD PMID:33715048 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta increases secretion
increases expression
ISO 4-nitrobenzyl bromide results in increased secretion of IL1B protein
4-nitrobenzyl bromide results in increased expression of IL1B mRNA
CTD PMID:33715048 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO 4-nitrobenzyl bromide results in increased expression of NQO1 mRNA CTD PMID:25724174 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19715
    role 19690
      biological role 19688
        aetiopathogenetic role 19040
          sensitiser 9838
            4-nitrobenzyl bromide 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19715
    subatomic particle 19713
      composite particle 19713
        hadron 19713
          baryon 19713
            nucleon 19713
              atomic nucleus 19713
                atom 19713
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19606
                        carbon atom 19603
                          organic molecular entity 19603
                            heteroorganic entity 19347
                              organohalogen compound 18227
                                organobromine compound 6565
                                  benzyl bromides 14
                                    4-nitrobenzyl bromide 10
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