CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 4-nitrobenzyl bromide
Accession: CHEBI:62822
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Definition: A C-nitro compound that consists of nitrobenzene bearing a bromomethyl substituent at the para-position.
Synonyms: exact_synonym: 1-(bromomethyl)-4-nitrobenzene
related_synonym: 4-(Bromomethyl)nitrobenzene; Formula=C7H6BrNO2; InChI=1S/C7H6BrNO2/c8-5-6-1-3-7(4-2-6)9(10)11/h1-4H,5H2; InChIKey=VOLRSQPSJGXRNJ-UHFFFAOYSA-N; Nitrobenzyl bromide; SMILES=[O-][N+](=O)c1ccc(CBr)cc1; alpha-Bromo-4-nitrotoluene; alpha-Bromo-p-nitrotoluene; alpha-Bromoparanitrotoluene; p-(Bromomethyl)nitrobenzene; p-Nitrobenzyl bromide
xref: CAS:100-11-8
xref_mesh: MESH:C027563
xref: PMID:14505719; PMID:19739607; PMID:19928804; PMID:20092329; PMID:20940038; PMID:2282796; PMID:29079364; PMID:6530466; PMID:7190617; PMID:9565311; Patent:WO2010052536; Reaxys:742796
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Akr1c2
aldo-keto reductase family 1, member C2
increases activity increases expression
ISO
4-nitrobenzyl bromide results in increased activity of AKR1C2 promoter 4-nitrobenzyl bromide results in increased expression of AKR1C2 mRNA
CTD
PMID:21195160 PMID:25724174
NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
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Atf3
activating transcription factor 3
increases expression
ISO
4-nitrobenzyl bromide results in increased expression of ATF3 mRNA
CTD
PMID:23999411
NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
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Dnajb4
DnaJ heat shock protein family (Hsp40) member B4
increases expression
ISO
4-nitrobenzyl bromide results in increased expression of DNAJB4 mRNA
CTD
PMID:23999411
NCBI chr 2:257,394,692...257,425,344
Ensembl chr 2:257,394,818...257,425,242
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Gclm
glutamate cysteine ligase, modifier subunit
increases expression
ISO
4-nitrobenzyl bromide results in increased expression of GCLM mRNA
CTD
PMID:23999411
NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
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Hmox1
heme oxygenase 1
increases expression
ISO
4-nitrobenzyl bromide results in increased expression of HMOX1 mRNA
CTD
PMID:23445166 PMID:25724174 PMID:26244607
NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
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Il18
interleukin 18
increases expression
ISO
4-nitrobenzyl bromide results in increased expression of IL18 protein
CTD
PMID:23063874
NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
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LOC686035
similar to heat shock 70kDa protein 6 (HSP70B)
increases expression
ISO
4-nitrobenzyl bromide results in increased expression of HSPA6 mRNA
CTD
PMID:23999411
NCBI chr13:89,408,703...89,411,500
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
ISO
4-nitrobenzyl bromide results in increased expression of NQO1 mRNA
CTD
PMID:25724174
NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
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