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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:allelochemical
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Accession:CHEBI:62215 term browser browse the term
Definition:A class of secondary metabolites developed by many plants to influence the behaviour, growth or survival of herbivores, and thus acting as a defence against herbivory.
Synonyms:related_synonym: allelochemicals


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2-benzoxazolinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO benzoxazolone results in decreased activity of CYP1A2 protein CTD PMID:15916432 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
4-hydroxyestrone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfe2l2 nuclear factor, erythroid 2-like 2 decreases expression
decreases response to substance
ISO 4-hydroxyestrone results in decreased expression of NFE2L2 mRNA
NFE2L2 protein results in decreased susceptibility to 4-hydroxyestrone
CTD PMID:25231996 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of 4-hydroxyestrone CTD PMID:15117964 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of 4-hydroxyestrone CTD PMID:15117964 NCBI chr 9:88,791,216...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of 4-hydroxyestrone CTD PMID:15117964 NCBI chr 9:88,696,981...88,808,465 JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 increases glucuronidation ISO UGT2B7 protein alternative form results in increased glucuronidation of 4-hydroxyestrone; UGT2B7 protein results in increased glucuronidation of 4-hydroxyestrone CTD PMID:8423545 PMID:8517101 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
JBrowse link
aspalathin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO aspalathin inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; aspalathin inhibits the reaction [Glucose results in increased expression of CCL2 protein] CTD PMID:25338943 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G F10 coagulation factor X multiple interactions ISO aspalathin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein]; aspalathin inhibits the reaction [[TNF protein co-treated with F7 protein] results in increased expression of F10 protein] CTD PMID:25325928 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
JBrowse link
G F2 coagulation factor II multiple interactions ISO aspalathin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein] CTD PMID:25325928 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F5 coagulation factor V multiple interactions ISO aspalathin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein] CTD PMID:25325928 NCBI chr13:76,513,463...76,583,106
Ensembl chr13:76,513,255...76,582,317
JBrowse link
G F7 coagulation factor VII multiple interactions ISO aspalathin inhibits the reaction [[TNF protein co-treated with F7 protein] results in increased expression of F10 protein] CTD PMID:25325928 NCBI chr16:76,489,779...76,500,636
Ensembl chr16:76,489,717...76,500,610
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO aspalathin inhibits the reaction [Glucose results in increased expression of ICAM1 protein]; aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ICAM1 mRNA]; aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ICAM1 protein] CTD PMID:25338943 PMID:25655391 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il6 interleukin 6 multiple interactions ISO aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein] CTD PMID:25655391 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein] CTD PMID:25655391 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein] CTD PMID:25655391 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA] CTD PMID:25655391 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO aspalathin inhibits the reaction [Glucose affects the localization of RELA protein]; aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of RELA protein] CTD PMID:25338943 PMID:25655391 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Sele selectin E multiple interactions ISO aspalathin inhibits the reaction [Glucose results in increased expression of SELE protein]; aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE mRNA]; aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE protein] CTD PMID:25338943 PMID:25655391 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO aspalathin inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein] CTD PMID:25325928 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein] CTD PMID:25655391 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO aspalathin inhibits the reaction [[TNF protein co-treated with F7 protein] results in increased expression of F10 protein]; aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]; aspalathin inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein] CTD PMID:25325928 PMID:25655391 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO aspalathin inhibits the reaction [Glucose results in increased expression of VCAM1 protein]; aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of VCAM1 mRNA]; aspalathin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of VCAM1 protein] CTD PMID:25338943 PMID:25655391 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
catechol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO AHR gene mutant form inhibits the reaction [catechol results in decreased expression of MYB protein] CTD PMID:15935814 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 increases expression
multiple interactions
ISO catechol results in increased expression of ALAS2 mRNA
[catechol co-treated with Hemin] results in increased expression of ALAS2 mRNA; catechol inhibits the reaction [[S-Adenosylhomocysteine co-treated with Hemin] results in increased expression of ALAS2 mRNA]; catechol inhibits the reaction [[S-Adenosylmethionine co-treated with Hemin] results in increased expression of ALAS2 mRNA]; catechol promotes the reaction [Hemin results in increased expression of ALAS2 mRNA]; COMT mutant form inhibits the reaction [[catechol co-treated with Hemin] results in increased expression of ALAS2 mRNA]; Hemin promotes the reaction [catechol results in increased expression of ALAS2 mRNA]
CTD PMID:23022512 PMID:24141029 PMID:28552822 NCBI chr  X:19,463,146...19,486,526
Ensembl chr  X:19,463,171...19,486,519
JBrowse link
G Aurkb aurora kinase B increases expression EXP catechol results in increased expression of AURKB protein CTD PMID:23535288 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO Catechin inhibits the reaction [catechol results in increased activity of CASP3 protein]; Memantine inhibits the reaction [catechol results in increased activity of CASP3 protein] CTD PMID:20347921 PMID:23776099 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 increases activity
multiple interactions
ISO catechol results in increased activity of CASP7 protein
Catechin inhibits the reaction [catechol results in increased activity of CASP7 protein]; Memantine inhibits the reaction [catechol results in increased activity of CASP7 protein]
CTD PMID:20347921 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 increases activity ISO catechol results in increased activity of CASP8 protein CTD PMID:23776099 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity ISO catechol results in increased activity of CASP9 protein CTD PMID:23776099 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression ISO catechol results in increased expression of CCL11 protein CTD PMID:17572062 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO catechol results in increased expression of CCL2 protein CTD PMID:17572062 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO catechol results in increased expression of CCL3 protein CTD PMID:17572062 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO catechol results in increased expression of CCL4 protein CTD PMID:17572062 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO catechol results in increased expression of CCL5 protein CTD PMID:17572062 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression
increases expression
EXP catechol results in decreased expression of CDK1 protein
catechol results in increased expression of CDK1 protein
CTD PMID:23535288 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP catechol results in increased expression of CDKN1A protein CTD PMID:23535288 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Chek1 checkpoint kinase 1 increases expression ISO catechol results in increased expression of CHEK1 protein CTD PMID:20025956 NCBI chr 8:36,420,565...36,443,477 JBrowse link
G Comt catechol-O-methyltransferase increases methylation
increases response to substance
multiple interactions
ISO
EXP
COMT protein results in increased methylation of catechol
COMT mutant form results in increased susceptibility to catechol
COMT mutant form inhibits the reaction [[catechol co-treated with Hemin] results in increased expression of ALAS2 mRNA]; COMT mutant form inhibits the reaction [[catechol co-treated with Hemin] results in increased expression of HBB mRNA]; COMT mutant form inhibits the reaction [[catechol co-treated with Hemin] results in increased expression of HMBS mRNA]; COMT mutant form inhibits the reaction [catechol results in increased abundance of Guaiacol]
CTD PMID:11160877 PMID:24141029 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP
ISO
[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of catechol; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of catechol]
[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of catechol
CTD PMID:8211999 PMID:15051535 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions EXP EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of catechol] CTD PMID:8211999 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO catechol results in increased expression of FAS protein CTD PMID:23776099 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand increases expression ISO catechol results in increased expression of FASLG protein CTD PMID:23776099 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO catechol results in increased expression of FOSL1 protein CTD PMID:20025956 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Gata1 GATA binding protein 1 increases expression
multiple interactions
ISO catechol results in increased expression of GATA1 mRNA
catechol promotes the reaction [Hemin results in increased expression of GATA1 mRNA]; Hemin promotes the reaction [catechol results in increased expression of GATA1 mRNA]
CTD PMID:23022512 PMID:28552822 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530
JBrowse link
G Hbb hemoglobin subunit beta increases expression
multiple interactions
decreases methylation
ISO catechol results in increased expression of HBB mRNA
[catechol co-treated with Hemin] results in increased expression of HBB mRNA; catechol inhibits the reaction [[S-Adenosylhomocysteine co-treated with Hemin] results in increased expression of HBB mRNA]; catechol inhibits the reaction [[S-Adenosylmethionine co-treated with Hemin] results in increased expression of HBB mRNA]; catechol promotes the reaction [Hemin results in increased expression of HBB mRNA]; COMT mutant form inhibits the reaction [[catechol co-treated with Hemin] results in increased expression of HBB mRNA]; Hemin promotes the reaction [catechol results in increased expression of HBB mRNA]
catechol results in decreased methylation of HBB promoter
CTD PMID:23022512 PMID:24141029 PMID:28552822 NCBI chr 1:158,250,421...158,251,832 JBrowse link
G Hmbs hydroxymethylbilane synthase increases expression
increases methylation
multiple interactions
decreases methylation
ISO catechol results in increased expression of HMBS mRNA
catechol results in increased methylation of HMBS exon
[catechol co-treated with Hemin] results in increased expression of HMBS mRNA; catechol inhibits the reaction [[S-Adenosylhomocysteine co-treated with Hemin] results in increased expression of HMBS mRNA]; catechol inhibits the reaction [[S-Adenosylmethionine co-treated with Hemin] results in increased expression of HMBS mRNA]; catechol promotes the reaction [Hemin results in increased expression of HMBS mRNA]; COMT mutant form inhibits the reaction [[catechol co-treated with Hemin] results in increased expression of HMBS mRNA]; Hemin promotes the reaction [catechol results in increased expression of HMBS mRNA]
catechol results in decreased methylation of HMBS promoter
CTD PMID:23022512 PMID:24141029 PMID:28552822 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957
JBrowse link
G Ifng interferon gamma multiple interactions ISO catechol inhibits the reaction [Amino Acids, Peptides, and Proteins results in increased expression of IFNG protein] CTD PMID:3137358 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il10 interleukin 10 multiple interactions ISO catechol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein] CTD PMID:17572062 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Mir129-1 microRNA 129-1 decreases expression ISO catechol results in decreased expression of MIR129-1 mRNA CTD PMID:32105654 NCBI chr 4:57,624,295...57,624,366
Ensembl chr 4:57,624,295...57,624,366
JBrowse link
G Mir130a microRNA 130a increases expression ISO catechol results in increased expression of MIR130A mRNA CTD PMID:32105654 NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629
JBrowse link
G Mir132 microRNA 132 decreases expression ISO catechol results in decreased expression of MIR132 mRNA CTD PMID:32105654 NCBI chr10:60,023,696...60,023,796
Ensembl chr10:60,023,696...60,023,796
JBrowse link
G Mir134 microRNA 134 decreases expression ISO catechol results in decreased expression of MIR134 mRNA CTD PMID:32105654 NCBI chr 6:128,748,908...128,748,980 JBrowse link
G Mir144 microRNA 144 decreases expression ISO catechol results in decreased expression of MIR144 mRNA CTD PMID:32105654 NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430
JBrowse link
G Mir146a microRNA 146a decreases expression ISO catechol results in decreased expression of MIR146A mRNA CTD PMID:32105654 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
JBrowse link
G Mir16 microRNA 16 decreases expression ISO catechol results in decreased expression of MIR16-2 mRNA CTD PMID:32105654 NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443
JBrowse link
G Mir196b microRNA 196b decreases expression ISO catechol results in decreased expression of MIR196B mRNA CTD PMID:32105654 NCBI chr 4:81,330,487...81,330,571 JBrowse link
G Mir196c microRNA 196c decreases expression ISO catechol results in decreased expression of MIR196A-1 mRNA CTD PMID:32105654 NCBI chr10:81,231,006...81,231,085
Ensembl chr10:81,231,006...81,231,085
JBrowse link
G Mir200c microRNA 200c increases expression ISO catechol results in increased expression of MIR200C mRNA CTD PMID:32105654 NCBI chr 4:157,523,679...157,523,747 JBrowse link
G Mir212 microRNA 212 increases expression ISO catechol results in increased expression of MIR212 mRNA CTD PMID:32105654 NCBI chr10:60,023,403...60,023,513
Ensembl chr10:60,023,403...60,023,513
JBrowse link
G Mir23a microRNA 23a increases expression ISO catechol results in increased expression of MIR23A mRNA CTD PMID:32105654 NCBI chr19:23,954,997...23,955,071
Ensembl chr19:23,954,997...23,955,071
JBrowse link
G Mir29a microRNA 29a increases expression ISO catechol results in increased expression of MIR29A mRNA CTD PMID:32105654 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir31 microRNA 31 increases expression ISO catechol results in increased expression of MIR31 mRNA CTD PMID:32105654 NCBI chr 5:103,599,038...103,599,143 JBrowse link
G Mir324 microRNA 324 decreases expression ISO catechol results in decreased expression of MIR324 mRNA CTD PMID:32105654 NCBI chr10:54,734,680...54,734,762
Ensembl chr10:54,734,678...54,734,766
JBrowse link
G Mir331 microRNA 331 increases expression ISO catechol results in increased expression of MIR331 mRNA CTD PMID:32105654 NCBI chr 7:28,527,390...28,527,485
Ensembl chr 7:28,527,390...28,527,485
JBrowse link
G Mir342 microRNA 342 increases expression ISO catechol results in increased expression of MIR342 mRNA CTD PMID:32105654 NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367
JBrowse link
G Mir410 microRNA 410 increases expression ISO catechol results in increased expression of MIR410 mRNA CTD PMID:32105654 NCBI chr 6:128,758,358...128,758,433
Ensembl chr 6:128,758,354...128,758,434
JBrowse link
G Mir494 microRNA 494 increases expression ISO catechol results in increased expression of MIR494 mRNA CTD PMID:32105654 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
JBrowse link
G Mir496 microRNA 496 decreases expression ISO catechol results in decreased expression of MIR496A mRNA CTD PMID:32105654 NCBI chr 6:128,753,644...128,753,722
Ensembl chr 6:128,753,644...128,753,722
JBrowse link
G Mir598 microRNA 598 increases expression ISO catechol results in increased expression of MIR598 mRNA CTD PMID:32105654 NCBI chr15:37,962,692...37,962,770 JBrowse link
G Mir652 microRNA 652 decreases expression ISO catechol results in decreased expression of MIR652 mRNA CTD PMID:32105654 NCBI chr  X:106,343,293...106,343,373
Ensembl chr  X:106,343,293...106,343,373
JBrowse link
G Mir676 microRNA 676 decreases expression ISO catechol results in decreased expression of MIR676 mRNA CTD PMID:32105654 NCBI chr  X:65,464,494...65,464,582
Ensembl chr  X:65,464,494...65,464,582
JBrowse link
G Mir877 microRNA 877 increases expression ISO catechol results in increased expression of MIR877 mRNA CTD PMID:32105654 NCBI chr20:2,811,476...2,811,560
Ensembl chr20:2,811,476...2,811,560
JBrowse link
G Mir99a microRNA 99a increases expression ISO catechol results in increased expression of MIR99A mRNA CTD PMID:32105654 NCBI chr11:16,200,443...16,200,523
Ensembl chr11:16,200,443...16,200,523
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression
increases expression
EXP catechol results in decreased expression of MKI67 protein
catechol results in increased expression of MKI67 protein
CTD PMID:23535288 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression ISO catechol results in increased expression of MMP12 mRNA CTD PMID:10216232 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
G Myb MYB proto-oncogene, transcription factor multiple interactions
decreases expression
ISO AHR gene mutant form inhibits the reaction [catechol results in decreased expression of MYB protein] CTD PMID:15935814 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO catechol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MYC protein] CTD PMID:12749906 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Neu3 neuraminidase 3 increases expression ISO catechol results in increased expression of NEU3 mRNA CTD PMID:23776099 NCBI chr 1:154,137,732...154,148,879
Ensembl chr 1:154,050,855...154,148,813
JBrowse link
G Nfe2 nuclear factor, erythroid 2 increases expression
multiple interactions
ISO catechol results in increased expression of NFE2 mRNA
catechol promotes the reaction [Hemin results in increased expression of NFE2 mRNA]; Hemin promotes the reaction [catechol results in increased expression of NFE2 mRNA]
CTD PMID:28552822 NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO catechol inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:18499097 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO catechol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; catechol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:18499097 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO catechol results in increased expression of NQO1 mRNA CTD PMID:8652659 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO catechol inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:18499097 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases sulfation ISO SULT1A1 protein results in increased sulfation of catechol CTD PMID:17433394 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Sult1c2a sulfotransferase family, cytosolic, 1C, member 2a increases sulfation ISO SULT1C2 protein results in increased sulfation of catechol CTD PMID:17433394 NCBI chr 9:6,873,697...6,904,736
Ensembl chr 9:6,874,249...6,904,734
JBrowse link
G Tfrc transferrin receptor multiple interactions ISO catechol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TFRC protein] CTD PMID:12749906 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO catechol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; catechol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:18499097 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO catechol results in increased expression of VEGFA protein CTD PMID:20025956 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
cucurbitacin B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA] CTD PMID:29250925 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression ISO cucurbitacin B results in decreased expression of ADIPOQ mRNA CTD PMID:24316209 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of BAX mRNA] CTD PMID:29250925 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in increased expression of BCL2 mRNA] CTD PMID:29250925 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Cat catalase multiple interactions ISO cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein] CTD PMID:29250925 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO cucurbitacin B inhibits the reaction [Gefitinib results in increased expression of CCL2 mRNA] CTD PMID:33248157 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO cucurbitacin B results in decreased expression of CCND1 CTD PMID:24316209 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cd36 CD36 molecule decreases expression ISO cucurbitacin B results in decreased expression of CD36 mRNA CTD PMID:24316209 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression
multiple interactions
ISO cucurbitacin B results in decreased expression of CEBPA mRNA
STAT3 protein affects the reaction [cucurbitacin B results in decreased expression of CEBPA mRNA]
CTD PMID:24316209 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta decreases expression ISO cucurbitacin B results in decreased expression of CEBPD CTD PMID:24316209 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA] CTD PMID:29250925 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO cucurbitacin B results in decreased expression of FABP4 mRNA CTD PMID:24316209 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B protein] CTD PMID:29250925 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Klf5 Kruppel-like factor 5 increases expression ISO cucurbitacin B results in increased expression of KLF5 CTD PMID:24316209 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of MMP2 mRNA] CTD PMID:29250925 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
decreases expression
ISO STAT3 protein affects the reaction [cucurbitacin B results in decreased expression of PPARG mRNA] CTD PMID:24316209 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
affects response to substance
ISO [WP1066 results in decreased activity of STAT3 protein] which results in decreased susceptibility to cucurbitacin B; cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of STAT3 protein]; cucurbitacin B results in decreased phosphorylation of and results in decreased activity of STAT3 protein; STAT3 protein affects the reaction [cucurbitacin B results in decreased expression of CEBPA mRNA]; STAT3 protein affects the reaction [cucurbitacin B results in decreased expression of PPARG mRNA]
STAT3 protein affects the susceptibility to cucurbitacin B
CTD PMID:24316209 PMID:29250925 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA] CTD PMID:29250925 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO cucurbitacin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein] CTD PMID:29250925 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
cucurbitacin E term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle decreases expression
multiple interactions
EXP
ISO
cucurbitacin E results in decreased expression of ACTA2 mRNA; cucurbitacin E results in decreased expression of ACTA2 protein
cucurbitacin E inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein]
CTD PMID:27363783 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
affects phosphorylation
ISO Acetylcysteine inhibits the reaction [cucurbitacin E affects the phosphorylation of AKT1 protein] CTD PMID:27106530 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO
EXP
cucurbitacin E results in increased expression of BAX protein CTD PMID:27106530 PMID:27363783 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO
EXP
cucurbitacin E results in decreased expression of BCL2 protein CTD PMID:27106530 PMID:27363783 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO cucurbitacin E results in decreased expression of BCL2L1 protein CTD PMID:27106530 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Becn1 beclin 1 multiple interactions ISO Acetylcysteine inhibits the reaction [cucurbitacin E results in increased expression of and results in increased phosphorylation of BECN1 protein]; cucurbitacin E results in increased expression of and results in increased phosphorylation of BECN1 protein CTD PMID:27106530 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
ISO
EXP
acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [cucurbitacin E results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in increased cleavage of CASP3 protein] CTD PMID:27106530 PMID:27363783 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions
increases cleavage
ISO acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [cucurbitacin E results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in increased cleavage of CASP7 protein] CTD PMID:27106530 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp9 caspase 9 increases cleavage ISO cucurbitacin E results in increased cleavage of CASP9 protein CTD PMID:27106530 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression EXP cucurbitacin E results in decreased expression of COL1A1 mRNA CTD PMID:27363783 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation EXP cucurbitacin E results in decreased phosphorylation of MAPK1 protein CTD PMID:27363783 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation EXP cucurbitacin E results in decreased phosphorylation of MAPK3 protein CTD PMID:27363783 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
decreases phosphorylation
ISO
EXP
Acetylcysteine inhibits the reaction [cucurbitacin E results in decreased phosphorylation of MTOR protein]
cucurbitacin E inhibits the reaction [Thioacetamide results in increased phosphorylation of MTOR protein]
CTD PMID:27106530 PMID:27363783 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO
EXP
acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [cucurbitacin E results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in increased cleavage of PARP1 protein] CTD PMID:27106530 PMID:27363783 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO cucurbitacin E results in increased expression of and results in increased phosphorylation of PTEN protein CTD PMID:27106530 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions
decreases phosphorylation
ISO
EXP
cucurbitacin E inhibits the reaction [Thioacetamide results in increased phosphorylation of RPS6KB1 protein]
cucurbitacin E results in decreased phosphorylation of RPS6KB1 protein
CTD PMID:27363783 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [cucurbitacin E results in increased expression of SQSTM1 protein] CTD PMID:27106530 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions
decreases expression
ISO
EXP
cucurbitacin E inhibits the reaction [Thioacetamide results in increased expression of TIMP1 protein]
cucurbitacin E results in decreased expression of TIMP1 mRNA; cucurbitacin E results in decreased expression of TIMP1 protein
CTD PMID:27363783 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 multiple interactions ISO Acetylcysteine inhibits the reaction [cucurbitacin E results in decreased expression of and results in decreased phosphorylation of ULK1 protein]; cucurbitacin E results in decreased expression of and results in decreased phosphorylation of ULK1 protein CTD PMID:27106530 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966
JBrowse link
cucurbitacin I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO cucurbitacin I inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin] CTD PMID:16904803 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions EXP cucurbitacin I inhibits the reaction [ADIPOQ protein results in increased expression of HMOX1 mRNA] CTD PMID:20052772 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Casp3 caspase 3 increases cleavage ISO cucurbitacin I results in increased cleavage of CASP3 protein CTD PMID:24858077 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 increases cleavage ISO cucurbitacin I results in increased cleavage of CASP7 protein CTD PMID:24858077 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 increases cleavage ISO cucurbitacin I results in increased cleavage of CASP8 protein CTD PMID:24858077 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases cleavage ISO cucurbitacin I results in increased cleavage of CASP9 protein CTD PMID:24858077 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO cucurbitacin I results in decreased expression of CCNA2 protein CTD PMID:24858077 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO cucurbitacin I results in decreased expression of CCNB1 protein CTD PMID:24858077 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO cucurbitacin I results in decreased expression of CCND1 CTD PMID:24316209 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cd36 CD36 molecule decreases expression ISO cucurbitacin I results in decreased expression of CD36 mRNA CTD PMID:24316209 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO cucurbitacin I results in decreased expression of CDC25C protein CTD PMID:24858077 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO cucurbitacin I results in decreased expression of CDK1 protein CTD PMID:24858077 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression ISO cucurbitacin I results in decreased expression of CEBPA mRNA CTD PMID:24316209 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO cucurbitacin I results in decreased expression of FABP4 mRNA CTD PMID:24316209 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP cucurbitacin I inhibits the reaction [ADIPOQ protein results in increased expression of HMOX1 mRNA] CTD PMID:20052772 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO cucurbitacin I inhibits the reaction [glycine-extended gastrin 17 results in increased phosphorylation of and results in increased activity of JAK2 protein] CTD PMID:19153190 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Klf5 Kruppel-like factor 5 increases expression ISO cucurbitacin I results in increased expression of KLF5 CTD PMID:24316209 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
JBrowse link
G Nppa natriuretic peptide A increases expression EXP cucurbitacin I results in increased expression of NPPA mRNA CTD PMID:27836799 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nppb natriuretic peptide B increases expression EXP cucurbitacin I results in increased expression of NPPB mRNA CTD PMID:27836799 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO cucurbitacin I results in increased cleavage of PARP1 protein CTD PMID:24858077 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO cucurbitacin I results in decreased expression of PPARG mRNA CTD PMID:24316209 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
affects response to substance
decreases activity
ISO cucurbitacin I inhibits the reaction [glycine-extended gastrin 17 results in increased phosphorylation of and results in increased activity of STAT3 protein]
[WP1066 results in decreased activity of STAT3 protein] which results in decreased susceptibility to cucurbitacin I
STAT3 protein affects the susceptibility to cucurbitacin I
cucurbitacin I results in decreased activity of STAT3 protein
CTD PMID:19153190 PMID:24316209 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO cucurbitacin I inhibits the reaction [Arsenic results in increased expression of VEGFA protein] CTD PMID:25559853 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
eugenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca6 ATP binding cassette subfamily A member 6 decreases expression ISO Eugenol results in decreased expression of ABCA6 mRNA CTD PMID:17374397 NCBI chr10:95,142,805...95,212,087
Ensembl chr10:95,142,966...95,211,530
JBrowse link
G Ache acetylcholinesterase multiple interactions EXP Eugenol inhibits the reaction [Chlorpyrifos results in decreased expression of ACHE protein] CTD PMID:32096903 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases activity
affects localization
ISO [Eugenol co-treated with acetyleugenol] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; [Eugenol co-treated with acetyleugenol] results in increased activity of AHR protein; Eugenol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein]; Eugenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]
Eugenol results in increased activity of AHR protein
Eugenol affects the localization of AHR protein
CTD PMID:17275817 PMID:22686307 PMID:29191726 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor increases expression ISO Eugenol results in increased expression of AHRR mRNA CTD PMID:22686307 NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression ISO Eugenol results in increased expression of AKR1B1 mRNA CTD PMID:20566472 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Eugenol results in increased expression of AKR1B10 mRNA CTD PMID:20566472 PMID:26198647 PMID:30806763 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Eugenol results in increased expression of AKR1C2 mRNA CTD PMID:26198647 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression ISO Eugenol results in increased expression of AKR1C3 mRNA CTD PMID:20566472 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases expression ISO Eugenol results in increased expression of ALPL mRNA CTD PMID:22083529 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 multiple interactions ISO Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of APAF1 protein] CTD PMID:20434464 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Ar androgen receptor multiple interactions ISO Eugenol binds to and results in decreased activity of AR protein CTD PMID:20226658 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arhgap17 Rho GTPase activating protein 17 decreases expression ISO Eugenol results in decreased expression of ARHGAP17 mRNA CTD PMID:17374397 NCBI chr 1:177,807,579...177,897,027
Ensembl chr 1:177,807,583...177,896,854
JBrowse link
G Arl4c ADP ribosylation factor like GTPase 4C increases expression ISO Eugenol results in increased expression of ARL4C mRNA CTD PMID:17374397 NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Eugenol results in increased expression of ATF3 mRNA CTD PMID:23999411 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G B2m beta-2 microglobulin increases expression ISO Eugenol results in increased expression of B2M mRNA CTD PMID:17936526 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAD mRNA] CTD PMID:20434464 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAX mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAX protein]
Eugenol results in increased expression of BAX mRNA
CTD PMID:20434464 PMID:20537511 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO [Eugenol results in increased activity of sulforaphane] which results in decreased expression of BCL2; [sulforaphane results in increased activity of Eugenol] which results in decreased expression of BCL2
Eugenol inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Croton Oil] results in increased expression of BCL2 mRNA]; Eugenol inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Croton Oil] results in increased expression of BCL2 protein]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2 protein]
Eugenol results in decreased expression of BCL2 mRNA
CTD PMID:20434464 PMID:20537511 PMID:21382956 PMID:21939359 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2L1 mRNA] CTD PMID:20434464 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression ISO Eugenol results in increased expression of BDNF mRNA CTD PMID:15157811 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BID mRNA] CTD PMID:20434464 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO Eugenol results in increased expression of BMP6 mRNA CTD PMID:17374397 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO Eugenol results in decreased expression of BUB1 mRNA CTD PMID:17374397 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G Calcrl calcitonin receptor like receptor increases expression ISO Eugenol results in increased expression of CALCRL mRNA CTD PMID:17374397 NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
increases cleavage
ISO
EXP
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP3 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP3 protein]
Eugenol results in increased expression of CASP3 mRNA
Eugenol results in increased activity of CASP3 protein
Eugenol inhibits the reaction [Chlorpyrifos results in increased expression of CASP3 protein]; Eugenol inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]
Eugenol results in increased expression of CASP3 protein modified form
Eugenol results in increased cleavage of CASP3 protein
CTD PMID:20434464 PMID:20537511 PMID:21656368 PMID:25455450 PMID:30518369 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 increases expression ISO Eugenol results in increased expression of CASP7 mRNA CTD PMID:30518369 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
increases activity
ISO Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP9 protein]
Eugenol results in increased expression of CASP9 mRNA
Eugenol results in increased activity of CASP9 protein
CTD PMID:20434464 PMID:25455450 PMID:30518369 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase increases expression
multiple interactions
ISO
EXP
Eugenol results in increased expression of CAT mRNA
Eugenol inhibits the reaction [Acetic Acid results in increased activity of CAT protein]; Eugenol inhibits the reaction [Chlorpyrifos results in decreased expression of CAT protein]
CAT protein inhibits the reaction [[CYP2D6 protein co-treated with Copper] results in increased activity of Eugenol]
CTD PMID:15576237 PMID:20566472 PMID:32096903 PMID:33245926 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl12 chemokine (C-C motif) ligand 12 increases expression ISO Eugenol results in increased expression of CCL13 mRNA CTD PMID:17936526 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 increases expression ISO Eugenol results in increased expression of CCL19 mRNA CTD PMID:17936526 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
increases secretion
decreases expression
ISO Eugenol results in increased expression of CCL2 mRNA
Eugenol results in increased secretion of CCL2 protein
Eugenol results in decreased expression of CCL2 mRNA
CTD PMID:15585374 PMID:17374397 PMID:17936526 PMID:22245253 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO Eugenol results in increased expression of CCL20 mRNA CTD PMID:30806763 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression
increases secretion
ISO Eugenol results in increased expression of CCL3 mRNA
Eugenol results in increased secretion of CCL3 protein
CTD PMID:15585374 PMID:23624239 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression
increases secretion
ISO Eugenol results in increased expression of CCL4 mRNA; Eugenol results in increased expression of CCL4 protein
Eugenol results in increased secretion of CCL4 protein
CTD PMID:15585374 PMID:18353026 PMID:30806763 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccnb1 cyclin B1 multiple interactions EXP Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CCNB1 mRNA] CTD PMID:19851710 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 multiple interactions EXP Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CCND1 mRNA] CTD PMID:19851710 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 decreases expression ISO Eugenol results in decreased expression of CCR2 mRNA CTD PMID:17374397 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 increases expression ISO Eugenol results in increased expression of CCR5 mRNA CTD PMID:17936526 PMID:20713136 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 increases expression ISO Eugenol results in increased expression of CCR7 mRNA CTD PMID:17374397 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
JBrowse link
G Cd24 CD24 molecule decreases expression ISO Eugenol results in decreased expression of CD24 protein CTD PMID:31926151 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
JBrowse link
G Cd274 CD274 molecule increases expression ISO Eugenol results in increased expression of CD274 protein CTD PMID:23624239 NCBI chr 1:227,116,627...227,137,379
Ensembl chr 1:227,116,649...227,134,450
JBrowse link
G Cd36 CD36 molecule decreases expression ISO Eugenol results in decreased expression of CD36 mRNA CTD PMID:17374397 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression ISO Eugenol results in decreased expression of CD44 protein CTD PMID:31926151 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd86 CD86 molecule multiple interactions
increases expression
ISO [Dicumarol results in decreased activity of NQO1 protein] inhibits the reaction [Eugenol results in increased expression of CD86 protein] CTD PMID:12423654 PMID:20488241 PMID:21742781 PMID:23624239 PMID:30806763 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdk6 cyclin-dependent kinase 6 decreases expression ISO Eugenol results in decreased expression of CDK6 protein CTD PMID:22686307 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO
EXP
Eugenol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDKN1A protein]
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDKN1A protein]
CTD PMID:19851710 PMID:20043298 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO Eugenol results in increased expression of CDKN1B protein CTD PMID:22686307 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cish cytokine inducible SH2-containing protein decreases expression ISO Eugenol results in decreased expression of CISH mRNA CTD PMID:15618236 NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250
JBrowse link
G Clec4a3 C-type lectin domain family 4, member A3 decreases expression ISO Eugenol results in decreased expression of CLEC4A protein CTD PMID:23624239 NCBI chr 4:156,214,030...156,224,818
Ensembl chr 4:156,214,718...156,224,817
JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression ISO Eugenol affects the expression of CREB1 mRNA CTD PMID:20385217 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crem cAMP responsive element modulator increases expression ISO Eugenol results in increased expression of CREM mRNA CTD PMID:17374397 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
decreases expression
ISO Eugenol results in decreased expression of and affects the phosphorylation of and affects the localization of CTNNB1 protein
Eugenol results in decreased expression of CTNNB1 mRNA
CTD PMID:31926151 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsl cathepsin L increases expression ISO Eugenol results in increased expression of CTSL mRNA CTD PMID:17374397 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression ISO Eugenol results in increased expression of CXCL1 mRNA CTD PMID:20713136 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression
multiple interactions
ISO Eugenol results in increased expression of CXCL1 mRNA
Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 mRNA]
CTD PMID:12963494 PMID:20713136 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO Eugenol results in increased expression of CXCR4 mRNA CTD PMID:20713136 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CYCS mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CYCS protein] CTD PMID:20434464 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
decreases expression
decreases activity
ISO [CYP1A1 protein co-treated with Copper] results in increased activity of Eugenol; Eugenol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]; Eugenol inhibits the reaction [CYP1A1 protein results in increased metabolism of and results in increased activity of 9,10-Dimethyl-1,2-benzanthracene]; Eugenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
Eugenol results in increased expression of CYP1A1 mRNA
Eugenol results in decreased expression of CYP1A1 mRNA
Eugenol results in decreased activity of CYP1A1 protein
CTD PMID:15576237 PMID:17275817 PMID:20713136 PMID:22686307 PMID:29191726 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [CYP1A2 protein co-treated with Copper] results in increased activity of Eugenol CTD PMID:15576237 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
decreases activity
ISO Eugenol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; Eugenol inhibits the reaction [CYP1B1 protein results in increased metabolism of and results in increased activity of 9,10-Dimethyl-1,2-benzanthracene]
Eugenol results in decreased activity of CYP1B1 protein
CTD PMID:17275817 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression ISO Eugenol results in decreased expression of CYP27A1 mRNA CTD PMID:20713136 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions
increases metabolic processing
ISO [CYP2D6 protein co-treated with Copper] results in increased activity of Eugenol; [CYP2D6 protein results in increased metabolism of Eugenol] which results in increased abundance of 2-hydroxychavicol; [Eugenol co-treated with Copper co-treated with CYP2D6 protein] results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine; bathocuproine inhibits the reaction [[CYP2D6 protein co-treated with Copper] results in increased activity of Eugenol]; CAT protein inhibits the reaction [[CYP2D6 protein co-treated with Copper] results in increased activity of Eugenol]; methional inhibits the reaction [[CYP2D6 protein co-treated with Copper] results in increased activity of Eugenol] CTD PMID:15576237 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP
ISO
Eugenol inhibits the reaction [Thioacetamide results in increased expression of CYP2E1 protein]
[CYP2E1 protein co-treated with Copper] results in increased activity of Eugenol
CTD PMID:15576237 PMID:20036707 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 decreases expression ISO Eugenol results in decreased expression of DKC1 mRNA CTD PMID:17374397
G Dlgap5 DLG associated protein 5 decreases expression ISO Eugenol results in decreased expression of DLGAP5 mRNA CTD PMID:17374397 NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Eugenol results in increased expression of DNAJB4 mRNA CTD PMID:23999411 PMID:27965148 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions EXP [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine binds to and results in increased activity of DRD1 protein] which results in increased susceptibility to Eugenol CTD PMID:9537685 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Eugenol results in increased expression of DUSP1 mRNA CTD PMID:30806763 NCBI chr10:16,680,489...16,683,276 JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO Eugenol results in decreased expression of E2F1 mRNA; Eugenol results in decreased expression of E2F1 protein CTD PMID:15574415 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G E2f2 E2F transcription factor 2 decreases expression ISO Eugenol results in decreased expression of E2F2 mRNA; Eugenol results in decreased expression of E2F2 protein CTD PMID:15574415 NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217
JBrowse link
G E2f3 E2F transcription factor 3 decreases expression ISO Eugenol results in decreased expression of E2F3 mRNA; Eugenol results in decreased expression of E2F3 protein CTD PMID:15574415 NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253
JBrowse link
G E2f4 E2F transcription factor 4 decreases expression ISO Eugenol results in decreased expression of E2F4 mRNA CTD PMID:15574415 NCBI chr19:33,174,396...33,181,806
Ensembl chr19:33,174,410...33,181,806
JBrowse link
G E2f5 E2F transcription factor 5 decreases expression ISO Eugenol results in decreased expression of E2F5 mRNA CTD PMID:15574415 NCBI chr 2:86,997,331...87,012,901
Ensembl chr 2:86,997,332...87,012,990
JBrowse link
G E2f6 E2F transcription factor 6 increases expression ISO Eugenol results in increased expression of E2F6 mRNA CTD PMID:15574415 NCBI chr 6:39,592,224...39,608,685
Ensembl chr 6:39,592,228...39,608,683
JBrowse link
G Egfr epidermal growth factor receptor decreases expression
increases expression
ISO Eugenol results in decreased expression of EGFR protein
Eugenol results in increased expression of EGFR mRNA
CTD PMID:15618236 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO [[Eugenol results in increased activity of OLFR73 protein] which results in increased abundance of Cyclic AMP] which results in increased expression of EGR1 mRNA CTD PMID:12767924 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr2 early growth response 2 decreases expression ISO Eugenol results in decreased expression of EGR2 mRNA CTD PMID:17374397 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Emb embigin decreases expression ISO Eugenol results in decreased expression of EMB mRNA CTD PMID:17374397 NCBI chr 2:49,070,509...49,125,042
Ensembl chr 2:49,069,087...49,125,050
JBrowse link
G Epcam epithelial cell adhesion molecule decreases expression ISO Eugenol results in decreased expression of EPCAM protein
Eugenol results in decreased expression of EPCAM mRNA; Eugenol results in decreased expression of EPCAM protein
CTD PMID:31926151 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions
ISO Eugenol binds to ESR1 protein
Eugenol inhibits the reaction [Estradiol binds to ESR1 protein]
CTD PMID:12495555 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 affects binding
multiple interactions
ISO Eugenol binds to ESR2 protein
Eugenol inhibits the reaction [Estradiol binds to ESR2 protein]
CTD PMID:12495555 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G F13a1 coagulation factor XIII A1 chain decreases expression ISO Eugenol results in decreased expression of F13A1 mRNA CTD PMID:17374397 NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700
JBrowse link
G Fasn fatty acid synthase decreases expression ISO Eugenol results in decreased expression of FASN mRNA CTD PMID:21870829 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbxo9 f-box protein 9 decreases expression ISO Eugenol results in decreased expression of FBXO9 mRNA CTD PMID:17374397 NCBI chr 8:78,958,482...78,984,015
Ensembl chr 8:78,958,483...78,983,949
JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb increases expression ISO Eugenol results in increased expression of FCGR2B mRNA CTD PMID:17374397 NCBI chr13:83,191,253...83,207,776
Ensembl chr13:83,193,163...83,207,778
JBrowse link
G Fech ferrochelatase increases expression ISO Eugenol results in increased expression of FECH mRNA CTD PMID:20566472 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 multiple interactions EXP Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of FLT1 mRNA] CTD PMID:20434464 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression ISO Eugenol results in increased expression of FOSL2 mRNA CTD PMID:17374397 NCBI chr 6:24,297,898...24,319,157
Ensembl chr 6:24,300,956...24,320,034
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO Eugenol results in increased expression of FTL mRNA CTD PMID:20566472 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO Eugenol results in increased expression of G6PD mRNA CTD PMID:20566472 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions EXP Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of GADD45A mRNA] CTD PMID:19851710 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO Eugenol results in increased expression of GADD45B mRNA CTD PMID:15618236 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Eugenol results in increased expression of GCLC mRNA CTD PMID:20566472 PMID:26198647 PMID:30806763 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Eugenol results in increased expression of GCLM mRNA CTD PMID:20566472 PMID:26198647 PMID:27965148 PMID:30806763 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO Eugenol results in increased expression of GPAT3 mRNA CTD PMID:26198647 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO Eugenol results in increased expression of GPX3 mRNA CTD PMID:20566472 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases expression ISO Eugenol results in increased expression of GSK3B mRNA CTD PMID:17374397 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO Eugenol results in increased expression of GSR mRNA CTD PMID:20566472 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases activity ISO
EXP
Eugenol analog results in decreased activity of GSTA1 protein
Eugenol analog results in decreased activity of GSTA3 protein
CTD PMID:8620581 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression
decreases activity
EXP Eugenol results in increased expression of GSTA2 protein
Eugenol analog results in decreased activity of GSTA2 protein
CTD PMID:8406240 PMID:8620581 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases activity ISO
EXP
Eugenol analog results in decreased activity of GSTM1 protein CTD PMID:8620581 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases activity EXP Eugenol analog results in decreased activity of GSTM2 protein CTD PMID:8620581 NCBI chr 2:195,624,015...195,628,774 JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases activity ISO
EXP
Eugenol analog results in decreased activity of GSTP1 protein CTD PMID:8620581 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Heatr5b HEAT repeat containing 5B decreases expression ISO Eugenol results in decreased expression of HEATR5B mRNA CTD PMID:17374397 NCBI chr 6:16,243,424...16,323,439
Ensembl chr 6:16,243,461...16,323,435
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Eugenol results in increased expression of HIF1A mRNA CTD PMID:20713136 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO Eugenol results in decreased expression of HMGCR mRNA CTD PMID:21870829 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Eugenol results in increased expression of HMOX1 mRNA CTD PMID:20566472 PMID:20713136 PMID:23445166 PMID:26244607 PMID:30806763 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3 decreases expression ISO Eugenol results in decreased expression of HNRNPA3 mRNA CTD PMID:17374397 NCBI chr 3:60,578,574...60,588,755
Ensembl chr 3:60,578,673...60,588,306
JBrowse link
G Hras HRas proto-oncogene, GTPase decreases expression ISO Eugenol results in decreased expression of HRAS protein CTD PMID:20537511 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO Eugenol results in increased expression of HSPH1 mRNA CTD PMID:23999411 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Ibsp integrin-binding sialoprotein decreases expression ISO Eugenol results in decreased expression of IBSP mRNA; Eugenol results in decreased expression of IBSP protein CTD PMID:21706355 NCBI chr14:5,439,825...5,452,570
Ensembl chr14:5,439,829...5,452,693
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Eugenol results in increased expression of ICAM1 mRNA; Eugenol results in increased expression of ICAM1 protein CTD PMID:30806763 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO Eugenol results in decreased expression of IDI1 mRNA CTD PMID:17374397 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
JBrowse link
G Ifng interferon gamma increases secretion
multiple interactions
ISO Eugenol results in increased secretion of IFNG protein
[Methoxychlor co-treated with Eugenol] results in increased expression of IFNG protein; [Parathion co-treated with Eugenol] results in increased expression of IFNG protein
CTD PMID:20920556 PMID:22245253 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions EXP Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of IKBKB protein] CTD PMID:19851710 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Eugenol co-treated with Acetylcysteine] inhibits the reaction [Nicotine results in decreased secretion of IL10 protein]; Eugenol inhibits the reaction [Nicotine results in decreased expression of IL10 mRNA] CTD PMID:21237301 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il12a interleukin 12A multiple interactions ISO Eugenol inhibits the reaction [Nicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]] CTD PMID:21237301 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B multiple interactions ISO Eugenol inhibits the reaction [Nicotine results in increased expression of IL12B mRNA]; Eugenol inhibits the reaction [Nicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]] CTD PMID:21237301 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il16 interleukin 16 multiple interactions
increases secretion
ISO Eugenol results in increased expression of and results in increased secretion of IL16 protein
Eugenol results in increased secretion of IL16 protein
CTD PMID:23624239 PMID:30806763 NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130
JBrowse link
G Il18 interleukin 18 increases expression ISO Eugenol results in increased expression of IL18 protein CTD PMID:23063874 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Eugenol results in increased expression of IL1A mRNA CTD PMID:30806763 PMID:33715048 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
decreases expression
ISO [Eugenol results in increased activity of sulforaphane] which results in decreased expression of IL1B; [sulforaphane results in increased activity of Eugenol] which results in decreased expression of IL1B; Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
Eugenol results in increased expression of IL1B mRNA
Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]
Eugenol results in decreased expression of IL1B mRNA
CTD PMID:12963494 PMID:17509409 PMID:20713136 PMID:21382956 PMID:21807015 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1r2 interleukin 1 receptor type 2 increases expression ISO Eugenol results in increased expression of IL1R2 mRNA CTD PMID:20713136 PMID:30806763 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
JBrowse link
G Il2 interleukin 2 increases expression
increases secretion
ISO Eugenol results in increased expression of IL2 protein
Eugenol results in increased secretion of IL2 protein
CTD PMID:22245253 PMID:22381623 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4r interleukin 4 receptor increases expression ISO Eugenol results in increased expression of IL4RA protein CTD PMID:22381623 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion
increases expression
ISO
EXP
Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of IL6 protein]
Eugenol results in increased secretion of IL6 protein
Eugenol inhibits the reaction [Thioacetamide results in increased activity of IL6 protein]
Eugenol results in increased expression of IL6 mRNA
CTD PMID:20036707 PMID:20043298 PMID:21870829 PMID:22245253 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il7r interleukin 7 receptor increases expression ISO Eugenol results in increased expression of IL7R mRNA CTD PMID:20713136 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
JBrowse link
G Inhba inhibin subunit beta A decreases expression ISO Eugenol results in decreased expression of INHBA mRNA CTD PMID:15618236 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Ipcef1 interaction protein for cytohesin exchange factors 1 decreases expression ISO Eugenol results in decreased expression of IPCEF1 mRNA CTD PMID:17374397 NCBI chr 1:43,237,903...43,451,735
Ensembl chr 1:43,269,202...43,427,969
JBrowse link
G Itga6 integrin subunit alpha 6 increases expression ISO Eugenol results in increased expression of ITGA6 mRNA CTD PMID:17936526 NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428
JBrowse link
G Itgb1 integrin subunit beta 1 increases expression ISO Eugenol results in increased expression of ITGB1 mRNA CTD PMID:17936526 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 decreases activity ISO Eugenol results in decreased activity of KCNA5 protein CTD PMID:17720863 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 decreases expression ISO Eugenol results in decreased expression of KCNJ2 mRNA CTD PMID:17374397 NCBI chr10:96,060,849...96,071,401
Ensembl chr10:96,060,821...96,071,445
JBrowse link
G Kif23 kinesin family member 23 decreases expression ISO Eugenol results in decreased expression of KIF23 mRNA CTD PMID:17374397 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
JBrowse link
G LOC686035 similar to heat shock 70kDa protein 6 (HSP70B) increases expression ISO Eugenol results in increased expression of HSPA6 mRNA CTD PMID:23999411 NCBI chr13:83,271,340...83,275,267 JBrowse link
G LOC686683 similar to olfactory receptor 73 affects binding
multiple interactions
increases activity
ISO Eugenol binds to OLFR73 protein
[[Eugenol results in increased activity of OLFR73 protein] which results in increased abundance of Cyclic AMP] which results in increased expression of EGR1 mRNA; [Eugenol binds to and results in increased activity of OLFR73 protein] which results in increased abundance of Cyclic AMP; [Eugenol binds to and results in increased activity of OLFR73 protein] which results in increased transport of Calcium; [Eugenol binds to OLFR73 protein] which results in increased transport of Calcium; [Eugenol results in increased activity of OLFR73 protein] which results in increased abundance of Cyclic AMP; Eugenol binds to and results in increased activity of OLFR73 protein; isomethyleugenol inhibits the reaction [[Eugenol binds to OLFR73 protein] which results in increased transport of Calcium]
CTD PMID:12767924 PMID:14685265 PMID:15716417 PMID:19723634 NCBI chr 3:73,516,522...73,517,463 JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Eugenol results in increased expression of MAFF mRNA CTD PMID:20566472 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO Eugenol results in increased expression of MAFG mRNA CTD PMID:20566472 NCBI chr10:105,903,307...105,911,845
Ensembl chr10:105,903,237...105,912,026
JBrowse link
G Mafk MAF bZIP transcription factor K increases expression ISO Eugenol results in increased expression of MAFK mRNA CTD PMID:20566472 NCBI chr12:14,834,628...14,856,414
Ensembl chr12:14,833,984...14,837,048
Ensembl chr12:14,833,984...14,837,048
JBrowse link
G Mcts1 MCTS1, re-initiation and release factor decreases expression ISO Eugenol results in decreased expression of MCTS1 mRNA CTD PMID:17374397 NCBI chr  X:117,350,723...117,362,504
Ensembl chr  X:117,350,889...117,362,504
JBrowse link
G Me1 malic enzyme 1 increases expression ISO Eugenol results in increased expression of ME1 mRNA CTD PMID:20566472 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO Eugenol results in increased expression of MGST1 mRNA CTD PMID:20566472 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases expression
EXP
ISO
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of and results in increased activity of MMP2 protein]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MMP2 mRNA]
Eugenol results in decreased expression of MMP2 mRNA
CTD PMID:20434464 PMID:30518369 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
EXP
ISO
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of and results in increased activity of MMP9 protein]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MMP9 mRNA]
Eugenol results in decreased expression of MMP9 mRNA
CTD PMID:20434464 PMID:30518369 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Eugenol inhibits the reaction [Acetic Acid results in increased activity of MPO protein]; Eugenol inhibits the reaction [Thioacetamide results in increased activity of MPO protein] CTD PMID:20036707 PMID:33245926 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mrpl35 mitochondrial ribosomal protein L35 decreases expression ISO Eugenol results in decreased expression of MRPL35 mRNA CTD PMID:17374397 NCBI chr 4:103,865,812...103,876,687
Ensembl chr 4:103,865,812...103,880,887
JBrowse link
G Ms4a7 membrane spanning 4-domains A7 increases expression ISO Eugenol results in increased expression of MS4A7 mRNA CTD PMID:17374397 NCBI chr 1:207,968,761...207,984,812
Ensembl chr 1:207,968,761...207,983,260
JBrowse link
G Mt3 metallothionein 3 increases expression ISO Eugenol results in increased expression of MT3 mRNA CTD PMID:15157811 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
JBrowse link
G Mxd1 max dimerization protein 1 increases expression ISO Eugenol results in increased expression of MXD1 mRNA CTD PMID:20713136 NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751
JBrowse link
G Myb MYB proto-oncogene, transcription factor decreases expression ISO Eugenol results in decreased expression of MYB mRNA CTD PMID:17374397 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO Eugenol inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Croton Oil] results in increased expression of MYC protein] CTD PMID:20537511 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression ISO Eugenol results in increased expression of NAMPT mRNA CTD PMID:17374397 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects expression
multiple interactions
ISO Eugenol affects the expression of NFE2L2 protein
Eugenol promotes the reaction [NFE2L2 protein results in increased expression of NQO1 mRNA]
CTD PMID:17275817 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
affects expression
ISO
EXP
Eugenol inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]
Eugenol affects the expression of NFKB1 mRNA
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 protein]
CTD PMID:10871845 PMID:19851710 PMID:20385217 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP
ISO
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of NFKBIA mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of NFKBIA protein]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKBIA protein modified form]
Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NFKBIA protein modified form]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased degradation of NFKBIA protein]
CTD PMID:12963494 PMID:19851710 PMID:20043298 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NOS2 protein]; Eugenol inhibits the reaction [Nicotine results in increased expression of NOS2 mRNA]; Eugenol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] CTD PMID:20043298 PMID:21237301 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Notch1 notch receptor 1 decreases expression ISO Eugenol results in decreased expression of NOTCH1 protein
Eugenol results in decreased expression of NOTCH1 mRNA; Eugenol results in decreased expression of NOTCH1 protein
CTD PMID:31926151 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
increases activity
multiple interactions
ISO Eugenol results in increased expression of NQO1 mRNA; Eugenol results in increased expression of NQO1 protein
Eugenol results in increased activity of NQO1 protein
[Dicumarol results in decreased activity of NQO1 protein] inhibits the reaction [Eugenol results in increased expression of CD86 protein]; Eugenol promotes the reaction [NFE2L2 protein results in increased expression of NQO1 mRNA]
CTD PMID:17275817 PMID:20566472 PMID:21742781 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression ISO Eugenol results in increased expression of NR1I2 mRNA CTD PMID:29933105 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nup88 nucleoporin 88 increases expression ISO Eugenol results in increased expression of NUP88 mRNA CTD PMID:17374397 NCBI chr10:55,667,903...55,692,249
Ensembl chr10:55,667,906...55,692,257
JBrowse link
G P2rx3 purinergic receptor P2X 3 multiple interactions EXP Eugenol inhibits the reaction [P2RX3 protein affects the activity of Adenosine Triphosphate] CTD PMID:19967073 NCBI chr 3:70,080,850...70,124,664
Ensembl chr 3:70,080,851...70,125,178
JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase decreases expression ISO Eugenol results in decreased expression of PAICS mRNA CTD PMID:17374397 NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO Eugenol affects the reaction [Methylnitronitrosoguanidine affects the cleavage of PARP1 protein] CTD PMID:20434464 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO
EXP
Eugenol inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA protein]
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA protein]
CTD PMID:19851710 PMID:20043298 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pde4b phosphodiesterase 4B increases expression ISO Eugenol results in increased expression of PDE4B mRNA CTD PMID:17374397 NCBI chr 5:116,799,827...117,367,707
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO Eugenol results in increased expression of PGD mRNA CTD PMID:20566472 NCBI chr 5:159,582,746...159,598,945 JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein increases expression ISO Eugenol results in increased expression of PICALM mRNA CTD PMID:17374397 NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression EXP
ISO
Eugenol results in increased expression of PIK3R1 mRNA CTD PMID:20724125 PMID:21870829 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Plat plasminogen activator, tissue type increases expression ISO Eugenol results in increased expression of PLAT mRNA CTD PMID:17374397 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Eugenol results in increased expression of PMAIP1 mRNA CTD PMID:20713136 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Pou5f1 POU class 5 homeobox 1 decreases expression ISO Eugenol results in decreased expression of POU5F1 protein
Eugenol results in decreased expression of POU5F1 mRNA; Eugenol results in decreased expression of POU5F1 protein
CTD PMID:31926151 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases expression
ISO Eugenol analog binds to and results in increased activity of PPARG protein
Eugenol results in increased expression of PPARG mRNA
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Eugenol analog binds to and results in increased activity of PPARG protein]; Eugenol analog binds to and results in increased activity of PPARG protein
CTD PMID:20064974 PMID:21870829 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppbp pro-platelet basic protein multiple interactions
increases expression
ISO Eugenol results in increased expression of and results in increased secretion of PPBP protein
Eugenol results in increased expression of PPBP mRNA
CTD PMID:23624239 NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130
JBrowse link
G Prdx3 peroxiredoxin 3 decreases expression ISO Eugenol results in decreased expression of PRDX3 mRNA CTD PMID:17374397 NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
JBrowse link
G Ptger3 prostaglandin E receptor 3 decreases expression ISO Eugenol results in decreased expression of PTGER3 mRNA CTD PMID:17374397 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO Eugenol results in increased expression of PTGR1 mRNA CTD PMID:20566472 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
decreases expression
ISO
EXP
Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA]; Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]
Eugenol results in increased expression of PTGS2 mRNA
Eugenol results in decreased expression of PTGS2 mRNA
Eugenol inhibits the reaction [Thioacetamide results in increased expression of PTGS2 protein]; Eugenol inhibits the reaction [Thioacetamide results in increased expression of PTGS2]
Eugenol inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] which results in increased abundance of Dinoprostone]; Eugenol inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] which results in increased metabolism of Arachidonic Acid]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Eugenol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
CTD PMID:12757841 PMID:16101137 PMID:17509409 PMID:20036707 PMID:20043298 More... NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression ISO Eugenol results in decreased expression of RB1 protein CTD PMID:22686307 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs multiple interactions EXP Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of RECK mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of RECK protein] CTD PMID:20434464 NCBI chr 5:58,102,915...58,169,513
Ensembl chr 5:58,102,981...58,169,502
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP
Eugenol inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]
Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RELA protein]
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RELA mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RELA protein]
CTD PMID:10871845 PMID:19851710 PMID:20043298 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G RGD1311164 similar to DNA segment, Chr 6, Wayne State University 163, expressed decreases expression ISO Eugenol results in decreased expression of C12ORF4 mRNA CTD PMID:17374397 NCBI chr 4:159,772,693...159,809,322
Ensembl chr 4:159,772,786...159,806,382
JBrowse link
G Rgs1 regulator of G-protein signaling 1 increases expression ISO Eugenol results in increased expression of RGS1 mRNA CTD PMID:17374397 PMID:20713136 NCBI chr13:56,018,529...56,022,939
Ensembl chr13:56,018,554...56,022,984
JBrowse link
G Rpl27a ribosomal protein L27a increases expression ISO Eugenol results in increased expression of RPL27A mRNA CTD PMID:17374397 NCBI chr 1:163,539,732...163,542,771 JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO Eugenol results in increased expression of RRM2B mRNA CTD PMID:21704725 NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression ISO Eugenol results in increased expression of SAT1 mRNA CTD PMID:17374397 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Sdc2 syndecan 2 increases expression ISO Eugenol results in increased expression of SDC2 mRNA CTD PMID:17374397 NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081
JBrowse link
G Septin11 septin 11 decreases expression ISO Eugenol results in decreased expression of SEPTIN11 mRNA CTD PMID:17374397 NCBI chr14:14,844,759...14,990,856
Ensembl chr14:14,844,580...14,990,853
JBrowse link
G Serpinb3 serpin family B member 3 increases expression ISO Eugenol results in increased expression of SERPINB3 mRNA CTD PMID:30806763 NCBI chr13:23,274,120...23,280,082
Ensembl chr13:23,274,484...23,313,682
JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 decreases expression ISO Eugenol results in decreased expression of SLAMF1 mRNA CTD PMID:20713136 NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497
JBrowse link
G Slc16a10 solute carrier family 16 member 10 increases expression ISO Eugenol results in increased expression of SLC16A10 mRNA CTD PMID:17374397 NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839
JBrowse link
G Slc2a3 solute carrier family 2 member 3 increases expression ISO Eugenol results in increased expression of SLC2A3 mRNA CTD PMID:17374397 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO
EXP
Eugenol results in increased expression of SLC2A4 mRNA CTD PMID:20724125 PMID:21870829 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Eugenol results in increased expression of SLC7A11 mRNA CTD PMID:26198647 PMID:30806763 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Sod1 superoxide dismutase 1 increases expression
decreases expression
multiple interactions
ISO Eugenol results in increased expression of SOD1 mRNA
Eugenol results in decreased expression of SOD1 mRNA; Eugenol results in decreased expression of SOD1 protein
Acetylcysteine promotes the reaction [Eugenol results in decreased expression of SOD1 mRNA]; Glutathione promotes the reaction [Eugenol results in decreased expression of SOD1 mRNA]
CTD PMID:16101137 PMID:20566472 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 increases expression
decreases expression
multiple interactions
ISO Eugenol results in increased expression of SOD2 mRNA
Eugenol results in decreased expression of SOD2 mRNA; Eugenol results in decreased expression of SOD2 protein
Acetylcysteine promotes the reaction [Eugenol results in decreased expression of SOD2 mRNA]; Glutathione promotes the reaction [Eugenol results in decreased expression of SOD2 mRNA]
CTD PMID:16101137 PMID:20566472 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sod3 superoxide dismutase 3 increases expression ISO Eugenol results in increased expression of SOD3 mRNA CTD PMID:20566472 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO Eugenol results in increased expression of SQSTM1 mRNA CTD PMID:26198647 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Eugenol results in increased expression of SRXN1 mRNA CTD PMID:20566472 PMID:26198647 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Stat1 signal transducer and activator of transcription 1 decreases expression ISO Eugenol results in decreased expression of STAT1 mRNA CTD PMID:17374397 NCBI chr 9:49,419,561...49,459,969 JBrowse link
G Stat5b signal transducer and activator of transcription 5B increases expression ISO Eugenol results in increased expression of STAT5B mRNA CTD PMID:17374397 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 increases sulfation ISO SULT1C1 protein results in increased sulfation of Eugenol CTD PMID:9560327 NCBI chr 9:7,221,580...7,266,991
Ensembl chr 9:7,221,578...7,267,030
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions EXP Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TIMP2 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TIMP2 protein] CTD PMID:20434464 NCBI chr10:103,541,199...103,590,611 JBrowse link
G Tlr4 toll-like receptor 4 increases expression ISO Eugenol results in increased expression of TLR4 mRNA CTD PMID:17936526 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
affects expression
ISO
EXP
Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Eugenol inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]
Eugenol results in increased expression of TNF mRNA
Eugenol affects the expression of TNF mRNA
Eugenol inhibits the reaction [Chlorpyrifos results in increased expression of TNF protein]; Eugenol inhibits the reaction [Thioacetamide results in increased activity of TNF protein]
[Methoxychlor co-treated with Eugenol] results in increased expression of TNF protein; [Parathion co-treated with Eugenol] results in increased expression of TNF protein; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of TNF protein]; Eugenol inhibits the reaction [Bacterial Toxins results in increased secretion of TNF protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Eugenol inhibits the reaction [Nicotine results in increased expression of TNF mRNA]; Eugenol inhibits the reaction [Nicotine results in increased secretion of TNF protein]
CTD PMID:10871845 PMID:12963494 PMID:17509409 PMID:20036707 PMID:20043298 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO Eugenol results in increased expression of TNFAIP3 mRNA CTD PMID:20713136 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 increases expression ISO Eugenol results in increased expression of TNFAIP6 mRNA CTD PMID:17374397 PMID:20713136 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases mutagenesis
increases expression
EXP
ISO
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TP53 protein]
Eugenol results in increased mutagenesis of TP53 gene
Eugenol results in increased expression of TRP53 mRNA; Eugenol results in increased expression of TRP53 protein
Eugenol promotes the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 protein]
CTD PMID:15576237 PMID:19851710 PMID:20043298 PMID:20537511 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp63 tumor protein p63 decreases expression ISO Eugenol results in decreased expression of TP63 mRNA CTD PMID:17936526 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 multiple interactions
increases activity
EXP [2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide binds to and results in decreased activity of TRPA1 protein] which results in decreased susceptibility to Eugenol
Eugenol results in increased activity of TRPA1 protein
CTD PMID:22426238 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 multiple interactions
increases activity
ISO
EXP
Eugenol binds to and results in increased activity of TRPV3 protein
[Eugenol binds to and results in increased activity of TRPV3 protein] which results in increased transport of Calcium; Eugenol binds to and results in increased activity of TRPV3 protein
[Eugenol results in increased activity of TRPV3 protein] which results in increased transport of Calcium
CTD PMID:16617338 PMID:20086034 PMID:21593771 NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296
JBrowse link
G Txn2 thioredoxin 2 increases expression ISO Eugenol results in increased expression of TXN2 mRNA CTD PMID:20566472 NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Eugenol results in increased expression of TXNRD1 mRNA CTD PMID:20566472 PMID:23445166 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Txnrd2 thioredoxin reductase 2 increases expression ISO Eugenol results in increased expression of TXNRD2 mRNA CTD PMID:20566472 NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase increases expression ISO Eugenol results in increased expression of UGDH mRNA CTD PMID:16292757 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of Eugenol CTD PMID:14557274 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression ISO Eugenol results in increased expression of UGT1A6 mRNA CTD PMID:20566472 NCBI chr 9:88,747,229...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of Eugenol CTD PMID:14557274 NCBI chr 9:88,696,981...88,808,465 JBrowse link
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 increases metabolic processing EXP UGT2B15 protein results in increased metabolism of Eugenol CTD PMID:7574722 NCBI chr14:20,768,015...20,783,599
Ensembl chr14:20,768,015...20,783,589
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases metabolic processing ISO UGT2B17 protein results in increased metabolism of Eugenol CTD PMID:8798464 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Vdr vitamin D receptor increases expression ISO Eugenol results in increased expression of VDR mRNA CTD PMID:17374397 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
G Zbtb17 zinc finger and BTB domain containing 17 decreases expression ISO Eugenol results in decreased expression of ZBTB17 mRNA CTD PMID:17374397 NCBI chr 5:153,753,508...153,774,613
Ensembl chr 5:153,753,569...153,774,609
JBrowse link
guaiacol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin affects binding ISO Guaiacol binds to ALB protein CTD PMID:11334365 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Car1 carbonic anhydrase 1 decreases activity ISO Guaiacol results in decreased activity of CA1 protein CTD PMID:19231207 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO Guaiacol results in decreased activity of CA2 protein CTD PMID:19231207 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO COMT mutant form inhibits the reaction [catechol results in increased abundance of Guaiacol] CTD PMID:24141029 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Guaiacol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:17465205 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 increases sulfation ISO SULT1C1 protein results in increased sulfation of Guaiacol CTD PMID:9560327 NCBI chr 9:7,221,580...7,266,991
Ensembl chr 9:7,221,578...7,267,030
JBrowse link
isoeugenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor increases activity
affects localization
multiple interactions
ISO isoeugenol results in increased activity of AHR protein
isoeugenol affects the localization of AHR protein
3'-methoxy-4'-nitroflavone inhibits the reaction [isoeugenol results in increased activity of AHR protein]
CTD PMID:16972787 PMID:22686307 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor increases expression ISO isoeugenol results in increased expression of AHRR mRNA CTD PMID:22686307 NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression ISO isoeugenol results in increased expression of AKR1B1 mRNA CTD PMID:20566472 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO isoeugenol results in increased expression of AKR1B10 mRNA CTD PMID:20566472 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression
increases activity
ISO isoeugenol results in increased expression of AKR1C2 mRNA
isoeugenol results in increased activity of AKR1C2 promoter
CTD PMID:20491607 PMID:21195160 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression ISO isoeugenol results in increased expression of AKR1C3 mRNA CTD PMID:20566472 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Ar androgen receptor affects binding EXP isoeugenol binds to AR protein CTD PMID:14565775 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO isoeugenol results in increased expression of ATF3 mRNA CTD PMID:23999411 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Cat catalase increases expression ISO isoeugenol results in increased expression of CAT mRNA CTD PMID:20566472 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases secretion ISO isoeugenol results in decreased secretion of CCL2 protein CTD PMID:20488241 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl27 C-C motif chemokine ligand 27 increases expression ISO isoeugenol results in increased expression of CCL27 mRNA CTD PMID:17936526 NCBI chr 5:56,941,402...56,948,511
Ensembl chr 5:56,941,402...56,948,506
JBrowse link
G Cd274 CD274 molecule increases expression ISO isoeugenol results in increased expression of CD274 protein CTD PMID:20488241 NCBI chr 1:227,116,627...227,137,379
Ensembl chr 1:227,116,649...227,134,450
JBrowse link
G Cdk6 cyclin-dependent kinase 6 decreases expression ISO isoeugenol results in decreased expression of CDK6 protein CTD PMID:22686307 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO isoeugenol results in increased expression of CDKN1B protein CTD PMID:22686307 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO isoeugenol results in increased expression of CXCL2 protein CTD PMID:23178550 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO isoeugenol results in increased expression of CYP1A1 mRNA CTD PMID:20491607 PMID:22686307 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO isoeugenol results in increased expression of DNAJB4 mRNA CTD PMID:23999411 PMID:27965148 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
JBrowse link
G Fech ferrochelatase increases expression ISO isoeugenol results in increased expression of FECH mRNA CTD PMID:20566472 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO isoeugenol results in increased expression of FTL mRNA CTD PMID:20566472 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO isoeugenol results in increased expression of G6PD mRNA CTD PMID:20566472 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO isoeugenol results in increased expression of GCLC mRNA CTD PMID:20566472 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO isoeugenol results in increased expression of GCLM mRNA CTD PMID:20566472 PMID:23999411 PMID:27965148 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO isoeugenol results in increased expression of GPX3 mRNA CTD PMID:20566472 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO isoeugenol results in increased expression of GSR mRNA CTD PMID:20566472 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO isoeugenol results in increased expression of HMOX1 mRNA CTD PMID:20491607 PMID:20566472 PMID:23445166 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO isoeugenol results in increased expression of HSPH1 mRNA CTD PMID:23999411 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Ifng interferon gamma increases secretion ISO isoeugenol results in increased secretion of IFNG protein CTD PMID:22245253 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il18 interleukin 18 increases expression ISO isoeugenol results in increased expression of IL18 protein CTD PMID:23063874 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO isoeugenol results in increased expression of IL1A protein CTD PMID:23178550 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il2 interleukin 2 multiple interactions
increases secretion
ISO isoeugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; isoeugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]
isoeugenol results in increased secretion of IL2 protein
CTD PMID:17630204 PMID:22245253 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il6 interleukin 6 increases secretion ISO isoeugenol results in increased secretion of IL6 protein CTD PMID:22245253 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G LOC686035 similar to heat shock 70kDa protein 6 (HSP70B) increases expression ISO isoeugenol results in increased expression of HSPA6 mRNA CTD PMID:23999411 NCBI chr13:83,271,340...83,275,267 JBrowse link
G LOC686683 similar to olfactory receptor 73 multiple interactions ISO isoeugenol binds to and results in decreased activity of OLFR73 protein; isoeugenol binds to and results in increased activity of OLFR73 protein CTD PMID:15574817 PMID:21142015 NCBI chr 3:73,516,522...73,517,463 JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO isoeugenol results in increased expression of MAFF mRNA CTD PMID:20491607 PMID:20566472 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO isoeugenol results in increased expression of MAFG mRNA CTD PMID:20566472 NCBI chr10:105,903,307...105,911,845
Ensembl chr10:105,903,237...105,912,026
JBrowse link
G Mafk MAF bZIP transcription factor K increases expression ISO isoeugenol results in increased expression of MAFK mRNA CTD PMID:20566472 NCBI chr12:14,834,628...14,856,414
Ensembl chr12:14,833,984...14,837,048
Ensembl chr12:14,833,984...14,837,048
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO isoeugenol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; MAPK1 protein affects the reaction [isoeugenol affects the expression of NOS2] CTD PMID:17698059 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO isoeugenol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]; MAPK3 protein affects the reaction [isoeugenol affects the expression of NOS2] CTD PMID:17698059 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Me1 malic enzyme 1 increases expression ISO isoeugenol results in increased expression of ME1 mRNA CTD PMID:20566472 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO isoeugenol results in increased expression of MGST1 mRNA CTD PMID:20566472 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO isoeugenol inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]] CTD PMID:10871845 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO isoeugenol inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; NFKBIA protein affects the reaction [isoeugenol affects the expression of NOS2] CTD PMID:17698059 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO isoeugenol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; isoeugenol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; MAPK1 protein affects the reaction [isoeugenol affects the expression of NOS2]; MAPK3 protein affects the reaction [isoeugenol affects the expression of NOS2]; NFKBIA protein affects the reaction [isoeugenol affects the expression of NOS2] CTD PMID:17698059 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO isoeugenol results in increased expression of NQO1 mRNA CTD PMID:20491607 PMID:20566472 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO isoeugenol results in increased expression of PGD mRNA CTD PMID:20566472 NCBI chr 5:159,582,746...159,598,945 JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO isoeugenol results in increased expression of PTGR1 mRNA CTD PMID:20566472 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression ISO isoeugenol results in decreased expression of RB1 protein CTD PMID:22686307 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO isoeugenol inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]
isoeugenol inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]
CTD PMID:10871845 PMID:17698059 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Socs3 suppressor of cytokine signaling 3 increases expression
multiple interactions
ISO isoeugenol results in increased expression of SOCS3 mRNA; isoeugenol results in increased expression of SOCS3 protein
KT 5720 inhibits the reaction [isoeugenol results in increased expression of SOCS3 mRNA]
CTD PMID:21969073 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Sod1 superoxide dismutase 1 increases expression ISO isoeugenol results in increased expression of SOD1 mRNA CTD PMID:20566472 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO isoeugenol results in increased expression of SOD2 mRNA CTD PMID:20566472 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sod3 superoxide dismutase 3 increases expression ISO isoeugenol results in increased expression of SOD3 mRNA CTD PMID:20566472 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO isoeugenol results in increased expression of SRXN1 mRNA CTD PMID:20566472 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Tlr2 toll-like receptor 2 increases expression ISO isoeugenol results in increased expression of TLR2 mRNA CTD PMID:17936526 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases secretion
ISO isoeugenol inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]
isoeugenol results in increased secretion of TNF protein
CTD PMID:10871845 PMID:22245253 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Trim16 tripartite motif-containing 16 multiple interactions
increases expression
ISO [Indomethacin co-treated with isoeugenol] results in increased expression of TRIM16 mRNA
isoeugenol results in increased expression of TRIM16 mRNA
CTD PMID:21284934 NCBI chr10:47,485,982...47,509,010 JBrowse link
G Txn2 thioredoxin 2 increases expression ISO isoeugenol results in increased expression of TXN2 mRNA CTD PMID:20566472 NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO isoeugenol results in increased expression of TXNRD1 mRNA CTD PMID:20566472 PMID:23445166 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Txnrd2 thioredoxin reductase 2 increases expression ISO isoeugenol results in increased expression of TXNRD2 mRNA CTD PMID:20566472 NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression ISO isoeugenol results in increased expression of UGT1A6 mRNA CTD PMID:20566472 NCBI chr 9:88,747,229...88,808,465 JBrowse link
G Zfp36 zinc finger protein 36 increases expression
multiple interactions
ISO isoeugenol results in increased expression of ZFP36 protein
KT 5720 inhibits the reaction [isoeugenol results in increased expression of ZFP36 protein]; SB 203580 inhibits the reaction [isoeugenol results in increased expression of ZFP36 protein]
CTD PMID:21969073 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
O-methyleugenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aass aminoadipate-semialdehyde synthase decreases expression ISO methyleugenol results in decreased expression of AASS mRNA CTD PMID:32234424 NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136
JBrowse link
G Abat 4-aminobutyrate aminotransferase decreases expression ISO methyleugenol results in decreased expression of ABAT mRNA CTD PMID:32234424 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO methyleugenol results in decreased expression of ABCA1 mRNA CTD PMID:32234424 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abca6 ATP binding cassette subfamily A member 6 decreases expression ISO methyleugenol results in decreased expression of ABCA6 mRNA CTD PMID:32234424 NCBI chr10:95,142,805...95,212,087
Ensembl chr10:95,142,966...95,211,530
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression ISO methyleugenol results in decreased expression of ABCB11 mRNA CTD PMID:32234424 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases expression ISO methyleugenol results in decreased expression of ABCB4 mRNA CTD PMID:32234424 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 decreases expression ISO methyleugenol results in decreased expression of ABCC6 mRNA CTD PMID:32234424 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 decreases expression ISO methyleugenol results in decreased expression of ABCC9 mRNA CTD PMID:32234424 NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 decreases expression ISO methyleugenol results in decreased expression of ABCG5 mRNA CTD PMID:32234424 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 decreases expression ISO methyleugenol results in decreased expression of ABCG8 mRNA CTD PMID:32234424 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase decreases expression ISO methyleugenol results in decreased expression of ABHD2 mRNA CTD PMID:32234424 NCBI chr 1:133,217,403...133,298,564
Ensembl chr 1:133,217,375...133,299,061
JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A decreases expression ISO methyleugenol results in decreased expression of ACAA1 mRNA CTD PMID:32234424 NCBI chr 8:119,079,401...119,088,624
Ensembl chr 8:119,079,775...119,088,624
JBrowse link
G Acacb acetyl-CoA carboxylase beta decreases expression ISO methyleugenol results in decreased expression of ACACB mRNA CTD PMID:32234424 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 decreases expression ISO methyleugenol results in decreased expression of ACAT2 mRNA CTD PMID:32234424 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Ache acetylcholinesterase increases expression ISO methyleugenol results in increased expression of ACHE mRNA CTD PMID:32234424 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase decreases expression ISO methyleugenol results in decreased expression of ACMSD mRNA CTD PMID:32234424 NCBI chr13:39,200,486...39,244,337
Ensembl chr13:39,200,314...39,245,209
JBrowse link
G Acot1 acyl-CoA thioesterase 1 decreases expression ISO methyleugenol results in decreased expression of ACOT1 mRNA CTD PMID:32234424 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
JBrowse link
G Acot11 acyl-CoA thioesterase 11 decreases expression ISO methyleugenol results in decreased expression of ACOT11 mRNA CTD PMID:32234424 NCBI chr 5:121,523,833...121,581,699
Ensembl chr 5:121,527,435...121,581,538
JBrowse link
G Acot12 acyl-CoA thioesterase 12 decreases expression ISO methyleugenol results in decreased expression of ACOT12 mRNA CTD PMID:32234424 NCBI chr 2:22,986,867...23,027,538
Ensembl chr 2:22,986,626...23,027,536
JBrowse link
G Acox2 acyl-CoA oxidase 2 decreases expression ISO methyleugenol results in decreased expression of ACOX2 mRNA CTD PMID:32234424 NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO methyleugenol results in decreased expression of ACSL1 mRNA CTD PMID:32234424 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 decreases expression ISO methyleugenol results in decreased expression of ACSL4 mRNA CTD PMID:32234424 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression ISO methyleugenol results in decreased expression of ACSL5 mRNA CTD PMID:32234424 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Acsm2 acyl-CoA synthetase medium-chain family member 2 decreases expression ISO methyleugenol results in decreased expression of ACSM2A mRNA CTD PMID:32234424 NCBI chr 1:173,916,368...173,955,116
Ensembl chr 1:173,916,368...173,955,116
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 decreases expression ISO methyleugenol results in decreased expression of ACSM3 mRNA CTD PMID:32234424 NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184
JBrowse link
G Acsm5 acyl-CoA synthetase medium-chain family member 5 decreases expression ISO methyleugenol results in decreased expression of ACSM5 mRNA CTD PMID:32234424 NCBI chr 1:173,870,873...173,896,838
Ensembl chr 1:173,863,041...173,898,588
JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 decreases expression ISO methyleugenol results in decreased expression of ACSS1 mRNA CTD PMID:32234424 NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 decreases expression ISO methyleugenol results in decreased expression of ACSS2 mRNA CTD PMID:32234424 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
JBrowse link
G Actl10 actin-like 10 increases expression ISO methyleugenol results in increased expression of ACTL10 mRNA CTD PMID:32234424 NCBI chr 3:143,055,425...143,058,577
Ensembl chr 3:143,057,402...143,058,442
JBrowse link
G Acyp2 acylphosphatase 2 decreases expression ISO methyleugenol results in decreased expression of ACYP2 mRNA CTD PMID:32234424 NCBI chr14:104,201,894...104,371,415
Ensembl chr14:104,201,895...104,371,386
JBrowse link
G Adam19 ADAM metallopeptidase domain 19 increases expression ISO methyleugenol results in increased expression of ADAM19 mRNA CTD PMID:32234424 NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105
JBrowse link
G Adamts17 ADAM metallopeptidase with thrombospondin type 1 motif, 17 decreases expression ISO methyleugenol results in decreased expression of ADAMTS17 mRNA CTD PMID:32234424 NCBI chr 1:120,445,800...120,768,204
Ensembl chr 1:120,445,749...120,768,202
JBrowse link
G Adamts3 ADAM metallopeptidase with thrombospondin type 1, motif 3 decreases expression ISO methyleugenol results in decreased expression of ADAMTS3 mRNA CTD PMID:32234424 NCBI chr14:18,231,051...18,437,773
Ensembl chr14:18,231,165...18,435,556
JBrowse link
G Adamts6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 decreases expression ISO methyleugenol results in decreased expression of ADAMTS6 mRNA CTD PMID:32234424 NCBI chr 2:35,421,483...35,633,305
Ensembl chr 2:35,421,510...35,633,298
JBrowse link
G Adamtsl3 ADAMTS-like 3 decreases expression ISO methyleugenol results in decreased expression of ADAMTSL3 mRNA CTD PMID:32234424 NCBI chr 1:136,288,793...136,596,986
Ensembl chr 1:136,288,793...136,596,986
JBrowse link
G Adarb2 adenosine deaminase, RNA-specific, B2 decreases expression ISO methyleugenol results in decreased expression of ADARB2 mRNA CTD PMID:32234424 NCBI chr17:61,750,437...62,300,984
Ensembl chr17:61,756,067...62,300,831
JBrowse link
G Adcy5 adenylate cyclase 5 decreases expression ISO methyleugenol results in decreased expression of ADCY5 mRNA CTD PMID:32234424 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974
JBrowse link
G Adcy8 adenylate cyclase 8 decreases expression ISO methyleugenol results in decreased expression of ADCY8 mRNA CTD PMID:32234424 NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911
JBrowse link
G Adgrf4 adhesion G protein-coupled receptor F4 increases expression ISO methyleugenol results in increased expression of ADGRF4 mRNA CTD PMID:32234424 NCBI chr 9:18,272,050...18,303,219
Ensembl chr 9:18,272,050...18,303,217
JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 increases expression ISO methyleugenol results in increased expression of ADGRG1 mRNA CTD PMID:32234424 NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108
JBrowse link
G Adgrg7 adhesion G protein-coupled receptor G7 decreases expression ISO methyleugenol results in decreased expression of ADGRG7 mRNA CTD PMID:32234424 NCBI chr11:43,808,101...43,877,539
Ensembl chr11:43,813,801...43,876,316
JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 decreases expression ISO methyleugenol results in decreased expression of ADGRV1 mRNA CTD PMID:32234424 NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide decreases expression ISO methyleugenol results in decreased expression of ADH4 mRNA CTD PMID:32234424 NCBI chr 2:226,948,717...226,966,747 JBrowse link
G Adk adenosine kinase decreases expression ISO methyleugenol results in decreased expression of ADK mRNA CTD PMID:32234424 NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510
JBrowse link
G Adra1a adrenoceptor alpha 1A decreases expression ISO methyleugenol results in decreased expression of ADRA1A mRNA CTD PMID:32234424 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
JBrowse link
G Aff2 AF4/FMR2 family, member 2 decreases expression ISO methyleugenol results in decreased expression of AFF2 mRNA CTD PMID:32234424 NCBI chr  X:147,928,130...148,432,484
Ensembl chr  X:147,928,407...148,429,995
JBrowse link
G Aff3 AF4/FMR2 family, member 3 decreases expression ISO methyleugenol results in decreased expression of AFF3 mRNA CTD PMID:32234424 NCBI chr 9:40,399,109...40,856,716
Ensembl chr 9:40,404,375...40,857,247
JBrowse link
G Afg1l AFG1 like ATPase decreases expression ISO methyleugenol results in decreased expression of AFG1L mRNA CTD PMID:32234424 NCBI chr20:45,798,344...45,967,997 JBrowse link
G Afm afamin decreases expression ISO methyleugenol results in decreased expression of AFM mRNA CTD PMID:32234424 NCBI chr14:17,531,026...17,563,868
Ensembl chr14:17,531,024...17,563,870
JBrowse link
G Agmo alkylglycerol monooxygenase decreases expression ISO methyleugenol results in decreased expression of AGMO mRNA CTD PMID:32234424 NCBI chr 6:53,986,236...54,317,838
Ensembl chr 6:53,986,292...54,317,623
JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 decreases expression ISO methyleugenol results in decreased expression of AGPAT2 mRNA CTD PMID:32234424 NCBI chr 3:9,416,842...9,428,567
Ensembl chr 3:9,416,843...9,428,371
JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member increases expression ISO methyleugenol results in increased expression of AGR2 mRNA CTD PMID:32234424 NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371
JBrowse link
G Agt angiotensinogen decreases expression ISO methyleugenol results in decreased expression of AGT mRNA CTD PMID:32234424 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase decreases expression ISO methyleugenol results in decreased expression of AGXT mRNA CTD PMID:32234424 NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336
JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 decreases expression ISO methyleugenol results in decreased expression of AGXT2 mRNA CTD PMID:32234424 NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926
JBrowse link
G Ahsg alpha-2-HS-glycoprotein decreases expression ISO methyleugenol results in decreased expression of AHSG mRNA CTD PMID:32234424 NCBI chr11:78,117,903...78,145,956 JBrowse link
G Aig1 androgen-induced 1 decreases expression ISO methyleugenol results in decreased expression of AIG1 mRNA CTD PMID:32234424 NCBI chr 1:8,046,430...8,269,276
Ensembl chr 1:8,046,430...8,269,084
JBrowse link
G Akap12 A-kinase anchoring protein 12 increases expression ISO methyleugenol results in increased expression of AKAP12 mRNA CTD PMID:32234424 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886
JBrowse link
G Akap6 A-kinase anchoring protein 6 decreases expression ISO methyleugenol results in decreased expression of AKAP6 mRNA CTD PMID:32234424 NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression ISO methyleugenol results in increased expression of AKR1B1 mRNA CTD PMID:32234424 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO methyleugenol results in increased expression of AKR1B10 mRNA CTD PMID:32234424 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 increases expression ISO methyleugenol results in increased expression of AKR1B15 mRNA CTD PMID:32234424 NCBI chr 4:62,997,241...63,009,815 JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 decreases expression ISO methyleugenol results in decreased expression of AKR1C4 mRNA CTD PMID:32234424 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 decreases expression ISO methyleugenol results in decreased expression of AKR1D1 mRNA CTD PMID:32234424 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 decreases expression ISO methyleugenol results in decreased expression of AKR7A3 mRNA CTD PMID:32234424 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Alb albumin decreases expression ISO methyleugenol results in decreased expression of ALB mRNA CTD PMID:32234424 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases expression ISO methyleugenol results in increased expression of ALDH3A1 mRNA CTD PMID:32234424 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681
JBrowse link
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 decreases expression ISO methyleugenol results in decreased expression of ALDH4A1 mRNA CTD PMID:32234424 NCBI chr 5:151,880,002...151,905,491 JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 decreases expression ISO methyleugenol results in decreased expression of ALDH6A1 mRNA CTD PMID:32234424 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 decreases expression ISO methyleugenol results in decreased expression of ALDH8A1 mRNA CTD PMID:32234424 NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385
JBrowse link
G Aldob aldolase, fructose-bisphosphate B decreases expression ISO methyleugenol results in decreased expression of ALDOB mRNA CTD PMID:32234424 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116
JBrowse link
G Alox5 arachidonate 5-lipoxygenase increases expression ISO methyleugenol results in increased expression of ALOX5 mRNA CTD PMID:32234424 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Alpk2 alpha-kinase 2 increases expression ISO methyleugenol results in increased expression of ALPK2 mRNA CTD PMID:32234424 NCBI chr18:58,775,603...58,906,150
Ensembl chr18:58,775,605...58,906,258
JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor decreases expression ISO methyleugenol results in decreased expression of AMBP mRNA CTD PMID:32234424 NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331
JBrowse link
G Amotl1 angiomotin-like 1 decreases expression ISO methyleugenol results in decreased expression of AMOTL1 mRNA CTD PMID:32234424 NCBI chr 8:11,348,651...11,467,564
Ensembl chr 8:11,353,674...11,467,573
JBrowse link
G Ang angiogenin decreases expression ISO methyleugenol results in decreased expression of ANG mRNA CTD PMID:32234424 NCBI chr15:24,317,733...24,323,361 JBrowse link
G Angptl3 angiopoietin-like 3 decreases expression ISO methyleugenol results in decreased expression of ANGPTL3 mRNA CTD PMID:32234424 NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957
JBrowse link
G Angptl8 angiopoietin-like 8 decreases expression ISO methyleugenol results in decreased expression of ANGPTL8 mRNA CTD PMID:32234424 NCBI chr 8:20,376,462...20,378,488
Ensembl chr 8:20,376,462...20,378,490
JBrowse link
G Ank1 ankyrin 1 increases expression ISO methyleugenol results in increased expression of ANK1 mRNA CTD PMID:32234424 NCBI chr16:68,876,294...69,054,812
Ensembl chr16:68,877,504...69,054,759
JBrowse link
G Ank2 ankyrin 2 decreases expression ISO methyleugenol results in decreased expression of ANK2 mRNA CTD PMID:32234424 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
JBrowse link
G Ankrd1 ankyrin repeat domain 1 decreases expression ISO methyleugenol results in decreased expression of ANKRD1 mRNA CTD PMID:32234424 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
JBrowse link
G Ankrd2 ankyrin repeat domain 2 decreases expression ISO methyleugenol results in decreased expression of ANKRD2 mRNA CTD PMID:32234424 NCBI chr 1:240,847,111...240,856,563
Ensembl chr 1:240,847,072...240,856,566
JBrowse link
G Anks1b ankyrin repeat and sterile alpha motif domain containing 1B decreases expression ISO methyleugenol results in decreased expression of ANKS1B mRNA CTD PMID:32234424 NCBI chr 7:24,313,810...25,479,307
Ensembl chr 7:24,312,843...25,477,693
JBrowse link
G Ano1 anoctamin 1 decreases expression ISO methyleugenol results in decreased expression of ANO1 mRNA CTD PMID:32234424 NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069
JBrowse link
G Ano4 anoctamin 4 decreases expression ISO methyleugenol results in decreased expression of ANO4 mRNA CTD PMID:32234424 NCBI chr 7:23,329,015...23,738,423
Ensembl chr 7:23,329,070...23,738,434
JBrowse link
G Anxa10 annexin A10 decreases expression ISO methyleugenol results in decreased expression of ANXA10 mRNA CTD PMID:32234424 NCBI chr16:27,738,712...27,805,648
Ensembl chr16:27,738,712...27,805,648
JBrowse link
G Anxa3 annexin A3 increases expression ISO methyleugenol results in increased expression of ANXA3 mRNA CTD PMID:32234424 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Aoc1 amine oxidase, copper containing 1 decreases expression ISO methyleugenol results in decreased expression of AOC1 mRNA CTD PMID:32234424 NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840
JBrowse link
G Apba1 amyloid beta precursor protein binding family A member 1 decreases expression ISO methyleugenol results in decreased expression of APBA1 mRNA CTD PMID:32234424 NCBI chr 1:221,363,769...221,569,496
Ensembl chr 1:221,363,778...221,566,553
JBrowse link
G Apbb1ip amyloid beta precursor protein binding family B member 1 interacting protein decreases expression ISO methyleugenol results in decreased expression of APBB1IP mRNA CTD PMID:32234424 NCBI chr17:84,941,404...85,033,020
Ensembl chr17:84,982,243...85,033,010
JBrowse link
G Apcdd1l APC down-regulated 1 like increases expression ISO methyleugenol results in increased expression of APCDD1L mRNA CTD PMID:32234424 NCBI chr 3:162,587,484...162,658,362
Ensembl chr 3:162,582,252...162,658,073
JBrowse link
G Apcs amyloid P component, serum decreases expression ISO methyleugenol results in decreased expression of APCS mRNA CTD PMID:32234424 NCBI chr13:85,373,338...85,374,134
Ensembl chr13:85,373,220...85,374,298
JBrowse link
G Apmap adipocyte plasma membrane associated protein decreases expression ISO methyleugenol results in decreased expression of APMAP mRNA CTD PMID:32234424 NCBI chr 3:139,409,020...139,437,296
Ensembl chr 3:139,409,022...139,437,341
JBrowse link
G Apoa1 apolipoprotein A1 decreases expression ISO methyleugenol results in decreased expression of APOA1 mRNA CTD PMID:32234424 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa4 apolipoprotein A4 decreases expression ISO methyleugenol results in decreased expression of APOA4 mRNA CTD PMID:32234424 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoa5 apolipoprotein A5 decreases expression ISO methyleugenol results in decreased expression of APOA5 mRNA CTD PMID:32234424 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link
G Apoc3 apolipoprotein C3 decreases expression ISO methyleugenol results in decreased expression of APOC3 mRNA CTD PMID:32234424 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Apoh apolipoprotein H decreases expression ISO methyleugenol results in decreased expression of APOH mRNA CTD PMID:32234424 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
JBrowse link
G Apom apolipoprotein M decreases expression ISO methyleugenol results in decreased expression of APOM mRNA CTD PMID:32234424 NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550
JBrowse link
G Aqp4 aquaporin 4 decreases expression ISO methyleugenol results in decreased expression of AQP4 mRNA CTD PMID:32234424 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
JBrowse link
G Aqp9 aquaporin 9 decreases expression ISO methyleugenol results in decreased expression of AQP9 mRNA CTD PMID:32234424 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
JBrowse link
G Arg1 arginase 1 decreases expression ISO methyleugenol results in decreased expression of ARG1 mRNA CTD PMID:32234424 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arhgap6 Rho GTPase activating protein 6 decreases expression ISO methyleugenol results in decreased expression of ARHGAP6 mRNA CTD PMID:32234424 NCBI chr  X:24,953,464...25,490,003
Ensembl chr  X:24,953,464...25,488,663
JBrowse link
G Arhgef37 Rho guanine nucleotide exchange factor 37 increases expression ISO methyleugenol results in increased expression of ARHGEF37 mRNA CTD PMID:32234424 NCBI chr18:54,935,256...55,001,017
Ensembl chr18:54,949,110...55,000,669
JBrowse link
G Arl14 ADP-ribosylation factor like GTPase 14 increases expression ISO methyleugenol results in increased expression of ARL14 mRNA CTD PMID:32234424 NCBI chr 2:153,467,974...153,470,053
Ensembl chr 2:153,468,977...153,469,555
JBrowse link
G Arrb1 arrestin, beta 1 increases expression ISO methyleugenol results in increased expression of ARRB1 mRNA CTD PMID:32234424 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
JBrowse link
G Arsb arylsulfatase B decreases expression ISO methyleugenol results in decreased expression of ARSB mRNA CTD PMID:32234424 NCBI chr 2:25,002,210...25,162,675
Ensembl chr 2:25,002,346...25,162,671
JBrowse link
G Art3 ADP-ribosyltransferase 3 decreases expression ISO methyleugenol results in decreased expression of ART3 mRNA CTD PMID:32234424 NCBI chr14:15,637,230...15,719,442
Ensembl chr14:15,637,237...15,665,407
JBrowse link
G Arvcf ARVCF, delta catenin family member increases expression ISO methyleugenol results in increased expression of ARVCF mRNA CTD PMID:32234424 NCBI chr11:82,588,137...82,645,805
Ensembl chr11:82,587,881...82,645,805
JBrowse link
G Asb4 ankyrin repeat and SOCS box-containing 4 decreases expression ISO methyleugenol results in decreased expression of ASB4 mRNA CTD PMID:32234424 NCBI chr 4:33,506,992...33,544,630
Ensembl chr 4:33,506,992...33,544,630
JBrowse link
G Asgr1 asialoglycoprotein receptor 1 decreases expression ISO methyleugenol results in decreased expression of ASGR1 mRNA CTD PMID:32234424 NCBI chr10:54,775,727...54,779,642
Ensembl chr10:54,776,024...54,779,631
JBrowse link
G Aspdh aspartate dehydrogenase domain containing decreases expression ISO methyleugenol results in decreased expression of ASPDH mRNA CTD PMID:32234424 NCBI chr 1:94,956,327...94,960,722
Ensembl chr 1:94,958,316...94,960,722
JBrowse link
G Atl1 atlastin GTPase 1 decreases expression ISO methyleugenol results in decreased expression of ATL1 mRNA CTD PMID:32234424 NCBI chr 6:88,377,168...88,475,242
Ensembl chr 6:88,377,239...88,475,204
JBrowse link
G Atm ATM serine/threonine kinase increases phosphorylation
decreases expression
ISO
EXP
methyleugenol results in increased phosphorylation of ATM protein
methyleugenol results in decreased expression of ATM mRNA
CTD PMID:26011634 PMID:28818686 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atp13a4 ATPase 13A4 decreases expression ISO methyleugenol results in decreased expression of ATP13A4 mRNA CTD PMID:32234424 NCBI chr11:71,222,196...71,359,933
Ensembl chr11:71,226,161...71,359,933
JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 decreases expression ISO methyleugenol results in decreased expression of ATP2B2 mRNA CTD PMID:32234424 NCBI chr 4:146,896,332...147,140,665
Ensembl chr 4:146,896,332...147,140,665
JBrowse link
G Atp8b4 ATPase phospholipid transporting 8B4 (putative) decreases expression ISO methyleugenol results in decreased expression of ATP8B4 mRNA CTD PMID:32234424 NCBI chr 3:113,554,979...113,757,635
Ensembl chr 3:113,556,192...113,757,225
JBrowse link
G Atr ATR serine/threonine kinase increases phosphorylation ISO methyleugenol results in increased phosphorylation of ATR protein CTD PMID:28818686 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
JBrowse link
G Atrnl1 attractin like 1 decreases expression ISO methyleugenol results in decreased expression of ATRNL1 mRNA CTD PMID:32234424 NCBI chr 1:256,670,976...257,219,291
Ensembl chr 1:256,670,627...257,213,197
JBrowse link
G Atxn1 ataxin 1 decreases expression ISO methyleugenol results in decreased expression of ATXN1 mRNA CTD PMID:32234424 NCBI chr17:18,737,491...19,142,360
Ensembl chr17:18,737,533...19,142,360
JBrowse link
G Aurka aurora kinase A decreases expression EXP
ISO
methyleugenol results in decreased expression of AURKA mRNA CTD PMID:26011634 PMID:32234424 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
JBrowse link
G Aurkb aurora kinase B increases expression
affects expression
EXP methyleugenol results in increased expression of AURKB protein
methyleugenol affects the expression of AURKB mRNA
CTD PMID:23411599 PMID:26011634 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding decreases expression ISO methyleugenol results in decreased expression of AZGP1 mRNA CTD PMID:32234424 NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091
JBrowse link
G B3galt1 Beta-1,3-galactosyltransferase 1 decreases expression ISO methyleugenol results in decreased expression of B3GALT1 mRNA CTD PMID:32234424 NCBI chr 3:52,253,413...52,826,508
Ensembl chr 3:52,253,618...52,825,313
JBrowse link
G B3gnt3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 increases expression ISO methyleugenol results in increased expression of B3GNT3 mRNA CTD PMID:32234424 NCBI chr16:18,401,405...18,410,821
Ensembl chr16:18,401,405...18,410,766
JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 increases expression ISO methyleugenol results in increased expression of B4GALNT1 mRNA CTD PMID:32234424 NCBI chr 7:62,988,429...62,996,190
Ensembl chr 7:62,988,930...62,996,190
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase decreases expression ISO methyleugenol results in decreased expression of BAAT mRNA CTD PMID:32234424 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 decreases expression ISO methyleugenol results in decreased expression of BABAM2 mRNA CTD PMID:32234424 NCBI chr 6:24,369,021...24,833,335
Ensembl chr 6:24,369,022...24,833,951
JBrowse link
G Baiap2l2 BAR/IMD domain containing adaptor protein 2 like 2 increases expression ISO methyleugenol results in increased expression of BAIAP2L2 mRNA CTD PMID:32234424 NCBI chr 7:110,824,370...110,850,702
Ensembl chr 7:110,824,375...110,850,702
JBrowse link
G Bank1 B-cell scaffold protein with ankyrin repeats 1 decreases expression ISO methyleugenol results in decreased expression of BANK1 mRNA CTD PMID:32234424 NCBI chr 2:224,530,475...224,800,420
Ensembl chr 2:224,530,475...224,800,405
JBrowse link
G Batf3 basic leucine zipper ATF-like transcription factor 3 increases expression ISO methyleugenol results in increased expression of BATF3 mRNA CTD PMID:32234424 NCBI chr13:102,689,657...102,701,241
Ensembl chr13:102,689,657...102,701,139
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO methyleugenol results in increased expression of BAX mRNA CTD PMID:32234424 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 decreases expression ISO methyleugenol results in decreased expression of BBOX1 mRNA CTD PMID:32234424 NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458
JBrowse link
G Bbs9 Bardet-Biedl syndrome 9 decreases expression ISO methyleugenol results in decreased expression of BBS9 mRNA CTD PMID:32234424 NCBI chr 8:21,013,865...21,437,934
Ensembl chr 8:21,013,944...21,437,930
JBrowse link
G Bcas3 BCAS3, microtubule associated cell migration factor decreases expression ISO methyleugenol results in decreased expression of BCAS3 mRNA CTD PMID:32234424 NCBI chr10:70,213,710...70,673,080
Ensembl chr10:70,214,098...70,673,080
JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta decreases expression ISO methyleugenol results in decreased expression of BCKDHB mRNA CTD PMID:32234424 NCBI chr 8:84,845,264...85,027,812
Ensembl chr 8:84,845,264...85,027,812
JBrowse link
G Bcl2l15 BCL2-like 15 increases expression ISO methyleugenol results in increased expression of BCL2L15 mRNA CTD PMID:32234424 NCBI chr 2:191,338,959...191,344,078
Ensembl chr 2:191,338,959...191,344,078
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 decreases expression ISO methyleugenol results in decreased expression of BDH1 mRNA CTD PMID:32234424 NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671
JBrowse link
G Bdkrb2 bradykinin receptor B2 increases expression ISO methyleugenol results in increased expression of BDKRB2 mRNA CTD PMID:32234424 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 increases expression ISO methyleugenol results in increased expression of BHLHE41 mRNA CTD PMID:32234424 NCBI chr 4:178,833,085...178,838,685
Ensembl chr 4:178,834,271...178,838,468
JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase decreases expression ISO methyleugenol results in decreased expression of BHMT mRNA CTD PMID:32234424 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
JBrowse link
G Bmerb1 bMERB domain containing 1 decreases expression ISO methyleugenol results in decreased expression of BMERB1 mRNA CTD PMID:32234424 NCBI chr10:1,779,834...1,946,586
Ensembl chr10:1,779,835...1,946,575
JBrowse link
G Bmf Bcl2 modifying factor increases expression ISO methyleugenol results in increased expression of BMF mRNA CTD PMID:32234424 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B decreases expression ISO methyleugenol results in decreased expression of BMPR1B mRNA CTD PMID:32234424 NCBI chr 2:230,538,252...230,871,077
Ensembl chr 2:230,541,558...230,871,368
JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression EXP methyleugenol results in decreased expression of BRCA1 mRNA CTD PMID:21659616 PMID:26011634 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated decreases expression EXP methyleugenol results in decreased expression of BRCA2 mRNA CTD PMID:26011634 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 affects expression EXP methyleugenol affects the expression of BRCC3 mRNA CTD PMID:26011634 NCBI chr 9:1,986,942...1,989,484
Ensembl chr 9:1,986,575...1,991,080
JBrowse link
G Brinp1 BMP/retinoic acid inducible neural specific 1 decreases expression ISO methyleugenol results in decreased expression of BRINP1 mRNA CTD PMID:32234424 NCBI chr 5:82,348,501...82,550,506
Ensembl chr 5:82,348,930...82,493,150
JBrowse link
G Bsn bassoon (presynaptic cytomatrix protein) decreases expression ISO methyleugenol results in decreased expression of BSN mRNA CTD PMID:32234424 NCBI chr 8:108,784,849...108,875,819
Ensembl chr 8:108,788,542...108,875,819
JBrowse link
G Btbd16 BTB domain containing 16 decreases expression ISO methyleugenol results in decreased expression of BTBD16 mRNA CTD PMID:32234424 NCBI chr 1:185,334,971...185,389,518
Ensembl chr 1:185,335,725...185,389,517
JBrowse link
G Btbd9 BTB domain containing 9 decreases expression ISO methyleugenol results in decreased expression of BTBD9 mRNA CTD PMID:32234424 NCBI chr20:8,286,337...8,645,567
Ensembl chr20:8,288,711...8,643,960
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase increases expression EXP methyleugenol results in increased expression of BUB1 mRNA CTD PMID:26011634 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G C2cd4a C2 calcium-dependent domain containing 4A increases expression ISO methyleugenol results in increased expression of C2CD4A mRNA CTD PMID:32234424 NCBI chr 8:68,467,017...68,470,033
Ensembl chr 8:68,466,664...68,470,031
JBrowse link
G C4bpa complement component 4 binding protein, alpha decreases expression ISO methyleugenol results in decreased expression of C4BPA mRNA CTD PMID:32234424 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205
JBrowse link
G C4bpb complement component 4 binding protein, beta decreases expression ISO methyleugenol results in decreased expression of C4BPB mRNA CTD PMID:32234424 NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817
JBrowse link
G C5 complement C5 decreases expression ISO methyleugenol results in decreased expression of C5 mRNA CTD PMID:32234424 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
JBrowse link
G C6 complement C6 decreases expression ISO methyleugenol results in decreased expression of C6 mRNA CTD PMID:32234424 NCBI chr 2:53,846,027...53,921,279
Ensembl chr 2:53,851,985...53,921,275
JBrowse link
G C8a complement C8 alpha chain decreases expression ISO methyleugenol results in decreased expression of C8A mRNA CTD PMID:32234424 NCBI chr 5:119,583,168...119,637,675
Ensembl chr 5:119,583,174...119,637,754
JBrowse link
G C8b complement C8 beta chain decreases expression ISO methyleugenol results in decreased expression of C8B mRNA CTD PMID:32234424 NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565
JBrowse link
G C8g complement C8 gamma chain decreases expression ISO methyleugenol results in decreased expression of C8G mRNA CTD PMID:32234424 NCBI chr 3:8,320,495...8,323,495
Ensembl chr 3:8,305,920...8,323,495
JBrowse link
G C9 complement C9 decreases expression ISO methyleugenol results in decreased expression of C9 mRNA CTD PMID:32234424 NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338
JBrowse link
G Ca12 carbonic anhydrase 12 increases expression ISO methyleugenol results in increased expression of CA12 mRNA CTD PMID:32234424 NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440
JBrowse link
G Ca3 carbonic anhydrase 3 decreases expression ISO methyleugenol results in decreased expression of CA3 mRNA CTD PMID:32234424 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
JBrowse link
G Ca9 carbonic anhydrase 9 decreases expression ISO methyleugenol results in decreased expression of CA9 mRNA CTD PMID:32234424 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D decreases expression ISO methyleugenol results in decreased expression of CACNA1D mRNA CTD PMID:32234424 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 decreases expression ISO methyleugenol results in decreased expression of CACNA2D1 mRNA CTD PMID:32234424 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969
JBrowse link
G Cacna2d3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 decreases expression ISO methyleugenol results in decreased expression of CACNA2D3 mRNA CTD PMID:32234424 NCBI chr16:4,098,439...4,912,498
Ensembl chr16:4,098,445...4,912,351
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 increases expression ISO methyleugenol results in increased expression of CACNB3 mRNA CTD PMID:32234424 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074
JBrowse link
G Cadm2 cell adhesion molecule 2 decreases expression ISO methyleugenol results in decreased expression of CADM2 mRNA CTD PMID:32234424 NCBI chr11:4,548,367...5,525,420
Ensembl chr11:4,555,159...5,525,400
JBrowse link
G Cadps2 calcium dependent secretion activator 2 decreases expression ISO methyleugenol results in decreased expression of CADPS2 mRNA CTD PMID:32234424 NCBI chr 4:51,780,415...52,309,641
Ensembl chr 4:51,781,053...52,309,829
JBrowse link
G Calb2 calbindin 2 increases expression ISO methyleugenol results in increased expression of CALB2 mRNA CTD PMID:32234424 NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438
JBrowse link
G Calml4 calmodulin-like 4 decreases expression ISO methyleugenol results in decreased expression of CALML4 mRNA CTD PMID:32234424 NCBI chr 8:63,323,426...63,335,234
Ensembl chr 8:63,323,351...63,335,234
JBrowse link
G Caln1 calneuron 1 decreases expression ISO methyleugenol results in decreased expression of CALN1 mRNA CTD PMID:32234424 NCBI chr12:25,811,743...26,303,670
Ensembl chr12:25,819,628...26,303,344
JBrowse link
G Camk1d calcium/calmodulin-dependent protein kinase ID decreases expression ISO methyleugenol results in decreased expression of CAMK1D mRNA CTD PMID:32234424 NCBI chr17:72,581,899...72,982,704
Ensembl chr17:72,581,979...72,980,556
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV decreases expression ISO methyleugenol results in decreased expression of CAMK4 mRNA CTD PMID:32234424 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487
JBrowse link
G Carmil3 capping protein regulator and myosin 1 linker 3 decreases expression ISO methyleugenol results in decreased expression of CARMIL3 mRNA CTD PMID:32234424 NCBI chr15:28,978,440...28,995,865
Ensembl chr15:28,979,007...28,996,225
JBrowse link
G Casp16 caspase 16 decreases expression ISO methyleugenol results in decreased expression of CASP16P mRNA CTD PMID:32234424 NCBI chr10:12,586,009...12,592,023 JBrowse link
G Casp3 caspase 3 increases cleavage
increases activity
EXP
ISO
methyleugenol results in increased cleavage of CASP3 protein
methyleugenol results in increased activity of CASP3 protein
CTD PMID:26011634 PMID:28818686 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase decreases expression ISO methyleugenol results in decreased expression of CAT mRNA CTD PMID:32234424 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Catsper3 cation channel, sperm associated 3 decreases expression ISO methyleugenol results in decreased expression of CATSPER3 mRNA CTD PMID:32234424 NCBI chr17:8,810,122...8,840,881
Ensembl chr17:8,815,561...8,840,864
JBrowse link
G Catspere catsper channel auxiliary subunit epsilon decreases expression ISO methyleugenol results in decreased expression of CATSPERE mRNA CTD PMID:32234424 NCBI chr13:89,799,669...89,954,723 JBrowse link
G Cbarp CACN subunit beta associated regulatory protein decreases expression ISO methyleugenol results in decreased expression of CBARP mRNA CTD PMID:32234424 NCBI chr 7:9,566,637...9,575,204
Ensembl chr 7:9,566,364...9,575,204
JBrowse link
G Cbr3 carbonyl reductase 3 increases expression ISO methyleugenol results in increased expression of CBR3 mRNA CTD PMID:32234424 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
JBrowse link
G Cbx5 chromobox 5 increases expression EXP methyleugenol results in increased expression of CBX5 protein CTD PMID:23411599 NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022
JBrowse link
G Ccbe1 collagen and calcium binding EGF domains 1 decreases expression ISO methyleugenol results in decreased expression of CCBE1 mRNA CTD PMID:32234424 NCBI chr18:59,579,851...59,823,977 JBrowse link
G Ccdc141 coiled-coil domain containing 141 decreases expression ISO methyleugenol results in decreased expression of CCDC141 mRNA CTD PMID:32234424 NCBI chr 3:61,948,614...62,109,968
Ensembl chr 3:61,948,646...62,110,079
JBrowse link
G Ccdc146 coiled-coil domain containing 146 decreases expression ISO methyleugenol results in decreased expression of CCDC146 mRNA CTD PMID:32234424 NCBI chr 4:13,662,766...13,811,619
Ensembl chr 4:13,662,766...13,811,608
JBrowse link
G Ccdc170 coiled-coil domain containing 170 decreases expression ISO methyleugenol results in decreased expression of CCDC170 mRNA CTD PMID:32234424 NCBI chr 1:40,945,607...41,050,010
Ensembl chr 1:40,945,961...41,085,040
JBrowse link
G Ccdc171 coiled-coil domain containing 171 decreases expression ISO methyleugenol results in decreased expression of CCDC171 mRNA CTD PMID:32234424 NCBI chr 5:97,919,965...98,403,853 JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO methyleugenol results in decreased expression of CCN2 mRNA CTD PMID:32234424 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO methyleugenol results in decreased expression of CCNB1 mRNA CTD PMID:32234424 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccng1 cyclin G1 increases expression ISO methyleugenol results in increased expression of CCNG1 mRNA CTD PMID:15618236 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Ccrl2 C-C motif chemokine receptor like 2 increases expression ISO methyleugenol results in increased expression of CCRL2 mRNA CTD PMID:32234424 NCBI chr 8:111,034,279...111,036,914
Ensembl chr 8:111,034,279...111,036,664
JBrowse link
G Ccser1 coiled-coil serine-rich protein 1 decreases expression ISO methyleugenol results in decreased expression of CCSER1 mRNA CTD PMID:32234424 NCBI chr 4:90,153,873...91,391,441
Ensembl chr 4:90,292,780...91,388,786
JBrowse link
G Cd22 CD22 molecule increases expression ISO methyleugenol results in increased expression of CD22 mRNA CTD PMID:32234424 NCBI chr 1:86,116,376...86,132,782
Ensembl chr 1:86,117,459...86,132,322
JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression ISO methyleugenol results in increased expression of CD44 mRNA CTD PMID:32234424 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd9 CD9 molecule increases expression ISO methyleugenol results in increased expression of CD9 mRNA CTD PMID:32234424 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
JBrowse link
G Cdc14a cell division cycle 14A decreases expression ISO methyleugenol results in decreased expression of CDC14A mRNA CTD PMID:32234424 NCBI chr 2:204,225,540...204,380,927
Ensembl chr 2:204,225,540...204,380,927
JBrowse link
G Cdc20b cell division cycle 20B decreases expression ISO methyleugenol results in decreased expression of CDC20B mRNA CTD PMID:32234424 NCBI chr 2:44,688,349...44,738,056 JBrowse link
G Cdca3 cell division cycle associated 3 decreases expression ISO methyleugenol results in decreased expression of CDCA3 mRNA CTD PMID:32234424 NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799
JBrowse link
G Cdh1 cadherin 1 decreases expression ISO methyleugenol results in decreased expression of CDH1 mRNA CTD PMID:32234424 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh12 cadherin 12 decreases expression ISO methyleugenol results in decreased expression of CDH12 mRNA CTD PMID:32234424 NCBI chr 2:70,474,679...71,705,369
Ensembl chr 2:70,475,043...71,700,572
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression EXP methyleugenol results in increased expression of CDK1 protein CTD PMID:23411599 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk14 cyclin-dependent kinase 14 decreases expression ISO methyleugenol results in decreased expression of CDK14 mRNA CTD PMID:32234424 NCBI chr 4:28,666,688...29,258,865
Ensembl chr 4:28,666,843...29,258,861
JBrowse link
G Cdk2ap2 cyclin-dependent kinase 2 associated protein 2 decreases expression ISO methyleugenol results in decreased expression of CDK2AP2 mRNA CTD PMID:32234424 NCBI chr 1:201,391,056...201,393,137
Ensembl chr 1:201,391,466...201,393,137
JBrowse link
G Cdkal1 CDK5 regulatory subunit associated protein 1-like 1 decreases expression ISO methyleugenol results in decreased expression of CDKAL1 mRNA CTD PMID:32234424 NCBI chr17:34,718,680...34,769,614
Ensembl chr17:34,718,687...35,407,524
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
increases phosphorylation
ISO
EXP
methyleugenol results in increased expression of CDKN1A mRNA
methyleugenol results in increased phosphorylation of CDKN1A protein
methyleugenol results in increased expression of CDKN1A mRNA; methyleugenol results in increased expression of CDKN1A protein
CTD PMID:15618236 PMID:23411599 PMID:26011634 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression
decreases expression
EXP methyleugenol results in increased expression of CDKN2A protein
methyleugenol results in decreased expression of CDKN2A mRNA
CTD PMID:23411599 PMID:26011634 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cdo1 cysteine dioxygenase type 1 decreases expression ISO methyleugenol results in decreased expression of CDO1 mRNA CTD PMID:32234424 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
JBrowse link
G Cdr2l cerebellar degeneration-related protein 2-like increases expression ISO methyleugenol results in increased expression of CDR2L mRNA CTD PMID:32234424 NCBI chr10:100,625,150...100,638,669
Ensembl chr10:100,624,607...100,638,666
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 increases expression ISO methyleugenol results in increased expression of CEACAM1 mRNA CTD PMID:32234424 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Ceacam20 CEA cell adhesion molecule 20 decreases expression ISO methyleugenol results in decreased expression of CEACAM20 mRNA CTD PMID:32234424 NCBI chr 1:79,622,077...79,643,782
Ensembl chr 1:79,622,077...79,643,782
JBrowse link
G Cemip cell migration inducing hyaluronidase 1 decreases expression ISO methyleugenol results in decreased expression of CEMIP mRNA CTD PMID:32234424 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415
JBrowse link
G Cenpa centromere protein A decreases expression ISO methyleugenol results in decreased expression of CENPA mRNA CTD PMID:32234424 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
JBrowse link
G Cenpe centromere protein E decreases expression ISO methyleugenol results in decreased expression of CENPE mRNA CTD PMID:32234424 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
JBrowse link
G Cep128 centrosomal protein 128 decreases expression ISO methyleugenol results in decreased expression of CEP128 mRNA CTD PMID:32234424 NCBI chr 6:109,951,009...110,328,686
Ensembl chr 6:109,951,061...110,328,713
JBrowse link
G Ces3a carboxylesterase 3a decreases expression ISO methyleugenol results in decreased expression of CES3 mRNA CTD PMID:32234424 NCBI chr19:32,992,386...33,000,562 JBrowse link
G Cfap20dc CFAP20 domain containing decreases expression ISO methyleugenol results in decreased expression of CFAP20DC mRNA CTD PMID:32234424 NCBI chr15:16,231,248...16,476,978
Ensembl chr15:16,231,299...16,476,977
JBrowse link
G Cfap52 cilia and flagella associated protein 52 decreases expression ISO methyleugenol results in decreased expression of CFAP52 mRNA CTD PMID:32234424 NCBI chr10:52,613,761...52,654,922
Ensembl chr10:52,613,762...52,654,934
JBrowse link
G Cfb complement factor B decreases expression ISO methyleugenol results in decreased expression of CFB mRNA CTD PMID:32234424 NCBI chr20:3,970,643...3,976,510 JBrowse link
G Cfhr1 complement factor H-related 1 decreases expression ISO methyleugenol results in decreased expression of CFHR1 mRNA CTD PMID:32234424 NCBI chr13:51,395,583...51,410,571
Ensembl chr13:51,369,211...51,410,592
JBrowse link
G Cfhr2 complement factor H-related 2 decreases expression ISO methyleugenol results in decreased expression of CFHR4 mRNA CTD PMID:32234424 NCBI chr13:51,175,824...51,247,924
Ensembl chr13:51,175,841...51,247,495
JBrowse link
G Cfhr4 complement factor H-related 4 decreases expression ISO methyleugenol results in decreased expression of CFHR3 mRNA CTD PMID:32234424 NCBI chr13:51,422,592...51,491,476
Ensembl chr13:51,422,592...51,491,502
JBrowse link
G Chek1 checkpoint kinase 1 affects expression EXP methyleugenol affects the expression of CHEK1 mRNA CTD PMID:26011634 NCBI chr 8:36,420,565...36,443,477 JBrowse link
G Chek2 checkpoint kinase 2 decreases expression EXP methyleugenol results in decreased expression of CHEK2 mRNA CTD PMID:26011634 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Chn2 chimerin 2 decreases expression ISO methyleugenol results in decreased expression of CHN2 mRNA CTD PMID:32234424 NCBI chr 4:83,148,616...83,407,711
Ensembl chr 4:83,147,983...83,407,709
JBrowse link
G Cideb cell death-inducing DFFA-like effector b decreases expression ISO methyleugenol results in decreased expression of CIDEB mRNA CTD PMID:32234424 NCBI chr15:29,252,203...29,256,759
Ensembl chr15:29,252,213...29,256,605
JBrowse link
G Cish cytokine inducible SH2-containing protein decreases expression ISO methyleugenol results in decreased expression of CISH mRNA CTD PMID:15618236 NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250
JBrowse link
G Clcnka chloride voltage-gated channel Ka decreases expression ISO methyleugenol results in decreased expression of CLCNKA mRNA CTD PMID:32234424 NCBI chr 5:153,691,208...153,706,295
Ensembl chr 5:153,691,209...153,706,148
JBrowse link
G Cldn14 claudin 14 decreases expression ISO methyleugenol results in decreased expression of CLDN14 mRNA CTD PMID:32234424 NCBI chr11:33,232,281...33,329,440
Ensembl chr11:33,232,220...33,329,171
JBrowse link
G Cldn16 claudin 16 decreases expression ISO methyleugenol results in decreased expression of CLDN16 mRNA CTD PMID:32234424 NCBI chr11:74,290,298...74,309,588
Ensembl chr11:74,290,298...74,309,588
JBrowse link
G Clrn3 clarin 3 decreases expression ISO methyleugenol results in decreased expression of CLRN3 mRNA CTD PMID:32234424 NCBI chr 1:190,319,025...190,334,648
Ensembl chr 1:190,319,026...190,334,648
JBrowse link
G Clybl citramalyl-CoA lyase decreases expression ISO methyleugenol results in decreased expression of CLYBL mRNA CTD PMID:32234424 NCBI chr15:99,283,644...99,505,697
Ensembl chr15:99,283,650...99,505,695
JBrowse link
G Cmss1 cms1 ribosomal small subunit homolog decreases expression ISO methyleugenol results in decreased expression of CMSS1 mRNA CTD PMID:32234424 NCBI chr11:42,934,390...43,232,624
Ensembl chr11:42,934,440...43,232,624
JBrowse link
G Cnga1 cyclic nucleotide gated channel subunit alpha 1 decreases expression ISO methyleugenol results in decreased expression of CNGA1 mRNA CTD PMID:32234424 NCBI chr14:35,566,947...35,605,065
Ensembl chr14:35,567,125...35,605,065
JBrowse link
G Cnksr2 connector enhancer of kinase suppressor of Ras 2 decreases expression ISO methyleugenol results in decreased expression of CNKSR2 mRNA CTD PMID:32234424 NCBI chr  X:36,908,135...37,148,337
Ensembl chr  X:36,907,850...37,150,555
JBrowse link
G Cntn1 contactin 1 decreases expression ISO methyleugenol results in decreased expression of CNTN1 mRNA CTD PMID:32234424 NCBI chr 7:123,263,146...123,560,896
Ensembl chr 7:123,372,792...123,558,541
JBrowse link
G Cntn5 contactin 5 decreases expression ISO methyleugenol results in decreased expression of CNTN5 mRNA CTD PMID:32234424 NCBI chr 8:6,735,715...7,967,727
Ensembl chr 8:6,738,239...7,967,957
JBrowse link
G Cobl cordon-bleu WH2 repeat protein decreases expression ISO methyleugenol results in decreased expression of COBL mRNA CTD PMID:32234424 NCBI chr14:86,828,137...87,060,682
Ensembl chr14:86,828,139...87,060,800
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain decreases expression ISO methyleugenol results in decreased expression of COL18A1 mRNA CTD PMID:32234424 NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593
JBrowse link
G Col5a2 collagen type V alpha 2 chain decreases expression ISO methyleugenol results in decreased expression of COL5A2 mRNA CTD PMID:32234424 NCBI chr 9:47,448,736...47,598,396
Ensembl chr 9:47,448,736...47,598,154
JBrowse link
G Col8a1 collagen type VIII alpha 1 chain decreases expression ISO methyleugenol results in decreased expression of COL8A1 mRNA CTD PMID:32234424 NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424
JBrowse link
G Commd1 copper metabolism domain containing 1 decreases expression ISO methyleugenol results in decreased expression of COMMD1 mRNA CTD PMID:32234424 NCBI chr14:96,880,463...96,984,494
Ensembl chr14:96,880,463...96,984,501
JBrowse link
G Commd10 COMM domain containing 10 decreases expression ISO