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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:metamizole
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Accession:CHEBI:62088 term browser browse the term
Definition:A pyrazole that is antiipyrine substituted at C-4 by a methyl(sulfomethyl)amino group, the sodium salt of which, metamizole sodium, was widely used as a powerful analgesic and antipyretic, but withdrawn from many markets from the 1970s due to a risk of causing risk of causing agranulocytosis.
Synonyms:exact_synonym: [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonic acid
 related_synonym: (antipyrinylmethylamino)methanesulfonic acid;   Formula=C13H17N3O4S;   InChI=1S/C13H17N3O4S/c1-10-12(14(2)9-21(18,19)20)13(17)16(15(10)3)11-7-5-4-6-8-11/h4-8H,9H2,1-3H3,(H,18,19,20);   InChIKey=LVWZTYCIRDMTEY-UHFFFAOYSA-N;   N-(2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)-N-methylaminomethanesulfonic acid;   SMILES=CN(CS(O)(=O)=O)c1c(C)n(C)n(-c2ccccc2)c1=O;   [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulfonic acid;   metamizol;   metamizolum
 xref: CAS:50567-35-6;   DrugBank:DB04817;   Drug_Central:4659;   HMDB:HMDB0254502;   KEGG:D08188;   LINCS:LSM-5839;   PMID:11048407;   PMID:24724493;   PMID:29772595;   PMID:31435718;   PMID:32238269;   PMID:32588405;   PMID:33247375;   PMID:33675325;   PMID:33823317;   PMID:34038591;   PMID:34181748;   PMID:34273099;   PMID:34648192;   PMID:34726072;   PMID:35043434;   PMID:35138735;   PMID:35156383;   PMID:35275472;   PMID:35290991;   PMID:35416155;   PMID:35416465;   PMID:35433049;   PMID:35584441;   PMID:35670337;   PMID:35774740;   PMID:35774878;   PMID:35912424;   PMID:35933233;   Reaxys:327442;   Wikipedia:Metamizole
 cyclic_relationship: is_conjugate_acid_of CHEBI:62086



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Path 1
Term Annotations click to browse term
  CHEBI ontology 19860
    role 19832
      application 19675
        anti-inflammatory agent 16628
          metamizole 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19860
    subatomic particle 19858
      composite particle 19858
        hadron 19858
          baryon 19858
            nucleon 19858
              atomic nucleus 19858
                atom 19858
                  main group element atom 19804
                    p-block element atom 19804
                      carbon group element atom 19745
                        carbon atom 19741
                          organic molecular entity 19741
                            organic molecule 19692
                              organic cyclic compound 19503
                                organic heterocyclic compound 18875
                                  heteroarene 17153
                                    monocyclic heteroarene 14922
                                      azole 14437
                                        diazole 10534
                                          pyrazoles 2325
                                            pyrazolone 87
                                              antipyrine 3
                                                metamizole 0
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