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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:3beta-hydroxy-5alpha-cholest-8(14)-en-15-one
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Accession:CHEBI:61829 term browser browse the term
Definition:A 3beta-hydroxysteroid consisting of 3beta-hydroxy-5alpha-cholest-8(14)-ene having an additional oxo group at the 15-position.
Synonyms:related_synonym: (3beta,5alpha)-3-hydroxycholest-8(14)-en-15-one;   15-ketocholestene;   15-oxo-5alpha-cholest-8(14)-en-3beta-ol;   5alpha-cholest-8(14)-en-3-beta-ol-15-one;   Formula=C27H44O2;   InChI=1S/C27H44O2/c1-17(2)7-6-8-18(3)23-16-24(29)25-21-10-9-19-15-20(28)11-13-26(19,4)22(21)12-14-27(23,25)5/h17-20,22-23,28H,6-16H2,1-5H3/t18-,19+,20+,22+,23-,26+,27-/m1/s1;   InChIKey=LINVVMHRTUSXHL-GGVPDPBRSA-N;   SMILES=[H][C@@]12CCC3=C4C(=O)C[C@]([H])([C@H](C)CCCC(C)C)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CC[C@H](O)C2;   colestolona;   colestolone;   colestolonum
 xref: CAS:50673-97-7;   LIPID_MAPS_instance:LMST01010269
 xref_mesh: MESH:C015073
 xref: PMID:1542104;   PMID:16341241;   PMID:8033288;   PMID:9779586;   Reaxys:3219975


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3beta-hydroxy-5alpha-cholest-8(14)-en-15-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases activity ISO cholest-8(14)-en-3-ol-15-one results in decreased activity of HMGCR protein CTD PMID:7751816 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    chemical entity 19840
      molecular entity 19809
        polyatomic entity 19767
          heteroatomic molecular entity 19723
            hydroxides 19300
              organic hydroxy compound 18928
                alcohol 15673
                  secondary alcohol 7749
                    3beta-hydroxy steroid 2527
                      3beta-hydroxy-5alpha-cholest-8(14)-en-15-one 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      carbon group element atom 19708
                        carbon atom 19734
                          organic molecular entity 19705
                            organic molecule 19658
                              organic cyclic compound 19471
                                organic polycyclic compound 17244
                                  steroid 14672
                                    hydroxy steroid 14419
                                      3-hydroxy steroid 12757
                                        3beta-hydroxy steroid 2527
                                          3beta-hydroxy-5alpha-cholest-8(14)-en-15-one 1
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