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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:amino cyclitol
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Accession:CHEBI:61689 term browser browse the term
Definition:Any cyclitol having one or more alcoholic hydroxy groups replaced by substituted or unsubstituted amino groups.
Synonyms:related_synonym: amino cyclitols;   aminocyclitol;   aminocyclitols


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isepamicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pgd phosphogluconate dehydrogenase decreases activity EXP isepamicin results in decreased activity of PGD protein CTD PMID:15558954 NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel increases expression ISO isepamicin results in increased expression of PKD2 protein mutant form CTD PMID:15001556 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825 		JBrowse link
netilmycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pgd phosphogluconate dehydrogenase decreases activity EXP Netilmicin results in decreased activity of PGD protein CTD PMID:15558954 NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
paromomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase increases expression ISO Paromomycin results in increased expression of ATM protein mutant form CTD PMID:15498871 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
streptomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxb9 homeo box B9 multiple interactions ISO [Penicillins co-treated with Streptomycin] results in increased expression of HOXB9 mRNA CTD PMID:31711903 NCBI chr10:81,237,312...81,240,818
Ensembl chr10:81,237,312...81,240,818 		JBrowse link
G Pax3 paired box 3 multiple interactions ISO [Penicillins co-treated with Streptomycin] results in increased expression of PAX3 mRNA CTD PMID:31711903 NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042 		JBrowse link
G Tcf15 transcription factor 15 multiple interactions ISO [Penicillins co-treated with Streptomycin] results in increased expression of TCF15 mRNA CTD PMID:31711903 NCBI chr 3:140,638,984...140,644,766
Ensembl chr 3:140,638,984...140,644,766 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Streptomycin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:17699551 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Uncx UNC homeobox multiple interactions ISO [Penicillins co-treated with Streptomycin] results in increased expression of UNCX mRNA CTD PMID:31711903 NCBI chr12:15,092,779...15,097,300
Ensembl chr12:15,092,784...15,097,300 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19853
    chemical entity 19851
      molecular entity 19851
        polyatomic entity 19808
          heteroatomic molecular entity 19763
            hydroxides 19325
              organic hydroxy compound 18956
                polyol 11712
                  cyclitol 7493
                    amino cyclitol 8
                      (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2R,3R,6S)-3-amino-6-[(1R)-1-aminoethyl]-2-oxanyl]oxy]-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2R,3R,6S)-3-amino-6-(aminomethyl)-2-oxanyl]oxy]-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2R,3R,6S)-3-amino-6-[(1R)-1-(methylamino)ethyl]-2-oxanyl]oxy]-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol 0
                      (2R,3R,4R,5S,6R)-5-[[(2R,3R,4R,5S,6R)-5-[[(2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-1-cyclohex-2-enyl]amino]-2-oxanyl]oxy]-3,4-dihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-6-(hydroxymethyl)oxane-2,3,4-triol 0
                      (2R,3R,4S,5S,6S)-2-[[(3S,4R,6S,7R,8aS)-7-amino-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy-4-hydroxy-3-(methylamino)-2,3,4,4a,6,7,8,8a-octahydropyrano[3,2-b]pyran-2-yl]oxy]-5-amino-6-(hydroxymethyl)oxane-3,4-diol 0
                      (2R,4S,5S)-2-[[(2R,6S,8aS)-7-amino-6-[(2R,4R)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy-4-hydroxy-3-(methylamino)-2,3,4,4a,6,7,8,8a-octahydropyrano[3,2-b]pyran-2-yl]oxy]-5-amino-6-(hydroxymethyl)oxane-3,4-diol 0
                      (2S,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2R,3R,6S)-3-amino-6-[1-(methylamino)ethyl]-2-oxanyl]oxy]-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol 0
                      (2S,3R,4S,5S)-2-[(1R,2S,3S,4R,6S)-4,6-diamino-3-[[3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol 0
                      1-amino-1-deoxy-scyllo-inositol 0
                      2-Amino-5-epi-valiolone 0
                      2-[(1S,2S,3R,4S,5S,6R)-3-(diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-hydroxy-4-(hydroxymethyl)-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine 0
                      2-deoxy-scyllo-inosamine 0
                      2-deoxystreptamine + 0
                      2-deoxystreptamine derivative + 0
                      2-deoxystreptidine 0
                      2-epi-Streptamine 0
                      3''-Amino-3''-deoxygentamicin A2 0
                      3''-Oxogentamicin A2 0
                      3-Keto-scyllo-inosamine 0
                      3-O-Demethylfortimicin A 0
                      4'-Oxonebramine 0
                      5-amino-2-(aminomethyl)-6-[4,6-diamino-2-[[(2S,3S,4S)-4-[(3-amino-4,5-dihydroxy-2-oxanyl)methoxymethyl]-3-hydroxy-2-oxolanyl]oxy]-3-hydroxycyclohexyl]oxyoxane-3,4-diol 0
                      6'-Oxo-G418 0
                      6'-Oxogentamicin X2 0
                      6'-Oxolividamine 0
                      A-396-I 0
                      AB-74 0
                      AHB-6-Methylneamine 0
                      AHB-Gentamine-C1a 0
                      Acarviosin 0
                      Acarviostatin I03 0
                      Acarviostatin II03 0
                      Acarviostatin II13 0
                      Acarviostatin III0(-1) 0
                      Acarviostatin III03 0
                      Acarviostatin III23 0
                      Acarviostatin IV03 0
                      Actinamine 0
                      Amylostatin XG 0
                      Apramycin sulfate 0
                      Ashimycin A 0
                      Bluensidine 0
                      Boholmycin 0
                      CKD-711 0
                      CKD-711a 0
                      Destomycin C 0
                      Destomysin 0
                      Epivaliolamine 0
                      Fortimicin C 0
                      Fortimicin D 0
                      Fortimicin KE 0
                      Fortimicin KL1 0
                      G-367 S1 0
                      G-52 0
                      Garamine 0
                      Geneticin sulfate 0
                      Gentamicin B 0
                      Gentamicin C2a 0
                      HS44 0
                      Inosamycin A 0
                      Inosamycin B 0
                      Inosamycin C 0
                      Inosamycin D 0
                      Inosamycin E 0
                      Kasugamycin hydrochloride 0
                      LSM-6702 0
                      LSM-6706 0
                      Lividamine 0
                      N-demethylstreptomycin 0
                      N3'-Acetylapramycin 0
                      N3'-Acetylneomycin 0
                      Nebramine 0
                      Neomycin K 0
                      Oligostatin C 0
                      Oligostatin D 0
                      Oligostatin E 0
                      Penicillin-Streptomycin Solution (100X) 0
                      Rhodostreptomycin A 0
                      Rhodostreptomycin B 0
                      S-11-A 0
                      SU-1 0
                      SU-2 0
                      SU-3 0
                      Sannamycin C 0
                      Streptomycin B 0
                      Trestatin A 0
                      Trestatin B 0
                      Trestatin C 0
                      Validamycin F 0
                      Validoxylamine G 0
                      Valiolamine 0
                      X-14847 0
                      bacteriohopanetetrol cyclitol ether 0
                      desoxymycin 0
                      mannostatin A 0
                      mannostatin B 0
                      neo-Inosamine-2 0
                      streptamine + 3
                      streptidine + 5
                      validamine + 0
                      validamine 7-phosphate 0
                      validoxylamine A 0
                      validoxylamine A 7'-phosphate 0
                      validoxylamine B 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19797
                    p-block element atom 19797
                      p-block molecular entity 19797
                        chalcogen molecular entity 19547
                          oxygen molecular entity 19520
                            hydroxides 19325
                              organic hydroxy compound 18956
                                polyol 11712
                                  cyclitol 7493
                                    amino cyclitol 8
                                      (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2R,3R,6S)-3-amino-6-[(1R)-1-aminoethyl]-2-oxanyl]oxy]-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2R,3R,6S)-3-amino-6-(aminomethyl)-2-oxanyl]oxy]-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2R,3R,6S)-3-amino-6-[(1R)-1-(methylamino)ethyl]-2-oxanyl]oxy]-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol 0
                                      (2R,3R,4R,5S,6R)-5-[[(2R,3R,4R,5S,6R)-5-[[(2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-1-cyclohex-2-enyl]amino]-2-oxanyl]oxy]-3,4-dihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-6-(hydroxymethyl)oxane-2,3,4-triol 0
                                      (2R,3R,4S,5S,6S)-2-[[(3S,4R,6S,7R,8aS)-7-amino-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy-4-hydroxy-3-(methylamino)-2,3,4,4a,6,7,8,8a-octahydropyrano[3,2-b]pyran-2-yl]oxy]-5-amino-6-(hydroxymethyl)oxane-3,4-diol 0
                                      (2R,4S,5S)-2-[[(2R,6S,8aS)-7-amino-6-[(2R,4R)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy-4-hydroxy-3-(methylamino)-2,3,4,4a,6,7,8,8a-octahydropyrano[3,2-b]pyran-2-yl]oxy]-5-amino-6-(hydroxymethyl)oxane-3,4-diol 0
                                      (2S,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2R,3R,6S)-3-amino-6-[1-(methylamino)ethyl]-2-oxanyl]oxy]-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol 0
                                      (2S,3R,4S,5S)-2-[(1R,2S,3S,4R,6S)-4,6-diamino-3-[[3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol 0
                                      1-amino-1-deoxy-scyllo-inositol 0
                                      2-Amino-5-epi-valiolone 0
                                      2-[(1S,2S,3R,4S,5S,6R)-3-(diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-hydroxy-4-(hydroxymethyl)-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine 0
                                      2-deoxy-scyllo-inosamine 0
                                      2-deoxystreptamine + 0
                                      2-deoxystreptamine derivative + 0
                                      2-deoxystreptidine 0
                                      2-epi-Streptamine 0
                                      3''-Amino-3''-deoxygentamicin A2 0
                                      3''-Oxogentamicin A2 0
                                      3-Keto-scyllo-inosamine 0
                                      3-O-Demethylfortimicin A 0
                                      4'-Oxonebramine 0
                                      5-amino-2-(aminomethyl)-6-[4,6-diamino-2-[[(2S,3S,4S)-4-[(3-amino-4,5-dihydroxy-2-oxanyl)methoxymethyl]-3-hydroxy-2-oxolanyl]oxy]-3-hydroxycyclohexyl]oxyoxane-3,4-diol 0
                                      6'-Oxo-G418 0
                                      6'-Oxogentamicin X2 0
                                      6'-Oxolividamine 0
                                      A-396-I 0
                                      AB-74 0
                                      AHB-6-Methylneamine 0
                                      AHB-Gentamine-C1a 0
                                      Acarviosin 0
                                      Acarviostatin I03 0
                                      Acarviostatin II03 0
                                      Acarviostatin II13 0
                                      Acarviostatin III0(-1) 0
                                      Acarviostatin III03 0
                                      Acarviostatin III23 0
                                      Acarviostatin IV03 0
                                      Actinamine 0
                                      Amylostatin XG 0
                                      Apramycin sulfate 0
                                      Ashimycin A 0
                                      Bluensidine 0
                                      Boholmycin 0
                                      CKD-711 0
                                      CKD-711a 0
                                      Destomycin C 0
                                      Destomysin 0
                                      Epivaliolamine 0
                                      Fortimicin C 0
                                      Fortimicin D 0
                                      Fortimicin KE 0
                                      Fortimicin KL1 0
                                      G-367 S1 0
                                      G-52 0
                                      Garamine 0
                                      Geneticin sulfate 0
                                      Gentamicin B 0
                                      Gentamicin C2a 0
                                      HS44 0
                                      Inosamycin A 0
                                      Inosamycin B 0
                                      Inosamycin C 0
                                      Inosamycin D 0
                                      Inosamycin E 0
                                      Kasugamycin hydrochloride 0
                                      LSM-6702 0
                                      LSM-6706 0
                                      Lividamine 0
                                      N-demethylstreptomycin 0
                                      N3'-Acetylapramycin 0
                                      N3'-Acetylneomycin 0
                                      Nebramine 0
                                      Neomycin K 0
                                      Oligostatin C 0
                                      Oligostatin D 0
                                      Oligostatin E 0
                                      Penicillin-Streptomycin Solution (100X) 0
                                      Rhodostreptomycin A 0
                                      Rhodostreptomycin B 0
                                      S-11-A 0
                                      SU-1 0
                                      SU-2 0
                                      SU-3 0
                                      Sannamycin C 0
                                      Streptomycin B 0
                                      Trestatin A 0
                                      Trestatin B 0
                                      Trestatin C 0
                                      Validamycin F 0
                                      Validoxylamine G 0
                                      Valiolamine 0
                                      X-14847 0
                                      bacteriohopanetetrol cyclitol ether 0
                                      desoxymycin 0
                                      mannostatin A 0
                                      mannostatin B 0
                                      neo-Inosamine-2 0
                                      streptamine + 3
                                      streptidine + 5
                                      validamine + 0
                                      validamine 7-phosphate 0
                                      validoxylamine A 0
                                      validoxylamine A 7'-phosphate 0
                                      validoxylamine B 0
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