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ONTOLOGY REPORT - ANNOTATIONS


Term:levobupivacaine
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Accession:CHEBI:6149 term browser browse the term
Definition:The (S)-(-)-enantiomer of bupivacaine.
Synonyms:exact_synonym: (2S)-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
 related_synonym: (-)-bupivacaine;   (S)-1-butyl-2',6'-pipecoloxylidide;   (S)-bupivacaine;   Formula=C18H28N2O;   InChI=1S/C18H28N2O/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21)/t16-/m0/s1;   InChIKey=LEBVLXFERQHONN-INIZCTEOSA-N;   L-(-)-1-Butyl-2',6'-pipecoloxylidide;   L-(-)-bupivacaine;   SMILES=CCCCN1CCCC[C@H]1C(=O)Nc1c(C)cccc1C
 xref: CAS:27262-47-1;   DrugBank:DB01002;   Drug_Central:4;   HMDB:HMDB0015137;   KEGG:C07887;   KEGG:D08116;   Reaxys:5382240;   Wikipedia:Levobupivacaine
 cyclic_relationship: is_conjugate_base_of CHEBI:77458;   is_enantiomer_of CHEBI:60790


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bupivacaine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 JBrowse link 12 19,074,288 19,114,491 RGD:6480464
G Entpd4 ectonucleoside triphosphate diphosphohydrolase 4 JBrowse link 15 51,222,954 51,250,787 RGD:6480464
G Hpgds hematopoietic prostaglandin D synthase JBrowse link 4 95,945,356 95,970,666 RGD:6480464
G Hrh1 histamine receptor H 1 JBrowse link 4 146,374,596 146,458,148 RGD:6480464
G Itgam integrin subunit alpha M JBrowse link 1 199,495,312 199,545,738 RGD:6480464
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 JBrowse link 11 32,498,260 32,511,202 RGD:6480464
G Kcnk9 potassium two pore domain channel subfamily K member 9 JBrowse link 7 113,894,918 113,938,397 RGD:6480464
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:6480464
G Myf5 myogenic factor 5 JBrowse link 7 49,729,533 49,732,974 RGD:6480464
G Myod1 myogenic differentiation 1 JBrowse link 1 102,396,538 102,399,248 RGD:6480464
G Myog myogenin JBrowse link 13 51,126,459 51,129,048 RGD:6480464
G Prkcb protein kinase C, beta JBrowse link 1 192,233,569 192,575,339 RGD:6480464
G Ptgdr prostaglandin D2 receptor JBrowse link 15 19,195,606 19,196,508 RGD:6480464
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Slc6a2 solute carrier family 6 member 2 JBrowse link 19 15,391,682 15,431,274 RGD:6480464
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:6480464
G Xrcc6 X-ray repair cross complementing 6 JBrowse link 7 123,259,881 123,280,613 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19779
    role 19727
      chemical role 19258
        emulsifier 3784
          surfactant 3784
            amphiphile 22
              levobupivacaine 22
                bupivacaine 22
Path 2
Term Annotations click to browse term
  CHEBI ontology 19779
    subatomic particle 19777
      composite particle 19777
        hadron 19777
          baryon 19777
            nucleon 19777
              atomic nucleus 19777
                atom 19777
                  main group element atom 19664
                    p-block element atom 19664
                      carbon group element atom 19559
                        carbon atom 19548
                          organic molecular entity 19548
                            organic group 18463
                              organic divalent group 18456
                                organodiyl group 18456
                                  carbonyl group 18356
                                    carbonyl compound 18356
                                      carboxylic acid 18027
                                        carboacyl group 17185
                                          univalent carboacyl group 17185
                                            carbamoyl group 16924
                                              carboxamide 16924
                                                monocarboxylic acid amide 14576
                                                  piperidinecarboxamide 30
                                                    1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide 22
                                                      levobupivacaine 22
                                                        bupivacaine 22
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.