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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:kuwanone H
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Accession:CHEBI:6147 term browser browse the term
Definition:A tetrahydroxyflavone isolated from the plant species of the genus Morus.
Synonyms:exact_synonym: 8-{(1R,2S,3S)-2-[2,4-dihydroxy-3-(3-methylbut-2-en-1-yl)benzoyl]-2',4'-dihydroxy-5-methyl[1,2,3,6-tetrahydro[1,1'-biphenyl]]-3-yl}-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylbut-2-en-1-yl)-4H-1-benzopyran-4-one
 related_synonym: Formula=C45H44O11;   InChI=1S/C45H44O11/c1-21(2)6-10-27-33(48)15-14-29(41(27)53)42(54)38-31(26-12-8-24(46)18-34(26)49)16-23(5)17-32(38)39-36(51)20-37(52)40-43(55)30(11-7-22(3)4)44(56-45(39)40)28-13-9-25(47)19-35(28)50/h6-9,12-15,17-20,31-32,38,46-53H,10-11,16H2,1-5H3/t31-,32-,38-/m0/s1;   InChIKey=DKBPTKFKCCNXNH-QXGWMLRCSA-N;   SMILES=CC(C)=CCc1c(O)ccc(C(=O)[C@H]2[C@@H](CC(C)=C[C@@H]2c2c(O)cc(O)c3c2oc(c(CC=C(C)C)c3=O)-c2ccc(O)cc2O)c2ccc(O)cc2O)c1O
 xref: CAS:76472-87-2;   HMDB:HMDB0030075;   KEGG:C10100;   KNApSAcK:C00001064
 xref_mesh: MESH:C095195
 xref: Reaxys:4640803


show annotations for term's descendants           Sort by:
 
kuwanone H term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grp gastrin releasing peptide multiple interactions EXP
ISO
kuwanon H inhibits the reaction [GRP protein binds to NMBR protein]
kuwanon H inhibits the reaction [GRP protein binds to GRPR protein]
CTD PMID:7646517 NCBI chr18:61,563,458...61,576,818
Ensembl chr18:61,563,053...61,576,818
JBrowse link
G Grpr gastrin releasing peptide receptor multiple interactions ISO kuwanon H binds to and results in decreased activity of GRPR protein; kuwanon H inhibits the reaction [GRP protein binds to GRPR protein] CTD PMID:7646517 NCBI chr  X:32,746,259...32,786,266
Ensembl chr  X:32,745,873...32,786,359
JBrowse link
G Nmbr neuromedin B receptor multiple interactions EXP kuwanon H inhibits the reaction [GRP protein binds to NMBR protein] CTD PMID:7646517 NCBI chr 1:8,933,744...8,945,850
Ensembl chr 1:8,933,831...8,944,987
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        biochemical role 19281
          metabolite 19262
            eukaryotic metabolite 18906
              plant metabolite 17359
                kuwanone H 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic molecule 19486
                              organic cyclic compound 19282
                                organic heterocyclic compound 18407
                                  oxacycle 17181
                                    benzopyran 10132
                                      1-benzopyran 9848
                                        flavonoid 6372
                                          flavones 4166
                                            hydroxyflavone 4154
                                              tetrahydroxyflavone 642
                                                kuwanone H 3
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