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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:kuwanone H
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Accession:CHEBI:6147 term browser browse the term
Definition:A tetrahydroxyflavone isolated from the plant species of the genus Morus.
Synonyms:exact_synonym: 8-{(1R,2S,3S)-2-[2,4-dihydroxy-3-(3-methylbut-2-en-1-yl)benzoyl]-2',4'-dihydroxy-5-methyl[1,2,3,6-tetrahydro[1,1'-biphenyl]]-3-yl}-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylbut-2-en-1-yl)-4H-1-benzopyran-4-one
 related_synonym: Formula=C45H44O11;   InChI=1S/C45H44O11/c1-21(2)6-10-27-33(48)15-14-29(41(27)53)42(54)38-31(26-12-8-24(46)18-34(26)49)16-23(5)17-32(38)39-36(51)20-37(52)40-43(55)30(11-7-22(3)4)44(56-45(39)40)28-13-9-25(47)19-35(28)50/h6-9,12-15,17-20,31-32,38,46-53H,10-11,16H2,1-5H3/t31-,32-,38-/m0/s1;   InChIKey=DKBPTKFKCCNXNH-QXGWMLRCSA-N;   SMILES=CC(C)=CCc1c(O)ccc(C(=O)[C@H]2[C@@H](CC(C)=C[C@@H]2c2c(O)cc(O)c3c2oc(c(CC=C(C)C)c3=O)-c2ccc(O)cc2O)c2ccc(O)cc2O)c1O
 xref: CAS:76472-87-2;   HMDB:HMDB0030075;   KEGG:C10100;   KNApSAcK:C00001064
 xref_mesh: MESH:C095195
 xref: Reaxys:4640803



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kuwanone H term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grp gastrin releasing peptide multiple interactions EXP
ISO
kuwanon H inhibits the reaction [GRP protein binds to NMBR protein]
kuwanon H inhibits the reaction [GRP protein binds to GRPR protein]
CTD PMID:7646517 NCBI chr18:59,388,679...59,402,061
Ensembl chr18:59,388,274...59,402,061
JBrowse link
G Grpr gastrin releasing peptide receptor multiple interactions ISO kuwanon H binds to and results in decreased activity of GRPR protein; kuwanon H inhibits the reaction [GRP protein binds to GRPR protein] CTD PMID:7646517 NCBI chr  X:30,998,425...31,038,442
Ensembl chr  X:30,998,416...31,038,442
JBrowse link
G Nmbr neuromedin B receptor multiple interactions EXP kuwanon H inhibits the reaction [GRP protein binds to NMBR protein] CTD PMID:7646517 NCBI chr 1:9,115,033...9,146,081
Ensembl chr 1:9,134,889...9,145,462
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19823
    role 19773
      biological role 19773
        biochemical role 19390
          metabolite 19367
            eukaryotic metabolite 19054
              plant metabolite 17458
                kuwanone H 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19823
    subatomic particle 19821
      composite particle 19821
        hadron 19821
          baryon 19821
            nucleon 19821
              atomic nucleus 19821
                atom 19821
                  main group element atom 19720
                    p-block element atom 19720
                      carbon group element atom 19643
                        carbon atom 19633
                          organic molecular entity 19633
                            organic molecule 19572
                              organic cyclic compound 19366
                                organic heterocyclic compound 18604
                                  oxacycle 17622
                                    benzopyran 10410
                                      1-benzopyran 10137
                                        flavonoid 6518
                                          flavones 4206
                                            hydroxyflavone 4194
                                              tetrahydroxyflavone 685
                                                kuwanone H 3
paths to the root