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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:methoxycinnamic acid
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Accession:CHEBI:61407 term browser browse the term
Definition:Any cinnamic acid carrying one or more methoxy substituents.
Synonyms:related_synonym: methoxycinnamic acids


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4-methoxycinnamic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase multiple interactions EXP 4-methoxycinnamic acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CAT] CTD PMID:22326950 NCBI chr 3:89,842,393...89,874,577 JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP 4-methoxycinnamic acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of GSR] CTD PMID:22326950 NCBI chr16:58,482,209...58,525,256 JBrowse link
sinapic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP sinapinic acid inhibits the reaction [Methotrexate results in increased expression of BAX protein] CTD PMID:33720507 NCBI chr 1:95,940,001...95,945,407 JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP sinapinic acid inhibits the reaction [Methotrexate results in decreased expression of BCL2 protein] CTD PMID:33720507 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Casp3 caspase 3 multiple interactions EXP sinapinic acid inhibits the reaction [Methotrexate affects the localization of CASP3 protein]; sinapinic acid inhibits the reaction [Methotrexate results in increased expression of CASP3 protein] CTD PMID:33720507 NCBI chr16:45,662,910...45,681,171 JBrowse link
G Cat catalase multiple interactions EXP sinapinic acid inhibits the reaction [Methotrexate results in decreased expression of CAT protein] CTD PMID:33720507 NCBI chr 3:89,842,393...89,874,577 JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity ISO sinapinic acid results in decreased activity of G6PD protein CTD PMID:25130191 NCBI chr  X:152,201,081...152,220,863 JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP sinapinic acid inhibits the reaction [Methotrexate results in increased expression of GPT protein] CTD PMID:33720507 NCBI chr 7:108,416,646...108,419,495 JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP sinapinic acid inhibits the reaction [Methotrexate results in decreased expression of HMOX1 protein] CTD PMID:33720507 NCBI chr19:13,466,287...13,474,082 JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
sinapinic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
sinapinic acid inhibits the reaction [Methotrexate results in increased expression of IL1B protein]
CTD PMID:18841975 PMID:33720507 NCBI chr 3:116,577,005...116,583,386 JBrowse link
G Mb myoglobin multiple interactions EXP sinapinic acid inhibits the reaction [Isoproterenol results in increased expression of MB protein] CTD PMID:32627257 NCBI chr 7:108,759,903...108,767,134 JBrowse link
G Mpo myeloperoxidase multiple interactions EXP sinapinic acid inhibits the reaction [Methotrexate results in increased expression of MPO protein] CTD PMID:33720507 NCBI chr10:72,594,458...72,608,862 JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO sinapinic acid inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein] CTD PMID:18841975 NCBI chr 2:224,016,214...224,132,135 JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO sinapinic acid inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased degradation of NFKBIA protein] CTD PMID:18841975 NCBI chr 6:72,858,713...72,861,941 JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO sinapinic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; sinapinic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:18841975 NCBI chr10:63,815,308...63,851,208 JBrowse link
G Ogdh oxoglutarate dehydrogenase multiple interactions EXP sinapinic acid inhibits the reaction [Isoproterenol results in decreased activity of OGDH protein] CTD PMID:32627257 NCBI chr14:81,150,021...81,217,479 JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity ISO sinapinic acid results in decreased activity of PGD protein CTD PMID:25130191 NCBI chr 5:159,582,746...159,598,945 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO sinapinic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; sinapinic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:18841975 NCBI chr13:62,164,080...62,169,770 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO sinapinic acid inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:18841975 NCBI chr 1:202,925,001...202,935,484 JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
sinapinic acid inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
sinapinic acid inhibits the reaction [Methotrexate results in increased expression of TNF protein]
CTD PMID:18841975 PMID:33720507 NCBI chr20:3,622,011...3,624,629 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19762
    chemical entity 19762
      atom 19760
        nonmetal atom 19641
          carbon atom 19560
            organic molecular entity 19560
              olefinic compound 15447
                cinnamic acids 2417
                  methoxycinnamic acid 19
                    (2E)-3-(4-\{[1-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-(sulfooxy)propan-2-yl]oxy\}-3-methoxyphenyl)prop-2-enoic acid 0
                    (2E)-3-(4-\{[3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-(sulfooxy)propan-2-yl]oxy\}-3-methoxyphenyl)prop-2-enoic acid 0
                    (2E)-3-[4-(\{1,3-dihydroxy-1-[3-methoxy-4-(sulfooxy)phenyl]propan-2-yl\}oxy)-3-methoxyphenyl]prop-2-enoic acid 0
                    3,4,5-trimethoxycinnamic acid 0
                    3,4-dimethoxycinnamic acid + 0
                    4-O-beta-D-glucosyl-trans-sinapic acid 0
                    4-methoxycinnamic acid + 2
                    5-hydroxyferulic acid + 0
                    poacic acid 0
                    sinapic acid + 18
Path 2
Term Annotations click to browse term
  CHEBI ontology 19762
    subatomic particle 19760
      composite particle 19760
        hadron 19760
          baryon 19760
            nucleon 19760
              atomic nucleus 19760
                atom 19760
                  main group element atom 19651
                    p-block element atom 19651
                      carbon group element atom 19570
                        carbon atom 19560
                          organic molecular entity 19560
                            organic group 18611
                              organic divalent group 18602
                                organodiyl group 18602
                                  carbonyl group 18519
                                    carbonyl compound 18519
                                      carboxylic acid 18195
                                        monocarboxylic acid 17594
                                          alpha,beta-unsaturated monocarboxylic acid 12210
                                            cinnamic acids 2417
                                              methoxycinnamic acid 19
                                                (2E)-3-(4-\{[1-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-(sulfooxy)propan-2-yl]oxy\}-3-methoxyphenyl)prop-2-enoic acid 0
                                                (2E)-3-(4-\{[3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-(sulfooxy)propan-2-yl]oxy\}-3-methoxyphenyl)prop-2-enoic acid 0
                                                (2E)-3-[4-(\{1,3-dihydroxy-1-[3-methoxy-4-(sulfooxy)phenyl]propan-2-yl\}oxy)-3-methoxyphenyl]prop-2-enoic acid 0
                                                3,4,5-trimethoxycinnamic acid 0
                                                3,4-dimethoxycinnamic acid + 0
                                                4-O-beta-D-glucosyl-trans-sinapic acid 0
                                                4-methoxycinnamic acid + 2
                                                5-hydroxyferulic acid + 0
                                                poacic acid 0
                                                sinapic acid + 18
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