ketamine - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	ketamine	go back to main search page
Accession:	CHEBI:6121	browse the term
Definition:	A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Synonyms:	related_synonym:	2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone; 2-(methylamino)-2-(2-chlorophenyl)cyclohexanone; 2-(o-chlorophenyl)-2-(methylamino)-cyclohexanone; Formula=C13H16ClNO; InChI=1S/C13H16ClNO/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14/h2-3,6-7,15H,4-5,8-9H2,1H3; InChIKey=YQEZLKZALYSWHR-UHFFFAOYSA-N; NMDA; SMILES=CNC1(CCCCC1=O)c1ccccc1Cl; dl-ketamine; ketamina; ketaminum; special K
	alt_id:	CHEBI:138833
	xref:	CAS:100477-72-3; CAS:6740-88-1; DrugBank:DB01221; Drug_Central:1523; HMDB:HMDB0015352; KEGG:C07525; KEGG:D08098
	xref_mesh:	MESH:D007649
	xref:	PMID:3783598; Patent:BE634208; Patent:US3254124; Reaxys:2216965; VSDB:2978; Wikipedia:Ketamine

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Genes (969)

ketamine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily A member 1

increases expression

Ketamine results in increased expression of ABCA1 mRNA

NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170

G

ATP binding cassette subfamily B member 1A

multiple interactions

ABCB1A protein affects the susceptibility to [Pentobarbital co-treated with Ketamine]

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily G member 1

increases expression

Ketamine results in increased expression of ABCG1 mRNA

NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948

G

abhydrolase domain containing 16A, phospholipase

increases expression

Ketamine results in increased expression of ABHD16A mRNA

NCBI chr20:3,719,089...3,733,952
Ensembl chr20:3,719,091...3,733,927

G

abhydrolase domain containing 5, lysophosphatidic acid acyltransferase

decreases expression

Ketamine results in decreased expression of ABHD5 mRNA

NCBI chr 8:122,000,241...122,026,447
Ensembl chr 8:122,000,389...122,026,447

G

acetyl-CoA acetyltransferase 2

decreases expression

Ketamine results in decreased expression of ACAT2 mRNA

NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821

G

acyl-CoA binding domain containing 3

decreases expression

Ketamine results in decreased expression of ACBD3 mRNA

NCBI chr13:92,455,813...92,484,556
Ensembl chr13:92,455,655...92,483,380

G

acyl-CoA binding domain containing 5

decreases expression

Ketamine results in decreased expression of ACBD5 mRNA

NCBI chr17:85,206,178...85,248,909
Ensembl chr17:85,206,303...85,248,215

G

angiotensin I converting enzyme

increases expression

Ketamine results in increased expression of ACE mRNA

NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131

G

acid phosphatase 6, lysophosphatidic

decreases expression

Ketamine results in decreased expression of ACP6 mRNA

NCBI chr 2:184,711,975...184,733,067
Ensembl chr 2:184,711,619...184,733,017

G

acrosin

increases expression

Ketamine results in increased expression of ACR mRNA

NCBI chr 7:120,636,581...120,644,474
Ensembl chr 7:120,638,321...120,644,474

G

acyl-CoA synthetase bubblegum family member 1

increases expression

Ketamine results in increased expression of ACSBG1 mRNA

NCBI chr 8:54,991,294...55,047,276
Ensembl chr 8:54,991,296...55,047,391

G

actin alpha 2, smooth muscle

multiple interactions
increases expression

2-(5-benzo(1,3)dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride inhibits the reaction [Ketamine results in increased expression of ACTA2 protein]
Ketamine results in increased expression of ACTA2 mRNA; Ketamine results in increased expression of ACTA2 protein

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

actin gamma 2, smooth muscle

decreases expression

Ketamine results in decreased expression of ACTG2 mRNA

NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465

G

activin A receptor type 1C

decreases expression

Ketamine results in decreased expression of ACVR1C mRNA

NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327

G

ADAM metallopeptidase domain 24

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of ADAM24 mRNA

NCBI chr16:51,578,278...51,584,265
Ensembl chr16:51,578,277...51,584,312

G

ArfGAP with dual PH domains 2

increases expression

Ketamine results in increased expression of ADAP2 mRNA

NCBI chr10:65,138,006...65,166,147
Ensembl chr10:65,138,020...65,165,604

G

aarF domain containing kinase 2

decreases expression

Ketamine results in decreased expression of ADCK2 mRNA

NCBI chr 4:68,348,853...68,362,725
Ensembl chr 4:68,348,864...68,374,608

G

adenylate cyclase 8

decreases expression

Ketamine results in decreased expression of ADCY8 mRNA

NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911

G

adenylate cyclase 9

increases expression

Ketamine results in increased expression of ADCY9 mRNA

NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066

G

adenylate cyclase activating polypeptide 1

decreases expression
multiple interactions

Ketamine results in decreased expression of ADCYAP1 mRNA
[ampullosporin co-treated with Ketamine] results in decreased expression of ADCYAP1 mRNA

PMID:16635253 PMID:20080153

NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773

G

adducin 2

decreases expression

Ketamine results in decreased expression of ADD2 mRNA

NCBI chr 4:118,444,594...118,538,505
Ensembl chr 4:118,497,416...118,538,505

G

adhesion G protein-coupled receptor B2

increases expression

Ketamine results in increased expression of ADGRB2 mRNA

NCBI chr 5:142,299,190...142,362,540
Ensembl chr 5:142,331,329...142,362,540

G

alpha-fetoprotein

increases expression

Ketamine results in increased expression of AFP mRNA

NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480

G

angiotensinogen

decreases expression
increases expression
multiple interactions

Ketamine results in decreased expression of AGT protein
Ketamine results in increased expression of AGT mRNA
[ampullosporin co-treated with Ketamine] results in increased expression of AGT mRNA

PMID:6349867 PMID:16635253 PMID:20080153

NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977

G

angiotensin II receptor-associated protein

increases expression

Ketamine results in increased expression of AGTRAP mRNA

NCBI chr 5:158,507,427...158,519,036
Ensembl chr 5:158,508,749...158,519,036

G

aryl hydrocarbon receptor

decreases expression

Ketamine results in decreased expression of AHR mRNA

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

allograft inflammatory factor 1

decreases expression
multiple interactions

Ketamine results in decreased expression of AIF1 mRNA
Cannabidiol inhibits the reaction [Ketamine results in decreased expression of AIF1 mRNA]
Ketamine results in decreased expression of AIF1 protein

PMID:31823199 PMID:36172893

NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668

G

A-kinase anchoring protein 9

decreases expression

Ketamine results in decreased expression of AKAP9 mRNA

NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606

G

5'-aminolevulinate synthase 1

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of ALAS1 mRNA

NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917

G

albumin

increases expression

Ketamine results in increased expression of ALB mRNA

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

aldehyde dehydrogenase 18 family, member A1

decreases expression

Ketamine results in decreased expression of ALDH18A1 mRNA

NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890

G

aldolase, fructose-bisphosphate C

increases expression

Ketamine results in increased expression of ALDOC mRNA

NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066

G

ALMS1, centrosome and basal body associated protein

decreases expression

Ketamine results in decreased expression of ALMS1 mRNA

NCBI chr 4:118,125,581...118,226,005
Ensembl chr 4:118,125,607...118,226,005

G

alkaline phosphatase, biomineralization associated

multiple interactions

[ampullosporin co-treated with Ketamine] results in decreased expression of ALPL mRNA

NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446

G

anti-Mullerian hormone receptor type 2

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of AMHR2 mRNA

NCBI chr 7:133,579,152...133,588,874
Ensembl chr 7:133,579,393...133,588,258

G

adhesion molecule with Ig like domain 2

decreases expression

Ketamine results in decreased expression of AMIGO2 mRNA

NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695

G

anaphase promoting complex subunit 1

increases expression

Ketamine results in increased expression of ANAPC1 mRNA

NCBI chr 3:115,850,117...115,930,259
Ensembl chr 3:115,850,185...115,930,273

G

angiopoietin-like 4

increases expression

Ketamine results in increased expression of ANGPTL4 mRNA

NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519

G

ankyrin repeat domain 42

decreases expression

Ketamine results in decreased expression of ANKRD42 mRNA

NCBI chr 1:146,648,080...146,691,086
Ensembl chr 1:146,648,080...146,691,108

G

annexin A11

increases expression

Ketamine results in increased expression of ANXA11 mRNA

NCBI chr16:1,412,373...1,457,814
Ensembl chr16:1,410,756...1,457,797

G

annexin A3

decreases expression

Ketamine results in decreased expression of ANXA3 mRNA

NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617

G

annexin A4

increases expression

Ketamine results in increased expression of ANXA4 mRNA

NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161

G

annexin A5

decreases expression
multiple interactions

Ketamine results in decreased expression of ANXA5 mRNA
[ampullosporin co-treated with Ketamine] results in decreased expression of ANXA5 mRNA

PMID:16635253 PMID:20080153

NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369

G

adaptor related protein complex 2 subunit mu 1

multiple interactions

Ketamine inhibits the reaction [NTRK2 protein binds to AP2M1 protein]

NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140

G

adaptor related protein complex 3 subunit mu 1

decreases expression

Ketamine results in decreased expression of AP3M1 mRNA

NCBI chr15:3,246,616...3,264,846
Ensembl chr15:3,246,926...3,264,844

G

adaptor related protein complex 5 subunit mu 1

decreases expression

Ketamine results in decreased expression of AP5M1 mRNA

NCBI chr15:22,355,478...22,385,222
Ensembl chr15:22,355,500...22,377,750

G

apurinic/apyrimidinic endodeoxyribonuclease 2

decreases expression

Ketamine results in decreased expression of APEX2 mRNA

NCBI chr X:19,425,684...19,508,459
Ensembl chr X:19,487,419...19,508,439

G

aprataxin and PNKP like factor

decreases expression

Ketamine results in decreased expression of APLF mRNA

NCBI chr 4:120,070,471...120,122,656
Ensembl chr 4:120,070,471...120,122,633

G

adipocyte plasma membrane associated protein

increases expression

Ketamine results in increased expression of APMAP mRNA

NCBI chr 3:139,409,021...139,437,296
Ensembl chr 3:139,409,022...139,437,341

G

apolipoprotein E

decreases response to substance
increases expression

APOE results in decreased susceptibility to Ketamine
Ketamine results in increased expression of APOE mRNA

PMID:9778666 PMID:20080153

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

G

amyloid beta precursor protein

increases expression
multiple interactions

Ketamine results in increased expression of APP mRNA
[Ketamine results in increased cleavage of APP protein] which results in increased abundance of amyloid beta-protein (1-40); [Ketamine results in increased cleavage of APP protein] which results in increased abundance of amyloid beta-protein (1-42); Ketamine results in decreased expression of and results in increased cleavage of APP protein; Monensin inhibits the reaction [[Ketamine results in increased cleavage of APP protein] which results in increased abundance of amyloid beta-protein (1-40)]; Monensin inhibits the reaction [[Ketamine results in increased cleavage of APP protein] which results in increased abundance of amyloid beta-protein (1-42)]
Ketamine results in decreased expression of and results in increased cleavage of APP protein; Monensin inhibits the reaction [Ketamine results in decreased expression of and results in increased cleavage of APP protein]

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

amyloid beta precursor protein binding protein 2

decreases expression

Ketamine results in decreased expression of APPBP2 mRNA

NCBI chr10:70,057,774...70,099,877
Ensembl chr10:70,057,774...70,099,835

G

ARF GTPase 3

multiple interactions

[ampullosporin co-treated with Ketamine] results in decreased expression of ARF3 mRNA

NCBI chr 7:129,886,082...129,912,022
Ensembl chr 7:129,886,082...129,912,002

G

ARF guanine nucleotide exchange factor 1

decreases expression

Ketamine results in decreased expression of ARFGEF1 mRNA

NCBI chr 5:8,982,061...9,076,326
Ensembl chr 5:8,981,540...9,076,326

G

Rho GTPase activating protein 5

decreases expression

Ketamine results in decreased expression of ARHGAP5 mRNA

NCBI chr 6:69,975,904...70,039,299
Ensembl chr 6:69,976,214...70,037,660

G

ariadne RBR E3 ubiquitin protein ligase 1

decreases expression

Ketamine results in decreased expression of ARIH1 mRNA

NCBI chr 8:59,777,378...59,879,762
Ensembl chr 8:59,777,379...59,880,245

G

ARF like GTPase 6

decreases expression

Ketamine results in decreased expression of ARL6 mRNA

NCBI chr11:40,711,878...40,738,254
Ensembl chr11:40,712,022...40,737,937

G

ARF like GTPase 6 interacting protein 6

decreases expression

Ketamine results in decreased expression of ARL6IP6 mRNA

NCBI chr 3:37,689,994...37,720,358
Ensembl chr 3:37,690,382...37,718,018

G

armadillo repeat containing 10

decreases expression

Ketamine results in decreased expression of ARMC10 mRNA

NCBI chr 4:13,399,004...13,414,594
Ensembl chr 4:13,395,207...13,414,548

G

ADP-ribosyltransferase 3

increases expression

Ketamine results in increased expression of ART3 mRNA

NCBI chr14:15,637,230...15,719,442
Ensembl chr14:15,637,237...15,665,407

G

achaete-scute family bHLH transcription factor 1

decreases expression

Ketamine results in decreased expression of ASCL1 mRNA

NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993

G

acid sensing ion channel subunit family member 4

increases expression

Ketamine results in increased expression of ASIC4 mRNA

NCBI chr 9:76,941,532...76,962,900
Ensembl chr 9:76,941,532...76,962,900

G

aspartate dehydrogenase domain containing

increases expression

Ketamine results in increased expression of ASPDH mRNA

NCBI chr 1:94,956,327...94,960,722
Ensembl chr 1:94,958,316...94,960,722

G

activating transcription factor 4

increases expression

Ketamine results in increased expression of ATF4 mRNA

NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446

G

activating transcription factor 6

increases expression

Ketamine results in increased expression of ATF6 mRNA

NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177

G

autophagy related 12

increases expression

Ketamine results in increased expression of ATG12 mRNA

NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418

G

ATPase 13A4

increases expression

Ketamine results in increased expression of ATP13A4 mRNA

NCBI chr11:71,222,196...71,359,933
Ensembl chr11:71,226,161...71,359,933

G

ATPase Na+/K+ transporting subunit alpha 1

increases expression

Ketamine results in increased expression of ATP1A1 mRNA

NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837

G

ATPase Na+/K+ transporting subunit alpha 2

increases expression

Ketamine results in increased expression of ATP1A2 mRNA

NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544

G

ATPase Na+/K+ transporting subunit alpha 3

increases expression

Ketamine results in increased expression of ATP1A3 mRNA

NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918

G

ATPase H+ transporting V0 subunit a1

increases expression

Ketamine results in increased expression of ATP6V0A1 mRNA

NCBI chr10:85,935,802...85,989,901
Ensembl chr10:85,935,854...85,989,895

G

ATPase H+ transporting V1 subunit C2

increases expression

Ketamine results in increased expression of ATP6V1C2 mRNA

NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028

G

ATPase copper transporting alpha

decreases expression

Ketamine results in decreased expression of ATP7A mRNA

NCBI chr X:71,094,144...71,201,550
Ensembl chr X:71,094,202...71,198,354

G

beta-1,4-glucuronyltransferase 1

increases expression

Ketamine results in increased expression of B4GAT1 mRNA

NCBI chr 1:202,343,268...202,345,490
Ensembl chr 1:202,343,240...202,346,065

G

beta-secretase 1

increases expression
multiple interactions

Ketamine results in increased expression of BACE1 protein
Ketamine results in increased expression of and affects the localization of BACE1 protein; Monensin inhibits the reaction [Ketamine results in increased expression of and affects the localization of BACE1 protein]

NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876

G

BAG cochaperone 3

increases expression

Ketamine results in increased expression of BAG3 mRNA

NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858

G

BAG cochaperone 5

multiple interactions
increases expression

BAG5 protein inhibits the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of CASP3 mRNA]]; lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of BAG5 mRNA]; lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of BAG5 protein]; MIR22 affects the reaction [Ketamine results in increased expression of BAG5 mRNA]; MIR22 affects the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of BAG5 protein]]; MIR22 inhibits the reaction [Ketamine results in increased expression of BAG5 protein]
Ketamine results in increased expression of BAG5 mRNA; Ketamine results in increased expression of BAG5 protein

NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970

G

BAR/IMD domain containing adaptor protein 2

increases expression

Ketamine results in increased expression of BAIAP2 mRNA

NCBI chr10:105,223,065...105,290,130
Ensembl chr10:105,223,090...105,290,134

G

Btg3 associated nuclear protein

decreases expression

Ketamine results in decreased expression of BANP mRNA

NCBI chr19:50,007,710...50,082,742
Ensembl chr19:50,007,881...50,082,738

G

BCL2 associated X, apoptosis regulator

affects localization
increases expression
multiple interactions

Ketamine affects the localization of BAX protein
Ketamine results in increased expression of BAX mRNA; Ketamine results in increased expression of BAX protein
Curcumin inhibits the reaction [Ketamine results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [Ketamine results in increased expression of BAX protein]; TRPV4 protein affects the reaction [Ketamine results in increased expression of BAX mRNA]; TRPV4 protein affects the reaction [Ketamine results in increased expression of BAX protein]

PMID:18456338 PMID:19001360 PMID:25937004 PMID:33536391 PMID:36305173

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

branched chain keto acid dehydrogenase E1 subunit alpha

increases expression

Ketamine results in increased expression of BCKDHA mRNA

NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862

G

BCL2, apoptosis regulator

multiple interactions
decreases expression

Curcumin affects the reaction [Ketamine results in decreased expression of BCL2 protein]; Curcumin inhibits the reaction [Ketamine results in decreased expression of BCL2 mRNA]; TRPV4 protein affects the reaction [Ketamine results in decreased expression of BCL2 mRNA]; TRPV4 protein affects the reaction [Ketamine results in decreased expression of BCL2 protein]
Ketamine results in decreased expression of BCL2 mRNA; Ketamine results in decreased expression of BCL2 protein
LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in decreased expression of BCL2 protein]]; lipoxin A4 methyl ester inhibits the reaction [Ketamine results in decreased expression of BCL2 protein]

PMID:33536391 PMID:36305173 PMID:36907275

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

BCLAF1 and THRAP3 family member 3

decreases expression

Ketamine results in decreased expression of BCLAF3 mRNA

NCBI chr X:35,257,228...35,328,883
Ensembl chr X:35,263,576...35,328,816

G

BCL6 co-repressor-like 1

decreases expression

Ketamine results in decreased expression of BCORL1 mRNA

NCBI chr X:127,516,504...127,584,529
Ensembl chr X:127,537,538...127,584,087

G

BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone

decreases expression

Ketamine results in decreased expression of BCS1L mRNA

NCBI chr 9:76,164,925...76,168,940
Ensembl chr 9:76,164,932...76,168,938

G

bradykinin receptor B1

increases expression

Ketamine results in increased expression of BDKRB1 mRNA; Ketamine results in increased expression of BDKRB1 protein

NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747

G

brain-derived neurotrophic factor

multiple interactions
increases expression
decreases expression

Ketamine inhibits the reaction [Isoflurophate results in decreased expression of BDNF protein]; Ketamine inhibits the reaction [Pilocarpine results in increased expression of BDNF mRNA]
Sirolimus inhibits the reaction [Ketamine results in increased expression of BDNF protein]
Ketamine results in decreased expression of BDNF mRNA; Ketamine results in decreased expression of BDNF protein

PMID:8635431 PMID:32592718 PMID:33022268 PMID:36172893

NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615

G

beclin 1

increases expression

Ketamine results in increased expression of BECN1 protein

NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742

G

basic helix-loop-helix family, member e22

decreases expression

Ketamine results in decreased expression of BHLHE22 mRNA

NCBI chr 2:100,486,400...100,489,510
Ensembl chr 2:100,486,400...100,489,510

G

basic helix-loop-helix family, member e40

increases expression

Ketamine results in increased expression of BHLHE40 mRNA

NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774

G

basic helix-loop-helix family, member e41

increases expression

Ketamine results in increased expression of BHLHE41 mRNA

NCBI chr 4:178,834,264...178,838,618
Ensembl chr 4:178,834,271...178,838,468

G

BMI1 proto-oncogene, polycomb ring finger

decreases expression

Ketamine results in decreased expression of BMI1 mRNA

NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690

G

BCL2 interacting protein 3

decreases expression

Ketamine results in decreased expression of BNIP3 mRNA

NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359

G

B-Raf proto-oncogene, serine/threonine kinase

multiple interactions

Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of BRAF protein]

NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463

G

BMP/retinoic acid inducible neural specific 2

increases expression

Ketamine results in increased expression of BRINP2 mRNA

NCBI chr13:70,431,006...70,532,766
Ensembl chr13:70,431,010...70,531,810

G

BTG anti-proliferation factor 1

decreases expression
multiple interactions

Ketamine results in decreased expression of BTG1 mRNA
[ampullosporin co-treated with Ketamine] results in increased expression of BTG1 mRNA

PMID:16635253 PMID:20080153

NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649

G

BUB1 mitotic checkpoint serine/threonine kinase B

decreases expression

Ketamine results in decreased expression of BUB1B mRNA

NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547

G

similar to human chromosome 5 open reading frame 24

decreases expression

Ketamine results in decreased expression of C17H5ORF24 mRNA

NCBI chr17:8,923,041...8,932,958
Ensembl chr17:8,922,675...8,933,356

G

complement C1q A chain

increases expression

Ketamine results in increased expression of C1QA mRNA

NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534

G

complement C1q B chain

increases expression

Ketamine results in increased expression of C1QB mRNA

NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407

G

complement C1q C chain

increases expression
decreases expression
multiple interactions

Ketamine results in increased expression of C1QC mRNA
Ketamine results in decreased expression of C1QC mRNA
Cannabidiol inhibits the reaction [Ketamine results in decreased expression of C1QC mRNA]

PMID:20080153 PMID:31823199

NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017

G

complement C2

increases expression

Ketamine results in increased expression of C2 mRNA

NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505

G

C2CD2-like

increases expression

Ketamine results in increased expression of C2CD2L mRNA

NCBI chr 8:44,648,074...44,658,856
Ensembl chr 8:44,648,079...44,658,340

G

C2 calcium-dependent domain containing 4B

increases expression

Ketamine results in increased expression of C2CD4B mRNA

NCBI chr 8:68,372,793...68,396,477
Ensembl chr 8:68,384,847...68,396,328

G

complement component 4 binding protein, beta

increases expression

Ketamine results in increased expression of C4BPB mRNA

NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817

G

caspase activity and apoptosis inhibitor 1

decreases expression

Ketamine results in decreased expression of CAAP1 mRNA

NCBI chr 5:109,313,253...109,414,323
Ensembl chr 5:109,361,912...109,414,314

G

ciliary associated calcium binding coiled-coil 1

increases expression

Ketamine results in increased expression of CABCOCO1 mRNA

NCBI chr20:20,058,492...20,167,973
Ensembl chr20:20,058,454...20,167,725

G

calcium binding protein 7

increases expression

Ketamine results in increased expression of CABP7 mRNA

NCBI chr14:79,598,822...79,609,172
Ensembl chr14:79,598,827...79,609,240

G

calcium voltage-gated channel auxiliary subunit gamma 2

increases expression

Ketamine results in increased expression of CACNG2 mRNA

NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227

G

calbindin 2

increases expression
multiple interactions

Ketamine results in increased expression of CALB2 mRNA
[ampullosporin co-treated with Ketamine] results in increased expression of CALB2 mRNA

PMID:16635253 PMID:20080153

NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438

G

calcium/calmodulin-dependent protein kinase kinase 1

increases expression

Ketamine results in increased expression of CAMKK1 mRNA

NCBI chr10:57,637,335...57,660,498
Ensembl chr10:57,637,391...57,660,498

G

calcium/calmodulin-dependent protein kinase kinase 2

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of CAMKK2 mRNA

NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279

G

cullin-associated and neddylation-dissociated 2 (putative)

decreases expression

Ketamine results in decreased expression of CAND2 mRNA

NCBI chr 4:148,835,050...148,864,039
Ensembl chr 4:148,835,053...148,863,153

G

calcium activated nucleotidase 1

increases expression

Ketamine results in increased expression of CANT1 mRNA

NCBI chr10:103,637,079...103,650,240
Ensembl chr10:103,531,504...103,650,109

G

carbonic anhydrase 4

increases expression

Ketamine results in increased expression of CAR4 mRNA

NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501

G

carbonic anhydrase 7

increases expression

Ketamine results in increased expression of CAR7 mRNA

NCBI chr19:429,063...438,478
Ensembl chr19:429,075...438,467

G

carbonic anhydrase 8

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of CAR8 mRNA

NCBI chr 5:21,302,940...21,402,395
Ensembl chr 5:21,305,383...21,402,374

G

caspase 3

increases activity
increases expression
multiple interactions
increases cleavage

Ketamine results in increased activity of CASP3 protein
Ketamine results in increased expression of CASP3 mRNA; Ketamine results in increased expression of CASP3 protein; Ketamine results in increased expression of CASP3 protein modified form
BAG5 protein inhibits the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of CASP3 mRNA]]; Curcumin inhibits the reaction [Ketamine results in increased expression of CASP3 mRNA]; Curcumin inhibits the reaction [Ketamine results in increased expression of CASP3 protein modified form]; Curcumin inhibits the reaction [Ketamine results in increased expression of CASP3 protein]; lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased activity of CASP3 protein]; lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of CASP3 mRNA]; MIR22 affects the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of CASP3 mRNA]]; MIR22 inhibits the reaction [Ketamine results in increased activity of CASP3 protein]; TRPV4 protein affects the reaction [Ketamine results in increased cleavage of CASP3 protein]; TRPV4 protein affects the reaction [Ketamine results in increased expression of CASP3 mRNA]
LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased cleavage of CASP3 protein]]; lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased cleavage of CASP3 protein]

PMID:17920787 PMID:19001360 PMID:25937004 PMID:32153215 PMID:33536391 More...

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 6

increases activity

Ketamine results in increased activity of CASP6 protein

NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502

G

caspase 9

increases activity
increases expression
multiple interactions

Ketamine results in increased activity of CASP9 protein
Ketamine results in increased expression of CASP9 mRNA
lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased activity of CASP9 protein]; lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of CASP9 mRNA]; MIR22 inhibits the reaction [Ketamine results in increased activity of CASP9 protein]

PMID:19001360 PMID:20080153 PMID:34670429

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

catalase

decreases activity
multiple interactions

Ketamine results in decreased activity of CAT protein
TRPV4 protein affects the reaction [Ketamine results in decreased activity of CAT protein]

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

carbonyl reductase 3

decreases expression

Ketamine results in decreased expression of CBR3 mRNA

NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875

G

chromobox 1

decreases expression

Ketamine results in decreased expression of CBX1 mRNA

NCBI chr10:81,770,307...81,789,981
Ensembl chr10:81,770,342...81,791,096

G

chromobox 7

increases expression

Ketamine results in increased expression of CBX7 mRNA

NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973

G

coiled-coil domain containing 115

increases expression

Ketamine results in increased expression of CCDC115 mRNA

NCBI chr 9:36,650,384...36,654,348
Ensembl chr 9:36,649,271...36,653,946

G

coiled-coil domain containing 50

decreases expression

Ketamine results in decreased expression of CCDC50 mRNA

NCBI chr11:73,332,798...73,395,333
Ensembl chr11:73,334,248...73,395,150

G

coiled-coil domain containing 85A

decreases expression

Ketamine results in decreased expression of CCDC85A mRNA

NCBI chr14:102,126,574...102,359,207
Ensembl chr14:102,129,029...102,359,058

G

coiled-coil domain containing 90B

decreases expression

Ketamine results in decreased expression of CCDC90B mRNA

NCBI chr 1:146,632,756...146,646,314
Ensembl chr 1:146,633,036...146,647,338

G

cholecystokinin

multiple interactions

[ampullosporin co-treated with Ketamine] results in decreased expression of CCK mRNA

NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084

G

C-C motif chemokine ligand 5

multiple interactions

[Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 protein]

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

cyclin A2

decreases expression

Ketamine results in decreased expression of CCNA2 mRNA

NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577

G

cyclin D1

decreases expression

Ketamine results in decreased expression of CCND1 mRNA

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin D1 binding protein 1

decreases expression

Ketamine results in decreased expression of CCNDBP1 mRNA

NCBI chr 3:107,962,402...107,974,234
Ensembl chr 3:107,962,261...107,974,233

G

cell cycle progression 1

increases expression

Ketamine results in increased expression of CCPG1 mRNA

NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430

G

C-C motif chemokine receptor 5

increases expression

Ketamine results in increased expression of CCR5 mRNA

NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260

G

centriole, cilia and spindle-associated protein

increases expression

Ketamine results in increased expression of CCSAP mRNA

NCBI chr19:51,824,954...51,843,469
Ensembl chr19:51,826,994...51,842,753

G

CD24 molecule

decreases expression

Ketamine results in decreased expression of CD24 mRNA

NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662

G

CD38 molecule

increases expression

Ketamine results in increased expression of CD38 mRNA

NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986

G

Cd63 molecule

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of CD63 mRNA

NCBI chr 7:1,325,108...1,340,447
Ensembl chr 7:1,325,103...1,399,178

G

CD83 molecule

increases expression

Ketamine results in increased expression of CD83 mRNA

NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083

G

CDC42 effector protein 3

decreases expression

Ketamine results in decreased expression of CDC42EP3 mRNA

NCBI chr 6:15,710,894...15,731,366
Ensembl chr 6:15,708,730...15,732,721

G

cell division cycle 6

decreases expression

Ketamine results in decreased expression of CDC6 mRNA

NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011

G

cell division cycle associated 7

decreases expression

Ketamine results in decreased expression of CDCA7 mRNA

NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353

G

cadherin 1

decreases expression
multiple interactions

Ketamine results in decreased expression of CDH1 protein
2-(5-benzo(1,3)dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride inhibits the reaction [Ketamine results in decreased expression of CDH1 protein]
Ketamine results in decreased expression of CDH1 mRNA; Ketamine results in decreased expression of CDH1 protein

NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775

G

cadherin 11

decreases expression

Ketamine results in decreased expression of CDH11 mRNA

NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272

G

cadherin 15

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of CDH15 mRNA

NCBI chr19:50,903,757...50,927,151
Ensembl chr19:50,903,638...50,927,105

G

cadherin 7

decreases expression

Ketamine results in decreased expression of CDH7 mRNA

NCBI chr13:26,672,058...26,821,571
Ensembl chr13:26,672,484...26,819,846

G

cyclin-dependent kinase 1

decreases expression

Ketamine results in decreased expression of CDK1 mRNA

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cyclin-dependent kinase 14

decreases expression

Ketamine results in decreased expression of CDK14 mRNA

NCBI chr 4:28,666,416...29,258,865
Ensembl chr 4:28,666,843...29,258,861

G

cerebral dopamine neurotrophic factor

affects expression

Ketamine affects the expression of CDNF mRNA

NCBI chr17:74,714,564...74,728,639
Ensembl chr17:74,713,564...74,728,639

G

CCAAT/enhancer binding protein beta

increases expression

Ketamine results in increased expression of CEBPB mRNA

NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473

G

centromere protein C

decreases expression

Ketamine results in decreased expression of CENPC1 mRNA

NCBI chr14:21,988,067...22,046,732
Ensembl chr14:21,988,144...22,055,476

G

centrosomal protein 70

decreases expression

Ketamine results in decreased expression of CEP70 mRNA

NCBI chr 8:99,810,270...99,863,279
Ensembl chr 8:99,810,367...99,862,855

G

cilia and flagella associated protein 126

increases expression

Ketamine results in increased expression of CFAP126 mRNA

NCBI chr13:83,526,657...83,542,552
Ensembl chr13:83,526,657...83,542,552

G

cilia and flagella associated protein 410

increases expression

Ketamine results in increased expression of CFAP410 mRNA

NCBI chr20:10,687,863...10,694,736
Ensembl chr20:10,687,863...10,694,737

G

chromodomain helicase DNA binding protein 7

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of CHD7 mRNA

NCBI chr 5:21,812,007...21,995,358
Ensembl chr 5:21,812,070...21,995,358

G

chitinase 3 like 1

increases expression

Ketamine results in increased expression of CHI3L1 mRNA

NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787

G

cysteine and histidine rich domain containing 1

decreases expression

Ketamine results in decreased expression of CHORDC1 mRNA

NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162

G

chondroitin polymerizing factor 2

increases expression

Ketamine results in increased expression of CHPF2 mRNA

NCBI chr 4:10,578,470...10,585,940
Ensembl chr 4:10,580,462...10,585,916

G

cholinergic receptor, muscarinic 1

multiple interactions

Ketamine inhibits the reaction [Scopolamine Derivatives binds to CHRM1 protein]

NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356

G

cholinergic receptor, muscarinic 2

multiple interactions

Ketamine inhibits the reaction [Scopolamine Derivatives binds to CHRM2 protein]

NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103

G

cholinergic receptor, muscarinic 3

multiple interactions

Ketamine inhibits the reaction [Scopolamine Derivatives binds to CHRM3 protein]

NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278

G

cytosolic iron-sulfur assembly component 3

increases expression

Ketamine results in increased expression of CIAO3 mRNA

NCBI chr10:14,795,888...14,804,953
Ensembl chr10:14,795,961...14,804,950

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of CITED2 mRNA

NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897

G

claudin 11

increases expression

Ketamine results in increased expression of CLDN11 mRNA

NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050

G

C-type lectin domain family 2, member L

increases expression

Ketamine results in increased expression of CLEC2L mRNA

NCBI chr 4:67,392,118...67,414,539
Ensembl chr 4:67,397,873...67,414,537

G

C-type lectin domain family 4, member A3

increases expression

Ketamine results in increased expression of CLEC4A3 mRNA

NCBI chr 4:156,214,030...156,224,818
Ensembl chr 4:156,214,718...156,224,817

G

CDC-like kinase 1

decreases expression

Ketamine results in decreased expression of CLK1 mRNA

NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000

G

CXADR-like membrane protein

decreases expression

Ketamine results in decreased expression of CLMP mRNA

NCBI chr 8:41,060,527...41,168,841
Ensembl chr 8:41,060,799...41,168,838

G

clusterin

increases expression

Ketamine results in increased expression of CLU mRNA

NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315

G

CKLF-like MARVEL transmembrane domain containing 5

increases expression

Ketamine results in increased expression of CMTM5 mRNA

NCBI chr15:28,412,624...28,415,304
Ensembl chr15:28,412,624...28,415,287

G

CKLF-like MARVEL transmembrane domain containing 8

increases expression

Ketamine results in increased expression of CMTM8 mRNA

NCBI chr 8:114,481,730...114,547,107
Ensembl chr 8:114,481,982...114,547,083

G

Cnksr family member 3

increases expression

Ketamine results in increased expression of CNKSR3 mRNA

NCBI chr 1:43,499,273...43,591,630
Ensembl chr 1:43,499,487...43,591,635

G

cannabinoid receptor 1

decreases expression

Ketamine results in decreased expression of CNR1 mRNA

NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099

G

cytochrome c oxidase assembly factor 4 homolog

decreases expression

Ketamine results in decreased expression of COA4 mRNA

NCBI chr 1:154,882,199...154,885,445
Ensembl chr 1:154,882,155...154,888,174

G

cytochrome c oxidase assembly factor 7

increases expression

Ketamine results in increased expression of COA7 mRNA

NCBI chr 5:123,069,356...123,080,942
Ensembl chr 5:123,069,371...123,080,199

G

component of oligomeric golgi complex 6

decreases expression

Ketamine results in decreased expression of COG6 mRNA

NCBI chr 2:137,062,127...137,099,176
Ensembl chr 2:137,061,346...137,099,190

G

collagen type XI alpha 1 chain

decreases expression

Ketamine results in decreased expression of COL11A1 mRNA

NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853

G

collagen type XVIII alpha 1 chain

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of COL18A1 mRNA

NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593

G

COMM domain containing 5

increases expression

Ketamine results in increased expression of COMMD5 mRNA

NCBI chr 7:108,621,766...108,623,616
Ensembl chr 7:108,598,673...108,624,764

G

catechol-O-methyltransferase

increases expression

Ketamine results in increased expression of COMT mRNA

NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642

G

coenzyme Q8A

increases expression

Ketamine results in increased expression of COQ8A mRNA

NCBI chr13:91,904,731...91,933,588
Ensembl chr13:91,904,739...91,931,431

G

cortistatin

increases expression

Ketamine results in increased expression of CORT mRNA

NCBI chr 5:159,560,591...159,562,032

G

cytochrome c oxidase subunit 6A2

increases expression

Ketamine results in increased expression of COX6A2 mRNA

NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274

G

CRACD like

increases expression

Ketamine results in increased expression of CRACDL mRNA

NCBI chr 9:39,834,321...39,950,763
Ensembl chr 9:39,834,833...39,951,086

G

CGRP receptor component

increases expression

Ketamine results in increased expression of CRCP mRNA

NCBI chr12:26,623,968...26,659,756
Ensembl chr12:26,623,976...26,768,225

G

cellular repressor of E1A-stimulated genes 1

increases expression

Ketamine results in increased expression of CREG1 mRNA

NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308

G

cysteine-rich with EGF-like domains 2

decreases expression

Ketamine results in decreased expression of CRELD2 mRNA

NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:119,909,633...119,916,543

G

corticotropin releasing hormone

decreases expression

Ketamine results in decreased expression of CRH mRNA

NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919

G

cardiolipin synthase 1

decreases expression

Ketamine results in decreased expression of CRLS1 mRNA

NCBI chr 3:120,119,822...120,138,674
Ensembl chr 3:120,119,852...120,138,655

G

cartilage acidic protein 1

increases expression

Ketamine results in increased expression of CRTAC1 mRNA

NCBI chr 1:241,091,679...241,233,677
Ensembl chr 1:241,078,864...241,233,421

G

crystallin, alpha B

increases expression

Ketamine results in increased expression of CRYAB mRNA

NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157

G

colony stimulating factor 1 receptor

decreases expression

Ketamine results in decreased expression of CSF1R mRNA

NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415

G

cysteine and glycine-rich protein 2

multiple interactions

[ampullosporin co-treated with Ketamine] results in decreased expression of CSRP2 mRNA

NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745

G

catenin beta 1

increases expression
multiple interactions

Ketamine results in increased expression of CTNNB1 protein
Chir 99021 promotes the reaction [Ketamine results in increased expression of CTNNB1 protein]

NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111

G

cathepsin E

increases expression

Ketamine results in increased expression of CTSE mRNA

NCBI chr13:43,091,954...43,114,509
Ensembl chr13:43,092,128...43,114,502

G

cathepsin K

increases expression

Ketamine results in increased expression of CTSK mRNA

NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550

G

cathepsin S

increases expression

Ketamine results in increased expression of CTSS mRNA

NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483

G

CTTNBP2 N-terminal like

decreases expression

Ketamine results in decreased expression of CTTNBP2NL mRNA

NCBI chr 2:192,507,963...192,554,548
Ensembl chr 2:192,507,963...192,541,101

G

C-X3-C motif chemokine ligand 1

increases expression

Ketamine results in increased expression of CX3CL1 mRNA

NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833

G

C-X3-C motif chemokine receptor 1

decreases expression

Ketamine results in decreased expression of CX3CR1 mRNA; Ketamine results in decreased expression of CX3CR1 protein

NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014

G

C-X-C motif chemokine ligand 3

multiple interactions

[Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 protein]

NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511

G

CXXC finger protein 4

decreases expression

Ketamine results in decreased expression of CXXC4 mRNA

NCBI chr 2:222,664,148...222,689,365
Ensembl chr 2:222,664,771...222,689,365

G

cytochrome b5 reductase 3

increases expression

Ketamine results in increased expression of CYB5R3 mRNA

NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298

G

cytochrome b-245 alpha chain

increases expression

Ketamine results in increased expression of CYBA

NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721

G

cytochrome b-245 beta chain

increases expression

Ketamine results in increased expression of CYBB

NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586

G

cytoplasmic FMR1 interacting protein 2

multiple interactions

[ampullosporin co-treated with Ketamine] results in decreased expression of CYFIP2 mRNA

NCBI chr10:30,621,318...30,741,113
Ensembl chr10:30,621,318...30,741,113

G

cytochrome P450, family 11, subfamily a, polypeptide 1

increases expression

Ketamine results in increased expression of CYP11A1 mRNA

NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression

Ketamine results in increased expression of CYP1A1 protein

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 2, subfamily b, polypeptide 1

increases expression

Ketamine results in increased expression of CYP2B1 protein

NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052

G

cytochrome P450, family 2, subfamily e, polypeptide 1

increases expression

Ketamine results in increased expression of CYP2E1 protein

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 3, subfamily a, polypeptide 2

increases expression
multiple interactions
decreases expression

Ketamine results in increased expression of CYP3A2 protein
Ketamine results in decreased expression of and results in decreased activity of CYP3A4 protein
Ketamine results in decreased expression of CYP3A4 mRNA

PMID:16076768 PMID:18845661

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1

increases expression

Ketamine results in increased expression of CYP3A23-3A1 protein

NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030

G

cytochrome P450, family 46, subfamily a, polypeptide 1

increases expression

Ketamine results in increased expression of CYP46A1 mRNA

NCBI chr 6:127,247,543...127,274,765
Ensembl chr 6:127,243,315...127,274,760

G

cytohesin 4

decreases expression
multiple interactions

Ketamine results in decreased expression of CYTH4 mRNA
Cannabidiol inhibits the reaction [Ketamine results in decreased expression of CYTH4 mRNA]

NCBI chr 7:110,152,232...110,176,726
Ensembl chr 7:110,152,272...110,176,741

G

diacylglycerol lipase, beta

decreases expression

Ketamine results in decreased expression of DAGLB mRNA

NCBI chr12:11,059,732...11,102,170
Ensembl chr12:11,059,732...11,102,154

G

D-amino-acid oxidase

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of DAO mRNA

NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741

G

dysbindin domain containing 1

decreases expression

Ketamine results in decreased expression of DBNDD1 mRNA

NCBI chr19:51,539,154...51,548,441
Ensembl chr19:51,539,148...51,548,444

G

DDB1 and CUL4 associated factor 13

decreases expression

Ketamine results in decreased expression of DCAF13 mRNA

NCBI chr 7:70,160,983...70,196,142
Ensembl chr 7:70,160,941...70,196,142

G

dCMP deaminase

decreases expression

Ketamine results in decreased expression of DCTD mRNA

NCBI chr16:44,066,952...44,098,654
Ensembl chr16:44,055,128...44,098,446

G

doublecortin

decreases expression

Ketamine results in decreased expression of DCX protein

NCBI chr X:107,430,767...107,573,612
Ensembl chr X:107,430,767...107,507,476

G

DNA-damage inducible transcript 3

increases expression
multiple interactions

Ketamine results in increased expression of DDIT3 mRNA
LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of DDIT3 protein]]; lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of DDIT3 protein]

PMID:35728656 PMID:36907275

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

DEAD-box helicase 31

decreases expression

Ketamine results in decreased expression of DDX31 mRNA

NCBI chr 3:12,172,829...12,238,392
Ensembl chr 3:12,172,836...12,238,873

G

defensin beta 1

decreases expression

Ketamine results in decreased expression of DEFB1 mRNA

NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604

G

DENN domain containing 2B

increases expression

Ketamine results in increased expression of DENND2B mRNA

NCBI chr 1:163,544,075...163,734,736
Ensembl chr 1:163,544,074...163,694,680

G

diacylglycerol O-acyltransferase 2

increases expression

Ketamine results in increased expression of DGAT2 mRNA

NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428

G

diacylglycerol kinase, gamma

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of DGKG mRNA

NCBI chr11:78,384,212...78,579,158
Ensembl chr11:78,384,458...78,577,212

G

dihydroorotate dehydrogenase

decreases expression

Ketamine results in decreased expression of DHODH mRNA

NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654

G

DEAH-box helicase 36

decreases expression

Ketamine results in decreased expression of DHX36 mRNA

NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572

G

divergent protein kinase domain 1A

increases expression

Ketamine results in increased expression of DIPK1A mRNA

NCBI chr14:1,772,412...1,843,508
Ensembl chr14:1,772,422...1,843,743

G

discs large MAGUK scaffold protein 4

decreases expression
increases expression
multiple interactions

Ketamine results in decreased expression of DLG4 protein
Ketamine results in increased expression of DLG4 protein
Ketamine inhibits the reaction [Corticosterone results in decreased expression of DLG4 protein]; Sirolimus inhibits the reaction [Ketamine results in increased expression of DLG4 protein]

PMID:31470060 PMID:33022268 PMID:33872575 PMID:36172893

NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153

G

distal-less homeobox 5

decreases expression

Ketamine results in decreased expression of DLX5 mRNA

NCBI chr 4:34,999,139...35,003,504
Ensembl chr 4:34,999,139...35,003,407

G

distal membrane arm assembly component 1

decreases expression

Ketamine results in decreased expression of DMAC1 mRNA

NCBI chr 5:89,241,173...89,243,793
Ensembl chr 5:89,242,661...89,243,757

G

DMRT-like family C1a

increases expression

Ketamine results in increased expression of DMRTC1A mRNA

NCBI chr X:67,822,187...67,852,572
Ensembl chr X:67,822,113...67,852,571

G

cyclin D binding myb-like transcription factor 1

decreases expression

Ketamine results in decreased expression of DMTF1 mRNA

NCBI chr 4:24,909,937...24,950,786
Ensembl chr 4:24,910,534...24,950,967

G

DnaJ heat shock protein family (Hsp40) member B14

decreases expression

Ketamine results in decreased expression of DNAJB14 mRNA

NCBI chr 2:226,358,988...226,409,461
Ensembl chr 2:226,358,996...226,402,490

G

DnaJ heat shock protein family (Hsp40) member C15

decreases expression

Ketamine results in decreased expression of DNAJC15 mRNA

NCBI chr15:53,182,060...53,249,675
Ensembl chr15:53,184,855...53,249,675

G

dynamin 1

increases expression

Ketamine results in increased expression of DNM1 mRNA

NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538

G

DNA methyltransferase 3 beta

decreases expression

Ketamine results in decreased expression of DNMT3B mRNA

NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124

G

dedicator of cytokinesis 11

decreases expression

Ketamine results in decreased expression of DOCK11 mRNA

NCBI chr X:115,131,720...115,314,854
Ensembl chr X:115,131,909...115,314,854

G

diphthamide biosynthesis 5

decreases expression

Ketamine results in decreased expression of DPH5 mRNA

NCBI chr 2:203,804,620...203,858,196
Ensembl chr 2:203,804,936...203,840,433

G

dihydropyrimidinase-like 3

decreases expression

Ketamine results in decreased expression of DPYSL3 mRNA

NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157

G

deltex E3 ubiquitin ligase 4

decreases expression

Ketamine results in decreased expression of DTX4 mRNA

NCBI chr 1:209,457,719...209,545,163
Ensembl chr 1:209,460,735...209,492,818

G

dual specificity phosphatase 11

decreases expression

Ketamine results in decreased expression of DUSP11 mRNA

NCBI chr 4:118,367,673...118,385,183
Ensembl chr 4:118,368,053...118,385,181

G

dual specificity phosphatase 22

increases expression

Ketamine results in increased expression of DUSP22 mRNA

NCBI chr17:33,780,980...33,831,241
Ensembl chr17:33,780,981...33,831,321

G

dual specificity phosphatase 5

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of CPG21 mRNA

NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818

G

dynein 2 intermediate chain 2

decreases expression

Ketamine results in decreased expression of DYNC2I2 mRNA

NCBI chr 3:13,306,039...13,322,121
Ensembl chr 3:13,306,039...13,322,121

G

glutamyl-tRNA synthetase 2, mitochondrial

decreases expression

Ketamine results in decreased expression of EARS2 mRNA

NCBI chr 1:176,597,986...176,625,848
Ensembl chr 1:176,597,986...176,625,836

G

EBP, cholestenol delta-isomerase

decreases expression

Ketamine results in decreased expression of EBP mRNA

NCBI chr X:14,299,427...14,305,826
Ensembl chr X:14,299,448...14,305,826

G

EBP like

decreases expression

Ketamine results in decreased expression of EBPL mRNA

NCBI chr15:35,508,074...35,531,472
Ensembl chr15:35,508,074...35,531,472

G

enoyl-CoA hydratase, short chain 1

increases expression

Ketamine results in increased expression of ECHS1 protein

NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884

G

epithelial cell transforming 2

decreases expression

Ketamine results in decreased expression of ECT2 mRNA

NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911

G

enhancer of mRNA decapping 3

increases expression

Ketamine results in increased expression of EDC3 mRNA

NCBI chr 8:58,106,147...58,151,685
Ensembl chr 8:58,106,175...58,151,671

G

eukaryotic elongation factor-2 kinase

decreases expression

Ketamine results in decreased expression of EEF2K mRNA

NCBI chr 1:175,393,119...175,456,756
Ensembl chr 1:175,393,154...175,455,164

G

EF hand domain family, member B

increases expression

Ketamine results in increased expression of EFHB mRNA

NCBI chr 9:6,372,191...6,441,678
Ensembl chr 9:6,372,194...6,441,919

G

ephrin A2

decreases expression

Ketamine results in decreased expression of EFNA2 mRNA

NCBI chr 7:9,515,635...9,528,071
Ensembl chr 7:9,516,429...9,527,061

G

early growth response 4

decreases expression

Ketamine results in decreased expression of EGR4 mRNA

NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328

G

eukaryotic translation initiation factor 1A

decreases expression

Ketamine results in decreased expression of EIF1A mRNA

NCBI chr18:39,325,695...39,338,043
Ensembl chr18:39,325,202...39,338,696

G

eukaryotic translation initiation factor 4E family member 3

decreases expression

Ketamine results in decreased expression of EIF4E3 mRNA

NCBI chr 4:132,258,502...132,301,808
Ensembl chr 4:132,258,502...132,301,808

G

enolase 2

decreases expression

Ketamine results in decreased expression of ENO2 protein

NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980

G

ectonucleotide pyrophosphatase/phosphodiesterase 2

increases expression

Ketamine results in increased expression of ENPP2 mRNA

NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827

G

endosomal transmembrane epsin interactor 1

increases expression

Ketamine results in increased expression of ENTREP1 mRNA

NCBI chr 1:221,592,500...221,646,603
Ensembl chr 1:221,592,503...221,646,758

G

epoxide hydrolase 4

increases expression

Ketamine results in increased expression of EPHX4 mRNA

NCBI chr14:2,343,376...2,372,680
Ensembl chr14:2,340,248...2,373,022

G

erb-b2 receptor tyrosine kinase 4

decreases expression

Ketamine results in decreased expression of ERBB4 mRNA

NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595

G

glutamate-rich 1

decreases expression

Ketamine results in decreased expression of ERICH1 mRNA

NCBI chr16:75,501,322...75,569,129
Ensembl chr16:75,501,384...75,569,128

G

endoplasmic reticulum metallopeptidase 1

increases expression

Ketamine results in increased expression of ERMP1 mRNA

NCBI chr 1:227,383,992...227,422,120
Ensembl chr 1:227,387,920...227,436,909

G

enhancer of zeste 1 polycomb repressive complex 2 subunit

increases expression

Ketamine results in increased expression of EZH1 mRNA

NCBI chr10:86,126,023...86,162,001
Ensembl chr10:86,126,015...86,161,921

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

decreases expression

Ketamine results in decreased expression of EZH2 mRNA

NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362

G

family with sequence similarity 110, member D

decreases expression

Ketamine results in decreased expression of FAM110D mRNA

NCBI chr 5:146,471,048...146,474,019
Ensembl chr 5:146,471,049...146,474,056

G

family with sequence similarity 120 member B

decreases expression

Ketamine results in decreased expression of FAM120B mRNA

NCBI chr 1:56,320,015...56,385,064
Ensembl chr 1:56,339,129...56,385,061

G

family with sequence similarity 136, member A

decreases expression

Ketamine results in decreased expression of FAM136A mRNA

NCBI chr 4:118,805,129...118,811,046
Ensembl chr 4:118,805,127...118,811,047

G

family with sequence similarity 180, member A

decreases expression

Ketamine results in decreased expression of FAM180A mRNA

NCBI chr 4:63,992,867...64,008,047
Ensembl chr 4:63,992,867...64,008,047

G

family with sequence similarity 210, member A

decreases expression

Ketamine results in decreased expression of FAM210A mRNA

NCBI chr18:61,846,447...61,886,123
Ensembl chr18:61,852,907...61,886,171

G

family with sequence similarity 98, member A

decreases expression

Ketamine results in decreased expression of FAM98A mRNA

NCBI chr 6:19,874,082...19,888,744
Ensembl chr 6:19,874,071...19,888,742

G

FAT atypical cadherin 1

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of FAT1 mRNA

NCBI chr16:47,177,253...47,296,261
Ensembl chr16:47,177,248...47,296,107

G

FAT atypical cadherin 3

decreases expression

Ketamine results in decreased expression of FAT3 mRNA

NCBI chr 8:12,691,470...13,274,336
Ensembl chr 8:12,694,019...13,273,135

G

FAT atypical cadherin 4

decreases expression

Ketamine results in decreased expression of FAT4 mRNA

NCBI chr 2:121,927,266...122,056,700
Ensembl chr 2:121,927,942...122,056,707

G

failed axon connections homolog, metaxin like GST domain containing

increases expression

Ketamine results in increased expression of FAXC mRNA

NCBI chr 5:35,480,137...35,539,741
Ensembl chr 5:35,480,402...35,544,446

G

fibrillarin

decreases expression

Ketamine results in decreased expression of FBL mRNA

NCBI chr 1:83,469,832...83,478,932
Ensembl chr 1:83,469,832...83,478,932

G

filamin binding LIM protein 1

decreases expression

Ketamine results in decreased expression of FBLIM1 mRNA

NCBI chr 5:153,883,945...153,915,524
Ensembl chr 5:153,883,960...153,913,757

G

F-box and leucine-rich repeat protein 22

increases expression

Ketamine results in increased expression of FBXL22 mRNA

NCBI chr 8:67,069,998...67,076,685
Ensembl chr 8:67,069,998...67,076,685

G

F-box protein 2

increases expression

Ketamine results in increased expression of FBXO2 mRNA

NCBI chr 5:158,592,926...158,598,355
Ensembl chr 5:158,592,925...158,598,355

G

F-box protein 34

increases expression

Ketamine results in increased expression of FBXO34 mRNA

NCBI chr15:20,719,395...20,787,905
Ensembl chr15:20,710,629...20,787,222

G

F-box protein 8

increases expression

Ketamine results in increased expression of FBXO8 mRNA

NCBI chr16:33,665,305...33,711,215
Ensembl chr16:33,665,306...33,711,272

G

farnesyl diphosphate farnesyl transferase 1

decreases expression

Ketamine results in decreased expression of FDFT1 mRNA

NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287

G

fem-1 homolog B

increases expression

Ketamine results in increased expression of FEM1B mRNA

NCBI chr 8:63,265,301...63,278,577
Ensembl chr 8:63,265,301...63,278,577

G

fibroblast growth factor receptor 3

increases expression

Ketamine results in increased expression of FGFR3 mRNA

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

G

fibroblast growth factor receptor-like 1

decreases expression

Ketamine results in decreased expression of FGFRL1 mRNA

NCBI chr14:1,009,863...1,022,620
Ensembl chr14:1,009,786...1,021,928

G

FKBP prolyl isomerase family member 15

increases expression

Ketamine results in increased expression of FKBP15 mRNA

NCBI chr 5:75,750,786...75,815,038
Ensembl chr 5:75,750,787...75,814,990

G

fibronectin 1

increases expression
multiple interactions

Ketamine results in increased expression of FN1 protein
2-(5-benzo(1,3)dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride inhibits the reaction [Ketamine results in increased expression of FN1 protein]
Ketamine results in increased expression of FN1 mRNA; Ketamine results in increased expression of FN1 protein

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

G

fructosamine 3 kinase

increases expression

Ketamine results in increased expression of FN3K mRNA

NCBI chr10:106,700,670...106,715,903
Ensembl chr10:106,700,670...106,715,895

G

Fos proto-oncogene, AP-1 transcription factor subunit

multiple interactions

Ketamine inhibits the reaction [Formaldehyde results in increased expression of FOS protein]

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

forkhead box O1

decreases expression

Ketamine results in decreased expression of FOXO1 mRNA

NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790

G

FRAS1 related extracellular matrix 3

increases expression

Ketamine results in increased expression of FREM3 mRNA

NCBI chr19:27,308,469...27,366,771
Ensembl chr19:27,308,469...27,366,771

G

follicle stimulating hormone subunit beta

decreases expression

Ketamine results in decreased expression of FSHB protein

NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370

G

far upstream element binding protein 1

decreases expression

Ketamine results in decreased expression of FUBP1 mRNA

NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602

G

FXYD domain-containing ion transport regulator 1

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of FXYD1 mRNA

NCBI chr 1:86,287,163...86,291,478
Ensembl chr 1:86,287,165...86,291,278

G

FXYD domain-containing ion transport regulator 7

increases expression

Ketamine results in increased expression of FXYD7 mRNA

NCBI chr 1:86,277,678...86,286,954
Ensembl chr 1:86,277,678...86,286,954

G

G0/G1switch 2

decreases expression

Ketamine results in decreased expression of G0S2 mRNA

NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451

G

gamma-aminobutyric acid type A receptor subunit alpha 5

increases expression

Ketamine results in increased expression of GABRA5 mRNA; Ketamine results in increased expression of GABRA5 protein

NCBI chr 1:108,268,728...108,381,670
Ensembl chr 1:108,268,776...108,380,917

G

gamma-aminobutyric acid type A receptor subunit alpha6

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of GABRA6 mRNA

NCBI chr10:26,810,411...26,825,768
Ensembl chr10:26,810,423...26,825,769

G

gamma-aminobutyric acid type A receptor subunit beta 2

decreases expression

Ketamine results in decreased expression of GABRB2 mRNA

NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251

G

gamma-aminobutyric acid type A receptor subunit delta

increases expression
multiple interactions

Ketamine results in increased expression of GABRD mRNA
[ampullosporin co-treated with Ketamine] results in increased expression of GABRD mRNA

PMID:16635253 PMID:20080153

NCBI chr 5:165,958,508...165,970,407
Ensembl chr 5:165,958,484...165,970,411

G

gamma-aminobutyric acid type A receptor subunit gamma 2

decreases expression

Ketamine results in decreased expression of GABRG2 mRNA

NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346

G

glutamate decarboxylase 1

multiple interactions
decreases expression
increases expression

acetovanillone inhibits the reaction [Ketamine results in decreased expression of GAD1 protein]
Ketamine results in increased expression of GAD1 mRNA

PMID:18063801 PMID:23660488

NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333

G

polypeptide N-acetylgalactosaminyltransferase 16

increases expression

Ketamine results in increased expression of GALNT16 mRNA

NCBI chr 6:100,168,943...100,250,718
Ensembl chr 6:100,170,306...100,250,705

G

galanin receptor 2

decreases expression

Ketamine results in decreased expression of GALR2 mRNA

NCBI chr10:101,513,689...101,517,176
Ensembl chr10:101,514,471...101,517,176

G

glyceraldehyde-3-phosphate dehydrogenase, spermatogenic

increases expression

Ketamine results in increased expression of GAPDHS mRNA

NCBI chr 1:85,979,096...85,994,153
Ensembl chr 1:85,979,098...85,993,640

G

golgi associated RAB2 interactor 5A

increases expression

Ketamine results in increased expression of GARIN5A mRNA

NCBI chr 1:94,988,959...94,995,971
Ensembl chr 1:94,988,613...94,993,539

G

GATA zinc finger domain containing 2B

decreases expression

Ketamine results in decreased expression of GATAD2B mRNA

NCBI chr 2:175,748,594...175,829,837
Ensembl chr 2:175,749,433...175,825,542

G

grancalcin

decreases expression

Ketamine results in decreased expression of GCA mRNA

NCBI chr 3:47,297,320...47,329,913
Ensembl chr 3:47,297,383...47,328,581

G

glutamate-cysteine ligase, catalytic subunit

increases expression
decreases expression
multiple interactions

Ketamine results in increased expression of GCLC mRNA
Ketamine results in decreased expression of GCLC mRNA; Ketamine results in decreased expression of GCLC protein
Curcumin inhibits the reaction [Ketamine results in decreased expression of GCLC mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of GCLC protein]

PMID:20080153 PMID:36305173

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

ganglioside-induced differentiation-associated protein 1-like 1

increases expression

Ketamine results in increased expression of GDAP1L1 mRNA

NCBI chr 3:152,110,225...152,129,693
Ensembl chr 3:152,110,253...152,128,711

G

glial fibrillary acidic protein

increases expression

Ketamine results in increased expression of GFAP mRNA

NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589

G

Gfo/Idh/MocA-like oxidoreductase domain containing 2

decreases expression

Ketamine results in decreased expression of GFOD2 mRNA

NCBI chr19:33,599,689...33,647,060
Ensembl chr19:33,604,187...33,647,004

G

glutamine-fructose-6-phosphate transaminase 2

decreases expression

Ketamine results in decreased expression of GFPT2 mRNA

NCBI chr10:34,115,005...34,161,329
Ensembl chr10:34,115,052...34,161,329

G

GDNF family receptor alpha 2

multiple interactions

[ampullosporin co-treated with Ketamine] results in decreased expression of GFRA2 mRNA

NCBI chr15:45,941,841...46,033,715
Ensembl chr15:45,941,828...46,033,714

G

gamma-glutamylamine cyclotransferase

increases expression

Ketamine results in increased expression of GGACT mRNA

NCBI chr15:99,969,246...99,998,343
Ensembl chr15:99,968,282...99,993,455

G

gap junction protein, beta 6

increases expression

Ketamine results in increased expression of GJB6 mRNA

NCBI chr15:31,284,561...31,294,552
Ensembl chr15:31,284,419...31,294,582

G

glutamate-ammonia ligase

increases expression
multiple interactions

Ketamine results in increased expression of GLUL protein
[Guanosine co-treated with Ketamine] results in increased activity of GLUL protein

PMID:18504422 PMID:36878458

NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108

G

G protein-coupled receptor 22

increases expression

Ketamine results in increased expression of GPR22 mRNA

NCBI chr 6:48,309,619...48,317,864
Ensembl chr 6:48,310,505...48,317,486

G

G protein-coupled receptor 37-like 1

increases expression

Ketamine results in increased expression of GPR37L1 mRNA

NCBI chr13:46,598,574...46,605,421
Ensembl chr13:46,598,578...46,605,421

G

G protein-coupled receptor 84

multiple interactions
decreases expression

Cannabidiol inhibits the reaction [Ketamine results in decreased expression of GPR84 mRNA]

NCBI chr 7:134,443,904...134,446,173
Ensembl chr 7:134,443,936...134,446,178

G

G protein-coupled receptor 85

decreases expression

Ketamine results in decreased expression of GPR85 mRNA

NCBI chr 4:42,100,138...42,109,584
Ensembl chr 4:42,102,941...42,109,566

G

glutamate ionotropic receptor AMPA type subunit 1

decreases expression
multiple interactions
increases expression

Ketamine results in decreased expression of GRIA1 protein
Ketamine inhibits the reaction [Corticosterone results in decreased expression of GRIA1 protein]; MAPT protein affects the reaction [Ketamine results in decreased expression of GRIA1 protein]
Ketamine promotes the reaction [Methamphetamine increases expression of Gria1 protein in hippocampus, striatum]
Ketamine increases expression of Gria1 protein on hippocampal formation, prefrontal cortex cell surface

CTD
RGD

PMID:31470060 PMID:33872575 PMID:37778205 PMID:23303054

RGD:405100237, RGD:405650674

NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283

G

glutamate ionotropic receptor AMPA type subunit 2

multiple interactions
decreases expression

MAPT protein affects the reaction [Ketamine results in decreased expression of GRIA2 protein]

NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510

G

glutamate ionotropic receptor delta type subunit 2

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of GRID2 mRNA

NCBI chr 4:92,415,019...93,892,472
Ensembl chr 4:92,415,230...93,889,355

G

glutamate ionotropic receptor kainate type subunit 5

increases expression

Ketamine results in increased expression of GRIK5 mRNA

NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125

G

glutamate ionotropic receptor NMDA type subunit 1

increases expression

Ketamine results in increased expression of GRIN1 mRNA; Ketamine results in increased expression of GRIN1 protein

PMID:19126600 PMID:20080153 PMID:23065140

NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603

G

glutamate ionotropic receptor NMDA type subunit 2A

affects response to substance
increases expression

GRIN2A protein affects the susceptibility to Ketamine
Ketamine results in increased expression of GRIN2A mRNA

PMID:15731593 PMID:20080153

NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637

G

glutamate ionotropic receptor NMDA type subunit 2B

multiple interactions
decreases expression

Ketamine inhibits the reaction [remifentanil results in increased phosphorylation of GRIN2B protein]
Ketamine results in decreased expression of GRIN2B protein

PMID:20042082 PMID:36172893

NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279

G

glutamate ionotropic receptor NMDA type subunit 2C

increases expression

Ketamine results in increased expression of GRIN2C mRNA

NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427

G

glutamate metabotropic receptor 1

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of GRM1 mRNA

NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170

G

glutamate metabotropic receptor 3

decreases expression

Ketamine results in decreased expression of GRM3 mRNA

NCBI chr 4:24,364,854...24,643,972
Ensembl chr 4:24,365,115...24,609,804

G

glutamate metabotropic receptor 4

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of GRM4 mRNA

NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821

G

glycogen synthase kinase 3 beta

decreases phosphorylation
increases phosphorylation
multiple interactions

Ketamine results in decreased phosphorylation of GSK3B protein
Ketamine results in increased phosphorylation of GSK3B protein
Chir 99021 inhibits the reaction [Ketamine results in increased phosphorylation of GSK3B protein]

PMID:17952604 PMID:36334642

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

G

glutathione S-transferase omega 2

increases expression

Ketamine results in increased expression of GSTO2 mRNA

NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866

G

general transcription factor IIH subunit 3

decreases expression

Ketamine results in decreased expression of GTF2H3 mRNA

NCBI chr12:32,009,010...32,025,484
Ensembl chr12:32,009,014...32,025,497

G

GTF2I repeat domain containing 1

increases expression

Ketamine results in increased expression of GTF2IRD1 mRNA

NCBI chr12:22,254,113...22,361,052
Ensembl chr12:22,254,221...22,361,040

G

guanylate cyclase 1 soluble subunit beta 1

decreases expression

Ketamine results in decreased expression of GUCY1B1 mRNA

NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916

G

H1.0 linker histone

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of H1F0 mRNA

NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694

G

H1.4 linker histone, cluster member

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of H1F4 mRNA

NCBI chr17:41,486,574...41,487,355
Ensembl chr17:41,486,560...41,487,403

G

hyaluronan binding protein 4

increases expression

Ketamine results in increased expression of HABP4 mRNA

NCBI chr17:934,931...957,604
Ensembl chr17:935,654...957,565

G

3-hydroxyacyl-CoA dehydratase 3

decreases expression

Ketamine results in decreased expression of HACD3 mRNA

NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507

G

huntingtin-associated protein 1

increases expression

Ketamine results in increased expression of HAP1 mRNA

NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126

G

HAUS augmin-like complex, subunit 8

decreases expression

Ketamine results in decreased expression of HAUS8 mRNA

NCBI chr16:17,930,819...17,945,254
Ensembl chr16:17,930,820...17,945,237

G

hepatitis A virus cellular receptor 1

multiple interactions

[Ketamine co-treated with Xylazine] results in increased secretion of HAVCR1 protein

NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698

G

hemoglobin subunit beta

decreases expression

Ketamine results in decreased expression of HBB-B1 mRNA

NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012

G

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1

decreases expression

Ketamine results in decreased expression of HECW1 mRNA

NCBI chr17:50,671,239...51,084,536
Ensembl chr17:50,670,954...51,080,720

G

hes family bHLH transcription factor 5

decreases expression

Ketamine results in decreased expression of HES5 mRNA

NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001

G

hes family bHLH transcription factor 6

decreases expression

Ketamine results in decreased expression of HES6 mRNA

NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559

G

hexosaminidase subunit beta

decreases expression

Ketamine results in decreased expression of HEXB mRNA

NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223

G

3-hydroxyisobutyryl-CoA hydrolase

decreases expression

Ketamine results in decreased expression of HIBCH mRNA

NCBI chr 9:48,590,097...48,669,896
Ensembl chr 9:48,590,099...48,669,824

G

3-hydroxy-3-methylglutaryl-CoA lyase like 1

decreases expression

Ketamine results in decreased expression of HMGCLL1 mRNA

NCBI chr 8:76,757,301...76,887,300
Ensembl chr 8:76,757,497...76,886,816

G

3-hydroxy-3-methylglutaryl-CoA reductase

decreases expression

Ketamine results in decreased expression of HMGCR mRNA

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

increases expression

Ketamine results in increased expression of HMGCS2 mRNA

NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130

G

high mobility group nucleosome binding domain 1

decreases expression

Ketamine results in decreased expression of HMGN1 mRNA

NCBI chr11:35,422,328...35,428,247
Ensembl chr11:35,422,328...35,428,254

G

high mobility group nucleosomal binding domain 3

increases expression

Ketamine results in increased expression of HMGN3 mRNA

NCBI chr 8:84,022,493...84,059,329
Ensembl chr 8:84,022,495...84,062,976

G

heme oxygenase 1

decreases expression
multiple interactions

Ketamine results in decreased expression of HMOX1 mRNA; Ketamine results in decreased expression of HMOX1 protein
Curcumin inhibits the reaction [Ketamine results in decreased expression of HMOX1 mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of HMOX1 protein]

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

heme oxygenase 2

increases expression

Ketamine results in increased expression of HMOX2 mRNA

NCBI chr10:10,797,076...10,831,178
Ensembl chr10:10,797,055...10,831,148

G

heterogeneous nuclear ribonucleoprotein A2/B1

increases expression

Ketamine results in increased expression of HNRNPA2B1 protein

NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249

G

heterogeneous nuclear ribonucleoprotein H3

decreases expression

Ketamine results in decreased expression of HNRNPH3 mRNA

NCBI chr20:25,616,400...25,625,814
Ensembl chr20:25,614,733...25,625,750

G

HOP homeobox

increases expression

Ketamine results in increased expression of HOPX mRNA

NCBI chr14:31,055,912...31,082,909
Ensembl chr14:31,075,148...31,082,909

G

hippocalcin

increases expression

Ketamine results in increased expression of HPCA mRNA

NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841

G

hippocalcin-like 1

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of HPCAL1 mRNA

NCBI chr 6:40,478,206...40,584,721
Ensembl chr 6:40,478,208...40,584,687

G

4-hydroxyphenylpyruvate dioxygenase-like

decreases expression

Ketamine results in decreased expression of HPDL mRNA

NCBI chr 5:130,286,627...130,288,233
Ensembl chr 5:130,286,631...130,288,233

G

15-hydroxyprostaglandin dehydrogenase

decreases expression

Ketamine results in decreased expression of HPGD mRNA

NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228

G

HRas proto-oncogene, GTPase

multiple interactions

Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of HRAS protein]

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

histamine receptor H3

increases expression

Ketamine results in increased expression of HRH3 mRNA

NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642

G

harakiri, BCL2 interacting protein

increases expression

Ketamine results in increased expression of HRK mRNA

NCBI chr12:38,387,484...38,409,652

G

heparan sulfate-glucosamine 3-sulfotransferase 5

decreases expression

Ketamine results in decreased expression of HS3ST5 mRNA

NCBI chr20:40,106,876...40,417,661
Ensembl chr20:40,106,876...40,417,653

G

hydroxysteroid 11-beta dehydrogenase 1

increases expression

Ketamine results in increased expression of HSD11B1 mRNA

NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687

G

hydroxysteroid (17-beta) dehydrogenase 4

decreases expression

Ketamine results in decreased expression of HSD17B4 mRNA

NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952

G

heat shock protein family A (Hsp70) member 2

increases expression

Ketamine results in increased expression of HSPA2 mRNA

NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287

G

heat shock protein family A (Hsp70) member 5

decreases expression
affects expression
multiple interactions
increases expression

Ketamine results in decreased expression of HSPA5 mRNA
Ketamine affects the expression of HSPA5 mRNA
LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of HSPA5 protein]]; lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of HSPA5 protein]

PMID:20080153 PMID:35728656 PMID:36907275

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

HtrA serine peptidase 1

increases expression

Ketamine results in increased expression of HTRA1 mRNA

NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379

G

intercellular adhesion molecule 1

multiple interactions

[Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 protein]

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

intercellular adhesion molecule 5

increases expression

Ketamine results in increased expression of ICAM5 mRNA

NCBI chr 8:19,567,390...19,575,588
Ensembl chr 8:19,568,600...19,575,588

G

isocitrate dehydrogenase (NADP(+)) 1

decreases expression

Ketamine results in decreased expression of IDH1 mRNA

NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708

G

isopentenyl-diphosphate delta isomerase 1

decreases expression

Ketamine results in decreased expression of IDI1 mRNA

NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357

G

interferon, alpha-inducible protein 27

increases expression

Ketamine results in increased expression of IFI27 mRNA

NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294

G

interferon, alpha-inducible protein 27 like 2A

increases expression

Ketamine results in increased expression of IFI27L1 mRNA

NCBI chr 6:122,598,872...122,600,358
Ensembl chr 6:122,598,872...122,600,360

G

interferon induced transmembrane protein 10

increases expression

Ketamine results in increased expression of IFITM10 mRNA

NCBI chr 1:197,507,501...197,524,180
Ensembl chr 1:197,507,503...197,525,151

G

interferon gamma receptor 1

increases expression

Ketamine results in increased expression of IFNGR1 mRNA

NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785

G

interferon gamma receptor 2

increases expression

Ketamine results in increased expression of IFNGR2 mRNA

NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005

G

insulin-like growth factor 2

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of IGF2 mRNA

NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018

G

insulin-like growth factor binding protein 1

increases expression

Ketamine results in increased expression of IGFBP1 mRNA

NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482

G

insulin-like growth factor binding protein 2

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of IGFBP2 mRNA

NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937

G

insulin-like growth factor binding protein 3

increases expression

Ketamine results in increased expression of IGFBP3 mRNA

NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083

G

insulin-like growth factor binding protein-like 1

decreases expression

Ketamine results in decreased expression of IGFBPL1 mRNA

NCBI chr 5:60,076,428...60,091,833
Ensembl chr 5:60,076,429...60,091,833

G

immunoglobulin superfamily, member 9

decreases expression

Ketamine results in decreased expression of IGSF9 mRNA

NCBI chr13:84,948,643...84,965,616
Ensembl chr13:84,948,619...84,965,607

G

IKBKB interacting protein

decreases expression

Ketamine results in decreased expression of IKBIP mRNA

NCBI chr 7:25,579,865...25,598,548
Ensembl chr 7:25,579,832...25,605,162

G

interleukin 12A

increases expression

Ketamine results in increased expression of IL12A mRNA

NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734

G

interleukin 1 beta

increases expression
multiple interactions
increases secretion

Ketamine results in increased expression of IL1B mRNA; Ketamine results in increased expression of IL1B protein
Ozone inhibits the reaction [Ketamine results in increased expression of IL1B mRNA]; TRPV4 protein affects the reaction [Ketamine results in increased expression of IL1B protein]
[Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B protein]; Ketamine inhibits the reaction [Acetaminophen results in increased expression of IL1B protein]; Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; TLR4 mutant form promotes the reaction [Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; TLR4 mutant form promotes the reaction [Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]
Ketamine results in increased secretion of IL1B protein

PMID:15207037 PMID:15207038 PMID:19540866 PMID:22245128 PMID:33536391 More...

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

multiple interactions
affects response to substance
increases expression

Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
IL6 affects the susceptibility to Ketamine
Ketamine results in increased expression of IL6 mRNA; Ketamine results in increased expression of IL6 protein
[Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 mRNA]; [Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 protein]; Ketamine inhibits the reaction [Acetaminophen results in increased expression of IL6 protein]; Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; mangiferin inhibits the reaction [Ketamine results in increased expression of IL6 protein]
TRPV4 protein affects the reaction [Ketamine results in increased expression of IL6 protein]

PMID:15207037 PMID:15207038 PMID:15720977 PMID:19091984 PMID:19540866 More...

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

internexin neuronal intermediate filament protein, alpha

increases expression

Ketamine results in increased expression of INA protein

NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330

G

inhibitor of growth family, member 2

increases expression

Ketamine results in increased expression of ING2 mRNA

NCBI chr16:44,573,592...44,584,180
Ensembl chr16:44,575,597...44,583,482

G

inhibin subunit beta A

decreases expression

Ketamine results in decreased expression of INHBA mRNA

NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982

G

INO80 complex subunit C

increases expression

Ketamine results in increased expression of INO80C mRNA

NCBI chr18:15,378,764...15,398,574
Ensembl chr18:15,378,770...15,393,403

G

inositol polyphosphate-5-phosphatase D

increases expression

Ketamine results in increased expression of INPP5D mRNA

NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746

G

inositol polyphosphate-5-phosphatase F

decreases expression

Ketamine results in decreased expression of INPP5F mRNA

NCBI chr 1:183,190,480...183,270,276
Ensembl chr 1:183,190,480...183,270,276

G

integrator complex subunit 3

decreases expression

Ketamine results in decreased expression of INTS3 mRNA

NCBI chr 2:175,859,421...175,911,683
Ensembl chr 2:175,859,440...175,911,709

G

inositol-3-phosphate synthase 1

decreases expression

Ketamine results in decreased expression of ISYNA1 mRNA

NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979

G

inter-alpha trypsin inhibitor, heavy chain 3

increases expression

Ketamine results in increased expression of ITIH3 mRNA

NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924

G

integral membrane protein 2C

increases expression

Ketamine results in increased expression of ITM2C mRNA

NCBI chr 9:86,545,927...86,559,745
Ensembl chr 9:86,545,921...86,559,742

G

inositol-trisphosphate 3-kinase A

increases expression

Ketamine results in increased expression of ITPKA mRNA

NCBI chr 3:106,726,036...106,734,601
Ensembl chr 3:106,726,036...106,734,600

G

influenza virus NS1A binding protein

decreases expression

Ketamine results in decreased expression of IVNS1ABP mRNA

NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701

G

jade family PHD finger 3

decreases expression

Ketamine results in decreased expression of JADE3 mRNA

NCBI chr X:1,668,873...1,848,781
Ensembl chr X:1,669,930...1,845,138

G

jagged canonical Notch ligand 2

decreases expression

Ketamine results in decreased expression of JAG2 mRNA

NCBI chr 6:131,983,059...132,005,665
Ensembl chr 6:131,983,056...132,005,818

G

Janus kinase 2

decreases expression

Ketamine results in decreased expression of JAK2 mRNA

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

G

jumonji domain containing 1C

decreases expression

Ketamine results in decreased expression of JMJD1C mRNA

NCBI chr20:21,332,147...21,494,220
Ensembl chr20:21,332,147...21,463,122

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression

Ketamine results in increased expression of JUN mRNA

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

Kazal-type serine peptidase inhibitor domain 1

increases expression

Ketamine results in increased expression of KAZALD1 mRNA

NCBI chr 1:243,939,596...243,943,060
Ensembl chr 1:243,939,647...243,943,059

G

kazrin, periplakin interacting protein

increases expression

Ketamine results in increased expression of KAZN mRNA

NCBI chr 5:154,392,793...155,381,567
Ensembl chr 5:154,392,793...154,779,074

G

potassium voltage-gated channel subfamily C member 1

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of KCNC1 mRNA

NCBI chr 1:96,902,953...96,944,744
Ensembl chr 1:96,902,953...96,944,744

G

potassium voltage-gated channel subfamily C member 2

decreases expression

Ketamine results in decreased expression of KCNC2 mRNA

NCBI chr 7:47,700,035...47,883,979
Ensembl chr 7:47,700,288...47,883,968

G

potassium voltage-gated channel modifier subfamily G member 1

decreases expression

Ketamine results in decreased expression of KCNG1 mRNA

NCBI chr 3:156,960,717...156,992,877
Ensembl chr 3:156,973,156...156,992,635

G

potassium voltage-gated channel interacting protein 2

increases expression

Ketamine results in increased expression of KCNIP2 mRNA

NCBI chr 1:244,641,147...244,664,939
Ensembl chr 1:244,641,150...244,664,874

G

potassium inwardly-rectifying channel, subfamily J, member 12

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of KCNJ12 mRNA

NCBI chr10:45,696,621...45,745,528
Ensembl chr10:45,696,849...45,745,492

G

potassium inwardly-rectifying channel, subfamily J, member 14

decreases expression

Ketamine results in decreased expression of KCNJ14 mRNA

NCBI chr 1:96,293,159...96,300,810
Ensembl chr 1:96,293,435...96,495,459

G

potassium calcium-activated channel subfamily M regulatory beta subunit 4

multiple interactions

[ampullosporin co-treated with Ketamine] results in decreased expression of KCNMB4 mRNA

NCBI chr 7:52,066,145...52,119,098
Ensembl chr 7:52,066,136...52,119,278

G

potassium voltage-gated channel, modifier subfamily S, member 3

decreases expression

Ketamine results in decreased expression of KCNS3 mRNA

NCBI chr 6:33,808,314...33,865,018
Ensembl chr 6:33,808,216...33,865,125

G

KIAA0319 homolog

decreases expression

Ketamine results in decreased expression of KIAA0319 mRNA

NCBI chr17:40,162,512...40,226,666
Ensembl chr17:40,165,084...40,225,653

G

kinesin family member 11

decreases expression

Ketamine results in decreased expression of KIF11 mRNA

NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766

G

kinesin family member 13A

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of KIF13A mRNA

NCBI chr17:17,766,597...17,948,517
Ensembl chr17:17,766,597...17,943,615

G

kinesin family member 20A

decreases expression

Ketamine results in decreased expression of KIF20A mRNA

NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780

G

kinesin family member C2

multiple interactions

[ampullosporin co-treated with Ketamine] results in decreased expression of KIFC2 mRNA

NCBI chr 7:108,380,634...108,388,364
Ensembl chr 7:108,376,011...108,388,484

G

KLF transcription factor 15

increases expression

Ketamine results in increased expression of KLF15 mRNA

NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374

G

KLF transcription factor 6

decreases expression

Ketamine results in decreased expression of KLF6 mRNA

NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570

G

KLF transcription factor 9

increases expression

Ketamine results in increased expression of KLF9 mRNA

NCBI chr 1:220,700,108...220,725,110
Ensembl chr 1:220,700,108...220,725,037

G

kelch domain containing 1

decreases expression

Ketamine results in decreased expression of KLHDC1 mRNA

NCBI chr 6:87,670,182...87,765,431
Ensembl chr 6:87,712,772...87,765,424

G

kelch domain containing 9

increases expression

Ketamine results in increased expression of KLHDC9 mRNA

NCBI chr13:83,790,390...83,794,080
Ensembl chr13:83,790,269...83,793,354

G

kelch-like family member 24

decreases expression

Ketamine results in decreased expression of KLHL24 mRNA

NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636

G

kelch-like family member 7

decreases expression

Ketamine results in decreased expression of KLHL7 mRNA

NCBI chr 4:11,006,366...11,055,399
Ensembl chr 4:11,006,375...11,055,541

G

kelch-like family member 8

decreases expression

Ketamine results in decreased expression of KLHL8 mRNA

NCBI chr14:5,807,795...5,853,325
Ensembl chr14:5,807,907...5,853,294

G

kelch-like family member 9

decreases expression

Ketamine results in decreased expression of KLHL9 mRNA

NCBI chr 5:103,333,747...103,337,931

G

kallikrein related-peptidase 6

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of KLK6 mRNA

NCBI chr 1:94,278,863...94,286,136
Ensembl chr 1:94,280,340...94,286,121

G

lysine methyltransferase 5A

decreases expression

Ketamine results in decreased expression of KMT5A mRNA

NCBI chr12:32,139,353...32,167,777
Ensembl chr12:32,139,178...32,162,711

G

kininogen 1

multiple interactions

Ketamine inhibits the reaction [KNG1 protein results in increased expression of OCLN protein]

NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555

G

kinetochore-localized astrin/SPAG5 binding protein

decreases expression

Ketamine results in decreased expression of KNSTRN mRNA

NCBI chr 3:105,800,762...105,820,555
Ensembl chr 3:105,800,954...105,820,715

G

karyopherin subunit alpha 2

decreases expression

Ketamine results in decreased expression of KPNA2 mRNA

NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150

G

karyopherin subunit beta 1

decreases expression

Ketamine results in decreased expression of KPNB1 mRNA

NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605

G

kinectin 1

decreases expression

Ketamine results in decreased expression of KTN1 mRNA

NCBI chr15:20,913,665...21,002,588
Ensembl chr15:20,914,642...21,002,578

G

laminin subunit beta 1

decreases expression

Ketamine results in decreased expression of LAMB1 mRNA

NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585

G

lysosomal-associated membrane protein family, member 5

increases expression

Ketamine results in increased expression of LAMP5 mRNA

NCBI chr 3:123,372,462...123,384,973
Ensembl chr 3:123,372,462...123,384,952

G

lysosomal protein transmembrane 4 beta

increases expression

Ketamine results in increased expression of LAPTM4B mRNA

NCBI chr 7:65,434,525...65,477,386
Ensembl chr 7:65,434,394...65,477,383

G

lysosomal protein transmembrane 5

increases expression

Ketamine results in increased expression of LAPTM5 mRNA

NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807

G

lipopolysaccharide binding protein

multiple interactions

Ketamine inhibits the reaction [Lipopolysaccharides binds to LBP protein]

NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586

G

lipocalin 2

multiple interactions

[Ketamine co-treated with Xylazine] results in decreased secretion of LCN2 protein

NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095

G

lactate dehydrogenase B

decreases expression

Ketamine results in decreased expression of LDHB protein

NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403

G

leukocyte receptor cluster member 8

decreases expression

Ketamine results in decreased expression of LENG8 mRNA

NCBI chr 1:70,040,785...70,052,662
Ensembl chr 1:70,040,785...70,052,488

G

leptin

multiple interactions
decreases expression

LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in decreased expression of BCL2 protein]]; LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased cleavage of CASP3 protein]]; LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of DDIT3 protein]]; LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of HSPA5 protein]]; lipoxin A4 methyl ester inhibits the reaction [Ketamine results in decreased expression of LEP protein]

NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262

G

leptin receptor

multiple interactions
decreases expression

lipoxin A4 methyl ester inhibits the reaction [Ketamine results in decreased expression of LEPR protein]

NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908

G

galectin 1

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of LGALS1 mRNA

NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345

G

galectin 3 binding protein

increases expression

Ketamine results in increased expression of LGALS3BP mRNA

NCBI chr10:103,619,912...103,629,251
Ensembl chr10:103,619,908...103,629,256

G

leucine-rich repeat LGI family, member 4

increases expression

Ketamine results in increased expression of LGI4 mRNA

NCBI chr 1:86,294,539...86,305,909
Ensembl chr 1:86,295,074...86,304,874

G

luteinizing hormone subunit beta

decreases expression

Ketamine results in decreased expression of LHB protein

NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972

G

lin-7 homolog B, crumbs cell polarity complex component

increases expression

Ketamine results in increased expression of LIN7B mRNA

NCBI chr 1:95,846,888...95,849,628
Ensembl chr 1:95,846,243...95,849,977

G

limb and CNS expressed 1 like

decreases expression

Ketamine results in decreased expression of LIX1L mRNA

NCBI chr 2:184,136,018...184,161,918
Ensembl chr 2:184,136,038...184,161,916

G

limb development membrane protein 1

increases expression

Ketamine results in increased expression of LMBR1 mRNA

NCBI chr 4:5,974,687...6,146,348
Ensembl chr 4:5,974,750...6,146,368

G

LIM and cysteine-rich domains 1

increases expression

Ketamine results in increased expression of LMCD1 mRNA

NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046

G

LDL receptor related protein associated protein 1

increases expression

Ketamine results in increased expression of LRPAP1 mRNA

NCBI chr14:75,651,371...75,663,380
Ensembl chr14:75,651,376...75,665,414

G

leucine rich repeat containing 42

decreases expression

Ketamine results in decreased expression of LRRC42 mRNA

NCBI chr 5:122,014,678...122,035,792
Ensembl chr 5:122,014,678...122,035,829

G

leucine rich repeat containing 55

decreases expression

Ketamine results in decreased expression of LRRC55 mRNA

NCBI chr 3:70,269,908...70,280,651
Ensembl chr 3:70,265,936...70,278,639

G

LSM10, U7 small nuclear RNA associated

decreases expression

Ketamine results in decreased expression of LSM10 mRNA

NCBI chr 5:138,365,983...138,375,856
Ensembl chr 5:138,373,119...138,377,505

G

LUC7-like

decreases expression

Ketamine results in decreased expression of LUC7L mRNA

NCBI chr10:15,273,340...15,307,131
Ensembl chr10:15,273,348...15,303,112

G

Ly6/Plaur domain containing 3

decreases expression

Ketamine results in decreased expression of LYPD3 mRNA

NCBI chr 1:80,226,449...80,230,901
Ensembl chr 1:80,226,449...80,230,901

G

leucine zipper tumor suppressor 1

multiple interactions

[ampullosporin co-treated with Ketamine] results in decreased expression of LZTS1 mRNA

NCBI chr16:20,542,756...20,598,204
Ensembl chr16:20,542,809...20,598,203

G

mab-21 like 2

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of MAB21L2 mRNA

NCBI chr 2:171,946,573...171,949,655
Ensembl chr 2:171,946,573...171,949,655

G

mal, T-cell differentiation protein

increases expression

Ketamine results in increased expression of MAL mRNA

NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136

G

mannosidase, alpha, class 2B, member 1

increases expression

Ketamine results in increased expression of MAN2B1 mRNA

NCBI chr19:23,055,092...23,074,398
Ensembl chr19:23,055,097...23,074,389

G

mesencephalic astrocyte-derived neurotrophic factor

decreases expression

Ketamine results in decreased expression of MANF mRNA

PMID:20080153 PMID:35728656

NCBI chr 8:107,500,856...107,551,595
Ensembl chr 8:107,548,352...107,551,438

G

microtubule-associated protein 1B

decreases expression

Ketamine results in decreased expression of MAP1B mRNA

NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317

G

mitogen activated protein kinase kinase 1

multiple interactions

Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAP2K1 protein]

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

G

mitogen activated protein kinase kinase 2

multiple interactions

Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAP2K2 protein]

NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243

G

microtubule-associated protein 6

increases expression

Ketamine results in increased expression of MAP6 mRNA

NCBI chr 1:153,568,020...153,634,415
Ensembl chr 1:153,568,368...153,634,414

G

mitogen activated protein kinase 1

multiple interactions

Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

multiple interactions

Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

mitogen-activated protein kinase 7

decreases expression

Ketamine results in decreased expression of MAPK7 mRNA

NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267

G

microtubule-associated protein tau

increases phosphorylation
multiple interactions

Ketamine results in increased phosphorylation of MAPT protein
MAPT protein affects the reaction [Ketamine results in decreased expression of GRIA1 protein]; MAPT protein affects the reaction [Ketamine results in decreased expression of GRIA2 protein]

PMID:20093173 PMID:31470060

NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129

G

meiosis regulator and mRNA stability factor 1

decreases expression

Ketamine results in decreased expression of MARF1 mRNA

NCBI chr10:888,053...932,760
Ensembl chr10:888,076...932,753

G

MAS1 proto-oncogene, G protein-coupled receptor

decreases expression

Ketamine results in decreased expression of MAS1 mRNA

NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709

G

megakaryocyte-associated tyrosine kinase

increases expression

Ketamine results in increased expression of MATK mRNA

NCBI chr 7:8,456,990...8,465,947
Ensembl chr 7:8,456,998...8,462,022

G

mitochondrial antiviral signaling protein

decreases expression

Ketamine results in decreased expression of MAVS mRNA

NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094

G

myelin basic protein

increases expression

Ketamine results in increased expression of MBP mRNA

NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404

G

minichromosome maintenance complex component 3

decreases expression

Ketamine results in decreased expression of MCM3 mRNA

NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314

G

mitochondrial calcium uniporter

decreases expression

Ketamine results in decreased expression of MCU mRNA

NCBI chr20:27,417,529...27,580,110
Ensembl chr20:27,417,526...27,580,110

G

methyltransferase 16, RNA N6-adenosine

decreases expression

Ketamine results in decreased expression of METTL16 mRNA

NCBI chr10:59,640,915...59,697,291
Ensembl chr10:59,640,972...59,687,061

G

methyltransferase like 25B

increases expression

Ketamine results in increased expression of METTL25B mRNA

NCBI chr 2:173,388,625...173,397,279
Ensembl chr 2:173,388,625...173,397,279

G

methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit

decreases expression

Ketamine results in decreased expression of METTL3 mRNA

NCBI chr15:25,002,505...25,014,097
Ensembl chr15:25,003,172...25,014,041

G

MFSD2 lysolipid transporter A, lysophospholipid

increases expression

Ketamine results in increased expression of MFSD2A mRNA

NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690

G

microsomal glutathione S-transferase 2

increases expression

Ketamine results in increased expression of MGST2 mRNA

NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828

G

microsomal glutathione S-transferase 3 like 1

increases expression

Ketamine results in increased expression of MGST3L1 mRNA

NCBI chr14:19,525,509...19,526,128
Ensembl chr14:19,525,558...19,526,016

G

MIB E3 ubiquitin protein ligase 1

increases expression

Ketamine results in increased expression of MIB1 mRNA

NCBI chr18:1,802,519...1,926,988
Ensembl chr18:1,802,519...1,920,689

G

microtubule associated monooxygenase, calponin and LIM domain containing 1

decreases expression

Ketamine results in decreased expression of MICAL1 mRNA

NCBI chr20:44,974,137...44,986,089
Ensembl chr20:44,974,138...44,986,089

G

MIF4G domain containing

increases expression

Ketamine results in increased expression of MIF4GD mRNA

NCBI chr10:100,847,168...100,852,166

G

microRNA 22

decreases expression
multiple interactions

Ketamine results in decreased expression of MIR22 mRNA
lipoxin A4 methyl ester inhibits the reaction [Ketamine results in decreased expression of MIR22 mRNA]; MIR22 affects the reaction [Ketamine results in increased expression of BAG5 mRNA]; MIR22 affects the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of BAG5 protein]]; MIR22 affects the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of CASP3 mRNA]]; MIR22 inhibits the reaction [Ketamine results in increased activity of CASP3 protein]; MIR22 inhibits the reaction [Ketamine results in increased activity of CASP9 protein]; MIR22 inhibits the reaction [Ketamine results in increased expression of BAG5 protein]

NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133

G

MIS12 kinetochore complex component

decreases expression

Ketamine results in decreased expression of MIS12 mRNA

NCBI chr10:55,739,741...55,747,915
Ensembl chr10:55,739,564...55,751,068

G

MIS18 kinetochore protein A

decreases expression

Ketamine results in decreased expression of MIS18A mRNA

NCBI chr11:29,968,030...29,981,058
Ensembl chr11:29,967,701...29,981,062

G

marker of proliferation Ki-67

increases expression

Ketamine results in increased expression of MKI67 protein

NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762

G

MKKS centrosomal shuttling protein

decreases expression

Ketamine results in decreased expression of MKKS mRNA

NCBI chr 3:124,201,877...124,221,142
Ensembl chr 3:124,201,877...124,220,162

G

MLLT3, super elongation complex subunit

decreases expression

Ketamine results in decreased expression of MLLT3 mRNA

NCBI chr 5:102,259,075...102,515,447
Ensembl chr 5:102,260,011...102,515,361

G

monocyte to macrophage differentiation-associated 2

increases expression

Ketamine results in increased expression of MMD2 mRNA

NCBI chr12:11,962,733...12,009,776
Ensembl chr12:11,962,757...12,009,773

G

matrix metallopeptidase 14

decreases expression

Ketamine results in decreased expression of MMP14 mRNA

NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864

G

myelin oligodendrocyte glycoprotein

increases expression

Ketamine results in increased expression of MOG mRNA

NCBI chr20:1,513,137...1,523,473
Ensembl chr20:1,513,239...1,523,474

G

MON1 homolog A, secretory trafficking associated

decreases expression

Ketamine results in decreased expression of MON1A mRNA

NCBI chr 8:108,574,272...108,593,163
Ensembl chr 8:108,574,388...108,593,156

G

MORN repeat containing 2

increases expression

Ketamine results in increased expression of MORN2 mRNA

NCBI chr 6:14,718,799...14,725,281

G

muscle RAS oncogene homolog

increases expression

Ketamine results in increased expression of MRAS mRNA

NCBI chr 8:99,944,036...100,006,771
Ensembl chr 8:99,944,036...99,996,408

G

mitochondrial ribosomal protein L18

decreases expression

Ketamine results in decreased expression of MRPL18 mRNA

NCBI chr 1:47,837,169...47,841,987
Ensembl chr 1:47,836,561...47,841,987

G

mitochondrial ribosomal protein L50

decreases expression

Ketamine results in decreased expression of MRPL50 mRNA

NCBI chr 5:63,867,437...63,872,591

G

mitochondrial ribosomal protein S15

increases expression

Ketamine results in increased expression of MRPS15 mRNA

NCBI chr 5:138,321,610...138,332,205
Ensembl chr 5:138,321,593...138,332,205

G

membrane spanning 4-domains A6A

increases expression

Ketamine results in increased expression of MS4A6A mRNA

NCBI chr 1:208,401,465...208,414,831
Ensembl chr 1:208,401,466...208,414,758

G

Myb/SANT DNA binding domain containing 3

increases expression

Ketamine results in increased expression of MSANTD3 mRNA

NCBI chr 5:62,866,022...62,892,444
Ensembl chr 5:62,866,022...62,888,859

G

methylsterol monooxygenase 1

decreases expression

Ketamine results in decreased expression of MSMO1 mRNA

NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016

G

metallothionein 1

increases expression

Ketamine results in increased expression of MT1A mRNA

NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr X:10,826,032...10,827,049

G

MTCL family member 3

decreases expression

Ketamine results in decreased expression of MTCL3 mRNA

NCBI chr 1:28,629,036...28,701,416
Ensembl chr 1:28,620,293...28,701,796

G

mitochondrial transcription termination factor 2

decreases expression

Ketamine results in decreased expression of MTERF2 mRNA

NCBI chr 7:18,598,202...18,608,278
Ensembl chr 7:18,598,103...18,620,684

G

mitochondrial ribosome-associated GTPase 2

decreases expression

Ketamine results in decreased expression of MTG2 mRNA

NCBI chr 3:167,165,542...167,181,358
Ensembl chr 3:167,165,982...167,181,358

G

MYC proto-oncogene, bHLH transcription factor

decreases expression

Ketamine results in decreased expression of MYC mRNA

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

G

MYCN proto-oncogene, bHLH transcription factor

decreases expression

Ketamine results in decreased expression of MYCN mRNA

NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590

G

myosin XIX

decreases expression

Ketamine results in decreased expression of MYO19 mRNA

NCBI chr10:69,753,082...69,782,450
Ensembl chr10:69,753,068...69,782,450

G

N(alpha)-acetyltransferase 35, NatC auxiliary subunit

decreases expression

Ketamine results in decreased expression of NAA35 mRNA

NCBI chr17:5,034,360...5,086,456
Ensembl chr17:5,034,356...5,086,386

G

Ngfi-A binding protein 1

decreases expression

Ketamine results in decreased expression of NAB1 mRNA

NCBI chr 9:49,053,579...49,093,078
Ensembl chr 9:49,053,758...49,092,098

G

nucleic acid binding protein 1

decreases expression

Ketamine results in decreased expression of NABP1 mRNA

NCBI chr 9:50,098,552...50,133,982
Ensembl chr 9:50,126,726...50,134,107

G

neuron navigator 3

decreases expression

Ketamine results in decreased expression of NAV3 mRNA

NCBI chr 7:45,052,206...45,840,471
Ensembl chr 7:45,054,296...45,840,698

G

neurochondrin

increases expression

Ketamine results in increased expression of NCDN mRNA

NCBI chr 5:139,037,807...139,047,645
Ensembl chr 5:139,037,819...139,047,568

G

NCK associated protein 1 like

decreases expression
multiple interactions

Ketamine results in decreased expression of NCKAP1L mRNA
Cannabidiol inhibits the reaction [Ketamine results in decreased expression of NCKAP1L mRNA]

NCBI chr 7:134,577,470...134,622,928
Ensembl chr 7:134,577,482...134,622,934

G

NDRG family member 2

increases expression

Ketamine results in increased expression of NDRG2 mRNA

NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626

G

NADH:ubiquinone oxidoreductase core subunit S1

decreases expression

Ketamine results in decreased expression of NDUFS1 protein

NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893

G

nectin cell adhesion molecule 3

decreases expression

Ketamine results in decreased expression of NECTIN3 mRNA

NCBI chr11:54,362,712...54,469,351
Ensembl chr11:54,364,487...54,462,519

G

neurofilament heavy chain

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of NEFH mRNA

NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351

G

neurofilament light chain

decreases expression
increases expression

Ketamine results in decreased expression of NEFL protein
Ketamine results in increased expression of NEFL mRNA

PMID:18504422 PMID:20080153

NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793

G

nestin

decreases expression

Ketamine results in decreased expression of NES mRNA

NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777

G

neuronal differentiation 1

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of NEUROD1 mRNA

NCBI chr 3:64,359,554...64,363,526
Ensembl chr 3:64,359,395...64,363,649

G

neuronal differentiation 6

decreases expression

Ketamine results in decreased expression of NEUROD6 mRNA

NCBI chr 4:84,846,659...84,849,905
Ensembl chr 4:84,846,231...84,849,999

G

NFE2 like bZIP transcription factor 2

decreases expression
multiple interactions

Ketamine results in decreased expression of NFE2L2 mRNA; Ketamine results in decreased expression of NFE2L2 protein; Ketamine results in decreased expression of NFE2L2 protein modified form
Curcumin inhibits the reaction [Ketamine results in decreased expression of NFE2L2 mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of NFE2L2 protein modified form]; Curcumin inhibits the reaction [Ketamine results in decreased expression of NFE2L2 protein]

NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737

G

NFE2 like bZIP transcription factor 3

decreases expression

Ketamine results in decreased expression of NFE2L3 mRNA

NCBI chr 4:80,506,756...80,534,629
Ensembl chr 4:80,506,756...80,534,629

G

nuclear factor, interleukin 3 regulated

decreases expression

Ketamine results in decreased expression of NFIL3 mRNA

NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858

G

NFKB inhibitor alpha

increases expression
multiple interactions
increases phosphorylation

Ketamine results in increased expression of NFKBIA mRNA
TRPV4 protein affects the reaction [Ketamine results in increased phosphorylation of NFKBIA protein]

PMID:20080153 PMID:33536391

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

nerve growth factor

multiple interactions

Ketamine inhibits the reaction [Pilocarpine results in increased expression of NGF mRNA]

NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452

G

NGG1 interacting factor 3 like 1

decreases expression

Ketamine results in decreased expression of NIF3L1 mRNA

NCBI chr 9:59,980,101...60,001,490
Ensembl chr 9:59,979,799...60,000,131

G

NFKB inhibitor interacting Ras-like 1

increases expression

Ketamine results in increased expression of NKIRAS1 mRNA

NCBI chr15:7,493,531...7,503,758
Ensembl chr15:7,493,531...7,503,854

G

NK6 homeobox 2

increases expression

Ketamine results in increased expression of NKX6-2 mRNA

NCBI chr 1:194,380,149...194,383,533
Ensembl chr 1:194,381,975...194,383,515

G

neurolysin

decreases expression

Ketamine results in decreased expression of NLN mRNA

NCBI chr 2:35,133,634...35,232,927
Ensembl chr 2:35,134,145...35,232,914

G

neuromedin B

increases expression

Ketamine results in increased expression of NMB mRNA

NCBI chr 1:134,869,446...134,875,507
Ensembl chr 1:134,869,446...134,872,190

G

NME/NM23 nucleoside diphosphate kinase 6

decreases expression

Ketamine results in decreased expression of NME6 mRNA

NCBI chr 8:109,832,085...109,839,301
Ensembl chr 8:109,832,589...109,839,301

G

nicotinamide nucleotide transhydrogenase

decreases expression

Ketamine results in decreased expression of NNT mRNA

NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823

G

nucleolar protein 4

decreases expression

Ketamine results in decreased expression of NOL4 mRNA

NCBI chr18:13,932,499...14,294,873
Ensembl chr18:13,932,510...14,296,286

G

NOVA alternative splicing regulator 2

decreases expression

Ketamine results in decreased expression of NOVA2 mRNA

NCBI chr 1:78,572,253...78,613,703
Ensembl chr 1:78,572,279...78,608,021

G

nucleophosmin/nucleoplasmin, 3

decreases expression

Ketamine results in decreased expression of NPM3 mRNA

NCBI chr 1:244,595,638...244,597,623
Ensembl chr 1:244,595,644...244,597,591

G

natriuretic peptide C

decreases expression

Ketamine results in decreased expression of NPPC mRNA

NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251

G

neuropeptide Y

increases response to substance

NPY protein results in increased susceptibility to Ketamine

NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495

G

neuropeptide Y receptor Y1

decreases expression

Ketamine results in decreased expression of NPY1R mRNA

NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759

G

NAD(P)H quinone dehydrogenase 1

decreases expression
multiple interactions

Ketamine results in decreased expression of NQO1 mRNA; Ketamine results in decreased expression of NQO1 protein
Curcumin inhibits the reaction [Ketamine results in decreased expression of NQO1 mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of NQO1 protein]

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

nuclear receptor subfamily 1, group D, member 1

increases expression

Ketamine results in increased expression of NR1D1 mRNA

NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705

G

nuclear receptor subfamily 4, group A, member 2

decreases expression

Ketamine results in decreased expression of NR4A2 mRNA

NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877

G

nuclear receptor subfamily 4, group A, member 3

decreases expression

Ketamine results in decreased expression of NR4A3 mRNA

NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733

G

neurotrophin receptor associated death domain

decreases expression

Ketamine results in decreased expression of NRADD mRNA

NCBI chr 8:110,599,667...110,603,068
Ensembl chr 8:110,599,667...110,603,149

G

NRDE-2, necessary for RNA interference, domain containing

increases expression

Ketamine results in increased expression of NRDE2 mRNA

NCBI chr 6:119,405,103...119,446,861
Ensembl chr 6:119,404,334...119,448,915

G

neuronal regeneration related protein

decreases expression
multiple interactions

Ketamine results in decreased expression of NREP mRNA
[ampullosporin co-treated with Ketamine] results in increased expression of NREP mRNA

PMID:16635253 PMID:20080153

NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591

G

neuregulin 1

decreases expression

Ketamine results in decreased expression of NRG1 mRNA

NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884

G

neurogranin

increases expression

Ketamine results in increased expression of NRGN mRNA

NCBI chr 8:37,255,462...37,263,659
Ensembl chr 8:37,256,930...37,257,516

G

nuclear receptor interacting protein 3

decreases expression

Ketamine results in decreased expression of NRIP3 mRNA

NCBI chr 1:163,789,738...163,815,036
Ensembl chr 1:163,789,738...163,815,600

G

N-ethylmaleimide sensitive factor, vesicle fusing ATPase

increases expression

Ketamine results in increased expression of NSF mRNA

NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386

G

NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase

decreases expression

Ketamine results in decreased expression of NSMCE2 mRNA

NCBI chr 7:90,936,112...91,173,435
Ensembl chr 7:90,936,112...91,164,899

G

NMDA receptor synaptonuclear signaling and neuronal migration factor

multiple interactions

[ampullosporin co-treated with Ketamine] results in decreased expression of NSMF mRNA

NCBI chr 3:7,861,846...7,870,615
Ensembl chr 3:7,861,872...7,870,614

G

5'-nucleotidase, cytosolic II

increases expression

Ketamine results in increased expression of NT5C2 mRNA

NCBI chr 1:245,770,993...245,896,925
Ensembl chr 1:245,772,277...245,897,913

G

neurotrophin 3

decreases expression

Ketamine results in decreased expression of NTF3 mRNA

NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596

G

neurotrophic receptor tyrosine kinase 1

increases expression

Ketamine results in increased expression of NTRK1 mRNA

NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770

G

neurotrophic receptor tyrosine kinase 2

multiple interactions

Ketamine inhibits the reaction [Pilocarpine results in increased expression of NTRK2 mRNA]
Ketamine inhibits the reaction [NTRK2 protein binds to AP2M1 protein]

PMID:8635431 PMID:31631060

NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136

G

nudix hydrolase 6

increases expression

Ketamine results in increased expression of NUDT6 mRNA

NCBI chr 2:120,289,908...120,306,197
Ensembl chr 2:120,290,847...120,306,230

G

nucleoporin 205

decreases expression

Ketamine results in decreased expression of NUP205 mRNA

NCBI chr 4:63,854,934...63,920,852
Ensembl chr 4:63,854,783...63,920,844

G

nucleoporin 35

decreases expression

Ketamine results in decreased expression of NUP35 mRNA

NCBI chr 3:65,555,203...65,594,488
Ensembl chr 3:65,558,968...65,585,130

G

nucleoporin 42

increases expression

Ketamine results in increased expression of NUP42 mRNA

NCBI chr 4:10,985,554...11,002,591
Ensembl chr 4:10,985,554...11,002,591

G

nucleoporin 58

decreases expression

Ketamine results in decreased expression of NUP58 mRNA

NCBI chr15:34,358,170...34,407,160
Ensembl chr15:34,358,277...34,407,060

G

nucleolar and spindle associated protein 1

decreases expression

Ketamine results in decreased expression of NUSAP1 mRNA

NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624

G

occludin

multiple interactions

Ketamine inhibits the reaction [KNG1 protein results in increased expression of OCLN protein]

NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150

G

5-oxoprolinase (ATP-hydrolysing)

increases expression

Ketamine results in increased expression of OPLAH mRNA

NCBI chr 7:108,011,472...108,051,751
Ensembl chr 7:108,011,475...108,035,297

G

origin recognition complex, subunit 4

increases expression

Ketamine results in increased expression of ORC4 mRNA

NCBI chr 3:33,290,844...33,334,022
Ensembl chr 3:33,294,355...33,333,824

G

ORMDL sphingolipid biosynthesis regulator 3

increases expression

Ketamine results in increased expression of ORMDL3 mRNA

NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620

G

oxidative stress responsive kinase 1

decreases expression

Ketamine results in decreased expression of OXSR1 mRNA

NCBI chr 8:118,972,754...119,062,102
Ensembl chr 8:118,972,754...119,062,027

G

purinergic receptor P2X 6

increases expression

Ketamine results in increased expression of P2RX6 mRNA

NCBI chr11:83,439,922...83,450,449
Ensembl chr11:83,439,924...83,450,481

G

prolyl 4-hydroxylase subunit alpha 1

decreases expression

Ketamine results in decreased expression of P4HA1 mRNA

NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786

G

prolyl 4-hydroxylase, transmembrane

increases expression

Ketamine results in increased expression of P4HTM mRNA

NCBI chr 8:109,274,629...109,292,802
Ensembl chr 8:109,274,626...109,292,473

G

p21 (RAC1) activated kinase 5

decreases expression

Ketamine results in decreased expression of PAK5 mRNA

NCBI chr 3:123,395,678...123,703,967
Ensembl chr 3:123,396,497...123,703,930

G

pantothenate kinase 1

decreases expression

Ketamine results in decreased expression of PANK1 mRNA

NCBI chr 1:232,324,718...232,395,445
Ensembl chr 1:232,328,430...232,396,829

G

poly (A) polymerase alpha

decreases expression

Ketamine results in decreased expression of PAPOLA mRNA

NCBI chr 6:124,682,015...124,734,706
Ensembl chr 6:124,682,105...124,734,468

G

par-6 family cell polarity regulator gamma

decreases expression

Ketamine results in decreased expression of PARD6G mRNA

NCBI chr18:73,497,992...73,565,048
Ensembl chr18:73,498,021...73,565,029

G

PATJ, crumbs cell polarity complex component

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of PATJ mRNA

NCBI chr 5:113,061,985...113,364,807
Ensembl chr 5:113,062,118...113,364,807

G

PDZ binding kinase

decreases expression

Ketamine results in decreased expression of PBK mRNA

NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014

G

PBX homeobox 3

decreases expression

Ketamine results in decreased expression of PBX3 mRNA

NCBI chr 3:17,488,691...17,682,412
Ensembl chr 3:17,488,693...17,682,791

G

polycomb group ring finger 6

decreases expression

Ketamine results in decreased expression of PCGF6 mRNA

NCBI chr 1:245,925,354...245,944,964
Ensembl chr 1:245,925,360...245,944,914

G

PCNA clamp associated factor

decreases expression

Ketamine results in decreased expression of PCLAF mRNA

NCBI chr 8:66,420,606...66,432,994
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994

G

proprotein convertase subtilisin/kexin type 2

increases expression

Ketamine results in increased expression of PCSK2 mRNA

NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127

G

proprotein convertase subtilisin/kexin type 6

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of PCSK6 mRNA

NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:119,429,265...119,627,596

G

phosphodiesterase 12

increases expression

Ketamine results in increased expression of PDE12 mRNA

NCBI chr16:1,920,062...1,925,638
Ensembl chr16:1,915,386...1,925,887

G

phosphodiesterase 2A

multiple interactions

[ampullosporin co-treated with Ketamine] results in decreased expression of PDE2A mRNA

NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434

G

protein disulfide isomerase family A, member 2

decreases expression

Ketamine results in decreased expression of PDIA2 mRNA

NCBI chr10:15,215,824...15,218,937
Ensembl chr10:15,215,824...15,220,931

G

protein disulfide isomerase family A, member 4

decreases expression

Ketamine results in decreased expression of PDIA4 mRNA

NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107

G

protein disulfide isomerase family A, member 5

decreases expression

Ketamine results in decreased expression of PDIA5 mRNA

NCBI chr11:65,272,152...65,359,087
Ensembl chr11:65,272,155...65,359,084

G

protein disulfide isomerase family A, member 6

decreases expression

Ketamine results in decreased expression of PDIA6 mRNA

NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613

G

PDLIM1 interacting kinase 1 like

decreases expression

Ketamine results in decreased expression of PDIK1L mRNA

NCBI chr 5:146,495,115...146,507,363
Ensembl chr 5:146,495,115...146,506,835

G

pyruvate dehydrogenase kinase 2

increases expression

Ketamine results in increased expression of PDK2 mRNA

NCBI chr10:79,972,550...79,987,074
Ensembl chr10:79,972,556...79,987,085

G

PDZ and LIM domain 7

decreases expression

Ketamine results in decreased expression of PDLIM7 mRNA

NCBI chr17:9,124,565...9,139,814
Ensembl chr17:9,124,649...9,139,811

G

pyruvate dehydrogenase phosphatase catalytic subunit 2

decreases expression

Ketamine results in decreased expression of PDP2 mRNA

NCBI chr19:386,408...394,068
Ensembl chr19:386,406...394,074

G

p53 and DNA damage regulated 1

increases expression

Ketamine results in increased expression of PDRG1 mRNA

NCBI chr 3:141,477,561...141,483,730
Ensembl chr 3:141,476,501...141,483,858
Ensembl chr 3:141,476,501...141,483,858

G

penta-EF hand domain containing 1

increases expression

Ketamine results in increased expression of PEF1 mRNA

NCBI chr 5:142,451,791...142,475,061
Ensembl chr 5:142,451,778...142,475,067

G

period circadian regulator 1

increases expression

Ketamine results in increased expression of PER1 mRNA

NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431

G

period circadian regulator 2

multiple interactions

[ampullosporin co-treated with Ketamine] results in decreased expression of PER2 mRNA

NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459

G

peroxisomal biogenesis factor 6

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of PEX6 mRNA

NCBI chr 9:14,258,145...14,270,335
Ensembl chr 9:14,258,145...14,270,303

G

pyroglutamyl-peptidase I

decreases expression

Ketamine results in decreased expression of PGPEP1 mRNA

NCBI chr16:18,770,563...18,782,968
Ensembl chr16:18,771,021...18,783,478

G

phosphatase and actin regulator 3

decreases expression

Ketamine results in decreased expression of PHACTR3 mRNA

NCBI chr 3:165,205,247...165,423,692
Ensembl chr 3:165,205,255...165,423,153

G

prohibitin 1

increases expression

Ketamine results in increased expression of PHB1 protein

NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042

G

PHD finger protein 13

decreases expression

Ketamine results in decreased expression of PHF13 mRNA

NCBI chr 5:162,494,574...162,501,350
Ensembl chr 5:162,494,573...162,501,350

G

PHD finger protein 14

decreases expression

Ketamine results in decreased expression of PHF14 mRNA

NCBI chr 4:40,009,691...40,195,877
Ensembl chr 4:40,009,264...40,195,885

G

PHD and ring finger domains 1

decreases expression

Ketamine results in decreased expression of PHRF1 mRNA

NCBI chr 1:196,333,663...196,366,901
Ensembl chr 1:196,333,903...196,366,892

G

phytanoyl-CoA 2-hydroxylase interacting protein

increases expression

Ketamine results in increased expression of PHYHIP mRNA

NCBI chr15:45,533,974...45,545,223
Ensembl chr15:45,533,974...45,545,221

G

progesterone immunomodulatory binding factor 1

decreases expression

Ketamine results in decreased expression of PIBF1 mRNA

NCBI chr15:75,850,389...76,019,711
Ensembl chr15:75,850,624...76,019,712

G

phosphatidylinositol glycan anchor biosynthesis, class L

decreases expression

Ketamine results in decreased expression of PIGL mRNA

NCBI chr10:47,142,160...47,199,892
Ensembl chr10:47,141,780...47,200,145

G

phosphoinositide-3-kinase adaptor protein 1

decreases expression

Ketamine results in decreased expression of PIK3AP1 mRNA

NCBI chr 1:240,090,854...240,245,007
Ensembl chr 1:240,093,065...240,204,828

G

phosphoinositide-3-kinase interacting protein 1

increases expression

Ketamine results in increased expression of PIK3IP1 mRNA

NCBI chr14:78,204,668...78,216,616
Ensembl chr14:78,204,053...78,216,608

G

phosphatidylinositol-5-phosphate 4-kinase type 2 alpha

decreases expression

Ketamine results in decreased expression of PIP4K2A mRNA

NCBI chr17:81,496,669...81,668,180
Ensembl chr17:81,496,670...81,668,029

G

polycystin 1, transient receptor potential channel interacting

increases expression

Ketamine results in increased expression of PKD1 mRNA

NCBI chr10:13,573,779...13,621,138
Ensembl chr10:13,573,021...13,621,128

G

phospholipase A and acyltransferase 3

increases expression

Ketamine results in increased expression of PLAAT3 mRNA

NCBI chr 1:204,782,608...204,816,397
Ensembl chr 1:204,782,729...204,817,667

G

plasminogen activator, tissue type

increases expression

Ketamine results in increased expression of PLAT mRNA

NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223

G

phospholipase C, delta 4

increases expression

Ketamine results in increased expression of PLCD4 mRNA

NCBI chr 9:76,115,523...76,158,602
Ensembl chr 9:76,117,168...76,142,453

G

phospholipase C-like 1

decreases expression

Ketamine results in decreased expression of PLCL1 mRNA

NCBI chr 9:56,901,573...57,238,782
Ensembl chr 9:56,901,534...57,238,782

G

phosphatidylinositol-specific phospholipase C, X domain containing 3

decreases expression

Ketamine results in decreased expression of PLCXD3 mRNA

NCBI chr 2:53,567,022...53,746,384
Ensembl chr 2:53,567,022...53,746,384

G

phospholipase D family, member 4

increases expression

Ketamine results in increased expression of PLD4 mRNA

NCBI chr 6:131,818,860...131,827,457
Ensembl chr 6:131,818,860...131,826,376

G

pleckstrin homology domain containing B1

increases expression

Ketamine results in increased expression of PLEKHB1 mRNA

NCBI chr 1:154,998,798...155,013,094
Ensembl chr 1:154,998,800...155,016,142

G

pleckstrin homology and FYVE domain containing 2

decreases expression

Ketamine results in decreased expression of PLEKHF2 mRNA

NCBI chr 5:24,091,077...24,106,758
Ensembl chr 5:24,090,688...24,106,601

G

plasminogen receptor with a C-terminal lysine

decreases expression

Ketamine results in decreased expression of PLGRKT mRNA

NCBI chr 1:227,099,005...227,111,277
Ensembl chr 1:227,099,015...227,111,194

G

proteolipid protein 1

increases expression

Ketamine results in increased expression of PLP1 mRNA

NCBI chr X:100,184,039...100,201,035
Ensembl chr X:100,185,767...100,201,032

G

phospholipid phosphatase related 1

decreases expression

Ketamine results in decreased expression of PLPPR1 mRNA

NCBI chr 5:63,437,457...63,725,286
Ensembl chr 5:63,437,816...63,763,835

G

plasmalemma vesicle associated protein

increases expression

Ketamine results in increased expression of PLVAP mRNA

NCBI chr16:18,184,985...18,197,301
Ensembl chr16:18,184,975...18,197,301

G

plexin A2

decreases expression

Ketamine results in decreased expression of PLXNA2 mRNA

NCBI chr13:106,163,103...106,358,979
Ensembl chr13:106,163,103...106,358,979

G

peptidase, mitochondrial processing subunit alpha

increases expression

Ketamine results in increased expression of PMPCA mRNA

NCBI chr 3:9,207,731...9,216,846
Ensembl chr 3:9,207,717...9,216,844

G

purine nucleoside phosphorylase

decreases expression

Ketamine results in decreased expression of PNP mRNA

NCBI chr15:24,170,607...24,178,269
Ensembl chr15:24,170,602...24,203,986

G

patatin-like phospholipase domain containing 2

increases expression

Ketamine results in increased expression of PNPLA2 mRNA

NCBI chr 1:196,552,723...196,557,805
Ensembl chr 1:196,552,723...196,557,805

G

protein O-fucosyltransferase 2

decreases expression

Ketamine results in decreased expression of POFUT2 mRNA

NCBI chr20:11,367,073...11,377,788
Ensembl chr20:11,367,096...11,377,743

G

DNA polymerase alpha 1, catalytic subunit

decreases expression

Ketamine results in decreased expression of POLA1 mRNA

NCBI chr X:58,034,617...58,348,612
Ensembl chr X:58,034,619...58,348,536

G

DNA polymerase delta 1, catalytic subunit

decreases expression

Ketamine results in decreased expression of POLD1 mRNA

NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465

G

DNA polymerase epsilon 2, accessory subunit

decreases expression

Ketamine results in decreased expression of POLE2 mRNA

NCBI chr 6:87,674,702...87,712,723
Ensembl chr 6:87,674,702...87,699,305

G

DNA polymerase gamma, catalytic subunit

decreases expression

Ketamine results in decreased expression of POLG mRNA

NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567

G

RNA polymerase II, I and III subunit F

increases expression

Ketamine results in increased expression of POLR2F mRNA

NCBI chr 7:110,712,528...110,724,234
Ensembl chr 7:110,712,572...110,724,234

G

RNA polymerase III subunit F

increases expression

Ketamine results in increased expression of POLR3F mRNA

NCBI chr 3:131,908,466...131,924,838
Ensembl chr 3:131,908,466...131,924,837

G

RNA polymerase III subunit H

decreases expression

Ketamine results in decreased expression of POLR3H mRNA

NCBI chr 7:113,429,434...113,439,743
Ensembl chr 7:113,429,451...113,439,778

G

protein-O-mannosyltransferase 2

decreases expression

Ketamine results in decreased expression of POMT2 mRNA

NCBI chr 6:106,755,462...106,794,849
Ensembl chr 6:106,755,462...106,794,849

G

POTE ankyrin domain family member M

increases expression

Ketamine results in increased expression of POTEM mRNA

NCBI chr16:20,193,646...20,311,924
Ensembl chr16:19,949,230...19,976,541

G

POU class 3 homeobox 2

decreases expression

Ketamine results in decreased expression of POU3F2 mRNA

NCBI chr 5:36,077,930...36,083,838
Ensembl chr 5:36,077,930...36,083,838

G

protein phosphatase, Mg2+/Mn2+ dependent, 1D

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of PPM1D mRNA

NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607

G

protein phosphatase 1, regulatory (inhibitor) subunit 14B

decreases expression

Ketamine results in decreased expression of PPP1R14B mRNA

NCBI chr 1:204,165,210...204,167,320
Ensembl chr 1:204,163,299...204,167,319
Ensembl chr12:204,163,299...204,167,319

G

protein phosphatase 1, regulatory subunit 18

decreases expression

Ketamine results in decreased expression of PPP1R18 mRNA

NCBI chr20:2,877,567...2,887,526
Ensembl chr20:2,877,567...2,891,802

G

protein phosphatase 1, regulatory (inhibitor) subunit 1B

increases expression

Ketamine results in increased expression of PPP1R1B mRNA

NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775

G

PPARG related coactivator 1

decreases expression

Ketamine results in decreased expression of PPRC1 mRNA

NCBI chr 1:244,901,985...244,918,587
Ensembl chr 1:244,902,179...244,918,587

G

protein kinase AMP-activated non-catalytic subunit gamma 2

decreases expression

Ketamine results in decreased expression of PRKAG2 mRNA

NCBI chr 4:10,010,890...10,252,155
Ensembl chr 4:10,010,890...10,252,142

G

protein kinase C, gamma

increases expression

Ketamine results in increased expression of PRKCG mRNA

NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384

G

prolactin

decreases expression

Ketamine results in decreased expression of PRL protein

NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062

G

protein arginine methyltransferase 2

decreases expression

Ketamine results in decreased expression of PRMT2 mRNA

NCBI chr20:12,394,748...12,420,643
Ensembl chr20:12,394,798...12,420,643

G

pre-mRNA processing factor 38B

decreases expression

Ketamine results in decreased expression of PRPF38B mRNA

NCBI chr 2:196,553,224...196,562,271
Ensembl chr 2:196,553,225...196,562,250

G

pre-mRNA processing factor 4B

decreases expression

Ketamine results in decreased expression of PRPF4B mRNA

NCBI chr17:29,985,343...30,020,285
Ensembl chr17:29,985,343...30,019,625

G

proline rich 16

decreases expression

Ketamine results in decreased expression of PRR16 mRNA

NCBI chr18:44,424,348...44,764,796
Ensembl chr18:44,424,616...44,632,329

G

prosaposin

increases expression

Ketamine results in increased expression of PSAP mRNA

NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498

G

patched domain containing 1

decreases expression

Ketamine results in decreased expression of PTCHD1 mRNA

NCBI chr X:39,681,910...39,733,416
Ensembl chr X:39,681,910...39,733,519

G

prostaglandin D2 synthase

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of PTGDS mRNA

NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833

G

prostaglandin F2 receptor inhibitor

multiple interactions

[ampullosporin co-treated with Ketamine] results in decreased expression of PTGFRN mRNA

NCBI chr 2:188,469,521...188,544,795
Ensembl chr 2:188,469,521...188,544,795

G

protein tyrosine kinase 2

decreases expression

Ketamine results in decreased expression of PTK2 mRNA

NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783

G

protein tyrosine kinase 2 beta

multiple interactions

[ampullosporin co-treated with Ketamine] results in decreased expression of PTK2B mRNA

NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282

G

protein tyrosine phosphatase, non-receptor type 5

multiple interactions

[ampullosporin co-treated with Ketamine] results in decreased expression of PTPN5 mRNA

NCBI chr 1:97,620,638...97,681,186
Ensembl chr 1:97,620,642...97,679,882

G

protein tyrosine phosphatase, receptor type, H

decreases expression

Ketamine results in decreased expression of PTPRH mRNA

NCBI chr 1:69,243,704...69,276,294
Ensembl chr 1:69,242,321...69,285,077

G

protein tyrosine phosphatase, receptor type, N

increases expression

Ketamine results in increased expression of PTPRN mRNA

NCBI chr 9:76,741,010...76,756,704
Ensembl chr 9:76,741,016...76,756,190

G

protein tyrosine phosphatase, receptor type, R

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of PTPRR mRNA

NCBI chr 7:51,662,595...51,929,605
Ensembl chr 7:51,662,595...51,929,603

G

protein tyrosine phosphatase, receptor type, U

increases expression

Ketamine results in increased expression of PTPRU mRNA

NCBI chr 5:143,950,542...144,024,791
Ensembl chr 5:143,950,965...144,024,768

G

parvalbumin

multiple interactions
decreases expression

acetovanillone inhibits the reaction [Ketamine results in decreased expression of PVALB protein]
[ampullosporin co-treated with Ketamine] results in increased expression of PVALB mRNA

PMID:16635253 PMID:18063801

NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561

G

PWWP domain containing 3A, DNA repair factor

decreases expression

Ketamine results in decreased expression of PWWP3A mRNA

NCBI chr 7:9,465,180...9,482,053
Ensembl chr 7:9,465,195...9,481,966

G

glycogen phosphorylase, muscle associated

increases expression

Ketamine results in increased expression of PYGM mRNA

NCBI chr 1:203,690,550...203,705,369
Ensembl chr 1:203,690,533...203,705,368

G

RAB26, member RAS oncogene family

increases expression

Ketamine results in increased expression of RAB26 mRNA

NCBI chr10:13,553,395...13,558,063
Ensembl chr10:13,553,395...13,558,030

G

receptor activity modifying protein 1

increases expression

Ketamine results in increased expression of RAMP1 mRNA

NCBI chr 9:91,765,481...91,816,152
Ensembl chr 9:91,781,285...91,816,151

G

RAS p21 protein activator 1

decreases expression

Ketamine results in decreased expression of RASA1 mRNA

NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854

G

RASD family, member 2

increases expression

Ketamine results in increased expression of RASD2 mRNA

NCBI chr19:13,594,291...13,605,016
Ensembl chr19:13,594,291...13,605,016

G

RAS protein-specific guanine nucleotide-releasing factor 1

increases expression

Ketamine results in increased expression of RASGRF1 mRNA

NCBI chr 8:90,445,154...90,574,274
Ensembl chr 8:90,445,154...90,574,269

G

RAS-like family 11 member A

increases expression

Ketamine results in increased expression of RASL11A mRNA

NCBI chr12:8,258,148...8,260,909
Ensembl chr12:8,258,159...8,262,576

G

RAS-like family 11 member B

increases expression

Ketamine results in increased expression of RASL11B mRNA

NCBI chr14:34,014,924...34,019,146
Ensembl chr14:34,014,509...34,019,152

G

Ras association domain family member 2

decreases expression

Ketamine results in decreased expression of RASSF2 mRNA

NCBI chr 3:119,244,288...119,280,462
Ensembl chr 3:119,245,821...119,280,431

G

Ras association domain family member 5

increases expression

Ketamine results in increased expression of RASSF5 mRNA

NCBI chr13:42,637,513...42,703,024
Ensembl chr13:42,637,549...42,703,024

G

RB transcriptional corepressor 1

decreases expression

Ketamine results in decreased expression of RB1 mRNA

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

RB binding protein 6, ubiquitin ligase

increases expression

Ketamine results in increased expression of RBBP6 mRNA

NCBI chr 1:177,503,988...177,537,397
Ensembl chr 1:177,503,313...177,535,678

G

RB binding protein 8, endonuclease

decreases expression

Ketamine results in decreased expression of RBBP8 mRNA

NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846

G

RNA binding motif protein 12B

decreases expression

Ketamine results in decreased expression of RBM12B mRNA

NCBI chr 5:25,597,405...25,610,324
Ensembl chr 5:25,590,493...25,611,245

G

RNA binding motif protein 4

decreases expression

Ketamine results in decreased expression of RBM4 mRNA

NCBI chr 1:202,078,442...202,087,506
Ensembl chr 1:202,085,279...202,105,380

G

RNA binding motif protein 4B

decreases expression

Ketamine results in decreased expression of RBM4B mRNA

NCBI chr 1:202,047,934...202,058,025
Ensembl chr 1:202,047,927...202,058,020

G

RNA binding motif, single stranded interacting protein 1

decreases expression

Ketamine results in decreased expression of RBMS1 mRNA

NCBI chr 3:45,195,828...45,420,406
Ensembl chr 3:45,197,972...45,420,376

G

retinol binding protein 4

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of RBP mRNA

NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399

G

RecQ like helicase

decreases expression

Ketamine results in decreased expression of RECQL mRNA

NCBI chr 4:175,308,337...175,332,965
Ensembl chr 4:175,304,117...175,332,945

G

receptor accessory protein 5

decreases expression

Ketamine results in decreased expression of REEP5 mRNA

NCBI chr18:25,945,375...25,983,271
Ensembl chr18:25,945,381...25,976,509

G

RELA proto-oncogene, NF-kB subunit

increases phosphorylation
multiple interactions

Ketamine results in increased phosphorylation of RELA protein
TRPV4 protein affects the reaction [Ketamine results in increased phosphorylation of RELA protein]

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

RRAD and GEM like GTPase 2

decreases expression

Ketamine results in decreased expression of REM2 mRNA

NCBI chr15:27,933,950...27,938,429
Ensembl chr15:27,933,950...27,938,429

G

renin

increases expression

Ketamine results in increased expression of REN protein

NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489

G

regulated endocrine-specific protein 18

increases expression

Ketamine results in increased expression of RESP18 mRNA

NCBI chr 9:76,765,179...76,771,824
Ensembl chr 9:76,764,590...76,778,722

G

REV1, DNA directed polymerase

increases expression

Ketamine results in increased expression of REV1 mRNA

NCBI chr 9:40,278,100...40,351,764
Ensembl chr 9:40,278,101...40,351,576

G

regulator of G-protein signaling 12

multiple interactions

[ampullosporin co-treated with Ketamine] results in decreased expression of RGS12 mRNA

NCBI chr14:75,715,925...75,824,012
Ensembl chr14:75,715,934...75,794,596

G

regulator of G-protein signaling 19

decreases expression

Ketamine results in decreased expression of RGS19 mRNA

NCBI chr 3:168,804,532...168,813,035
Ensembl chr 3:168,804,874...168,810,097

G

regulator of G-protein signaling 2

decreases expression

Ketamine results in decreased expression of RGS2 mRNA

NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385

G

regulator of G-protein signaling 3

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of RGS3 mRNA

NCBI chr 5:76,022,038...76,161,895
Ensembl chr 5:76,022,001...76,161,894

G

regulator of G-protein signaling 4

multiple interactions

[ampullosporin co-treated with Ketamine] results in decreased expression of RGS4 mRNA

NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068

G

regulator of G-protein signaling 9

increases expression

Ketamine results in increased expression of RGS9 mRNA

NCBI chr10:94,195,265...94,270,892
Ensembl chr10:94,197,054...94,270,892

G

ribonuclease A family member 4

increases expression

Ketamine results in increased expression of RNASE4 mRNA

NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117

G

Rho family GTPase 3

decreases expression

Ketamine results in decreased expression of RND3 mRNA

NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327

G

ring finger protein 112

increases expression

Ketamine results in increased expression of RNF112 mRNA

NCBI chr10:46,121,146...46,126,691
Ensembl chr10:46,121,148...46,126,699

G

ring finger protein 138

decreases expression

Ketamine results in decreased expression of RNF138 mRNA

NCBI chr18:12,291,557...12,315,931
Ensembl chr18:12,291,590...12,315,930

G

ring finger protein 31

increases expression

Ketamine results in increased expression of RNF31 mRNA

NCBI chr15:29,083,047...29,095,328
Ensembl chr15:29,083,631...29,101,915

G

renalase, FAD-dependent amine oxidase

increases expression

Ketamine results in increased expression of RNLS mRNA

NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823

G

RAR-related orphan receptor A

increases expression

Ketamine results in increased expression of RORA mRNA

NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931

G

ribosome production factor 2 homolog

decreases expression

Ketamine results in decreased expression of RPF2 mRNA

NCBI chr20:43,630,003...43,651,477
Ensembl chr20:43,629,951...43,651,509

G

ribosomal protein L24

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of RPL24 mRNA

NCBI chr11:44,653,937...44,659,346
Ensembl chr11:44,653,937...44,659,370

G

ribosomal protein S6 kinase A1

multiple interactions

[ampullosporin co-treated with Ketamine] results in increased expression of RPS6KA1 mRNA

NCBI chr 5:146,079,018...146,118,272
Ensembl chr 5:146,079,021...146,118,272

G

RNA pseudouridine synthase D3

increases expression

Ketamine results in increased expression of RPUSD3 mRNA

NCBI chr 4:146,553,743...146,562,789
Ensembl chr 4:146,558,562...146,562,794

G

RAS related 2

decreases expression

Ketamine results in decreased expression of RRAS2 mRNA

NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111

G

ribonucleotide reductase regulatory subunit M2

decreases expression

Ketamine results in decreased expression of RRM2 mRNA

NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773

G

ribosomal RNA processing 1B

increases expression

Ketamine results in increased expression of RRP1B mRNA

NCBI chr20:10,123,111...10,148,704
Ensembl chr20:10,123,125...10,147,928

G

ribosomal RNA processing 7 homolog A

decreases expression

Ketamine results in decreased expression of RRP7A mRNA

NCBI chr 7:114,262,929...114,272,817
Ensembl chr 7:114,256,472...114,272,817

G

RT1 class Ib, locus S3

increases expression

Ketamine results in increased expression of RT1-S3 mRNA

NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411

G

RT1 class I, locus T24, gene 4

increases expression

Ketamine results in increased expression of RT1-T24-4 mRNA

NCBI chr20:2,684,515...2,747,878
Ensembl chr20:2,684,515...2,692,511
Ensembl chr20:2,684,515...2,692,511

G

rhotekin

increases expression

Ketamine results in increased expression of RTKN mRNA

NCBI chr 4:115,640,813...115,657,952
Ensembl chr 4:115,640,774...115,657,952

G

RUN domain containing 3A

increases expression

Ketamine results in increased expression of RUNDC3A mRNA

NCBI chr10:87,352,624...87,361,767
Ensembl chr10:87,352,646...87,361,765

G

RWD domain containing 2A