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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 3.5.1.98 (histone deacetylase) inhibitor
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Accession:CHEBI:61115 term browser browse the term
Definition:An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98).
Synonyms:related_synonym: EC 3.5.1.98 inhibitor;   EC 3.5.1.98 inhibitors;   HDAC inhibitor;   HDAC inhibitors;   HDACi;   HDACis;   HDI;   HDIs;   histone amidohydrolase inhibitor;   histone amidohydrolase inhibitors;   histone deacetylase (EC 3.5.1.98) inhibitors;   histone deacetylase inhibitor;   histone deacetylase inhibitors
 xref: Wikipedia:Histone_deacetylase_inhibitor



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      CHEBI ontology 21873
        role 21858
          biological role 21856
            biochemical role 21115
              enzyme inhibitor 19420
                EC 3.* (hydrolase) inhibitor 18954
                  EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor 18678
                    EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor 18678
                      EC 3.5.1.98 (histone deacetylase) inhibitor 15448
                        3',4'-dihydroxyaurone 0
                        4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide 0
                        4-phenylbutyric acid 197
                        BML-210 0
                        BPDZ 711 0
                        CG-1521 0
                        CHIC-35 0
                        HC toxin 11
                        MC1568 10
                        Sir1 inhibitor + 0
                        Sir2 inhibitor + 183
                        belinostat 658
                        bis-(4-hydroxybenzyl)sulfide 0
                        butyrate + 94
                        caffeic acid + 574
                        carbamazepine + 2038
                        curcumin + 919
                        depudecin + 0
                        entinostat + 2525
                        methylseleninic acid 406
                        nicotinamide + 146
                        panobinostat 1301
                        panobinostat lactate 0
                        pracinostat 0
                        pyridin-3-ylmethyl \{4-[(2-amino-4-fluorophenyl)carbamoyl]benzyl\}carbamate 0
                        romidepsin 48
                        sirtinol 62
                        sodium butyrate 0
                        sodium phenylbutyrate 0
                        spiruchostatin B 3
                        sulforaphane + 1827
                        tacedinaline 17
                        trapoxin A 0
                        tributyrin 11
                        trichostatin A + 4935
                        tubastatin A 5
                        valproic acid + 14701
                        vorinostat 2607
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