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ONTOLOGY REPORT - ANNOTATIONS


Term:EC 3.5.1.98 (histone deacetylase) inhibitor
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Accession:CHEBI:61115 term browser browse the term
Definition:An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98).
Synonyms:related_synonym: EC 3.5.1.98 inhibitor;   EC 3.5.1.98 inhibitors;   HDAC inhibitor;   HDAC inhibitors;   HDACi;   HDACis;   HDI;   HDIs;   histone amidohydrolase inhibitor;   histone amidohydrolase inhibitors;   histone deacetylase (EC 3.5.1.98) inhibitors;   histone deacetylase inhibitor;   histone deacetylase inhibitors
 xref: Wikipedia:Histone_deacetylase_inhibitor


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  CHEBI ontology 19789
    role 19735
      biological role 19734
        biochemical role 19227
          enzyme inhibitor 18102
            EC 3.* (hydrolase) inhibitor 17591
              EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor 17471
                EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor 17471
                  EC 3.5.1.98 (histone deacetylase) inhibitor 14913
                    3',4'-dihydroxyaurone 0
                    4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide 0
                    4-phenylbutyric acid 171
                    BML-210 0
                    BPDZ 711 0
                    CHIC-35 0
                    HC toxin 0
                    MC1568 10
                    Sir1 inhibitor + 0
                    Sir2 inhibitor + 169
                    belinostat 647
                    bis-(4-hydroxybenzyl)sulfide 0
                    butyrate + 80
                    caffeic acid + 551
                    carbamazepine + 2028
                    curcumin + 862
                    depudecin + 0
                    entinostat + 2483
                    methylseleninic acid 404
                    nicotinamide + 135
                    panobinostat 1262
                    panobinostat lactate 0
                    pracinostat 0
                    pyridin-3-ylmethyl \{4-[(2-amino-4-fluorophenyl)carbamoyl]benzyl\}carbamate 0
                    romidepsin 41
                    sirtinol 58
                    sodium butyrate 0
                    sodium phenylbutyrate 0
                    spiruchostatin B 3
                    sulforaphane + 1778
                    tacedinaline 1
                    trapoxin A 0
                    tributyrin 11
                    tubastatin A 2
                    valproic acid + 14331
                    vorinostat 2556
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.