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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:carfentanil
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Accession:CHEBI:61084 term browser browse the term
Definition:A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of methyl 4-anilino-1-(2-phenylethyl)piperidine-4-carboxylate with propanoic acid.
Synonyms:exact_synonym: methyl 1-(2-phenylethyl)-4-[phenyl(propionyl)amino]piperidine-4-carboxylate
 related_synonym: 4-((1-Oxopropyl)phenylamino)-1-(2-phenylethyl)-4-piperidinecarboxylic acid methyl ester;   Formula=C24H30N2O3;   InChI=1S/C24H30N2O3/c1-3-22(27)26(21-12-8-5-9-13-21)24(23(28)29-2)15-18-25(19-16-24)17-14-20-10-6-4-7-11-20/h4-13H,3,14-19H2,1-2H3;   InChIKey=YDSDEBIZUNNPOB-UHFFFAOYSA-N;   Methyl 1-phenylethyl-4-(N-phenylpropionamido)isonipecotate;   Methyl 4-(N-(1-oxopropyl)-N-phenylamino)-1-(2-phenylethyl)-4-piperidinecarboxylate;   Methyl 4-(N-propionyl-N-phenylamino)-1-(2-phenylethyl)-4-piperidine-carboxylate;   SMILES=CCC(=O)N(c1ccccc1)C1(CCN(CCc2ccccc2)CC1)C(=O)OC;   Wildnil;   carfentanilo;   carfentanilum;   carfentanyl
 xref: CAS:59708-52-0;   DrugBank:DB01535;   KEGG:D07620
 xref_mesh: MESH:C017114
 xref: PMID:16621415;   PMID:1847432;   PMID:2167979;   PMID:28830120;   PMID:28851500;   PMID:29329388;   PMID:29367860;   PMID:29679387;   PMID:6288945;   Reaxys:456976;   Wikipedia:Carfentanil


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carfentanil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases metabolic processing ISO CYP2C8 protein results in increased metabolism of carfentanil CTD PMID:33652071
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing ISO CYP3A4 protein results in increased metabolism of carfentanil CTD PMID:33652071 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases metabolic processing ISO CYP3A5 protein results in increased metabolism of carfentanil CTD PMID:33652071 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions ISO Capsaicin inhibits the reaction [carfentanil binds to OPRM1 protein]; Cocaine affects the reaction [carfentanil binds to OPRM1 protein] CTD PMID:12406535 PMID:15953495 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link

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  CHEBI ontology 19821
    role 19769
      application 19481
        fuel 11017
          methanol 3861
            methyl ester 3833
              carfentanil 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic acid 18373
                                        carboacyl group 17485
                                          univalent carboacyl group 17485
                                            carbamoyl group 17299
                                              carboxamide 17299
                                                tertiary carboxamide 189
                                                  carfentanil 4
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