CHEBI ONTOLOGY - ANNOTATIONS |
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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Term: | tacrolimus (anhydrous) |
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Accession: | CHEBI:61049
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browse the term
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Definition: | A macrolide lactam containing a 23-membered lactone ring, originally isolated from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. |
Synonyms: | exact_synonym: | (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone |
| related_synonym: | 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN; FK 506; FK506; Formula=C44H69NO12; InChI=1S/C44H69NO12/c1-10-13-31-19-25(2)18-26(3)20-37(54-8)40-38(55-9)22-28(5)44(52,57-40)41(49)42(50)45-17-12-11-14-32(45)43(51)56-39(29(6)34(47)24-35(31)48)27(4)21-30-15-16-33(46)36(23-30)53-7/h10,19,21,26,28-34,36-40,46-47,52H,1,11-18,20,22-24H2,2-9H3/b25-19+,27-21+/t26-,28+,29+,30-,31+,32-,33+,34-,36+,37-,38-,39+,40+,44+/m0/s1; InChIKey=QJJXYPPXXYFBGM-LFZNUXCKSA-N; Prograf; SMILES=CO[C@@H]1C[C@@H](CC[C@H]1O)\\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@H]([C@H](C[C@@H](C)C\\C(C)=C\\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC)[C@H](C[C@H]2C)OC; Tacrolimus |
| alt_id: | CHEBI:42555; CHEBI:4958 |
| xref: | CAS:104987-11-3; DrugBank:DB00864; KEGG:C01375; KEGG:D08556; LIPID_MAPS_instance:LMPK04000003; PDBeChem:FK5; Patent:EP184162; Patent:US5665727; Reaxys:3647477; Reaxys:8821611 |
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Please select species to view GViewer data.
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Cxcr4 |
C-X-C motif chemokine receptor 4 |
decreases expression increases expression |
EXP |
tacrolimus co-treated with plerixafor decreases expression of CXCR4 protein in liver tacrolimus increases expression of CXCR4 protein in liver |
RGD |
PMID:24912495 PMID:24912495 |
RGD:151893463, RGD:151893463 |
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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Cxcr4 |
chemokine (C-X-C motif) receptor 4 |
decreases expression increases expression |
ISO |
tacrolimus co-treated with plerixafor decreases expression of CXCR4 protein in liver tacrolimus increases expression of CXCR4 protein in liver |
RGD |
PMID:24912495 PMID:24912495 |
RGD:151893463, RGD:151893463 |
NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030
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CXCR4 |
C-X-C motif chemokine receptor 4 |
decreases expression increases expression |
ISO |
tacrolimus co-treated with plerixafor decreases expression of CXCR4 protein in liver tacrolimus increases expression of CXCR4 protein in liver |
RGD |
PMID:24912495 PMID:24912495 |
RGD:151893463, RGD:151893463 |
NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177
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A2m |
alpha-2-macroglobulin |
increases expression |
EXP |
Tacrolimus results in increased expression of A2M mRNA |
CTD |
PMID:21865292 |
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NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
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A2m |
alpha-2-macroglobulin |
increases expression |
ISO |
Tacrolimus results in increased expression of A2M mRNA |
CTD |
PMID:21865292 |
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NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186
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A2M |
alpha-2-macroglobulin |
increases expression |
ISO |
Tacrolimus results in increased expression of A2M mRNA |
CTD |
PMID:21865292 |
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NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229
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Abca1 |
ATP binding cassette subfamily A member 1 |
multiple interactions increases expression |
ISO EXP |
[Sirolimus co-treated with Tacrolimus] results in increased expression of ABCA1 protein Tacrolimus results in increased expression of ABCA1 mRNA |
CTD |
PMID:17016853 PMID:21865292 |
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NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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Abca1 |
ATP-binding cassette, sub-family A (ABC1), member 1 |
multiple interactions increases expression |
ISO |
[Sirolimus co-treated with Tacrolimus] results in increased expression of ABCA1 protein Tacrolimus results in increased expression of ABCA1 mRNA |
CTD |
PMID:17016853 PMID:21865292 |
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NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
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ABCA1 |
ATP binding cassette subfamily A member 1 |
multiple interactions increases expression |
EXP ISO |
[Sirolimus co-treated with Tacrolimus] results in increased expression of ABCA1 protein Tacrolimus results in increased expression of ABCA1 mRNA |
CTD |
PMID:17016853 PMID:21865292 |
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NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155
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ABCB1 |
ATP binding cassette subfamily B member 1 |
increases response to substance decreases activity affects export multiple interactions increases export affects response to substance |
EXP |
ABCB1 gene SNP results in increased susceptibility to Tacrolimus Tacrolimus results in decreased activity of ABCB1 protein ABCB1 protein affects the export of Tacrolimus [Tacrolimus binds to ABCB1 protein] inhibits the reaction [azidoprazosin binds to ABCB1 protein]; [Tacrolimus results in decreased activity of ABCB1 protein] which results in decreased export of Dexamethasone; Verapamil affects the reaction [ABCB1 protein results in increased export of Tacrolimus] ABCB1 protein affects the susceptibility to Tacrolimus |
CTD |
PMID:1381629 PMID:11920757 PMID:12352921 PMID:15919446 PMID:15964336 PMID:20080907 More...
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NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
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Abcb11 |
ATP binding cassette subfamily B member 11 |
decreases activity |
ISO |
Tacrolimus results in decreased activity of ABCB11 protein |
CTD |
PMID:23956101 |
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NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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Abcb11 |
ATP-binding cassette, sub-family B (MDR/TAP), member 11 |
decreases activity |
ISO |
Tacrolimus results in decreased activity of ABCB11 protein |
CTD |
PMID:23956101 |
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NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,960
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ABCB11 |
ATP binding cassette subfamily B member 11 |
decreases activity |
EXP |
Tacrolimus results in decreased activity of ABCB11 protein |
CTD |
PMID:23956101 |
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NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324
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Abcb1a |
ATP binding cassette subfamily B member 1A |
affects export decreases activity multiple interactions increases response to substance increases export affects response to substance |
ISO |
ABCB1 protein affects the export of Tacrolimus Tacrolimus results in decreased activity of ABCB1 protein [Tacrolimus binds to ABCB1 protein] inhibits the reaction [azidoprazosin binds to ABCB1 protein]; [Tacrolimus results in decreased activity of ABCB1 protein] which results in decreased export of Dexamethasone; Verapamil affects the reaction [ABCB1 protein results in increased export of Tacrolimus] ABCB1 gene SNP results in increased susceptibility to Tacrolimus ABCB1 protein affects the susceptibility to Tacrolimus |
CTD |
PMID:1381629 PMID:11920757 PMID:12352921 PMID:15919446 PMID:15964336 PMID:20080907 More...
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Abcb1a |
ATP-binding cassette, sub-family B (MDR/TAP), member 1A |
increases response to substance decreases activity affects response to substance increases export multiple interactions affects export |
ISO |
ABCB1 gene SNP results in increased susceptibility to Tacrolimus Tacrolimus results in decreased activity of ABCB1 protein ABCB1 protein affects the susceptibility to Tacrolimus ABCB1 protein results in increased export of Tacrolimus [Tacrolimus binds to ABCB1 protein] inhibits the reaction [azidoprazosin binds to ABCB1 protein]; [Tacrolimus results in decreased activity of ABCB1 protein] which results in decreased export of Dexamethasone; Verapamil affects the reaction [ABCB1 protein results in increased export of Tacrolimus] ABCB1 protein affects the export of Tacrolimus |
CTD |
PMID:1381629 PMID:11920757 PMID:12352921 PMID:15919446 PMID:15964336 PMID:20080907 More...
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NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
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ACAA1 |
acetyl-CoA acyltransferase 1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ACAA1B mRNA |
CTD |
PMID:25270620 |
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NCBI chr 3:38,122,715...38,137,127
Ensembl chr 3:38,103,129...38,137,242
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Acaa1b |
acetyl-Coenzyme A acyltransferase 1B |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ACAA1B mRNA |
CTD |
PMID:25270620 |
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NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825
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Acaa1b |
acetyl-Coenzyme A acyltransferase 1B |
decreases expression |
EXP |
Tacrolimus results in decreased expression of ACAA1B mRNA |
CTD |
PMID:25270620 |
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NCBI chr 9:118,977,111...118,986,161
Ensembl chr 9:118,977,091...118,986,161
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Acadl |
acyl-CoA dehydrogenase, long chain |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ACADL mRNA |
CTD |
PMID:25270620 |
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NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
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Acadl |
acyl-Coenzyme A dehydrogenase, long-chain |
decreases expression |
EXP |
Tacrolimus results in decreased expression of ACADL mRNA |
CTD |
PMID:25270620 |
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NCBI chr 1:66,869,998...66,902,468
Ensembl chr 1:66,869,998...66,902,436
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ACADL |
acyl-CoA dehydrogenase long chain |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ACADL mRNA |
CTD |
PMID:25270620 |
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NCBI chr 2:210,187,923...210,225,447
Ensembl chr 2:210,187,126...210,225,447
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Ace2 |
angiotensin I converting enzyme 2 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of ACE2 mRNA |
CTD |
PMID:21865292 |
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NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
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Ace2 |
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ACE2 mRNA |
CTD |
PMID:21865292 |
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NCBI chr X:162,922,338...162,971,414
Ensembl chr X:162,922,328...162,971,416
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ACE2 |
angiotensin converting enzyme 2 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ACE2 mRNA |
CTD |
PMID:21865292 |
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NCBI chr X:15,518,197...15,607,211
Ensembl chr X:15,494,566...15,607,236
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Acp5 |
acid phosphatase 5, tartrate resistant |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 protein] |
CTD |
PMID:15207740 |
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NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
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Acp5 |
acid phosphatase 5, tartrate resistant |
multiple interactions |
EXP |
Tacrolimus inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 protein] |
CTD |
PMID:15207740 |
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NCBI chr 9:22,038,023...22,047,042
Ensembl chr 9:22,038,023...22,047,007
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ACP5 |
acid phosphatase 5, tartrate resistant |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 protein] |
CTD |
PMID:15207740 |
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NCBI chr19:11,574,660...11,578,975
Ensembl chr19:11,574,653...11,579,993
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Acta2 |
actin alpha 2, smooth muscle |
increases expression |
ISO |
Tacrolimus results in increased expression of ACTA2 protein |
CTD |
PMID:29362864 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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Acta2 |
actin alpha 2, smooth muscle, aorta |
increases expression |
EXP |
Tacrolimus results in increased expression of ACTA2 protein |
CTD |
PMID:29362864 |
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NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
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ACTA2 |
actin alpha 2, smooth muscle |
increases expression |
ISO |
Tacrolimus results in increased expression of ACTA2 protein |
CTD |
PMID:29362864 |
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NCBI chr10:88,935,074...88,991,397
Ensembl chr10:88,935,074...88,991,339
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Acvr1b |
activin A receptor type 1B |
multiple interactions |
ISO |
[Tacrolimus inhibits the reaction [FKBP1A protein binds to ACVR1B protein]] which results in decreased ubiquitination of ACVR1B protein; Tacrolimus inhibits the reaction [FKBP1A protein binds to and results in decreased activity of ACVR1B protein]; Tacrolimus inhibits the reaction [FKBP1A protein promotes the reaction [SMURF1 protein binds to SMAD7 protein binds to ACVR1B protein]] |
CTD |
PMID:16720724 |
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NCBI chr 7:132,286,266...132,329,679
Ensembl chr 7:132,286,275...132,329,673
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Acvr1b |
activin A receptor, type 1B |
multiple interactions |
ISO |
[Tacrolimus inhibits the reaction [FKBP1A protein binds to ACVR1B protein]] which results in decreased ubiquitination of ACVR1B protein; Tacrolimus inhibits the reaction [FKBP1A protein binds to and results in decreased activity of ACVR1B protein]; Tacrolimus inhibits the reaction [FKBP1A protein promotes the reaction [SMURF1 protein binds to SMAD7 protein binds to ACVR1B protein]] |
CTD |
PMID:16720724 |
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NCBI chr15:101,071,953...101,111,565
Ensembl chr15:101,071,948...101,111,565
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ACVR1B |
activin A receptor type 1B |
multiple interactions |
EXP |
[Tacrolimus inhibits the reaction [FKBP1A protein binds to ACVR1B protein]] which results in decreased ubiquitination of ACVR1B protein; Tacrolimus inhibits the reaction [FKBP1A protein binds to and results in decreased activity of ACVR1B protein]; Tacrolimus inhibits the reaction [FKBP1A protein promotes the reaction [SMURF1 protein binds to SMAD7 protein binds to ACVR1B protein]] |
CTD |
PMID:16720724 |
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NCBI chr12:51,951,699...51,997,078
Ensembl chr12:51,951,699...51,997,078
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Adamts1 |
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
increases expression |
EXP |
Tacrolimus results in increased expression of ADAMTS1 mRNA |
CTD |
PMID:21865292 |
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NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
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Adamts1 |
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of ADAMTS1 mRNA |
CTD |
PMID:21865292 |
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NCBI chr16:85,590,715...85,600,001
Ensembl chr16:85,590,715...85,600,001
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ADAMTS1 |
ADAM metallopeptidase with thrombospondin type 1 motif 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of ADAMTS1 mRNA |
CTD |
PMID:21865292 |
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NCBI chr21:26,835,755...26,845,409
Ensembl chr21:26,835,755...26,845,409
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Adamts2 |
ADAM metallopeptidase with thrombospondin type 1 motif, 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of ADAMTS2 mRNA |
CTD |
PMID:29362864 |
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NCBI chr10:34,920,996...35,126,465
Ensembl chr10:34,921,049...35,123,821
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Adamts2 |
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2 |
increases expression |
EXP |
Tacrolimus results in increased expression of ADAMTS2 mRNA |
CTD |
PMID:29362864 |
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NCBI chr11:50,492,912...50,698,400
Ensembl chr11:50,492,911...50,698,400
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ADAMTS2 |
ADAM metallopeptidase with thrombospondin type 1 motif 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of ADAMTS2 mRNA |
CTD |
PMID:29362864 |
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NCBI chr 5:179,110,853...179,345,461
Ensembl chr 5:179,110,853...179,345,461
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Adcy9 |
adenylate cyclase 9 |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]] |
CTD |
PMID:30607468 |
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NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066
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Adcy9 |
adenylate cyclase 9 |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]] |
CTD |
PMID:30607468 |
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NCBI chr16:4,102,750...4,255,094
Ensembl chr16:4,105,393...4,238,362
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ADCY9 |
adenylate cyclase 9 |
multiple interactions |
EXP |
Tacrolimus inhibits the reaction [Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]] |
CTD |
PMID:30607468 |
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NCBI chr16:3,953,387...4,116,442
Ensembl chr16:3,953,387...4,116,442
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Adra1d |
adrenoceptor alpha 1D |
increases expression |
EXP |
Tacrolimus results in increased expression of ADRA1D mRNA |
CTD |
PMID:21865292 |
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NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354
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Adra1d |
adrenergic receptor, alpha 1d |
increases expression |
ISO |
Tacrolimus results in increased expression of ADRA1D mRNA |
CTD |
PMID:21865292 |
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NCBI chr 2:131,387,277...131,404,417
Ensembl chr 2:131,387,770...131,404,203
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ADRA1D |
adrenoceptor alpha 1D |
increases expression |
ISO |
Tacrolimus results in increased expression of ADRA1D mRNA |
CTD |
PMID:21865292 |
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NCBI chr20:4,220,630...4,249,287
Ensembl chr20:4,220,630...4,249,287
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Aif1 |
allograft inflammatory factor 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of AIF1 mRNA |
CTD |
PMID:29362864 |
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NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
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Aif1 |
allograft inflammatory factor 1 |
increases expression |
EXP |
Tacrolimus results in increased expression of AIF1 mRNA |
CTD |
PMID:29362864 |
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NCBI chr17:35,389,962...35,395,050
Ensembl chr17:35,389,967...35,395,044
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AIF1 |
allograft inflammatory factor 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of AIF1 mRNA |
CTD |
PMID:29362864 |
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NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021
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Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ALDH1A1 mRNA |
CTD |
PMID:25270620 |
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NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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Aldh1a1 |
aldehyde dehydrogenase family 1, subfamily A1 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of ALDH1A1 mRNA |
CTD |
PMID:25270620 |
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NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829
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ALDH1A1 |
aldehyde dehydrogenase 1 family member A1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ALDH1A1 mRNA |
CTD |
PMID:25270620 |
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NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442
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Aldh1a7 |
aldehyde dehydrogenase family 1, subfamily A7 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of ALDH1A7 mRNA |
CTD |
PMID:25270620 |
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NCBI chr19:20,670,317...20,704,920
Ensembl chr19:20,670,317...20,704,926
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Aldh2 |
aldehyde dehydrogenase 2 family member |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ALDH2 mRNA |
CTD |
PMID:25270620 |
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NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
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Aldh2 |
aldehyde dehydrogenase 2, mitochondrial |
decreases expression |
EXP |
Tacrolimus results in decreased expression of ALDH2 mRNA |
CTD |
PMID:25270620 |
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NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887
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H |
ALDH2 |
aldehyde dehydrogenase 2 family member |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ALDH2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
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G |
R |
Aldh9a1 |
aldehyde dehydrogenase 9 family, member A1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ALDH9A1 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568
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G |
M |
Aldh9a1 |
aldehyde dehydrogenase 9, subfamily A1 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of ALDH9A1 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 1:167,177,532...167,196,099
Ensembl chr 1:167,177,560...167,196,101
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G |
H |
ALDH9A1 |
aldehyde dehydrogenase 9 family member A1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ALDH9A1 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 1:165,662,216...165,698,562
Ensembl chr 1:165,662,216...165,698,562
|
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G |
R |
Alg3 |
ALG3, alpha-1,3- mannosyltransferase |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ALG3 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr11:80,300,487...80,306,014
Ensembl chr11:80,300,498...80,307,912
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G |
M |
Alg3 |
asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase) |
decreases expression |
EXP |
Tacrolimus results in decreased expression of ALG3 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr16:20,424,208...20,429,515
Ensembl chr16:20,424,124...20,430,485
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G |
H |
ALG3 |
ALG3 alpha-1,3- mannosyltransferase |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ALG3 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 3:184,242,301...184,249,525
Ensembl chr 3:184,242,301...184,249,548
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G |
R |
Angptl6 |
angiopoietin-like 6 |
increases expression |
EXP |
Tacrolimus results in increased expression of ANGPTL6 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 8:19,413,617...19,419,925
Ensembl chr 8:19,413,619...19,419,925
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G |
M |
Angptl6 |
angiopoietin-like 6 |
increases expression |
ISO |
Tacrolimus results in increased expression of ANGPTL6 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 9:20,785,104...20,791,116
Ensembl chr 9:20,785,104...20,791,023
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G |
H |
ANGPTL6 |
angiopoietin like 6 |
increases expression |
ISO |
Tacrolimus results in increased expression of ANGPTL6 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr19:10,092,338...10,106,190
Ensembl chr19:10,092,338...10,102,678
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G |
R |
Ankrd1 |
ankyrin repeat domain 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of ANKRD1 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
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G |
M |
Ankrd1 |
ankyrin repeat domain 1 (cardiac muscle) |
increases expression |
EXP |
Tacrolimus results in increased expression of ANKRD1 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr19:36,089,365...36,097,244
Ensembl chr19:36,089,361...36,097,499
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G |
H |
ANKRD1 |
ankyrin repeat domain 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of ANKRD1 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr10:90,912,096...90,921,087
Ensembl chr10:90,912,096...90,921,087
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G |
R |
Ankrd34a |
ankyrin repeat domain 34A |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ANKRD34A mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 2:184,129,830...184,135,075
Ensembl chr 2:184,129,238...184,135,116
|
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G |
M |
Ankrd34a |
ankyrin repeat domain 34A |
decreases expression |
EXP |
Tacrolimus results in decreased expression of ANKRD34A mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 3:96,503,244...96,507,442
Ensembl chr 3:96,503,952...96,507,091
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G |
H |
ANKRD34A |
ankyrin repeat domain 34A |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ANKRD34A mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 1:145,959,441...145,964,575
Ensembl chr 1:145,959,441...145,964,575
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G |
R |
Anos1 |
anosmin 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of WFDC17 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr10:68,561,954...68,562,801
Ensembl chr10:68,561,954...68,562,801
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G |
H |
ANOS1 |
anosmin 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of WFDC17 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr X:8,528,874...8,732,137
Ensembl chr X:8,528,874...8,732,137
|
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G |
R |
Anpep |
alanyl aminopeptidase, membrane |
increases secretion |
EXP |
Tacrolimus results in increased secretion of ANPEP protein |
CTD |
PMID:7514309 |
|
NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789
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G |
M |
Anpep |
alanyl (membrane) aminopeptidase |
increases secretion |
ISO |
Tacrolimus results in increased secretion of ANPEP protein |
CTD |
PMID:7514309 |
|
NCBI chr 7:79,471,551...79,497,958
Ensembl chr 7:79,471,551...79,510,807
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G |
H |
ANPEP |
alanyl aminopeptidase, membrane |
increases secretion |
ISO |
Tacrolimus results in increased secretion of ANPEP protein |
CTD |
PMID:7514309 |
|
NCBI chr15:89,784,895...89,814,852
Ensembl chr15:89,784,895...89,815,401
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G |
R |
Anxa1 |
annexin A1 |
increases expression |
EXP |
Tacrolimus results in increased expression of ANXA1 |
CTD |
PMID:20484890 |
|
NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
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G |
M |
Anxa1 |
annexin A1 |
increases expression |
ISO |
Tacrolimus results in increased expression of ANXA1 |
CTD |
PMID:20484890 |
|
NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308
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G |
H |
ANXA1 |
annexin A1 |
increases expression |
ISO |
Tacrolimus results in increased expression of ANXA1 |
CTD |
PMID:20484890 |
|
NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393
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G |
R |
Aoc1 |
amine oxidase, copper containing 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of AOC1 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840
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G |
M |
Aoc1 |
amine oxidase, copper-containing 1 |
increases expression |
EXP |
Tacrolimus results in increased expression of AOC1 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 6:48,872,189...48,886,122
Ensembl chr 6:48,849,830...48,886,122
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G |
H |
AOC1 |
amine oxidase copper containing 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of AOC1 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 7:150,852,120...150,861,504
Ensembl chr 7:150,824,627...150,861,504
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G |
R |
Areg |
amphiregulin |
increases expression |
EXP |
Tacrolimus results in increased expression of AREG mRNA |
CTD |
PMID:21865292 |
|
NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
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G |
M |
Areg |
amphiregulin |
increases expression |
ISO |
Tacrolimus results in increased expression of AREG mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291
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G |
H |
AREG |
amphiregulin |
increases expression |
ISO |
Tacrolimus results in increased expression of AREG mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005
|
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G |
R |
Arfrp1 |
ADP-ribosylation factor related protein 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of ARFRP1 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 3:168,466,351...168,473,960
Ensembl chr 3:168,466,496...168,473,914
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G |
M |
Arfrp1 |
ADP-ribosylation factor related protein 1 |
increases expression |
EXP |
Tacrolimus results in increased expression of ARFRP1 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 2:180,999,483...181,007,197
Ensembl chr 2:180,999,483...181,007,197
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G |
H |
ARFRP1 |
ADP ribosylation factor related protein 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of ARFRP1 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr20:63,698,647...63,707,976
Ensembl chr20:63,698,642...63,708,025
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G |
R |
Arhgap45 |
Rho GTPase activating protein 45 |
increases expression |
ISO |
Tacrolimus results in increased expression of ARHGAP45 mRNA |
CTD |
PMID:21621594 |
|
NCBI chr 7:9,674,873...9,690,286
Ensembl chr 7:9,674,897...9,690,268
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G |
M |
Arhgap45 |
Rho GTPase activating protein 45 |
increases expression |
EXP |
Tacrolimus results in increased expression of ARHGAP45 mRNA |
CTD |
PMID:21621594 |
|
NCBI chr10:79,852,505...79,867,305
Ensembl chr10:79,852,487...79,867,306
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G |
H |
ARHGAP45 |
Rho GTPase activating protein 45 |
increases expression |
ISO |
Tacrolimus results in increased expression of ARHGAP45 mRNA |
CTD |
PMID:21621594 |
|
NCBI chr19:1,065,959...1,086,628
Ensembl chr19:1,065,923...1,086,628
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G |
R |
Arhgef11 |
Rho guanine nucleotide exchange factor 11 |
increases expression |
ISO |
Tacrolimus results in increased expression of ARHGEF11 mRNA |
CTD |
PMID:29380240 |
|
NCBI chr 2:173,074,383...173,195,962
Ensembl chr 2:173,074,368...173,196,010
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G |
M |
Arhgef11 |
Rho guanine nucleotide exchange factor (GEF) 11 |
increases expression |
ISO |
Tacrolimus results in increased expression of ARHGEF11 mRNA |
CTD |
PMID:29380240 |
|
NCBI chr 3:87,524,855...87,645,346
Ensembl chr 3:87,524,866...87,645,341
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G |
H |
ARHGEF11 |
Rho guanine nucleotide exchange factor 11 |
increases expression |
EXP |
Tacrolimus results in increased expression of ARHGEF11 mRNA |
CTD |
PMID:29380240 |
|
NCBI chr 1:156,934,840...157,046,903
Ensembl chr 1:156,934,840...157,045,742
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G |
R |
Arpc5 |
actin related protein 2/3 complex, subunit 5 |
increases expression |
ISO |
Tacrolimus results in increased expression of ARPC5 mRNA |
CTD |
PMID:29380240 |
|
NCBI chr13:64,904,504...64,913,413
Ensembl chr13:64,887,136...64,913,410
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G |
M |
Arpc5 |
actin related protein 2/3 complex, subunit 5 |
increases expression |
ISO |
Tacrolimus results in increased expression of ARPC5 mRNA |
CTD |
PMID:29380240 |
|
NCBI chr 1:152,642,293...152,651,331
Ensembl chr 1:152,642,293...152,651,348
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G |
H |
ARPC5 |
actin related protein 2/3 complex subunit 5 |
increases expression |
EXP |
Tacrolimus results in increased expression of ARPC5 mRNA |
CTD |
PMID:29380240 |
|
NCBI chr 1:183,620,846...183,635,783
Ensembl chr 1:183,620,846...183,635,783
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G |
R |
Arv1 |
ARV1 homolog, fatty acid homeostasis modulator |
increases expression |
ISO |
Tacrolimus results in increased expression of ARV1 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr19:52,692,337...52,704,156
Ensembl chr19:52,692,337...52,704,156
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G |
M |
Arv1 |
ARV1 homolog, fatty acid homeostasis modulator |
increases expression |
EXP |
Tacrolimus results in increased expression of ARV1 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 8:125,448,765...125,469,533
Ensembl chr 8:125,448,878...125,460,862
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G |
H |
ARV1 |
ARV1 homolog, fatty acid homeostasis modulator |
increases expression |
ISO |
Tacrolimus results in increased expression of ARV1 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 1:230,979,094...231,000,733
Ensembl chr 1:230,978,981...231,000,733
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G |
R |
Asxl3 |
ASXL transcriptional regulator 3 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ASXL3 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr18:13,593,529...13,766,324
Ensembl chr18:13,593,985...13,762,427
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G |
M |
Asxl3 |
ASXL transcriptional regulator 3 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of ASXL3 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr18:22,477,195...22,663,284
Ensembl chr18:22,477,303...22,663,284
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G |
H |
ASXL3 |
ASXL transcriptional regulator 3 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ASXL3 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr18:33,578,219...33,751,195
Ensembl chr18:33,578,219...33,751,195
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G |
R |
Atf3 |
activating transcription factor 3 |
increases expression |
ISO |
Tacrolimus results in increased expression of ATF3 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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G |
M |
Atf3 |
activating transcription factor 3 |
increases expression |
EXP |
Tacrolimus results in increased expression of ATF3 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
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G |
H |
ATF3 |
activating transcription factor 3 |
increases expression |
ISO |
Tacrolimus results in increased expression of ATF3 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
|
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G |
R |
Atf4 |
activating transcription factor 4 |
increases expression |
ISO |
Tacrolimus results in increased expression of ATF4 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
M |
Atf4 |
activating transcription factor 4 |
increases expression |
EXP |
Tacrolimus results in increased expression of ATF4 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742
|
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G |
H |
ATF4 |
activating transcription factor 4 |
increases expression |
ISO |
Tacrolimus results in increased expression of ATF4 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683
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G |
R |
Atf6 |
activating transcription factor 6 |
increases expression |
ISO |
Tacrolimus results in increased expression of ATF6 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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G |
M |
Atf6 |
activating transcription factor 6 |
increases expression |
EXP |
Tacrolimus results in increased expression of ATF6 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340
|
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G |
H |
ATF6 |
activating transcription factor 6 |
increases expression |
ISO |
Tacrolimus results in increased expression of ATF6 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574
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G |
R |
Atp1b1 |
ATPase Na+/K+ transporting subunit beta 1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ATP1B1 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
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G |
M |
Atp1b1 |
ATPase, Na+/K+ transporting, beta 1 polypeptide |
decreases expression |
EXP |
Tacrolimus results in decreased expression of ATP1B1 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 1:164,264,668...164,285,924
Ensembl chr 1:164,264,678...164,285,924
|
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G |
H |
ATP1B1 |
ATPase Na+/K+ transporting subunit beta 1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ATP1B1 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,310,992
|
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G |
R |
Atp1b3 |
ATPase Na+/K+ transporting subunit beta 3 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ATP1B3 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 8:96,910,265...96,941,592
Ensembl chr 8:96,910,309...96,941,598
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G |
M |
Atp1b3 |
ATPase, Na+/K+ transporting, beta 3 polypeptide |
decreases expression |
EXP |
Tacrolimus results in decreased expression of ATP1B3 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 9:96,214,708...96,246,484
Ensembl chr 9:96,214,708...96,246,495
|
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G |
H |
ATP1B3 |
ATPase Na+/K+ transporting subunit beta 3 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ATP1B3 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 3:141,876,643...141,926,549
Ensembl chr 3:141,876,124...141,926,549
|
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G |
R |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of ATP2A2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
|
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G |
M |
Atp2a2 |
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
increases expression |
EXP |
Tacrolimus results in increased expression of ATP2A2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 5:122,591,576...122,640,288
Ensembl chr 5:122,591,576...122,640,288
|
|
G |
H |
ATP2A2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of ATP2A2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr12:110,281,247...110,351,093
Ensembl chr12:110,280,756...110,351,093
|
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G |
R |
B2m |
beta-2 microglobulin |
increases expression |
ISO |
Tacrolimus results in increased expression of B2M mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
|
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G |
M |
B2m |
beta-2 microglobulin |
increases expression |
EXP |
Tacrolimus results in increased expression of B2M mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564
|
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G |
H |
B2M |
beta-2-microglobulin |
increases expression |
ISO |
Tacrolimus results in increased expression of B2M mRNA |
CTD |
PMID:29362864 |
|
NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851
|
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G |
R |
Bad |
BCL2-associated agonist of cell death |
multiple interactions |
EXP ISO |
Tacrolimus inhibits the reaction [Ammonium Chloride results in decreased phosphorylation of BAD protein] Tacrolimus inhibits the reaction [Rotenone results in decreased phosphorylation of BAD protein] |
CTD |
PMID:15036616 PMID:15280438 |
|
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
|
|
G |
M |
Bad |
BCL2-associated agonist of cell death |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [Ammonium Chloride results in decreased phosphorylation of BAD protein] Tacrolimus inhibits the reaction [Rotenone results in decreased phosphorylation of BAD protein] |
CTD |
PMID:15036616 PMID:15280438 |
|
NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
|
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G |
H |
BAD |
BCL2 associated agonist of cell death |
multiple interactions |
ISO EXP |
Tacrolimus inhibits the reaction [Ammonium Chloride results in decreased phosphorylation of BAD protein] Tacrolimus inhibits the reaction [Rotenone results in decreased phosphorylation of BAD protein] |
CTD |
PMID:15036616 PMID:15280438 |
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NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
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G |
R |
Batf3 |
basic leucine zipper ATF-like transcription factor 3 |
increases expression |
ISO |
Tacrolimus results in increased expression of BATF3 mRNA |
CTD |
PMID:29362864 |
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NCBI chr13:102,689,657...102,701,241
Ensembl chr13:102,689,657...102,701,139
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G |
M |
Batf3 |
basic leucine zipper transcription factor, ATF-like 3 |
increases expression |
EXP |
Tacrolimus results in increased expression of BATF3 mRNA |
CTD |
PMID:29362864 |
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NCBI chr 1:190,830,611...190,841,140
Ensembl chr 1:190,830,044...190,841,142
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G |
H |
BATF3 |
basic leucine zipper ATF-like transcription factor 3 |
increases expression |
ISO |
Tacrolimus results in increased expression of BATF3 mRNA |
CTD |
PMID:29362864 |
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NCBI chr 1:212,686,417...212,699,840
Ensembl chr 1:212,686,417...212,699,840
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G |
R |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions increases expression |
ISO EXP |
Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BAX protein] Tacrolimus results in increased expression of BAX protein [Tacrolimus co-treated with 3-nitropropionic acid] affects the localization of BAX protein |
CTD |
PMID:10205001 PMID:15571979 PMID:27606422 PMID:35033536 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
M |
Bax |
BCL2-associated X protein |
multiple interactions increases expression |
EXP ISO |
Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BAX protein] Tacrolimus results in increased expression of BAX protein [Tacrolimus co-treated with 3-nitropropionic acid] affects the localization of BAX protein |
CTD |
PMID:10205001 PMID:15571979 PMID:27606422 PMID:35033536 |
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NCBI chr 7:45,111,119...45,116,344
Ensembl chr 7:45,111,121...45,116,322
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G |
H |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions increases expression |
ISO EXP |
Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BAX protein] Tacrolimus results in increased expression of BAX protein [Tacrolimus co-treated with 3-nitropropionic acid] affects the localization of BAX protein |
CTD |
PMID:10205001 PMID:15571979 PMID:27606422 PMID:35033536 |
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NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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G |
R |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions decreases expression increases expression |
ISO EXP |
Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in decreased expression of BCL2 protein] Tacrolimus results in decreased expression of BCL2 protein [Tacrolimus co-treated with 3-nitropropionic acid] affects the localization of BCL2 protein Tacrolimus results in increased expression of BCL2 protein |
CTD |
PMID:10205001 PMID:15571979 PMID:27606422 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
M |
Bcl2 |
B cell leukemia/lymphoma 2 |
multiple interactions decreases expression increases expression |
EXP ISO |
Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in decreased expression of BCL2 protein] Tacrolimus results in decreased expression of BCL2 protein [Tacrolimus co-treated with 3-nitropropionic acid] affects the localization of BCL2 protein Tacrolimus results in increased expression of BCL2 protein |
CTD |
PMID:10205001 PMID:15571979 PMID:27606422 |
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NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
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G |
H |
BCL2 |
BCL2 apoptosis regulator |
multiple interactions decreases expression increases expression |
ISO |
Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in decreased expression of BCL2 protein] Tacrolimus results in decreased expression of BCL2 protein [Tacrolimus co-treated with 3-nitropropionic acid] affects the localization of BCL2 protein Tacrolimus results in increased expression of BCL2 protein |
CTD |
PMID:10205001 PMID:15571979 PMID:27606422 |
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NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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G |
R |
Bcl2l1 |
Bcl2-like 1 |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [Superantigens results in increased expression of BCL2L1 protein] |
CTD |
PMID:10532544 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
M |
Bcl2l1 |
BCL2-like 1 |
multiple interactions |
EXP |
Tacrolimus inhibits the reaction [Superantigens results in increased expression of BCL2L1 protein] |
CTD |
PMID:10532544 |
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NCBI chr 2:152,600,652...152,675,723
Ensembl chr 2:152,622,588...152,673,648
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G |
H |
BCL2L1 |
BCL2 like 1 |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [Superantigens results in increased expression of BCL2L1 protein] |
CTD |
PMID:10532544 |
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NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
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G |
R |
Bcl3 |
BCL3, transcription coactivator |
increases expression |
ISO |
Tacrolimus results in increased expression of BCL3 mRNA |
CTD |
PMID:23958496 |
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NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
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G |
M |
Bcl3 |
B cell leukemia/lymphoma 3 |
increases expression |
EXP |
Tacrolimus results in increased expression of BCL3 mRNA |
CTD |
PMID:23958496 |
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NCBI chr 7:19,542,387...19,556,691
Ensembl chr 7:19,542,387...19,556,695
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G |
H |
BCL3 |
BCL3 transcription coactivator |
increases expression |
ISO |
Tacrolimus results in increased expression of BCL3 mRNA |
CTD |
PMID:23958496 |
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NCBI chr19:44,747,705...44,760,044
Ensembl chr19:44,747,705...44,760,044
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G |
R |
Bdnf |
brain-derived neurotrophic factor |
multiple interactions |
EXP |
Tacrolimus inhibits the reaction [decamethrin results in increased expression of BDNF exon]; Tacrolimus promotes the reaction [U 0126 inhibits the reaction [decamethrin results in increased expression of BDNF exon]]; U 0126 promotes the reaction [Tacrolimus inhibits the reaction [decamethrin results in increased expression of BDNF exon]] |
CTD |
PMID:22079160 |
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NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
M |
Bdnf |
brain derived neurotrophic factor |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [decamethrin results in increased expression of BDNF exon]; Tacrolimus promotes the reaction [U 0126 inhibits the reaction [decamethrin results in increased expression of BDNF exon]]; U 0126 promotes the reaction [Tacrolimus inhibits the reaction [decamethrin results in increased expression of BDNF exon]] |
CTD |
PMID:22079160 |
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NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
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G |
H |
BDNF |
brain derived neurotrophic factor |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [decamethrin results in increased expression of BDNF exon]; Tacrolimus promotes the reaction [U 0126 inhibits the reaction [decamethrin results in increased expression of BDNF exon]]; U 0126 promotes the reaction [Tacrolimus inhibits the reaction [decamethrin results in increased expression of BDNF exon]] |
CTD |
PMID:22079160 |
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NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
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G |
R |
Birc3 |
baculoviral IAP repeat-containing 3 |
increases expression |
EXP |
Tacrolimus results in increased expression of BIRC3 mRNA |
CTD |
PMID:21865292 |
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NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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G |
M |
Birc3 |
baculoviral IAP repeat-containing 3 |
increases expression |
ISO |
Tacrolimus results in increased expression of BIRC3 mRNA |
CTD |
PMID:21865292 |
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NCBI chr 9:7,848,698...7,873,199
Ensembl chr 9:7,848,700...7,873,187
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G |
H |
BIRC3 |
baculoviral IAP repeat containing 3 |
increases expression |
ISO |
Tacrolimus results in increased expression of BIRC3 mRNA |
CTD |
PMID:21865292 |
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NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,450...102,339,403
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G |
R |
Birc5 |
baculoviral IAP repeat-containing 5 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of BIRC5 mRNA |
CTD |
PMID:16574167 |
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NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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G |
M |
Birc5 |
baculoviral IAP repeat-containing 5 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of BIRC5 mRNA |
CTD |
PMID:16574167 |
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NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569
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G |
H |
BIRC5 |
baculoviral IAP repeat containing 5 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of BIRC5 mRNA |
CTD |
PMID:16574167 |
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NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
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G |
R |
Bmp7 |
bone morphogenetic protein 7 |
multiple interactions decreases expression |
EXP |
Ramipril inhibits the reaction [Tacrolimus results in decreased expression of BMP7 protein]; valsartan inhibits the reaction [Tacrolimus results in decreased expression of BMP7 protein] |
CTD |
PMID:17703430 |
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NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
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G |
M |
Bmp7 |
bone morphogenetic protein 7 |
multiple interactions decreases expression |
ISO |
Ramipril inhibits the reaction [Tacrolimus results in decreased expression of BMP7 protein]; valsartan inhibits the reaction [Tacrolimus results in decreased expression of BMP7 protein] |
CTD |
PMID:17703430 |
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NCBI chr 2:172,709,805...172,782,114
Ensembl chr 2:172,709,805...172,782,114
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G |
H |
BMP7 |
bone morphogenetic protein 7 |
multiple interactions decreases expression |
ISO |
Ramipril inhibits the reaction [Tacrolimus results in decreased expression of BMP7 protein]; valsartan inhibits the reaction [Tacrolimus results in decreased expression of BMP7 protein] |
CTD |
PMID:17703430 |
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NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641
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G |
R |
Btg2 |
BTG anti-proliferation factor 2 |
increases expression |
EXP |
Tacrolimus results in increased expression of BTG2 mRNA |
CTD |
PMID:21865292 |
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NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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G |
M |
Btg2 |
BTG anti-proliferation factor 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of BTG2 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 1:134,002,603...134,006,893
Ensembl chr 1:134,002,908...134,006,858
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G |
H |
BTG2 |
BTG anti-proliferation factor 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of BTG2 mRNA |
CTD |
PMID:21865292 |
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NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602
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G |
R |
Btnl9 |
butyrophilin-like 9 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of BTNL9 mRNA |
CTD |
PMID:29362864 |
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NCBI chr10:33,466,059...33,489,229
Ensembl chr10:33,470,536...33,489,025
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G |
M |
Btnl9 |
butyrophilin-like 9 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of BTNL9 mRNA |
CTD |
PMID:29362864 |
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NCBI chr11:49,059,152...49,077,916
Ensembl chr11:49,056,412...49,077,986
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G |
H |
BTNL9 |
butyrophilin like 9 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of BTNL9 mRNA |
CTD |
PMID:29362864 |
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NCBI chr 5:181,040,266...181,061,521
Ensembl chr 5:181,040,225...181,061,521
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G |
R |
C1qa |
complement C1q A chain |
increases expression |
ISO |
Tacrolimus results in increased expression of C1QA mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534
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G |
M |
C1qa |
complement component 1, q subcomponent, alpha polypeptide |
increases expression |
EXP |
Tacrolimus results in increased expression of C1QA mRNA |
CTD |
PMID:29362864 |
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NCBI chr 4:136,623,227...136,626,155
Ensembl chr 4:136,623,228...136,626,114
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G |
H |
C1QA |
complement C1q A chain |
increases expression |
ISO |
Tacrolimus results in increased expression of C1QA mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 1:22,636,463...22,639,678
Ensembl chr 1:22,635,077...22,639,678
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G |
R |
C1qb |
complement C1q B chain |
increases expression |
ISO |
Tacrolimus results in increased expression of C1QB mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407
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G |
M |
C1qb |
complement component 1, q subcomponent, beta polypeptide |
increases expression |
EXP |
Tacrolimus results in increased expression of C1QB mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 4:136,607,437...136,613,511
Ensembl chr 4:136,607,440...136,613,498
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G |
H |
C1QB |
complement C1q B chain |
increases expression |
ISO |
Tacrolimus results in increased expression of C1QB mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 1:22,653,236...22,661,637
Ensembl chr 1:22,652,762...22,661,637
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G |
R |
C1qc |
complement C1q C chain |
increases expression |
ISO |
Tacrolimus results in increased expression of C1QC mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 5:149,127,424...149,130,732
Ensembl chr 5:149,127,415...149,131,017
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G |
M |
C1qc |
complement component 1, q subcomponent, C chain |
increases expression |
EXP |
Tacrolimus results in increased expression of C1QC mRNA |
CTD |
PMID:29362864 |
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NCBI chr 4:136,617,112...136,620,242
Ensembl chr 4:136,617,115...136,620,376
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G |
H |
C1QC |
complement C1q C chain |
increases expression |
ISO |
Tacrolimus results in increased expression of C1QC mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 1:22,643,633...22,648,108
Ensembl chr 1:22,643,014...22,648,110
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G |
M |
C1ra |
complement component 1, r subcomponent A |
increases expression |
EXP |
Tacrolimus results in increased expression of C1RA mRNA |
CTD |
PMID:29362864 |
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NCBI chr 6:124,489,580...124,500,399
Ensembl chr 6:124,489,364...124,500,402
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G |
R |
C2 |
complement C2 |
increases expression |
EXP |
Tacrolimus results in increased expression of C2 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505
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G |
M |
C2 |
complement component 2 (within H-2S) |
increases expression |
ISO |
Tacrolimus results in increased expression of C2 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr17:35,081,578...35,101,076
Ensembl chr17:35,081,580...35,117,241
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G |
H |
C2 |
complement C2 |
increases expression |
ISO |
Tacrolimus results in increased expression of C2 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 6:31,897,783...31,945,672
Ensembl chr 6:31,897,785...31,945,673
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G |
R |
C3 |
complement C3 |
increases expression |
EXP ISO |
Tacrolimus results in increased expression of C3 mRNA |
CTD |
PMID:21865292 PMID:29362864 |
|
NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
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G |
M |
C3 |
complement component 3 |
increases expression |
ISO EXP |
Tacrolimus results in increased expression of C3 mRNA |
CTD |
PMID:21865292 PMID:29362864 |
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NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136
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G |
H |
C3 |
complement C3 |
increases expression |
ISO |
Tacrolimus results in increased expression of C3 mRNA |
CTD |
PMID:21865292 PMID:29362864 |
|
NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
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G |
R |
C4b |
complement C4B (Chido blood group) |
increases expression |
EXP |
Tacrolimus results in increased expression of C4B mRNA |
CTD |
PMID:21865292 |
|
NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681
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G |
M |
C4b |
complement component 4B (Chido blood group) |
increases expression |
ISO |
Tacrolimus results in increased expression of C4B mRNA |
CTD |
PMID:21865292 |
|
NCBI chr17:34,947,249...34,962,876
Ensembl chr17:34,947,354...34,962,856
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G |
H |
C4B |
complement C4B (Chido blood group) |
increases expression |
ISO |
Tacrolimus results in increased expression of C4B mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 6:32,014,795...32,035,418
Ensembl chr 6:32,014,795...32,035,418
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G |
R |
Calb1 |
calbindin 1 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of CALB1 mRNA; Tacrolimus results in decreased expression of CALB1 protein |
CTD |
PMID:14978156 PMID:21865292 |
|
NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431
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G |
M |
Calb1 |
calbindin 1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of CALB1 mRNA; Tacrolimus results in decreased expression of CALB1 protein |
CTD |
PMID:14978156 PMID:21865292 |
|
NCBI chr 4:15,881,264...15,906,709
Ensembl chr 4:15,881,264...15,908,064
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G |
H |
CALB1 |
calbindin 1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of CALB1 mRNA; Tacrolimus results in decreased expression of CALB1 protein |
CTD |
PMID:14978156 PMID:21865292 |
|
NCBI chr 8:90,058,608...90,082,879
Ensembl chr 8:90,058,608...90,095,475
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G |
R |
Calcr |
calcitonin receptor |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [TNFSF11 protein results in increased expression of CALCR mRNA] |
CTD |
PMID:21869564 |
|
NCBI chr 4:31,661,270...31,736,392
Ensembl chr 4:31,661,273...31,736,392
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G |
M |
Calcr |
calcitonin receptor |
multiple interactions |
EXP |
Tacrolimus inhibits the reaction [TNFSF11 protein results in increased expression of CALCR mRNA] |
CTD |
PMID:21869564 |
|
NCBI chr 6:3,685,678...3,764,713
Ensembl chr 6:3,685,680...3,764,714
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G |
H |
CALCR |
calcitonin receptor |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [TNFSF11 protein results in increased expression of CALCR mRNA] |
CTD |
PMID:21869564 |
|
NCBI chr 7:93,424,486...93,574,724
Ensembl chr 7:93,424,486...93,574,730
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G |
R |
Calr |
calreticulin |
increases expression |
ISO |
Tacrolimus results in increased expression of CALR mRNA |
CTD |
PMID:25270620 |
|
NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
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G |
M |
Calr |
calreticulin |
increases expression |
EXP |
Tacrolimus results in increased expression of CALR mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563
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G |
H |
CALR |
calreticulin |
increases expression |
ISO |
Tacrolimus results in increased expression of CALR mRNA |
CTD |
PMID:25270620 |
|
NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489
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G |
R |
Camk1d |
calcium/calmodulin-dependent protein kinase ID |
increases expression |
ISO |
Tacrolimus results in increased expression of CAMK1D mRNA |
CTD |
PMID:23958496 |
|
NCBI chr17:72,581,899...72,982,704
Ensembl chr17:72,581,979...72,980,556
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G |
M |
Camk1d |
calcium/calmodulin-dependent protein kinase ID |
increases expression |
EXP |
Tacrolimus results in increased expression of CAMK1D mRNA |
CTD |
PMID:23958496 |
|
NCBI chr 2:5,298,268...5,719,665
Ensembl chr 2:5,298,268...5,719,326
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G |
H |
CAMK1D |
calcium/calmodulin dependent protein kinase ID |
increases expression |
ISO |
Tacrolimus results in increased expression of CAMK1D mRNA |
CTD |
PMID:23958496 |
|
NCBI chr10:12,349,547...12,835,545
Ensembl chr10:12,349,547...12,835,545
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G |
R |
Capg |
capping actin protein, gelsolin like |
increases expression |
EXP |
Tacrolimus results in increased expression of CAPG mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856
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G |
M |
Capg |
capping protein (actin filament), gelsolin-like |
increases expression |
ISO |
Tacrolimus results in increased expression of CAPG mRNA |
CTD |
PMID:21865292 |
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NCBI chr 6:72,515,265...72,539,966
Ensembl chr 6:72,521,374...72,539,966
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G |
H |
CAPG |
capping actin protein, gelsolin like |
increases expression |
ISO |
Tacrolimus results in increased expression of CAPG mRNA |
CTD |
PMID:21865292 |
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NCBI chr 2:85,391,602...85,419,540
Ensembl chr 2:85,394,753...85,418,432
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G |
P |
CASP3 |
caspase 3 |
increases activity |
EXP |
Tacrolimus results in increased activity of CASP3 protein |
CTD |
PMID:14675044 |
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NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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G |
R |
Casp3 |
caspase 3 |
multiple interactions increases cleavage increases activity |
ISO EXP |
Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein] Tacrolimus results in increased cleavage of CASP3 protein Tacrolimus results in increased activity of CASP3 protein MK0626 inhibits the reaction [Tacrolimus results in increased activity of CASP3 protein]; NGF protein inhibits the reaction [Tacrolimus results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [3-nitropropionic acid results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Oxygen deficiency results in increased activity of CASP3 protein] Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [S-Nitrosoglutathione results in increased activity of CASP3 protein] |
CTD |
PMID:10205001 PMID:12642403 PMID:12871656 PMID:12892836 PMID:15207740 PMID:15548389 PMID:15571979 PMID:17166486 PMID:17385075 PMID:20149694 PMID:24959755 PMID:27606422 PMID:35033536 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
M |
Casp3 |
caspase 3 |
multiple interactions increases cleavage increases activity |
ISO EXP |
Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein] Tacrolimus results in increased cleavage of CASP3 protein Tacrolimus results in increased activity of CASP3 protein MK0626 inhibits the reaction [Tacrolimus results in increased activity of CASP3 protein]; NGF protein inhibits the reaction [Tacrolimus results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [3-nitropropionic acid results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Oxygen deficiency results in increased activity of CASP3 protein] Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [S-Nitrosoglutathione results in increased activity of CASP3 protein] |
CTD |
PMID:10205001 PMID:12642403 PMID:12871656 PMID:12892836 PMID:15207740 PMID:15548389 PMID:15571979 PMID:17166486 PMID:17385075 PMID:20149694 PMID:24959755 PMID:27606422 PMID:35033536 More...
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NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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G |
H |
CASP3 |
caspase 3 |
multiple interactions increases cleavage increases activity |
EXP ISO |
Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein] Tacrolimus results in increased cleavage of CASP3 protein Tacrolimus results in increased activity of CASP3 protein MK0626 inhibits the reaction [Tacrolimus results in increased activity of CASP3 protein]; NGF protein inhibits the reaction [Tacrolimus results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [3-nitropropionic acid results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Oxygen deficiency results in increased activity of CASP3 protein] Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [S-Nitrosoglutathione results in increased activity of CASP3 protein] |
CTD |
PMID:10205001 PMID:12642403 PMID:12871656 PMID:12892836 PMID:15207740 PMID:15548389 PMID:15571979 PMID:17166486 PMID:17385075 PMID:20149694 PMID:24959755 PMID:27606422 PMID:35033536 More...
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NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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G |
R |
Casp8 |
caspase 8 |
multiple interactions increases expression |
ISO |
Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP8 protein] Tacrolimus results in increased expression of CASP8 protein |
CTD |
PMID:15548389 PMID:27606422 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
M |
Casp8 |
caspase 8 |
multiple interactions increases expression |
ISO EXP |
Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP8 protein] Tacrolimus results in increased expression of CASP8 protein |
CTD |
PMID:15548389 PMID:27606422 |
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NCBI chr 1:58,834,398...58,886,662
Ensembl chr 1:58,834,533...58,886,662
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G |
H |
CASP8 |
caspase 8 |
multiple interactions increases expression |
EXP ISO |
Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP8 protein] Tacrolimus results in increased expression of CASP8 protein |
CTD |
PMID:15548389 PMID:27606422 |
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NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,361,836
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G |
R |
Casp9 |
caspase 9 |
multiple interactions increases expression |
ISO |
Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP9 protein] Tacrolimus results in increased expression of CASP9 protein |
CTD |
PMID:15548389 PMID:27606422 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
M |
Casp9 |
caspase 9 |
multiple interactions increases expression |
ISO EXP |
Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP9 protein] Tacrolimus results in increased expression of CASP9 protein |
CTD |
PMID:15548389 PMID:27606422 |
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NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
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G |
H |
CASP9 |
caspase 9 |
multiple interactions increases expression |
EXP ISO |
Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP9 protein] Tacrolimus results in increased expression of CASP9 protein |
CTD |
PMID:15548389 PMID:27606422 |
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NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
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G |
R |
Cat |
catalase |
increases expression decreases response to substance |
EXP ISO |
Tacrolimus results in increased expression of CAT protein CAT protein results in decreased susceptibility to Tacrolimus |
CTD |
PMID:14675044 PMID:18766458 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
M |
Cat |
catalase |
increases expression decreases response to substance |
ISO |
Tacrolimus results in increased expression of CAT protein CAT protein results in decreased susceptibility to Tacrolimus |
CTD |
PMID:14675044 PMID:18766458 |
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NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
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G |
H |
CAT |
catalase |
increases expression decreases response to substance |
ISO EXP |
Tacrolimus results in increased expression of CAT protein CAT protein results in decreased susceptibility to Tacrolimus |
CTD |
PMID:14675044 PMID:18766458 |
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NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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G |
R |
Cbll1 |
Cbl proto-oncogene like 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of CBLL1 mRNA |
CTD |
PMID:21621594 |
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NCBI chr 6:48,071,190...48,086,174
Ensembl chr 6:48,071,190...48,086,444
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G |
M |
Cbll1 |
Casitas B-lineage lymphoma-like 1 |
increases expression |
EXP |
Tacrolimus results in increased expression of CBLL1 mRNA |
CTD |
PMID:21621594 |
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NCBI chr12:31,534,828...31,550,675
Ensembl chr12:31,534,828...31,549,615
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G |
H |
CBLL1 |
Cbl proto-oncogene like 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of CBLL1 mRNA |
CTD |
PMID:21621594 |
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NCBI chr 7:107,744,142...107,761,667
Ensembl chr 7:107,743,073...107,761,667
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G |
R |
Ccdc88b |
coiled-coil domain containing 88B |
increases expression |
ISO |
Tacrolimus results in increased expression of CCDC88B mRNA |
CTD |
PMID:29362864 |
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NCBI chr 1:204,036,913...204,052,878
Ensembl chr 1:204,036,918...204,052,970
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G |
M |
Ccdc88b |
coiled-coil domain containing 88B |
increases expression |
EXP |
Tacrolimus results in increased expression of CCDC88B mRNA |
CTD |
PMID:29362864 |
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NCBI chr19:6,821,991...6,835,586
Ensembl chr19:6,821,991...6,835,579
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G |
H |
CCDC88B |
coiled-coil domain containing 88B |
increases expression |
ISO |
Tacrolimus results in increased expression of CCDC88B mRNA |
CTD |
PMID:29362864 |
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NCBI chr11:64,340,204...64,357,534
Ensembl chr11:64,340,204...64,357,534
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G |
R |
Ccl11 |
C-C motif chemokine ligand 11 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of CCL11 mRNA |
CTD |
PMID:15948978 |
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NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
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G |
M |
Ccl11 |
chemokine (C-C motif) ligand 11 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of CCL11 mRNA |
CTD |
PMID:15948978 |
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NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
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G |
H |
CCL11 |
C-C motif chemokine ligand 11 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of CCL11 mRNA |
CTD |
PMID:15948978 |
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NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334
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G |
H |
CCL15 |
C-C motif chemokine ligand 15 |
increases expression |
ISO |
Tacrolimus results in increased expression of CCL6 mRNA |
CTD |
PMID:21865292 PMID:29362864 |
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NCBI chr17:35,997,582...36,001,553
Ensembl chr17:35,996,440...36,001,553
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G |
R |
Ccl17 |
C-C motif chemokine ligand 17 |
increases expression |
ISO |
Tacrolimus results in increased expression of CCL17 mRNA |
CTD |
PMID:29362864 |
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NCBI chr19:10,202,317...10,203,768
Ensembl chr19:10,202,128...10,203,819
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G |
M |
Ccl17 |
chemokine (C-C motif) ligand 17 |
increases expression |
EXP |
Tacrolimus results in increased expression of CCL17 mRNA |
CTD |
PMID:29362864 |
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NCBI chr 8:95,535,996...95,538,666
Ensembl chr 8:95,537,081...95,538,664
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G |
H |
CCL17 |
C-C motif chemokine ligand 17 |
increases expression |
ISO |
Tacrolimus results in increased expression of CCL17 mRNA |
CTD |
PMID:29362864 |
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NCBI chr16:57,396,093...57,416,063
Ensembl chr16:57,404,767...57,416,063
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G |
R |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions increases expression |
EXP ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA] 7-oxozeanol inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; 7-oxozeanol inhibits the reaction [Tacrolimus results in increased expression of CCL2 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tacrolimus results in increased expression of CCL2 protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; parthenolide inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; pyrazolanthrone inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; pyrazolanthrone inhibits the reaction [Tacrolimus results in increased expression of CCL2 protein]; salubrinal inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; sulforaphane inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA] |
CTD |
PMID:12472797 PMID:23958496 PMID:29362864 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
M |
Ccl2 |
chemokine (C-C motif) ligand 2 |
multiple interactions increases expression |
EXP ISO |
7-oxozeanol inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; 7-oxozeanol inhibits the reaction [Tacrolimus results in increased expression of CCL2 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tacrolimus results in increased expression of CCL2 protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; parthenolide inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; pyrazolanthrone inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; pyrazolanthrone inhibits the reaction [Tacrolimus results in increased expression of CCL2 protein]; salubrinal inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; sulforaphane inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA] pyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA] |
CTD |
PMID:12472797 PMID:23958496 PMID:29362864 |
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NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
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G |
H |
CCL2 |
C-C motif chemokine ligand 2 |
multiple interactions increases expression |
ISO |
7-oxozeanol inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; 7-oxozeanol inhibits the reaction [Tacrolimus results in increased expression of CCL2 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tacrolimus results in increased expression of CCL2 protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; parthenolide inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; pyrazolanthrone inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; pyrazolanthrone inhibits the reaction [Tacrolimus results in increased expression of CCL2 protein]; salubrinal inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; sulforaphane inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA] pyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA] |
CTD |
PMID:12472797 PMID:23958496 PMID:29362864 |
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NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
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G |
R |
Ccl20 |
C-C motif chemokine ligand 20 |
increases expression |
ISO |
Tacrolimus results in increased expression of CCL20 mRNA |
CTD |
PMID:23958496 |
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NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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G |
M |
Ccl20 |
chemokine (C-C motif) ligand 20 |
increases expression |
EXP |
Tacrolimus results in increased expression of CCL20 mRNA |
CTD |
PMID:23958496 |
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NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888
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G |
H |
CCL20 |
C-C motif chemokine ligand 20 |
increases expression |
ISO |
Tacrolimus results in increased expression of CCL20 mRNA |
CTD |
PMID:23958496 |
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NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564
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G |
R |
Ccl5 |
C-C motif chemokine ligand 5 |
decreases expression increases expression multiple interactions |
ISO |
Tacrolimus results in decreased expression of CCL5 mRNA Tacrolimus results in increased expression of CCL5 mRNA 7-oxozeanol inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; parthenolide inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; pyrazolanthrone inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; salubrinal inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; sulforaphane inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA] |
CTD |
PMID:15948978 PMID:23958496 PMID:25270620 |
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NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
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G |
M |
Ccl5 |
chemokine (C-C motif) ligand 5 |
decreases expression increases expression multiple interactions |
ISO EXP |
Tacrolimus results in decreased expression of CCL5 mRNA Tacrolimus results in increased expression of CCL5 mRNA 7-oxozeanol inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; parthenolide inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; pyrazolanthrone inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; salubrinal inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; sulforaphane inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA] |
CTD |
PMID:15948978 PMID:23958496 PMID:25270620 |
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NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
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G |
H |
CCL5 |
C-C motif chemokine ligand 5 |
decreases expression increases expression multiple interactions |
EXP ISO |
Tacrolimus results in decreased expression of CCL5 mRNA Tacrolimus results in increased expression of CCL5 mRNA 7-oxozeanol inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; parthenolide inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; pyrazolanthrone inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; salubrinal inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; sulforaphane inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA] |
CTD |
PMID:15948978 PMID:23958496 PMID:25270620 |
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NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
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G |
M |
Ccl6 |
chemokine (C-C motif) ligand 6 |
increases expression |
EXP ISO |
Tacrolimus results in increased expression of CCL6 mRNA |
CTD |
PMID:21865292 PMID:29362864 |
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NCBI chr11:83,478,712...83,483,913
Ensembl chr11:83,478,708...83,483,913
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G |
R |
Ccl7 |
C-C motif chemokine ligand 7 |
increases expression |
ISO |
Tacrolimus results in increased expression of CCL7 mRNA |
CTD |
PMID:23958496 PMID:29362864 |
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NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
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G |
M |
Ccl7 |
chemokine (C-C motif) ligand 7 |
increases expression |
EXP |
Tacrolimus results in increased expression of CCL7 mRNA |
CTD |
PMID:23958496 PMID:29362864 |
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NCBI chr11:81,936,538...81,938,351
Ensembl chr11:81,936,538...81,938,351
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G |
H |
CCL7 |
C-C motif chemokine ligand 7 |
increases expression |
ISO |
Tacrolimus results in increased expression of CCL7 mRNA |
CTD |
PMID:23958496 PMID:29362864 |
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NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242
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G |
M |
Ccl8 |
chemokine (C-C motif) ligand 8 |
increases expression |
EXP |
Tacrolimus results in increased expression of CCL8 mRNA |
CTD |
PMID:29362864 |
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NCBI chr11:82,006,011...82,007,625
Ensembl chr11:82,006,011...82,007,625
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G |
R |
Ccl9 |
C-C motif chemokine ligand 9 |
increases expression |
EXP ISO |
Tacrolimus results in increased expression of CCL6 mRNA |
CTD |
PMID:21865292 PMID:29362864 |
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NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
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G |
R |
Ccn2 |
cellular communication network factor 2 |
multiple interactions |
EXP |
Tacrolimus inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA]; Tacrolimus inhibits the reaction [Paraquat results in increased secretion of CCN2 protein] |
CTD |
PMID:33000210 |
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NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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G |
M |
Ccn2 |
cellular communication network factor 2 |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA]; Tacrolimus inhibits the reaction [Paraquat results in increased secretion of CCN2 protein] |
CTD |
PMID:33000210 |
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NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581
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G |
H |
CCN2 |
cellular communication network factor 2 |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA]; Tacrolimus inhibits the reaction [Paraquat results in increased secretion of CCN2 protein] |
CTD |
PMID:33000210 |
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NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372
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G |
R |
Ccna2 |
cyclin A2 |
increases expression |
ISO |
Tacrolimus results in increased expression of CCNA2 mRNA |
CTD |
PMID:29362864 |
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NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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G |
M |
Ccna2 |
cyclin A2 |
increases expression |
EXP |
Tacrolimus results in increased expression of CCNA2 mRNA |
CTD |
PMID:29362864 |
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NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299
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G |
H |
CCNA2 |
cyclin A2 |
increases expression |
ISO |
Tacrolimus results in increased expression of CCNA2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883
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G |
R |
Ccnb2 |
cyclin B2 |
decreases expression increases expression |
ISO |
Tacrolimus results in decreased expression of CCNB2 mRNA Tacrolimus results in increased expression of CCNB2 mRNA |
CTD |
PMID:16574167 PMID:29362864 |
|
NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
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G |
M |
Ccnb2 |
cyclin B2 |
decreases expression increases expression |
ISO EXP |
Tacrolimus results in decreased expression of CCNB2 mRNA Tacrolimus results in increased expression of CCNB2 mRNA |
CTD |
PMID:16574167 PMID:29362864 |
|
NCBI chr 9:70,314,971...70,328,836
Ensembl chr 9:70,314,974...70,328,829
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G |
H |
CCNB2 |
cyclin B2 |
decreases expression increases expression |
EXP ISO |
Tacrolimus results in decreased expression of CCNB2 mRNA Tacrolimus results in increased expression of CCNB2 mRNA |
CTD |
PMID:16574167 PMID:29362864 |
|
NCBI chr15:59,105,146...59,125,045
Ensembl chr15:59,105,126...59,125,045
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G |
R |
Ccr2 |
C-C motif chemokine receptor 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of CCR2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
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G |
M |
Ccr2 |
chemokine (C-C motif) receptor 2 |
increases expression |
EXP |
Tacrolimus results in increased expression of CCR2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594
|
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G |
H |
CCR2 |
C-C motif chemokine receptor 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of CCR2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940
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G |
R |
Ccr3 |
C-C motif chemokine receptor 3 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of CCR3 mRNA |
CTD |
PMID:15948978 |
|
NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990
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G |
M |
Ccr3 |
chemokine (C-C motif) receptor 3 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of CCR3 mRNA |
CTD |
PMID:15948978 |
|
NCBI chr 9:123,817,799...123,831,729
Ensembl chr 9:123,822,009...123,831,726
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G |
H |
CCR3 |
C-C motif chemokine receptor 3 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of CCR3 mRNA |
CTD |
PMID:15948978 |
|
NCBI chr 3:46,210,696...46,266,706
Ensembl chr 3:46,130,890...46,266,706
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G |
R |
Ccrl2 |
C-C motif chemokine receptor like 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of CCRL2 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr 8:111,034,279...111,036,914
Ensembl chr 8:111,034,279...111,036,664
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G |
M |
Ccrl2 |
chemokine (C-C motif) receptor-like 2 |
increases expression |
EXP |
Tacrolimus results in increased expression of CCRL2 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr 9:110,883,902...110,886,586
Ensembl chr 9:110,883,554...110,886,587
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G |
H |
CCRL2 |
C-C motif chemokine receptor like 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of CCRL2 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr 3:46,407,259...46,409,523
Ensembl chr 3:46,407,166...46,412,997
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G |
R |
Cd2 |
Cd2 molecule |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [CD2 protein results in increased expression of IL2 protein] |
CTD |
PMID:1705513 |
|
NCBI chr 2:188,710,895...188,724,044
Ensembl chr 2:188,710,900...188,724,026
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G |
M |
Cd2 |
CD2 antigen |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [CD2 protein results in increased expression of IL2 protein] |
CTD |
PMID:1705513 |
|
NCBI chr 3:101,183,224...101,195,255
Ensembl chr 3:101,183,215...101,195,255
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G |
H |
CD2 |
CD2 molecule |
multiple interactions |
EXP |
Tacrolimus inhibits the reaction [CD2 protein results in increased expression of IL2 protein] |
CTD |
PMID:1705513 |
|
NCBI chr 1:116,754,430...116,769,229
Ensembl chr 1:116,754,430...116,769,229
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G |
R |
Cd44 |
CD44 molecule (Indian blood group) |
increases expression |
EXP |
Tacrolimus results in increased expression of CD44 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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G |
M |
Cd44 |
CD44 antigen |
increases expression |
ISO |
Tacrolimus results in increased expression of CD44 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
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G |
H |
CD44 |
CD44 molecule (Indian blood group) |
increases expression |
ISO |
Tacrolimus results in increased expression of CD44 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402
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G |
R |
Cd68 |
Cd68 molecule |
increases expression |
EXP |
Tacrolimus results in increased expression of CD68 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
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G |
M |
Cd68 |
CD68 antigen |
increases expression |
ISO |
Tacrolimus results in increased expression of CD68 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr11:69,555,039...69,556,996
Ensembl chr11:69,555,039...69,556,979
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G |
H |
CD68 |
CD68 molecule |
increases expression |
ISO |
Tacrolimus results in increased expression of CD68 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr17:7,579,638...7,582,111
Ensembl chr17:7,579,491...7,582,111
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G |
R |
Cd74 |
CD74 molecule |
increases expression |
ISO |
Tacrolimus results in increased expression of CD74 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
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G |
M |
Cd74 |
CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) |
increases expression |
EXP |
Tacrolimus results in increased expression of CD74 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr18:60,936,921...60,945,724
Ensembl chr18:60,936,920...60,945,724
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G |
H |
CD74 |
CD74 molecule |
increases expression |
ISO |
Tacrolimus results in increased expression of CD74 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr 5:150,401,639...150,412,910
Ensembl chr 5:150,401,637...150,412,969
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G |
R |
Cd80 |
Cd80 molecule |
decreases expression |
ISO |
Tacrolimus results in decreased expression of CD80 protein |
CTD |
PMID:15241357 |
|
NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
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G |
M |
Cd80 |
CD80 antigen |
decreases expression |
ISO |
Tacrolimus results in decreased expression of CD80 protein |
CTD |
PMID:15241357 |
|
NCBI chr16:38,277,793...38,316,682
Ensembl chr16:38,275,923...38,316,697
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G |
H |
CD80 |
CD80 molecule |
decreases expression |
EXP |
Tacrolimus results in decreased expression of CD80 protein |
CTD |
PMID:15241357 |
|
NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614
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G |
R |
Cd83 |
CD83 molecule |
increases expression |
ISO |
Tacrolimus results in increased expression of CD83 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
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G |
M |
Cd83 |
CD83 antigen |
increases expression |
EXP |
Tacrolimus results in increased expression of CD83 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr13:43,938,588...43,956,609
Ensembl chr13:43,938,251...43,956,608
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G |
H |
CD83 |
CD83 molecule |
increases expression |
ISO |
Tacrolimus results in increased expression of CD83 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 6:14,117,256...14,136,918
Ensembl chr 6:14,117,256...14,136,918
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G |
R |
Cd86 |
CD86 molecule |
decreases expression |
ISO |
Tacrolimus results in decreased expression of CD86 protein |
CTD |
PMID:15241357 |
|
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
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G |
M |
Cd86 |
CD86 antigen |
decreases expression |
ISO |
Tacrolimus results in decreased expression of CD86 protein |
CTD |
PMID:15241357 |
|
NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443
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G |
H |
CD86 |
CD86 molecule |
decreases expression |
EXP |
Tacrolimus results in decreased expression of CD86 protein |
CTD |
PMID:15241357 |
|
NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
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G |
R |
Cdca3 |
cell division cycle associated 3 |
increases expression |
ISO |
Tacrolimus results in increased expression of CDCA3 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799
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G |
M |
Cdca3 |
cell division cycle associated 3 |
increases expression |
EXP |
Tacrolimus results in increased expression of CDCA3 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 6:124,806,533...124,810,664
Ensembl chr 6:124,806,510...124,810,664
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G |
H |
CDCA3 |
cell division cycle associated 3 |
increases expression |
ISO |
Tacrolimus results in increased expression of CDCA3 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr12:6,844,798...6,851,286
Ensembl chr12:6,844,793...6,851,292
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G |
R |
Cdca5 |
cell division cycle associated 5 |
increases expression |
ISO |
Tacrolimus results in increased expression of CDCA5 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023
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G |
M |
Cdca5 |
cell division cycle associated 5 |
increases expression |
EXP |
Tacrolimus results in increased expression of CDCA5 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr19:6,135,127...6,141,803
Ensembl chr19:6,135,013...6,141,807
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G |
H |
CDCA5 |
cell division cycle associated 5 |
increases expression |
ISO |
Tacrolimus results in increased expression of CDCA5 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr11:65,061,093...65,084,040
Ensembl chr11:65,066,300...65,084,164
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G |
R |
Cdca8 |
cell division cycle associated 8 |
increases expression |
ISO |
Tacrolimus results in increased expression of CDCA8 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629
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G |
M |
Cdca8 |
cell division cycle associated 8 |
increases expression |
EXP |
Tacrolimus results in increased expression of CDCA8 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 4:124,812,258...124,830,710
Ensembl chr 4:124,812,258...124,833,104
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G |
H |
CDCA8 |
cell division cycle associated 8 |
increases expression |
ISO |
Tacrolimus results in increased expression of CDCA8 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 1:37,692,516...37,709,719
Ensembl chr 1:37,692,481...37,709,719
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G |
R |
Cdh1 |
cadherin 1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of CDH1 protein |
CTD |
PMID:22416070 |
|
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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G |
M |
Cdh1 |
cadherin 1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of CDH1 protein |
CTD |
PMID:22416070 |
|
NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
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G |
H |
CDH1 |
cadherin 1 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of CDH1 protein |
CTD |
PMID:22416070 |
|
NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
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G |
R |
Cdh11 |
cadherin 11 |
increases expression |
ISO |
Tacrolimus results in increased expression of CDH11 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272
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G |
M |
Cdh11 |
cadherin 11 |
increases expression |
EXP |
Tacrolimus results in increased expression of CDH11 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 8:103,358,727...103,512,125
Ensembl chr 8:103,358,727...103,512,274
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G |
H |
CDH11 |
cadherin 11 |
increases expression |
ISO |
Tacrolimus results in increased expression of CDH11 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr16:64,943,753...65,123,744
Ensembl chr16:64,943,753...65,126,112
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G |
R |
Cdh16 |
cadherin 16 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of CDH16 mRNA |
CTD |
PMID:22416070 |
|
NCBI chr19:360,824...371,008
Ensembl chr19:360,824...371,007
|
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G |
M |
Cdh16 |
cadherin 16 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of CDH16 mRNA |
CTD |
PMID:22416070 |
|
NCBI chr 8:105,328,547...105,351,028
Ensembl chr 8:105,328,543...105,351,028
|
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G |
H |
CDH16 |
cadherin 16 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of CDH16 mRNA |
CTD |
PMID:22416070 |
|
NCBI chr16:66,908,122...66,918,885
Ensembl chr16:66,908,122...66,918,917
|
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G |
R |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
increases expression |
EXP |
Tacrolimus results in increased expression of CDKN1B mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
M |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
increases expression |
ISO |
Tacrolimus results in increased expression of CDKN1B mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
|
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G |
H |
CDKN1B |
cyclin dependent kinase inhibitor 1B |
increases expression |
ISO |
Tacrolimus results in increased expression of CDKN1B mRNA |
CTD |
PMID:21865292 |
|
NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
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G |
R |
Cebpa |
CCAAT/enhancer binding protein alpha |
increases expression |
ISO |
Tacrolimus results in increased expression of CEBPA mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
M |
Cebpa |
CCAAT/enhancer binding protein (C/EBP), alpha |
increases expression |
EXP |
Tacrolimus results in increased expression of CEBPA mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353
|
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G |
H |
CEBPA |
CCAAT enhancer binding protein alpha |
increases expression |
ISO |
Tacrolimus results in increased expression of CEBPA mRNA |
CTD |
PMID:29362864 |
|
NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534
|
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G |
R |
Cenpw |
centromere protein W |
increases expression |
ISO |
Tacrolimus results in increased expression of CENPW mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 1:27,525,324...27,530,464
Ensembl chr 1:27,525,324...27,530,464
|
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G |
M |
Cenpw |
centromere protein W |
increases expression |
EXP |
Tacrolimus results in increased expression of CENPW mRNA |
CTD |
PMID:29362864 |
|
NCBI chr10:30,072,005...30,076,599
Ensembl chr10:30,070,565...30,076,556
|
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G |
H |
CENPW |
centromere protein W |
increases expression |
ISO |
Tacrolimus results in increased expression of CENPW mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 6:126,340,115...126,483,320
Ensembl chr 6:126,340,115...126,348,875
|
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G |
R |
Cfi |
complement factor I |
increases expression |
EXP |
Tacrolimus results in increased expression of CFI mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 2:218,389,079...218,430,565
Ensembl chr 2:218,387,990...218,430,561
|
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G |
M |
Cfi |
complement component factor i |
increases expression |
ISO |
Tacrolimus results in increased expression of CFI mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 3:129,630,376...129,668,981
Ensembl chr 3:129,629,533...129,668,981
|
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G |
H |
CFI |
complement factor I |
increases expression |
ISO |
Tacrolimus results in increased expression of CFI mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 4:109,730,982...109,801,999
Ensembl chr 4:109,731,008...109,802,150
|
|
G |
R |
Ckap2 |
cytoskeleton associated protein 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of CKAP2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
|
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G |
M |
Ckap2 |
cytoskeleton associated protein 2 |
increases expression |
EXP |
Tacrolimus results in increased expression of CKAP2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 8:22,658,168...22,675,835
Ensembl chr 8:22,658,176...22,675,835
|
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G |
H |
CKAP2 |
cytoskeleton associated protein 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of CKAP2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr13:52,455,478...52,476,627
Ensembl chr13:52,455,429...52,476,628
|
|
G |
R |
Ckap4 |
cytoskeleton-associated protein 4 |
increases expression |
EXP |
Tacrolimus results in increased expression of CKAP4 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 7:19,230,814...19,238,914
Ensembl chr 7:19,230,203...19,238,914
|
|
G |
M |
Ckap4 |
cytoskeleton-associated protein 4 |
increases expression |
ISO |
Tacrolimus results in increased expression of CKAP4 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr10:84,362,169...84,369,752
Ensembl chr10:84,362,169...84,369,926
|
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G |
H |
CKAP4 |
cytoskeleton associated protein 4 |
increases expression |
ISO |
Tacrolimus results in increased expression of CKAP4 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr12:106,237,881...106,248,020
Ensembl chr12:106,237,881...106,304,279
|
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G |
R |
Cldn1 |
claudin 1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of CLDN1 mRNA |
CTD |
PMID:22416070 |
|
NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
|
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G |
M |
Cldn1 |
claudin 1 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of CLDN1 mRNA |
CTD |
PMID:22416070 |
|
NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591
|
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G |
H |
CLDN1 |
claudin 1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of CLDN1 mRNA |
CTD |
PMID:22416070 |
|
NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446
|
|
G |
R |
Cldn4 |
claudin 4 |
increases expression |
EXP |
Tacrolimus results in increased expression of CLDN4 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
|
|
G |
M |
Cldn4 |
claudin 4 |
increases expression |
ISO |
Tacrolimus results in increased expression of CLDN4 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 5:134,973,977...134,975,788
Ensembl chr 5:134,973,973...134,975,788
|
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G |
H |
CLDN4 |
claudin 4 |
increases expression |
ISO |
Tacrolimus results in increased expression of CLDN4 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 7:73,830,996...73,832,690
Ensembl chr 7:73,799,542...73,832,690
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G |
R |
Cldn7 |
claudin 7 |
increases expression |
EXP |
Tacrolimus results in increased expression of CLDN7 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr10:54,689,684...54,692,177
Ensembl chr10:54,689,987...54,692,171
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G |
M |
Cldn7 |
claudin 7 |
increases expression |
ISO |
Tacrolimus results in increased expression of CLDN7 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr11:69,855,605...69,858,712
Ensembl chr11:69,855,605...69,858,711
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G |
H |
CLDN7 |
claudin 7 |
increases expression |
ISO |
Tacrolimus results in increased expression of CLDN7 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr17:7,259,903...7,263,213
Ensembl chr17:7,259,903...7,263,983
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G |
R |
Clec7a |
C-type lectin domain containing 7A |
increases expression |
ISO |
Tacrolimus results in increased expression of CLEC7A mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897
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G |
M |
Clec7a |
C-type lectin domain family 7, member a |
increases expression |
EXP |
Tacrolimus results in increased expression of CLEC7A mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 6:129,438,554...129,449,748
Ensembl chr 6:129,438,554...129,449,742
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G |
H |
CLEC7A |
C-type lectin domain containing 7A |
increases expression |
ISO |
Tacrolimus results in increased expression of CLEC7A mRNA |
CTD |
PMID:29362864 |
|
NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258
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G |
R |
Clk3 |
CDC-like kinase 3 |
increases expression |
ISO |
Tacrolimus results in increased expression of CLK3 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 8:58,152,155...58,167,196
Ensembl chr 8:58,152,155...58,168,181
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G |
M |
Clk3 |
CDC-like kinase 3 |
increases expression |
EXP |
Tacrolimus results in increased expression of CLK3 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 9:57,657,904...57,673,518
Ensembl chr 9:57,657,907...57,673,143
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G |
H |
CLK3 |
CDC like kinase 3 |
increases expression |
ISO |
Tacrolimus results in increased expression of CLK3 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr15:74,608,372...74,630,201
Ensembl chr15:74,598,500...74,645,414
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G |
R |
Clu |
clusterin |
increases expression |
EXP |
Tacrolimus results in increased expression of CLU mRNA |
CTD |
PMID:21865292 |
|
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
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G |
M |
Clu |
clusterin |
increases expression |
ISO |
Tacrolimus results in increased expression of CLU mRNA |
CTD |
PMID:21865292 |
|
NCBI chr14:66,205,932...66,218,997
Ensembl chr14:66,205,932...66,218,996
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G |
H |
CLU |
clusterin |
increases expression |
ISO |
Tacrolimus results in increased expression of CLU mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700
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G |
R |
Coch |
cochlin |
increases expression |
ISO |
Tacrolimus results in increased expression of COCH mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 6:69,031,139...69,045,124
Ensembl chr 6:69,031,167...69,045,109
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G |
M |
Coch |
cochlin |
increases expression |
EXP |
Tacrolimus results in increased expression of COCH mRNA |
CTD |
PMID:25270620 |
|
NCBI chr12:51,640,067...51,652,556
Ensembl chr12:51,640,124...51,652,554
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G |
H |
COCH |
cochlin |
increases expression |
ISO |
Tacrolimus results in increased expression of COCH mRNA |
CTD |
PMID:25270620 |
|
NCBI chr14:30,874,559...30,895,615
Ensembl chr14:30,874,514...30,895,065
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G |
R |
Col1a1 |
collagen type I alpha 1 chain |
increases expression |
ISO |
Tacrolimus results in increased expression of COL1A1 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
M |
Col1a1 |
collagen, type I, alpha 1 |
increases expression |
ISO EXP |
Tacrolimus results in increased expression of COL1A1 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
|
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G |
H |
COL1A1 |
collagen type I alpha 1 chain |
increases expression |
ISO EXP |
Tacrolimus results in increased expression of COL1A1 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
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G |
R |
Col1a2 |
collagen type I alpha 2 chain |
increases expression |
ISO |
Tacrolimus results in increased expression of COL1A2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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G |
M |
Col1a2 |
collagen, type I, alpha 2 |
increases expression |
EXP |
Tacrolimus results in increased expression of COL1A2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 6:4,505,618...4,541,543
Ensembl chr 6:4,504,814...4,541,544
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G |
H |
COL1A2 |
collagen type I alpha 2 chain |
increases expression |
ISO |
Tacrolimus results in increased expression of COL1A2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227
|
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G |
R |
Col3a1 |
collagen type III alpha 1 chain |
increases expression |
ISO |
Tacrolimus results in increased expression of COL3A1 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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G |
M |
Col3a1 |
collagen, type III, alpha 1 |
increases expression |
EXP |
Tacrolimus results in increased expression of COL3A1 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866
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G |
H |
COL3A1 |
collagen type III alpha 1 chain |
increases expression |
ISO |
Tacrolimus results in increased expression of COL3A1 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746
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G |
R |
Cops8 |
COP9 signalosome subunit 8 |
increases expression |
ISO |
Tacrolimus results in increased expression of COPS8 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 9:91,207,427...91,217,258
Ensembl chr 9:91,207,395...91,217,258
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G |
M |
Cops8 |
COP9 signalosome subunit 8 |
increases expression |
EXP |
Tacrolimus results in increased expression of COPS8 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 1:90,531,147...90,541,063
Ensembl chr 1:90,530,703...90,541,063
|
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G |
H |
COPS8 |
COP9 signalosome subunit 8 |
increases expression |
ISO |
Tacrolimus results in increased expression of COPS8 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 2:237,085,889...237,100,474
Ensembl chr 2:237,085,882...237,100,474
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G |
R |
Cp |
ceruloplasmin |
increases expression |
EXP |
Tacrolimus results in increased expression of CP mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
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G |
M |
Cp |
ceruloplasmin |
increases expression |
ISO |
Tacrolimus results in increased expression of CP mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 3:20,011,097...20,063,914
Ensembl chr 3:20,011,218...20,063,309
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G |
H |
CP |
ceruloplasmin |
increases expression |
ISO |
Tacrolimus results in increased expression of CP mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829
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G |
R |
Creb3l3 |
cAMP responsive element binding protein 3-like 3 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of CREB3L3 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048
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G |
M |
Creb3l3 |
cAMP responsive element binding protein 3-like 3 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of CREB3L3 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr10:80,920,163...80,934,706
Ensembl chr10:80,920,158...80,934,708
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G |
H |
CREB3L3 |
cAMP responsive element binding protein 3 like 3 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of CREB3L3 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr19:4,153,631...4,173,054
Ensembl chr19:4,153,631...4,173,054
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G |
R |
Creld2 |
cysteine-rich with EGF-like domains 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of CRELD2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:119,909,633...119,916,543
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G |
M |
Creld2 |
cysteine-rich with EGF-like domains 2 |
increases expression |
EXP |
Tacrolimus results in increased expression of CRELD2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr15:88,703,849...88,710,884
Ensembl chr15:88,703,849...88,710,886
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G |
H |
CRELD2 |
cysteine rich with EGF like domains 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of CRELD2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr22:49,918,634...49,927,537
Ensembl chr22:49,918,167...49,927,540
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G |
R |
Csf1 |
colony stimulating factor 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of CSF1 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
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G |
M |
Csf1 |
colony stimulating factor 1 (macrophage) |
increases expression |
EXP |
Tacrolimus results in increased expression of CSF1 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785
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G |
H |
CSF1 |
colony stimulating factor 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of CSF1 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr 1:109,910,506...109,930,992
Ensembl chr 1:109,910,242...109,930,992
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G |
R |
Csf2 |
colony stimulating factor 2 |
decreases expression increases expression multiple interactions |
ISO |
Tacrolimus results in decreased expression of CSF2 protein Tacrolimus results in increased expression of CSF2 mRNA Sirolimus inhibits the reaction [Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CSF2 protein]]; Tacrolimus inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF2 protein] |
CTD |
PMID:1376361 PMID:11407316 PMID:23958496 |
|
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
|
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G |
M |
Csf2 |
colony stimulating factor 2 (granulocyte-macrophage) |
decreases expression increases expression multiple interactions |
ISO EXP |
Tacrolimus results in decreased expression of CSF2 protein Tacrolimus results in increased expression of CSF2 mRNA Sirolimus inhibits the reaction [Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CSF2 protein]]; Tacrolimus inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF2 protein] |
CTD |
PMID:1376361 PMID:11407316 PMID:23958496 |
|
NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493
|
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G |
H |
CSF2 |
colony stimulating factor 2 |
decreases expression increases expression multiple interactions |
EXP ISO |
Tacrolimus results in decreased expression of CSF2 protein Tacrolimus results in increased expression of CSF2 mRNA Sirolimus inhibits the reaction [Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CSF2 protein]]; Tacrolimus inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF2 protein] |
CTD |
PMID:1376361 PMID:11407316 PMID:23958496 |
|
NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
|
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G |
R |
Csf2rb |
colony stimulating factor 2 receptor subunit beta |
increases expression |
ISO |
Tacrolimus results in increased expression of CSF2RB2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157
|
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G |
H |
CSF2RB |
colony stimulating factor 2 receptor subunit beta |
increases expression |
ISO |
Tacrolimus results in increased expression of CSF2RB2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr22:36,913,628...36,940,439
Ensembl chr22:36,913,628...36,940,439
|
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G |
M |
Csf2rb2 |
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) |
increases expression |
EXP |
Tacrolimus results in increased expression of CSF2RB2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr15:78,166,707...78,189,921
Ensembl chr15:78,166,707...78,189,921
|
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G |
R |
Ctsl |
cathepsin L |
multiple interactions increases expression |
ISO EXP |
Tacrolimus inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CTSL protein] Tacrolimus results in increased expression of CTSL mRNA |
CTD |
PMID:18172886 PMID:21865292 PMID:25270620 |
|
NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
|
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G |
M |
Ctsl |
cathepsin L |
multiple interactions increases expression |
EXP ISO |
Tacrolimus inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CTSL protein] Tacrolimus results in increased expression of CTSL mRNA |
CTD |
PMID:18172886 PMID:21865292 PMID:25270620 |
|
NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704
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G |
H |
CTSL |
cathepsin L |
multiple interactions increases expression |
ISO |
Tacrolimus inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CTSL protein] Tacrolimus results in increased expression of CTSL mRNA |
CTD |
PMID:18172886 PMID:21865292 PMID:25270620 |
|
NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469
|
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G |
R |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
increases expression |
EXP ISO |
Tacrolimus results in increased expression of CXCL10 mRNA |
CTD |
PMID:21865292 PMID:23958496 PMID:25270620 |
|
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
M |
Cxcl10 |
chemokine (C-X-C motif) ligand 10 |
increases expression |
ISO EXP |
Tacrolimus results in increased expression of CXCL10 mRNA |
CTD |
PMID:21865292 PMID:23958496 PMID:25270620 |
|
NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
|
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G |
H |
CXCL10 |
C-X-C motif chemokine ligand 10 |
increases expression |
ISO |
Tacrolimus results in increased expression of CXCL10 mRNA |
CTD |
PMID:21865292 PMID:23958496 PMID:25270620 |
|
NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
|
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G |
R |
Cxcl11 |
C-X-C motif chemokine ligand 11 |
increases expression |
ISO |
Tacrolimus results in increased expression of CXCL11 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271
|
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G |
M |
Cxcl11 |
chemokine (C-X-C motif) ligand 11 |
increases expression |
EXP |
Tacrolimus results in increased expression of CXCL11 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr 5:92,507,403...92,511,155
Ensembl chr 5:92,507,403...92,513,344
|
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G |
H |
CXCL11 |
C-X-C motif chemokine ligand 11 |
increases expression |
ISO |
Tacrolimus results in increased expression of CXCL11 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr 4:76,033,682...76,036,070
Ensembl chr 4:76,033,682...76,041,415
|
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G |
M |
Cxcl15 |
chemokine (C-X-C motif) ligand 15 |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [cinnamaldehyde results in increased expression of CXCL8 mRNA]; Tacrolimus inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL8 mRNA] |
CTD |
PMID:20090409 |
|
NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
|
|
G |
H |
CXCL8 |
C-X-C motif chemokine ligand 8 |
multiple interactions |
EXP |
Tacrolimus inhibits the reaction [cinnamaldehyde results in increased expression of CXCL8 mRNA]; Tacrolimus inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL8 mRNA] |
CTD |
PMID:20090409 |
|
NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
|
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G |
R |
Cyba |
cytochrome b-245 alpha chain |
multiple interactions increases expression |
ISO |
Ramipril inhibits the reaction [Tacrolimus results in increased expression of CYBA mRNA] |
CTD |
PMID:12352326 |
|
NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
|
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G |
M |
Cyba |
cytochrome b-245, alpha polypeptide |
multiple interactions increases expression |
ISO |
Ramipril inhibits the reaction [Tacrolimus results in increased expression of CYBA mRNA] |
CTD |
PMID:12352326 |
|
NCBI chr 8:123,151,510...123,159,679
Ensembl chr 8:123,151,515...123,159,669
|
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G |
H |
CYBA |
cytochrome b-245 alpha chain |
multiple interactions increases expression |
EXP |
Ramipril inhibits the reaction [Tacrolimus results in increased expression of CYBA mRNA] |
CTD |
PMID:12352326 |
|
NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083
|
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G |
R |
Cyp27b1 |
cytochrome P450, family 27, subfamily b, polypeptide 1 |
increases expression |
EXP |
Tacrolimus results in increased expression of CYP27B1 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
|
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G |
M |
Cyp27b1 |
cytochrome P450, family 27, subfamily b, polypeptide 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of CYP27B1 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr10:126,884,115...126,891,897
Ensembl chr10:126,884,119...126,888,875
|
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G |
H |
CYP27B1 |
cytochrome P450 family 27 subfamily B member 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of CYP27B1 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr12:57,762,334...57,767,078
Ensembl chr12:57,762,334...57,768,986
|
|
G |
H |
CYP2C19 |
cytochrome P450 family 2 subfamily C member 19 |
multiple interactions |
EXP |
CYP2C19 affects the reaction [Lansoprazole affects the susceptibility to Tacrolimus]; CYP2C19 affects the susceptibility to [Tacrolimus co-treated with Lansoprazole]; CYP2C19 affects the susceptibility to [Tacrolimus co-treated with Rabeprazole]; CYP2C19 gene mutant form affects the susceptibility to [Lansoprazole co-treated with Tacrolimus] |
CTD |
PMID:15010519 PMID:15285851 PMID:17377957 |
|
NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
|
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G |
M |
Cyp2c38 |
cytochrome P450, family 2, subfamily c, polypeptide 38 |
multiple interactions |
ISO |
CYP2C19 affects the reaction [Lansoprazole affects the susceptibility to Tacrolimus]; CYP2C19 affects the susceptibility to [Tacrolimus co-treated with Lansoprazole]; CYP2C19 affects the susceptibility to [Tacrolimus co-treated with Rabeprazole]; CYP2C19 gene mutant form affects the susceptibility to [Lansoprazole co-treated with Tacrolimus] |
CTD |
PMID:15010519 PMID:15285851 PMID:17377957 |
|
NCBI chr19:39,378,000...39,451,547
Ensembl chr19:39,378,000...39,451,519
|
|
G |
R |
Cyp2c6v1 |
cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 |
multiple interactions |
ISO |
CYP2C19 affects the reaction [Lansoprazole affects the susceptibility to Tacrolimus]; CYP2C19 affects the susceptibility to [Tacrolimus co-treated with Lansoprazole]; CYP2C19 affects the susceptibility to [Tacrolimus co-treated with Rabeprazole]; CYP2C19 gene mutant form affects the susceptibility to [Lansoprazole co-treated with Tacrolimus] |
CTD |
PMID:15010519 PMID:15285851 PMID:17377957 |
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NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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Cyp3a11 |
cytochrome P450, family 3, subfamily a, polypeptide 11 |
decreases methylation affects metabolic processing affects response to substance multiple interactions |
ISO |
CYP3A5 protein results in decreased methylation of Tacrolimus CYP3A5 gene polymorphism affects the metabolism of Tacrolimus; CYP3A5 gene SNP affects the metabolism of Tacrolimus; CYP3A5 protein affects the metabolism of Tacrolimus; CYP3A5 protein polymorphism affects the metabolism of Tacrolimus CYP3A5 gene affects the susceptibility to Tacrolimus CYP3A5 affects the susceptibility to [Tacrolimus co-treated with Lansoprazole]; CYP3A5 affects the susceptibility to [Tacrolimus co-treated with Rabeprazole]; CYP3A5 gene polymorphism affects the reaction [Ketoconazole results in decreased metabolism of Tacrolimus] |
CTD |
PMID:15502717 PMID:15723604 PMID:15729180 PMID:15808586 PMID:15919447 PMID:15951320 PMID:15964336 PMID:17377957 PMID:19384264 More...
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NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774
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Cyp3a13 |
cytochrome P450, family 3, subfamily a, polypeptide 13 |
decreases methylation |
ISO |
CYP3A7 protein results in decreased methylation of Tacrolimus |
CTD |
PMID:15951320 |
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NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881
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Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
increases metabolic processing affects metabolic processing decreases methylation multiple interactions |
ISO |
CYP3A4 protein results in increased metabolism of Tacrolimus CYP3A4 protein affects the metabolism of Tacrolimus CYP3A4 protein results in decreased methylation of Tacrolimus Metronidazole inhibits the reaction [CYP3A4 protein results in increased metabolism of Tacrolimus] |
CTD |
PMID:15010519 PMID:15855244 PMID:15919446 PMID:15951320 PMID:15964336 |
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NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
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CYP3A4 |
cytochrome P450 family 3 subfamily A member 4 |
affects metabolic processing decreases methylation increases metabolic processing multiple interactions |
EXP |
CYP3A4 protein affects the metabolism of Tacrolimus CYP3A4 protein results in decreased methylation of Tacrolimus CYP3A4 protein results in increased metabolism of Tacrolimus Metronidazole inhibits the reaction [CYP3A4 protein results in increased metabolism of Tacrolimus] |
CTD |
PMID:15010519 PMID:15855244 PMID:15919446 PMID:15951320 PMID:15964336 |
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NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
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CYP3A5 |
cytochrome P450 family 3 subfamily A member 5 |
multiple interactions decreases methylation affects metabolic processing affects response to substance |
EXP |
CYP3A5 affects the susceptibility to [Tacrolimus co-treated with Lansoprazole]; CYP3A5 affects the susceptibility to [Tacrolimus co-treated with Rabeprazole]; CYP3A5 gene polymorphism affects the reaction [Ketoconazole results in decreased metabolism of Tacrolimus] CYP3A5 protein results in decreased methylation of Tacrolimus CYP3A5 gene polymorphism affects the metabolism of Tacrolimus; CYP3A5 gene SNP affects the metabolism of Tacrolimus; CYP3A5 protein affects the metabolism of Tacrolimus; CYP3A5 protein polymorphism affects the metabolism of Tacrolimus CYP3A5 gene affects the susceptibility to Tacrolimus |
CTD |
PMID:15502717 PMID:15723604 PMID:15729180 PMID:15808586 PMID:15919447 PMID:15951320 PMID:15964336 PMID:17377957 PMID:19384264 More...
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NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,998
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CYP3A51P |
cytochrome P450 family 3 subfamily A member 51, pseudogene |
affects metabolic processing |
EXP |
CYP3A51P gene SNP affects the metabolism of Tacrolimus |
CTD |
PMID:15729180 |
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NCBI chr 7:99,685,024...99,700,120
Ensembl chr 7:99,685,145...99,700,034
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CYP3A7 |
cytochrome P450 family 3 subfamily A member 7 |
decreases methylation |
EXP |
CYP3A7 protein results in decreased methylation of Tacrolimus |
CTD |
PMID:15951320 |
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NCBI chr 7:99,705,036...99,735,196
Ensembl chr 7:99,705,036...99,735,196
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Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
multiple interactions decreases methylation affects metabolic processing affects response to substance |
ISO |
CYP3A5 affects the susceptibility to [Tacrolimus co-treated with Lansoprazole]; CYP3A5 affects the susceptibility to [Tacrolimus co-treated with Rabeprazole]; CYP3A5 gene polymorphism affects the reaction [Ketoconazole results in decreased metabolism of Tacrolimus] CYP3A5 protein results in decreased methylation of Tacrolimus CYP3A5 gene polymorphism affects the metabolism of Tacrolimus; CYP3A5 gene SNP affects the metabolism of Tacrolimus; CYP3A5 protein affects the metabolism of Tacrolimus; CYP3A5 protein polymorphism affects the metabolism of Tacrolimus CYP3A5 gene affects the susceptibility to Tacrolimus |
CTD |
PMID:15502717 PMID:15723604 PMID:15729180 PMID:15808586 PMID:15919447 PMID:15951320 PMID:15964336 PMID:17377957 PMID:19384264 More...
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NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
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Dcn |
decorin |
increases expression |
ISO |
Tacrolimus results in increased expression of DCN mRNA |
CTD |
PMID:29362864 |
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NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
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Dcn |
decorin |
increases expression |
EXP |
Tacrolimus results in increased expression of DCN mRNA |
CTD |
PMID:29362864 |
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NCBI chr10:97,315,362...97,354,025
Ensembl chr10:97,315,471...97,354,005
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DCN |
decorin |
increases expression |
ISO |
Tacrolimus results in increased expression of DCN mRNA |
CTD |
PMID:29362864 |
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NCBI chr12:91,140,484...91,182,817
Ensembl chr12:91,140,484...91,183,217
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Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions increases expression |
ISO |
salubrinal promotes the reaction [Tacrolimus results in increased expression of DDIT3 protein] Tacrolimus results in increased expression of DDIT3 mRNA |
CTD |
PMID:23958496 PMID:25270620 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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M |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions increases expression |
EXP |
salubrinal promotes the reaction [Tacrolimus results in increased expression of DDIT3 protein] Tacrolimus results in increased expression of DDIT3 mRNA |
CTD |
PMID:23958496 PMID:25270620 |
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NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157 Ensembl chr10:127,126,643...127,132,157
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DDIT3 |
DNA damage inducible transcript 3 |
multiple interactions increases expression |
ISO |
salubrinal promotes the reaction [Tacrolimus results in increased expression of DDIT3 protein] Tacrolimus results in increased expression of DDIT3 mRNA |
CTD |
PMID:23958496 PMID:25270620 |
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NCBI chr12:57,516,588...57,521,698
Ensembl chr12:57,516,588...57,521,737
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Ddit4l |
DNA-damage-inducible transcript 4-like |
decreases expression |
EXP |
Tacrolimus results in decreased expression of DDIT4L mRNA |
CTD |
PMID:21865292 |
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NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375
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M |
Ddit4l |
DNA-damage-inducible transcript 4-like |
decreases expression |
ISO |
Tacrolimus results in decreased expression of DDIT4L mRNA |
CTD |
PMID:21865292 |
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NCBI chr 3:137,329,433...137,334,093
Ensembl chr 3:137,327,373...137,334,094
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DDIT4L |
DNA damage inducible transcript 4 like |
decreases expression |
ISO |
Tacrolimus results in decreased expression of DDIT4L mRNA |
CTD |
PMID:21865292 |
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NCBI chr 4:100,185,870...100,190,468
Ensembl chr 4:100,185,870...100,190,782
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Dhcr24 |
24-dehydrocholesterol reductase |
decreases expression |
ISO |
Tacrolimus results in decreased expression of DHCR24 mRNA |
CTD |
PMID:25270620 |
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NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137
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Dhcr24 |
24-dehydrocholesterol reductase |
decreases expression |
EXP |
Tacrolimus results in decreased expression of DHCR24 mRNA |
CTD |
PMID:25270620 |
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NCBI chr 4:106,418,235...106,446,310
Ensembl chr 4:106,418,235...106,446,310
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DHCR24 |
24-dehydrocholesterol reductase |
decreases expression |
ISO |
Tacrolimus results in decreased expression of DHCR24 mRNA |
CTD |
PMID:25270620 |
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NCBI chr 1:54,849,627...54,887,195
Ensembl chr 1:54,849,627...54,887,195
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Dnajc30 |
DnaJ heat shock protein family (Hsp40) member C30 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of DNAJC30 mRNA |
CTD |
PMID:25270620 |
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NCBI chr12:21,628,323...21,629,389
Ensembl chr12:21,626,450...21,629,408
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M |
Dnajc30 |
DnaJ heat shock protein family (Hsp40) member C30 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of DNAJC30 mRNA |
CTD |
PMID:25270620 |
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NCBI chr 5:135,093,060...135,094,219
Ensembl chr 5:135,093,056...135,094,716
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DNAJC30 |
DnaJ heat shock protein family (Hsp40) member C30 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of DNAJC30 mRNA |
CTD |
PMID:25270620 |
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NCBI chr 7:73,680,918...73,683,453
Ensembl chr 7:73,680,918...73,683,453
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Dnm1l |
dynamin 1-like |
multiple interactions |
ISO |
PINK1 protein affects the reaction [Tacrolimus results in increased phosphorylation of DNM1L protein] Tacrolimus inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein] |
CTD |
PMID:19492085 PMID:26318285 |
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NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
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M |
Dnm1l |
dynamin 1-like |
multiple interactions |
ISO EXP |
PINK1 protein affects the reaction [Tacrolimus results in increased phosphorylation of DNM1L protein] Tacrolimus inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein] |
CTD |
PMID:19492085 PMID:26318285 |
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NCBI chr16:16,130,092...16,176,902
Ensembl chr16:16,130,094...16,176,823
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DNM1L |
dynamin 1 like |
multiple interactions |
EXP ISO |
PINK1 protein affects the reaction [Tacrolimus results in increased phosphorylation of DNM1L protein] Tacrolimus inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein] |
CTD |
PMID:19492085 PMID:26318285 |
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NCBI chr12:32,679,301...32,745,650
Ensembl chr12:32,679,200...32,745,650
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Doc2a |
double C2 domain alpha |
decreases expression |
ISO |
Tacrolimus results in decreased expression of DOC2A mRNA |
CTD |
PMID:25270620 |
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NCBI chr 1:181,457,415...181,462,528
Ensembl chr 1:181,458,390...181,462,030
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Doc2a |
double C2, alpha |
decreases expression |
EXP |
Tacrolimus results in decreased expression of DOC2A mRNA |
CTD |
PMID:25270620 |
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NCBI chr 7:126,446,525...126,451,877
Ensembl chr 7:126,446,588...126,451,877
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DOC2A |
double C2 domain alpha |
decreases expression |
ISO |
Tacrolimus results in decreased expression of DOC2A mRNA |
CTD |
PMID:25270620 |
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NCBI chr16:30,005,514...30,023,228
Ensembl chr16:30,005,514...30,023,270
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Dock10 |
dedicator of cytokinesis 10 |
increases expression |
ISO |
Tacrolimus results in increased expression of DOCK10 mRNA |
CTD |
PMID:29362864 |
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NCBI chr 9:81,843,599...82,101,540
Ensembl chr 9:81,843,604...82,101,525
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M |
Dock10 |
dedicator of cytokinesis 10 |
increases expression |
EXP |
Tacrolimus results in increased expression of DOCK10 mRNA |
CTD |
PMID:29362864 |
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NCBI chr 1:80,478,785...80,736,482
Ensembl chr 1:80,478,790...80,736,244
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DOCK10 |
dedicator of cytokinesis 10 |
increases expression |
ISO |
Tacrolimus results in increased expression of DOCK10 mRNA |
CTD |
PMID:29362864 |
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NCBI chr 2:224,765,090...225,042,468
Ensembl chr 2:224,765,090...225,042,468
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Dpp4 |
dipeptidylpeptidase 4 |
increases activity multiple interactions |
EXP |
Tacrolimus results in increased activity of DPP4 protein MK0626 inhibits the reaction [Tacrolimus results in increased activity of DPP4 protein] |
CTD |
PMID:24959755 |
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NCBI chr 3:46,962,243...47,043,870
Ensembl chr 3:46,962,243...47,043,901
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M |
Dpp4 |
dipeptidylpeptidase 4 |
increases activity multiple interactions |
ISO |
Tacrolimus results in increased activity of DPP4 protein MK0626 inhibits the reaction [Tacrolimus results in increased activity of DPP4 protein] |
CTD |
PMID:24959755 |
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NCBI chr 2:62,160,417...62,242,635
Ensembl chr 2:62,160,417...62,242,575
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H |
DPP4 |
dipeptidyl peptidase 4 |
increases activity multiple interactions |
ISO |
Tacrolimus results in increased activity of DPP4 protein MK0626 inhibits the reaction [Tacrolimus results in increased activity of DPP4 protein] |
CTD |
PMID:24959755 |
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NCBI chr 2:161,992,245...162,074,215
Ensembl chr 2:161,992,245...162,074,394
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Drd2 |
dopamine receptor D2 |
affects activity multiple interactions |
EXP |
Tacrolimus affects the activity of DRD2 protein Sulpiride inhibits the reaction [Tacrolimus affects the activity of DRD2 protein] |
CTD |
PMID:15332494 |
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NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
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M |
Drd2 |
dopamine receptor D2 |
affects activity multiple interactions |
ISO |
Tacrolimus affects the activity of DRD2 protein Sulpiride inhibits the reaction [Tacrolimus affects the activity of DRD2 protein] |
CTD |
PMID:15332494 |
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NCBI chr 9:49,251,633...49,319,477
Ensembl chr 9:49,251,927...49,319,477
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H |
DRD2 |
dopamine receptor D2 |
affects activity multiple interactions |
ISO |
Tacrolimus affects the activity of DRD2 protein Sulpiride inhibits the reaction [Tacrolimus affects the activity of DRD2 protein] |
CTD |
PMID:15332494 |
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NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
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M |
Ear1 |
eosinophil-associated, ribonuclease A family, member 1 |
increases expression |
EXP |
Tacrolimus results in increased expression of EAR1 mRNA |
CTD |
PMID:29362864 |
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NCBI chr14:44,056,222...44,057,096
Ensembl chr14:44,056,222...44,112,974
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R |
Ech1 |
enoyl-CoA hydratase 1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ECH1 mRNA |
CTD |
PMID:25270620 |
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NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
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M |
Ech1 |
enoyl coenzyme A hydratase 1, peroxisomal |
decreases expression |
EXP |
Tacrolimus results in decreased expression of ECH1 mRNA |
CTD |
PMID:25270620 |
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NCBI chr 7:28,524,763...28,531,664
Ensembl chr 7:28,524,642...28,531,672
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H |
ECH1 |
enoyl-CoA hydratase 1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ECH1 mRNA |
CTD |
PMID:25270620 |
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NCBI chr19:38,815,422...38,831,794
Ensembl chr19:38,815,422...38,831,841
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R |
Edem1 |
ER degradation enhancing alpha-mannosidase like protein 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of EDEM1 mRNA |
CTD |
PMID:25270620 |
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NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
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M |
Edem1 |
ER degradation enhancer, mannosidase alpha-like 1 |
increases expression |
EXP |
Tacrolimus results in increased expression of EDEM1 mRNA |
CTD |
PMID:25270620 |
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NCBI chr 6:108,800,984...108,836,317
Ensembl chr 6:108,805,602...108,836,317
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H |
EDEM1 |
ER degradation enhancing alpha-mannosidase like protein 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of EDEM1 mRNA |
CTD |
PMID:25270620 |
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NCBI chr 3:5,187,707...5,219,958
Ensembl chr 3:5,187,646...5,219,958
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Edn1 |
endothelin 1 |
increases expression |
EXP |
Tacrolimus results in increased expression of EDN1 mRNA; Tacrolimus results in increased expression of EDN1 protein |
CTD |
PMID:9517403 PMID:9931093 |
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NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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M |
Edn1 |
endothelin 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of EDN1 mRNA; Tacrolimus results in increased expression of EDN1 protein |
CTD |
PMID:9517403 PMID:9931093 |
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NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
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EDN1 |
endothelin 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of EDN1 mRNA; Tacrolimus results in increased expression of EDN1 protein |
CTD |
PMID:9517403 PMID:9931093 |
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NCBI chr 6:12,256,484...12,297,194
Ensembl chr 6:12,290,361...12,297,194
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R |
Ednra |
endothelin receptor type A |
increases activity increases expression |
EXP |
Tacrolimus results in increased activity of EDNRA protein Tacrolimus results in increased expression of EDNRA mRNA |
CTD |
PMID:8587392 PMID:15964565 |
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NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
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M |
Ednra |
endothelin receptor type A |
increases activity increases expression |
ISO |
Tacrolimus results in increased activity of EDNRA protein Tacrolimus results in increased expression of EDNRA mRNA |
CTD |
PMID:8587392 PMID:15964565 |
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NCBI chr 8:78,389,658...78,451,081
Ensembl chr 8:78,389,660...78,451,093
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H |
EDNRA |
endothelin receptor type A |
increases activity increases expression |
ISO |
Tacrolimus results in increased activity of EDNRA protein Tacrolimus results in increased expression of EDNRA mRNA |
CTD |
PMID:8587392 PMID:15964565 |
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NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954
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R |
Efemp2 |
EGF containing fibulin extracellular matrix protein 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of EFEMP2 mRNA |
CTD |
PMID:29362864 |
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NCBI chr 1:202,781,692...202,789,784
Ensembl chr 1:202,781,665...202,789,414
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M |
Efemp2 |
epidermal growth factor-containing fibulin-like extracellular matrix protein 2 |
increases expression |
EXP |
Tacrolimus results in increased expression of EFEMP2 mRNA |
CTD |
PMID:29362864 |
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NCBI chr19:5,523,974...5,532,548
Ensembl chr19:5,523,982...5,532,545
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H |
EFEMP2 |
EGF containing fibulin extracellular matrix protein 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of EFEMP2 mRNA |
CTD |
PMID:29362864 |
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NCBI chr11:65,866,441...65,872,800
Ensembl chr11:65,866,441...65,873,592
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R |
Egr1 |
early growth response 1 |
increases expression |
EXP |
Tacrolimus results in increased expression of EGR1 mRNA |
CTD |
PMID:21865292 |
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NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
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G |
M |
Egr1 |
early growth response 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of EGR1 mRNA |
CTD |
PMID:21865292 |
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NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
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G |
H |
EGR1 |
early growth response 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of EGR1 mRNA |
CTD |
PMID:21865292 |
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NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
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G |
R |
Egr2 |
early growth response 2 |
increases expression |
EXP |
Tacrolimus results in increased expression of EGR2 mRNA |
CTD |
PMID:21865292 |
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NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
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G |
M |
Egr2 |
early growth response 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of EGR2 mRNA |
CTD |
PMID:21865292 |
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NCBI chr10:67,370,334...67,383,354
Ensembl chr10:67,371,305...67,378,018
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G |
H |
EGR2 |
early growth response 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of EGR2 mRNA |
CTD |
PMID:21865292 |
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NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,819,167
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G |
R |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [Sirolimus results in decreased phosphorylation of and results in increased activity of EIF4EBP1 protein] |
CTD |
PMID:8599949 |
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NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
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G |
M |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions |
EXP |
Tacrolimus inhibits the reaction [Sirolimus results in decreased phosphorylation of and results in increased activity of EIF4EBP1 protein] |
CTD |
PMID:8599949 |
|
NCBI chr 8:27,750,355...27,765,684
Ensembl chr 8:27,750,357...27,766,702
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G |
H |
EIF4EBP1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [Sirolimus results in decreased phosphorylation of and results in increased activity of EIF4EBP1 protein] |
CTD |
PMID:8599949 |
|
NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365
|
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G |
R |
Elac2 |
elaC ribonuclease Z 2 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ELAC2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr10:49,632,308...49,655,614
Ensembl chr10:49,632,378...49,655,614
|
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G |
M |
Elac2 |
elaC ribonuclease Z 2 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of ELAC2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr11:64,869,856...64,892,906
Ensembl chr11:64,869,864...64,892,895
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G |
H |
ELAC2 |
elaC ribonuclease Z 2 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of ELAC2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr17:12,991,612...13,018,027
Ensembl chr17:12,991,612...13,018,065
|
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G |
R |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
increases phosphorylation |
ISO |
Tacrolimus results in increased phosphorylation of ERN1 protein |
CTD |
PMID:23958496 |
|
NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
|
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G |
M |
Ern1 |
endoplasmic reticulum (ER) to nucleus signalling 1 |
increases phosphorylation |
EXP |
Tacrolimus results in increased phosphorylation of ERN1 protein |
CTD |
PMID:23958496 |
|
NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678
|
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G |
H |
ERN1 |
endoplasmic reticulum to nucleus signaling 1 |
increases phosphorylation |
ISO |
Tacrolimus results in increased phosphorylation of ERN1 protein |
CTD |
PMID:23958496 |
|
NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819
|
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G |
R |
Ero1a |
endoplasmic reticulum oxidoreductase 1 alpha |
increases expression |
ISO |
Tacrolimus results in increased expression of ERO1A mRNA |
CTD |
PMID:23958496 |
|
NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
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G |
M |
Ero1a |
endoplasmic reticulum oxidoreductase 1 alpha |
increases expression |
EXP |
Tacrolimus results in increased expression of ERO1A mRNA |
CTD |
PMID:23958496 |
|
NCBI chr14:45,520,544...45,556,029
Ensembl chr14:45,520,544...45,556,228
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G |
H |
ERO1A |
endoplasmic reticulum oxidoreductase 1 alpha |
increases expression |
ISO |
Tacrolimus results in increased expression of ERO1A mRNA |
CTD |
PMID:23958496 |
|
NCBI chr14:52,639,915...52,695,558
Ensembl chr14:52,639,915...52,695,900
|
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G |
R |
Exosc4 |
exosome component 4 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of EXOSC4 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 7:108,047,831...108,050,573
Ensembl chr 7:108,047,831...108,050,573
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G |
M |
Exosc4 |
exosome component 4 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of EXOSC4 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr15:76,211,597...76,214,870
Ensembl chr15:76,211,597...76,214,877
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G |
H |
EXOSC4 |
exosome component 4 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of EXOSC4 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 8:144,064,056...144,080,648
Ensembl chr 8:144,078,648...144,080,648
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G |
R |
F2r |
coagulation factor II (thrombin) receptor |
decreases expression |
ISO |
Tacrolimus results in decreased expression of F2R mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
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G |
M |
F2r |
coagulation factor II (thrombin) receptor |
decreases expression |
EXP |
Tacrolimus results in decreased expression of F2R mRNA |
CTD |
PMID:25270620 |
|
NCBI chr13:95,738,288...95,754,974
Ensembl chr13:95,738,311...95,754,995
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G |
H |
F2R |
coagulation factor II thrombin receptor |
decreases expression |
ISO |
Tacrolimus results in decreased expression of F2R mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 5:76,716,126...76,735,770
Ensembl chr 5:76,716,126...76,735,770
|
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G |
R |
Fabp2 |
fatty acid binding protein 2 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of FABP2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089
|
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G |
M |
Fabp2 |
fatty acid binding protein 2, intestinal |
decreases expression |
EXP |
Tacrolimus results in decreased expression of FABP2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 3:122,688,721...122,693,155
Ensembl chr 3:122,688,721...122,693,155
|
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G |
H |
FABP2 |
fatty acid binding protein 2 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of FABP2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 4:119,317,250...119,322,138
Ensembl chr 4:119,317,250...119,322,138
|
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G |
R |
Fas |
Fas cell surface death receptor |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP8 protein]; Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP9 protein] |
CTD |
PMID:15548389 |
|
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
|
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G |
M |
Fas |
Fas (TNF receptor superfamily member 6) |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP8 protein]; Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP9 protein] |
CTD |
PMID:15548389 |
|
NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
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G |
H |
FAS |
Fas cell surface death receptor |
multiple interactions |
EXP |
Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP8 protein]; Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP9 protein] |
CTD |
PMID:15548389 |
|
NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
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G |
M |
Fasl |
Fas ligand (TNF superfamily, member 6) |
decreases secretion |
ISO |
Tacrolimus results in decreased secretion of FASLG protein |
CTD |
PMID:11692113 |
|
NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
|
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G |
R |
Faslg |
Fas ligand |
decreases secretion |
ISO |
Tacrolimus results in decreased secretion of FASLG protein |
CTD |
PMID:11692113 |
|
NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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G |
H |
FASLG |
Fas ligand |
decreases secretion |
EXP |
Tacrolimus results in decreased secretion of FASLG protein |
CTD |
PMID:11692113 |
|
NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
|
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G |
R |
Fbln1 |
fibulin 1 |
increases expression |
EXP |
Tacrolimus results in increased expression of FBLN1 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
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G |
M |
Fbln1 |
fibulin 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of FBLN1 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr15:85,090,150...85,170,495
Ensembl chr15:85,090,150...85,170,736
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G |
H |
FBLN1 |
fibulin 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of FBLN1 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr22:45,502,883...45,601,135
Ensembl chr22:45,502,238...45,601,135
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G |
R |
Fga |
fibrinogen alpha chain |
increases expression |
EXP |
Tacrolimus results in increased expression of FGA mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528
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G |
M |
Fga |
fibrinogen alpha chain |
increases expression |
ISO |
Tacrolimus results in increased expression of FGA mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
|
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G |
H |
FGA |
fibrinogen alpha chain |
increases expression |
ISO |
Tacrolimus results in increased expression of FGA mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,128...154,590,745
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G |
R |
Fgb |
fibrinogen beta chain |
increases expression |
EXP |
Tacrolimus results in increased expression of FGB mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
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G |
M |
Fgb |
fibrinogen beta chain |
increases expression |
ISO |
Tacrolimus results in increased expression of FGB mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170
|
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G |
H |
FGB |
fibrinogen beta chain |
increases expression |
ISO |
Tacrolimus results in increased expression of FGB mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
|
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G |
R |
Fgd2 |
FYVE, RhoGEF and PH domain containing 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of FGD2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr20:7,424,795...7,441,603
Ensembl chr20:7,424,790...7,441,603
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G |
M |
Fgd2 |
FYVE, RhoGEF and PH domain containing 2 |
increases expression |
EXP |
Tacrolimus results in increased expression of FGD2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr17:29,579,878...29,598,509
Ensembl chr17:29,579,888...29,598,635
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G |
H |
FGD2 |
FYVE, RhoGEF and PH domain containing 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of FGD2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 6:37,005,655...37,029,069
Ensembl chr 6:37,005,646...37,029,069
|
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G |
R |
Fgf21 |
fibroblast growth factor 21 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of FGF21 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 1:96,083,495...96,084,738
Ensembl chr 1:96,083,441...96,090,454
|
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G |
M |
Fgf21 |
fibroblast growth factor 21 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of FGF21 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 7:45,263,314...45,264,914
Ensembl chr 7:45,263,310...45,264,914
|
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G |
H |
FGF21 |
fibroblast growth factor 21 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of FGF21 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr19:48,755,524...48,758,330
Ensembl chr19:48,755,524...48,758,333
|
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G |
R |
Fgl2 |
fibrinogen-like 2 |
increases expression |
EXP ISO |
Tacrolimus results in increased expression of FGL2 mRNA |
CTD |
PMID:21865292 PMID:29362864 |
|
NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207
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G |
M |
Fgl2 |
fibrinogen-like protein 2 |
increases expression |
ISO EXP |
Tacrolimus results in increased expression of FGL2 mRNA |
CTD |
PMID:21865292 PMID:29362864 |
|
NCBI chr 5:21,577,671...21,583,384
Ensembl chr 5:21,577,640...21,583,372
|
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G |
H |
FGL2 |
fibrinogen like 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of FGL2 mRNA |
CTD |
PMID:21865292 PMID:29362864 |
|
NCBI chr 7:77,193,369...77,199,819
Ensembl chr 7:77,193,369...77,199,848
|
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G |
R |
Fhl2 |
four and a half LIM domains 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of FHL2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 9:45,388,979...45,462,530
Ensembl chr 9:45,388,981...45,431,192
|
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G |
M |
Fhl2 |
four and a half LIM domains 2 |
increases expression |
EXP |
Tacrolimus results in increased expression of FHL2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 1:43,162,231...43,237,503
Ensembl chr 1:43,162,234...43,236,144
|
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G |
H |
FHL2 |
four and a half LIM domains 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of FHL2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 2:105,357,712...105,438,529
Ensembl chr 2:105,357,712...105,438,513
|
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G |
R |
Fkbp1a |
FKBP prolyl isomerase 1A |
multiple interactions increases expression |
ISO EXP |
[Tacrolimus binds to FKBP1A protein] inhibits the reaction [Sirolimus binds to FKBP1A protein]; [Tacrolimus inhibits the reaction [FKBP1A protein binds to ACVR1B protein]] which results in decreased ubiquitination of ACVR1B protein; Tacrolimus inhibits the reaction [FKBP1A protein binds to and results in decreased activity of ACVR1B protein]; Tacrolimus inhibits the reaction [FKBP1A protein promotes the reaction [SMURF1 protein binds to SMAD7 protein binds to ACVR1B protein]] Tacrolimus results in increased expression of FKBP1A protein |
CTD |
PMID:10361256 PMID:11041285 PMID:16720724 |
|
NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
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G |
M |
Fkbp1a |
FK506 binding protein 1a |
multiple interactions increases expression |
ISO |
[Tacrolimus binds to FKBP1A protein] inhibits the reaction [Sirolimus binds to FKBP1A protein]; [Tacrolimus inhibits the reaction [FKBP1A protein binds to ACVR1B protein]] which results in decreased ubiquitination of ACVR1B protein; Tacrolimus inhibits the reaction [FKBP1A protein binds to and results in decreased activity of ACVR1B protein]; Tacrolimus inhibits the reaction [FKBP1A protein promotes the reaction [SMURF1 protein binds to SMAD7 protein binds to ACVR1B protein]] Tacrolimus results in increased expression of FKBP1A protein |
CTD |
PMID:10361256 PMID:11041285 PMID:16720724 |
|
NCBI chr 2:151,384,403...151,403,611
Ensembl chr 2:151,384,403...151,403,612
|
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G |
H |
FKBP1A |
FKBP prolyl isomerase 1A |
multiple interactions increases expression |
EXP ISO |
[Tacrolimus binds to FKBP1A protein] inhibits the reaction [Sirolimus binds to FKBP1A protein]; [Tacrolimus inhibits the reaction [FKBP1A protein binds to ACVR1B protein]] which results in decreased ubiquitination of ACVR1B protein; Tacrolimus inhibits the reaction [FKBP1A protein binds to and results in decreased activity of ACVR1B protein]; Tacrolimus inhibits the reaction [FKBP1A protein promotes the reaction [SMURF1 protein binds to SMAD7 protein binds to ACVR1B protein]] Tacrolimus results in increased expression of FKBP1A protein |
CTD |
PMID:10361256 PMID:11041285 PMID:16720724 |
|
NCBI chr20:1,368,978...1,393,054
Ensembl chr20:1,368,977...1,393,164
|
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G |
R |
Fkbp5 |
FKBP prolyl isomerase 5 |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [NR3C1 protein binds to FKBP5 protein] |
CTD |
PMID:15697228 |
|
NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
|
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G |
M |
Fkbp5 |
FK506 binding protein 5 |
multiple interactions |
EXP |
Tacrolimus inhibits the reaction [NR3C1 protein binds to FKBP5 protein] |
CTD |
PMID:15697228 |
|
NCBI chr17:28,617,727...28,705,123
Ensembl chr17:28,618,068...28,736,501
|
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G |
H |
FKBP5 |
FKBP prolyl isomerase 5 |
multiple interactions |
ISO |
Tacrolimus inhibits the reaction [NR3C1 protein binds to FKBP5 protein] |
CTD |
PMID:15697228 |
|
NCBI chr 6:35,573,590...35,728,583
Ensembl chr 6:35,573,585...35,728,583
|
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G |
R |
Flt3 |
Fms related receptor tyrosine kinase 3 |
increases expression |
ISO |
Tacrolimus results in increased expression of FLT3 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr12:7,623,658...7,699,474
Ensembl chr12:7,623,930...7,699,474
|
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G |
M |
Flt3 |
FMS-like tyrosine kinase 3 |
increases expression |
EXP |
Tacrolimus results in increased expression of FLT3 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 5:147,267,551...147,337,299
Ensembl chr 5:147,267,551...147,337,299
|
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G |
H |
FLT3 |
fms related receptor tyrosine kinase 3 |
increases expression |
ISO |
Tacrolimus results in increased expression of FLT3 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr13:28,003,274...28,100,576
Ensembl chr13:28,003,274...28,100,592
|
|
G |
R |
Fmo2 |
flavin containing dimethylaniline monoxygenase 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of FMO2 mRNA |
CTD |
PMID:21621594 |
|
NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
|
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G |
M |
Fmo2 |
flavin containing monooxygenase 2 |
increases expression |
EXP |
Tacrolimus results in increased expression of FMO2 mRNA |
CTD |
PMID:21621594 |
|
NCBI chr 1:162,701,886...162,726,327
Ensembl chr 1:162,701,886...162,726,295
|
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G |
H |
FMO2 |
flavin containing dimethylaniline monoxygenase 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of FMO2 mRNA |
CTD |
PMID:21621594 |
|
NCBI chr 1:171,185,208...171,212,686
Ensembl chr 1:171,185,249...171,212,686
|
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G |
R |
Fn1 |
fibronectin 1 |
multiple interactions increases expression |
ISO |
Tacrolimus inhibits the reaction [NPR1 protein affects the expression of FN1 mRNA] Tacrolimus results in increased expression of FN1 mRNA |
CTD |
PMID:15939815 PMID:29362864 |
|
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
|
|
G |
M |
Fn1 |
fibronectin 1 |
multiple interactions increases expression |
EXP ISO |
Tacrolimus inhibits the reaction [NPR1 protein affects the expression of FN1 mRNA] Tacrolimus results in increased expression of FN1 mRNA |
CTD |
PMID:15939815 PMID:29362864 |
|
NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359
|
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G |
H |
FN1 |
fibronectin 1 |
multiple interactions increases expression |
ISO EXP |
Tacrolimus inhibits the reaction [NPR1 protein affects the expression of FN1 mRNA] Tacrolimus results in increased expression of FN1 mRNA |
CTD |
PMID:15939815 PMID:29362864 |
|
NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
|
|
G |
R |
Fndc3a |
fibronectin type III domain containing 3a |
increases expression |
ISO |
Tacrolimus results in increased expression of FNDC3A mRNA |
CTD |
PMID:25270620 |
|
NCBI chr15:47,689,909...47,867,354
Ensembl chr15:47,689,919...47,866,784
|
|
G |
M |
Fndc3a |
fibronectin type III domain containing 3A |
increases expression |
EXP |
Tacrolimus results in increased expression of FNDC3A mRNA |
CTD |
PMID:25270620 |
|
NCBI chr14:72,775,393...72,948,141
Ensembl chr14:72,775,386...72,947,443
|
|
G |
H |
FNDC3A |
fibronectin type III domain containing 3A |
increases expression |
ISO |
Tacrolimus results in increased expression of FNDC3A mRNA |
CTD |
PMID:25270620 |
|
NCBI chr13:48,975,291...49,209,779
Ensembl chr13:48,975,912...49,209,779
|
|
G |
R |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
Tacrolimus results in increased expression of FOS mRNA |
CTD |
PMID:23958496 |
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
|
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G |
M |
Fos |
FBJ osteosarcoma oncogene |
increases expression |
EXP |
Tacrolimus results in increased expression of FOS mRNA |
CTD |
PMID:23958496 |
|
NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
|
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G |
H |
FOS |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
Tacrolimus results in increased expression of FOS mRNA |
CTD |
PMID:23958496 |
|
NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
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G |
R |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
increases expression |
ISO |
Tacrolimus results in increased expression of FOSL1 mRNA |
CTD |
PMID:23958496 |
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NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
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G |
M |
Fosl1 |
fos-like antigen 1 |
increases expression |
EXP |
Tacrolimus results in increased expression of FOSL1 mRNA |
CTD |
PMID:23958496 |
|
NCBI chr19:5,497,726...5,505,966
Ensembl chr19:5,497,575...5,505,974
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G |
H |
FOSL1 |
FOS like 1, AP-1 transcription factor subunit |
increases expression |
ISO |
Tacrolimus results in increased expression of FOSL1 mRNA |
CTD |
PMID:23958496 |
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NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573
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G |
R |
Gbp1 |
guanylate binding protein 1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of GBP1 mRNA |
CTD |
PMID:21621594 |
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NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131
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G |
H |
GBP1 |
guanylate binding protein 1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of GBP1 mRNA |
CTD |
PMID:21621594 |
|
NCBI chr 1:89,052,319...89,065,208
Ensembl chr 1:89,051,882...89,065,360
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G |
M |
Gbp2b |
guanylate binding protein 2b |
decreases expression |
EXP |
Tacrolimus results in decreased expression of GBP1 mRNA |
CTD |
PMID:21621594 |
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NCBI chr 3:142,300,577...142,324,940
Ensembl chr 3:142,300,608...142,324,940
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G |
R |
Gc |
GC, vitamin D binding protein |
decreases expression increases expression |
EXP ISO |
Tacrolimus results in decreased expression of GC mRNA Tacrolimus results in increased expression of GC mRNA |
CTD |
PMID:21865292 PMID:29362864 |
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NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
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G |
M |
Gc |
vitamin D binding protein |
decreases expression increases expression |
ISO EXP |
Tacrolimus results in decreased expression of GC mRNA Tacrolimus results in increased expression of GC mRNA |
CTD |
PMID:21865292 PMID:29362864 |
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NCBI chr 5:89,565,370...89,605,757
Ensembl chr 5:89,565,381...89,605,757
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G |
H |
GC |
GC vitamin D binding protein |
decreases expression increases expression |
ISO |
Tacrolimus results in decreased expression of GC mRNA Tacrolimus results in increased expression of GC mRNA |
CTD |
PMID:21865292 PMID:29362864 |
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NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041
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G |
R |
Gcg |
glucagon |
multiple interactions decreases secretion |
EXP |
MK0626 inhibits the reaction [Tacrolimus results in decreased secretion of GCG protein modified form] |
CTD |
PMID:24959755 |
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NCBI chr 3:47,113,914...47,122,929
Ensembl chr 3:47,113,914...47,122,929
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G |
M |
Gcg |
glucagon |
multiple interactions decreases secretion |
ISO |
MK0626 inhibits the reaction [Tacrolimus results in decreased secretion of GCG protein modified form] |
CTD |
PMID:24959755 |
|
NCBI chr 2:62,304,874...62,313,997
Ensembl chr 2:62,304,874...62,313,994
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G |
H |
GCG |
glucagon |
multiple interactions decreases secretion |
ISO |
MK0626 inhibits the reaction [Tacrolimus results in decreased secretion of GCG protein modified form] |
CTD |
PMID:24959755 |
|
NCBI chr 2:162,142,882...162,152,247
Ensembl chr 2:162,142,882...162,152,404
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G |
R |
Gins2 |
GINS complex subunit 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of GINS2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339
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G |
M |
Gins2 |
GINS complex subunit 2 (Psf2 homolog) |
increases expression |
EXP |
Tacrolimus results in increased expression of GINS2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 8:121,308,005...121,315,814
Ensembl chr 8:121,305,372...121,316,043
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G |
H |
GINS2 |
GINS complex subunit 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of GINS2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr16:85,676,198...85,688,954
Ensembl chr16:85,676,198...85,690,073
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G |
R |
Gjb1 |
gap junction protein, beta 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of GJB1 mRNA |
CTD |
PMID:21621594 |
|
NCBI chr X:66,501,848...66,509,783
Ensembl chr X:66,501,820...66,509,925
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G |
M |
Gjb1 |
gap junction protein, beta 1 |
increases expression |
EXP |
Tacrolimus results in increased expression of GJB1 mRNA |
CTD |
PMID:21621594 |
|
NCBI chr X:100,419,982...100,429,235
Ensembl chr X:100,419,984...100,429,235
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G |
H |
GJB1 |
gap junction protein beta 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of GJB1 mRNA |
CTD |
PMID:21621594 |
|
NCBI chr X:71,215,239...71,225,516
Ensembl chr X:71,212,811...71,225,516
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G |
R |
Gldc |
glycine decarboxylase |
decreases expression |
ISO |
Tacrolimus results in decreased expression of GLDC mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 1:227,883,247...227,962,119
Ensembl chr 1:227,883,249...227,962,097
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G |
M |
Gldc |
glycine decarboxylase |
decreases expression |
EXP |
Tacrolimus results in decreased expression of GLDC mRNA |
CTD |
PMID:25270620 |
|
NCBI chr19:30,075,841...30,152,841
Ensembl chr19:30,075,847...30,152,829
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G |
H |
GLDC |
glycine decarboxylase |
decreases expression |
ISO |
Tacrolimus results in decreased expression of GLDC mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 9:6,532,467...6,645,729
Ensembl chr 9:6,532,467...6,645,729
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G |
R |
Glp1r |
glucagon-like peptide 1 receptor |
decreases expression multiple interactions |
EXP |
Tacrolimus results in decreased expression of GLP1R protein MK0626 inhibits the reaction [Tacrolimus results in decreased expression of GLP1R protein] |
CTD |
PMID:24959755 |
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NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241
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G |
M |
Glp1r |
glucagon-like peptide 1 receptor |
decreases expression multiple interactions |
ISO |
Tacrolimus results in decreased expression of GLP1R protein MK0626 inhibits the reaction [Tacrolimus results in decreased expression of GLP1R protein] |
CTD |
PMID:24959755 |
|
NCBI chr17:31,120,841...31,155,484
Ensembl chr17:31,120,791...31,159,765
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G |
H |
GLP1R |
glucagon like peptide 1 receptor |
decreases expression multiple interactions |
ISO |
Tacrolimus results in decreased expression of GLP1R protein MK0626 inhibits the reaction [Tacrolimus results in decreased expression of GLP1R protein] |
CTD |
PMID:24959755 |
|
NCBI chr 6:39,048,781...39,091,303
Ensembl chr 6:39,048,781...39,091,303
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G |
R |
Gpihbp1 |
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of GPIHBP1 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 7:107,285,584...107,288,702
Ensembl chr 7:107,285,654...107,288,702
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G |
M |
Gpihbp1 |
GPI-anchored HDL-binding protein 1 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of GPIHBP1 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr15:75,468,479...75,470,062
Ensembl chr15:75,468,477...75,471,330
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G |
H |
GPIHBP1 |
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of GPIHBP1 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 8:143,213,218...143,217,170
Ensembl chr 8:143,213,218...143,217,170
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G |
R |
Gpn2 |
GPN-loop GTPase 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of GPN2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 5:145,809,455...145,817,252
Ensembl chr 5:145,809,651...145,817,252
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G |
M |
Gpn2 |
GPN-loop GTPase 2 |
increases expression |
EXP |
Tacrolimus results in increased expression of GPN2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 4:133,311,684...133,319,046
Ensembl chr 4:133,311,673...133,319,046
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G |
H |
GPN2 |
GPN-loop GTPase 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of GPN2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 1:26,876,132...26,890,283
Ensembl chr 1:26,876,132...26,890,283
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G |
R |
Gpnmb |
glycoprotein nmb |
increases expression |
EXP |
Tacrolimus results in increased expression of GPNMB mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
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G |
M |
Gpnmb |
glycoprotein (transmembrane) nmb |
increases expression |
ISO |
Tacrolimus results in increased expression of GPNMB mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 6:49,013,449...49,044,413
Ensembl chr 6:49,013,480...49,047,863
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G |
H |
GPNMB |
glycoprotein nmb |
increases expression |
ISO |
Tacrolimus results in increased expression of GPNMB mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 7:23,246,775...23,275,108
Ensembl chr 7:23,235,967...23,275,108
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G |
R |
Grn |
granulin precursor |
increases expression |
ISO |
Tacrolimus results in increased expression of GRN mRNA |
CTD |
PMID:25270620 |
|
NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
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G |
M |
Grn |
granulin |
increases expression |
EXP |
Tacrolimus results in increased expression of GRN mRNA |
CTD |
PMID:25270620 |
|
NCBI chr11:102,321,333...102,327,635
Ensembl chr11:102,321,141...102,327,874
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G |
H |
GRN |
granulin precursor |
increases expression |
ISO |
Tacrolimus results in increased expression of GRN mRNA |
CTD |
PMID:25270620 |
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NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106
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G |
R |
Gsk3a |
glycogen synthase kinase 3 alpha |
multiple interactions increases phosphorylation |
ISO |
[GSK3A protein co-treated with GSK3B protein] affects the reaction [Tacrolimus results in increased expression of SNAI1 protein] Tacrolimus results in increased phosphorylation of GSK3A protein |
CTD |
PMID:22416070 |
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NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
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G |
M |
Gsk3a |
glycogen synthase kinase 3 alpha |
multiple interactions increases phosphorylation |
ISO |
[GSK3A protein co-treated with GSK3B protein] affects the reaction [Tacrolimus results in increased expression of SNAI1 protein] Tacrolimus results in increased phosphorylation of GSK3A protein |
CTD |
PMID:22416070 |
|
NCBI chr 7:24,927,683...24,937,276
Ensembl chr 7:24,927,683...24,937,276
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G |
H |
GSK3A |
glycogen synthase kinase 3 alpha |
multiple interactions increases phosphorylation |
EXP |
[GSK3A protein co-treated with GSK3B protein] affects the reaction [Tacrolimus results in increased expression of SNAI1 protein] Tacrolimus results in increased phosphorylation of GSK3A protein |
CTD |
PMID:22416070 |
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NCBI chr19:42,230,190...42,242,602
Ensembl chr19:42,226,225...42,242,625
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G |
R |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions increases phosphorylation |
ISO |
[GSK3A protein co-treated with GSK3B protein] affects the reaction [Tacrolimus results in increased expression of SNAI1 protein] Tacrolimus results in increased phosphorylation of GSK3B protein |
CTD |
PMID:22416070 |
|
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
M |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions increases phosphorylation |
ISO |
[GSK3A protein co-treated with GSK3B protein] affects the reaction [Tacrolimus results in increased expression of SNAI1 protein] Tacrolimus results in increased phosphorylation of GSK3B protein |
CTD |
PMID:22416070 |
|
NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
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G |
H |
GSK3B |
glycogen synthase kinase 3 beta |
multiple interactions increases phosphorylation |
EXP |
[GSK3A protein co-treated with GSK3B protein] affects the reaction [Tacrolimus results in increased expression of SNAI1 protein] Tacrolimus results in increased phosphorylation of GSK3B protein |
CTD |
PMID:22416070 |
|
NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
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G |
R |
Gtpbp4 |
GTP binding protein 4 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of GTPBP4 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr17:61,308,033...61,328,184
Ensembl chr17:61,308,014...61,418,009
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G |
M |
Gtpbp4 |
GTP binding protein 4 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of GTPBP4 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr13:9,022,106...9,046,144
Ensembl chr13:9,016,367...9,046,119
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G |
H |
GTPBP4 |
GTP binding protein 4 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of GTPBP4 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr10:988,434...1,019,932
Ensembl chr10:988,434...1,019,932
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G |
R |
Guca2a |
guanylate cyclase activator 2A |
increases expression |
EXP |
Tacrolimus results in increased expression of GUCA2A mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 5:133,237,177...133,239,019
Ensembl chr 5:133,237,177...133,239,018
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G |
M |
Guca2a |
guanylate cyclase activator 2a (guanylin) |
increases expression |
ISO |
Tacrolimus results in increased expression of GUCA2A mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 4:119,494,929...119,496,662
Ensembl chr 4:119,494,901...119,496,668
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G |
H |
GUCA2A |
guanylate cyclase activator 2A |
increases expression |
ISO |
Tacrolimus results in increased expression of GUCA2A mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 1:42,162,690...42,164,745
Ensembl chr 1:42,162,690...42,164,745
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G |
M |
H2ac23 |
H2A clustered histone 23 |
increases expression |
EXP |
Tacrolimus results in increased expression of H2AC23 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr13:21,994,537...21,995,088
Ensembl chr13:21,994,635...21,995,114
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G |
R |
Hadhb |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta |
decreases expression |
ISO |
Tacrolimus results in decreased expression of HADHB mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
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G |
M |
Hadhb |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta |
decreases expression |
EXP |
Tacrolimus results in decreased expression of HADHB mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 5:30,360,251...30,389,591
Ensembl chr 5:30,360,246...30,389,591
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G |
H |
HADHB |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta |
decreases expression |
ISO |
Tacrolimus results in decreased expression of HADHB mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 2:26,244,939...26,290,465
Ensembl chr 2:26,243,170...26,290,465
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G |
R |
Havcr1 |
hepatitis A virus cellular receptor 1 |
increases expression |
EXP |
Tacrolimus results in increased expression of HAVCR1 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
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G |
M |
Havcr1 |
hepatitis A virus cellular receptor 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of HAVCR1 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405
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G |
H |
HAVCR1 |
hepatitis A virus cellular receptor 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of HAVCR1 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396
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G |
R |
Herpud1 |
homocysteine inducible ER protein with ubiquitin like domain 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of HERPUD1 mRNA |
CTD |
PMID:23958496 PMID:25270620 |
|
NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
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G |
M |
Herpud1 |
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
increases expression |
EXP |
Tacrolimus results in increased expression of HERPUD1 mRNA |
CTD |
PMID:23958496 PMID:25270620 |
|
NCBI chr 8:95,113,057...95,121,999
Ensembl chr 8:95,113,066...95,122,005
|
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G |
H |
HERPUD1 |
homocysteine inducible ER protein with ubiquitin like domain 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of HERPUD1 mRNA |
CTD |
PMID:23958496 PMID:25270620 |
|
NCBI chr16:56,932,142...56,944,864
Ensembl chr16:56,932,142...56,944,864
|
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G |
R |
Hexa |
hexosaminidase subunit alpha |
increases expression |
ISO |
Tacrolimus results in increased expression of HEXA mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013
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G |
M |
Hexa |
hexosaminidase A |
increases expression |
EXP |
Tacrolimus results in increased expression of HEXA mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 9:59,446,574...59,472,392
Ensembl chr 9:59,446,823...59,472,392
|
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G |
H |
HEXA |
hexosaminidase subunit alpha |
increases expression |
ISO |
Tacrolimus results in increased expression of HEXA mRNA |
CTD |
PMID:25270620 |
|
NCBI chr15:72,340,924...72,376,014
Ensembl chr15:72,340,924...72,376,420
|
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G |
R |
Hgs |
hepatocyte growth factor-regulated tyrosine kinase substrate |
increases expression |
ISO |
Tacrolimus results in increased expression of HGS mRNA |
CTD |
PMID:29380240 |
|
NCBI chr10:105,739,617...105,757,838
Ensembl chr10:105,739,296...105,757,835
|
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G |
M |
Hgs |
HGF-regulated tyrosine kinase substrate |
increases expression |
ISO |
Tacrolimus results in increased expression of HGS mRNA |
CTD |
PMID:29380240 |
|
NCBI chr11:120,358,431...120,374,810
Ensembl chr11:120,358,461...120,374,805
|
|
G |
H |
HGS |
hepatocyte growth factor-regulated tyrosine kinase substrate |
increases expression |
EXP |
Tacrolimus results in increased expression of HGS mRNA |
CTD |
PMID:29380240 |
|
NCBI chr17:81,684,011...81,702,121
Ensembl chr17:81,683,326...81,703,138
|
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G |
R |
Hk2 |
hexokinase 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of HK2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
|
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G |
M |
Hk2 |
hexokinase 2 |
increases expression |
EXP |
Tacrolimus results in increased expression of HK2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 6:82,702,004...82,751,435
Ensembl chr 6:82,702,006...82,751,435
|
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G |
H |
HK2 |
hexokinase 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of HK2 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 2:74,834,127...74,893,359
Ensembl chr 2:74,834,127...74,893,359
|
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G |
R |
Hk3 |
hexokinase 3 |
increases expression |
ISO |
Tacrolimus results in increased expression of HK3 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr17:9,596,950...9,614,847
Ensembl chr17:9,599,865...9,614,863
|
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G |
M |
Hk3 |
hexokinase 3 |
increases expression |
EXP |
Tacrolimus results in increased expression of HK3 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr13:55,153,798...55,169,233
Ensembl chr13:55,153,798...55,169,198
|
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G |
H |
HK3 |
hexokinase 3 |
increases expression |
ISO |
Tacrolimus results in increased expression of HK3 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 5:176,880,869...176,899,346
Ensembl chr 5:176,880,869...176,899,346
|
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G |
R |
Hmgcs2 |
3-hydroxy-3-methylglutaryl-CoA synthase 2 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of HMGCS2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
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G |
M |
Hmgcs2 |
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of HMGCS2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 3:98,187,747...98,218,054
Ensembl chr 3:98,187,751...98,218,054
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G |
H |
HMGCS2 |
3-hydroxy-3-methylglutaryl-CoA synthase 2 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of HMGCS2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905
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G |
R |
Hmox1 |
heme oxygenase 1 |
increases expression decreases expression multiple interactions |
ISO EXP |
Tacrolimus results in increased expression of HMOX1 mRNA; Tacrolimus results in increased expression of HMOX1 protein Tacrolimus results in decreased expression of HMOX1 protein MK0626 inhibits the reaction [Tacrolimus results in decreased expression of HMOX1 protein] |
CTD |
PMID:23958496 PMID:24959755 PMID:26260164 PMID:29362864 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
M |
Hmox1 |
heme oxygenase 1 |
increases expression decreases expression multiple interactions |
EXP ISO |
Tacrolimus results in increased expression of HMOX1 mRNA; Tacrolimus results in increased expression of HMOX1 protein Tacrolimus results in decreased expression of HMOX1 protein MK0626 inhibits the reaction [Tacrolimus results in decreased expression of HMOX1 protein] |
CTD |
PMID:23958496 PMID:24959755 PMID:26260164 PMID:29362864 |
|
NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
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G |
H |
HMOX1 |
heme oxygenase 1 |
increases expression decreases expression multiple interactions |
ISO EXP |
Tacrolimus results in increased expression of HMOX1 mRNA; Tacrolimus results in increased expression of HMOX1 protein Tacrolimus results in decreased expression of HMOX1 protein MK0626 inhibits the reaction [Tacrolimus results in decreased expression of HMOX1 protein] |
CTD |
PMID:23958496 PMID:24959755 PMID:26260164 PMID:29362864 |
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NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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G |
R |
Hnf1b |
HNF1 homeobox B |
decreases expression |
ISO |
Tacrolimus results in decreased expression of HNF1B mRNA |
CTD |
PMID:22416070 |
|
NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888
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G |
M |
Hnf1b |
HNF1 homeobox B |
decreases expression |
EXP |
Tacrolimus results in decreased expression of HNF1B mRNA |
CTD |
PMID:22416070 |
|
NCBI chr11:83,741,035...83,796,743
Ensembl chr11:83,740,889...83,796,645
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G |
H |
HNF1B |
HNF1 homeobox B |
decreases expression |
ISO |
Tacrolimus results in decreased expression of HNF1B mRNA |
CTD |
PMID:22416070 |
|
NCBI chr17:37,686,431...37,745,059
Ensembl chr17:37,686,431...37,745,059
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G |
R |
Hsdl2 |
hydroxysteroid dehydrogenase like 2 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of HSDL2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
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G |
M |
Hsdl2 |
hydroxysteroid dehydrogenase like 2 |
decreases expression |
EXP |
Tacrolimus results in decreased expression of HSDL2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 4:59,581,515...59,618,694
Ensembl chr 4:59,581,563...59,618,689
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G |
H |
HSDL2 |
hydroxysteroid dehydrogenase like 2 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of HSDL2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 9:112,380,108...112,472,405
Ensembl chr 9:112,380,080...112,472,405
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G |
R |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
ISO |
Tacrolimus results in increased expression of HSPA5 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
M |
Hspa5 |
heat shock protein 5 |
increases expression |
EXP |
Tacrolimus results in increased expression of HSPA5 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
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G |
H |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
ISO |
Tacrolimus results in increased expression of HSPA5 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
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G |
R |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
multiple interactions increases expression |
EXP |
Tacrolimus inhibits the reaction [Acrylamide results in decreased expression of HSPA8 protein] Tacrolimus results in increased expression of HSPA8 protein |
CTD |
PMID:15081597 |
|
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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G |
M |
Hspa8 |
heat shock protein 8 |
multiple interactions increases expression |
ISO |
Tacrolimus inhibits the reaction [Acrylamide results in decreased expression of HSPA8 protein] Tacrolimus results in increased expression of HSPA8 protein |
CTD |
PMID:15081597 |
|
NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383
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G |
H |
HSPA8 |
heat shock protein family A (Hsp70) member 8 |
multiple interactions increases expression |
ISO |
Tacrolimus inhibits the reaction [Acrylamide results in decreased expression of HSPA8 protein] Tacrolimus results in increased expression of HSPA8 protein |
CTD |
PMID:15081597 |
|
NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230
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G |
R |
Htr1a |
5-hydroxytryptamine receptor 1A |
decreases expression |
ISO |
Tacrolimus results in decreased expression of HTR1A protein |
CTD |
PMID:27606422 |
|
NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442
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G |
M |
Htr1a |
5-hydroxytryptamine (serotonin) receptor 1A |
decreases expression |
EXP |
Tacrolimus results in decreased expression of HTR1A protein |
CTD |
PMID:27606422 |
|
NCBI chr13:105,580,201...105,584,641
Ensembl chr13:105,580,147...105,584,630
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G |
H |
HTR1A |
5-hydroxytryptamine receptor 1A |
decreases expression |
ISO |
Tacrolimus results in decreased expression of HTR1A protein |
CTD |
PMID:27606422 |
|
NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,957,874...63,962,507
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G |
R |
Htr1b |
5-hydroxytryptamine receptor 1B |
decreases expression |
ISO |
Tacrolimus results in decreased expression of HTR1B protein |
CTD |
PMID:27606422 |
|
NCBI chr 8:82,513,572...82,534,892
Ensembl chr 8:82,517,360...82,534,549
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G |
M |
Htr1b |
5-hydroxytryptamine (serotonin) receptor 1B |
decreases expression |
EXP |
Tacrolimus results in decreased expression of HTR1B protein |
CTD |
PMID:27606422 |
|
NCBI chr 9:81,510,344...81,515,885
Ensembl chr 9:81,510,344...81,515,881
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G |
H |
HTR1B |
5-hydroxytryptamine receptor 1B |
decreases expression |
ISO |
Tacrolimus results in decreased expression of HTR1B protein |
CTD |
PMID:27606422 |
|
NCBI chr 6:77,460,924...77,463,491
Ensembl chr 6:77,460,924...77,463,491
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G |
R |
Icam1 |
intercellular adhesion molecule 1 |
decreases expression increases expression |
EXP ISO |
Tacrolimus results in decreased expression of ICAM1; Tacrolimus results in decreased expression of ICAM1 protein Tacrolimus results in increased expression of ICAM1 mRNA |
CTD |
PMID:9794552 PMID:10385251 PMID:23958496 |
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
M |
Icam1 |
intercellular adhesion molecule 1 |
decreases expression increases expression |
ISO EXP |
Tacrolimus results in decreased expression of ICAM1; Tacrolimus results in decreased expression of ICAM1 protein Tacrolimus results in increased expression of ICAM1 mRNA |
CTD |
PMID:9794552 PMID:10385251 PMID:23958496 |
|
NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
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G |
H |
ICAM1 |
intercellular adhesion molecule 1 |
decreases expression increases expression |
ISO |
Tacrolimus results in decreased expression of ICAM1; Tacrolimus results in decreased expression of ICAM1 protein Tacrolimus results in increased expression of ICAM1 mRNA |
CTD |
PMID:9794552 PMID:10385251 PMID:23958496 |
|
NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
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G |
R |
Id1 |
inhibitor of DNA binding 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of ID1 mRNA |
CTD |
PMID:25270620 PMID:29362864 |
|
NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
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G |
M |
Id1 |
inhibitor of DNA binding 1, HLH protein |
increases expression |
EXP |
Tacrolimus results in increased expression of ID1 mRNA |
CTD |
PMID:25270620 PMID:29362864 |
|
NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330
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G |
H |
ID1 |
inhibitor of DNA binding 1 |
increases expression |
ISO |
Tacrolimus results in increased expression of ID1 mRNA |
CTD |
PMID:25270620 PMID:29362864 |
|
NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,605,283...31,606,515
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G |
R |
Id2 |
inhibitor of DNA binding 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of ID2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
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G |
M |
Id2 |
inhibitor of DNA binding 2 |
increases expression |
EXP |
Tacrolimus results in increased expression of ID2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139
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G |
H |
ID2 |
inhibitor of DNA binding 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of ID2 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461
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G |
R |
Id3 |
inhibitor of DNA binding 3 |
increases expression |
ISO |
Tacrolimus results in increased expression of ID3 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
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G |
M |
Id3 |
inhibitor of DNA binding 3 |
increases expression |
EXP |
Tacrolimus results in increased expression of ID3 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066
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G |
H |
ID3 |
inhibitor of DNA binding 3 |
increases expression |
ISO |
Tacrolimus results in increased expression of ID3 mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 1:23,557,926...23,559,501
Ensembl chr 1:23,557,926...23,559,501
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G |
R |
Id4 |
inhibitor of DNA binding 4 |
increases expression |
ISO |
Tacrolimus results in increased expression of ID4 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470
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G |
M |
Id4 |
inhibitor of DNA binding 4 |
increases expression |
EXP |
Tacrolimus results in increased expression of ID4 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr13:48,414,592...48,419,504
Ensembl chr13:48,414,704...48,419,502
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G |
H |
ID4 |
inhibitor of DNA binding 4 |
increases expression |
ISO |
Tacrolimus results in increased expression of ID4 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr 6:19,837,370...19,842,197
Ensembl chr 6:19,837,370...19,842,197
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G |
R |
Idi1 |
isopentenyl-diphosphate delta isomerase 1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of IDI1 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
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G |
M |
Idi1 |
isopentenyl-diphosphate delta isomerase |
decreases expression |
EXP |
Tacrolimus results in decreased expression of IDI1 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr13:8,935,642...8,942,432
Ensembl chr13:8,935,537...8,942,487
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G |
H |
IDI1 |
isopentenyl-diphosphate delta isomerase 1 |
decreases expression |
ISO |
Tacrolimus results in decreased expression of IDI1 mRNA |
CTD |
PMID:25270620 |
|
NCBI chr10:1,039,152...1,056,704
Ensembl chr10:1,039,152...1,049,119
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G |
M |
Ifi202b |
interferon activated gene 202B |
increases expression |
EXP |
Tacrolimus results in increased expression of IFI202B mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 1:173,790,135...173,810,410
Ensembl chr 1:173,790,134...173,810,310
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G |
H |
IFI27L2 |
interferon alpha inducible protein 27 like 2 |
increases expression |
ISO |
Tacrolimus results in increased expression of IFI27L2A mRNA |
CTD |
PMID:29362864 |
|
NCBI chr14:94,127,781...94,129,604
Ensembl chr14:94,127,779...94,130,253
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G |
M |
Ifi27l2a |
interferon, alpha-inducible protein 27 like 2A |
increases expression |
EXP |
Tacrolimus results in increased expression of IFI27L2A mRNA |
CTD |
PMID:29362864 |
|
NCBI chr12:103,400,132...103,409,939
Ensembl chr12:103,408,426...103,409,939
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G |
R |
Ifi27l2b |
interferon, alpha-inducible protein 27 like 2B |
increases expression |
ISO |
Tacrolimus results in increased expression of IFI27L2A mRNA |
CTD |
PMID:29362864 |
|
NCBI chr 6:122,598,872...122,600,358
Ensembl chr 6:122,598,872...122,600,360
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G |
R |
Ifng |
interferon gamma |
multiple interactions decreases expression decreases secretion |
ISO EXP |
[Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IFNG protein]; Tacrolimus inhibits the reaction [enterotoxin A, Staphylococcal results in increased expression of IFNG protein]; Tacrolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IFNG mRNA] Tacrolimus results in decreased expression of IFNG protein Tacrolimus results in decreased expression of IFNG mRNA; Tacrolimus results in decreased expression of IFNG protein [Tacrolimus co-treated with TAK 779] results in decreased expression of IFNG protein Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in decreased expression of BCL2 protein]; Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BAX protein]; Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TRP53 protein] Tacrolimus results in decreased secretion of IFNG protein |
CTD |
PMID:1371491 PMID:8986461 PMID:10205001 PMID:11407316 PMID:11692113 PMID:16368244 PMID:20967261 PMID:21515370 PMID:24603311 PMID:29594315 More...
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
|
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G |
M |
Ifng |
interferon gamma |
multiple interactions decreases expression decreases secretion |
ISO EXP |
[Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IFNG protein]; Tacrolimus inhibits the reaction [enterotoxin A, Staphylococcal results in increased expression of IFNG protein]; Tacrolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IFNG mRNA] Tacrolimus results in decreased expression of IFNG protein Tacrolimus results in decreased expression of IFNG mRNA; Tacrolimus results in decreased expression of IFNG protein [Tacrolimus co-treated with TAK 779] results in decreased expression of IFNG protein Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in decreased expression of BCL2 protein]; Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BAX protein]; Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TRP53 protein] Tacrolimus results in decreased secretion of IFNG protein |
CTD |
PMID:1371491 PMID:8986461 PMID:10205001 PMID:11407316 PMID:11692113 PMID:16368244 PMID:20967261 PMID:21515370 PMID:24603311 PMID:29594315 More...
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|
NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
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G |
H |
IFNG |
interferon gamma |
multiple interactions decreases expression decreases secretion |
EXP ISO |
[Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IFNG protein]; Tacrolimus inhibits the reaction [enterotoxin A, Staphylococcal results in increased expression of IFNG protein]; Tacrolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IFNG mRNA] Tacrolimus results in decreased expression of IFNG protein Tacrolimus results in decreased expression of IFNG mRNA; Tacrolimus results in decreased expression of IFNG protein [Tacrolimus co-treated with TAK 779] results in decreased expression of IFNG protein Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in decreased expression of BCL2 protein]; Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BAX protein]; Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TRP53 protein] Tacrolimus results in decreased secretion of IFNG protein |
CTD |
PMID:1371491 PMID:8986461 PMID:10205001 PMID:11407316 PMID:11692113 PMID:16368244 PMID:20967261 PMID:21515370 PMID:24603311 PMID:29594315 More...
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NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
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G |
R |
Igf1 |
insulin-like growth factor 1 |
increases response to substance |
EXP |
IGF1 protein results in increased susceptibility to Tacrolimus |
CTD |
PMID:12826230 |
|
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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G |
M |
Igf1 |
insulin-like growth factor 1 |
increases response to substance |
ISO |
IGF1 protein results in increased susceptibility to Tacrolimus |
CTD |
PMID:12826230 |
|
NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
|
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G |
H |
IGF1 |
insulin like growth factor 1 |
increases response to substance |
ISO |
IGF1 protein results in increased susceptibility to Tacrolimus |
CTD |
PMID:12826230 |
|
NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744
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G |
R |
Igfbp1 |
insulin-like growth factor binding protein 1 |
decreases expression increases expression |
EXP |
Tacrolimus results in decreased expression of IGFBP1 mRNA Tacrolimus results in increased expression of IGFBP1 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
|
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G |
M |
Igfbp1 |
insulin-like growth factor binding protein 1 |
decreases expression increases expression |
ISO |
Tacrolimus results in decreased expression of IGFBP1 mRNA Tacrolimus results in increased expression of IGFBP1 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr11:7,147,787...7,152,546
Ensembl chr11:7,147,782...7,152,546
|
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G |
H |
IGFBP1 |
insulin like growth factor binding protein 1 |
decreases expression increases expression |
ISO |
Tacrolimus results in decreased expression of IGFBP1 mRNA Tacrolimus results in increased expression of IGFBP1 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660
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G |
R |
Igfbp5 |
insulin-like growth factor binding protein 5 |
increases expression |
EXP |
Tacrolimus results in increased expression of IGFBP5 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
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G |
M |
Igfbp5 |
insulin-like growth factor binding protein 5 |
increases expression |
ISO |
Tacrolimus results in increased expression of IGFBP5 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 1:72,897,224...72,914,024
Ensembl chr 1:72,897,091...72,914,043
|
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G |
H |
IGFBP5 |
insulin like growth factor binding protein 5 |
increases expression |
ISO |
Tacrolimus results in increased expression of IGFBP5 mRNA |
CTD |
PMID:21865292 |
|
NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549
|
|
G |
R |
Il15ra |
interleukin 15 receptor subunit alpha |
increases expression |
ISO |
Tacrolimus results in increased expression of IL15RA mRNA |
CTD |
PMID:23958496 |
|
NCBI chr17:66,802,300...66,831,973
Ensembl chr17:66,802,334...66,832,278
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G |
M |
Il15ra |
interleukin 15 receptor, alpha chain |
increases expression |
EXP |
Tacrolimus results in increased expression of IL15RA mRNA |
CTD |
PMID:23958496 |
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NCBI chr 2:11,709,992...11,738,796
Ensembl chr 2:11,710,101...11,739,128
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G |
H |
IL15RA |
interleukin 15 receptor subunit alpha |
increases expression |
ISO |
Tacrolimus results in increased expression of IL15RA mRNA |
CTD |
PMID:23958496 |
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NCBI chr10:5,948,900...5,978,741
Ensembl chr10:5,943,639...5,978,187
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G |
R |
Il17ra |
interleukin 17 receptor A |
increases expression |
ISO |
Tacrolimus results in increased expression of IL17RA mRNA |
CTD |
PMID:23958496 |
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NCBI chr 4:153,667,534...153,690,174
Ensembl chr 4:153,667,534...153,690,174
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G |
M |
Il17ra |
interleukin 17 receptor A |
increases expression |
EXP |
Tacrolimus results in increased expression of IL17RA mRNA |
CTD |
PMID:23958496 |
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NCBI chr 6:120,440,143...120,460,692
Ensembl chr 6:120,440,208...120,464,520
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G |
H |
IL17RA |
interleukin 17 receptor A |
increases expression |
ISO |
Tacrolimus results in increased expression of IL17RA mRNA |
CTD |
PMID:23958496 |
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NCBI chr22:17,085,000...17,115,693
Ensembl chr22:17,084,954...17,115,693
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G |
R |
Il1b |
interleukin 1 beta |
increases expression |
ISO |
Tacrolimus results in increased expression of IL1B mRNA |
CTD |
PMID:29594315 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
M |
Il1b |
interleukin 1 beta |
increases expression |
ISO |
Tacrolimus results in increased expression of IL1B mRNA |
CTD |
PMID:29594315 |
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NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
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G |
H |
IL1B |
interleukin 1 beta |
increases expression |
EXP |
Tacrolimus results in increased expression of IL1B mRNA |
CTD |
PMID:29594315 |
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NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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G |
R |
Il1rn |
interleukin 1 receptor antagonist |
increases expression |
ISO |
Tacrolimus results in increased expression of IL1RN mRNA |
CTD |
PMID:23958496 |
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NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
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G |
M |
Il1rn |
interleukin 1 receptor antagonist |
increases expression |
EXP |
Tacrolimus results in increased expression of IL1RN mRNA |
CTD |
PMID:23958496 |
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NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
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G |
H |
IL1RN |
interleukin 1 receptor antagonist |
increases expression |
ISO |
Tacrolimus results in increased expression of IL1RN mRNA |
CTD |
PMID:23958496 |
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NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016
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G |
R |
Il2 |
interleukin 2 |
multiple interactions decreases expression |
ISO EXP |
[Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 protein]; Tacrolimus inhibits the reaction [CD2 protein results in increased expression of IL2 protein]; Tacrolimus inhibits the reaction [enterotoxin A, Staphylococcal results in increased expression of IL2 protein]; Tacrolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Tacrolimus inhibits the reaction [Zinc Sulfate inhibits the reaction [Mitogens results in increased expression of IL2 mRNA]] Tacrolimus results in decreased expression of IL2 mRNA; Tacrolimus results in decreased expression of IL2 protein Tacrolimus affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL2 protein]; Tacrolimus inhibits the reaction [Sirolimus inhibits the reaction [IL2 protein results in increased phosphorylation of RPS6 protein]] |
CTD |
PMID:1371491 PMID:1614535 PMID:1701765 PMID:1705513 PMID:8986461 PMID:11407316 PMID:12126653 PMID:16055081 PMID:24603311 PMID:25770929 PMID:29594315 More...
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
M |
Il2 |
interleukin 2 |
multiple interactions decreases expression |
ISO EXP |
[Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 protein]; Tacrolimus inhibits the reaction [CD2 protein results in increased expression of IL2 protein]; Tacrolimus inhibits the reaction [enterotoxin A, Staphylococcal results in increased expression of IL2 protein]; Tacrolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Tacrolimus inhibits the reaction [Zinc Sulfate inhibits the reaction [Mitogens results in increased expression of IL2 mRNA]] Tacrolimus results in decreased expression of IL2 mRNA; Tacrolimus results in decreased expression of IL2 protein Tacrolimus affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL2 protein]; Tacrolimus inhibits the reaction [Sirolimus inhibits the reaction [IL2 protein results in increased phosphorylation of RPS6 protein]] |
CTD |
PMID:1371491 PMID:1614535 PMID:1701765 PMID:1705513 PMID:8986461 PMID:11407316 PMID:12126653 PMID:16055081 PMID:24603311 PMID:25770929 PMID:29594315 More...
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NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
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G |
H |
IL2 |
interleukin 2 |
multiple interactions decreases expression |
EXP ISO |
[Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 protein]; Tacrolimus inhibits the reaction [CD2 protein results in increased expression of IL2 protein]; Tacrolimus inhibits the reaction [enterotoxin A, Staphylococcal results in increased expression of IL2 protein]; Tacrolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Tacrolimus inhibits the reaction [Zinc Sulfate inhibits the reaction [Mitogens results in increased expression of IL2 mRNA]] Tacrolimus results in decreased expression of IL2 mRNA; Tacrolimus results in decreased expression of IL2 protein Tacrolimus affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL2 protein]; Tacrolimus inhibits the reaction [Sirolimus inhibits the reaction [IL2 protein results in increased phosphorylation of RPS6 protein]] |
CTD |
PMID:1371491 PMID:1614535 PMID:1701765 PMID:1705513 PMID:8986461 PMID:11407316 PMID:12126653 PMID:16055081 PMID:24603311 PMID:25770929 PMID:29594315 More...
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NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
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G |
R |
Il23a |
interleukin 23 subunit alpha |
increases expression |
ISO |
Tacrolimus results in increased expression of IL23A mRNA |
CTD |
PMID:25270620 |
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NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
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G |
M |
Il23a |
interleukin 23, alpha subunit p19 |
increases expression |
EXP |
Tacrolimus results in increased expression of IL23A mRNA |
CTD |
PMID:25270620 |
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NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621
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G |
H |
IL23A |
interleukin 23 subunit alpha |
increases expression |
ISO |
Tacrolimus results in increased expression of IL23A mRNA |
CTD |
PMID:25270620 |
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NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410
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G |
R |
Il2ra |
interleukin 2 receptor subunit alpha |
decreases expression |
ISO |
Tacrolimus results in decreased expression of IL2RA protein |
CTD |
PMID:1701765 |
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NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
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G |
M |
Il2ra |
interleukin 2 receptor, alpha chain |
decreases expression |
EXP |
Tacrolimus results in decreased expression of IL2RA protein |
CTD |
PMID:1701765 |
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NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004
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G |
H |
IL2RA |
interleukin 2 receptor subunit alpha |
decreases expression |
ISO |
Tacrolimus results in decreased expression of IL2RA protein |
CTD |
PMID:1701765 |
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NCBI chr10:6,010,689...6,062,367
Ensembl chr10:6,010,689...6,062,370
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G |
R |
Il3 |
interleukin 3 |
decreases expression multiple interactions |
ISO |
Tacrolimus results in decreased expression of IL3 protein Sirolimus inhibits the reaction [Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL3 protein]]; Tacrolimus inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL3 protein] |
CTD |
PMID:1376361 PMID:11407316 |
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NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
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G |
M |
Il3 |
interleukin 3 |
decreases expression multiple interactions |
ISO EXP |
Tacrolimus results in decreased expression of IL3 protein Sirolimus inhibits the reaction [Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL3 protein]]; Tacrolimus inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL3 protein] |
CTD |
PMID:1376361 PMID:11407316 |
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NCBI chr11:54,155,911...54,158,105
Ensembl chr11:54,156,129...54,158,103
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G |
H |
IL3 |
interleukin 3 |
decreases expression multiple interactions |
EXP ISO |
Tacrolimus results in decreased expression of IL3 protein Sirolimus inhibits the reaction [Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL3 protein]]; Tacrolimus inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL3 protein] |
CTD |
PMID:1376361 PMID:11407316 |
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NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204
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G |
R |
Il4 |
interleukin 4 |
multiple interactions decreases expression |
ISO EXP |
Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein] Tacrolimus results in decreased expression of IL4 mRNA; Tacrolimus results in decreased expression of IL4 protein Tacrolimus inhibits the reaction [bisphenol A promotes the reaction [NFATC3 protein binds to IL4 promoter]]; Tacrolimus inhibits the reaction [bisphenol A results in increased expression of IL4 protein]; Tacrolimus inhibits the reaction [nonylphenol promotes the reaction [NFATC3 protein binds to IL4 promoter]]; Tacrolimus inhibits the reaction [nonylphenol results in increased expression of IL4 protein] |
CTD |
PMID:1371491 PMID:10685002 PMID:11407316 PMID:12709020 PMID:16368244 |
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
M |
Il4 |
interleukin 4 |
multiple interactions decreases expression |
ISO EXP |
Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein] Tacrolimus results in decreased expression of IL | |