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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fondaparinux
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Accession:CHEBI:61033 term browser browse the term
Definition:A synthetic pentasaccharide which, apart from the O-methyl group at the reducing end of the molecule, consists of monomeric sugar units which are identical to a sequence of five monomeric sugar units that can be isolated after either chemical or enzymatic cleavage of the polymeric glycosaminoglycans heparin and heparan sulfate.
Synonyms:exact_synonym: methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl-(1->4)-beta-D-glucopyranuronosyl-(1->4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl-(1->4)-2-O-sulfo-alpha-L-idopyranuronosyl-(1->4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside
 related_synonym: Formula=C31H53N3O49S8;   InChI=1S/C31H53N3O49S8/c1-69-27-9(33-85(48,49)50)13(37)17(6(74-27)3-71-88(57,58)59)76-31-22(83-91(66,67)68)16(40)21(24(81-31)26(43)44)79-29-10(34-86(51,52)53)19(82-90(63,64)65)18(7(75-29)4-72-89(60,61)62)77-30-15(39)14(38)20(23(80-30)25(41)42)78-28-8(32-84(45,46)47)12(36)11(35)5(73-28)2-70-87(54,55)56/h5-24,27-40H,2-4H2,1H3,(H,41,42)(H,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)/t5-,6-,7-,8-,9-,10-,11-,12-,13-,14-,15-,16+,17-,18-,19-,20+,21+,22-,23+,24-,27+,28-,29-,30-,31-/m1/s1;   InChIKey=KANJSNBRCNMZMV-ABRZTLGGSA-N;   Natural heparin pentasaccharide;   SMILES=CO[C@H]1O[C@H](COS(O)(=O)=O)[C@@H](O[C@@H]2O[C@H]([C@@H](O[C@H]3O[C@H](COS(O)(=O)=O)[C@@H](O[C@@H]4O[C@@H]([C@@H](O[C@H]5O[C@H](COS(O)(=O)=O)[C@@H](O)[C@H](O)[C@H]5NS(O)(=O)=O)[C@H](O)[C@H]4O)C(O)=O)[C@H](OS(O)(=O)=O)[C@H]3NS(O)(=O)=O)[C@H](O)[C@H]2OS(O)(=O)=O)C(O)=O)[C@H](O)[C@H]1NS(O)(=O)=O;   fondaparin
 alt_id: CHEBI:44566
 xref: CAS:104993-28-4;   Drug_Central:1236
 xref_mesh: MESH:C438268
 xref: PDBeChem:NTO;   PMID:29531454;   PMID:30169652;   PMID:30656269;   PMID:31030756;   PMID:31251320;   PMID:31549765;   PMID:31782283;   PPR:PPR103739;   Reaxys:9381701;   Wikipedia:Fondaparinux
 cyclic_relationship: is_conjugate_acid_of CHEBI:61038



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fondaparinux term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F10 coagulation factor X decreases activity ISO fondaparinux results in decreased activity of F10 protein CTD PMID:16084352 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
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  CHEBI ontology 19810
    role 19759
      application 19468
        pharmaceutical 19316
          drug 19316
            hematologic agent 4406
              anticoagulant 4187
                fondaparinux 1
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Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19809
      composite particle 19809
        hadron 19809
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19706
                    p-block element atom 19706
                      chalcogen 19458
                        oxygen atom 19434
                          oxygen molecular entity 19434
                            hydroxides 19171
                              oxoacid 18489
                                chalcogen oxoacid 11492
                                  sulfur oxoacid 11100
                                    sulfuric acid 8013
                                      sulfuric acid derivative 8013
                                        sulfates 8009
                                          organic sulfate 1947
                                            carbohydrate sulfate 1421
                                              oligosaccharide sulfate 2
                                                normethylfondaparinux 1
                                                  fondaparinux 1
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