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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(2R,2(1)S)8-ethenyl-2(1),2(2)-bis(methoxycarbonyl)-13-(3-methoxy-3-oxopropyl)-2,7,12,18-tetramethyl-2,2(1)-dihydrobenzo[b]porphyrin-17-propanoic acid
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Accession:CHEBI:60778 term browser browse the term
Definition:The 2(1),2(2),13-trimethyl ester of (2R,2(1)S)-2(1),2(2)-dicarboxy-8-ethenyl-2,7,12,18-tetramethyl-2,2(1)-dihydrobenzo[b]porphyrin-13,17-dipropanoic acid.
Synonyms:related_synonym: (4S,4aR)-18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-23H,25H-benzo[b]porphine-9,13-dipropanoic acid 13-methyl ester;   3-[(1Z,6Z,12Z,17Z,23S,24R)-14-ethenyl-22,23-bis(methoxycarbonyl)-9-(3-methoxy-3-oxopropyl)-4,10,15,24-tetramethyl-25,26,27,28-tetraazahexacyclo[16.6.1.1(3,6).1(8,11).1(13,16).0(19,24)]octacosa-1,3(28),4,6,8,10,12,14,16(26),17,19,21-dodecaen-5-yl]propanoic acid;   Formula=C41H42N4O8;   InChI=1S/C41H42N4O8/c1-9-23-20(2)29-17-34-27-13-10-26(39(49)52-7)38(40(50)53-8)41(27,5)35(45-34)19-30-22(4)24(11-14-36(46)47)32(44-30)18-33-25(12-15-37(48)51-6)21(3)28(43-33)16-31(23)42-29/h9-10,13,16-19,38,43,45H,1,11-12,14-15H2,2-8H3,(H,46,47)/b31-16-,32-18-,34-17-,35-19-/t38-,41+/m0/s1;   InChIKey=MNCZEEFHIBYYSK-SUPIZNKRSA-N;   SMILES=COC(=O)CCc1c(C)c2cc3nc(cc4[nH]c(cc5nc(cc1[nH]2)c(CCC(O)=O)c5C)[C@]1(C)[C@H](C(=O)OC)C(=CC=C41)C(=O)OC)c(C)c3C=C
 cyclic_relationship: is_enantiomer_of CHEBI:60779


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verteporfin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl4 acyl-CoA synthetase long-chain family member 4 multiple interactions EXP Verteporfin inhibits the reaction [Melatonin inhibits the reaction [Doxorubicin results in increased expression of ACSL4 protein]] CTD PMID:35093381 NCBI chr  X:110,739,633...110,803,416
Ensembl chr  X:110,739,648...110,803,261 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO Verteporfin inhibits the reaction [calcipotriene promotes the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA]] CTD PMID:38992766 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Amotl1 angiomotin-like 1 multiple interactions
decreases response to substance 		ISO Verteporfin inhibits the reaction [AMOTL1 protein results in increased activity of YAP1 protein]
Verteporfin results in decreased susceptibility to AMOTL1 protein 		CTD PMID:34480788 NCBI chr 8:19,630,139...19,749,027
Ensembl chr 8:19,634,510...19,748,869 		JBrowse link
G Ankrd1 ankyrin repeat domain 1 multiple interactions
decreases expression 		ISO verteporfin inhibits the reaction [YAP1 protein results in increased expression of ANKRD1 mRNA]
verteporfin results in decreased expression of ANKRD1 mRNA
[calcipotriene co-treated with Verteporfin] promotes the reaction [Carbon Tetrachloride results in increased expression of ANKRD1 mRNA]; Verteporfin inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of ANKRD1 mRNA]; Verteporfin promotes the reaction [Carbon Tetrachloride results in increased expression of ANKRD1 mRNA] 		CTD PMID:29725256 PMID:29893953 PMID:38992766 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:243,228,448...243,263,751 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP Verteporfin inhibits the reaction [Melatonin inhibits the reaction [Doxorubicin results in increased expression of BAX protein]] CTD PMID:35093381 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP Verteporfin inhibits the reaction [Melatonin inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]] CTD PMID:35093381 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO Verteporfin inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of BIRC5 mRNA] CTD PMID:29893953 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155 		JBrowse link
G Casp9 caspase 9 multiple interactions EXP Verteporfin inhibits the reaction [Melatonin inhibits the reaction [Doxorubicin results in decreased expression of and results in increased cleavage of CASP9 protein]] CTD PMID:35093381 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CCL2 protein] CTD PMID:31812773 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CCL5 protein] CTD PMID:31812773 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884 		JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions
decreases expression 		ISO Verteporfin inhibits the reaction [YAP1 protein results in increased expression of CCN1 mRNA]
Verteporfin results in decreased expression of CCN1 mRNA
Verteporfin inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CCN1 mRNA] 		CTD PMID:29725256 PMID:29893953 NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883 		JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression
multiple interactions 		ISO Verteporfin results in decreased expression of CCN2 mRNA
Verteporfin inhibits the reaction [YAP1 protein results in increased expression of CCN2 mRNA]
[calcipotriene co-treated with Verteporfin] promotes the reaction [Carbon Tetrachloride results in increased expression of CCN2 mRNA]; Verteporfin inhibits the reaction [[XMU-MP-1 co-treated with Cadmium Chloride] results in increased expression of CCN2 mRNA]; Verteporfin promotes the reaction [Carbon Tetrachloride results in increased expression of CCN2 mRNA] 		CTD PMID:29725256 PMID:35027733 PMID:38992766 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976 		JBrowse link
G Ccna2 cyclin A2 multiple interactions ISO Verteporfin inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CCNA2 mRNA] CTD PMID:29893953 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701 		JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO Verteporfin inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CCNB1 mRNA] CTD PMID:29893953 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225 		JBrowse link
G Cdc20 cell division cycle 20 multiple interactions ISO [Verteporfin co-treated with calcipotriene] inhibits the reaction [Carbon Tetrachloride results in increased expression of CDC20 mRNA]; Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of CDC20 mRNA] CTD PMID:38992766 NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:137,251,596...137,255,799 		JBrowse link
G Cdc6 cell division cycle 6 multiple interactions ISO Verteporfin inhibits the reaction [calcipotriene promotes the reaction [Carbon Tetrachloride results in increased expression of CDC6 mRNA]]; Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of CDC6 mRNA] CTD PMID:38992766 NCBI chr10:84,360,361...84,374,239
Ensembl chr10:84,360,381...84,374,241 		JBrowse link
G Cma1 chymase 1 multiple interactions ISO Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CMA1 protein] CTD PMID:31812773 NCBI chr15:33,387,351...33,390,133
Ensembl chr15:33,387,351...33,390,133 		JBrowse link
G Cnn2 calponin 2 multiple interactions ISO Verteporfin inhibits the reaction [calcipotriene promotes the reaction [Carbon Tetrachloride results in increased expression of CNN2 mRNA]]; Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of CNN2 mRNA] CTD PMID:38992766 NCBI chr 7:9,712,505...9,719,678
Ensembl chr 7:10,363,102...10,370,312 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO [calcipotriene co-treated with Verteporfin] inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]; Verteporfin inhibits the reaction [calcipotriene promotes the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]]; Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA] CTD PMID:38992766 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Csf3 colony stimulating factor 3 multiple interactions ISO Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CSF3 protein] CTD PMID:31812773 NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO Verteporfin inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CYP2B10 mRNA] CTD PMID:29893953 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 multiple interactions ISO Verteporfin inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CYP2C55 mRNA] CTD PMID:29893953 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:246,286,341...246,348,607 		JBrowse link
G Fundc1 FUN14 domain containing 1 multiple interactions EXP Verteporfin inhibits the reaction [Melatonin inhibits the reaction [Doxorubicin results in increased expression of FUNDC1 protein]] CTD PMID:35093381 NCBI chr  X:5,083,635...5,100,293
Ensembl chr  X:7,666,759...7,683,441 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO Verteporfin results in decreased expression of GCLC protein CTD PMID:37832483 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO Verteporfin inhibits the reaction [calcipotriene promotes the reaction [Carbon Tetrachloride results in increased expression of GPT protein]]; Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of GPT protein] CTD PMID:38992766 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions
decreases expression 		EXP
ISO 		Verteporfin inhibits the reaction [Melatonin inhibits the reaction [Doxorubicin results in decreased expression of GPX4 protein]]
Verteporfin results in decreased expression of GPX4 protein 		CTD PMID:35093381 PMID:37832483 NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629 		JBrowse link
G Gsr glutathione-disulfide reductase decreases expression ISO Verteporfin results in decreased expression of GSR protein CTD PMID:37832483 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394 		JBrowse link
G Hmmr hyaluronan-mediated motility receptor multiple interactions ISO Verteporfin inhibits the reaction [calcipotriene promotes the reaction [Carbon Tetrachloride results in increased expression of HMMR mRNA]]; Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of HMMR mRNA] CTD PMID:38992766 NCBI chr10:25,635,249...25,665,389
Ensembl chr10:25,635,915...25,665,390 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO verteporfin results in increased expression of HMOX1 protein CTD PMID:16462769 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Il11 interleukin 11 multiple interactions ISO Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL11 mRNA]; Verteporfin promotes the reaction [calcipotriene inhibits the reaction [Carbon Tetrachloride results in increased expression of IL11 mRNA]] CTD PMID:38992766 NCBI chr 1:78,098,622...78,104,915
Ensembl chr 1:78,096,930...78,104,915 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO [EVP 4593 co-treated with Verteporfin] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]; Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]
Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]; Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein] 		CTD PMID:31812773 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Iqgap3 IQ motif containing GTPase activating protein 3 multiple interactions ISO [Verteporfin co-treated with calcipotriene] inhibits the reaction [Carbon Tetrachloride results in increased expression of IQGAP3 mRNA]; Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of IQGAP3 mRNA] CTD PMID:38992766 NCBI chr 2:175,840,001...175,881,799
Ensembl chr 2:175,839,949...175,881,797 		JBrowse link
G Jak1 Janus kinase 1 multiple interactions
decreases expression 		ISO [Verteporfin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in decreased expression of JAK1 protein
Verteporfin results in decreased expression of JAK1 protein 		CTD PMID:31812773 NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758 		JBrowse link
G Jak2 Janus kinase 2 decreases expression
multiple interactions 		ISO Verteporfin results in decreased expression of JAK2 protein
[Verteporfin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in decreased expression of JAK2 protein 		CTD PMID:31812773 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762 		JBrowse link
G Mcm2 minichromosome maintenance complex component 2 multiple interactions ISO Verteporfin inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of MCM2 mRNA] CTD PMID:29893953 NCBI chr 4:122,903,679...122,918,205
Ensembl chr 4:122,903,682...122,918,094 		JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO Verteporfin inhibits the reaction [[calcipotriene co-treated with Carbon Tetrachloride] results in increased expression of MKI67 mRNA]; Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of MKI67 mRNA]; Verteporfin inhibits the reaction [perfluorooctanoic acid results in increased expression of MKI67 protein] CTD PMID:36152675 PMID:38992766 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593 		JBrowse link
G Mt1a metallothionein 1A multiple interactions ISO [Verteporfin co-treated with XMU-MP-1] promotes the reaction [Cadmium Chloride results in increased expression of MT1 mRNA] CTD PMID:35027733 NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr  X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200 		JBrowse link
G Mt2 metallothionein 2 multiple interactions ISO [Verteporfin co-treated with XMU-MP-1] promotes the reaction [Cadmium Chloride results in increased expression of MT2 mRNA] CTD PMID:35027733 NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709 		JBrowse link
G Nppb natriuretic peptide B multiple interactions EXP Verteporfin inhibits the reaction [Melatonin inhibits the reaction [Doxorubicin results in increased expression of NPPB protein]] CTD PMID:35093381 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions EXP Verteporfin inhibits the reaction [Melatonin inhibits the reaction [Doxorubicin results in decreased expression of OPA1 protein]] CTD PMID:35093381 NCBI chr11:84,612,943...84,690,025
Ensembl chr11:84,615,340...84,689,955 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Verteporfin results in increased cleavage of PARP1 protein CTD PMID:31494105 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Rasal2 RAS protein activator like 2 multiple interactions ISO Verteporfin inhibits the reaction [RASAL2 protein results in increased activity of YAP1 protein] CTD PMID:34826200 NCBI chr13:71,808,740...72,102,723
Ensembl chr13:71,813,261...72,102,723 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [Verteporfin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in decreased expression of RELA protein; Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of and results in increased phosphorylation of RELA protein] CTD PMID:31812773 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 decreases expression
multiple interactions 		ISO Verteporfin results in decreased expression of STAT1 protein
Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of and results in increased phosphorylation of STAT1 protein] 		CTD PMID:31812773 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
decreases expression 		ISO Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of and results in increased phosphorylation of STAT3 protein]
Verteporfin results in decreased expression of STAT3 protein 		CTD PMID:31812773 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Tead1 TEA domain transcription factor 1 multiple interactions ISO Verteporfin inhibits the reaction [YAP1 protein binds to TEAD1 protein] CTD PMID:29893953 NCBI chr 1:176,227,175...176,445,122
Ensembl chr 1:176,227,175...176,438,198 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO [Verteporfin co-treated with Carbon Tetrachloride] results in increased expression of TIMP1 mRNA; Verteporfin inhibits the reaction [[calcipotriene co-treated with Carbon Tetrachloride] results in increased expression of TIMP1 mRNA] CTD PMID:38992766 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Verteporfin inhibits the reaction [[calcipotriene co-treated with Carbon Tetrachloride] results in increased expression of TNF mRNA]; Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]; Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]; Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]
[EVP 4593 co-treated with Verteporfin] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]; Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA] 		CTD PMID:31812773 PMID:38992766 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions ISO [Verteporfin co-treated with calcipotriene] inhibits the reaction [Carbon Tetrachloride results in increased expression of TOP2A mRNA]; Verteporfin inhibits the reaction [[calcipotriene co-treated with Carbon Tetrachloride] results in increased expression of TOP2A mRNA]; Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of TOP2A mRNA] CTD PMID:38992766 NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator multiple interactions
decreases expression
decreases activity 		ISO
EXP 		Verteporfin inhibits the reaction [AMOTL1 protein results in increased activity of YAP1 protein]; Verteporfin inhibits the reaction [RASAL2 protein results in increased activity of YAP1 protein]; Verteporfin inhibits the reaction [YAP1 protein results in increased expression of ANKRD1 mRNA]; Verteporfin inhibits the reaction [YAP1 protein results in increased expression of CCN1 mRNA]; Verteporfin inhibits the reaction [YAP1 protein results in increased expression of CCN2 mRNA]
Verteporfin inhibits the reaction [YAP1 protein binds to TEAD1 protein]
Verteporfin results in decreased expression of YAP1 protein
Verteporfin results in decreased activity of YAP1 protein
Verteporfin inhibits the reaction [Melatonin inhibits the reaction [Doxorubicin results in increased phosphorylation of YAP1 protein]] 		CTD PMID:29725256 PMID:29893953 PMID:31494105 PMID:34351699 PMID:34480788 More... NCBI chr 8:13,380,551...13,451,640
Ensembl chr 8:13,380,551...13,451,437 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      application 20621
        fuel 11499
          methanol 4014
            methyl ester 3961
              (2R,2(1)S)8-ethenyl-2(1),2(2)-bis(methoxycarbonyl)-13-(3-methoxy-3-oxopropyl)-2,7,12,18-tetramethyl-2,2(1)-dihydrobenzo[b]porphyrin-17-propanoic acid 50
                verteporfin 50
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            organic molecule 20654
                              organic cyclic compound 20404
                                organic heterocyclic compound 19388
                                  organonitrogen heterocyclic compound 18546
                                    polypyrrole 711
                                      tetrapyrrole 599
                                        cyclic tetrapyrrole 471
                                          porphyrins 389
                                            beta-substituted porphyrin 50
                                              (2R,2(1)S)-2(1),2(2)-dicarboxy-8-ethenyl-2,7,12,18-tetramethyl-2,2(1)-dihydrobenzo[b]porphyrin-13,17-dipropanoic acid 50
                                                (2R,2(1)S)8-ethenyl-2(1),2(2)-bis(methoxycarbonyl)-13-(3-methoxy-3-oxopropyl)-2,7,12,18-tetramethyl-2,2(1)-dihydrobenzo[b]porphyrin-17-propanoic acid 50
                                                  verteporfin 50
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