Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

go back to main search page
Accession:CHEBI:60762 term browser browse the term
Definition:An organochlorine compound consisting of uracil having an chloro substituent at the 5-position.
Synonyms:exact_synonym: 5-chloropyrimidine-2,4(1H,3H)-dione
 related_synonym: Formula=C4H3ClN2O2;   InChI=1S/C4H3ClN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9);   InChIKey=ZFTBZKVVGZNMJR-UHFFFAOYSA-N;   SMILES=Clc1c[nH]c(=O)[nH]c1=O
 xref: CAS:1820-81-1
 xref_mesh: MESH:C010889
 xref: PMID:10513989;   PMID:3007759;   PMID:3950402;   Reaxys:127173

show annotations for term's descendants           Sort by:
5-chlorouracil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Polb DNA polymerase beta affects metabolic processing ISO POLB protein affects the metabolism of 5-chlorouracil CTD PMID:20104909 NCBI chr16:74,237,001...74,260,272
Ensembl chr16:74,237,001...74,260,271
JBrowse link
G Smug1 single-strand-selective monofunctional uracil-DNA glycosylase 1 affects metabolic processing ISO SMUG1 protein affects the metabolism of 5-chlorouracil CTD PMID:20104909 NCBI chr 7:144,774,155...144,788,333
Ensembl chr 7:144,774,160...144,778,656
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      application 19391
        pro-agent 8829
          prodrug 8609
            uracil 5637
              5-chlorouracil 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic molecule 19486
                              organic cyclic compound 19282
                                organic heterocyclic compound 18407
                                  organic heteromonocyclic compound 16444
                                    diazines 12138
                                      pyrimidines 11955
                                        pyrimidine nucleobase 6082
                                          uracil 5637
                                            5-chlorouracil 2
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.