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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:5-chlorouracil
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Accession:CHEBI:60762 term browser browse the term
Definition:An organochlorine compound consisting of uracil having an chloro substituent at the 5-position.
Synonyms:exact_synonym: 5-chloropyrimidine-2,4(1H,3H)-dione
 related_synonym: Formula=C4H3ClN2O2;   InChI=1S/C4H3ClN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9);   InChIKey=ZFTBZKVVGZNMJR-UHFFFAOYSA-N;   SMILES=Clc1c[nH]c(=O)[nH]c1=O
 xref: CAS:1820-81-1
 xref_mesh: MESH:C010889
 xref: PMID:10513989;   PMID:3007759;   PMID:3950402;   Reaxys:127173


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5-chlorouracil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Polb DNA polymerase beta affects metabolic processing ISO POLB protein affects the metabolism of 5-chlorouracil CTD PMID:20104909 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812
JBrowse link
G Smug1 single-strand-selective monofunctional uracil-DNA glycosylase 1 affects metabolic processing ISO SMUG1 protein affects the metabolism of 5-chlorouracil CTD PMID:20104909 NCBI chr 7:134,288,565...134,302,179
Ensembl chr 7:134,287,675...134,297,226
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      application 19481
        pro-agent 10099
          prodrug 9902
            uracil 5677
              5-chlorouracil 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic molecule 19569
                              organic cyclic compound 19360
                                organic heterocyclic compound 18591
                                  organic heteromonocyclic compound 17084
                                    diazines 12328
                                      pyrimidines 12157
                                        pyrimidine nucleobase 6220
                                          uracil 5677
                                            5-chlorouracil 2
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