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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:isotretinoin
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Accession:CHEBI:6067 term browser browse the term
Definition:A retinoic acid that is all-trans-retinoic acid in which the double bond which is alpha,beta- to the carboxy group is isomerised to Z configuration. A synthetic retinoid, it is used for the treatment of severe cases of acne and other skin diseases.
Synonyms:exact_synonym: (2Z,4E6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
 related_synonym: (7E,9E,11E,13Z)-retinoic acid;   13-RA;   13-cis-Vitamin A acid;   13-cis-retinoic acid;   Accutane;   Amnesteem;   Claravis;   Formula=C20H28O2;   InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14-;   InChIKey=SHGAZHPCJJPHSC-XFYACQKRSA-N;   Neovitamin A acid;   SMILES=CC(\\C=C\\C1=C(C)CCCC1(C)C)=C/C=C/C(C)=C\\C(O)=O;   cis-RA;   isotretinoina;   isotretinoine;   isotretinoino;   isotretinoinum
 xref: Beilstein:1885770;   CAS:4759-48-2;   DrugBank:DB00982;   Drug_Central:1508;   HMDB:HMDB0006219;   KEGG:D00348;   LIPID_MAPS_instance:LMPR01090021
 xref_mesh: MESH:D015474
 xref: PMID:11606947;   PMID:11866680;   PMID:15304471;   PMID:18077132;   PMID:18788179;   PMID:19568610;   PMID:20482692;   PMID:23676507;   PMID:9807973;   Patent:EP111325;   Patent:US4556518;   Reaxys:1885770;   Wikipedia:Isotretinoin
 cyclic_relationship: is_conjugate_acid_of CHEBI:169952


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isotretinoin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin increases expression ISO Isotretinoin results in increased expression of A2M mRNA CTD PMID:20436886 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Aacs acetoacetyl-CoA synthetase decreases expression ISO Isotretinoin results in decreased expression of AACS mRNA CTD PMID:20436886 NCBI chr12:31,113,098...31,156,411
Ensembl chr12:31,113,098...31,160,954 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 increases expression EXP Isotretinoin results in increased expression of ABCA1 protein CTD PMID:17478430 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO [vorinostat co-treated with Isotretinoin] results in increased expression of ABCB1 mRNA CTD PMID:18769122 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 increases expression EXP Isotretinoin results in increased expression of ABCG1 protein CTD PMID:17478430 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948 		JBrowse link
G Abhd5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase decreases expression ISO Isotretinoin results in decreased expression of ABHD5 mRNA CTD PMID:20436886 NCBI chr 8:122,000,241...122,026,447
Ensembl chr 8:122,000,389...122,026,447 		JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A decreases expression ISO Isotretinoin results in decreased expression of ACAA1 mRNA CTD PMID:20436886 NCBI chr 8:119,079,401...119,088,624
Ensembl chr 8:119,079,775...119,088,624 		JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 decreases expression ISO Isotretinoin results in decreased expression of ACAA2 mRNA CTD PMID:20436886 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases expression ISO Isotretinoin results in decreased expression of ACACA mRNA CTD PMID:20436886 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acad8 acyl-CoA dehydrogenase family, member 8 decreases expression ISO Isotretinoin results in decreased expression of ACAD8 mRNA CTD PMID:20436886 NCBI chr 8:25,382,271...25,406,429
Ensembl chr 8:25,382,273...25,406,414 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases expression ISO Isotretinoin results in decreased expression of ACADM mRNA CTD PMID:20436886 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147 		JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain decreases expression ISO Isotretinoin results in decreased expression of ACADVL mRNA CTD PMID:20436886 NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 decreases expression ISO Isotretinoin results in decreased expression of ACAT2 mRNA CTD PMID:20436886 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821 		JBrowse link
G Acly ATP citrate lyase decreases expression ISO Isotretinoin results in decreased expression of ACLY mRNA CTD PMID:20436886 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320 		JBrowse link
G Aco1 aconitase 1 decreases expression ISO Isotretinoin results in decreased expression of ACO1 mRNA CTD PMID:20436886 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391 		JBrowse link
G Acot13 acyl-CoA thioesterase 13 decreases expression ISO Isotretinoin results in decreased expression of ACOT13 mRNA CTD PMID:20436886 NCBI chr17:40,240,378...40,252,851
Ensembl chr17:40,240,378...40,252,851 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 decreases expression ISO Isotretinoin results in decreased expression of ACOT2 mRNA CTD PMID:20436886 NCBI chr 6:103,611,744...103,619,404
Ensembl chr 6:103,611,544...103,619,245 		JBrowse link
G Acox2 acyl-CoA oxidase 2 decreases expression ISO Isotretinoin results in decreased expression of ACOX2 mRNA CTD PMID:20436886 NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160 		JBrowse link
G Acp6 acid phosphatase 6, lysophosphatidic decreases expression ISO Isotretinoin results in decreased expression of ACP6 mRNA CTD PMID:20436886 NCBI chr 2:184,711,975...184,733,067
Ensembl chr 2:184,711,619...184,733,017 		JBrowse link
G Acsbg1 acyl-CoA synthetase bubblegum family member 1 decreases expression ISO Isotretinoin results in decreased expression of ACSBG1 mRNA CTD PMID:20436886 NCBI chr 8:54,991,294...55,047,276
Ensembl chr 8:54,991,296...55,047,391 		JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression ISO Isotretinoin results in decreased expression of ACSL3 mRNA CTD PMID:20436886 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627 		JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression ISO Isotretinoin results in decreased expression of ACSL5 mRNA CTD PMID:20436886 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607 		JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 decreases expression ISO Isotretinoin results in decreased expression of SAH mRNA CTD PMID:20436886 NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184 		JBrowse link
G Acy1 aminoacylase 1 decreases expression ISO Isotretinoin results in decreased expression of ACY1 mRNA CTD PMID:20436886 NCBI chr 8:107,072,354...107,077,756
Ensembl chr 8:107,072,358...107,077,682 		JBrowse link
G Adgra2 adhesion G protein-coupled receptor A2 increases expression ISO Isotretinoin results in increased expression of ADGRA2 mRNA CTD PMID:20436886 NCBI chr16:64,932,964...64,971,433
Ensembl chr16:64,933,315...64,971,483 		JBrowse link
G Adgre5 adhesion G protein-coupled receptor E5 increases expression ISO Isotretinoin results in increased expression of ADGRE5 mRNA CTD PMID:20436886 NCBI chr19:24,397,972...24,418,648
Ensembl chr19:24,398,689...24,418,638 		JBrowse link
G Adgrg2 adhesion G protein-coupled receptor G2 decreases expression ISO Isotretinoin results in decreased expression of ADGRG2 mRNA CTD PMID:20436886 NCBI chr  X:34,297,402...34,422,590
Ensembl chr  X:34,297,402...34,422,609 		JBrowse link
G Adra2a adrenoceptor alpha 2A increases expression ISO Isotretinoin results in increased expression of ADRA2A mRNA CTD PMID:20436886 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein decreases expression ISO Isotretinoin results in decreased expression of ADTRP mRNA CTD PMID:20436886 NCBI chr17:22,930,012...22,993,834
Ensembl chr17:22,930,740...22,993,826 		JBrowse link
G Aga aspartylglucosaminidase decreases expression ISO Isotretinoin results in decreased expression of AGA mRNA CTD PMID:20436886 NCBI chr16:38,504,661...38,516,607
Ensembl chr16:38,504,663...38,516,606 		JBrowse link
G Agpat3 1-acylglycerol-3-phosphate O-acyltransferase 3 decreases expression ISO Isotretinoin results in decreased expression of AGPAT3 mRNA CTD PMID:20436886 NCBI chr20:10,330,960...10,415,358
Ensembl chr20:10,384,507...10,415,358 		JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member decreases expression ISO Isotretinoin results in decreased expression of AGR2 mRNA CTD PMID:20436886 NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression EXP Isotretinoin results in increased expression of AGTR1 mRNA; Isotretinoin results in increased expression of AGTR1 protein CTD PMID:19212007 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Ahsp alpha hemoglobin stabilizing protein decreases expression ISO Isotretinoin results in decreased expression of AHSP mRNA CTD PMID:20436886 NCBI chr 1:182,879,901...182,885,508
Ensembl chr 1:182,880,076...182,885,506 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 decreases expression ISO Isotretinoin results in decreased expression of AIFM1 mRNA CTD PMID:20436886 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Aip aryl-hydrocarbon receptor-interacting protein decreases expression ISO Isotretinoin results in decreased expression of AIP mRNA CTD PMID:15982314 NCBI chr 1:201,407,287...201,419,220
Ensembl chr 1:201,407,288...201,419,122 		JBrowse link
G Akap11 A-kinase anchoring protein 11 increases expression ISO Isotretinoin results in increased expression of AKAP11 mRNA CTD PMID:20436886 NCBI chr15:53,911,635...53,956,138
Ensembl chr15:53,911,657...53,941,605 		JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 decreases expression ISO Isotretinoin results in decreased expression of AKR1A1 mRNA CTD PMID:20436886 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 decreases expression ISO Isotretinoin results in decreased expression of ALAS1 mRNA CTD PMID:20436886 NCBI chr 8:106,876,514...106,889,852
Ensembl chr 8:106,876,514...106,889,917 		JBrowse link
G Alb albumin decreases expression EXP Isotretinoin results in decreased expression of ALB protein CTD PMID:16092084 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Alcam activated leukocyte cell adhesion molecule decreases expression ISO Isotretinoin results in decreased expression of ALCAM mRNA CTD PMID:20436886 NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases expression ISO Isotretinoin results in decreased expression of ALDH1A2 mRNA CTD PMID:31711903 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Aldh3b2 aldehyde dehydrogenase 3 family, member B2 decreases expression ISO Isotretinoin results in decreased expression of ALDH3B2 mRNA CTD PMID:20436886 NCBI chr 1:201,250,260...201,264,699
Ensembl chr 1:201,253,157...201,264,705 		JBrowse link
G Aldh3b3 aldehyde dehydrogenase 3 family, member B3 decreases expression ISO Isotretinoin results in decreased expression of ALDH3B2 mRNA CTD PMID:20436886 NCBI chr 1:201,193,832...201,201,666
Ensembl chr 1:201,187,962...201,250,204 		JBrowse link
G Alg13 ALG13, UDP-N-acetylglucosaminyltransferase subunit decreases expression ISO Isotretinoin results in decreased expression of ALG13 mRNA CTD PMID:20436886 NCBI chr  X:107,885,039...107,906,264
Ensembl chr  X:107,885,064...107,893,002 		JBrowse link
G Alox15b arachidonate 15-lipoxygenase, type B decreases expression ISO Isotretinoin results in decreased expression of ALOX15B mRNA CTD PMID:20436886 NCBI chr10:53,892,496...53,901,812
Ensembl chr10:53,892,466...53,901,812 		JBrowse link
G Amacr alpha-methylacyl-CoA racemase decreases expression ISO Isotretinoin results in decreased expression of AMACR mRNA CTD PMID:20436886 NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255 		JBrowse link
G Ank2 ankyrin 2 increases expression ISO Isotretinoin results in increased expression of ANK2 mRNA CTD PMID:20436886 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923 		JBrowse link
G Ankhd1 ankyrin repeat and KH domain containing 1 decreases expression ISO Isotretinoin results in decreased expression of ANKHD1 mRNA CTD PMID:20436886 NCBI chr18:28,161,882...28,260,917
Ensembl chr18:28,162,311...28,268,024 		JBrowse link
G Ano10 anoctamin 10 decreases expression ISO Isotretinoin results in decreased expression of ANO10 mRNA CTD PMID:20436886 NCBI chr 8:121,841,664...121,960,739
Ensembl chr 8:121,841,665...121,962,670 		JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 increases expression ISO Isotretinoin results in increased expression of AP2B1 mRNA CTD PMID:20436886 NCBI chr10:68,099,397...68,205,023
Ensembl chr10:68,099,547...68,205,013 		JBrowse link
G Ap3s2 adaptor related protein complex 3 subunit sigma 2 decreases expression ISO Isotretinoin results in decreased expression of AP3S2 mRNA CTD PMID:20436886 NCBI chr 1:133,818,825...133,859,269
Ensembl chr 1:133,818,825...133,859,322 		JBrowse link
G Apoc1 apolipoprotein C1 decreases expression ISO Isotretinoin results in decreased expression of APOC1 mRNA CTD PMID:20436886 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375 		JBrowse link
G Apoe apolipoprotein E affects response to substance ISO APOE gene polymorphism affects the susceptibility to Isotretinoin CTD PMID:12622636 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Apool apolipoprotein O-like decreases expression ISO Isotretinoin results in decreased expression of APOOL mRNA CTD PMID:20436886 NCBI chr  X:77,377,685...77,443,670
Ensembl chr  X:77,377,781...77,443,900 		JBrowse link
G Areg amphiregulin multiple interactions ISO Isotretinoin inhibits the reaction [Calcitriol results in increased expression of AREG mRNA] CTD PMID:11237771 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Arg2 arginase 2 decreases expression ISO Isotretinoin results in decreased expression of ARG2 mRNA CTD PMID:20436886 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases expression ISO Isotretinoin results in increased expression of ARHGDIB mRNA CTD PMID:20436886 NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658 		JBrowse link
G Arhgef6 Rac/Cdc42 guanine nucleotide exchange factor 6 increases expression ISO Isotretinoin results in increased expression of ARHGEF6 mRNA CTD PMID:20436886 NCBI chr  X:135,145,447...135,264,636
Ensembl chr  X:135,146,786...135,275,304 		JBrowse link
G Artn artemin multiple interactions ISO [vorinostat co-treated with Isotretinoin] results in increased expression of ARTN mRNA CTD PMID:18769122 NCBI chr 5:131,458,596...131,470,193
Ensembl chr 5:131,464,756...131,468,025 		JBrowse link
G Asap3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 increases expression ISO Isotretinoin results in increased expression of ASAP3 mRNA CTD PMID:20436886 NCBI chr 5:148,433,382...148,476,027
Ensembl chr 5:148,433,494...148,474,073 		JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO Isotretinoin affects the localization of and results in decreased activity of ATF2 protein CTD PMID:18652567 PMID:19066126 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Atf5 activating transcription factor 5 multiple interactions ISO [vorinostat co-treated with Isotretinoin] results in decreased expression of ATF5 mRNA CTD PMID:18769122 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707 		JBrowse link
G Atg4a autophagy related 4A, cysteine peptidase decreases expression ISO Isotretinoin results in decreased expression of ATG4A mRNA CTD PMID:20436886 NCBI chr  X:104,665,345...104,765,271
Ensembl chr  X:104,665,345...104,765,268 		JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 increases expression ISO Isotretinoin results in increased expression of ATP2B4 mRNA CTD PMID:20436886 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246 		JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma decreases expression ISO Isotretinoin results in decreased expression of ATP5F1C mRNA CTD PMID:20436886 NCBI chr17:68,423,927...68,446,169
Ensembl chr17:68,423,909...68,608,367 		JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 decreases expression ISO Isotretinoin results in decreased expression of ATP5MC3 mRNA CTD PMID:20436886 NCBI chr 3:58,810,535...58,813,185
Ensembl chr 3:58,810,535...58,814,279 		JBrowse link
G Atp5mf ATP synthase membrane subunit f decreases expression ISO Isotretinoin results in decreased expression of ATP5MF mRNA CTD PMID:20436886 NCBI chr12:9,421,665...9,428,236
Ensembl chr12:9,421,579...9,428,236 		JBrowse link
G Atp5mj-ps1 ATP synthase membrane subunit j, pseudogene 1 decreases expression ISO Isotretinoin results in decreased expression of ATP5MJ mRNA CTD PMID:20436886 NCBI chr 1:168,472,019...168,472,630
Ensembl chr 1:168,472,329...168,472,610 		JBrowse link
G Atp6v0b ATPase H+ transporting V0 subunit B decreases expression ISO Isotretinoin results in decreased expression of ATP6V0B mRNA CTD PMID:20436886 NCBI chr 5:131,423,384...131,424,900
Ensembl chr 5:131,423,387...131,426,401 		JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C decreases expression ISO Isotretinoin results in decreased expression of ATP6V0C mRNA CTD PMID:20436886 NCBI chr10:13,196,204...13,202,580
Ensembl chr10:13,196,204...13,201,500 		JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D decreases expression ISO Isotretinoin results in decreased expression of ATP6V1D mRNA CTD PMID:20436886 NCBI chr 6:97,656,725...97,672,211
Ensembl chr 6:97,656,576...97,672,303 		JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression ISO Isotretinoin results in increased expression of BASP1 mRNA CTD PMID:20436886 NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Isotretinoin results in increased expression of BAX; Isotretinoin results in increased expression of BAX protein CTD PMID:16109544 PMID:16135400 PMID:16909596 PMID:27606422 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbln bublin coiled coil protein decreases expression ISO Isotretinoin results in decreased expression of BBLN mRNA CTD PMID:20436886 NCBI chr 3:15,674,577...15,677,393
Ensembl chr 3:15,674,580...15,677,374 		JBrowse link
G Bcap29 B-cell receptor-associated protein 29 decreases expression ISO Isotretinoin results in decreased expression of BCAP29 mRNA CTD PMID:20436886 NCBI chr 6:48,182,702...48,222,698
Ensembl chr 6:48,182,706...48,222,720 		JBrowse link
G Bcap31 B-cell receptor-associated protein 31 decreases expression ISO Isotretinoin results in decreased expression of BCAP31 mRNA CTD PMID:20436886 NCBI chr  X:151,397,567...151,429,666
Ensembl chr  X:151,397,576...151,428,506 		JBrowse link
G Bcat2 branched chain amino acid transaminase 2 decreases expression ISO Isotretinoin results in decreased expression of BCAT2 mRNA CTD PMID:20436886 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007 		JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta decreases expression ISO Isotretinoin results in decreased expression of BCKDHB mRNA CTD PMID:20436886 NCBI chr 8:84,845,264...85,027,812
Ensembl chr 8:84,845,264...85,027,812 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
increases expression		 ISO Isotretinoin results in decreased expression of BCL2; Isotretinoin results in decreased expression of BCL2 protein
Isotretinoin results in increased expression of BCL2 mRNA; Isotretinoin results in increased expression of BCL2 protein
Isotretinoin results in decreased expression of BCL2; Isotretinoin results in decreased expression of BCL2 mRNA; Isotretinoin results in decreased expression of BCL2 protein		 CTD PMID:16109544 PMID:16909596 PMID:18380168 PMID:18652567 PMID:21159604 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
decreases expression		 ISO Isotretinoin results in increased expression of BCL2L1 mRNA; Isotretinoin results in increased expression of BCL2L1 protein
Isotretinoin results in decreased expression of BCL2L1 protein		 CTD PMID:16135400 PMID:21159604 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 decreases expression ISO Isotretinoin results in decreased expression of BDH1 mRNA CTD PMID:20436886 NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671 		JBrowse link
G Bean1 brain expressed, associated with NEDD4, 1 decreases expression ISO Isotretinoin results in decreased expression of BEAN1 mRNA CTD PMID:20436886 NCBI chr19:739,551...786,122
Ensembl chr19:739,551...787,537 		JBrowse link
G Bend5 BEN domain containing 5 increases expression ISO Isotretinoin results in increased expression of BEND5 mRNA CTD PMID:20436886 NCBI chr 5:126,290,648...126,336,662
Ensembl chr 5:125,254,956...126,534,367 		JBrowse link
G Bgn biglycan increases expression ISO Isotretinoin results in increased expression of BGN mRNA CTD PMID:20436886 NCBI chr  X:151,197,296...151,209,458
Ensembl chr  X:151,197,273...151,209,461 		JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO Isotretinoin results in increased expression of BHLHE40 mRNA CTD PMID:18769122 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO Isotretinoin results in decreased expression of BIRC5 protein CTD PMID:16135400 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Blvrb biliverdin reductase B decreases expression ISO Isotretinoin results in decreased expression of BLVRB mRNA CTD PMID:20436886 NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375 		JBrowse link
G Bmerb1 bMERB domain containing 1 increases expression ISO Isotretinoin results in increased expression of BMERB1 mRNA CTD PMID:20436886 NCBI chr10:1,779,834...1,946,586
Ensembl chr10:1,779,835...1,946,575 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase decreases expression ISO Isotretinoin results in decreased expression of BRAF mRNA CTD PMID:20436886 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G Bsg basigin (Ok blood group) decreases expression ISO Isotretinoin results in decreased expression of BSG mRNA CTD PMID:20436886 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387 		JBrowse link
G Btbd3 BTB domain containing 3 increases expression ISO Isotretinoin results in increased expression of BTBD3 mRNA CTD PMID:20436886 NCBI chr 3:125,591,427...125,621,660
Ensembl chr 3:125,591,490...125,619,038 		JBrowse link
G Btd biotinidase decreases expression ISO Isotretinoin results in decreased expression of BTD mRNA CTD PMID:20436886 NCBI chr16:6,863,068...6,894,345
Ensembl chr16:6,862,407...6,940,945 		JBrowse link
G C1r complement C1r increases expression ISO Isotretinoin results in increased expression of C1R mRNA CTD PMID:20436886 NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484 		JBrowse link
G C1s complement C1s increases expression ISO Isotretinoin results in increased expression of C1S mRNA CTD PMID:20436886 NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303 		JBrowse link
G C3 complement C3 increases expression ISO Isotretinoin results in increased expression of C3 mRNA CTD PMID:20436886 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Cald1 caldesmon 1 increases expression ISO Isotretinoin results in increased expression of CALD1 mRNA CTD PMID:20436886 NCBI chr 4:63,265,781...63,446,936
Ensembl chr 4:63,265,942...63,446,932 		JBrowse link
G Calml3 calmodulin-like 3 decreases expression ISO Isotretinoin results in decreased expression of CALML3 mRNA CTD PMID:20436886 NCBI chr17:66,419,844...66,423,083
Ensembl chr17:66,419,882...66,423,175 		JBrowse link
G Casp3 caspase 3 increases cleavage
increases expression		 ISO Isotretinoin results in increased cleavage of CASP3 protein
Isotretinoin results in increased expression of CASP3; Isotretinoin results in increased expression of CASP3 protein
Isotretinoin results in increased expression of CASP3; Isotretinoin results in increased expression of CASP3 mRNA		 CTD PMID:16109544 PMID:16135400 PMID:16157052 PMID:16575387 PMID:16909596 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 increases cleavage
increases expression		 ISO Isotretinoin results in increased cleavage of CASP8 protein
Isotretinoin results in increased expression of CASP8 protein		 CTD PMID:16135400 PMID:27606422 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases expression ISO Isotretinoin results in increased expression of CASP9 protein CTD PMID:27606422 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions
decreases activity		 ISO
EXP		 Isotretinoin inhibits the reaction [Benzoyl Peroxide results in decreased activity of CAT protein]
Isotretinoin results in decreased activity of CAT protein		 CTD PMID:15225900 PMID:35752295 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cavin1 caveolae associated protein 1 increases expression ISO Isotretinoin results in increased expression of CAVIN1 mRNA CTD PMID:20436886 NCBI chr10:85,884,100...85,896,136
Ensembl chr10:85,889,036...85,896,120 		JBrowse link
G Cbx3 chromobox 3 decreases expression ISO Isotretinoin results in decreased expression of CBX3 mRNA CTD PMID:15982314 NCBI chr 4:80,545,450...80,559,284
Ensembl chr 4:80,546,010...80,559,283 		JBrowse link
G Ccdc86 coiled-coil domain containing 86 decreases expression ISO Isotretinoin results in decreased expression of CCDC86 mRNA CTD PMID:20436886 NCBI chr 1:207,590,946...207,596,527
Ensembl chr 1:207,590,168...207,596,544 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression EXP Isotretinoin results in decreased expression of CCL2 mRNA CTD PMID:15972972 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression EXP Isotretinoin results in decreased expression of CCL3 mRNA CTD PMID:15972972 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions
decreases expression		 ISO
EXP		 Isotretinoin inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; Isotretinoin inhibits the reaction [TNF protein results in increased secretion of CCL5 protein]
Isotretinoin results in decreased expression of CCL5 mRNA		 CTD PMID:15972972 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Isotretinoin results in decreased expression of CCND1 protein CTD PMID:16575387 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cd2 Cd2 molecule increases expression ISO Isotretinoin results in increased expression of CD2 mRNA CTD PMID:20436886 NCBI chr 2:188,710,895...188,724,044
Ensembl chr 2:188,710,900...188,724,026 		JBrowse link
G Cd247 Cd247 molecule increases expression ISO Isotretinoin results in increased expression of CD3Z mRNA CTD PMID:20436886 NCBI chr13:78,043,302...78,118,437
Ensembl chr13:78,043,307...78,122,263 		JBrowse link
G Cd34 CD34 molecule increases expression ISO Isotretinoin results in increased expression of CD34 mRNA CTD PMID:20436886 NCBI chr13:106,480,074...106,499,462
Ensembl chr13:106,480,043...106,499,832 		JBrowse link
G Cd37 CD37 molecule increases expression ISO Isotretinoin results in increased expression of CD37 mRNA CTD PMID:20436886 NCBI chr 1:95,719,171...95,724,662
Ensembl chr 1:95,719,190...95,724,648 		JBrowse link
G Cd38 CD38 molecule increases expression ISO Isotretinoin results in increased expression of CD38 protein CTD PMID:16275619 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986 		JBrowse link
G Cd3d CD3 delta subunit of T-cell receptor complex increases expression ISO Isotretinoin results in increased expression of CD3D mRNA CTD PMID:20436886 NCBI chr 8:45,287,803...45,293,342
Ensembl chr 8:45,288,749...45,301,809 		JBrowse link
G Cd52 CD52 molecule increases expression ISO Isotretinoin results in increased expression of CD52 mRNA CTD PMID:20436886 NCBI chr 5:146,319,789...146,321,348
Ensembl chr 5:146,319,969...146,321,348 		JBrowse link
G Cd69 Cd69 molecule multiple interactions ISO [Dacarbazine co-treated with Isotretinoin] affects the reaction [IFNA2 protein results in increased expression of CD69 protein] CTD PMID:17973783 NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542 		JBrowse link
G Cd81 Cd81 molecule increases expression ISO Isotretinoin results in increased expression of CD81 mRNA CTD PMID:20436886 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660 		JBrowse link
G Cda cytidine deaminase decreases expression ISO Isotretinoin results in decreased expression of CDA mRNA CTD PMID:20436886 NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231 		JBrowse link
G Cdc14b cell division cycle 14B increases expression ISO Isotretinoin results in increased expression of CDC14B mRNA CTD PMID:20436886 NCBI chr17:844,731...934,787
Ensembl chr17:844,685...933,235 		JBrowse link
G Cdh5 cadherin 5 increases expression ISO Isotretinoin results in increased expression of CDH5 mRNA CTD PMID:18769122 NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 decreases expression ISO Isotretinoin results in decreased expression of CDK5 mRNA CTD PMID:20436886 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 decreases expression ISO Isotretinoin results in decreased expression of CDK5RAP1 mRNA CTD PMID:20436886 NCBI chr 3:142,838,081...142,872,669
Ensembl chr 3:142,708,028...142,872,677 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression
increases expression
multiple interactions		 ISO Isotretinoin results in decreased expression of CDKN1A mRNA
Isotretinoin results in increased expression of CDKN1A protein
[LAQ824 co-treated with Isotretinoin] results in increased expression of CDKN1A mRNA; [LAQ824 co-treated with Isotretinoin] results in increased expression of CDKN1A protein		 CTD PMID:16575387 PMID:17237267 PMID:20436886 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression ISO Isotretinoin results in decreased expression of CDKN1C mRNA CTD PMID:15982314 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 decreases expression ISO Isotretinoin results in decreased expression of CEACAM1 mRNA CTD PMID:20436886 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Cel carboxyl ester lipase increases expression ISO Isotretinoin results in increased expression of CEL mRNA CTD PMID:18769122 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035 		JBrowse link
G Celf2 CUGBP, Elav-like family member 2 increases expression ISO Isotretinoin results in increased expression of CELF2 mRNA CTD PMID:20436886 NCBI chr17:70,904,462...71,729,072
Ensembl chr17:71,210,853...71,728,333 		JBrowse link
G Cers4 ceramide synthase 4 decreases expression ISO Isotretinoin results in decreased expression of CERS4 mRNA CTD PMID:20436886 NCBI chr12:2,851,784...2,890,244
Ensembl chr12:2,851,784...2,886,828 		JBrowse link
G Cfap45 cilia and flagella associated protein 45 decreases expression ISO Isotretinoin results in decreased expression of CFAP45 mRNA CTD PMID:20436886 NCBI chr13:84,989,474...85,012,880
Ensembl chr13:84,981,728...85,012,878 		JBrowse link
G Chi3l1 chitinase 3 like 1 decreases expression ISO Isotretinoin results in decreased expression of CHI3L1 mRNA CTD PMID:20436886 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787 		JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 decreases expression ISO Isotretinoin results in decreased expression of CHP1 mRNA CTD PMID:20436886 NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251 		JBrowse link
G Chst5 carbohydrate sulfotransferase 5 increases expression ISO Isotretinoin results in increased expression of CHST6 mRNA CTD PMID:20436886 NCBI chr19:39,860,729...39,881,019
Ensembl chr19:39,860,501...39,881,064 		JBrowse link
G Cidea cell death-inducing DFFA-like effector a decreases expression ISO Isotretinoin results in decreased expression of CIDEA mRNA CTD PMID:20436886 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481 		JBrowse link
G Ckb creatine kinase B decreases expression ISO Isotretinoin results in decreased expression of CKB mRNA CTD PMID:15982314 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315 		JBrowse link
G Ckm creatine kinase, M-type increases expression ISO Isotretinoin results in increased expression of CKM protein CTD PMID:9747221 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720 		JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1 decreases expression ISO Isotretinoin results in decreased expression of CKMT1 mRNA CTD PMID:20436886 NCBI chr 3:108,329,859...108,335,760
Ensembl chr 3:108,330,705...108,335,758 		JBrowse link
G Clcn3 chloride voltage-gated channel 3 decreases expression ISO Isotretinoin results in decreased expression of CLCN3 mRNA CTD PMID:20436886 NCBI chr16:29,127,419...29,200,133
Ensembl chr16:29,127,419...29,200,119 		JBrowse link
G Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit X decreases expression ISO Isotretinoin results in decreased expression of CLPX mRNA CTD PMID:20436886 NCBI chr 8:65,805,460...65,845,643
Ensembl chr 8:65,805,511...65,845,082 		JBrowse link
G Clstn3 calsyntenin 3 decreases expression ISO Isotretinoin results in decreased expression of CLSTN3 mRNA CTD PMID:20436886 NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769 		JBrowse link
G Cndp2 carnosine dipeptidase 2 decreases expression ISO Isotretinoin results in decreased expression of CNDP2 mRNA CTD PMID:20436886 NCBI chr18:78,039,924...78,057,030
Ensembl chr18:78,039,932...78,056,922 		JBrowse link
G Coch cochlin increases expression ISO Isotretinoin results in increased expression of COCH mRNA CTD PMID:20436886 NCBI chr 6:69,031,139...69,045,124
Ensembl chr 6:69,031,167...69,045,109 		JBrowse link
G Col14a1 collagen type XIV alpha 1 chain increases expression ISO Isotretinoin results in increased expression of COL14A1 mRNA CTD PMID:20436886 NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214 		JBrowse link
G Col17a1 collagen type XVII alpha 1 chain decreases expression ISO Isotretinoin results in decreased expression of COL17A1 mRNA CTD PMID:15982314 NCBI chr 1:246,530,589...246,577,632
Ensembl chr 1:246,531,367...246,577,632 		JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression EXP Isotretinoin results in decreased expression of COL1A1 mRNA; Isotretinoin results in decreased expression of COL1A1 protein CTD PMID:15972972 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression EXP Isotretinoin results in decreased expression of COL3A1 mRNA; Isotretinoin results in decreased expression of COL3A1 protein CTD PMID:15972972 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Col4a2 collagen type IV alpha 2 chain increases expression ISO Isotretinoin results in increased expression of COL4A2 mRNA CTD PMID:20436886 NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839 		JBrowse link
G Col5a1 collagen type V alpha 1 chain increases expression ISO Isotretinoin results in increased expression of COL5A1 mRNA CTD PMID:20436886 NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588 		JBrowse link
G Col5a2 collagen type V alpha 2 chain increases expression ISO Isotretinoin results in increased expression of COL5A2 mRNA CTD PMID:20436886 NCBI chr 9:47,448,736...47,598,396
Ensembl chr 9:47,448,736...47,598,154 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain decreases expression
increases expression		 ISO Isotretinoin results in decreased expression of COL6A1 mRNA
Isotretinoin results in increased expression of COL6A1 mRNA		 CTD PMID:15982314 PMID:20436886 NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597 		JBrowse link
G Col6a2 collagen type VI alpha 2 chain increases expression ISO Isotretinoin results in increased expression of COL6A2 mRNA CTD PMID:20436886 NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564 		JBrowse link
G Col6a3 collagen type VI alpha 3 chain increases expression ISO Isotretinoin results in increased expression of COL6A3 mRNA CTD PMID:20436886 NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471 		JBrowse link
G Col8a2 collagen type VIII alpha 2 chain decreases expression ISO Isotretinoin results in decreased expression of COL8A2 mRNA CTD PMID:15982314 NCBI chr 5:138,586,201...138,613,627
Ensembl chr 5:138,585,999...138,612,850 		JBrowse link
G Cox5a cytochrome c oxidase subunit 5A decreases expression ISO Isotretinoin results in decreased expression of COX5A mRNA CTD PMID:20436886 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781 		JBrowse link
G Cox5b cytochrome c oxidase subunit 5B decreases expression ISO Isotretinoin results in decreased expression of COX5B mRNA CTD PMID:20436886 NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052 		JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 decreases expression ISO Isotretinoin results in decreased expression of COX6A1 mRNA CTD PMID:20436886 NCBI chr12:41,261,983...41,265,037
Ensembl chr12:41,261,967...41,265,041 		JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 decreases expression ISO Isotretinoin results in decreased expression of COX7A2 mRNA CTD PMID:20436886 NCBI chr 8:80,716,824...80,720,922
Ensembl chr14:51,301,168...51,301,633 		JBrowse link
G Cox7b cytochrome c oxidase subunit 7B decreases expression ISO Isotretinoin results in decreased expression of COX7B mRNA CTD PMID:20436886 NCBI chr  X:71,083,486...71,089,733
Ensembl chr  X:71,083,456...71,089,732 		JBrowse link
G Cpd carboxypeptidase D decreases expression ISO Isotretinoin results in decreased expression of CPD mRNA CTD PMID:20436886 NCBI chr10:61,623,528...61,687,491
Ensembl chr10:61,623,526...61,687,491 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 decreases expression ISO Isotretinoin results in decreased expression of CPT2 mRNA CTD PMID:20436886 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression
multiple interactions		 ISO Isotretinoin results in increased expression of CRABP2 mRNA
R116010 promotes the reaction [Isotretinoin results in increased expression of CRABP2 mRNA]		 CTD PMID:17486130 NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379 		JBrowse link
G Crat carnitine O-acetyltransferase decreases expression ISO Isotretinoin results in decreased expression of CRAT mRNA CTD PMID:20436886 NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation ISO Isotretinoin results in increased phosphorylation of CREB1 protein CTD PMID:16280361 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Cript CXXC repeat containing interactor of PDZ3 domain decreases expression ISO Isotretinoin results in decreased expression of CRIPT mRNA CTD PMID:20436886 NCBI chr 6:7,581,428...7,589,384
Ensembl chr 6:7,580,703...7,589,399 		JBrowse link
G Crtc3 CREB regulated transcription coactivator 3 increases expression ISO Isotretinoin results in increased expression of CRTC3 mRNA CTD PMID:20436886 NCBI chr 1:134,552,830...134,655,929
Ensembl chr 1:134,554,696...134,655,500 		JBrowse link
G Cryz crystallin zeta multiple interactions ISO Isotretinoin inhibits the reaction [Benzoyl Peroxide results in decreased activity of CRYZ protein] CTD PMID:15225900 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758 		JBrowse link
G Csf1r colony stimulating factor 1 receptor increases expression ISO Isotretinoin results in increased expression of CSF1R mRNA CTD PMID:20436886 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Csf2 colony stimulating factor 2 decreases secretion EXP Isotretinoin results in decreased secretion of CSF2 protein CTD PMID:15972972 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Cst3 cystatin C increases expression ISO Isotretinoin results in increased expression of CST3 mRNA CTD PMID:20436886 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822 		JBrowse link
G Cstb cystatin B decreases expression ISO Isotretinoin results in decreased expression of CSTB mRNA CTD PMID:20436886 NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526 		JBrowse link
G Cth cystathionine gamma-lyase decreases expression ISO Isotretinoin results in decreased expression of CTH mRNA CTD PMID:20436886 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Cttn cortactin decreases expression ISO Isotretinoin results in decreased expression of CTTN mRNA CTD PMID:20436886 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164 		JBrowse link
G Cux2 cut-like homeobox 2 decreases expression ISO Isotretinoin results in decreased expression of CUX2 mRNA CTD PMID:20436886 NCBI chr12:34,507,723...34,707,581
Ensembl chr12:34,520,959...34,705,806 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 decreases expression ISO Isotretinoin results in decreased expression of CXCL1 mRNA CTD PMID:15982314 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression ISO
EXP		 Isotretinoin results in decreased expression of CXCL10 mRNA CTD PMID:15972972 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO Isotretinoin results in increased expression of CXCL12 mRNA CTD PMID:20436886 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression ISO Isotretinoin results in decreased expression of CXCL1 mRNA CTD PMID:15982314 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cyb5a cytochrome b5 type A decreases expression ISO Isotretinoin results in decreased expression of CYB5A mRNA CTD PMID:20436886 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression ISO Isotretinoin results in increased expression of CYP26A1 mRNA CTD PMID:16194896 PMID:17486130 PMID:18769122 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 multiple interactions
increases expression		 ISO R116010 promotes the reaction [Isotretinoin results in increased expression of CYP26B1 mRNA] CTD PMID:17486130 PMID:18769122 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression ISO Isotretinoin results in decreased expression of CYP27A1 mRNA CTD PMID:15982314 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases activity		 ISO [Isotretinoin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; Isotretinoin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]
Isotretinoin results in increased activity of CYP3A4 protein		 CTD PMID:16632523 PMID:25455453 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 decreases expression ISO Isotretinoin results in decreased expression of CYP4F3 mRNA CTD PMID:20436886 NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940 		JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 decreases expression ISO Isotretinoin results in decreased expression of CYP4F8 mRNA CTD PMID:20436886 NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782 		JBrowse link
G Cyp51 cytochrome P450, family 51 decreases expression ISO Isotretinoin results in decreased expression of CYP51A1 mRNA CTD PMID:20436886 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410 		JBrowse link
G Dbi diazepam binding inhibitor decreases expression ISO Isotretinoin results in decreased expression of DBI mRNA CTD PMID:20436886 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693 		JBrowse link
G Dbn1 drebrin 1 increases expression ISO Isotretinoin results in increased expression of DBN1 mRNA CTD PMID:20436886 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984 		JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 decreases expression ISO Isotretinoin results in decreased expression of DBT mRNA CTD PMID:20436886 NCBI chr 2:204,481,744...204,510,612
Ensembl chr 2:204,481,737...204,510,609 		JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase decreases expression ISO Isotretinoin results in decreased expression of DCXR mRNA CTD PMID:20436886 NCBI chr10:106,006,404...106,008,294 JBrowse link
G Ddc dopa decarboxylase decreases expression ISO Isotretinoin results in decreased expression of DDC mRNA CTD PMID:20436886 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Ddo D-aspartate oxidase decreases expression ISO Isotretinoin results in decreased expression of DDO mRNA CTD PMID:20436886 NCBI chr20:44,090,823...44,109,962
Ensembl chr20:44,090,914...44,133,095 		JBrowse link
G Ddt D-dopachrome tautomerase decreases expression ISO Isotretinoin results in decreased expression of DDT mRNA CTD PMID:20436886 NCBI chr20:12,884,216...12,886,687
Ensembl chr20:12,884,243...12,888,482 		JBrowse link
G Dennd5a DENN domain containing 5A increases expression ISO Isotretinoin results in increased expression of DENND5A mRNA CTD PMID:20436886 NCBI chr 1:163,928,183...163,994,207
Ensembl chr 1:163,928,183...163,994,316 		JBrowse link
G Desi1 desumoylating isopeptidase 1 decreases expression ISO Isotretinoin results in decreased expression of DESI1 mRNA CTD PMID:20436886 NCBI chr 7:113,519,974...113,542,834
Ensembl chr 7:113,519,980...113,542,845 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO Isotretinoin results in decreased expression of DHCR24 mRNA CTD PMID:20436886 NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression ISO Isotretinoin results in decreased expression of DHCR7 mRNA CTD PMID:20436886 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Dhfr dihydrofolate reductase decreases expression ISO Isotretinoin results in decreased expression of DHFR mRNA CTD PMID:20436886 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Dhrs11 dehydrogenase/reductase 11 decreases expression ISO Isotretinoin results in decreased expression of DHRS11 mRNA CTD PMID:20436886 NCBI chr10:69,698,214...69,708,294
Ensembl chr10:69,698,214...69,708,295 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases expression ISO Isotretinoin results in increased expression of DHRS3 mRNA CTD PMID:18769122 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417 		JBrowse link
G Dhrs7b dehydrogenase/reductase 7B decreases expression ISO Isotretinoin results in decreased expression of DHRS7B mRNA CTD PMID:20436886 NCBI chr10:45,504,344...45,537,094
Ensembl chr10:45,504,426...45,537,076 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 multiple interactions
decreases expression		 ISO [vorinostat co-treated with Isotretinoin] results in increased expression of DHRS9 mRNA
Isotretinoin results in decreased expression of DHRS9 mRNA		 CTD PMID:18769122 PMID:20436886 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241 		JBrowse link
G Diras3 DIRAS family GTPase 3 decreases expression ISO Isotretinoin results in decreased expression of DIRAS3 mRNA CTD PMID:20436886 NCBI chr 6:130,524,972...130,527,690
Ensembl chr 6:130,524,742...130,530,825 		JBrowse link
G Dixdc1 DIX domain containing 1 increases expression ISO Isotretinoin results in increased expression of DIXDC1 mRNA CTD PMID:20436886 NCBI chr 8:51,007,835...51,081,191
Ensembl chr 8:51,007,838...51,081,090 		JBrowse link
G Dld dihydrolipoamide dehydrogenase decreases expression ISO Isotretinoin results in decreased expression of DLD mRNA CTD PMID:20436886 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795 		JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 increases expression ISO Isotretinoin results in increased expression of DLG5 mRNA CTD PMID:20436886 NCBI chr15:75,786...209,735
Ensembl chr15:75,786...187,837 		JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase increases expression ISO Isotretinoin results in increased expression of DLST protein CTD PMID:15982314 NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296 		JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 decreases expression ISO Isotretinoin results in decreased expression of DNAJA3 mRNA CTD PMID:20436886 NCBI chr10:10,855,510...10,880,175
Ensembl chr10:10,854,732...10,880,161 		JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 decreases expression ISO Isotretinoin results in decreased expression of DNAJC15 mRNA CTD PMID:20436886 NCBI chr15:53,182,060...53,249,675
Ensembl chr15:53,184,855...53,249,675 		JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 decreases expression ISO Isotretinoin results in decreased expression of DNAJC3 mRNA CTD PMID:20436886 NCBI chr15:96,025,729...96,065,114
Ensembl chr15:96,025,624...96,065,181 		JBrowse link
G Dnase1 deoxyribonuclease 1 increases expression ISO Isotretinoin results in increased expression of DNASE1 protein CTD PMID:15982314 NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869 		JBrowse link
G Dnase1l2 deoxyribonuclease 1 like 2 decreases expression ISO Isotretinoin results in decreased expression of DNASE1L2 mRNA CTD PMID:20436886 NCBI chr10:13,471,850...13,473,447
Ensembl chr10:13,471,479...13,473,763 		JBrowse link
G Dnm1 dynamin 1 increases expression ISO Isotretinoin results in increased expression of DNM1 mRNA CTD PMID:20436886 NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538 		JBrowse link
G Dop1b DOP1 leucine zipper like protein B decreases expression ISO Isotretinoin results in decreased expression of DOP1B mRNA CTD PMID:20436886 NCBI chr11:33,024,376...33,125,931
Ensembl chr11:33,024,411...33,125,931 		JBrowse link
G Dpp3 dipeptidylpeptidase 3 decreases expression ISO Isotretinoin results in decreased expression of DPP3 mRNA CTD PMID:20436886 NCBI chr 1:202,204,683...202,228,501
Ensembl chr 1:202,204,693...202,228,541 		JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 increases expression ISO Isotretinoin results in increased expression of DPYSL2 mRNA CTD PMID:20436886 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829 		JBrowse link
G Drp2 dystrophin related protein 2 decreases expression ISO Isotretinoin results in decreased expression of DRP2 mRNA CTD PMID:20436886 NCBI chr  X:97,607,577...97,658,115
Ensembl chr  X:97,607,719...97,655,684 		JBrowse link
G Dsc1 desmocollin 1 decreases expression ISO Isotretinoin results in decreased expression of DSC1 mRNA CTD PMID:15982314 NCBI chr18:11,499,936...11,556,801
Ensembl chr18:11,502,003...11,528,494 		JBrowse link
G Dsc2 desmocollin 2 decreases expression ISO Isotretinoin results in decreased expression of DSC2 mRNA CTD PMID:20436886 NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392 		JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO Isotretinoin results in increased expression of DUSP10 mRNA CTD PMID:15982314 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Dusp11 dual specificity phosphatase 11 decreases expression ISO Isotretinoin results in decreased expression of DUSP11 mRNA CTD PMID:15982314 NCBI chr 4:118,367,673...118,385,183
Ensembl chr 4:118,368,053...118,385,181 		JBrowse link
G Dusp4 dual specificity phosphatase 4 decreases expression ISO Isotretinoin results in decreased expression of DUSP4 mRNA CTD PMID:20436886 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138 		JBrowse link
G E2f8 E2F transcription factor 8 decreases expression ISO Isotretinoin results in decreased expression of E2F8 mRNA CTD PMID:20436886 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098 		JBrowse link
G Ebp EBP, cholestenol delta-isomerase decreases expression ISO Isotretinoin results in decreased expression of EBP mRNA CTD PMID:20436886 NCBI chr  X:14,299,427...14,305,826
Ensembl chr  X:14,299,448...14,305,826 		JBrowse link
G Ech1 enoyl-CoA hydratase 1 decreases expression ISO Isotretinoin results in decreased expression of ECH1 mRNA CTD PMID:20436886 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795 		JBrowse link
G Echdc1 ethylmalonyl-CoA decarboxylase 1 decreases expression ISO Isotretinoin results in decreased expression of ECHDC1 mRNA CTD PMID:20436886 NCBI chr 1:28,476,354...28,507,173
Ensembl chr 1:28,476,200...28,507,319 		JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 decreases expression ISO Isotretinoin results in decreased expression of ECI1 mRNA CTD PMID:20436886 NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061 		JBrowse link
G Efemp2 EGF containing fibulin extracellular matrix protein 2 increases expression ISO Isotretinoin results in increased expression of EFEMP2 mRNA CTD PMID:20436886 NCBI chr 1:202,781,692...202,789,784
Ensembl chr 1:202,781,665...202,789,414 		JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO Isotretinoin results in decreased expression of EGFR mRNA CTD PMID:15982314 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egr3 early growth response 3 decreases expression ISO Isotretinoin results in decreased expression of EGR3 mRNA CTD PMID:20436886 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627 		JBrowse link
G Ei24 EI24, autophagy associated transmembrane protein decreases expression ISO Isotretinoin results in decreased expression of EI24 mRNA CTD PMID:20436886 NCBI chr 8:36,494,289...36,510,653
Ensembl chr 8:36,494,289...36,510,571 		JBrowse link
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma decreases expression ISO Isotretinoin results in decreased expression of EIF2B3 mRNA CTD PMID:20436886 NCBI chr 5:130,492,167...130,558,692
Ensembl chr 5:130,492,220...130,563,332 		JBrowse link
G Eif4e eukaryotic translation initiation factor 4E decreases expression ISO Isotretinoin results in decreased expression of EIF4E mRNA CTD PMID:20436886 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683 		JBrowse link
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 decreases expression ISO Isotretinoin results in decreased expression of EIF4EBP2 mRNA CTD PMID:15982314 NCBI chr20:29,379,444...29,400,131
Ensembl chr20:29,382,668...29,399,946 		JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 decreases expression ISO Isotretinoin results in decreased expression of ELL2 mRNA CTD PMID:20436886 NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 decreases expression ISO Isotretinoin results in decreased expression of ELOVL1 mRNA CTD PMID:20436886 NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958 		JBrowse link
G Elovl4 ELOVL fatty acid elongase 4 decreases expression ISO Isotretinoin results in decreased expression of ELOVL4 mRNA CTD PMID:20436886 NCBI chr 8:84,702,916...84,729,466
Ensembl chr 8:84,702,362...84,729,697 		JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 decreases expression ISO Isotretinoin results in decreased expression of ELOVL5 mRNA CTD PMID:20436886 NCBI chr 8:78,790,799...78,857,307
Ensembl chr 8:78,790,846...78,857,284 		JBrowse link
G Emp1 epithelial membrane protein 1 increases expression ISO Isotretinoin results in increased expression of EMP1 mRNA CTD PMID:15982314 NCBI chr 4:168,212,901...168,233,039
Ensembl chr 4:168,212,861...168,232,904 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit decreases expression ISO Isotretinoin results in decreased expression of ERCC1 mRNA CTD PMID:20436886 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Erg28 ergosterol biosynthesis 28 homolog decreases expression ISO Isotretinoin results in decreased expression of ERG28 mRNA CTD PMID:20436886 NCBI chr 6:105,474,112...105,483,078
Ensembl chr 6:105,474,113...105,483,078 		JBrowse link
G Esr2 estrogen receptor 2 decreases expression EXP Isotretinoin results in decreased expression of ESR2 mRNA CTD PMID:19041696 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Etfdh electron transfer flavoprotein dehydrogenase decreases expression ISO Isotretinoin results in decreased expression of ETFDH mRNA CTD PMID:20436886 NCBI chr 2:164,740,547...164,762,754
Ensembl chr 2:164,729,749...164,762,745 		JBrowse link
G Etnk1 ethanolamine kinase 1 decreases expression ISO Isotretinoin results in decreased expression of ETNK1 mRNA CTD PMID:20436886 NCBI chr 4:176,126,056...176,170,325
Ensembl chr 4:176,126,180...176,193,770 		JBrowse link
G Exoc7 exocyst complex component 7 decreases expression ISO Isotretinoin results in decreased expression of EXO70 mRNA CTD PMID:20436886 NCBI chr10:101,521,640...101,563,123
Ensembl chr10:101,520,927...101,540,561 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 decreases expression ISO Isotretinoin results in decreased expression of EYA1 mRNA CTD PMID:31711903 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483 		JBrowse link
G Fa2h fatty acid 2-hydroxylase decreases expression ISO Isotretinoin results in decreased expression of FA2H mRNA CTD PMID:20436886 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153 		JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression EXP Isotretinoin results in increased expression of FABP4 mRNA CTD PMID:19212007 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression ISO Isotretinoin results in decreased expression of FABP5 mRNA CTD PMID:15982314 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773 		JBrowse link
G Fabp6 fatty acid binding protein 6 decreases expression ISO Isotretinoin results in decreased expression of FABP6 mRNA CTD PMID:20436886 NCBI chr10:28,063,603...28,068,276
Ensembl chr10:28,063,603...28,068,282 		JBrowse link
G Fabp7 fatty acid binding protein 7 decreases expression ISO Isotretinoin results in decreased expression of FABP7 mRNA CTD PMID:20436886 NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880 		JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression ISO Isotretinoin results in decreased expression of FADS1 mRNA CTD PMID:20436886 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734 		JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression ISO Isotretinoin results in decreased expression of FADS2 mRNA CTD PMID:20436886 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789 		JBrowse link
G Fam149a family with sequence similarity 149, member A increases expression ISO Isotretinoin results in increased expression of FAM149A mRNA CTD PMID:20436886 NCBI chr16:46,855,377...46,914,553
Ensembl chr16:46,854,635...46,912,066 		JBrowse link
G Fam3c FAM3 metabolism regulating signaling molecule C increases expression
decreases expression		 ISO Isotretinoin results in increased expression of FAM3C mRNA
Isotretinoin results in decreased expression of FAM3C mRNA		 CTD PMID:15982314 PMID:20436886 NCBI chr 4:50,839,929...50,887,276
Ensembl chr 4:50,838,818...50,888,078 		JBrowse link
G Far2 fatty acyl CoA reductase 2 decreases expression ISO Isotretinoin results in decreased expression of FAR2 mRNA CTD PMID:20436886 NCBI chr 4:180,973,968...181,087,862
Ensembl chr 4:181,007,622...181,087,255 		JBrowse link
G Fasn fatty acid synthase decreases expression ISO Isotretinoin results in decreased expression of FASN mRNA CTD PMID:15982314 PMID:20436886 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fastk Fas-activated serine/threonine kinase decreases expression ISO Isotretinoin results in decreased expression of FASTK mRNA CTD PMID:15982314 NCBI chr 4:10,732,273...10,736,332
Ensembl chr 4:10,732,256...10,737,430 		JBrowse link
G Fbln1 fibulin 1 increases expression ISO Isotretinoin results in increased expression of FBLN1 mRNA CTD PMID:20436886 NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075 		JBrowse link
G Fbp1 fructose-bisphosphatase 1 decreases expression ISO Isotretinoin results in decreased expression of FBP1 mRNA CTD PMID:20436886 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071 		JBrowse link
G Fbp2 fructose-bisphosphatase 2 decreases expression ISO Isotretinoin results in decreased expression of FBP2 mRNA CTD PMID:20436886 NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698 		JBrowse link
G Fbxl7 F-box and leucine-rich repeat protein 7 increases expression ISO Isotretinoin results in increased expression of FBXL7 mRNA CTD PMID:20436886 NCBI chr 2:77,139,775...77,509,223
Ensembl chr 2:77,140,826...77,509,223 		JBrowse link
G Fbxo9 f-box protein 9 decreases expression ISO Isotretinoin results in decreased expression of FBXO9 mRNA CTD PMID:20436886 NCBI chr 8:78,958,482...78,984,015
Ensembl chr 8:78,958,483...78,983,949 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression ISO Isotretinoin results in decreased expression of FDFT1 mRNA CTD PMID:20436886 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression ISO Isotretinoin results in decreased expression of FDPS mRNA CTD PMID:20436886 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G Fez2 fasciculation and elongation protein zeta 2 increases expression ISO Isotretinoin results in increased expression of FEZ2 mRNA CTD PMID:20436886 NCBI chr 6:16,654,572...16,694,628
Ensembl chr 6:16,654,614...16,694,626 		JBrowse link
G Fgf1 fibroblast growth factor 1 decreases expression ISO Isotretinoin results in decreased expression of FGF1 mRNA CTD PMID:15982314 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 increases expression ISO Isotretinoin results in increased expression of FGFR1 mRNA CTD PMID:20436886 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 increases expression ISO Isotretinoin results in increased expression of FGFR3 mRNA CTD PMID:20436886 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Fh fumarate hydratase decreases expression ISO Isotretinoin results in decreased expression of FH mRNA CTD PMID:20436886 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
G Fkbp10 FKBP prolyl isomerase 10 increases expression ISO Isotretinoin results in increased expression of FKBP10 mRNA CTD PMID:20436886 NCBI chr10:85,345,434...85,357,998
Ensembl chr10:85,346,126...85,427,330 		JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 decreases expression ISO Isotretinoin results in decreased expression of FKBP8 mRNA CTD PMID:15982314 NCBI chr16:18,895,608...18,902,648
Ensembl chr16:18,893,576...18,902,612 		JBrowse link
G Flg filaggrin decreases expression ISO Isotretinoin results in decreased expression of FLG mRNA CTD PMID:15982314 NCBI chr 2:178,888,688...178,912,731 JBrowse link
G Flna filamin A increases expression ISO Isotretinoin results in increased expression of FLNA mRNA CTD PMID:20436886 NCBI chr  X:152,007,758...152,034,266
Ensembl chr  X:152,007,758...152,031,052 		JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand increases expression ISO Isotretinoin results in increased expression of FLT3LG mRNA CTD PMID:20436886 NCBI chr 1:95,615,056...95,620,463
Ensembl chr 1:95,609,370...95,620,463 		JBrowse link
G Fn1 fibronectin 1 increases expression ISO Isotretinoin results in increased expression of FN1 mRNA CTD PMID:20436886 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Isotretinoin affects the localization of and results in decreased activity of FOS protein CTD PMID:18652567 PMID:19066126 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Isotretinoin results in decreased expression of FOSB mRNA CTD PMID:20436886 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Foxc2 forkhead box C2 decreases expression ISO Isotretinoin results in decreased expression of FOXC2 mRNA CTD PMID:31711903 NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737 		JBrowse link
G Foxd1 forkhead box D1 increases expression ISO Isotretinoin results in increased expression of FOXD1 mRNA CTD PMID:20436886 NCBI chr 2:29,702,558...29,704,978
Ensembl chr 2:29,702,558...29,704,978 		JBrowse link
G Fut8 fucosyltransferase 8 increases expression ISO Isotretinoin results in increased expression of FUT8 mRNA CTD PMID:20436886 NCBI chr 6:95,948,230...96,176,677
Ensembl chr 6:95,949,991...96,176,677 		JBrowse link
G Fyb1 FYN binding protein 1 increases expression ISO Isotretinoin results in increased expression of FYB1 mRNA CTD PMID:18769122 NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629 		JBrowse link
G Fzd5 frizzled class receptor 5 decreases expression ISO Isotretinoin results in decreased expression of FZD5 mRNA CTD PMID:20436886 NCBI chr 9:66,117,370...66,119,127
Ensembl chr 9:66,113,112...66,121,457 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases expression
increases expression
multiple interactions		 ISO Isotretinoin results in decreased expression of G6PD mRNA
Isotretinoin results in increased expression of G6PD mRNA
Isotretinoin inhibits the reaction [Benzoyl Peroxide results in decreased activity of G6PD protein]		 CTD PMID:15225900 PMID:15982314 PMID:20436886 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 decreases expression ISO Isotretinoin results in decreased expression of GABRA4 mRNA CTD PMID:20436886 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844 		JBrowse link
G Gal galanin and GMAP prepropeptide decreases expression ISO Isotretinoin results in decreased expression of GAL mRNA CTD PMID:20436886 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959 		JBrowse link
G Gata3 GATA binding protein 3 multiple interactions ISO [vorinostat co-treated with Isotretinoin] results in increased expression of GATA3 mRNA CTD PMID:18769122 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Gatd3a glutamine amidotransferase class 1 domain containing 3A decreases expression ISO Isotretinoin results in decreased expression of GATD3 mRNA CTD PMID:20436886 NCBI chr20:10,514,793...10,522,894
Ensembl chr20:10,514,744...10,522,885 		JBrowse link
G Gba glucosylceramidase beta decreases expression ISO Isotretinoin results in decreased expression of GBA1 mRNA CTD PMID:15982314 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 decreases expression ISO Isotretinoin results in decreased expression of GBE1 mRNA CTD PMID:20436886 NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit decreases expression ISO Isotretinoin results in decreased expression of GCLM mRNA CTD PMID:20436886 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO Isotretinoin results in increased expression of GCNT3 mRNA CTD PMID:18769122 NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562 		JBrowse link
G Gcsh glycine cleavage system protein H decreases expression ISO Isotretinoin results in decreased expression of GCSH mRNA CTD PMID:20436886 NCBI chr19:45,036,013...45,046,770
Ensembl chr19:45,036,011...45,046,792 		JBrowse link
G Gdap1l1 ganglioside-induced differentiation-associated protein 1-like 1 decreases expression ISO Isotretinoin results in decreased expression of GDAP1L1 mRNA CTD PMID:20436886 NCBI chr 3:152,110,225...152,129,693
Ensembl chr 3:152,110,253...152,128,711 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Isotretinoin results in increased expression of GDF15 mRNA CTD PMID:15982314 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gdf2 growth differentiation factor 2 increases expression ISO Isotretinoin results in increased expression of GDF2 mRNA CTD PMID:15982314 NCBI chr16:9,255,430...9,261,429
Ensembl chr16:9,255,430...9,261,429 		JBrowse link
G Ggcx gamma-glutamyl carboxylase decreases expression ISO Isotretinoin results in decreased expression of GGCX mRNA CTD PMID:20436886 NCBI chr 4:104,469,737...104,485,631
Ensembl chr 4:104,469,765...104,487,063 		JBrowse link
G Ggps1 geranylgeranyl diphosphate synthase 1 decreases expression ISO Isotretinoin results in decreased expression of GGPS1 mRNA CTD PMID:20436886 NCBI chr17:51,263,262...51,282,471
Ensembl chr17:51,263,263...51,276,220 		JBrowse link
G Ghitm growth hormone inducible transmembrane protein decreases expression ISO Isotretinoin results in decreased expression of GHITM mRNA CTD PMID:20436886 NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,885,553...12,897,879 		JBrowse link
G Gins1 GINS complex subunit 1 decreases expression ISO Isotretinoin results in decreased expression of GINS1 mRNA CTD PMID:20436886 NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936 		JBrowse link
G Gk glycerol kinase decreases expression ISO Isotretinoin results in decreased expression of GK mRNA CTD PMID:20436886 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631 		JBrowse link
G Gldc glycine decarboxylase decreases expression ISO Isotretinoin results in decreased expression of GLDC mRNA CTD PMID:20436886 NCBI chr 1:227,883,247...227,962,119
Ensembl chr 1:227,883,249...227,962,097 		JBrowse link
G Glrx2 glutaredoxin 2 decreases expression ISO Isotretinoin results in decreased expression of GLRX2 mRNA CTD PMID:20436886 NCBI chr13:55,481,875...55,504,737
Ensembl chr13:55,482,694...55,492,831 		JBrowse link
G Glrx5 glutaredoxin 5 decreases expression ISO Isotretinoin results in decreased expression of GLRX5 mRNA CTD PMID:20436886 NCBI chr 6:123,988,169...123,998,545
Ensembl chr 6:123,988,134...123,998,545 		JBrowse link
G Glul glutamate-ammonia ligase increases expression ISO Isotretinoin results in increased expression of GLUL mRNA CTD PMID:15982314 NCBI chr13:65,969,064...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Gng4 G protein subunit gamma 4 decreases expression ISO Isotretinoin results in decreased expression of GNG4 mRNA CTD PMID:20436886 NCBI chr17:86,448,708...86,497,560
Ensembl chr17:86,449,022...86,495,254 		JBrowse link
G Gnpat glyceronephosphate O-acyltransferase decreases expression ISO Isotretinoin results in decreased expression of GNPAT mRNA CTD PMID:20436886 NCBI chr19:52,822,326...52,848,872
Ensembl chr19:52,822,319...52,852,361 		JBrowse link
G Gpr143 G protein-coupled receptor 143 decreases expression ISO Isotretinoin results in decreased expression of GPR143 mRNA CTD PMID:20436886 NCBI chr  X:22,002,914...22,027,720
Ensembl chr  X:22,002,914...22,027,715 		JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO Isotretinoin results in increased expression of GPX2 mRNA CTD PMID:15623509 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877 		JBrowse link
G Gpx3 glutathione peroxidase 3 decreases expression ISO Isotretinoin results in decreased expression of GPX3 mRNA CTD PMID:20436886 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Grb7 growth factor receptor bound protein 7 decreases expression ISO Isotretinoin results in decreased expression of GRB7 mRNA CTD PMID:15982314 NCBI chr10:83,443,387...83,453,057
Ensembl chr10:83,444,004...83,453,052 		JBrowse link
G Grpel1 GrpE-like 1, mitochondrial decreases expression ISO Isotretinoin results in decreased expression of GRPEL1 mRNA CTD PMID:20436886 NCBI chr14:74,292,023...74,298,243
Ensembl chr14:74,292,023...74,298,200 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO Isotretinoin inhibits the reaction [Benzoyl Peroxide results in decreased activity of GSR protein] CTD PMID:15225900 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases expression ISO Isotretinoin results in decreased expression of GSTM1 mRNA CTD PMID:15982314 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
affects metabolic processing		 ISO Ethacrynic Acid inhibits the reaction [GSTP1 protein affects the metabolism of Isotretinoin]; S-decylglutathione inhibits the reaction [GSTP1 protein affects the metabolism of Isotretinoin] CTD PMID:9806904 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gstz1 glutathione S-transferase zeta 1 decreases expression ISO Isotretinoin results in decreased expression of GSTZ1 mRNA CTD PMID:20436886 NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284 		JBrowse link
G H1f2 H1.2 linker histone, cluster member decreases expression ISO Isotretinoin results in decreased expression of H1-2 mRNA CTD PMID:20436886 NCBI chr17:41,391,106...41,392,611
Ensembl chr17:41,388,477...41,392,635 		JBrowse link
G H2ac25 H2A clustered histone 25 decreases expression ISO Isotretinoin results in decreased expression of H2AC25 mRNA CTD PMID:20436886 NCBI chr10:43,733,702...43,735,254
Ensembl chr10:43,733,668...43,744,874 		JBrowse link
G H2ax H2A.X variant histone decreases expression ISO Isotretinoin results in decreased expression of H2AX mRNA CTD PMID:20436886 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G H2bc12 H2B clustered histone 12 decreases expression ISO Isotretinoin results in decreased expression of H2BC12 mRNA CTD PMID:20436886 NCBI chr17:42,485,746...42,486,126 JBrowse link
G H2bc6 H2B clustered histone 6 decreases expression ISO Isotretinoin results in decreased expression of H2BC6 mRNA CTD PMID:20436886 NCBI chr17:41,520,767...41,521,240 JBrowse link
G H2bc9 H2B clustered histone 9 decreases expression ISO Isotretinoin results in decreased expression of H2BC9 mRNA CTD PMID:20436886 NCBI chr17:42,470,593...42,478,605 JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase decreases expression ISO Isotretinoin results in decreased expression of HADH mRNA CTD PMID:20436886 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353 		JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression ISO Isotretinoin results in decreased expression of HAO2 mRNA CTD PMID:20436886 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Isotretinoin results in increased expression of HBEGF mRNA CTD PMID:15982314 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Hcls1 hematopoietic cell specific Lyn substrate 1 increases expression ISO Isotretinoin results in increased expression of HCLS1 mRNA CTD PMID:20436886 NCBI chr11:63,817,482...63,840,943
Ensembl chr11:63,817,476...63,841,014 		JBrowse link
G Hcn3 hyperpolarization-activated cyclic nucleotide-gated potassium channel 3 decreases expression ISO Isotretinoin results in decreased expression of HCN3 mRNA CTD PMID:20436886 NCBI chr 2:174,551,866...174,567,459
Ensembl chr 2:174,551,680...174,565,966 		JBrowse link
G Hgd homogentisate 1, 2-dioxygenase decreases expression ISO Isotretinoin results in decreased expression of HGD mRNA CTD PMID:20436886 NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323 		JBrowse link
G Hgf hepatocyte growth factor decreases expression
decreases secretion		 ISO Isotretinoin results in decreased expression of HGF mRNA
Isotretinoin results in decreased secretion of HGF protein		 CTD PMID:11223164 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase decreases expression ISO Isotretinoin results in decreased expression of HIBCH mRNA CTD PMID:20436886 NCBI chr 9:48,590,097...48,669,896
Ensembl chr 9:48,590,099...48,669,824 		JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated decreases expression ISO Isotretinoin results in decreased expression of HILPDA mRNA CTD PMID:20436886 NCBI chr 4:57,871,076...57,875,206
Ensembl chr 4:57,871,110...57,874,557 		JBrowse link
G Hip1 huntingtin interacting protein 1 increases expression ISO Isotretinoin results in increased expression of HIP1 mRNA CTD PMID:20436886 NCBI chr12:21,133,319...21,267,796
Ensembl chr12:21,133,406...21,267,725 		JBrowse link
G Hist1h2af histone cluster 1 H2A family member F decreases expression ISO Isotretinoin results in decreased expression of H2AC8 mRNA CTD PMID:20436886 NCBI chr17:41,379,404...41,379,796
Ensembl chr17:41,379,404...41,379,796 		JBrowse link
G Hist1h2ah histone cluster 1 H2A family member H decreases expression ISO Isotretinoin results in decreased expression of H2AC11 mRNA CTD PMID:20436886 NCBI chr17:41,384,521...41,385,018 JBrowse link
G Hist1h2bc histone cluster 1, H2bc decreases expression ISO Isotretinoin results in decreased expression of H2BC4 mRNA CTD PMID:20436886 NCBI chr17:42,692,335...42,696,860
Ensembl chr17:42,694,723...42,696,642 		JBrowse link
G Hist1h2bd histone cluster 1 H2B family member D decreases expression ISO Isotretinoin results in decreased expression of H2BC5 mRNA CTD PMID:20436886 NCBI chr17:42,792,887...42,793,268 JBrowse link
G Hlcs holocarboxylase synthetase decreases expression ISO Isotretinoin results in decreased expression of HLCS mRNA CTD PMID:20436886 NCBI chr11:33,455,806...33,635,197
Ensembl chr11:33,455,809...33,624,222 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO Isotretinoin results in decreased expression of HMGCR mRNA CTD PMID:20436886 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO Isotretinoin results in decreased expression of HMGCS1 mRNA CTD PMID:20436886 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression ISO Isotretinoin results in decreased expression of HSD11B1 mRNA CTD PMID:15982314 PMID:20436886 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687 		JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 decreases expression ISO Isotretinoin results in decreased expression of HSD17B12 mRNA CTD PMID:20436886 NCBI chr 3:79,990,048...80,113,556
Ensembl chr 3:79,990,056...80,113,617 		JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 decreases expression ISO Isotretinoin results in decreased expression of HSD17B7 mRNA CTD PMID:20436886 NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO Isotretinoin results in decreased expression of HSD3B1 mRNA CTD PMID:20436886 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 decreases expression ISO Isotretinoin results in decreased expression of HSP90B1 mRNA CTD PMID:20436886 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788 		JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 decreases expression ISO Isotretinoin results in decreased expression of HSPA9 mRNA CTD PMID:20436886 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression ISO Isotretinoin results in decreased expression of HSPD1 mRNA CTD PMID:20436886 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A decreases expression ISO Isotretinoin results in decreased expression of HTR1A protein CTD PMID:27606422 NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B decreases expression ISO Isotretinoin results in decreased expression of HTR1B protein CTD PMID:27606422 NCBI chr 8:82,513,572...82,534,892
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Htra1 HtrA serine peptidase 1 increases expression ISO Isotretinoin results in increased expression of HTRA1 mRNA CTD PMID:20436886 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379 		JBrowse link
G Hus1 HUS1 checkpoint clamp component decreases expression ISO Isotretinoin results in decreased expression of HUS1 mRNA CTD PMID:20436886 NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442 		JBrowse link
G Icam2 intercellular adhesion molecule 2 increases expression ISO Isotretinoin results in increased expression of ICAM2 mRNA CTD PMID:20436886 NCBI chr10:91,308,608...91,319,536
Ensembl chr10:91,308,538...91,315,293 		JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 decreases expression ISO Isotretinoin results in decreased expression of IDH1 mRNA CTD PMID:20436886 NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO Isotretinoin results in decreased expression of IDI1 mRNA CTD PMID:20436886 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357 		JBrowse link
G Ier3 immediate early response 3 decreases expression ISO Isotretinoin results in decreased expression of IER3 mRNA CTD PMID:20436886 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Ifi35 interferon-induced protein 35 increases expression ISO Isotretinoin results in increased expression of IFI35 mRNA CTD PMID:20436886 NCBI chr10:86,381,023...86,389,279
Ensembl chr10:86,381,010...86,389,952 		JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 increases expression ISO Isotretinoin results in increased expression of IFITM1 mRNA CTD PMID:20436886 NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169 		JBrowse link
G Ifrd1 interferon-related developmental regulator 1 decreases expression ISO Isotretinoin results in decreased expression of IFRD1 mRNA CTD PMID:20436886 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990 		JBrowse link
G Ift20 intraflagellar transport 20 decreases expression ISO Isotretinoin results in decreased expression of IFT20 mRNA CTD PMID:20436886 NCBI chr10:63,432,597...63,438,125
Ensembl chr10:63,432,633...63,438,124 		JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO Isotretinoin results in increased expression of IGF1 mRNA CTD PMID:15982314 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression ISO Isotretinoin results in increased expression of IGFBP3 mRNA CTD PMID:18769122 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 increases expression ISO Isotretinoin results in increased expression of IGFBP4 mRNA CTD PMID:20436886 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 increases expression ISO Isotretinoin results in increased expression of IGFBP5 mRNA CTD PMID:20436886 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156 		JBrowse link
G Il10 interleukin 10 decreases expression
decreases secretion		 EXP Isotretinoin results in decreased expression of IL10 mRNA
Isotretinoin results in decreased secretion of IL10 protein		 CTD PMID:15972972 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il10ra interleukin 10 receptor subunit alpha decreases expression ISO Isotretinoin results in decreased expression of IL10RA mRNA CTD PMID:15982314 NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061 		JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 decreases expression ISO Isotretinoin results in decreased expression of IL13RA1 mRNA CTD PMID:20436886 NCBI chr  X:115,348,860...115,408,682
Ensembl chr  X:115,348,860...115,408,681 		JBrowse link
G Il1a interleukin 1 alpha decreases secretion EXP Isotretinoin results in decreased secretion of IL1A protein CTD PMID:15972972 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta decreases expression
increases expression
multiple interactions
decreases secretion		 ISO
EXP		 Isotretinoin results in decreased expression of IL1B mRNA
Isotretinoin results in increased expression of IL1B mRNA
[vorinostat co-treated with Isotretinoin] results in increased expression of IL1B mRNA
Isotretinoin results in decreased secretion of IL1B protein		 CTD PMID:15972972 PMID:15982314 PMID:18769122 PMID:20436886 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 decreases expression ISO Isotretinoin results in decreased expression of IL1R2 mRNA CTD PMID:20436886 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Il2 interleukin 2 decreases secretion EXP Isotretinoin results in decreased secretion of IL2 protein CTD PMID:15972972 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il24 interleukin 24 decreases expression ISO Isotretinoin results in decreased expression of IL24 mRNA CTD PMID:15982314 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Il4 interleukin 4 decreases secretion EXP Isotretinoin results in decreased secretion of IL4 protein CTD PMID:15972972 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 decreases expression
decreases secretion		 ISO
EXP		 Isotretinoin results in decreased expression of IL6 mRNA
Isotretinoin results in decreased secretion of IL6 protein		 CTD PMID:15972972 PMID:17033190 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B decreases expression ISO Isotretinoin results in decreased expression of INPP4B mRNA CTD PMID:20436886 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634 		JBrowse link
G Insig1 insulin induced gene 1 decreases expression ISO Isotretinoin results in decreased expression of INSIG1 mRNA CTD PMID:20436886 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO Isotretinoin promotes the reaction [Dacarbazine results in increased expression of IRF1 mRNA] CTD PMID:17973783 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Isca1 iron-sulfur cluster assembly 1 decreases expression ISO Isotretinoin results in decreased expression of ISCA1 mRNA CTD PMID:20436886 NCBI chr17:4,905,291...4,917,955
Ensembl chr17:4,905,287...4,917,955 		JBrowse link
G Islr immunoglobulin superfamily containing leucine-rich repeat increases expression ISO Isotretinoin results in increased expression of ISLR mRNA CTD PMID:20436886 NCBI chr 8:58,571,155...58,574,128
Ensembl chr 8:58,570,777...58,574,130 		JBrowse link
G Isoc1 isochorismatase domain containing 1 decreases expression ISO Isotretinoin results in decreased expression of ISOC1 mRNA CTD PMID:20436886 NCBI chr18:52,158,790...52,179,206
Ensembl chr18:52,158,790...52,178,703 		JBrowse link
G Itga4 integrin subunit alpha 4 increases expression ISO Isotretinoin results in increased expression of ITGA4 mRNA CTD PMID:15982314 NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715 		JBrowse link
G Itgav integrin subunit alpha V increases expression ISO Isotretinoin results in increased expression of ITGAV mRNA CTD PMID:20436886 NCBI chr 3:68,838,524...68,926,653
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Itgb2 integrin subunit beta 2 increases expression ISO Isotretinoin results in increased expression of ITGB2 mRNA CTD PMID:20436886 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Jak1 Janus kinase 1 increases expression ISO Isotretinoin results in increased expression of JAK1 mRNA CTD PMID:20436886 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Kank2 KN motif and ankyrin repeat domains 2 increases expression ISO Isotretinoin results in increased expression of KANK2 mRNA CTD PMID:20436886 NCBI chr 8:20,311,676...20,341,107
Ensembl chr 8:20,311,676...20,340,900 		JBrowse link
G Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 decreases expression ISO Isotretinoin results in decreased expression of KCNJ15 mRNA CTD PMID:20436886 NCBI chr11:34,577,397...34,621,725
Ensembl chr11:34,577,363...34,621,952 		JBrowse link
G Kcnk1 potassium two pore domain channel subfamily K member 1 decreases expression ISO Isotretinoin results in decreased expression of KCNK1 mRNA CTD PMID:20436886 NCBI chr19:53,959,411...53,997,726
Ensembl chr19:53,959,657...53,997,724 		JBrowse link
G Kctd12 potassium channel tetramerization domain containing 12 increases expression ISO Isotretinoin results in increased expression of KCTD12 mRNA CTD PMID:20436886 NCBI chr15:79,800,077...79,806,064
Ensembl chr15:79,801,191...79,806,282 		JBrowse link
G Klhdc4 kelch domain containing 4 decreases expression ISO Isotretinoin results in decreased expression of KLHDC4 mRNA CTD PMID:20436886 NCBI chr19:49,860,975...49,894,027
Ensembl chr19:49,860,967...49,894,868 		JBrowse link
G Kras KRAS proto-oncogene, GTPase decreases expression ISO Isotretinoin results in decreased expression of KRAS mRNA CTD PMID:20436886 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Krt1 keratin 1 decreases expression ISO Isotretinoin results in decreased expression of KRT1 mRNA CTD PMID:15982314 NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844 		JBrowse link
G Krt10 keratin 10 decreases expression ISO Isotretinoin results in decreased expression of KRT10 mRNA CTD PMID:15982314 NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701 		JBrowse link
G Krt14 keratin 14 decreases expression ISO Isotretinoin results in decreased expression of KRT14 mRNA; Isotretinoin results in decreased expression of KRT14 protein CTD PMID:15982314 NCBI chr10:85,137,932...85,141,990
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt15 keratin 15 increases expression ISO Isotretinoin results in increased expression of KRT15 mRNA CTD PMID:15982314 NCBI chr10:85,066,797...85,070,614
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt16 keratin 16 decreases expression ISO Isotretinoin results in decreased expression of KRT16 mRNA CTD PMID:20436886 NCBI chr10:85,168,357...85,171,744
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt17 keratin 17 decreases expression ISO Isotretinoin results in decreased expression of KRT17 mRNA; Isotretinoin results in decreased expression of KRT17 protein CTD PMID:15982314 PMID:18769122 NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392 		JBrowse link
G Krt19 keratin 19 increases expression ISO Isotretinoin results in increased expression of KRT19 mRNA; Isotretinoin results in increased expression of KRT19 protein CTD PMID:15982314 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt5 keratin 5 decreases expression ISO Isotretinoin results in decreased expression of KRT5 mRNA CTD PMID:15982314 NCBI chr 7:132,846,355...132,851,986
Ensembl chr 7:132,846,136...132,851,850 		JBrowse link
G Krt7 keratin 7 increases expression ISO Isotretinoin results in increased expression of KRT7 mRNA; Isotretinoin results in increased expression of KRT7 protein CTD PMID:15982314 NCBI chr 7:132,528,863...132,545,052
Ensembl chr 7:132,528,895...132,545,052 		JBrowse link
G Krt75 keratin 75 decreases expression ISO Isotretinoin results in decreased expression of KRT75 mRNA CTD PMID:15982314 NCBI chr 7:132,687,101...132,697,360
Ensembl chr 7:132,688,237...132,697,345 		JBrowse link
G Lactb2 lactamase, beta 2 decreases expression ISO Isotretinoin results in decreased expression of LACTB2 mRNA CTD PMID:20436886 NCBI chr 5:5,569,080...5,591,843
Ensembl chr 5:5,569,067...5,596,429 		JBrowse link
G Lage3 L antigen family, member 3 decreases expression ISO Isotretinoin results in decreased expression of LAGE3 mRNA CTD PMID:20436886 NCBI chr  X:152,138,209...152,139,632
Ensembl chr  X:152,138,218...152,139,632 		JBrowse link
G Lama2 laminin subunit alpha 2 decreases expression
increases expression		 ISO Isotretinoin results in decreased expression of LAMA2 mRNA
Isotretinoin results in increased expression of LAMA2 mRNA		 CTD PMID:15982314 PMID:20436886 NCBI chr 1:17,672,675...18,320,641
Ensembl chr 1:17,672,536...18,320,530 		JBrowse link
G Lama3 laminin subunit alpha 3 decreases expression ISO Isotretinoin results in decreased expression of LAMA3 mRNA CTD PMID:15982314 NCBI chr18:3,523,168...3,751,722
Ensembl chr18:3,523,133...3,751,353 		JBrowse link
G Lamc1 laminin subunit gamma 1 increases expression ISO Isotretinoin results in increased expression of LAMC1 mRNA CTD PMID:20436886 NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492 		JBrowse link
G Lamc3 laminin subunit gamma 3 increases expression ISO Isotretinoin results in increased expression of LAMC3 mRNA CTD PMID:15982314 NCBI chr 3:15,165,220...15,226,697
Ensembl chr 3:15,165,220...15,226,697 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 increases expression ISO Isotretinoin results in increased expression of LAPTM5 mRNA CTD PMID:20436886 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Larp4 La ribonucleoprotein 4 decreases expression ISO Isotretinoin results in decreased expression of LARP4 mRNA CTD PMID:20436886 NCBI chr 7:131,104,470...131,152,692
Ensembl chr 7:131,101,564...131,150,811 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase increases expression ISO Isotretinoin results in increased expression of LCK mRNA CTD PMID:20436886 NCBI chr 5:141,888,319...141,916,992
Ensembl chr 5:141,888,326...141,903,794 		JBrowse link
G Lcn2 lipocalin 2 increases expression ISO Isotretinoin results in increased expression of LCN2 mRNA CTD PMID:15982314 PMID:18769122 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Lcp2 lymphocyte cytosolic protein 2 increases expression ISO Isotretinoin results in increased expression of LCP2 mRNA CTD PMID:20436886 NCBI chr10:18,642,600...18,689,562
Ensembl chr10:18,642,658...18,689,559 		JBrowse link
G Ldlr low density lipoprotein receptor decreases expression ISO Isotretinoin results in decreased expression of LDLR mRNA CTD PMID:20436886 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lep leptin increases expression EXP Isotretinoin results in increased expression of LEP mRNA CTD PMID:19212007 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lhfpl6 LHFPL tetraspan subfamily member 6 increases expression ISO Isotretinoin results in increased expression of LHFPL6 mRNA CTD PMID:20436886 NCBI chr 2:137,126,485...137,324,442
Ensembl chr 2:137,126,509...137,324,443 		JBrowse link
G Limch1 LIM and calponin homology domains 1 increases expression ISO Isotretinoin results in increased expression of LIMCH1 mRNA CTD PMID:20436886 NCBI chr14:41,112,579...41,425,185
Ensembl chr14:41,114,803...41,425,191 		JBrowse link
G Lipc lipase C, hepatic type increases expression ISO Isotretinoin results in increased expression of LIPC mRNA CTD PMID:20436886 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464 		JBrowse link
G Lmnb1 lamin B1 increases expression ISO Isotretinoin results in increased expression of LMNB1 protein CTD PMID:15982314 NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502 		JBrowse link
G Lmo2 LIM domain only 2 increases expression ISO Isotretinoin results in increased expression of LMO2 mRNA CTD PMID:20436886 NCBI chr 3:90,355,234...90,377,970
Ensembl chr 3:90,365,883...90,377,953 		JBrowse link
G Loxl2 lysyl oxidase-like 2 increases expression ISO Isotretinoin results in increased expression of LOXL2 mRNA CTD PMID:20436886 NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067 		JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 decreases expression ISO Isotretinoin results in decreased expression of LPCAT3 mRNA CTD PMID:20436886 NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880 		JBrowse link
G Lpin1 lipin 1 decreases expression ISO Isotretinoin results in decreased expression of LPIN1 mRNA CTD PMID:20436886 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097 		JBrowse link
G Lrat lecithin retinol acyltransferase increases expression ISO Isotretinoin results in increased expression of LRAT protein CTD PMID:15982314 NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619 		JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 increases expression ISO Isotretinoin results in increased expression of LTBP1 mRNA CTD PMID:20436886 NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase increases expression ISO Isotretinoin results in increased expression of LYN mRNA CTD PMID:20436886 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Maff MAF bZIP transcription factor F decreases expression ISO Isotretinoin results in decreased expression of MAFF mRNA CTD PMID:20436886 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851 		JBrowse link
G Man1a1 mannosidase, alpha, class 1A, member 1 increases expression ISO Isotretinoin results in increased expression of MAN1A1 mRNA CTD PMID:20436886 NCBI chr20:33,202,509...33,385,747
Ensembl chr20:33,202,517...33,385,824 		JBrowse link
G Map4 microtubule-associated protein 4 increases expression ISO Isotretinoin results in increased expression of MAP4 mRNA CTD PMID:20436886 NCBI chr 8:109,925,233...110,064,370
Ensembl chr 8:109,925,575...110,064,362 		JBrowse link
G Mboat2 membrane bound O-acyltransferase domain containing 2 decreases expression ISO Isotretinoin results in decreased expression of MBOAT2 mRNA CTD PMID:20436886 NCBI chr 6:41,471,135...41,597,599
Ensembl chr 6:41,471,161...41,593,485 		JBrowse link
G Mc5r melanocortin 5 receptor decreases expression ISO Isotretinoin results in decreased expression of MC5R mRNA CTD PMID:20436886 NCBI chr18:61,915,188...61,920,229
Ensembl chr18:61,915,188...61,920,229 		JBrowse link
G Mcat malonyl-CoA-acyl carrier protein transacylase decreases expression ISO Isotretinoin results in decreased expression of MCAT mRNA CTD PMID:20436886 NCBI chr 7:114,693,612...114,705,677
Ensembl chr 7:114,693,612...114,704,542 		JBrowse link
G Mccc1 methylcrotonyl-CoA carboxylase subunit 1 decreases expression ISO Isotretinoin results in decreased expression of MCCC1 mRNA CTD PMID:20436886 NCBI chr 2:118,799,147...118,851,181
Ensembl chr 2:118,799,150...118,851,222 		JBrowse link
G Mccc2 methylcrotonyl-CoA carboxylase subunit 2 decreases expression ISO Isotretinoin results in decreased expression of MCCC2 mRNA CTD PMID:20436886 NCBI chr 2:31,304,927...31,375,978
Ensembl chr 2:31,304,932...31,375,972 		JBrowse link
G Mcfd2 multiple coagulation factor deficiency 2 decreases expression ISO Isotretinoin results in decreased expression of MCFD2 mRNA CTD PMID:20436886 NCBI chr 6:7,274,469...7,285,841
Ensembl chr 6:7,274,469...7,285,841 		JBrowse link
G Mcts1 MCTS1, re-initiation and release factor decreases expression ISO Isotretinoin results in decreased expression of MCTS1 mRNA CTD PMID:20436886 NCBI chr  X:117,350,723...117,362,504
Ensembl chr  X:117,350,889...117,362,504 		JBrowse link
G Mcur1 mitochondrial calcium uniporter regulator 1 decreases expression ISO Isotretinoin results in decreased expression of MCUR1 mRNA CTD PMID:20436886 NCBI chr17:21,142,526...21,159,651
Ensembl chr17:21,141,602...21,159,651 		JBrowse link
G Mdh1 malate dehydrogenase 1 decreases expression ISO Isotretinoin results in decreased expression of MDH1 mRNA CTD PMID:20436886 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925 		JBrowse link
G Me1 malic enzyme 1 decreases expression ISO Isotretinoin results in decreased expression of ME1 mRNA CTD PMID:20436886 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Mecr mitochondrial trans-2-enoyl-CoA reductase decreases expression ISO Isotretinoin results in decreased expression of MECR mRNA CTD PMID:20436886 NCBI chr 5:144,029,684...144,056,373
Ensembl chr 5:144,029,731...144,055,863 		JBrowse link
G Med8 mediator complex subunit 8 decreases expression ISO Isotretinoin results in decreased expression of MED8 mRNA CTD PMID:20436886 NCBI chr 5:131,948,632...131,949,516
Ensembl chr 5:131,943,982...131,950,305 		JBrowse link
G Mef2c myocyte enhancer factor 2C increases expression ISO Isotretinoin results in increased expression of MEF2C mRNA CTD PMID:20436886 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Meox1 mesenchyme homeobox 1 decreases expression ISO Isotretinoin results in decreased expression of MEOX1 mRNA CTD PMID:31711903 NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660 		JBrowse link
G Mesp2 mesoderm posterior bHLH transcription factor 2 decreases expression ISO Isotretinoin results in decreased expression of MESP2 mRNA CTD PMID:31711903 NCBI chr 1:133,756,601...133,759,207
Ensembl chr 1:133,756,601...133,759,198 		JBrowse link
G Mfap2 microfibril associated protein 2 decreases expression
increases expression		 ISO Isotretinoin results in decreased expression of MFAP2 mRNA
Isotretinoin results in increased expression of MFAP2 mRNA		 CTD PMID:15982314 PMID:20436886 NCBI chr 5:153,312,068...153,320,266
Ensembl chr 5:153,314,711...153,320,259 		JBrowse link
G Mfap3l microfibril associated protein 3 like decreases expression ISO Isotretinoin results in decreased expression of MFAP3L mRNA CTD PMID:20436886 NCBI chr16:29,411,643...29,454,665
Ensembl chr16:29,415,849...29,430,863 		JBrowse link
G Mfap4 microfibril associated protein 4 increases expression ISO Isotretinoin results in increased expression of MFAP4 mRNA CTD PMID:20436886 NCBI chr10:46,167,158...46,170,176
Ensembl chr10:46,167,217...46,170,155 		JBrowse link
G Mlana melan-A decreases expression ISO Isotretinoin results in decreased expression of MLANA mRNA CTD PMID:20436886 NCBI chr 1:227,469,537...227,483,343
Ensembl chr 1:227,469,537...227,483,343 		JBrowse link
G Mmp10 matrix metallopeptidase 10 decreases expression ISO Isotretinoin results in decreased expression of MMP10 mRNA CTD PMID:15982314 NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748 		JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions
decreases expression		 ISO Isotretinoin inhibits the reaction [Arachidonic Acid results in increased expression of MMP13 mRNA]; Isotretinoin inhibits the reaction [Arachidonic Acid results in increased secretion of MMP13 protein]
Isotretinoin results in decreased expression of MMP13 protein		 CTD PMID:16185265 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression		 ISO Isotretinoin inhibits the reaction [Arachidonic Acid results in increased expression of MMP2 mRNA]; Isotretinoin inhibits the reaction [Arachidonic Acid results in increased secretion of MMP2 protein]
Isotretinoin results in increased expression of MMP2 mRNA		 CTD PMID:16185265 PMID:20436886 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp23 matrix metallopeptidase 23 increases expression ISO Isotretinoin results in increased expression of MMP23B mRNA CTD PMID:20436886 NCBI chr 5:166,239,643...166,242,734
Ensembl chr 5:166,239,644...166,242,433 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression		 ISO Isotretinoin inhibits the reaction [Arachidonic Acid results in increased expression of MMP9 mRNA]; Isotretinoin inhibits the reaction [Arachidonic Acid results in increased secretion of MMP9 protein]
Isotretinoin results in decreased expression of MMP9 protein		 CTD PMID:16185265 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mocos molybdenum cofactor sulfurase decreases expression ISO Isotretinoin results in decreased expression of MOCOS mRNA CTD PMID:20436886 NCBI chr18:15,931,654...15,977,415
Ensembl chr18:15,931,654...15,977,187 		JBrowse link
G Mospd1 motile sperm domain containing 1 decreases expression ISO Isotretinoin results in decreased expression of MOSPD1 mRNA CTD PMID:20436886 NCBI chr  X:133,100,200...133,127,960
Ensembl chr  X:133,100,422...133,127,908
Ensembl chr 1:133,100,422...133,127,908 		JBrowse link
G Mpc1 mitochondrial pyruvate carrier 1 decreases expression ISO Isotretinoin results in decreased expression of MPC1 mRNA CTD PMID:20436886 NCBI chr 1:52,437,745...52,449,369
Ensembl chr 1:52,437,741...52,449,400 		JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 decreases expression ISO Isotretinoin results in decreased expression of MPC2 mRNA CTD PMID:20436886 NCBI chr13:77,728,176...77,747,664
Ensembl chr13:77,728,250...77,747,664 		JBrowse link
G Mrpl33 mitochondrial ribosomal protein L33 decreases expression ISO Isotretinoin results in decreased expression of MRPL33 mRNA CTD PMID:20436886 NCBI chr 6:24,825,804...24,834,061
Ensembl chr 6:24,825,827...24,833,834 		JBrowse link
G Mrps16 mitochondrial ribosomal protein S16 decreases expression ISO Isotretinoin results in decreased expression of MRPS16 mRNA CTD PMID:20436886 NCBI chr15:3,918,621...3,921,024
Ensembl chr15:3,918,615...3,921,656 		JBrowse link
G Mrps18a mitochondrial ribosomal protein S18A decreases expression ISO Isotretinoin results in decreased expression of MRPS18A mRNA CTD PMID:20436886 NCBI chr 9:14,853,322...14,869,819
Ensembl chr 9:14,853,291...14,869,835 		JBrowse link
G Mrps33 mitochondrial ribosomal protein S33 decreases expression ISO Isotretinoin results in decreased expression of MRPS33 mRNA CTD PMID:20436886 NCBI chr 4:68,596,729...68,605,547
Ensembl chr 4:68,596,729...68,605,428 		JBrowse link
G Mrs2 magnesium transporter MRS2 decreases expression ISO Isotretinoin results in decreased expression of MRS2 mRNA CTD PMID:20436886 NCBI chr17:40,063,924...40,087,073
Ensembl chr17:40,063,962...40,081,887 		JBrowse link
G Mrtfb myocardin related transcription factor B increases expression ISO Isotretinoin results in increased expression of MRTFB mRNA CTD PMID:20436886 NCBI chr10:1,116,315...1,278,106
Ensembl chr10:1,116,310...1,277,897 		JBrowse link
G Msmb microseminoprotein, beta increases expression ISO Isotretinoin results in increased expression of MSMB mRNA CTD PMID:20436886 NCBI chr16:7,366,536...7,387,124
Ensembl chr16:7,366,536...7,387,123 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases expression ISO Isotretinoin results in decreased expression of MSMO1 mRNA CTD PMID:20436886 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016 		JBrowse link
G Msrb1 methionine sulfoxide reductase B1 decreases expression ISO Isotretinoin results in decreased expression of MSRB1 mRNA CTD PMID:20436886 NCBI chr10:13,764,883...13,770,609
Ensembl chr10:13,764,883...13,770,609 		JBrowse link
G Mtch2 mitochondrial carrier 2 decreases expression ISO Isotretinoin results in decreased expression of MTCH2 mRNA CTD PMID:20436886 NCBI chr 3:76,830,549...76,850,189
Ensembl chr 3:76,830,413...76,850,189 		JBrowse link
G Mto1 mitochondrial tRNA translation optimization 1 decreases expression ISO Isotretinoin results in decreased expression of MTO1 mRNA CTD PMID:20436886 NCBI chr 8:79,309,681...79,335,231
Ensembl chr 8:79,309,982...79,335,231 		JBrowse link
G Mtx1 Metaxin 1 decreases expression ISO Isotretinoin results in decreased expression of MTX1 mRNA CTD PMID:20436886 NCBI chr 2:174,615,460...174,621,383
Ensembl chr 2:174,615,461...174,620,982 		JBrowse link
G Muc1 mucin 1, cell surface associated decreases expression ISO Isotretinoin results in decreased expression of MUC1 mRNA CTD PMID:20436886 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Mvd mevalonate diphosphate decarboxylase decreases expression ISO Isotretinoin results in decreased expression of MVD mRNA CTD PMID:20436886 NCBI chr19:50,496,366...50,506,389
Ensembl chr19:50,496,367...50,507,971 		JBrowse link
G Mvk mevalonate kinase decreases expression ISO Isotretinoin results in decreased expression of MVK mRNA CTD PMID:20436886 NCBI chr12:42,141,391...42,158,858
Ensembl chr12:42,141,384...42,158,882 		JBrowse link
G Mycbp Myc binding protein decreases expression ISO Isotretinoin results in decreased expression of MYCBP mRNA CTD PMID:20436886 NCBI chr 5:136,135,955...136,143,163
Ensembl chr 5:136,135,931...136,145,616 		JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor decreases expression
multiple interactions		 ISO Isotretinoin results in decreased expression of MYCN mRNA
R116010 promotes the reaction [Isotretinoin results in decreased expression of MYCN mRNA]		 CTD PMID:17486130 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590 		JBrowse link
G Myl4 myosin, light chain 4 decreases expression ISO Isotretinoin results in decreased expression of MYL4 mRNA CTD PMID:20436886 NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363 		JBrowse link
G Myod1 myogenic differentiation 1 decreases expression ISO Isotretinoin results in decreased expression of MYOD1 mRNA CTD PMID:20436886 NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554 		JBrowse link
G Nadk NAD kinase decreases expression ISO Isotretinoin results in decreased expression of NADK mRNA CTD PMID:20436886 NCBI chr 5:166,145,708...166,176,328
Ensembl chr 5:166,145,481...166,176,322 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase decreases expression ISO Isotretinoin results in decreased expression of NAMPT mRNA CTD PMID:20436886 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100 		JBrowse link
G Nbn nibrin decreases expression ISO Isotretinoin results in decreased expression of NBN mRNA CTD PMID:20436886 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Ndufa3 NADH:ubiquinone oxidoreductase subunit A3 decreases expression ISO Isotretinoin results in decreased expression of NDUFA3 mRNA CTD PMID:20436886 NCBI chr 1:65,597,562...65,600,242
Ensembl chr 1:65,597,578...65,600,235 		JBrowse link
G Ndufaf1 NADH:ubiquinone oxidoreductase complex assembly factor 1 decreases expression ISO Isotretinoin results in decreased expression of CIA30 mRNA CTD PMID:20436886 NCBI chr 3:106,639,025...106,650,549
Ensembl chr 3:106,639,851...106,650,212 		JBrowse link
G Ndufb3 NADH:ubiquinone oxidoreductase subunit B3 decreases expression ISO Isotretinoin results in decreased expression of NDUFB3 mRNA CTD PMID:20436886 NCBI chr 9:60,129,240...60,139,452
Ensembl chr 9:60,129,154...60,139,446 		JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 decreases expression ISO Isotretinoin results in decreased expression of NDUFC2 mRNA CTD PMID:20436886 NCBI chr 1:151,711,965...151,718,188
Ensembl chr 1:151,711,901...151,718,189 		JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 decreases expression ISO Isotretinoin results in decreased expression of NDUFS1 mRNA CTD PMID:20436886 NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893 		JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 decreases expression ISO Isotretinoin results in decreased expression of NDUFS3 mRNA CTD PMID:20436886 NCBI chr 3:76,876,646...76,883,824
Ensembl chr 3:76,876,646...76,883,824 		JBrowse link
G Ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 decreases expression ISO Isotretinoin results in decreased expression of NDUFS7 mRNA CTD PMID:20436886 NCBI chr 7:9,452,556...9,460,135
Ensembl chr 7:9,450,392...9,460,195 		JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 decreases expression ISO Isotretinoin results in decreased expression of NDUFS8 mRNA CTD PMID:20436886 NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511 		JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 decreases expression ISO Isotretinoin results in decreased expression of NDUFV2 mRNA CTD PMID:20436886 NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:105,690,455...105,710,713 		JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 increases expression ISO Isotretinoin results in increased expression of NEDD9 mRNA CTD PMID:15982314 NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019 		JBrowse link
G Nefl neurofilament light chain decreases expression ISO Isotretinoin results in decreased expression of NEFL mRNA CTD PMID:15982314 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793 		JBrowse link
G Neurog2 neurogenin 2 increases expression ISO Isotretinoin results in increased expression of NEUROG2 mRNA CTD PMID:31711903 NCBI chr 2:216,092,641...216,095,276
Ensembl chr 2:216,093,363...216,094,154 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Isotretinoin affects the localization of and results in decreased activity of NFKB1 protein CTD PMID:18652567 PMID:19066126 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nit2 nitrilase family, member 2 decreases expression ISO Isotretinoin results in decreased expression of NIT2 mRNA CTD PMID:20436886 NCBI chr11:43,363,839...43,378,713
Ensembl chr11:43,363,985...43,375,024 		JBrowse link
G Nop16 NOP16 nucleolar protein decreases expression ISO Isotretinoin results in decreased expression of NOP16 mRNA CTD PMID:20436886 NCBI chr17:10,022,950...10,027,867
Ensembl chr17:10,022,932...10,027,867 		JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 decreases expression ISO Isotretinoin results in decreased expression of NPC1 mRNA CTD PMID:20436886 NCBI chr18:3,379,482...3,425,100
Ensembl chr18:3,379,482...3,425,049 		JBrowse link
G Npl N-acetylneuraminate pyruvate lyase decreases expression ISO Isotretinoin results in decreased expression of NPL mRNA CTD PMID:20436886 NCBI chr13:65,655,099...65,697,464
Ensembl chr13:65,655,118...65,697,372 		JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 decreases expression ISO Isotretinoin results in decreased expression of NQO2 mRNA CTD PMID:20436886 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Isotretinoin inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]; Isotretinoin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity		 ISO [Isotretinoin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; Isotretinoin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA] CTD PMID:16632523 PMID:25455453 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 increases expression ISO Isotretinoin results in increased expression of NR2F1 mRNA CTD PMID:20436886 NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123 		JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like decreases expression ISO Isotretinoin results in decreased expression of NSDHL mRNA CTD PMID:20436886 NCBI chr  X:150,775,034...150,807,161
Ensembl chr  X:150,775,080...150,807,142 		JBrowse link
G Ntan1 N-terminal asparagine amidase decreases expression ISO Isotretinoin results in decreased expression of NTAN1 mRNA CTD PMID:20436886 NCBI chr10:2,111,085...2,126,123 JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 increases expression ISO Isotretinoin results in increased expression of NTRK2 mRNA CTD PMID:20436886 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Nudt21 nudix hydrolase 21 decreases expression ISO Isotretinoin results in decreased expression of NUDT21 mRNA CTD PMID:20436886 NCBI chr19:10,974,800...10,993,841
Ensembl chr19:10,974,241...10,991,682 		JBrowse link
G Nudt4 nudix hydrolase 4 decreases expression ISO Isotretinoin results in decreased expression of NUDT4 mRNA CTD PMID:20436886 NCBI chr 7:30,188,100...30,204,620
Ensembl chr 7:30,188,100...30,204,615 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A decreases expression ISO Isotretinoin results in decreased expression of OAS1 mRNA CTD PMID:20436886 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions
decreases expression		 ISO Isotretinoin inhibits the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]
Isotretinoin results in decreased expression of ODC1 mRNA		 CTD PMID:15225900 PMID:15982314 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Odr4 odr-4 GPCR localization factor homolog decreases expression ISO Isotretinoin results in decreased expression of ODR4 mRNA CTD PMID:20436886 NCBI chr13:62,369,109...62,424,287
Ensembl chr13:62,394,608...62,424,209 		JBrowse link
G Olah oleoyl-ACP hydrolase decreases expression ISO Isotretinoin results in decreased expression of OLAH mRNA CTD PMID:20436886 NCBI chr17:74,877,651...74,902,517
Ensembl chr17:74,877,655...74,902,518 		JBrowse link
G Olig3 oligodendrocyte transcription factor 3 increases expression ISO Isotretinoin results in increased expression of OLIG3 mRNA CTD PMID:31711903 NCBI chr 1:14,081,259...14,083,336
Ensembl chr 1:14,081,328...14,082,149 		JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 decreases expression ISO Isotretinoin results in decreased expression of ORMDL2 mRNA CTD PMID:20436886 NCBI chr 7:1,247,869...1,250,999
Ensembl chr 7:1,246,479...1,250,907 		JBrowse link
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 decreases expression ISO Isotretinoin results in decreased expression of OTUB2 mRNA CTD PMID:20436886 NCBI chr 6:122,545,029...122,563,651
Ensembl chr 6:122,545,061...122,563,644 		JBrowse link
G Pafah2 platelet-activating factor acetylhydrolase 2 decreases expression ISO Isotretinoin results in decreased expression of PAFAH2 mRNA CTD PMID:20436886 NCBI chr 5:146,607,050...146,636,203
Ensembl chr 5:146,613,498...146,634,943 		JBrowse link
G Pank3 pantothenate kinase 3 decreases expression ISO Isotretinoin results in decreased expression of PANK3 mRNA CTD PMID:20436886 NCBI chr10:20,229,129...20,252,955
Ensembl chr10:20,229,129...20,252,955 		JBrowse link
G Paqr3 progestin and adipoQ receptor family member 3 decreases expression ISO Isotretinoin results in decreased expression of PAQR3 mRNA CTD PMID:20436886 NCBI chr14:12,462,568...12,484,999
Ensembl chr14:12,462,563...12,479,994 		JBrowse link
G Pawr pro-apoptotic WT1 regulator decreases expression ISO Isotretinoin results in decreased expression of PAWR mRNA CTD PMID:20436886 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
G Pax6 paired box 6 increases expression ISO Isotretinoin results in increased expression of PAX6 mRNA CTD PMID:31711903 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Pccb propionyl-CoA carboxylase subunit beta decreases expression ISO Isotretinoin results in decreased expression of PCCB mRNA CTD PMID:20436886 NCBI chr 8:101,591,218...101,641,213
Ensembl chr 8:101,590,737...101,641,234 		JBrowse link
G Pcdh1 protocadherin 1 multiple interactions ISO [vorinostat co-treated with Isotretinoin] results in increased expression of PCDH1 mRNA CTD PMID:18769122 NCBI chr18:30,011,692...30,039,679
Ensembl chr18:30,013,185...30,039,318 		JBrowse link
G Pcolce procollagen C-endopeptidase enhancer increases expression ISO Isotretinoin results in increased expression of PCOLCE mRNA CTD PMID:20436886 NCBI chr12:19,084,191...19,090,508
Ensembl chr12:19,084,210...19,090,508 		JBrowse link
G Pctp phosphatidylcholine transfer protein decreases expression ISO Isotretinoin results in decreased expression of PCTP mRNA CTD PMID:20436886 NCBI chr10:74,808,887...74,856,260
Ensembl chr10:74,808,887...74,849,867 		JBrowse link
G Pde6a phosphodiesterase 6A decreases expression ISO Isotretinoin results in decreased expression of PDE6A mRNA CTD PMID:20436886 NCBI chr18:54,676,863...54,749,644
Ensembl chr18:54,676,863...54,748,816 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta increases expression ISO Isotretinoin results in increased expression of PDGFRB mRNA CTD PMID:20436886 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 decreases expression ISO Isotretinoin results in decreased expression of PDHA1 mRNA CTD PMID:20436886 NCBI chr  X:34,700,481...34,714,309
Ensembl chr  X:34,700,409...34,714,311 		JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta decreases expression ISO Isotretinoin results in decreased expression of PDHB mRNA CTD PMID:20436886 NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500 		JBrowse link
G Pdhx pyruvate dehydrogenase complex, component X decreases expression ISO Isotretinoin results in decreased expression of PDHX mRNA CTD PMID:20436886 NCBI chr 3:89,372,472...89,396,759
Ensembl chr 3:89,371,497...89,431,773 		JBrowse link
G Pdzk1 PDZ domain containing 1 decreases expression ISO Isotretinoin results in decreased expression of PDZK1 mRNA CTD PMID:20436886 NCBI chr 2:184,376,161...184,407,514
Ensembl chr 2:184,376,161...184,407,514 		JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase decreases expression ISO Isotretinoin results in decreased expression of PECR mRNA CTD PMID:20436886 NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511 		JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha decreases expression ISO Isotretinoin results in decreased expression of PEX11A mRNA CTD PMID:20436886 NCBI chr 1:133,680,091...133,687,172
Ensembl chr 1:133,680,091...133,687,172 		JBrowse link
G Pex13 peroxisomal biogenesis factor 13 decreases expression ISO Isotretinoin results in decreased expression of PEX13 mRNA CTD PMID:20436886 NCBI chr14:97,602,829...97,621,233
Ensembl chr14:97,603,539...97,621,262 		JBrowse link
G Pex16 peroxisomal biogenesis factor 16 decreases expression ISO Isotretinoin results in decreased expression of PEX16 mRNA CTD PMID:20436886 NCBI chr 3:78,347,212...78,352,603
Ensembl chr 3:78,343,164...78,353,207 		JBrowse link
G Pex19 peroxisomal biogenesis factor 19 decreases expression ISO Isotretinoin results in decreased expression of PEX19 mRNA CTD PMID:20436886 NCBI chr13:84,592,277...84,608,793
Ensembl chr13:84,592,312...84,608,608 		JBrowse link
G Pex3 peroxisomal biogenesis factor 3 decreases expression ISO Isotretinoin results in decreased expression of PEX3 mRNA CTD PMID:20436886 NCBI chr 1:7,912,508...7,954,474
Ensembl chr 1:7,912,506...7,954,518 		JBrowse link
G Pex7 peroxisomal biogenesis factor 7 decreases expression ISO Isotretinoin results in decreased expression of PEX7 mRNA CTD PMID:20436886 NCBI chr 1:14,582,698...14,646,686
Ensembl chr 1:14,582,699...14,646,748 		JBrowse link
G Pgd phosphogluconate dehydrogenase decreases expression ISO Isotretinoin results in decreased expression of PGD mRNA CTD PMID:20436886 NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Pgm1 phosphoglucomutase 1 decreases expression ISO Isotretinoin results in decreased expression of PGM1 mRNA CTD PMID:20436886 NCBI chr 5:114,595,298...114,654,728
Ensembl chr 5:114,595,293...114,654,728 		JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 decreases expression ISO Isotretinoin results in decreased expression of PGRMC1 mRNA CTD PMID:20436886 NCBI chr  X:115,832,865...115,841,060
Ensembl chr  X:115,832,884...115,888,682 		JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases expression ISO Isotretinoin results in increased expression of PHGDH mRNA CTD PMID:20436886 NCBI chr 2:185,906,964...185,936,160
Ensembl chr 2:185,906,966...185,935,944 		JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 multiple interactions ISO [vorinostat co-treated with Isotretinoin] results in increased expression of PHLDA1 mRNA CTD PMID:18769122 NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861 		JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 decreases expression ISO Isotretinoin results in decreased expression of PHLDA2 mRNA CTD PMID:20436886 NCBI chr 1:198,696,897...198,699,292
Ensembl chr 1:198,696,897...198,697,836 		JBrowse link
G Pik3c2g phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma decreases expression ISO Isotretinoin results in decreased expression of PIK3C2G mRNA CTD PMID:20436886 NCBI chr 4:172,483,752...172,851,623
Ensembl chr 4:172,484,345...172,850,544 		JBrowse link
G Pir pirin decreases expression
increases expression		 ISO Isotretinoin results in decreased expression of PIR mRNA
Isotretinoin results in increased expression of PIR mRNA		 CTD PMID:15982314 PMID:20436886 NCBI chr  X:30,108,536...30,219,269
Ensembl chr  X:30,108,538...30,219,218 		JBrowse link
G Pklr pyruvate kinase L/R decreases expression ISO Isotretinoin results in decreased expression of PKLR mRNA CTD PMID:20436886 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870 		JBrowse link
G Pkp1 plakophilin 1 increases expression ISO Isotretinoin results in increased expression of PKP1 mRNA CTD PMID:20436886 NCBI chr13:47,309,603...47,357,551
Ensembl chr13:47,309,614...47,357,465 		JBrowse link
G Pla2g7 phospholipase A2 group VII decreases expression ISO Isotretinoin results in decreased expression of PLA2G7 mRNA CTD PMID:20436886 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476 		JBrowse link
G Plat plasminogen activator, tissue type increases expression ISO Isotretinoin results in increased expression of PLAT mRNA CTD PMID:15982314 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Plcl2 phospholipase C-like 2 increases expression ISO Isotretinoin results in increased expression of PLCL2 mRNA CTD PMID:20436886 NCBI chr 9:3,292,564...3,477,009
Ensembl chr 9:3,292,695...3,477,009 		JBrowse link
G Plin2 perilipin 2 decreases expression ISO Isotretinoin results in decreased expression of PLIN2 mRNA CTD PMID:20436886 NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319 		JBrowse link
G Plpp3 phospholipid phosphatase 3 increases expression ISO Isotretinoin results in increased expression of PLPP3 mRNA CTD PMID:20436886 NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205 		JBrowse link
G Pltp phospholipid transfer protein increases expression ISO Isotretinoin results in increased expression of PLTP mRNA CTD PMID:20436886 NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647 		JBrowse link
G Pmel premelanosome protein decreases expression ISO Isotretinoin results in decreased expression of PMEL mRNA CTD PMID:20436886 NCBI chr 7:1,138,202...1,148,735
Ensembl chr 7:1,138,586...1,148,746 		JBrowse link
G Pmpcb peptidase, mitochondrial processing subunit beta decreases expression ISO Isotretinoin results in decreased expression of PMPCB mRNA CTD PMID:20436886 NCBI chr 4:13,297,583...13,310,363
Ensembl chr 4:13,297,559...13,310,367 		JBrowse link
G Pmvk phosphomevalonate kinase decreases expression ISO Isotretinoin results in decreased expression of PMVK mRNA CTD PMID:20436886 NCBI chr 2:174,876,586...174,886,365
Ensembl chr 2:174,876,657...174,886,364 		JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 decreases expression ISO Isotretinoin results in decreased expression of PNPLA3 mRNA CTD PMID:20436886 NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077 		JBrowse link
G Polr2m RNA polymerase II subunit M increases expression ISO Isotretinoin results in increased expression of POLR2M mRNA CTD PMID:20436886 NCBI chr 8:72,131,992...72,139,423
Ensembl chr 8:72,131,530...72,243,036 		JBrowse link
G Pon3 paraoxonase 3 decreases expression ISO Isotretinoin results in decreased expression of PON3 mRNA CTD PMID:20436886 NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855 		JBrowse link
G Popdc2 popeye domain containing 2 decreases expression ISO Isotretinoin results in decreased expression of POPDC2 mRNA CTD PMID:20436886 NCBI chr11:62,351,843...62,398,688
Ensembl chr11:62,374,759...62,390,756 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression EXP Isotretinoin results in increased expression of PPARG mRNA CTD PMID:19041696 PMID:19212007 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppif peptidylprolyl isomerase F decreases expression ISO Isotretinoin results in decreased expression of PPIF mRNA CTD PMID:20436886 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913 		JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B decreases expression ISO Isotretinoin results in decreased expression of PPM1B mRNA CTD PMID:20436886 NCBI chr 6:9,646,695...9,707,471
Ensembl chr 6:9,655,765...9,707,974 		JBrowse link
G Ppp1r16b protein phosphatase 1, regulatory subunit 16B increases expression ISO Isotretinoin results in increased expression of PPP1R16B mRNA CTD PMID:20436886 NCBI chr 3:147,323,652...147,419,658
Ensembl chr 3:147,324,126...147,418,937 		JBrowse link
G Prdx2 peroxiredoxin 2 decreases expression ISO Isotretinoin results in decreased expression of PRDX2 mRNA CTD PMID:20436886 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Prepl prolyl endopeptidase-like decreases expression ISO Isotretinoin results in decreased expression of PREPL mRNA CTD PMID:20436886 NCBI chr 6:9,580,367...9,609,957
Ensembl chr 6:9,580,217...9,607,772 		JBrowse link
G Pros1 protein S increases expression ISO Isotretinoin results in increased expression of PROS1 mRNA CTD PMID:20436886 NCBI chr11:230,597...311,288
Ensembl chr11:230,696...311,286 		JBrowse link
G Prss8 serine protease 8 decreases expression ISO Isotretinoin results in decreased expression of PRSS8 mRNA CTD PMID:20436886 NCBI chr 1:182,536,229...182,540,745
Ensembl chr 1:182,536,229...182,540,815 		JBrowse link
G Psma1 proteasome 20S subunit alpha 1 decreases expression ISO Isotretinoin results in decreased expression of PSMA1 mRNA CTD PMID:20436886 NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472 		JBrowse link
G Psma3 proteasome 20S subunit alpha 3 decreases expression ISO Isotretinoin results in decreased expression of PSMA3 mRNA CTD PMID:20436886 NCBI chr 6:89,483,741...89,503,775
Ensembl chr 6:89,483,727...89,504,965 		JBrowse link
G Psma4 proteasome 20S subunit alpha 4 decreases expression ISO Isotretinoin results in decreased expression of PSMA4 mRNA CTD PMID:20436886 NCBI chr 8:55,340,431...55,347,893
Ensembl chr 8:55,340,386...55,347,890 		JBrowse link
G Psma5 proteasome 20S subunit alpha 5 decreases expression ISO Isotretinoin results in decreased expression of PSMA5 mRNA CTD PMID:20436886 NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731 		JBrowse link
G Psma7 proteasome 20S subunit alpha 7 decreases expression ISO Isotretinoin results in decreased expression of PSMA7 mRNA CTD PMID:20436886 NCBI chr 3:167,137,279...167,143,626
Ensembl chr 3:167,137,263...167,143,672 		JBrowse link
G Psmb5 proteasome 20S subunit beta 5 decreases expression ISO Isotretinoin results in decreased expression of PSMB5 mRNA CTD PMID:20436886 NCBI chr15:28,072,772...28,077,367
Ensembl chr15:28,072,781...28,077,440 		JBrowse link
G Ptgds prostaglandin D2 synthase increases expression ISO Isotretinoin results in increased expression of PTGDS mRNA CTD PMID:20436886 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO Isotretinoin results in decreased expression of PTGS1 mRNA CTD PMID:15982314 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Isotretinoin results in decreased expression of PTGS2 mRNA CTD PMID:15982314 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptprb protein tyrosine phosphatase, receptor type, B increases expression ISO Isotretinoin results in increased expression of PTPRB mRNA CTD PMID:20436886 NCBI chr 7:51,953,375...52,034,751
Ensembl chr 7:51,930,015...52,034,748 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C increases expression ISO Isotretinoin results in increased expression of PTPRC mRNA CTD PMID:20436886 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Ptprg protein tyrosine phosphatase, receptor type, G increases expression ISO Isotretinoin results in increased expression of PTPRG mRNA CTD PMID:20436886 NCBI chr15:12,872,284...13,552,186
Ensembl chr15:12,871,721...13,554,094 		JBrowse link
G Ptprm protein tyrosine phosphatase, receptor type, M increases expression ISO Isotretinoin results in increased expression of PTPRM mRNA CTD PMID:20436886 NCBI chr 9:106,639,573...107,343,698
Ensembl chr 9:106,639,573...107,343,698 		JBrowse link
G Ptrh2 peptidyl-tRNA hydrolase 2 decreases expression ISO Isotretinoin results in decreased expression of PTRH2 mRNA CTD PMID:20436886 NCBI chr10:71,505,113...71,515,297
Ensembl chr10:71,504,956...71,515,398 		JBrowse link
G Pts 6-pyruvoyl-tetrahydropterin synthase decreases expression ISO Isotretinoin results in decreased expression of PTS mRNA CTD PMID:20436886 NCBI chr 8:50,870,838...50,877,878
Ensembl chr 8:50,870,841...50,877,869 		JBrowse link
G Pxmp2 peroxisomal membrane protein 2 decreases expression ISO Isotretinoin results in decreased expression of PXMP2 mRNA CTD PMID:20436886 NCBI chr12:46,394,051...46,404,561
Ensembl chr12:46,394,193...46,404,557 		JBrowse link
G Pxmp4 peroxisomal membrane protein 4 decreases expression ISO Isotretinoin results in decreased expression of PXMP4 mRNA CTD PMID:20436886 NCBI chr 3:143,093,371...143,110,620
Ensembl chr 3:143,093,018...143,110,651 		JBrowse link
G Qki QKI, KH domain containing RNA binding increases expression ISO Isotretinoin results in increased expression of QKI mRNA CTD PMID:20436886 NCBI chr 1:50,387,698...50,501,568
Ensembl chr 1:50,387,698...50,498,831 		JBrowse link
G Rab27a RAB27A, member RAS oncogene family decreases expression ISO Isotretinoin results in decreased expression of RAB27A mRNA CTD PMID:20436886 NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829 		JBrowse link
G Rab38 RAB38, member RAS oncogene family decreases expression ISO Isotretinoin results in decreased expression of RAB38 mRNA CTD PMID:20436886 NCBI chr 1:142,182,566...142,262,923
Ensembl chr 1:142,182,556...142,262,924 		JBrowse link
G Rab5if RAB5 interacting factor decreases expression ISO Isotretinoin results in decreased expression of RAB5IF mRNA CTD PMID:20436886 NCBI chr 3:145,357,990...145,368,012
Ensembl chr 3:145,357,861...145,368,012 		JBrowse link
G Rac2 Rac family small GTPase 2 increases expression ISO Isotretinoin results in increased expression of RAC2 mRNA CTD PMID:20436886 NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720 		JBrowse link
G Rara retinoic acid receptor, alpha increases expression
decreases expression		 ISO
EXP		 Isotretinoin results in increased expression of RARA mRNA
Isotretinoin results in decreased expression of RARA mRNA		 CTD PMID:9262057 PMID:19041696 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Rarb retinoic acid receptor, beta multiple interactions
increases expression
decreases expression		 ISO
EXP		 [LAQ824 co-treated with Isotretinoin] results in increased acetylation of RARB promoter; [LAQ824 co-treated with Isotretinoin] results in increased expression of RARB mRNA; R116010 promotes the reaction [Isotretinoin results in increased expression of RARB mRNA]
Isotretinoin results in decreased expression of RARB mRNA		 CTD PMID:17237267 PMID:17486130 PMID:19041696 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
G Rarg retinoic acid receptor, gamma decreases expression EXP Isotretinoin results in decreased expression of RARG mRNA CTD PMID:19041696 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177 		JBrowse link
G Rarres1 retinoic acid receptor responder 1 multiple interactions
increases expression		 ISO AGN 193109 inhibits the reaction [Isotretinoin results in increased expression of RARRES1 mRNA] CTD PMID:16575387 NCBI chr 2:151,749,715...151,783,975
Ensembl chr 2:151,749,715...151,783,978 		JBrowse link
G Rasal1 RAS protein activator like 1 decreases expression ISO Isotretinoin results in decreased expression of RASAL1 mRNA CTD PMID:20436886 NCBI chr12:35,881,269...35,913,727
Ensembl chr12:35,881,270...35,913,727 		JBrowse link
G Rassf2 Ras association domain family member 2 increases expression ISO Isotretinoin results in increased expression of RASSF2 mRNA CTD PMID:20436886 NCBI chr 3:119,244,288...119,280,462
Ensembl chr 3:119,245,821...119,280,431 		JBrowse link
G Rbks ribokinase decreases expression ISO Isotretinoin results in decreased expression of RBKS mRNA CTD PMID:20436886 NCBI chr 6:24,747,651...24,824,290
Ensembl chr 6:24,747,293...24,824,290 		JBrowse link
G Rbm47 RNA binding motif protein 47 decreases expression ISO Isotretinoin results in decreased expression of RBM47 mRNA CTD PMID:20436886 NCBI chr14:42,053,290...42,191,572
Ensembl chr14:42,154,142...42,189,431 		JBrowse link
G Rbpms RNA binding protein, mRNA processing factor increases expression ISO Isotretinoin results in increased expression of RBPMS mRNA CTD PMID:20436886 NCBI chr16:58,239,370...58,395,424
Ensembl chr16:58,239,474...58,395,426 		JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 decreases expression ISO Isotretinoin results in decreased expression of RC3H2 mRNA CTD PMID:20436886 NCBI chr 3:21,121,531...21,186,711
Ensembl chr 3:21,110,679...21,179,933 		JBrowse link
G Rdh11 retinol dehydrogenase 11 decreases expression ISO Isotretinoin results in decreased expression of RDH11 mRNA CTD PMID:20436886 NCBI chr 6:97,979,377...97,995,252
Ensembl chr 6:97,979,378...97,995,252 		JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions ISO Isotretinoin affects the localization of and results in decreased activity of REL protein CTD PMID:18652567 PMID:19066126 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Isotretinoin affects the localization of and results in decreased activity of RELA protein CTD PMID:18652567 PMID:19066126 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Retreg1 reticulophagy regulator 1 decreases expression ISO Isotretinoin results in decreased expression of RETREG1 mRNA CTD PMID:20436886 NCBI chr 2:76,335,609...76,474,817
Ensembl chr 2:76,335,609...76,493,898 		JBrowse link
G Rfk riboflavin kinase decreases expression ISO Isotretinoin results in decreased expression of RFK mRNA CTD PMID:20436886 NCBI chr 1:214,799,880...214,807,440
Ensembl chr 1:214,799,825...214,807,438 		JBrowse link
G RGD1309104 similar to RIKEN cDNA 1700025G04 gene increases expression ISO Isotretinoin results in increased expression of C1ORF21 mRNA CTD PMID:20436886 NCBI chr13:63,982,587...64,199,676
Ensembl chr13:63,990,592...64,199,596 		JBrowse link
G RGD1559459 similar to Expressed sequence AI788959 decreases expression ISO Isotretinoin results in decreased expression of UGT2B28 mRNA CTD PMID:20436886 NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704 		JBrowse link
G Rhoa ras homolog family member A decreases expression ISO Isotretinoin results in decreased expression of RHOA mRNA CTD PMID:15982314 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Rhob ras homolog family member B decreases expression ISO Isotretinoin results in decreased expression of RHOB mRNA CTD PMID:15982314 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108 		JBrowse link
G Rhobtb3 Rho-related BTB domain containing 3 increases expression ISO Isotretinoin results in increased expression of RHOBTB3 mRNA CTD PMID:20436886 NCBI chr 2:5,363,388...5,419,164
Ensembl chr 2:5,363,388...5,419,041 		JBrowse link
G Rida reactive intermediate imine deaminase A homolog decreases expression ISO Isotretinoin results in decreased expression of UK114 mRNA CTD PMID:20436886 NCBI chr 7:65,691,429...65,705,257
Ensembl chr 7:65,691,435...65,705,716 		JBrowse link
G Riox2 ribosomal oxygenase 2 decreases expression ISO Isotretinoin results in decreased expression of RIOX2 mRNA CTD PMID:20436886 NCBI chr11:40,861,365...40,884,782
Ensembl chr11:40,860,774...40,884,574 		JBrowse link
G Rmdn1 regulator of microtubule dynamics 1 decreases expression ISO Isotretinoin results in decreased expression of RMDN1 mRNA CTD PMID:20436886 NCBI chr 5:33,070,267...33,093,922
Ensembl chr 5:33,070,265...33,127,328 		JBrowse link
G Rnaset2 ribonuclease T2 increases expression ISO Isotretinoin results in increased expression of RNASET2 mRNA CTD PMID:20436886 NCBI chr 1:52,576,344...52,603,151
Ensembl chr 1:52,585,929...52,603,147 		JBrowse link
G Rnd3 Rho family GTPase 3 decreases expression ISO Isotretinoin results in decreased expression of RND3 mRNA CTD PMID:20436886 NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327 		JBrowse link
G Rnf128 ring finger protein 128 decreases expression ISO Isotretinoin results in decreased expression of RNF128 mRNA CTD PMID:20436886 NCBI chr  X:103,183,643...103,298,431
Ensembl chr  X:103,183,831...103,298,423 		JBrowse link
G Rnf38 ring finger protein 38 increases expression ISO Isotretinoin results in increased expression of RNF38 mRNA CTD PMID:20436886 NCBI chr 5:58,358,771...58,467,424
Ensembl chr 5:58,361,976...58,467,446 		JBrowse link
G Rnf5 ring finger protein 5 decreases expression ISO Isotretinoin results in decreased expression of RNF5 mRNA CTD PMID:15982314 NCBI chr20:4,145,539...4,147,985
Ensembl chr20:4,145,507...4,147,985 		JBrowse link
G Ro60 Ro60, Y RNA binding protein decreases expression ISO Isotretinoin results in decreased expression of RO60 mRNA CTD PMID:20436886 NCBI chr13:55,499,514...55,520,504
Ensembl chr13:55,499,534...55,520,504 		JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 increases expression ISO Isotretinoin results in increased expression of ROR1 mRNA CTD PMID:20436886 NCBI chr 5:114,744,311...115,088,155
Ensembl chr 5:114,744,304...115,088,155 		JBrowse link
G Rora RAR-related orphan receptor A decreases expression ISO Isotretinoin results in decreased expression of RORA mRNA CTD PMID:20436886 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931 		JBrowse link
G Rpe65 retinoid isomerohydrolase RPE65 multiple interactions ISO
EXP		 [Isotretinoin binds to and results in decreased activity of RPE65 protein] which results in decreased abundance of Retinaldehyde CTD PMID:16411761 NCBI chr 2:248,766,497...248,798,403
Ensembl chr 2:248,766,612...248,798,403 		JBrowse link
G Rpp40 ribonuclease P/MRP subunit p40 decreases expression ISO Isotretinoin results in decreased expression of RPP40 mRNA CTD PMID:20436886 NCBI chr17:28,947,730...28,956,790
Ensembl chr17:28,947,734...28,956,788 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 increases expression ISO Isotretinoin results in increased expression of HLA-E mRNA CTD PMID:20436886 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-Bb RT1 class II, locus Bb increases expression ISO Isotretinoin results in increased expression of HLA-DQB1 mRNA CTD PMID:20436886 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 increases expression ISO Isotretinoin results in increased expression of HLA-F mRNA CTD PMID:20436886 NCBI chr20:3,403,418...3,479,476 JBrowse link
G RT1-Ha RT1 class II, locus Ha increases expression ISO Isotretinoin results in increased expression of HLA-DPA1 mRNA CTD PMID:20436886 NCBI chr20:4,760,631...4,770,662
Ensembl chr20:4,760,118...4,770,244 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 increases expression ISO Isotretinoin results in increased expression of HLA-G mRNA CTD PMID:20436886 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
G Rtca RNA 3'-terminal phosphate cyclase decreases expression ISO Isotretinoin results in decreased expression of RTCA mRNA CTD PMID:20436886 NCBI chr 2:204,455,175...204,476,450
Ensembl chr 2:204,455,175...204,476,460 		JBrowse link
G Rtn1 reticulon 1 increases expression ISO Isotretinoin results in increased expression of RTN1 mRNA CTD PMID:20436886 NCBI chr 6:90,763,212...90,983,436
Ensembl chr 6:90,763,216...90,983,436 		JBrowse link
G Rxra retinoid X receptor alpha multiple interactions
increases activity
affects binding		 ISO
EXP		 Isotretinoin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]
Isotretinoin results in increased activity of RXRA protein
Isotretinoin binds to RXRA protein		 CTD PMID:16632523 PMID:21543282 PMID:31566444 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Rxrb retinoid X receptor beta decreases expression EXP Isotretinoin results in decreased expression of RXRB mRNA CTD PMID:19041696 NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773 		JBrowse link
G S100a1 S100 calcium binding protein A1 decreases expression ISO Isotretinoin results in decreased expression of S100A1 mRNA CTD PMID:15982314 NCBI chr 2:175,993,922...175,998,765
Ensembl chr 2:175,993,922...175,999,544 		JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression ISO Isotretinoin results in increased expression of S100A4 mRNA CTD PMID:20436886 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254 		JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO Isotretinoin results in increased expression of S100A8 mRNA CTD PMID:15982314 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO Isotretinoin results in increased expression of S100A9 mRNA CTD PMID:15982314 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Samm50 SAMM50 sorting and assembly machinery component decreases expression ISO Isotretinoin results in decreased expression of SAMM50 mRNA CTD PMID:20436886 NCBI chr 7:115,317,472...115,341,682
Ensembl chr 7:115,317,404...115,341,682 		JBrowse link
G Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 increases expression ISO Isotretinoin results in increased expression of SAMSN1 mRNA CTD PMID:20436886 NCBI chr11:14,484,523...14,534,900
Ensembl chr11:14,483,893...14,534,900 		JBrowse link
G Sar1b secretion associated, Ras related GTPase 1B decreases expression ISO Isotretinoin results in decreased expression of SAR1B mRNA CTD PMID:20436886 NCBI chr10:36,024,443...36,054,067
Ensembl chr10:36,024,382...36,054,066 		JBrowse link
G Sc5d sterol-C5-desaturase decreases expression ISO Isotretinoin results in decreased expression of SC5D mRNA CTD PMID:20436886 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273 		JBrowse link
G Scamp1 secretory carrier membrane protein 1 decreases expression ISO Isotretinoin results in decreased expression of SCAMP1 mRNA CTD PMID:20436886 NCBI chr 2:25,433,958...25,516,734
Ensembl chr 2:25,433,959...25,516,673 		JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha increases expression ISO Isotretinoin results in increased expression of SCNN1A mRNA CTD PMID:18769122 NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181 		JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 decreases expression ISO Isotretinoin results in decreased expression of SDF2L1 mRNA CTD PMID:20436886 NCBI chr11:83,872,659...83,874,902
Ensembl chr11:83,872,659...83,874,902 		JBrowse link
G Sdhc succinate dehydrogenase complex subunit C decreases expression ISO Isotretinoin results in decreased expression of SDHC mRNA CTD PMID:20436886 NCBI chr13:83,544,652...83,565,560
Ensembl chr13:83,544,652...83,566,253 		JBrowse link
G Selplg selectin P ligand increases expression ISO Isotretinoin results in increased expression of SELPLG mRNA CTD PMID:20436886 NCBI chr12:42,796,690...42,809,908
Ensembl chr12:42,796,580...42,812,585 		JBrowse link
G Septin11 septin 11 decreases expression ISO Isotretinoin results in decreased expression of SEPTIN11 mRNA CTD PMID:20436886 NCBI chr14:14,844,759...14,990,856
Ensembl chr14:14,844,580...14,990,853 		JBrowse link
G Serhl2 serine hydrolase-like 2 increases expression ISO Isotretinoin results in increased expression of SERHL2 mRNA CTD PMID:20436886 NCBI chr 7:114,246,056...114,272,781
Ensembl chr 7:114,246,056...114,272,781 		JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N increases expression ISO Isotretinoin results in increased expression of SERPINA3 mRNA CTD PMID:15982314 NCBI chr 6:123,323,632...123,331,166
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Serpinb2 serpin family B member 2 decreases expression ISO Isotretinoin results in decreased expression of SERPINB2 mRNA CTD PMID:15982314 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408 		JBrowse link
G Serpinb8 serpin family B member 8 decreases expression ISO Isotretinoin results in decreased expression of SERPINB8 mRNA CTD PMID:15982314 NCBI chr13:23,626,945...23,650,270
Ensembl chr13:23,626,945...23,650,835 		JBrowse link
G Serpinb9 serpin family B member 9 decreases expression ISO Isotretinoin results in decreased expression of SERPINB9 mRNA CTD PMID:15982314 NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230 		JBrowse link
G Serpine1 serpin family E member 1 decreases expression EXP Isotretinoin results in decreased expression of SERPINE1 mRNA CTD PMID:15972972 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Serping1 serpin family G member 1 increases expression ISO Isotretinoin results in increased expression of SERPING1 mRNA CTD PMID:20436886 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034 		JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 decreases expression ISO Isotretinoin results in decreased expression of SGK2 mRNA CTD PMID:20436886 NCBI chr 3:151,644,102...151,669,480
Ensembl chr 3:151,644,102...151,669,480 		JBrowse link
G Shh sonic hedgehog signaling molecule increases expression ISO Isotretinoin results in increased expression of SHH mRNA CTD PMID:26096596 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 decreases expression ISO Isotretinoin results in decreased expression of SHMT1 mRNA CTD PMID:20436886 NCBI chr10:45,468,698...45,497,820
Ensembl chr10:45,468,700...45,497,820 		JBrowse link
G Sirpa signal-regulatory protein alpha increases expression ISO Isotretinoin results in increased expression of SIRPA mRNA CTD PMID:20436886 NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098 		JBrowse link
G Skic8 SKI8 subunit of superkiller complex decreases expression ISO Isotretinoin results in decreased expression of SKIC8 mRNA CTD PMID:20436886 NCBI chr 8:55,103,542...55,120,837
Ensembl chr 8:55,103,545...55,120,813 		JBrowse link
G Sla src-like adaptor increases expression ISO Isotretinoin results in increased expression of SLA mRNA CTD PMID:20436886 NCBI chr 7:98,534,431...98,584,810
Ensembl chr 7:98,535,368...98,584,648 		JBrowse link
G Slc11a2 solute carrier family 11 member 2 decreases expression ISO Isotretinoin results in decreased expression of SLC11A2 mRNA CTD PMID:20436886 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145 		JBrowse link
G Slc15a1 solute carrier family 15 member 1 decreases expression ISO Isotretinoin results in decreased expression of SLC15A1 mRNA CTD PMID:20436886 NCBI chr15:98,537,641...98,582,544
Ensembl chr15:98,537,641...98,582,545 		JBrowse link
G Slc16a1 solute carrier family 16 member 1 decreases expression ISO Isotretinoin results in decreased expression of SLC16A1 mRNA CTD PMID:15982314 NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611 		JBrowse link
G Slc16a7 solute carrier family 16 member 7 decreases expression ISO Isotretinoin results in decreased expression of SLC16A7 mRNA CTD PMID:20436886 NCBI chr 7:61,043,667...61,211,547
Ensembl chr 7:61,051,167...61,154,994 		JBrowse link
G Slc22a18 solute carrier family 22, member 18 decreases expression ISO Isotretinoin results in decreased expression of SLC22A18 mRNA CTD PMID:20436886 NCBI chr 1:198,670,626...198,694,977
Ensembl chr 1:198,671,731...198,694,975 		JBrowse link
G Slc25a11 solute carrier family 25 member 11 decreases expression ISO Isotretinoin results in decreased expression of SLC25A11 mRNA CTD PMID:20436886 NCBI chr10:55,358,163...55,360,278
Ensembl chr10:55,357,597...55,360,410 		JBrowse link
G Slc25a15 solute carrier family 25 member 15 decreases expression ISO Isotretinoin results in decreased expression of SLC25A15 mRNA CTD PMID:20436886 NCBI chr16:69,631,581...69,654,869
Ensembl chr16:69,634,414...69,653,010 		JBrowse link
G Slc25a16 solute carrier family 25 member 16 decreases expression ISO Isotretinoin results in decreased expression of SLC25A16 mRNA CTD PMID:20436886 NCBI chr20:25,661,158...25,717,558
Ensembl chr20:25,662,055...25,716,319 		JBrowse link
G Slc25a17 solute carrier family 25 member 17 decreases expression ISO Isotretinoin results in decreased expression of SLC25A17 mRNA CTD PMID:20436886 NCBI chr 7:112,844,375...112,887,014
Ensembl chr 7:112,844,375...112,925,945 		JBrowse link
G Slc26a3 solute carrier family 26 member 3 decreases expression ISO Isotretinoin results in decreased expression of SLC26A3 mRNA CTD PMID:20436886 NCBI chr 6:48,023,892...48,064,829
Ensembl chr 6:48,023,892...48,064,772 		JBrowse link
G Slc27a2 solute carrier family 27 member 2 decreases expression ISO Isotretinoin results in decreased expression of SLC27A2 mRNA CTD PMID:20436886 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression EXP Isotretinoin results in increased expression of SLC2A4 mRNA CTD PMID:19212007 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
G Slc30a1 solute carrier family 30 member 1 decreases expression ISO Isotretinoin results in decreased expression of SLC30A1 mRNA CTD PMID:20436886 NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910 		JBrowse link
G Slc30a10 solute carrier family 30, member 10 decreases expression ISO Isotretinoin results in decreased expression of SLC30A10 mRNA CTD PMID:20436886 NCBI chr13:96,998,143...97,048,076
Ensembl chr13:96,998,143...97,009,103 		JBrowse link
G Slc31a1 solute carrier family 31 member 1 decreases expression ISO Isotretinoin results in decreased expression of SLC31A1 mRNA CTD PMID:20436886 NCBI chr 5:75,814,744...75,844,241
Ensembl chr 5:75,814,743...75,844,228 		JBrowse link
G Slc35a2 solute carrier family 35 member A2 decreases expression ISO Isotretinoin results in decreased expression of SLC35A2 mRNA CTD PMID:20436886 NCBI chr  X:14,608,145...14,616,937
Ensembl chr  X:14,608,055...14,616,678 		JBrowse link
G Slc35b1 solute carrier family 35, member B1 decreases expression ISO Isotretinoin results in decreased expression of SLC35B1 mRNA CTD PMID:20436886 NCBI chr10:80,327,921...80,335,279
Ensembl chr10:80,327,945...80,335,274 		JBrowse link
G Slc39a14 solute carrier family 39 member 14 increases expression ISO Isotretinoin results in increased expression of SLC39A14 mRNA CTD PMID:20436886 NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524 		JBrowse link
G Slc39a8 solute carrier family 39 member 8 decreases expression ISO Isotretinoin results in decreased expression of SLC39A8 mRNA CTD PMID:20436886 NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129 		JBrowse link
G Slc46a3 solute carrier family 46, member 3 decreases expression ISO Isotretinoin results in decreased expression of SLC46A3 mRNA CTD PMID:20436886 NCBI chr12:7,140,610...7,157,093
Ensembl chr12:7,140,668...7,157,092 		JBrowse link
G Slc50a1 solute carrier family 50 member 1 decreases expression ISO Isotretinoin results in decreased expression of SLC50A1 mRNA CTD PMID:20436886 NCBI chr 2:174,677,985...174,680,366
Ensembl chr 2:174,677,708...174,680,366 		JBrowse link
G Slc5a6 solute carrier family 5 member 6 decreases expression ISO Isotretinoin results in decreased expression of SLC5A6 mRNA CTD PMID:20436886 NCBI chr 6:25,319,187...25,331,713
Ensembl chr 6:25,320,442...25,331,712 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 decreases expression ISO Isotretinoin results in decreased expression of SLC7A5 mRNA CTD PMID:20436886 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
G Slco4c1 solute carrier organic anion transporter family, member 4C1 decreases expression ISO Isotretinoin results in decreased expression of SLCO4C1 mRNA CTD PMID:20436886 NCBI chr 9:97,180,162...97,229,135
Ensembl chr 9:97,178,861...97,229,715 		JBrowse link
G Slit3 slit guidance ligand 3 increases expression ISO Isotretinoin results in increased expression of SLIT3 mRNA CTD PMID:20436886 NCBI chr10:19,571,798...20,156,634
Ensembl chr10:19,571,684...20,156,634 		JBrowse link
G Smyd3 SET and MYND domain containing 3 increases expression ISO Isotretinoin results in increased expression of SMYD3 mRNA CTD PMID:20436886 NCBI chr13:90,709,263...91,266,209
Ensembl chr13:90,709,270...91,266,253 		JBrowse link
G Sned1 sushi, nidogen and EGF-like domains 1 increases expression ISO Isotretinoin results in increased expression of SNED1 mRNA CTD PMID:20436886 NCBI chr 9:93,774,087...93,834,003
Ensembl chr 9:93,774,119...93,830,694 		JBrowse link
G Snx13 sorting nexin 13 decreases expression ISO Isotretinoin results in decreased expression of SNX13 mRNA CTD PMID:20436886 NCBI chr 6:51,758,258...51,862,260
Ensembl chr 6:51,753,036...51,860,224 		JBrowse link
G Soat1 sterol O-acyltransferase 1 decreases expression ISO Isotretinoin results in decreased expression of SOAT1 mRNA CTD PMID:20436886 NCBI chr13:68,552,274...68,597,529
Ensembl chr13:68,552,317...68,597,494 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 decreases expression ISO Isotretinoin results in decreased expression of SOCS1 mRNA CTD PMID:15982314 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Socs2 suppressor of cytokine signaling 2 increases expression ISO Isotretinoin results in increased expression of SOCS2 mRNA CTD PMID:15982314 NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548 		JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO Isotretinoin results in decreased expression of SOD2 mRNA CTD PMID:20436886 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 decreases expression ISO Isotretinoin results in decreased expression of SORBS1 mRNA CTD PMID:20436886 NCBI chr 1:239,107,882...239,330,276
Ensembl chr 1:239,108,777...239,330,169 		JBrowse link
G Sord sorbitol dehydrogenase decreases expression ISO Isotretinoin results in decreased expression of SORD mRNA CTD PMID:20436886 NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133 		JBrowse link
G Sort1 sortilin 1 decreases expression ISO Isotretinoin results in decreased expression of SORT1 mRNA CTD PMID:20436886 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354 		JBrowse link
G Sox17 SRY-box transcription factor 17 decreases localization ISO Isotretinoin results in decreased localization of SOX17 protein CTD PMID:24154490 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Spcs3 signal peptidase complex subunit 3 decreases expression ISO Isotretinoin results in decreased expression of SPCS3 mRNA CTD PMID:20436886 NCBI chr16:37,305,358...37,310,792
Ensembl chr16:37,305,305...37,331,746 		JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO Isotretinoin results in increased expression of SPP1 mRNA CTD PMID:18769122 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 increases expression ISO Isotretinoin results in increased expression of SPRED2 mRNA CTD PMID:20436886 NCBI chr14:94,226,312...94,248,162
Ensembl chr14:94,148,837...94,249,162 		JBrowse link
G Sprr1b small proline-rich protein 1B increases expression ISO Isotretinoin results in increased expression of SPRR1B mRNA CTD PMID:15982314 NCBI chr 2:178,009,130...178,009,567
Ensembl chr 2:178,009,130...178,009,567 		JBrowse link
G Sprr3 small proline-rich protein 3 decreases expression ISO Isotretinoin results in decreased expression of SPRR3 mRNA CTD PMID:18769122 NCBI chr 2:178,027,743...178,028,501
Ensembl chr 2:178,027,425...178,029,891 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases expression ISO Isotretinoin results in decreased expression of SRD5A1 mRNA CTD PMID:20436886 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Srpx2 sushi-repeat-containing protein, X-linked 2 decreases expression ISO Isotretinoin results in decreased expression of SRPX2 mRNA CTD PMID:20436886 NCBI chr  X:97,106,455...97,132,197
Ensembl chr  X:97,106,561...97,132,195 		JBrowse link
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 decreases expression ISO Isotretinoin results in decreased expression of ST6GALNAC4 mRNA CTD PMID:20436886 NCBI chr 3:15,872,230...15,885,250
Ensembl chr 3:15,872,532...15,885,243 		JBrowse link
G Stambp Stam binding protein decreases expression ISO Isotretinoin results in decreased expression of STAMBP mRNA CTD PMID:20436886 NCBI chr 4:116,055,563...116,083,563
Ensembl chr 4:116,056,057...116,080,543 		JBrowse link
G Stap2 signal transducing adaptor family member 2 decreases expression ISO Isotretinoin results in decreased expression of STAP2 mRNA CTD PMID:20436886 NCBI chr 9:828,369...838,648
Ensembl chr 9:828,372...837,219 		JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression ISO Isotretinoin results in decreased expression of STIP1 mRNA CTD PMID:18769122 NCBI chr 1:204,209,434...204,228,452
Ensembl chr 1:204,178,932...204,228,476 		JBrowse link
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha decreases expression ISO Isotretinoin results in decreased expression of SUCLG1 mRNA CTD PMID:20436886 NCBI chr 4:105,308,236...105,337,595
Ensembl chr 4:105,308,039...105,337,600 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases expression ISO Isotretinoin results in increased expression of SULT2A1 mRNA CTD PMID:15982314 NCBI chr 1:75,451,178...75,508,142
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
G Susd5 sushi domain containing 5 increases expression ISO Isotretinoin results in increased expression of SUSD5 mRNA CTD PMID:20436886 NCBI chr 8:113,996,771...114,036,133
Ensembl chr 8:113,997,362...114,035,861 		JBrowse link
G Syn2 synapsin II decreases expression ISO Isotretinoin results in decreased expression of SYN2 mRNA CTD PMID:20436886 NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192 		JBrowse link
G Syngr1 synaptogyrin 1 decreases expression ISO Isotretinoin results in decreased expression of SYNGR1 mRNA CTD PMID:20436886 NCBI chr 7:111,635,911...111,659,341
Ensembl chr 7:111,635,918...111,659,341 		JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 increases expression ISO Isotretinoin results in increased expression of TACSTD2 mRNA CTD PMID:15982314 NCBI chr 4:96,707,950...96,709,650
Ensembl chr 4:96,707,951...96,709,650 		JBrowse link
G Tagln transgelin increases expression
multiple interactions		 ISO Isotretinoin results in increased expression of TAGLN mRNA
[LAQ824 co-treated with Isotretinoin] results in increased expression of TAGLN mRNA		 CTD PMID:17237267 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668 		JBrowse link
G Tagln3 transgelin 3 decreases expression ISO Isotretinoin results in decreased expression of TAGLN3 mRNA CTD PMID:20436886 NCBI chr11:55,099,887...55,113,457
Ensembl chr11:55,099,743...55,113,485 		JBrowse link
G Taldo1 transaldolase 1 decreases expression ISO Isotretinoin results in decreased expression of TALDO1 mRNA CTD PMID:20436886 NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974 		JBrowse link
G Tbc1d1 TBC1 domain family member 1 increases expression ISO Isotretinoin results in increased expression of TBC1D1 mRNA CTD PMID:20436886 NCBI chr14:43,936,820...44,135,133
Ensembl chr14:43,935,636...44,136,499 		JBrowse link
G Tbl1xr1 TBL1X/Y related 1 increases expression ISO Isotretinoin results in increased expression of TBL1XR1 mRNA CTD PMID:20436886 NCBI chr 2:104,788,950...104,929,055
Ensembl chr 2:104,801,721...104,929,055 		JBrowse link
G Tcf15 transcription factor 15 decreases expression ISO Isotretinoin results in decreased expression of TCF15 mRNA CTD PMID:31711903 NCBI chr 3:140,638,984...140,644,766
Ensembl chr 3:140,638,984...140,644,766 		JBrowse link
G Tcta T-cell leukemia translocation altered decreases expression ISO Isotretinoin results in decreased expression of TCTA mRNA CTD PMID:20436886 NCBI chr 8:108,988,588...108,992,324
Ensembl chr 8:108,988,590...108,991,564 		JBrowse link
G Tecr trans-2,3-enoyl-CoA reductase decreases expression ISO Isotretinoin results in decreased expression of TECR mRNA CTD PMID:20436886 NCBI chr19:24,526,705...24,568,168
Ensembl chr19:24,541,615...24,568,168 		JBrowse link
G Tent5c terminal nucleotidyltransferase 5C decreases expression ISO Isotretinoin results in decreased expression of TENT5C mRNA CTD PMID:20436886 NCBI chr 2:187,853,026...187,875,260
Ensembl chr 2:187,853,024...187,894,744 		JBrowse link
G Tert telomerase reverse transcriptase decreases expression ISO Isotretinoin results in decreased expression of TERT mRNA CTD PMID:16180984 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tfdp2 transcription factor Dp-2 decreases expression ISO Isotretinoin results in decreased expression of TFDP2 mRNA CTD PMID:20436886 NCBI chr 8:96,760,459...96,901,466
Ensembl chr 8:96,760,504...96,896,682 		JBrowse link
G Tff2 trefoil factor 2 decreases expression ISO Isotretinoin results in decreased expression of TFF2 mRNA CTD PMID:20436886 NCBI chr20:9,215,750...9,219,619
Ensembl chr20:9,215,761...9,219,619 		JBrowse link
G Tfrc transferrin receptor decreases expression ISO Isotretinoin results in decreased expression of TFRC mRNA CTD PMID:20436886 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression EXP Isotretinoin results in decreased expression of TGFB1 mRNA CTD PMID:15972972 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link