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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:isotretinoin
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Accession:CHEBI:6067 term browser browse the term
Definition:A retinoic acid that is all-trans-retinoic acid in which the double bond which is alpha,beta- to the carboxy group is isomerised to Z configuration. A synthetic retinoid, it is used for the treatment of severe cases of acne and other skin diseases.
Synonyms:exact_synonym: (2Z,4E6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
 related_synonym: (7E,9E,11E,13Z)-retinoic acid;   13-RA;   13-cis-Vitamin A acid;   13-cis-retinoic acid;   Accutane;   Amnesteem;   Claravis;   Formula=C20H28O2;   InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14-;   InChIKey=SHGAZHPCJJPHSC-XFYACQKRSA-N;   Neovitamin A acid;   SMILES=CC(\\C=C\\C1=C(C)CCCC1(C)C)=C/C=C/C(C)=C\\C(O)=O;   cis-RA;   isotretinoina;   isotretinoine;   isotretinoino;   isotretinoinum
 xref: Beilstein:1885770;   CAS:4759-48-2;   DrugBank:DB00982;   Drug_Central:1508;   HMDB:HMDB0006219;   KEGG:D00348;   LIPID_MAPS_instance:LMPR01090021
 xref_mesh: MESH:D015474
 xref: PMID:11606947;   PMID:11866680;   PMID:15304471;   PMID:18077132;   PMID:18788179;   PMID:19568610;   PMID:20482692;   PMID:23676507;   PMID:9807973;   Patent:EP111325;   Patent:US4556518;   Reaxys:1885770;   Wikipedia:Isotretinoin


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isotretinoin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin increases expression ISO Isotretinoin results in increased expression of A2M mRNA CTD PMID:20436886 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Aacs acetoacetyl-CoA synthetase decreases expression ISO Isotretinoin results in decreased expression of AACS mRNA CTD PMID:20436886 NCBI chr12:36,512,393...36,555,694
Ensembl chr12:36,512,393...36,555,694
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 increases expression EXP Isotretinoin results in increased expression of ABCA1 protein CTD PMID:17478430 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO [vorinostat co-treated with Isotretinoin] results in increased expression of ABCB1 mRNA CTD PMID:18769122 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 increases expression EXP Isotretinoin results in increased expression of ABCG1 protein CTD PMID:17478430 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
JBrowse link
G Abhd5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase decreases expression ISO Isotretinoin results in decreased expression of ABHD5 mRNA CTD PMID:20436886 NCBI chr 8:130,973,222...131,001,448
Ensembl chr 8:130,973,201...131,001,458
JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A decreases expression ISO Isotretinoin results in decreased expression of ACAA1 mRNA CTD PMID:20436886 NCBI chr 8:128,027,880...128,036,471
Ensembl chr 8:128,027,958...128,036,236
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 decreases expression ISO Isotretinoin results in decreased expression of ACAA2 mRNA CTD PMID:20436886 NCBI chr18:70,733,872...70,762,395
Ensembl chr18:70,733,872...70,762,395
JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases expression ISO Isotretinoin results in decreased expression of ACACA mRNA CTD PMID:20436886 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acad8 acyl-CoA dehydrogenase family, member 8 decreases expression ISO Isotretinoin results in decreased expression of ACAD8 mRNA CTD PMID:20436886 NCBI chr 8:28,023,401...28,044,967
Ensembl chr 8:28,024,123...28,044,876
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases expression ISO Isotretinoin results in decreased expression of ACADM mRNA CTD PMID:20436886 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain decreases expression ISO Isotretinoin results in decreased expression of ACADVL mRNA CTD PMID:20436886 NCBI chr10:56,619,321...56,624,468
Ensembl chr10:56,619,303...56,624,526
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 decreases expression ISO Isotretinoin results in decreased expression of ACAT2 mRNA CTD PMID:20436886 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
JBrowse link
G Acly ATP citrate lyase decreases expression ISO Isotretinoin results in decreased expression of ACLY mRNA CTD PMID:20436886 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Aco1 aconitase 1 decreases expression ISO Isotretinoin results in decreased expression of ACO1 mRNA CTD PMID:20436886 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
JBrowse link
G Acot13 acyl-CoA thioesterase 13 decreases expression ISO Isotretinoin results in decreased expression of ACOT13 mRNA CTD PMID:20436886 NCBI chr17:42,241,141...42,253,611
Ensembl chr17:42,241,159...42,253,649
JBrowse link
G Acot2 acyl-CoA thioesterase 2 decreases expression ISO Isotretinoin results in decreased expression of ACOT2 mRNA CTD PMID:20436886 NCBI chr 6:107,460,596...107,468,324
Ensembl chr 6:107,460,668...107,467,487
JBrowse link
G Acox2 acyl-CoA oxidase 2 decreases expression ISO Isotretinoin results in decreased expression of ACOX2 mRNA CTD PMID:20436886 NCBI chr15:18,449,304...18,481,472
Ensembl chr15:18,451,144...18,481,470
JBrowse link
G Acp6 acid phosphatase 6, lysophosphatidic decreases expression ISO Isotretinoin results in decreased expression of ACP6 mRNA CTD PMID:20436886 NCBI chr 2:199,284,177...199,305,793
Ensembl chr 2:199,283,909...199,305,799
JBrowse link
G Acsbg1 acyl-CoA synthetase bubblegum family member 1 decreases expression ISO Isotretinoin results in decreased expression of ACSBG1 mRNA CTD PMID:20436886 NCBI chr 8:59,184,111...59,240,133
Ensembl chr 8:59,184,113...59,239,954
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression ISO Isotretinoin results in decreased expression of ACSL3 mRNA CTD PMID:20436886 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression ISO Isotretinoin results in decreased expression of ACSL5 mRNA CTD PMID:20436886 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 decreases expression ISO Isotretinoin results in decreased expression of SAH mRNA CTD PMID:20436886 NCBI chr 1:189,514,504...189,541,233
Ensembl chr 1:189,514,553...189,541,224
JBrowse link
G Acy1 aminoacylase 1 decreases expression ISO Isotretinoin results in decreased expression of ACY1 mRNA CTD PMID:20436886 NCBI chr 8:115,134,792...115,140,171
Ensembl chr 8:115,134,765...115,140,080
JBrowse link
G Adgra2 adhesion G protein-coupled receptor A2 increases expression ISO Isotretinoin results in increased expression of ADGRA2 mRNA CTD PMID:20436886 NCBI chr16:69,094,587...69,133,015
Ensembl chr16:69,095,936...69,132,584
JBrowse link
G Adgre5 adhesion G protein-coupled receptor E5 increases expression ISO Isotretinoin results in increased expression of ADGRE5 mRNA CTD PMID:20436886 NCBI chr19:24,854,981...24,875,712
Ensembl chr19:24,855,299...24,875,137
JBrowse link
G Adgrg2 adhesion G protein-coupled receptor G2 decreases expression ISO Isotretinoin results in decreased expression of ADGRG2 mRNA CTD PMID:20436886 NCBI chr  X:36,930,186...37,054,968
Ensembl chr  X:36,930,186...37,003,642
JBrowse link
G Adra2a adrenoceptor alpha 2A increases expression ISO Isotretinoin results in increased expression of ADRA2A mRNA CTD PMID:20436886 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein decreases expression ISO Isotretinoin results in decreased expression of ADTRP mRNA CTD PMID:20436886 NCBI chr17:22,619,913...22,688,296
Ensembl chr17:22,619,891...22,688,307
JBrowse link
G Aga aspartylglucosaminidase decreases expression ISO Isotretinoin results in decreased expression of AGA mRNA CTD PMID:20436886 NCBI chr16:41,222,225...41,234,169
Ensembl chr16:41,222,238...41,234,095
JBrowse link
G Agpat3 1-acylglycerol-3-phosphate O-acyltransferase 3 decreases expression ISO Isotretinoin results in decreased expression of AGPAT3 mRNA CTD PMID:20436886 NCBI chr20:11,060,584...11,144,806
Ensembl chr20:11,114,164...11,144,806
JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member decreases expression ISO Isotretinoin results in decreased expression of AGR2 mRNA CTD PMID:20436886 NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714
JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression EXP Isotretinoin results in increased expression of AGTR1 mRNA; Isotretinoin results in increased expression of AGTR1 protein CTD PMID:19212007 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Ahsp alpha hemoglobin stabilizing protein decreases expression ISO Isotretinoin results in decreased expression of AHSP mRNA CTD PMID:20436886 NCBI chr 1:199,720,038...199,721,010
Ensembl chr 1:199,720,038...199,721,010
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 decreases expression ISO Isotretinoin results in decreased expression of AIFM1 mRNA CTD PMID:20436886 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Aip aryl-hydrocarbon receptor-interacting protein decreases expression ISO Isotretinoin results in decreased expression of AIP mRNA CTD PMID:15982314 NCBI chr 1:219,361,859...219,373,924
Ensembl chr 1:219,361,860...219,374,014
JBrowse link
G Akap11 A-kinase anchoring protein 11 increases expression ISO Isotretinoin results in increased expression of AKAP11 mRNA CTD PMID:20436886 NCBI chr15:60,722,138...60,766,673
Ensembl chr15:60,722,160...60,766,579
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 decreases expression ISO Isotretinoin results in decreased expression of AKR1A1 mRNA CTD PMID:20436886 NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 decreases expression ISO Isotretinoin results in decreased expression of ALAS1 mRNA CTD PMID:20436886 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177
JBrowse link
G Alb albumin decreases expression EXP Isotretinoin results in decreased expression of ALB protein CTD PMID:16092084 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Alcam activated leukocyte cell adhesion molecule decreases expression ISO Isotretinoin results in decreased expression of ALCAM mRNA CTD PMID:20436886 NCBI chr11:50,780,735...50,985,083
Ensembl chr11:50,781,127...50,985,083
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases expression ISO Isotretinoin results in decreased expression of ALDH1A2 mRNA CTD PMID:31711903 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link
G Aldh3b2 aldehyde dehydrogenase 3 family, member B2 decreases expression ISO Isotretinoin results in decreased expression of ALDH3B2 mRNA CTD PMID:20436886 NCBI chr 1:219,215,023...219,218,488 JBrowse link
G Alg13 ALG13, UDP-N-acetylglucosaminyltransferase subunit decreases expression ISO Isotretinoin results in decreased expression of ALG13 mRNA CTD PMID:20436886 NCBI chr  X:115,561,329...115,589,792
Ensembl chr  X:115,561,332...115,619,505
JBrowse link
G Alox15b arachidonate 15-lipoxygenase, type B decreases expression ISO Isotretinoin results in decreased expression of ALOX15B mRNA CTD PMID:20436886 NCBI chr10:55,773,748...55,783,489
Ensembl chr10:55,774,006...55,783,489
JBrowse link
G Amacr alpha-methylacyl-CoA racemase decreases expression ISO Isotretinoin results in decreased expression of AMACR mRNA CTD PMID:20436886 NCBI chr 2:60,949,276...60,961,342
Ensembl chr 2:60,949,256...60,961,326
JBrowse link
G Ank2 ankyrin 2 increases expression ISO Isotretinoin results in increased expression of ANK2 mRNA CTD PMID:20436886 NCBI chr 2:231,224,643...231,522,655
Ensembl chr 2:231,226,949...231,648,122
JBrowse link
G Ankhd1 ankyrin repeat and KH domain containing 1 decreases expression ISO Isotretinoin results in decreased expression of ANKHD1 mRNA CTD PMID:20436886 NCBI chr18:29,386,906...29,485,611
Ensembl chr18:29,386,809...29,492,718
JBrowse link
G Ano10 anoctamin 10 decreases expression ISO Isotretinoin results in decreased expression of ANO10 mRNA CTD PMID:20436886 NCBI chr 8:130,812,941...130,931,021
Ensembl chr 8:130,813,214...130,930,990
JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 increases expression ISO Isotretinoin results in increased expression of AP2B1 mRNA CTD PMID:20436886 NCBI chr10:70,516,462...70,621,973
Ensembl chr10:70,520,206...70,621,977
JBrowse link
G Ap3s2 adaptor related protein complex 3 subunit sigma 2 decreases expression ISO Isotretinoin results in decreased expression of AP3S2 mRNA CTD PMID:20436886 NCBI chr 1:141,612,961...141,655,417
Ensembl chr 1:141,612,963...141,655,894
JBrowse link
G Apoc1 apolipoprotein C1 decreases expression ISO Isotretinoin results in decreased expression of APOC1 mRNA CTD PMID:20436886 NCBI chr 1:80,606,638...80,609,921
Ensembl chr 1:80,606,638...80,609,921
JBrowse link
G Apoe apolipoprotein E affects response to substance ISO APOE gene polymorphism affects the susceptibility to Isotretinoin CTD PMID:12622636 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Apool apolipoprotein O-like decreases expression ISO Isotretinoin results in decreased expression of APOOL mRNA CTD PMID:20436886 NCBI chr  X:83,678,269...83,750,550
Ensembl chr  X:83,678,339...83,750,549
JBrowse link
G Areg amphiregulin multiple interactions ISO Isotretinoin inhibits the reaction [Calcitriol results in increased expression of AREG mRNA] CTD PMID:11237771 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arg2 arginase 2 decreases expression ISO Isotretinoin results in decreased expression of ARG2 mRNA CTD PMID:20436886 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases expression ISO Isotretinoin results in increased expression of ARHGDIB mRNA CTD PMID:20436886 NCBI chr 4:170,913,920...170,932,789
Ensembl chr 4:170,913,923...170,932,618
JBrowse link
G Arhgef6 Rac/Cdc42 guanine nucleotide exchange factor 6 increases expression ISO Isotretinoin results in increased expression of ARHGEF6 mRNA CTD PMID:20436886 NCBI chr  X:159,722,031...159,841,344
Ensembl chr  X:159,723,866...159,841,072
JBrowse link
G Artn artemin multiple interactions ISO [vorinostat co-treated with Isotretinoin] results in increased expression of ARTN mRNA CTD PMID:18769122 NCBI chr 5:136,759,717...136,765,036
Ensembl chr 5:136,759,717...136,762,986
JBrowse link
G Asap3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 increases expression ISO Isotretinoin results in increased expression of ASAP3 mRNA CTD PMID:20436886 NCBI chr 5:154,551,901...154,596,125
Ensembl chr 5:154,552,195...154,594,785
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO Isotretinoin affects the localization of and results in decreased activity of ATF2 protein CTD PMID:18652567 PMID:19066126 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atf5 activating transcription factor 5 multiple interactions ISO [vorinostat co-treated with Isotretinoin] results in decreased expression of ATF5 mRNA CTD PMID:18769122 NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522
JBrowse link
G Atg4a autophagy related 4A, cysteine peptidase decreases expression ISO Isotretinoin results in decreased expression of ATG4A mRNA CTD PMID:20436886 NCBI chr  X:112,328,907...112,403,157 JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 increases expression ISO Isotretinoin results in increased expression of ATP2B4 mRNA CTD PMID:20436886 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma decreases expression ISO Isotretinoin results in decreased expression of ATP5F1C mRNA CTD PMID:20436886 NCBI chr17:72,209,321...72,231,562
Ensembl chr17:72,209,373...72,394,271
JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 decreases expression ISO Isotretinoin results in decreased expression of ATP5MC3 mRNA CTD PMID:20436886 NCBI chr 3:60,811,218...60,813,903
Ensembl chr 3:60,811,210...60,813,869
JBrowse link
G Atp5mf ATP synthase membrane subunit f decreases expression ISO Isotretinoin results in decreased expression of ATP5MF mRNA CTD PMID:20436886 NCBI chr12:11,191,799...11,198,369
Ensembl chr12:11,191,812...11,198,369
JBrowse link
G Atp5mj ATP synthase membrane subunit j decreases expression ISO Isotretinoin results in decreased expression of ATP5MJ mRNA CTD PMID:20436886
G Atp6v0b ATPase H+ transporting V0 subunit B decreases expression ISO Isotretinoin results in decreased expression of ATP6V0B mRNA CTD PMID:20436886 NCBI chr 5:136,718,352...136,719,868
Ensembl chr 5:136,718,352...136,721,379
JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C decreases expression ISO Isotretinoin results in decreased expression of ATP6V0C mRNA CTD PMID:20436886 NCBI chr10:13,537,031...13,543,407
Ensembl chr10:13,537,033...13,542,077
JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D decreases expression ISO Isotretinoin results in decreased expression of ATP6V1D mRNA CTD PMID:20436886 NCBI chr 6:102,032,271...102,047,754
Ensembl chr 6:102,032,276...102,047,758
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression ISO Isotretinoin results in increased expression of BASP1 mRNA CTD PMID:20436886 NCBI chr 2:77,586,424...77,632,626
Ensembl chr 2:77,586,424...77,632,628
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Isotretinoin results in increased expression of BAX; Isotretinoin results in increased expression of BAX protein CTD PMID:16109544 PMID:16135400 PMID:16909596 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcap29 B-cell receptor-associated protein 29 decreases expression ISO Isotretinoin results in decreased expression of BCAP29 mRNA CTD PMID:20436886 NCBI chr 6:50,883,758...50,923,743
Ensembl chr 6:50,883,787...50,923,510
JBrowse link
G Bcap31 B-cell receptor-associated protein 31 decreases expression ISO Isotretinoin results in decreased expression of BCAP31 mRNA CTD PMID:20436886 NCBI chr  X:157,094,365...157,126,397
Ensembl chr  X:157,095,937...157,126,393
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 decreases expression ISO Isotretinoin results in decreased expression of BCAT2 mRNA CTD PMID:20436886 NCBI chr 1:101,553,900...101,572,103
Ensembl chr 1:101,554,642...101,572,080
JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta decreases expression ISO Isotretinoin results in decreased expression of BCKDHB mRNA CTD PMID:20436886 NCBI chr 8:91,464,229...91,656,134
Ensembl chr 8:91,464,229...91,656,134
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
increases expression
ISO Isotretinoin results in decreased expression of BCL2; Isotretinoin results in decreased expression of BCL2 protein
Isotretinoin results in decreased expression of BCL2; Isotretinoin results in decreased expression of BCL2 mRNA
Isotretinoin results in increased expression of BCL2 mRNA; Isotretinoin results in increased expression of BCL2 protein
CTD PMID:16109544 PMID:16909596 PMID:18380168 PMID:18652567 PMID:21159604 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
decreases expression
ISO Isotretinoin results in increased expression of BCL2L1 mRNA; Isotretinoin results in increased expression of BCL2L1 protein
Isotretinoin results in decreased expression of BCL2L1 protein
CTD PMID:16135400 PMID:21159604 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 decreases expression ISO Isotretinoin results in decreased expression of BDH1 mRNA CTD PMID:20436886 NCBI chr11:72,577,547...72,619,435
Ensembl chr11:72,578,533...72,614,176
JBrowse link
G Bean1 brain expressed, associated with NEDD4, 1 decreases expression ISO Isotretinoin results in decreased expression of BEAN1 mRNA CTD PMID:20436886 NCBI chr19:947,862...993,467
Ensembl chr19:949,607...983,556
JBrowse link
G Bend5 BEN domain containing 5 increases expression ISO Isotretinoin results in increased expression of BEND5 mRNA CTD PMID:20436886 NCBI chr 5:131,257,127...131,312,335
Ensembl chr 5:131,257,127...131,312,335
JBrowse link
G Bgn biglycan increases expression ISO Isotretinoin results in increased expression of BGN mRNA CTD PMID:20436886 NCBI chr  X:157,319,042...157,331,204
Ensembl chr  X:157,319,046...157,331,204
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO Isotretinoin results in increased expression of BHLHE40 mRNA CTD PMID:18769122 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO Isotretinoin results in decreased expression of BIRC5 protein CTD PMID:16135400 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Blvrb biliverdin reductase B decreases expression ISO Isotretinoin results in decreased expression of BLVRB mRNA CTD PMID:20436886 NCBI chr 1:84,256,063...84,273,726
Ensembl chr 1:84,256,159...84,274,075
JBrowse link
G Bmerb1 bMERB domain containing 1 increases expression ISO Isotretinoin results in increased expression of BMERB1 mRNA CTD PMID:20436886 NCBI chr10:3,411,380...3,570,689
Ensembl chr10:3,411,380...3,570,688
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase decreases expression ISO Isotretinoin results in decreased expression of BRAF mRNA CTD PMID:20436886 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356
JBrowse link
G Bsg basigin (Ok blood group) decreases expression ISO Isotretinoin results in decreased expression of BSG mRNA CTD PMID:20436886 NCBI chr 7:12,875,536...12,882,753
Ensembl chr 7:12,875,537...12,882,753
JBrowse link
G Btbd3 BTB domain containing 3 increases expression ISO Isotretinoin results in increased expression of BTBD3 mRNA CTD PMID:20436886 NCBI chr 3:131,330,338...131,360,554
Ensembl chr 3:131,351,587...131,357,929
JBrowse link
G Btd biotinidase decreases expression ISO Isotretinoin results in decreased expression of BTD mRNA CTD PMID:20436886 NCBI chr16:7,758,192...7,791,301
Ensembl chr16:7,758,996...7,791,243
JBrowse link
G C1r complement C1r increases expression ISO Isotretinoin results in increased expression of C1R mRNA CTD PMID:20436886 NCBI chr 4:157,126,060...157,136,825
Ensembl chr 4:157,125,998...157,136,829
JBrowse link
G C1s complement C1s increases expression ISO Isotretinoin results in increased expression of C1S mRNA CTD PMID:20436886 NCBI chr 4:157,143,592...157,155,592
Ensembl chr 4:157,143,592...157,155,609
JBrowse link
G C3 complement C3 increases expression ISO Isotretinoin results in increased expression of C3 mRNA CTD PMID:20436886 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Cald1 caldesmon 1 increases expression ISO Isotretinoin results in increased expression of CALD1 mRNA CTD PMID:20436886 NCBI chr 4:62,103,948...62,291,375
Ensembl chr 4:62,220,736...62,291,489
JBrowse link
G Calml3 calmodulin-like 3 decreases expression ISO Isotretinoin results in decreased expression of CALML3 mRNA CTD PMID:20436886 NCBI chr17:70,070,458...70,073,697
Ensembl chr17:70,072,156...70,073,530
JBrowse link
G Casp3 caspase 3 increases cleavage
increases expression
ISO Isotretinoin results in increased cleavage of CASP3 protein
Isotretinoin results in increased expression of CASP3; Isotretinoin results in increased expression of CASP3 mRNA
Isotretinoin results in increased expression of CASP3; Isotretinoin results in increased expression of CASP3 protein
CTD PMID:16109544 PMID:16135400 PMID:16157052 PMID:16575387 PMID:16909596 PMID:18380168 PMID:18652567 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases cleavage ISO Isotretinoin results in increased cleavage of CASP8 protein CTD PMID:16135400 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cat catalase multiple interactions ISO Isotretinoin inhibits the reaction [Benzoyl Peroxide results in decreased activity of CAT protein] CTD PMID:15225900 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cavin1 caveolae associated protein 1 increases expression ISO Isotretinoin results in increased expression of CAVIN1 mRNA CTD PMID:20436886 NCBI chr10:88,862,513...88,874,495
Ensembl chr10:88,860,733...88,874,528
JBrowse link
G Cbx3 chromobox 3 decreases expression ISO Isotretinoin results in decreased expression of CBX3 mRNA CTD PMID:15982314 NCBI chr 4:81,243,809...81,257,898
Ensembl chr 4:81,244,469...81,257,897
JBrowse link
G Ccdc86 coiled-coil domain containing 86 decreases expression ISO Isotretinoin results in decreased expression of CCDC86 mRNA CTD PMID:20436886 NCBI chr 1:226,996,435...227,002,016
Ensembl chr 1:226,996,237...227,002,139
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression EXP Isotretinoin results in decreased expression of CCL2 mRNA CTD PMID:15972972 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression EXP Isotretinoin results in decreased expression of CCL3 mRNA CTD PMID:15972972 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions
decreases expression
ISO
EXP
Isotretinoin inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; Isotretinoin inhibits the reaction [TNF protein results in increased secretion of CCL5 protein]
Isotretinoin results in decreased expression of CCL5 mRNA
CTD PMID:15972972 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Isotretinoin results in decreased expression of CCND1 protein CTD PMID:16575387 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cd2 Cd2 molecule increases expression ISO Isotretinoin results in increased expression of CD2 mRNA CTD PMID:20436886 NCBI chr 2:203,666,706...203,680,073
Ensembl chr 2:203,666,637...203,680,083
JBrowse link
G Cd247 Cd247 molecule increases expression ISO Isotretinoin results in increased expression of CD3Z mRNA CTD PMID:20436886 NCBI chr13:83,996,045...84,071,408
Ensembl chr13:83,996,080...84,071,400
JBrowse link
G Cd34 CD34 molecule increases expression ISO Isotretinoin results in increased expression of CD34 mRNA CTD PMID:20436886 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647
JBrowse link
G Cd37 CD37 molecule increases expression ISO Isotretinoin results in increased expression of CD37 mRNA CTD PMID:20436886 NCBI chr 1:101,230,470...101,236,061
Ensembl chr 1:101,230,533...101,236,065
JBrowse link
G Cd38 CD38 molecule increases expression ISO Isotretinoin results in increased expression of CD38 protein CTD PMID:16275619 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672
JBrowse link
G Cd3d CD3d molecule increases expression ISO Isotretinoin results in increased expression of CD3D mRNA CTD PMID:20436886 NCBI chr 8:49,282,502...49,287,095
Ensembl chr 8:49,282,460...49,287,110
JBrowse link
G Cd52 CD52 molecule increases expression ISO Isotretinoin results in increased expression of CD52 mRNA CTD PMID:20436886 NCBI chr 5:152,322,910...152,324,469
Ensembl chr 5:152,322,916...152,324,469
JBrowse link
G Cd69 Cd69 molecule multiple interactions ISO [Dacarbazine co-treated with Isotretinoin] affects the reaction [IFNA2 protein results in increased expression of CD69 protein] CTD PMID:17973783 NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084
JBrowse link
G Cd81 Cd81 molecule increases expression ISO Isotretinoin results in increased expression of CD81 mRNA CTD PMID:20436886 NCBI chr 1:216,237,663...216,253,460
Ensembl chr 1:216,237,697...216,253,311
JBrowse link
G Cda cytidine deaminase decreases expression ISO Isotretinoin results in decreased expression of CDA mRNA CTD PMID:20436886 NCBI chr 5:156,703,579...156,734,541
Ensembl chr 5:156,703,579...156,734,541
JBrowse link
G Cdc14b cell division cycle 14B increases expression ISO Isotretinoin results in increased expression of CDC14B mRNA CTD PMID:20436886 NCBI chr17:1,709,703...1,797,732
Ensembl chr17:1,703,943...1,797,750
JBrowse link
G Cdh5 cadherin 5 increases expression ISO Isotretinoin results in increased expression of CDH5 mRNA CTD PMID:18769122 NCBI chr19:1,025,122...1,074,333
Ensembl chr19:1,023,683...1,074,365
JBrowse link
G Cdk5 cyclin-dependent kinase 5 decreases expression ISO Isotretinoin results in decreased expression of CDK5 mRNA CTD PMID:20436886 NCBI chr 4:7,282,945...7,287,427
Ensembl chr 4:7,282,948...7,288,383
JBrowse link
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 decreases expression ISO Isotretinoin results in decreased expression of CDK5RAP1 mRNA CTD PMID:20436886 NCBI chr 3:149,835,953...149,870,429
Ensembl chr 3:149,703,848...149,870,413
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression
multiple interactions
increases expression
ISO Isotretinoin results in decreased expression of CDKN1A mRNA
[LAQ824 co-treated with Isotretinoin] results in increased expression of CDKN1A mRNA; [LAQ824 co-treated with Isotretinoin] results in increased expression of CDKN1A protein
Isotretinoin results in increased expression of CDKN1A protein
CTD PMID:16575387 PMID:17237267 PMID:20436886 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression ISO Isotretinoin results in decreased expression of CDKN1C mRNA CTD PMID:15982314 NCBI chr 1:216,661,067...216,663,791
Ensembl chr 1:216,661,080...216,663,721
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 decreases expression ISO Isotretinoin results in decreased expression of CEACAM1 mRNA CTD PMID:20436886 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Cel carboxyl ester lipase increases expression ISO Isotretinoin results in increased expression of CEL mRNA CTD PMID:18769122 NCBI chr 3:7,134,021...7,141,522
Ensembl chr 3:7,134,021...7,141,522
JBrowse link
G Celf2 CUGBP, Elav-like family member 2 increases expression ISO Isotretinoin results in increased expression of CELF2 mRNA CTD PMID:20436886 NCBI chr17:75,259,269...75,660,154
Ensembl chr17:75,352,389...75,654,951
JBrowse link
G Cers4 ceramide synthase 4 decreases expression ISO Isotretinoin results in decreased expression of CERS4 mRNA CTD PMID:20436886 NCBI chr12:4,439,750...4,474,759
Ensembl chr12:4,439,750...4,474,729
JBrowse link
G Cfap45 cilia and flagella associated protein 45 decreases expression ISO Isotretinoin results in decreased expression of CFAP45 mRNA CTD PMID:20436886 NCBI chr13:90,909,551...90,932,958
Ensembl chr13:90,909,486...90,932,961
JBrowse link
G Chi3l1 chitinase 3 like 1 decreases expression ISO Isotretinoin results in decreased expression of CHI3L1 mRNA CTD PMID:20436886 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802
JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 decreases expression ISO Isotretinoin results in decreased expression of CHP1 mRNA CTD PMID:20436886 NCBI chr 3:111,354,506...111,389,998
Ensembl chr 3:111,354,506...111,389,989
JBrowse link
G Chst5 carbohydrate sulfotransferase 5 increases expression ISO Isotretinoin results in increased expression of CHST6 mRNA CTD PMID:20436886 NCBI chr19:44,115,065...44,136,092
Ensembl chr19:44,115,120...44,135,387
JBrowse link
G Cidea cell death-inducing DFFA-like effector a decreases expression ISO Isotretinoin results in decreased expression of CIDEA mRNA CTD PMID:20436886 NCBI chr18:63,082,861...63,108,450
Ensembl chr18:63,098,144...63,108,051
JBrowse link
G Ckb creatine kinase B decreases expression ISO Isotretinoin results in decreased expression of CKB mRNA CTD PMID:15982314 NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
JBrowse link
G Ckm creatine kinase, M-type increases expression ISO Isotretinoin results in increased expression of CKM protein CTD PMID:9747221 NCBI chr 1:80,321,507...80,331,841
Ensembl chr 1:80,321,585...80,331,841
JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1 decreases expression ISO Isotretinoin results in decreased expression of CKMT1 mRNA CTD PMID:20436886 NCBI chr 3:113,318,559...113,324,459
Ensembl chr 3:113,318,563...113,324,461
JBrowse link
G Clcn3 chloride voltage-gated channel 3 decreases expression ISO Isotretinoin results in decreased expression of CLCN3 mRNA CTD PMID:20436886 NCBI chr16:32,448,821...32,520,649
Ensembl chr16:32,449,116...32,519,148
JBrowse link
G Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit X decreases expression ISO Isotretinoin results in decreased expression of CLPX mRNA CTD PMID:20436886 NCBI chr 8:70,789,137...70,843,133
Ensembl chr 8:70,789,256...70,843,123
JBrowse link
G Clstn3 calsyntenin 3 decreases expression ISO Isotretinoin results in decreased expression of CLSTN3 mRNA CTD PMID:20436886 NCBI chr 4:157,044,736...157,078,013
Ensembl chr 4:157,043,925...157,078,130
JBrowse link
G Cndp2 carnosine dipeptidase 2 decreases expression ISO Isotretinoin results in decreased expression of CNDP2 mRNA CTD PMID:20436886 NCBI chr18:81,521,966...81,539,065
Ensembl chr18:81,521,968...81,539,065
JBrowse link
G Coch cochlin increases expression ISO Isotretinoin results in increased expression of COCH mRNA CTD PMID:20436886 NCBI chr 6:72,359,702...72,373,710
Ensembl chr 6:72,359,791...72,373,695
JBrowse link
G Col14a1 collagen type XIV alpha 1 chain increases expression ISO Isotretinoin results in increased expression of COL14A1 mRNA CTD PMID:20436886 NCBI chr 7:95,054,877...95,274,073
Ensembl chr 7:95,074,236...95,273,298
JBrowse link
G Col17a1 collagen type XVII alpha 1 chain decreases expression ISO Isotretinoin results in decreased expression of COL17A1 mRNA CTD PMID:15982314 NCBI chr 1:267,416,681...267,465,049
Ensembl chr 1:267,417,459...267,463,705
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression EXP Isotretinoin results in decreased expression of COL1A1 mRNA; Isotretinoin results in decreased expression of COL1A1 protein CTD PMID:15972972 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression EXP Isotretinoin results in decreased expression of COL3A1 mRNA; Isotretinoin results in decreased expression of COL3A1 protein CTD PMID:15972972 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Col4a2 collagen type IV alpha 2 chain increases expression ISO Isotretinoin results in increased expression of COL4A2 mRNA CTD PMID:20436886 NCBI chr16:83,386,388...83,522,169
Ensembl chr16:83,387,364...83,438,561
JBrowse link
G Col5a1 collagen type V alpha 1 chain increases expression ISO Isotretinoin results in increased expression of COL5A1 mRNA CTD PMID:20436886 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
JBrowse link
G Col5a2 collagen type V alpha 2 chain increases expression ISO Isotretinoin results in increased expression of COL5A2 mRNA CTD PMID:20436886 NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564
JBrowse link
G Col6a1 collagen type VI alpha 1 chain decreases expression
increases expression
ISO Isotretinoin results in decreased expression of COL6A1 mRNA
Isotretinoin results in increased expression of COL6A1 mRNA
CTD PMID:15982314 PMID:20436886 NCBI chr20:12,657,913...12,676,370
Ensembl chr20:12,658,065...12,675,561
JBrowse link
G Col6a2 collagen type VI alpha 2 chain increases expression ISO Isotretinoin results in increased expression of COL6A2 mRNA CTD PMID:20436886 NCBI chr20:12,773,472...12,801,179
Ensembl chr20:12,773,427...12,801,180
JBrowse link
G Col6a3 collagen type VI alpha 3 chain increases expression ISO Isotretinoin results in increased expression of COL6A3 mRNA CTD PMID:20436886 NCBI chr 9:97,926,784...98,004,643
Ensembl chr 9:97,926,787...98,004,546
JBrowse link
G Col8a2 collagen type VIII alpha 2 chain decreases expression ISO Isotretinoin results in decreased expression of COL8A2 mRNA CTD PMID:15982314 NCBI chr 5:144,308,527...144,335,142
Ensembl chr 5:144,308,611...144,335,172
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A decreases expression ISO Isotretinoin results in decreased expression of COX5A mRNA CTD PMID:20436886 NCBI chr 8:62,298,358...62,309,765
Ensembl chr 8:62,298,358...62,309,765
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B decreases expression ISO Isotretinoin results in decreased expression of COX5B mRNA CTD PMID:20436886 NCBI chr 9:43,259,706...43,262,039
Ensembl chr 9:43,259,709...43,262,040
JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 decreases expression ISO Isotretinoin results in decreased expression of COX6A1 mRNA CTD PMID:20436886 NCBI chr12:47,024,442...47,027,495
Ensembl chr12:47,024,442...47,027,495
JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 decreases expression ISO Isotretinoin results in decreased expression of COX7A2 mRNA CTD PMID:20436886 NCBI chr 8:87,209,529...87,213,627
Ensembl chr 8:87,209,530...87,213,627
JBrowse link
G Cox7b cytochrome c oxidase subunit 7B decreases expression ISO Isotretinoin results in decreased expression of COX7B mRNA CTD PMID:20436886 NCBI chr  X:77,065,427...77,071,676
Ensembl chr  X:77,065,397...77,071,676
JBrowse link
G Cpd carboxypeptidase D decreases expression ISO Isotretinoin results in decreased expression of CPD mRNA CTD PMID:20436886 NCBI chr10:63,325,764...63,389,811
Ensembl chr10:63,325,199...63,389,817
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 decreases expression ISO Isotretinoin results in decreased expression of CPT2 mRNA CTD PMID:20436886 NCBI chr 5:127,505,646...127,523,016
Ensembl chr 5:127,505,614...127,523,089
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression
multiple interactions
ISO Isotretinoin results in increased expression of CRABP2 mRNA
R116010 promotes the reaction [Isotretinoin results in increased expression of CRABP2 mRNA]
CTD PMID:17486130 NCBI chr 2:187,322,416...187,326,794
Ensembl chr 2:184,882,969...184,883,505
JBrowse link
G Crat carnitine O-acetyltransferase decreases expression ISO Isotretinoin results in decreased expression of CRAT mRNA CTD PMID:20436886 NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation ISO Isotretinoin results in increased phosphorylation of CREB1 protein CTD PMID:16280361 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Cript CXXC repeat containing interactor of PDZ3 domain decreases expression ISO Isotretinoin results in decreased expression of CRIPT mRNA CTD PMID:20436886 NCBI chr 6:10,594,147...10,602,103
Ensembl chr 6:10,594,122...10,602,085
JBrowse link
G Crtc3 CREB regulated transcription coactivator 3 increases expression ISO Isotretinoin results in increased expression of CRTC3 mRNA CTD PMID:20436886 NCBI chr 1:142,398,248...142,500,562
Ensembl chr 1:142,393,207...142,500,383
JBrowse link
G Cryz crystallin zeta multiple interactions ISO Isotretinoin inhibits the reaction [Benzoyl Peroxide results in decreased activity of CRYZ protein] CTD PMID:15225900 NCBI chr 2:260,884,315...260,911,827
Ensembl chr 2:260,884,337...260,911,792
JBrowse link
G Csf1r colony stimulating factor 1 receptor increases expression ISO Isotretinoin results in increased expression of CSF1R mRNA CTD PMID:20436886 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Csf2 colony stimulating factor 2 decreases secretion EXP Isotretinoin results in decreased secretion of CSF2 protein CTD PMID:15972972 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Cst3 cystatin C increases expression ISO Isotretinoin results in increased expression of CST3 mRNA CTD PMID:20436886 NCBI chr 3:143,219,671...143,223,544
Ensembl chr 3:143,219,686...143,223,615
JBrowse link
G Cstb cystatin B decreases expression ISO Isotretinoin results in decreased expression of CSTB mRNA CTD PMID:20436886 NCBI chr20:10,966,357...10,968,399
Ensembl chr20:10,966,331...10,968,432
JBrowse link
G Cth cystathionine gamma-lyase decreases expression ISO Isotretinoin results in decreased expression of CTH mRNA CTD PMID:20436886 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Cttn cortactin decreases expression ISO Isotretinoin results in decreased expression of CTTN mRNA CTD PMID:20436886 NCBI chr 1:217,602,698...217,638,196
NCBI chr 1:215,255,385...215,290,882
Ensembl chr 1:217,602,698...217,638,152
Ensembl chr 1:217,602,698...217,638,152
JBrowse link
G Cux2 cut-like homeobox 2 decreases expression ISO Isotretinoin results in decreased expression of CUX2 mRNA CTD PMID:20436886 NCBI chr12:40,016,774...40,221,067
Ensembl chr12:40,018,937...40,219,291
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 decreases expression ISO Isotretinoin results in decreased expression of CXCL1 mRNA CTD PMID:15982314 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression ISO
EXP
Isotretinoin results in decreased expression of CXCL10 mRNA CTD PMID:15972972 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO Isotretinoin results in increased expression of CXCL12 mRNA CTD PMID:20436886 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression ISO Isotretinoin results in decreased expression of CXCL1 mRNA CTD PMID:15982314 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cyb5a cytochrome b5 type A decreases expression ISO Isotretinoin results in decreased expression of CYB5A mRNA CTD PMID:20436886 NCBI chr18:81,694,818...81,726,821
Ensembl chr18:81,694,808...81,726,821
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression ISO Isotretinoin results in increased expression of CYP26A1 mRNA CTD PMID:16194896 PMID:17486130 PMID:18769122 NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 multiple interactions
increases expression
ISO R116010 promotes the reaction [Isotretinoin results in increased expression of CYP26B1 mRNA] CTD PMID:17486130 PMID:18769122 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression ISO Isotretinoin results in decreased expression of CYP27A1 mRNA CTD PMID:15982314 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 increases activity
multiple interactions
ISO Isotretinoin results in increased activity of CYP3A4 protein
[Isotretinoin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; Isotretinoin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]
CTD PMID:16632523 PMID:25455453 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 decreases expression ISO Isotretinoin results in decreased expression of CYP4F3 mRNA CTD PMID:20436886 NCBI chr16:19,501,680...19,528,935
Ensembl chr16:19,410,810...19,528,999
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 decreases expression ISO Isotretinoin results in decreased expression of CYP4F8 mRNA CTD PMID:20436886 NCBI chr 7:15,198,950...15,225,547
Ensembl chr 7:15,198,940...15,225,410
JBrowse link
G Cyp51 cytochrome P450, family 51 decreases expression ISO Isotretinoin results in decreased expression of CYP51A1 mRNA CTD PMID:20436886 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein decreases expression ISO Isotretinoin results in decreased expression of DBI mRNA CTD PMID:20436886 NCBI chr13:36,147,667...36,156,076
Ensembl chr13:36,117,119...36,174,908
JBrowse link
G Dbn1 drebrin 1 increases expression ISO Isotretinoin results in increased expression of DBN1 mRNA CTD PMID:20436886 NCBI chr17:9,679,511...9,693,878
Ensembl chr17:9,679,628...9,693,820
JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 decreases expression ISO Isotretinoin results in decreased expression of DBT mRNA CTD PMID:20436886 NCBI chr 2:219,563,783...219,592,651
Ensembl chr 2:219,563,783...219,592,650
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase decreases expression ISO Isotretinoin results in decreased expression of DCXR mRNA CTD PMID:20436886 NCBI chr10:109,906,119...109,909,696
Ensembl chr10:109,906,815...109,909,715
JBrowse link
G Ddc dopa decarboxylase decreases expression ISO Isotretinoin results in decreased expression of DDC mRNA CTD PMID:20436886 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Ddo D-aspartate oxidase decreases expression ISO Isotretinoin results in decreased expression of DDO mRNA CTD PMID:20436886 NCBI chr20:48,739,812...48,758,958
Ensembl chr20:48,739,639...48,758,905
JBrowse link
G Ddt D-dopachrome tautomerase decreases expression ISO Isotretinoin results in decreased expression of DDT mRNA CTD PMID:20436886 NCBI chr20:13,827,153...13,829,624
Ensembl chr20:13,827,132...13,831,588
JBrowse link
G Dennd5a DENN domain containing 5A increases expression ISO Isotretinoin results in increased expression of DENND5A mRNA CTD PMID:20436886 NCBI chr 1:174,524,047...174,588,553
Ensembl chr 1:174,524,047...174,588,529
JBrowse link
G Desi1 desumoylating isopeptidase 1 decreases expression ISO Isotretinoin results in decreased expression of DESI1 mRNA CTD PMID:20436886 NCBI chr 7:123,238,332...123,259,636
Ensembl chr 7:123,238,333...123,259,636
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO Isotretinoin results in decreased expression of DHCR24 mRNA CTD PMID:20436886 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression ISO Isotretinoin results in decreased expression of DHCR7 mRNA CTD PMID:20436886 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904
JBrowse link
G Dhfr dihydrofolate reductase decreases expression ISO Isotretinoin results in decreased expression of DHFR mRNA CTD PMID:20436886 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
JBrowse link
G Dhrs11 dehydrogenase/reductase 11 decreases expression ISO Isotretinoin results in decreased expression of DHRS11 mRNA CTD PMID:20436886 NCBI chr10:72,144,042...72,153,496
Ensembl chr10:72,144,042...72,153,375
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases expression ISO Isotretinoin results in increased expression of DHRS3 mRNA CTD PMID:18769122 NCBI chr 5:162,809,090...162,843,385
Ensembl chr 5:162,808,646...162,843,383
JBrowse link
G Dhrs7b dehydrogenase/reductase 7B decreases expression ISO Isotretinoin results in decreased expression of DHRS7B mRNA CTD PMID:20436886 NCBI chr10:47,065,755...47,111,089
Ensembl chr10:47,065,850...47,111,101
JBrowse link
G Dhrs9 dehydrogenase/reductase 9 multiple interactions
decreases expression
ISO [vorinostat co-treated with Isotretinoin] results in increased expression of DHRS9 mRNA
Isotretinoin results in decreased expression of DHRS9 mRNA
CTD PMID:18769122 PMID:20436886 NCBI chr 3:55,623,671...55,645,883
Ensembl chr 3:55,623,634...55,648,325
JBrowse link
G Diras3 DIRAS family GTPase 3 decreases expression ISO Isotretinoin results in decreased expression of DIRAS3 mRNA CTD PMID:20436886 NCBI chr 6:135,938,345...135,940,205
Ensembl chr 6:135,938,935...135,939,534
JBrowse link
G Dixdc1 DIX domain containing 1 increases expression ISO Isotretinoin results in increased expression of DIXDC1 mRNA CTD PMID:20436886 NCBI chr 8:55,091,232...55,164,636
Ensembl chr 8:55,091,235...55,162,421
JBrowse link
G Dld dihydrolipoamide dehydrogenase decreases expression ISO Isotretinoin results in decreased expression of DLD mRNA CTD PMID:20436886 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694
JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 increases expression ISO Isotretinoin results in increased expression of DLG5 mRNA CTD PMID:20436886 NCBI chr15:120,213...230,312
Ensembl chr15:120,372...228,977
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase increases expression ISO Isotretinoin results in increased expression of DLST protein CTD PMID:15982314 NCBI chr 6:108,936,534...108,961,322
Ensembl chr 6:108,936,664...108,959,803
JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 decreases expression ISO Isotretinoin results in decreased expression of DNAJA3 mRNA CTD PMID:20436886 NCBI chr10:11,059,701...11,085,186
Ensembl chr10:11,060,313...11,085,210
JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 decreases expression ISO Isotretinoin results in decreased expression of DNAJC15 mRNA CTD PMID:20436886 NCBI chr15:59,990,131...60,056,710
Ensembl chr15:59,990,131...60,056,710
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 decreases expression ISO Isotretinoin results in decreased expression of DNAJC3 mRNA CTD PMID:20436886 NCBI chr15:104,186,918...104,226,236
Ensembl chr15:104,186,792...104,226,329
JBrowse link
G Dnase1 deoxyribonuclease 1 increases expression ISO Isotretinoin results in increased expression of DNASE1 protein CTD PMID:15982314 NCBI chr10:11,757,681...11,760,672
Ensembl chr10:11,757,682...11,760,620
JBrowse link
G Dnase1l2 deoxyribonuclease 1 like 2 decreases expression ISO Isotretinoin results in decreased expression of DNASE1L2 mRNA CTD PMID:20436886 NCBI chr10:13,812,335...13,814,514
Ensembl chr10:13,812,707...13,814,304
JBrowse link
G Dnm1 dynamin 1 increases expression ISO Isotretinoin results in increased expression of DNM1 mRNA CTD PMID:20436886 NCBI chr 3:11,338,081...11,382,043
Ensembl chr 3:11,338,083...11,382,043
JBrowse link
G Dop1b DOP1 leucine zipper like protein B decreases expression ISO Isotretinoin results in decreased expression of DOP1B mRNA CTD PMID:20436886 NCBI chr11:33,929,142...34,027,447
Ensembl chr11:33,925,498...34,027,435
JBrowse link
G Dpp3 dipeptidylpeptidase 3 decreases expression ISO Isotretinoin results in decreased expression of DPP3 mRNA CTD PMID:20436886 NCBI chr 1:220,166,124...220,189,762
Ensembl chr 1:220,166,127...220,188,541
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 increases expression ISO Isotretinoin results in increased expression of DPYSL2 mRNA CTD PMID:20436886 NCBI chr15:43,475,640...43,581,725
Ensembl chr15:43,477,629...43,542,939
JBrowse link
G Drp2 dystrophin related protein 2 decreases expression ISO Isotretinoin results in decreased expression of DRP2 mRNA CTD PMID:20436886 NCBI chr  X:105,239,623...105,290,233
Ensembl chr  X:105,239,620...105,289,808
JBrowse link
G Dsc1 desmocollin 1 decreases expression ISO Isotretinoin results in decreased expression of DSC1 mRNA CTD PMID:15982314 NCBI chr18:11,877,918...11,906,828
Ensembl chr18:11,877,561...11,906,827
JBrowse link
G Dsc2 desmocollin 2 decreases expression ISO Isotretinoin results in decreased expression of DSC2 mRNA CTD PMID:20436886 NCBI chr18:11,826,705...11,858,801
Ensembl chr18:11,826,706...11,858,754
JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO Isotretinoin results in increased expression of DUSP10 mRNA CTD PMID:15982314 NCBI chr13:104,284,660...104,321,455
Ensembl chr13:104,284,660...104,321,455
JBrowse link
G Dusp11 dual specificity phosphatase 11 decreases expression ISO Isotretinoin results in decreased expression of DUSP11 mRNA CTD PMID:15982314 NCBI chr 4:117,617,640...117,631,674
Ensembl chr 4:117,617,533...117,631,716
JBrowse link
G Dusp4 dual specificity phosphatase 4 decreases expression ISO Isotretinoin results in decreased expression of DUSP4 mRNA CTD PMID:20436886 NCBI chr16:61,080,767...61,090,973
Ensembl chr16:61,078,175...61,091,169
JBrowse link
G E2f8 E2F transcription factor 8 decreases expression ISO Isotretinoin results in decreased expression of E2F8 mRNA CTD PMID:20436886 NCBI chr 1:104,185,436...104,203,683
Ensembl chr 1:104,187,100...104,202,591
JBrowse link
G Ebp EBP, cholestenol delta-isomerase decreases expression ISO Isotretinoin results in decreased expression of EBP mRNA CTD PMID:20436886 NCBI chr  X:15,049,394...15,055,782
Ensembl chr  X:15,049,462...15,055,781
JBrowse link
G Ech1 enoyl-CoA hydratase 1 decreases expression ISO Isotretinoin results in decreased expression of ECH1 mRNA CTD PMID:20436886 NCBI chr 1:87,009,798...87,015,996
Ensembl chr 1:87,009,730...87,016,005
JBrowse link
G Echdc1 ethylmalonyl-CoA decarboxylase 1 decreases expression ISO Isotretinoin results in decreased expression of ECHDC1 mRNA CTD PMID:20436886 NCBI chr 1:30,874,410...30,921,117
Ensembl chr 1:30,874,418...30,917,882
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 decreases expression ISO Isotretinoin results in decreased expression of ECI1 mRNA CTD PMID:20436886 NCBI chr10:13,797,573...13,810,918
Ensembl chr10:13,797,562...13,810,913
JBrowse link
G Efemp2 EGF containing fibulin extracellular matrix protein 2 increases expression ISO Isotretinoin results in increased expression of EFEMP2 mRNA CTD PMID:20436886 NCBI chr 1:220,853,695...220,861,420
Ensembl chr 1:220,854,403...220,861,420
JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO Isotretinoin results in decreased expression of EGFR mRNA CTD PMID:15982314 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egr3 early growth response 3 decreases expression ISO Isotretinoin results in decreased expression of EGR3 mRNA CTD PMID:20436886 NCBI chr15:51,756,683...51,762,080
Ensembl chr15:51,756,736...51,760,722
JBrowse link
G Ei24 EI24, autophagy associated transmembrane protein decreases expression ISO Isotretinoin results in decreased expression of EI24 mRNA CTD PMID:20436886 NCBI chr 8:39,254,883...39,271,238
Ensembl chr 8:39,254,889...39,266,959
JBrowse link
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma decreases expression ISO Isotretinoin results in decreased expression of EIF2B3 mRNA CTD PMID:20436886 NCBI chr 5:135,882,946...135,949,276
Ensembl chr 5:135,882,967...135,949,818
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E decreases expression ISO Isotretinoin results in decreased expression of EIF4E mRNA CTD PMID:20436886 NCBI chr 2:243,819,616...243,853,987
Ensembl chr 2:243,820,661...243,852,631
JBrowse link
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 decreases expression ISO Isotretinoin results in decreased expression of EIF4EBP2 mRNA CTD PMID:15982314 NCBI chr20:31,055,292...31,072,469
Ensembl chr20:31,055,789...31,072,469
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 decreases expression ISO Isotretinoin results in decreased expression of ELL2 mRNA CTD PMID:20436886 NCBI chr 2:2,456,189...2,525,590
Ensembl chr 2:2,456,735...2,524,237
JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 decreases expression ISO Isotretinoin results in decreased expression of ELOVL1 mRNA CTD PMID:20436886 NCBI chr 5:137,255,868...137,260,486
Ensembl chr 5:137,255,908...137,260,483
JBrowse link
G Elovl4 ELOVL fatty acid elongase 4 decreases expression ISO Isotretinoin results in decreased expression of ELOVL4 mRNA CTD PMID:20436886 NCBI chr 8:91,310,690...91,338,625
Ensembl chr 8:91,310,630...91,338,843
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 decreases expression ISO Isotretinoin results in decreased expression of ELOVL5 mRNA CTD PMID:20436886 NCBI chr 8:85,220,941...85,287,449
Ensembl chr 8:85,259,982...85,285,983
JBrowse link
G Emp1 epithelial membrane protein 1 increases expression ISO Isotretinoin results in increased expression of EMP1 mRNA CTD PMID:15982314 NCBI chr 4:169,161,076...169,181,967
Ensembl chr 4:169,147,243...169,181,966
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit decreases expression ISO Isotretinoin results in decreased expression of ERCC1 mRNA CTD PMID:20436886 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Erg28 ergosterol biosynthesis 28 homolog decreases expression ISO Isotretinoin results in decreased expression of ERG28 mRNA CTD PMID:20436886 NCBI chr 6:109,683,252...109,692,218
Ensembl chr 6:109,683,253...109,692,218
JBrowse link
G Esr2 estrogen receptor 2 decreases expression EXP Isotretinoin results in decreased expression of ESR2 mRNA CTD PMID:19041696 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Etfdh electron transfer flavoprotein dehydrogenase decreases expression ISO Isotretinoin results in decreased expression of ETFDH mRNA CTD PMID:20436886 NCBI chr 2:178,367,547...178,389,641
Ensembl chr 2:178,367,549...178,389,608
JBrowse link
G Etnk1 ethanolamine kinase 1 decreases expression ISO Isotretinoin results in decreased expression of ETNK1 mRNA CTD PMID:20436886 NCBI chr 4:177,402,904...177,447,047
Ensembl chr 4:177,402,904...177,447,028
JBrowse link
G Exoc7 exocyst complex component 7 decreases expression ISO Isotretinoin results in decreased expression of EXO70 mRNA CTD PMID:20436886 NCBI chr10:105,242,152...105,259,795
Ensembl chr10:105,242,152...105,259,795
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 decreases expression ISO Isotretinoin results in decreased expression of EYA1 mRNA CTD PMID:31711903 NCBI chr 5:4,275,728...4,495,525
Ensembl chr 5:4,373,626...4,513,142
JBrowse link
G Fa2h fatty acid 2-hydroxylase decreases expression ISO Isotretinoin results in decreased expression of FA2H mRNA CTD PMID:20436886 NCBI chr19:43,545,380...43,596,788
Ensembl chr19:43,545,378...43,596,801
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression EXP Isotretinoin results in increased expression of FABP4 mRNA CTD PMID:19212007 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression ISO Isotretinoin results in decreased expression of FABP5 mRNA CTD PMID:15982314 NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378
JBrowse link
G Fabp6 fatty acid binding protein 6 decreases expression ISO Isotretinoin results in decreased expression of FABP6 mRNA CTD PMID:20436886 NCBI chr10:29,191,621...29,196,593
Ensembl chr10:29,191,623...29,196,563
JBrowse link
G Fabp7 fatty acid binding protein 7 decreases expression ISO Isotretinoin results in decreased expression of FABP7 mRNA CTD PMID:20436886 NCBI chr20:40,769,624...40,773,156
Ensembl chr20:40,769,586...40,773,349
JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression ISO Isotretinoin results in decreased expression of FADS1 mRNA CTD PMID:20436886 NCBI chr 1:226,234,034...226,249,118
Ensembl chr 1:226,234,074...226,249,138
JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression ISO Isotretinoin results in decreased expression of FADS2 mRNA CTD PMID:20436886 NCBI chr 1:225,906,582...226,152,568
Ensembl chr 1:226,114,413...226,152,524
JBrowse link
G Fam149a family with sequence similarity 149, member A increases expression ISO Isotretinoin results in increased expression of FAM149A mRNA CTD PMID:20436886 NCBI chr16:50,049,816...50,105,962
Ensembl chr16:50,049,828...50,107,856
JBrowse link
G Fam3c FAM3 metabolism regulating signaling molecule C increases expression
decreases expression
ISO Isotretinoin results in increased expression of FAM3C mRNA
Isotretinoin results in decreased expression of FAM3C mRNA
CTD PMID:15982314 PMID:20436886 NCBI chr 4:49,388,962...49,439,892
Ensembl chr 4:49,387,989...49,439,867
JBrowse link
G Far2 fatty acyl CoA reductase 2 decreases expression ISO Isotretinoin results in decreased expression of FAR2 mRNA CTD PMID:20436886 NCBI chr 4:182,446,400...182,563,485
Ensembl chr 4:182,483,194...182,565,436
JBrowse link
G Fasn fatty acid synthase decreases expression ISO Isotretinoin results in decreased expression of FASN mRNA CTD PMID:15982314 PMID:20436886 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fastk Fas-activated serine/threonine kinase decreases expression ISO Isotretinoin results in decreased expression of FASTK mRNA CTD PMID:15982314 NCBI chr 4:7,260,521...7,264,590
Ensembl chr 4:7,260,575...7,264,589
JBrowse link
G Fbln1 fibulin 1 increases expression ISO Isotretinoin results in increased expression of FBLN1 mRNA CTD PMID:20436886 NCBI chr 7:126,096,793...126,176,468
Ensembl chr 7:126,096,793...126,176,468
JBrowse link
G Fbp1 fructose-bisphosphatase 1 decreases expression ISO Isotretinoin results in decreased expression of FBP1 mRNA CTD PMID:20436886 NCBI chr17:396,175...417,480
Ensembl chr17:396,180...417,480
JBrowse link
G Fbp2 fructose-bisphosphatase 2 decreases expression ISO Isotretinoin results in decreased expression of FBP2 mRNA CTD PMID:20436886 NCBI chr17:372,554...389,918
Ensembl chr17:372,551...389,967
JBrowse link
G Fbxl7 F-box and leucine-rich repeat protein 7 increases expression ISO Isotretinoin results in increased expression of FBXL7 mRNA CTD PMID:20436886 NCBI chr 2:79,067,907...79,439,987
Ensembl chr 2:79,067,915...79,078,258
JBrowse link
G Fbxo9 f-box protein 9 decreases expression ISO Isotretinoin results in decreased expression of FBXO9 mRNA CTD PMID:20436886 NCBI chr 8:85,388,331...85,413,896
Ensembl chr 8:85,388,333...85,413,484
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression ISO Isotretinoin results in decreased expression of FDFT1 mRNA CTD PMID:20436886 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression ISO Isotretinoin results in decreased expression of FDPS mRNA CTD PMID:20436886 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Fez2 fasciculation and elongation protein zeta 2 increases expression ISO Isotretinoin results in increased expression of FEZ2 mRNA CTD PMID:20436886 NCBI chr 6:963,903...1,003,955
Ensembl chr 6:963,907...1,004,001
JBrowse link
G Fgf1 fibroblast growth factor 1 decreases expression ISO Isotretinoin results in decreased expression of FGF1 mRNA CTD PMID:15982314 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 increases expression ISO Isotretinoin results in increased expression of FGFR1 mRNA CTD PMID:20436886 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 increases expression ISO Isotretinoin results in increased expression of FGFR3 mRNA CTD PMID:20436886 NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706
JBrowse link
G Fh fumarate hydratase decreases expression ISO Isotretinoin results in decreased expression of FH mRNA CTD PMID:20436886 NCBI chr13:93,651,486...93,677,371
Ensembl chr13:93,651,484...93,677,377
JBrowse link
G Fkbp10 FKBP prolyl isomerase 10 increases expression ISO Isotretinoin results in increased expression of FKBP10 mRNA CTD PMID:20436886 NCBI chr10:88,326,337...88,338,199
Ensembl chr10:88,326,080...88,338,207
JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 decreases expression ISO Isotretinoin results in decreased expression of FKBP8 mRNA CTD PMID:15982314 NCBI chr16:20,645,956...20,652,890
Ensembl chr16:20,645,957...20,652,889
JBrowse link
G Flg filaggrin decreases expression ISO Isotretinoin results in decreased expression of FLG mRNA CTD PMID:15982314 NCBI chr 2:193,565,401...193,574,297 JBrowse link
G Flna filamin A increases expression ISO Isotretinoin results in increased expression of FLNA mRNA CTD PMID:20436886 NCBI chr  X:156,460,785...156,487,245
Ensembl chr  X:156,463,953...156,487,245
JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand increases expression ISO Isotretinoin results in increased expression of FLT3LG mRNA CTD PMID:20436886 NCBI chr 1:101,126,006...101,131,413
Ensembl chr 1:101,124,479...101,131,413
JBrowse link
G Fn1 fibronectin 1 increases expression ISO Isotretinoin results in increased expression of FN1 mRNA CTD PMID:20436886 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Isotretinoin affects the localization of and results in decreased activity of FOS protein CTD PMID:18652567 PMID:19066126 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Isotretinoin results in decreased expression of FOSB mRNA CTD PMID:20436886 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710
JBrowse link
G Foxc2 forkhead box C2 decreases expression ISO Isotretinoin results in decreased expression of FOXC2 mRNA CTD PMID:31711903 NCBI chr19:53,044,379...53,047,081
Ensembl chr19:53,044,379...53,047,081
JBrowse link
G Foxd1 forkhead box D1 increases expression ISO Isotretinoin results in increased expression of FOXD1 mRNA CTD PMID:20436886 NCBI chr 2:28,460,068...28,462,488
Ensembl chr 2:28,460,068...28,462,488
JBrowse link
G Fut8 fucosyltransferase 8 increases expression ISO Isotretinoin results in increased expression of FUT8 mRNA CTD PMID:20436886 NCBI chr 6:100,305,957...100,537,208
Ensembl chr 6:100,337,226...100,537,224
JBrowse link
G Fyb1 FYN binding protein 1 increases expression ISO Isotretinoin results in increased expression of FYB1 mRNA CTD PMID:18769122 NCBI chr 2:55,834,904...55,983,805
Ensembl chr 2:55,835,151...55,983,804
JBrowse link
G Fzd5 frizzled class receptor 5 decreases expression ISO Isotretinoin results in decreased expression of FZD5 mRNA CTD PMID:20436886 NCBI chr 9:71,443,784...71,445,541
Ensembl chr 9:71,443,588...71,445,739
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases expression
multiple interactions
increases expression
ISO Isotretinoin results in decreased expression of G6PD mRNA
Isotretinoin inhibits the reaction [Benzoyl Peroxide results in decreased activity of G6PD protein]
Isotretinoin results in increased expression of G6PD mRNA
CTD PMID:15225900 PMID:15982314 PMID:20436886 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 decreases expression ISO Isotretinoin results in decreased expression of GABRA4 mRNA CTD PMID:20436886 NCBI chr14:39,154,072...39,230,994
Ensembl chr14:39,154,529...39,231,695
JBrowse link
G Gal galanin and GMAP prepropeptide decreases expression ISO Isotretinoin results in decreased expression of GAL mRNA CTD PMID:20436886 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
JBrowse link
G Gata3 GATA binding protein 3 multiple interactions ISO [vorinostat co-treated with Isotretinoin] results in increased expression of GATA3 mRNA CTD PMID:18769122 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Gatd3a glutamine amidotransferase like class 1 domain containing 3A decreases expression ISO Isotretinoin results in decreased expression of GATD3A mRNA CTD PMID:20436886 NCBI chr20:11,244,353...11,252,450
Ensembl chr20:11,244,353...11,252,449
JBrowse link
G Gba glucosylceramidase beta decreases expression ISO Isotretinoin results in decreased expression of GBA mRNA CTD PMID:15982314 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 decreases expression ISO Isotretinoin results in decreased expression of GBE1 mRNA CTD PMID:20436886 NCBI chr11:7,210,169...7,485,895
Ensembl chr11:7,210,209...7,485,890
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit decreases expression ISO Isotretinoin results in decreased expression of GCLM mRNA CTD PMID:20436886 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO Isotretinoin results in increased expression of GCNT3 mRNA CTD PMID:18769122 NCBI chr 8:76,449,078...76,459,431
Ensembl chr 8:76,449,081...76,452,554
JBrowse link
G Gcsh glycine cleavage system protein H decreases expression ISO Isotretinoin results in decreased expression of GCSH mRNA CTD PMID:20436886 NCBI chr19:49,522,054...49,532,811
Ensembl chr19:49,522,054...49,532,811
JBrowse link
G Gdap1l1 ganglioside-induced differentiation-associated protein 1-like 1 decreases expression ISO Isotretinoin results in decreased expression of GDAP1L1 mRNA CTD PMID:20436886 NCBI chr 3:159,823,791...159,843,260
Ensembl chr 3:159,823,878...159,842,278
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Isotretinoin results in increased expression of GDF15 mRNA CTD PMID:15982314 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gdf2 growth differentiation factor 2 increases expression ISO Isotretinoin results in increased expression of GDF2 mRNA CTD PMID:15982314 NCBI chr16:10,267,510...10,293,545
Ensembl chr16:10,267,482...10,273,239
JBrowse link
G Ggcx gamma-glutamyl carboxylase decreases expression ISO Isotretinoin results in decreased expression of GGCX mRNA CTD PMID:20436886 NCBI chr 4:100,277,345...100,293,097
Ensembl chr 4:100,277,391...100,293,250
JBrowse link
G Ggps1 geranylgeranyl diphosphate synthase 1 decreases expression ISO Isotretinoin results in decreased expression of GGPS1 mRNA CTD PMID:20436886 NCBI chr17:53,956,185...53,971,039
Ensembl chr17:53,956,203...53,971,443
JBrowse link
G Ghitm growth hormone inducible transmembrane protein decreases expression ISO Isotretinoin results in decreased expression of GHITM mRNA CTD PMID:20436886 NCBI chr16:14,370,269...14,382,647
Ensembl chr16:14,371,531...14,382,641
JBrowse link
G Gins1 GINS complex subunit 1 decreases expression ISO Isotretinoin results in decreased expression of GINS1 mRNA CTD PMID:20436886 NCBI chr 3:146,695,366...146,716,787
Ensembl chr 3:146,695,344...146,716,816
JBrowse link
G Gk glycerol kinase decreases expression ISO Isotretinoin results in decreased expression of GK mRNA CTD PMID:20436886 NCBI chr  X:54,227,291...54,303,897
Ensembl chr  X:54,227,397...54,303,864
JBrowse link
G Gldc glycine decarboxylase decreases expression ISO Isotretinoin results in decreased expression of GLDC mRNA CTD PMID:20436886 NCBI chr 1:248,295,140...248,377,122
Ensembl chr 1:248,297,331...248,377,093
JBrowse link
G Glrx2 glutaredoxin 2 decreases expression ISO Isotretinoin results in decreased expression of GLRX2 mRNA CTD PMID:20436886 NCBI chr13:60,529,057...60,552,115
Ensembl chr13:60,529,932...60,537,916
JBrowse link
G Glrx5 glutaredoxin 5 decreases expression ISO Isotretinoin results in decreased expression of GLRX5 mRNA CTD PMID:20436886 NCBI chr 6:128,750,503...128,760,880
Ensembl chr 6:128,750,795...128,760,880
JBrowse link
G Glul glutamate-ammonia ligase increases expression ISO Isotretinoin results in increased expression of GLUL mRNA CTD PMID:15982314 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Gng4 G protein subunit gamma 4 decreases expression ISO Isotretinoin results in decreased expression of GNG4 mRNA CTD PMID:20436886 NCBI chr17:90,266,571...90,316,278
Ensembl chr17:90,266,794...90,315,492
JBrowse link
G Gnpat glyceronephosphate O-acyltransferase decreases expression ISO Isotretinoin results in decreased expression of GNPAT mRNA CTD PMID:20436886 NCBI chr19:57,614,813...57,640,524
Ensembl chr19:57,614,628...57,640,726
JBrowse link
G Gpr143 G protein-coupled receptor 143 decreases expression ISO Isotretinoin results in decreased expression of GPR143 mRNA CTD PMID:20436886 NCBI chr  X:23,668,363...23,693,162
Ensembl chr  X:23,668,363...23,693,162
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO Isotretinoin results in increased expression of GPX2 mRNA CTD PMID:15623509 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gpx3 glutathione peroxidase 3 decreases expression ISO Isotretinoin results in decreased expression of GPX3 mRNA CTD PMID:20436886 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Grb7 growth factor receptor bound protein 7 decreases expression ISO Isotretinoin results in decreased expression of GRB7 mRNA CTD PMID:15982314 NCBI chr10:86,393,186...86,408,893
Ensembl chr10:86,399,827...86,409,348
JBrowse link
G Grpel1 GrpE-like 1, mitochondrial decreases expression ISO Isotretinoin results in decreased expression of GRPEL1 mRNA CTD PMID:20436886 NCBI chr14:79,458,951...79,464,782
Ensembl chr14:79,458,963...79,464,770
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO Isotretinoin inhibits the reaction [Benzoyl Peroxide results in decreased activity of GSR protein] CTD PMID:15225900 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases expression ISO Isotretinoin results in decreased expression of GSTM1 mRNA CTD PMID:15982314 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
affects metabolic processing
ISO Ethacrynic Acid inhibits the reaction [GSTP1 protein affects the metabolism of Isotretinoin]; S-decylglutathione inhibits the reaction [GSTP1 protein affects the metabolism of Isotretinoin] CTD PMID:9806904 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 decreases expression ISO Isotretinoin results in decreased expression of GSTZ1 mRNA CTD PMID:20436886 NCBI chr 6:111,176,798...111,187,246
Ensembl chr 6:111,176,798...111,187,244
JBrowse link
G H1f2 H1.2 linker histone, cluster member decreases expression ISO Isotretinoin results in decreased expression of H1-2 mRNA CTD PMID:20436886 NCBI chr17:43,638,938...43,640,445
Ensembl chr17:43,639,749...43,640,387
JBrowse link
G H2ax H2A.X variant histone decreases expression ISO Isotretinoin results in decreased expression of H2AX mRNA CTD PMID:20436886 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G H2bc12 H2B clustered histone 12 decreases expression ISO Isotretinoin results in decreased expression of H2BC12 mRNA CTD PMID:20436886 NCBI chr17:44,527,421...44,527,801
Ensembl chr17:44,527,421...44,527,801
JBrowse link
G H2bc9 H2B clustered histone 9 decreases expression ISO Isotretinoin results in decreased expression of H2BC9 mRNA CTD PMID:20436886 NCBI chr17:44,519,815...44,520,269
Ensembl chr17:44,519,860...44,520,240
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase decreases expression ISO Isotretinoin results in decreased expression of HADH mRNA CTD PMID:20436886 NCBI chr 2:236,353,445...236,395,067
Ensembl chr 2:236,353,445...236,395,067
JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression ISO Isotretinoin results in decreased expression of HAO2 mRNA CTD PMID:20436886 NCBI chr 2:200,785,492...200,808,868
Ensembl chr 2:200,778,122...200,808,857
JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Isotretinoin results in increased expression of HBEGF mRNA CTD PMID:15982314 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hcls1 hematopoietic cell specific Lyn substrate 1 increases expression ISO Isotretinoin results in increased expression of HCLS1 mRNA CTD PMID:20436886 NCBI chr11:66,736,966...66,759,402
Ensembl chr11:66,736,966...66,759,402
JBrowse link
G Hcn3 hyperpolarization-activated cyclic nucleotide-gated potassium channel 3 decreases expression ISO Isotretinoin results in decreased expression of HCN3 mRNA CTD PMID:20436886 NCBI chr 2:188,458,851...188,471,916
Ensembl chr 2:188,454,853...188,471,988
JBrowse link
G Hgd homogentisate 1, 2-dioxygenase decreases expression ISO Isotretinoin results in decreased expression of HGD mRNA CTD PMID:20436886 NCBI chr11:65,983,221...66,034,555
Ensembl chr11:65,983,221...66,034,573
JBrowse link
G Hgf hepatocyte growth factor decreases expression
decreases secretion
ISO Isotretinoin results in decreased expression of HGF mRNA
Isotretinoin results in decreased secretion of HGF protein
CTD PMID:11223164 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase decreases expression ISO Isotretinoin results in decreased expression of HIBCH mRNA CTD PMID:20436886 NCBI chr 9:53,446,185...53,526,727
Ensembl chr 9:53,446,194...53,526,728
JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated decreases expression ISO Isotretinoin results in decreased expression of HILPDA mRNA CTD PMID:20436886 NCBI chr 4:56,547,600...56,550,584
Ensembl chr 4:56,549,739...56,549,993
JBrowse link
G Hip1 huntingtin interacting protein 1 increases expression ISO Isotretinoin results in increased expression of HIP1 mRNA CTD PMID:20436886 NCBI chr12:24,180,795...24,315,373
Ensembl chr12:24,180,937...24,315,373
JBrowse link
G Hist1h2af histone cluster 1 H2A family member F decreases expression ISO Isotretinoin results in decreased expression of H2AC8 mRNA CTD PMID:20436886 NCBI chr17:43,627,237...43,627,629
Ensembl chr17:43,627,237...43,627,629
JBrowse link
G Hist1h2ah histone cluster 1 H2A family member H decreases expression ISO Isotretinoin results in decreased expression of H2AC11 mRNA CTD PMID:20436886 NCBI chr17:43,632,354...43,632,851
Ensembl chr17:44,747,796...44,748,188
Ensembl chr17:44,747,796...44,748,188
JBrowse link
G Hist1h2bd histone cluster 1 H2B family member D decreases expression ISO Isotretinoin results in decreased expression of H2BC5 mRNA CTD PMID:20436886 NCBI chr17:44,833,924...44,834,305
Ensembl chr17:44,833,924...44,834,305
JBrowse link
G Hlcs holocarboxylase synthetase decreases expression ISO Isotretinoin results in decreased expression of HLCS mRNA CTD PMID:20436886 NCBI chr11:34,357,372...34,537,798
Ensembl chr11:34,352,287...34,526,931
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO Isotretinoin results in decreased expression of HMGCR mRNA CTD PMID:20436886 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO Isotretinoin results in decreased expression of HMGCS1 mRNA CTD PMID:20436886 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression ISO Isotretinoin results in decreased expression of HSD11B1 mRNA CTD PMID:15982314 PMID:20436886 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 decreases expression ISO Isotretinoin results in decreased expression of HSD17B12 mRNA CTD PMID:20436886 NCBI chr 3:82,924,699...83,048,465
Ensembl chr 3:82,924,687...83,048,435
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 decreases expression ISO Isotretinoin results in decreased expression of HSD17B7 mRNA CTD PMID:20436886 NCBI chr13:88,288,116...88,308,019
Ensembl chr13:88,288,046...88,307,988
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO Isotretinoin results in decreased expression of HSD3B1 mRNA CTD PMID:20436886
G Hsp90b1 heat shock protein 90 beta family member 1 decreases expression ISO Isotretinoin results in decreased expression of HSP90B1 mRNA CTD PMID:20436886 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 decreases expression ISO Isotretinoin results in decreased expression of HSPA9 mRNA CTD PMID:20436886 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression ISO Isotretinoin results in decreased expression of HSPD1 mRNA CTD PMID:20436886 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Htra1 HtrA serine peptidase 1 increases expression ISO Isotretinoin results in increased expression of HTRA1 mRNA CTD PMID:20436886 NCBI chr 1:201,499,067...201,548,508
Ensembl chr 1:201,499,028...201,548,513
JBrowse link
G Hus1 HUS1 checkpoint clamp component decreases expression ISO Isotretinoin results in decreased expression of HUS1 mRNA CTD PMID:20436886 NCBI chr14:89,194,086...89,208,825
Ensembl chr14:89,194,092...89,208,825
JBrowse link
G Icam2 intercellular adhesion molecule 2 increases expression ISO Isotretinoin results in increased expression of ICAM2 mRNA CTD PMID:20436886 NCBI chr10:94,569,889...94,581,218
Ensembl chr10:94,569,890...94,576,512
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 decreases expression ISO Isotretinoin results in decreased expression of IDH1 mRNA CTD PMID:20436886 NCBI chr 9:71,882,108...71,911,645
Ensembl chr 9:71,882,105...71,900,044
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO Isotretinoin results in decreased expression of IDI1 mRNA CTD PMID:20436886 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036
JBrowse link
G Ier3 immediate early response 3 decreases expression ISO Isotretinoin results in decreased expression of IER3 mRNA CTD PMID:20436886 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Ifi35 interferon-induced protein 35 increases expression ISO Isotretinoin results in increased expression of IFI35 mRNA CTD PMID:20436886 NCBI chr10:89,358,376...89,366,628
Ensembl chr10:89,358,376...89,366,626
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 decreases expression ISO Isotretinoin results in decreased expression of IFRD1 mRNA CTD PMID:20436886 NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420
JBrowse link
G Ift20 intraflagellar transport 20 decreases expression ISO Isotretinoin results in decreased expression of IFT20 mRNA CTD PMID:20436886 NCBI chr10:65,805,808...65,811,353
Ensembl chr10:65,805,860...65,811,351
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO Isotretinoin results in increased expression of IGF1 mRNA CTD PMID:15982314 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression ISO Isotretinoin results in increased expression of IGFBP3 mRNA CTD PMID:18769122 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 increases expression ISO Isotretinoin results in increased expression of IGFBP4 mRNA CTD PMID:20436886 NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 increases expression ISO Isotretinoin results in increased expression of IGFBP5 mRNA CTD PMID:20436886 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Il10 interleukin 10 decreases expression
decreases secretion
EXP Isotretinoin results in decreased expression of IL10 mRNA
Isotretinoin results in decreased secretion of IL10 protein
CTD PMID:15972972 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il10ra interleukin 10 receptor subunit alpha decreases expression ISO Isotretinoin results in decreased expression of IL10RA mRNA CTD PMID:15982314 NCBI chr 8:49,558,062...49,573,891
Ensembl chr 8:49,560,035...49,573,742
JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 decreases expression ISO Isotretinoin results in decreased expression of IL13RA1 mRNA CTD PMID:20436886 NCBI chr  X:122,724,081...122,783,801
Ensembl chr  X:122,724,129...122,781,479
JBrowse link
G Il1a interleukin 1 alpha decreases secretion EXP Isotretinoin results in decreased secretion of IL1A protein CTD PMID:15972972 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta decreases expression
decreases secretion
multiple interactions
increases expression
ISO
EXP
Isotretinoin results in decreased expression of IL1B mRNA
Isotretinoin results in decreased secretion of IL1B protein
[vorinostat co-treated with Isotretinoin] results in increased expression of IL1B mRNA
Isotretinoin results in increased expression of IL1B mRNA
CTD PMID:15972972 PMID:15982314 PMID:18769122 PMID:20436886 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r2 interleukin 1 receptor type 2 decreases expression ISO Isotretinoin results in decreased expression of IL1R2 mRNA CTD PMID:20436886 NCBI chr 9:46,840,646...46,881,241
Ensembl chr 9:46,840,992...46,881,264
JBrowse link
G Il2 interleukin 2 decreases secretion EXP Isotretinoin results in decreased secretion of IL2 protein CTD PMID:15972972 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il24 interleukin 24 decreases expression ISO Isotretinoin results in decreased expression of IL24 mRNA CTD PMID:15982314 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
JBrowse link
G Il4 interleukin 4 decreases secretion EXP Isotretinoin results in decreased secretion of IL4 protein CTD PMID:15972972 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 decreases expression
decreases secretion
ISO
EXP
Isotretinoin results in decreased expression of IL6 mRNA
Isotretinoin results in decreased secretion of IL6 protein
CTD PMID:15972972 PMID:17033190 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B decreases expression ISO Isotretinoin results in decreased expression of INPP4B mRNA CTD PMID:20436886 NCBI chr19:29,592,889...30,341,528
Ensembl chr19:29,597,905...29,968,424
JBrowse link
G Insig1 insulin induced gene 1 decreases expression ISO Isotretinoin results in decreased expression of INSIG1 mRNA CTD PMID:20436886 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO Isotretinoin promotes the reaction [Dacarbazine results in increased expression of IRF1 mRNA] CTD PMID:17973783 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Isca1 iron-sulfur cluster assembly 1 decreases expression ISO Isotretinoin results in decreased expression of ISCA1 mRNA CTD PMID:20436886 NCBI chr17:5,281,727...5,294,386
Ensembl chr17:5,281,727...5,294,384
JBrowse link
G Islr immunoglobulin superfamily containing leucine-rich repeat increases expression ISO Isotretinoin results in increased expression of ISLR mRNA CTD PMID:20436886 NCBI chr 8:62,946,732...62,949,675
Ensembl chr 8:62,946,732...62,948,720
JBrowse link
G Isoc1 isochorismatase domain containing 1 decreases expression ISO Isotretinoin results in decreased expression of ISOC1 mRNA CTD PMID:20436886 NCBI chr18:53,727,203...53,747,612
Ensembl chr18:53,727,209...53,745,200
JBrowse link
G Itga4 integrin subunit alpha 4 increases expression ISO Isotretinoin results in increased expression of ITGA4 mRNA CTD PMID:15982314 NCBI chr 3:66,178,745...66,265,547
Ensembl chr 3:66,193,059...66,263,960
JBrowse link
G Itgav integrin subunit alpha V increases expression ISO Isotretinoin results in increased expression of ITGAV mRNA CTD PMID:20436886 NCBI chr 3:71,113,269...71,205,958
Ensembl chr 3:71,114,100...71,202,411
JBrowse link
G Itgb2 integrin subunit beta 2 increases expression ISO Isotretinoin results in increased expression of ITGB2 mRNA CTD PMID:20436886 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Jak1 Janus kinase 1 increases expression ISO Isotretinoin results in increased expression of JAK1 mRNA CTD PMID:20436886 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Kank2 KN motif and ankyrin repeat domains 2 increases expression ISO Isotretinoin results in increased expression of KANK2 mRNA CTD PMID:20436886 NCBI chr 8:22,792,000...22,821,459
Ensembl chr 8:22,791,995...22,821,397
JBrowse link
G Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 decreases expression ISO Isotretinoin results in decreased expression of KCNJ15 mRNA CTD PMID:20436886 NCBI chr11:35,545,185...35,588,517
Ensembl chr11:35,568,182...35,585,390
JBrowse link
G Kcnk1 potassium two pore domain channel subfamily K member 1 decreases expression ISO Isotretinoin results in decreased expression of KCNK1 mRNA CTD PMID:20436886 NCBI chr19:58,823,836...58,862,926
Ensembl chr19:58,823,814...58,862,926
JBrowse link
G Kctd12 potassium channel tetramerization domain containing 12 increases expression ISO Isotretinoin results in increased expression of KCTD12 mRNA CTD PMID:20436886 NCBI chr15:87,384,632...87,390,627 JBrowse link
G Klhdc4 kelch domain containing 4 decreases expression ISO Isotretinoin results in decreased expression of KLHDC4 mRNA CTD PMID:20436886 NCBI chr19:54,651,911...54,652,381
Ensembl chr19:54,651,911...54,652,381
JBrowse link
G Kras KRAS proto-oncogene, GTPase decreases expression ISO Isotretinoin results in decreased expression of KRAS mRNA CTD PMID:20436886 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Krt1 keratin 1 decreases expression ISO Isotretinoin results in decreased expression of KRT1 mRNA CTD PMID:15982314 NCBI chr 7:143,448,318...143,453,544
Ensembl chr 7:143,448,318...143,453,544
JBrowse link
G Krt10 keratin 10 decreases expression ISO Isotretinoin results in decreased expression of KRT10 mRNA CTD PMID:15982314 NCBI chr10:87,296,445...87,301,307
Ensembl chr10:87,296,451...87,300,736
JBrowse link
G Krt14 keratin 14 decreases expression ISO Isotretinoin results in decreased expression of KRT14 mRNA; Isotretinoin results in decreased expression of KRT14 protein CTD PMID:15982314 NCBI chr10:88,118,029...88,122,233
Ensembl chr10:88,055,823...88,122,233
JBrowse link
G Krt15 keratin 15 increases expression ISO Isotretinoin results in increased expression of KRT15 mRNA CTD PMID:15982314 NCBI chr10:88,046,803...88,050,622
Ensembl chr10:88,046,803...88,050,622
JBrowse link
G Krt16 keratin 16 decreases expression ISO Isotretinoin results in decreased expression of KRT16 mRNA CTD PMID:20436886 NCBI chr10:88,149,210...88,152,167
Ensembl chr10:88,149,345...88,152,064
JBrowse link
G Krt17 keratin 17 decreases expression ISO Isotretinoin results in decreased expression of KRT17 mRNA; Isotretinoin results in decreased expression of KRT17 protein CTD PMID:15982314 PMID:18769122 NCBI chr10:88,158,993...88,163,712
Ensembl chr10:88,118,001...88,163,723
JBrowse link
G Krt19 keratin 19 increases expression ISO Isotretinoin results in increased expression of KRT19 mRNA; Isotretinoin results in increased expression of KRT19 protein CTD PMID:15982314 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561
JBrowse link
G Krt5 keratin 5 decreases expression ISO Isotretinoin results in decreased expression of KRT5 mRNA CTD PMID:15982314 NCBI chr 7:143,320,142...143,324,536
Ensembl chr 7:143,316,920...143,453,546
JBrowse link
G Krt7 keratin 7 increases expression ISO Isotretinoin results in increased expression of KRT7 mRNA; Isotretinoin results in increased expression of KRT7 protein CTD PMID:15982314 NCBI chr 7:143,059,731...143,075,907
Ensembl chr 7:143,059,764...143,075,907
JBrowse link
G Krt75 keratin 75 decreases expression ISO Isotretinoin results in decreased expression of KRT75 mRNA CTD PMID:15982314 NCBI chr 7:143,219,012...143,228,237
Ensembl chr 7:143,219,012...143,228,060
JBrowse link
G Lactb2 lactamase, beta 2 decreases expression ISO Isotretinoin results in decreased expression of LACTB2 mRNA CTD PMID:20436886 NCBI chr 5:4,982,348...5,005,111
Ensembl chr 5:4,982,348...5,005,109
JBrowse link
G Lage3 L antigen family, member 3 decreases expression ISO Isotretinoin results in decreased expression of LAGE3 mRNA CTD PMID:20436886 NCBI chr  X:156,355,376...156,356,799
Ensembl chr  X:156,355,376...156,356,799
JBrowse link
G Lama2 laminin subunit alpha 2 decreases expression
increases expression
ISO Isotretinoin results in decreased expression of LAMA2 mRNA
Isotretinoin results in increased expression of LAMA2 mRNA
CTD PMID:15982314 PMID:20436886 NCBI chr 1:18,491,264...19,143,486
Ensembl chr 1:18,491,384...19,143,269
JBrowse link
G Lama3 laminin subunit alpha 3 decreases expression ISO Isotretinoin results in decreased expression of LAMA3 mRNA CTD PMID:15982314 NCBI chr18:3,704,866...3,941,215
Ensembl chr18:3,705,916...3,940,838
JBrowse link
G Lamc1 laminin subunit gamma 1 increases expression ISO Isotretinoin results in increased expression of LAMC1 mRNA CTD PMID:20436886 NCBI chr13:70,656,727...70,783,515
Ensembl chr13:70,658,707...70,783,515
JBrowse link
G Lamc3 laminin subunit gamma 3 increases expression ISO Isotretinoin results in increased expression of LAMC3 mRNA CTD PMID:15982314 NCBI chr 3:9,265,407...9,327,107
Ensembl chr 3:9,267,122...9,326,993
JBrowse link
G Laptm5 lysosomal protein transmembrane 5 increases expression ISO Isotretinoin results in increased expression of LAPTM5 mRNA CTD PMID:20436886 NCBI chr 5:149,015,793...149,069,719
Ensembl chr 5:149,047,681...149,069,719
JBrowse link
G Larp4 La ribonucleoprotein 4 decreases expression ISO Isotretinoin results in decreased expression of LARP4 mRNA CTD PMID:20436886 NCBI chr 7:141,630,229...141,676,242 JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase increases expression ISO Isotretinoin results in increased expression of LCK mRNA CTD PMID:20436886 NCBI chr 5:147,750,976...147,779,627
Ensembl chr 5:147,750,973...147,761,983
JBrowse link
G Lcn2 lipocalin 2 increases expression ISO Isotretinoin results in increased expression of LCN2 mRNA CTD PMID:15982314 PMID:18769122 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Lcp2 lymphocyte cytosolic protein 2 increases expression ISO Isotretinoin results in increased expression of LCP2 mRNA CTD PMID:20436886 NCBI chr10:18,996,523...19,043,289
Ensembl chr10:18,996,523...19,043,286
JBrowse link
G Ldlr low density lipoprotein receptor decreases expression ISO Isotretinoin results in decreased expression of LDLR mRNA CTD PMID:20436886 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lep leptin increases expression EXP Isotretinoin results in increased expression of LEP mRNA CTD PMID:19212007 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lhfpl6 LHFPL tetraspan subfamily member 6 increases expression ISO Isotretinoin results in increased expression of LHFPL6 mRNA CTD PMID:20436886 NCBI chr 2:142,262,236...142,461,980
Ensembl chr 2:142,262,236...142,461,980
JBrowse link
G Limch1 LIM and calponin homology domains 1 increases expression ISO Isotretinoin results in increased expression of LIMCH1 mRNA CTD PMID:20436886 NCBI chr14:42,760,363...43,072,976
Ensembl chr14:42,762,587...43,072,843
JBrowse link
G Lipc lipase C, hepatic type increases expression ISO Isotretinoin results in increased expression of LIPC mRNA CTD PMID:20436886 NCBI chr 8:77,272,582...77,398,485
Ensembl chr 8:77,272,570...77,398,248
JBrowse link
G Lmnb1 lamin B1 increases expression ISO Isotretinoin results in increased expression of LMNB1 protein CTD PMID:15982314 NCBI chr18:51,785,111...51,822,264
Ensembl chr18:51,785,111...51,822,264
JBrowse link
G Lmo2 LIM domain only 2 increases expression ISO Isotretinoin results in increased expression of LMO2 mRNA CTD PMID:20436886 NCBI chr 3:93,909,156...93,931,888
Ensembl chr 3:93,909,156...93,931,871
JBrowse link
G LOC299277 similar to serine (or cysteine) peptidase inhibitor, clade A, member 3B increases expression ISO Isotretinoin results in increased expression of SERPINA3 mRNA CTD PMID:15982314 NCBI chr 6:127,871,895...127,888,287
Ensembl chr 6:127,872,666...127,886,540
JBrowse link
G Loxl2 lysyl oxidase-like 2 increases expression ISO Isotretinoin results in increased expression of LOXL2 mRNA CTD PMID:20436886 NCBI chr15:51,276,022...51,365,238
Ensembl chr15:51,303,909...51,365,234
JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 decreases expression ISO Isotretinoin results in decreased expression of LPCAT3 mRNA CTD PMID:20436886 NCBI chr 4:157,181,722...157,222,997
Ensembl chr 4:157,181,795...157,222,996
JBrowse link
G Lpin1 lipin 1 decreases expression ISO Isotretinoin results in decreased expression of LPIN1 mRNA CTD PMID:20436886 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
G Lrat lecithin retinol acyltransferase increases expression ISO Isotretinoin results in increased expression of LRAT protein CTD PMID:15982314 NCBI chr 2:181,896,304...181,905,366
Ensembl chr 2:181,896,305...181,905,300
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 increases expression ISO Isotretinoin results in increased expression of LTBP1 mRNA CTD PMID:20436886 NCBI chr 6:21,203,502...21,600,441
Ensembl chr 6:21,203,502...21,600,451
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase increases expression ISO Isotretinoin results in increased expression of LYN mRNA CTD PMID:20436886 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648
JBrowse link
G Maff MAF bZIP transcription factor F decreases expression ISO Isotretinoin results in decreased expression of MAFF mRNA CTD PMID:20436886 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Man1a1 mannosidase, alpha, class 1A, member 1 increases expression ISO Isotretinoin results in increased expression of MAN1A1 mRNA CTD PMID:20436886 NCBI chr20:35,257,688...35,450,132
Ensembl chr20:35,257,985...35,450,513
JBrowse link
G Map4 microtubule-associated protein 4 increases expression ISO Isotretinoin results in increased expression of MAP4 mRNA CTD PMID:20436886 NCBI chr 8:118,013,584...118,159,934
Ensembl chr 8:118,013,612...118,159,933
JBrowse link
G Mboat2 membrane bound O-acyltransferase domain containing 2 decreases expression ISO Isotretinoin results in decreased expression of MBOAT2 mRNA CTD PMID:20436886 NCBI chr 6:44,009,872...44,135,501
Ensembl chr 6:44,009,872...44,131,387
JBrowse link
G Mc5r melanocortin 5 receptor decreases expression ISO Isotretinoin results in decreased expression of MC5R mRNA CTD PMID:20436886 NCBI chr18:64,113,659...64,118,700
Ensembl chr18:64,114,933...64,116,524
JBrowse link
G Mcat malonyl-CoA-acyl carrier protein transacylase decreases expression ISO Isotretinoin results in decreased expression of MCAT mRNA CTD PMID:20436886 NCBI chr 7:124,412,762...124,424,966
Ensembl chr 7:124,412,762...124,423,832
JBrowse link
G Mccc1 methylcrotonoyl-CoA carboxylase 1 decreases expression ISO Isotretinoin results in decreased expression of MCCC1 mRNA CTD PMID:20436886 NCBI chr 2:122,550,777...122,690,540
Ensembl chr 2:122,550,775...122,690,617
JBrowse link
G Mccc2 methylcrotonoyl-CoA carboxylase 2 decreases expression ISO Isotretinoin results in decreased expression of MCCC2 mRNA CTD PMID:20436886 NCBI chr 2:30,175,017...30,246,028
Ensembl chr 2:30,175,018...30,246,010
JBrowse link
G Mcfd2 multiple coagulation factor deficiency 2, ER cargo receptor complex subunit decreases expression ISO Isotretinoin results in decreased expression of MCFD2 mRNA CTD PMID:20436886 NCBI chr 6:10,887,303...10,899,221
Ensembl chr 6:10,887,288...10,899,200
JBrowse link
G Mcts1 MCTS1, re-initiation and release factor decreases expression ISO Isotretinoin results in decreased expression of MCTS1 mRNA CTD PMID:20436886 NCBI chr  X:124,894,269...124,906,129
Ensembl chr  X:124,894,466...124,906,162
JBrowse link
G Mcur1 mitochondrial calcium uniporter regulator 1 decreases expression ISO Isotretinoin results in decreased expression of MCUR1 mRNA CTD PMID:20436886 NCBI chr17:24,165,259...24,182,425
Ensembl chr17:24,165,280...24,182,425
JBrowse link
G Mdh1 malate dehydrogenase 1 decreases expression ISO Isotretinoin results in decreased expression of MDH1 mRNA CTD PMID:20436886 NCBI chr14:106,378,349...106,393,642
Ensembl chr14:106,378,942...106,393,670
JBrowse link
G Me1 malic enzyme 1 decreases expression ISO Isotretinoin results in decreased expression of ME1 mRNA CTD PMID:20436886 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Mecr mitochondrial trans-2-enoyl-CoA reductase decreases expression ISO Isotretinoin results in decreased expression of MECR mRNA CTD PMID:20436886 NCBI chr 5:150,001,281...150,027,407
Ensembl chr 5:150,001,281...150,027,049
JBrowse link
G Mef2c myocyte enhancer factor 2C increases expression ISO Isotretinoin results in increased expression of MEF2C mRNA CTD PMID:20436886 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link
G Meox1 mesenchyme homeobox 1 decreases expression ISO Isotretinoin results in decreased expression of MEOX1 mRNA CTD PMID:31711903 NCBI chr10:89,797,011...89,817,009
Ensembl chr10:89,797,038...89,816,491
JBrowse link
G Mesp2 mesoderm posterior bHLH transcription factor 2 decreases expression ISO Isotretinoin results in decreased expression of MESP2 mRNA CTD PMID:31711903 NCBI chr 1:141,550,633...141,553,239
Ensembl chr 1:141,550,633...141,553,230
JBrowse link
G Mfap2 microfibril associated protein 2 decreases expression
increases expression
ISO Isotretinoin results in decreased expression of MFAP2 mRNA
Isotretinoin results in increased expression of MFAP2 mRNA
CTD PMID:15982314 PMID:20436886 NCBI chr 5:159,534,202...159,539,750
Ensembl chr 5:159,534,202...159,539,750
JBrowse link
G Mfap3l microfibril associated protein 3 like decreases expression ISO Isotretinoin results in decreased expression of MFAP3L mRNA CTD PMID:20436886 NCBI chr16:32,734,059...32,777,091
Ensembl chr16:32,738,265...32,753,278
JBrowse link
G Mfap4 microfibril associated protein 4 increases expression ISO Isotretinoin results in increased expression of MFAP4 mRNA CTD PMID:20436886 NCBI chr10:47,765,463...47,768,484
Ensembl chr10:47,765,432...47,768,483
JBrowse link
G Mlana melan-A decreases expression ISO Isotretinoin results in decreased expression of MLANA mRNA CTD PMID:20436886 NCBI chr 1:247,869,756...247,883,558
Ensembl chr 1:247,869,756...247,884,442
JBrowse link
G Mmp10 matrix metallopeptidase 10 decreases expression ISO Isotretinoin results in decreased expression of MMP10 mRNA CTD PMID:15982314 NCBI chr 8:5,734,348...5,742,243
Ensembl chr 8:5,734,348...5,742,243
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions
decreases expression
ISO Isotretinoin inhibits the reaction [Arachidonic Acid results in increased expression of MMP13 mRNA]; Isotretinoin inhibits the reaction [Arachidonic Acid results in increased secretion of MMP13 protein]
Isotretinoin results in decreased expression of MMP13 protein
CTD PMID:16185265 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
ISO Isotretinoin inhibits the reaction [Arachidonic Acid results in increased expression of MMP2 mRNA]; Isotretinoin inhibits the reaction [Arachidonic Acid results in increased secretion of MMP2 protein]
Isotretinoin results in increased expression of MMP2 mRNA
CTD PMID:16185265 PMID:20436886 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp23 matrix metallopeptidase 23 increases expression ISO Isotretinoin results in increased expression of MMP23B mRNA CTD PMID:20436886 NCBI chr 5:173,078,811...173,082,834
Ensembl chr 5:173,078,590...173,081,839
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
ISO Isotretinoin inhibits the reaction [Arachidonic Acid results in increased expression of MMP9 mRNA]; Isotretinoin inhibits the reaction [Arachidonic Acid results in increased secretion of MMP9 protein]
Isotretinoin results in decreased expression of MMP9 protein
CTD PMID:16185265 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mocos molybdenum cofactor sulfurase decreases expression ISO Isotretinoin results in decreased expression of MOCOS mRNA CTD PMID:20436886 NCBI chr18:16,590,086...16,636,312
Ensembl chr18:16,590,197...16,636,084
JBrowse link
G Mospd1 motile sperm domain containing 1 decreases expression ISO Isotretinoin results in decreased expression of MOSPD1 mRNA CTD PMID:20436886 NCBI chr  X:157,745,939...157,774,505
Ensembl chr  X:157,759,624...157,773,108
JBrowse link
G Mpc1 mitochondrial pyruvate carrier 1 decreases expression ISO Isotretinoin results in decreased expression of MPC1 mRNA CTD PMID:20436886 NCBI chr 1:53,026,608...53,038,229
Ensembl chr 1:53,026,608...53,038,229
JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 decreases expression ISO Isotretinoin results in decreased expression of MPC2 mRNA CTD PMID:20436886 NCBI chr13:83,680,527...83,700,491
Ensembl chr13:83,681,322...83,700,213
JBrowse link
G Mrpl33 mitochondrial ribosomal protein L33 decreases expression ISO Isotretinoin results in decreased expression of MRPL33 mRNA CTD PMID:20436886 NCBI chr 6:26,130,278...26,138,498
Ensembl chr 6:26,130,488...26,138,414
JBrowse link
G Mrps16 mitochondrial ribosomal protein S16 decreases expression ISO Isotretinoin results in decreased expression of MRPS16 mRNA CTD PMID:20436886 NCBI chr15:4,351,292...4,353,694
Ensembl chr15:4,351,292...4,353,694
JBrowse link
G Mrps18a mitochondrial ribosomal protein S18A decreases expression ISO Isotretinoin results in decreased expression of MRPS18A mRNA CTD PMID:20436886 NCBI chr 9:17,238,354...17,254,845
Ensembl chr 9:17,238,385...17,254,949
JBrowse link
G Mrps33 mitochondrial ribosomal protein S33 decreases expression ISO Isotretinoin results in decreased expression of MRPS33 mRNA CTD PMID:20436886 NCBI chr 4:67,606,971...67,616,056
Ensembl chr 4:67,607,273...67,610,710
JBrowse link
G Mrs2 magnesium transporter MRS2 decreases expression ISO Isotretinoin results in decreased expression of MRS2 mRNA CTD PMID:20436886 NCBI chr17:42,064,271...42,083,602
Ensembl chr17:42,064,376...42,082,300
JBrowse link
G Mrtfb myocardin related transcription factor B increases expression ISO Isotretinoin results in increased expression of MRTFB mRNA CTD PMID:20436886 NCBI chr10:1,151,163...1,273,269 JBrowse link
G Msmb microseminoprotein, beta increases expression ISO Isotretinoin results in increased expression of MSMB mRNA CTD PMID:20436886 NCBI chr16:8,280,275...8,300,853
Ensembl chr16:8,280,275...8,300,852
JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases expression ISO Isotretinoin results in decreased expression of MSMO1 mRNA CTD PMID:20436886 NCBI chr16:26,859,441...26,875,880
Ensembl chr16:26,859,397...26,875,973
JBrowse link
G Msrb1 methionine sulfoxide reductase B1 decreases expression ISO Isotretinoin results in decreased expression of MSRB1 mRNA CTD PMID:20436886 NCBI chr10:14,105,750...14,111,463
Ensembl chr10:14,105,750...14,111,463
JBrowse link
G Mtch2 mitochondrial carrier 2 decreases expression ISO Isotretinoin results in decreased expression of MTCH2 mRNA CTD PMID:20436886 NCBI chr 3:79,678,141...79,695,356
Ensembl chr 3:79,678,201...79,694,006
JBrowse link
G Mto1 mitochondrial tRNA translation optimization 1 decreases expression ISO Isotretinoin results in decreased expression of MTO1 mRNA CTD PMID:20436886 NCBI chr 8:85,807,703...85,832,263
Ensembl chr 8:85,808,125...85,831,937
JBrowse link
G Mtx1 Metaxin 1 decreases expression ISO Isotretinoin results in decreased expression of MTX1 mRNA CTD PMID:20436886 NCBI chr 2:188,522,605...188,528,747
Ensembl chr 2:188,521,785...188,528,195
JBrowse link
G Muc1 mucin 1, cell surface associated decreases expression ISO Isotretinoin results in decreased expression of MUC1 mRNA CTD PMID:20436886 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Mvd mevalonate diphosphate decarboxylase decreases expression ISO Isotretinoin results in decreased expression of MVD mRNA CTD PMID:20436886 NCBI chr19:55,258,910...55,268,933
Ensembl chr19:55,258,905...55,268,951
JBrowse link
G Mvk mevalonate kinase decreases expression ISO Isotretinoin results in decreased expression of MVK mRNA CTD PMID:20436886 NCBI chr12:47,904,266...47,920,457
Ensembl chr12:47,904,719...47,919,400
JBrowse link
G Mycbp Myc binding protein decreases expression ISO Isotretinoin results in decreased expression of MYCBP mRNA CTD PMID:20436886 NCBI chr 5:141,560,192...141,567,399
Ensembl chr 5:141,560,192...141,567,399
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor decreases expression
multiple interactions
ISO Isotretinoin results in decreased expression of MYCN mRNA
R116010 promotes the reaction [Isotretinoin results in decreased expression of MYCN mRNA]
CTD PMID:17486130 NCBI chr 6:38,222,554...38,228,419
Ensembl chr 6:38,222,555...38,228,379
JBrowse link
G Myl4 myosin, light chain 4 decreases expression ISO Isotretinoin results in decreased expression of MYL4 mRNA CTD PMID:20436886 NCBI chr10:92,628,356...92,638,100
Ensembl chr10:92,628,356...92,638,100
JBrowse link
G Myod1 myogenic differentiation 1 decreases expression ISO Isotretinoin results in decreased expression of MYOD1 mRNA CTD PMID:20436886 NCBI chr 1:102,396,538...102,399,248
Ensembl chr 1:102,396,538...102,399,248
JBrowse link
G Nadk NAD kinase decreases expression ISO Isotretinoin results in decreased expression of NADK mRNA CTD PMID:20436886 NCBI chr 5:172,984,930...173,015,505
Ensembl chr 5:172,986,291...173,015,494
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase decreases expression ISO Isotretinoin results in decreased expression of NAMPT mRNA CTD PMID:20436886 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Nbn nibrin decreases expression ISO Isotretinoin results in decreased expression of NBN mRNA CTD PMID:20436886 NCBI chr 5:29,622,347...29,656,877
Ensembl chr 5:29,622,281...29,656,864
JBrowse link
G Ndufa3 NADH:ubiquinone oxidoreductase subunit A3 decreases expression ISO Isotretinoin results in decreased expression of NDUFA3 mRNA CTD PMID:20436886 NCBI chr 1:64,172,462...64,175,174
Ensembl chr 1:64,172,540...64,175,099
JBrowse link
G Ndufaf1 NADH:ubiquinone oxidoreductase complex assembly factor 1 decreases expression ISO Isotretinoin results in decreased expression of CIA30 mRNA CTD PMID:20436886 NCBI chr 3:111,458,227...111,469,239
Ensembl chr 3:111,458,572...111,469,518
JBrowse link
G Ndufb3 NADH:ubiquinone oxidoreductase subunit B3 decreases expression ISO Isotretinoin results in decreased expression of NDUFB3 mRNA CTD PMID:20436886 NCBI chr 9:65,478,496...65,488,708
Ensembl chr 9:65,478,496...65,488,702
JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 decreases expression ISO Isotretinoin results in decreased expression of NDUFC2 mRNA CTD PMID:20436886 NCBI chr 1:162,369,801...162,376,024
Ensembl chr 1:162,369,801...162,376,023
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 decreases expression ISO Isotretinoin results in decreased expression of NDUFS1 mRNA CTD PMID:20436886 NCBI chr 9:69,919,863...69,953,182
Ensembl chr 9:69,919,867...69,953,182
JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 decreases expression ISO Isotretinoin results in decreased expression of NDUFS3 mRNA CTD PMID:20436886 NCBI chr 3:79,721,686...79,728,863
Ensembl chr 3:79,721,694...79,728,879
JBrowse link
G Ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 decreases expression ISO Isotretinoin results in decreased expression of NDUFS7 mRNA CTD PMID:20436886 NCBI chr 7:12,318,776...12,326,403
Ensembl chr 7:12,318,757...12,326,392
JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 decreases expression ISO Isotretinoin results in decreased expression of NDUFS8 mRNA CTD PMID:20436886 NCBI chr 1:219,141,289...219,144,610
Ensembl chr 1:219,141,292...219,144,610
JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 decreases expression ISO Isotretinoin results in decreased expression of NDUFV2 mRNA CTD PMID:20436886 NCBI chr 9:113,875,718...113,900,169
Ensembl chr 9:113,875,703...113,900,190
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 increases expression ISO Isotretinoin results in increased expression of NEDD9 mRNA CTD PMID:15982314 NCBI chr17:22,984,792...23,179,701
Ensembl chr17:22,984,844...23,179,701
JBrowse link
G Nefl neurofilament light decreases expression ISO Isotretinoin results in decreased expression of NEFL mRNA CTD PMID:15982314 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Neurog2 neurogenin 2 increases expression ISO Isotretinoin results in increased expression of NEUROG2 mRNA CTD PMID:31711903 NCBI chr 2:231,962,517...231,963,441
Ensembl chr 2:231,962,517...231,963,308
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Isotretinoin affects the localization of and results in decreased activity of NFKB1 protein CTD PMID:18652567 PMID:19066126 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nit2 nitrilase family, member 2 decreases expression ISO Isotretinoin results in decreased expression of NIT2 mRNA CTD PMID:20436886 NCBI chr11:45,462,345...45,473,107
Ensembl chr11:45,462,345...45,473,104
JBrowse link
G Nop16 NOP16 nucleolar protein decreases expression ISO Isotretinoin results in decreased expression of NOP16 mRNA CTD PMID:20436886 NCBI chr17:10,559,811...10,564,728
Ensembl chr17:10,559,680...10,564,733
JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 decreases expression ISO Isotretinoin results in decreased expression of NPC1 mRNA CTD PMID:20436886 NCBI chr18:3,616,878...3,662,656
Ensembl chr18:3,616,878...3,662,683
JBrowse link
G Npl N-acetylneuraminate pyruvate lyase decreases expression ISO Isotretinoin results in decreased expression of NPL mRNA CTD PMID:20436886 NCBI chr13:70,938,073...70,981,179
Ensembl chr13:70,938,082...70,980,913
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 decreases expression ISO Isotretinoin results in decreased expression of NQO2 mRNA CTD PMID:20436886 NCBI chr17:32,131,847...32,158,559
Ensembl chr17:32,132,347...32,158,538
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Isotretinoin inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]; Isotretinoin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO [Isotretinoin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; Isotretinoin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA] CTD PMID:16632523 PMID:25455453 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 increases expression ISO Isotretinoin results in increased expression of NR2F1 mRNA CTD PMID:20436886 NCBI chr 2:5,569,954...5,579,894
Ensembl chr 2:5,569,935...5,579,894
JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like decreases expression ISO Isotretinoin results in decreased expression of NSDHL mRNA CTD PMID:20436886 NCBI chr  X:152,933,118...152,964,399
Ensembl chr  X:152,933,069...152,964,390
JBrowse link
G Ntan1 N-terminal asparagine amidase decreases expression ISO Isotretinoin results in decreased expression of NTAN1 mRNA CTD PMID:20436886 NCBI chr10:3,218,414...3,235,229 JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 increases expression ISO Isotretinoin results in increased expression of NTRK2 mRNA CTD PMID:20436886 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Nudt21 nudix hydrolase 21 decreases expression ISO Isotretinoin results in decreased expression of NUDT21 mRNA CTD PMID:20436886 NCBI chr19:11,451,366...11,470,637
Ensembl chr19:11,450,760...11,467,644
JBrowse link
G Nudt4 nudix hydrolase 4 decreases expression ISO Isotretinoin results in decreased expression of NUDT4 mRNA CTD PMID:20436886 NCBI chr 7:36,643,916...36,660,334
Ensembl chr 7:36,643,916...36,660,141
JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A decreases expression ISO Isotretinoin results in decreased expression of OAS1 mRNA CTD PMID:20436886 NCBI chr12:41,200,680...41,211,393
Ensembl chr12:41,200,718...41,211,909
JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions
decreases expression
ISO Isotretinoin inhibits the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]
Isotretinoin results in decreased expression of ODC1 mRNA
CTD PMID:15225900 PMID:15982314 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Odr4 odr-4 GPCR localization factor homolog decreases expression ISO Isotretinoin results in decreased expression of ODR4 mRNA CTD PMID:20436886 NCBI chr13:67,578,904...67,611,605
Ensembl chr13:67,583,621...67,609,469
JBrowse link
G Olah oleoyl-ACP hydrolase decreases expression ISO Isotretinoin results in decreased expression of OLAH mRNA CTD PMID:20436886 NCBI chr17:78,878,673...78,903,919
Ensembl chr17:78,879,058...78,903,967
JBrowse link
G Olig3 oligodendrocyte transcription factor 3 increases expression ISO Isotretinoin results in increased expression of OLIG3 mRNA CTD PMID:31711903 NCBI chr 1:14,797,766...14,799,835
Ensembl chr 1:14,797,766...14,799,835
JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 decreases expression ISO Isotretinoin results in decreased expression of ORMDL2 mRNA CTD PMID:20436886 NCBI chr 7:3,242,991...3,246,085
Ensembl chr 7:3,242,991...3,246,071
JBrowse link
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 decreases expression ISO Isotretinoin results in decreased expression of OTUB2 mRNA CTD PMID:20436886 NCBI chr 6:127,282,445...127,301,086
Ensembl chr 6:127,282,466...127,301,083
JBrowse link
G Pafah2 platelet-activating factor acetylhydrolase 2 decreases expression ISO Isotretinoin results in decreased expression of PAFAH2 mRNA CTD PMID:20436886 NCBI chr 5:152,606,850...152,635,956
Ensembl chr 5:152,606,847...152,634,803
JBrowse link
G Pank3 pantothenate kinase 3 decreases expression ISO Isotretinoin results in decreased expression of PANK3 mRNA CTD PMID:20436886 NCBI chr10:20,591,432...20,615,258
Ensembl chr10:20,591,432...20,615,258
JBrowse link
G Paqr3 progestin and adipoQ receptor family member 3 decreases expression ISO Isotretinoin results in decreased expression of PAQR3 mRNA CTD PMID:20436886 NCBI chr14:14,107,513...14,129,780
Ensembl chr14:14,107,580...14,124,828
JBrowse link
G Pawr pro-apoptotic WT1 regulator decreases expression ISO Isotretinoin results in decreased expression of PAWR mRNA CTD PMID:20436886 NCBI chr 7:51,273,764...51,353,700
Ensembl chr 7:51,273,771...51,353,068
JBrowse link
G Pax6 paired box 6 increases expression ISO Isotretinoin results in increased expression of PAX6 mRNA CTD PMID:31711903 NCBI chr 3:95,700,241...95,728,682
Ensembl chr 3:95,707,386...95,728,624
JBrowse link
G Pccb propionyl-CoA carboxylase subunit beta decreases expression ISO Isotretinoin results in decreased expression of PCCB mRNA CTD PMID:20436886 NCBI chr 8:109,368,887...109,418,871
Ensembl chr 8:109,368,624...109,418,872
JBrowse link
G Pcdh1 protocadherin 1 multiple interactions ISO [vorinostat co-treated with Isotretinoin] results in increased expression of PCDH1 mRNA CTD PMID:18769122 NCBI chr18:31,330,081...31,343,147
Ensembl chr18:31,328,919...31,343,797
JBrowse link
G Pcolce procollagen C-endopeptidase enhancer increases expression ISO Isotretinoin results in increased expression of PCOLCE mRNA CTD PMID:20436886 NCBI chr12:22,153,995...22,160,311
Ensembl chr12:22,153,983...22,160,337
JBrowse link
G Pctp phosphatidylcholine transfer protein decreases expression ISO Isotretinoin results in decreased expression of PCTP mRNA CTD PMID:20436886 NCBI chr10:77,491,445...77,537,268
Ensembl chr10:77,491,454...77,512,032
JBrowse link
G Pde6a phosphodiesterase 6A decreases expression ISO Isotretinoin results in decreased expression of PDE6A mRNA CTD PMID:20436886 NCBI chr18:56,544,652...56,617,480
Ensembl chr18:56,544,652...56,617,480
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta increases expression ISO Isotretinoin results in increased expression of PDGFRB mRNA CTD PMID:20436886 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 decreases expression ISO Isotretinoin results in decreased expression of PDHA1 mRNA CTD PMID:20436886 NCBI chr  X:37,329,779...37,343,410
Ensembl chr  X:37,329,779...37,343,410
JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta decreases expression ISO Isotretinoin results in decreased expression of PDHB mRNA CTD PMID:20436886 NCBI chr15:18,540,826...18,546,855
Ensembl chr15:18,539,210...18,546,854
JBrowse link
G Pdhx pyruvate dehydrogenase complex, component X decreases expression ISO Isotretinoin results in decreased expression of PDHX mRNA CTD PMID:20436886 NCBI chr 3:92,910,300...92,933,725
Ensembl chr 3:92,909,725...92,969,050
JBrowse link
G Pdzk1 PDZ domain containing 1 decreases expression ISO Isotretinoin results in decreased expression of PDZK1 mRNA CTD PMID:20436886 NCBI chr 2:198,965,685...198,999,323
Ensembl chr 2:198,965,685...198,999,323
JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase decreases expression ISO Isotretinoin results in decreased expression of PECR mRNA CTD PMID:20436886 NCBI chr 9:79,601,937...79,630,547
Ensembl chr 9:79,601,901...79,630,536
JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha decreases expression ISO Isotretinoin results in decreased expression of PEX11A mRNA CTD PMID:20436886 NCBI chr 1:141,474,189...141,481,270
Ensembl chr 1:141,474,180...141,481,315
JBrowse link
G Pex13 peroxisomal biogenesis factor 13 decreases expression ISO Isotretinoin results in decreased expression of PEX13 mRNA CTD PMID:20436886 NCBI chr14:108,394,299...108,411,994
Ensembl chr14:108,394,303...108,412,823
JBrowse link
G Pex16 peroxisomal biogenesis factor 16 decreases expression ISO Isotretinoin results in decreased expression of PEX16 mRNA CTD PMID:20436886 NCBI chr 3:81,283,137...81,292,575
Ensembl chr 3:81,283,137...81,292,573
JBrowse link
G Pex19 peroxisomal biogenesis factor 19 decreases expression ISO Isotretinoin results in decreased expression of PEX19 mRNA CTD PMID:20436886 NCBI chr13:90,514,324...90,530,825
Ensembl chr13:90,514,336...90,530,349
JBrowse link
G Pex3 peroxisomal biogenesis factor 3 decreases expression ISO Isotretinoin results in decreased expression of PEX3 mRNA CTD PMID:20436886 NCBI chr 1:7,685,209...7,726,238
Ensembl chr 1:7,685,338...7,726,401
JBrowse link
G Pex7 peroxisomal biogenesis factor 7 decreases expression ISO Isotretinoin results in decreased expression of PEX7 mRNA CTD PMID:20436886 NCBI chr 1:15,311,768...15,374,702
Ensembl chr 1:15,311,770...15,374,850
JBrowse link
G Pgd phosphogluconate dehydrogenase decreases expression ISO Isotretinoin results in decreased expression of PGD mRNA CTD PMID:20436886 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Pgm1 phosphoglucomutase 1 decreases expression ISO Isotretinoin results in decreased expression of PGM1 mRNA CTD PMID:20436886 NCBI chr 5:118,743,632...118,803,055
Ensembl chr 5:118,743,632...118,803,055
JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 decreases expression ISO Isotretinoin results in decreased expression of PGRMC1 mRNA CTD PMID:20436886 NCBI chr  X:123,205,869...123,213,880
Ensembl chr  X:123,205,869...123,213,882
JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases expression ISO Isotretinoin results in increased expression of PHGDH mRNA CTD PMID:20436886 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 multiple interactions ISO [vorinostat co-treated with Isotretinoin] results in increased expression of PHLDA1 mRNA CTD PMID:18769122 NCBI chr 7:54,247,460...54,249,664
Ensembl chr 7:54,247,460...54,249,664
JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 decreases expression ISO Isotretinoin results in decreased expression of PHLDA2 mRNA CTD PMID:20436886 NCBI chr 1:216,701,345...216,704,479
Ensembl chr 1:216,702,319...216,703,534
JBrowse link
G Pik3c2g phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma decreases expression ISO Isotretinoin results in decreased expression of PIK3C2G mRNA CTD PMID:20436886 NCBI chr 4:173,732,196...174,102,502
Ensembl chr 4:173,732,248...174,102,496
JBrowse link
G Pir pirin decreases expression
increases expression
ISO Isotretinoin results in decreased expression of PIR mRNA
Isotretinoin results in increased expression of PIR mRNA
CTD PMID:15982314 PMID:20436886 NCBI chr  X:31,852,322...31,968,152
Ensembl chr  X:31,852,323...31,968,152
JBrowse link
G Pklr pyruvate kinase L/R decreases expression ISO Isotretinoin results in decreased expression of PKLR mRNA CTD PMID:20436886 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
JBrowse link
G Pkp1 plakophilin 1 increases expression ISO Isotretinoin results in increased expression of PKP1 mRNA CTD PMID:20436886 NCBI chr13:52,705,174...52,753,089
Ensembl chr13:52,705,174...52,752,997
JBrowse link
G Pla2g7 phospholipase A2 group VII decreases expression ISO Isotretinoin results in decreased expression of PLA2G7 mRNA CTD PMID:20436886 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
JBrowse link
G Plat plasminogen activator, tissue type increases expression ISO Isotretinoin results in increased expression of PLAT mRNA CTD PMID:15982314 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plcl2 phospholipase C-like 2 increases expression ISO Isotretinoin results in increased expression of PLCL2 mRNA CTD PMID:20436886 NCBI chr 9:1,782,536...1,984,654
Ensembl chr 9:1,782,536...1,984,654
JBrowse link
G Plin2 perilipin 2 decreases expression ISO Isotretinoin results in decreased expression of PLIN2 mRNA CTD PMID:20436886 NCBI chr 5:104,984,413...105,010,863
Ensembl chr 5:104,984,414...105,010,857
JBrowse link
G Plpp3 phospholipid phosphatase 3 increases expression ISO Isotretinoin results in increased expression of PLPP3 mRNA CTD PMID:20436886 NCBI chr 5:124,690,214...124,765,499
Ensembl chr 5:124,690,214...124,765,498
JBrowse link
G Pltp phospholipid transfer protein increases expression ISO Isotretinoin results in increased expression of PLTP mRNA CTD PMID:20436886 NCBI chr 3:161,304,469...161,322,289
Ensembl chr 3:161,304,469...161,322,289
JBrowse link
G Pmel premelanosome protein decreases expression ISO Isotretinoin results in decreased expression of PMEL mRNA CTD PMID:20436886 NCBI chr 7:3,133,347...3,143,827
Ensembl chr 7:3,133,506...3,143,911
JBrowse link
G Pmpcb peptidase, mitochondrial processing subunit beta decreases expression ISO Isotretinoin results in decreased expression of PMPCB mRNA CTD PMID:20436886 NCBI chr 4:9,908,838...9,921,615
Ensembl chr 4:9,908,831...9,921,610
JBrowse link
G Pmvk phosphomevalonate kinase decreases expression ISO Isotretinoin results in decreased expression of PMVK mRNA CTD PMID:20436886 NCBI chr 2:188,784,329...188,793,890
Ensembl chr 2:188,784,222...188,793,895
JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 decreases expression ISO Isotretinoin results in decreased expression of PNPLA3 mRNA CTD PMID:20436886 NCBI chr 7:125,034,760...125,056,165
Ensembl chr 7:125,034,764...125,055,976
JBrowse link
G Polr2m RNA polymerase II subunit M increases expression ISO Isotretinoin results in increased expression of POLR2M mRNA CTD PMID:20436886 NCBI chr 8:77,985,190...77,992,621
Ensembl chr 8:77,985,190...78,096,390
JBrowse link
G Pon3 paraoxonase 3 decreases expression ISO Isotretinoin results in decreased expression of PON3 mRNA CTD PMID:20436886 NCBI chr 4:30,311,981...30,338,679
Ensembl chr 4:30,311,982...30,338,679
JBrowse link
G Popdc2 popeye domain containing 2 decreases expression ISO Isotretinoin results in decreased expression of POPDC2 mRNA CTD PMID:20436886 NCBI chr11:64,915,041...64,954,704
Ensembl chr11:64,936,692...64,952,687
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression EXP Isotretinoin results in increased expression of PPARG mRNA CTD PMID:19041696 PMID:19212007 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppif peptidylprolyl isomerase F decreases expression ISO Isotretinoin results in decreased expression of PPIF mRNA CTD PMID:20436886 NCBI chr16:1,979,191...1,985,912
Ensembl chr16:1,979,191...1,985,908
JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B decreases expression ISO Isotretinoin results in decreased expression of PPM1B mRNA CTD PMID:20436886 NCBI chr 6:8,219,385...8,280,127
Ensembl chr 6:8,218,696...8,280,124
JBrowse link
G Ppp1r16b protein phosphatase 1, regulatory subunit 16B increases expression ISO Isotretinoin results in increased expression of PPP1R16B mRNA CTD PMID:20436886 NCBI chr 3:155,160,474...155,267,002
Ensembl chr 3:155,160,481...155,262,941
JBrowse link
G Prdx2 peroxiredoxin 2 decreases expression ISO Isotretinoin results in decreased expression of PRDX2 mRNA CTD PMID:20436886 NCBI chr19:26,084,816...26,090,095
Ensembl chr19:26,084,903...26,090,094
JBrowse link
G Prepl prolyl endopeptidase-like decreases expression ISO Isotretinoin results in decreased expression of PREPL mRNA CTD PMID:20436886 NCBI chr 6:8,316,861...8,346,293
Ensembl chr 6:8,318,979...8,346,197
JBrowse link
G Pros1 protein S increases expression ISO Isotretinoin results in increased expression of PROS1 mRNA CTD PMID:20436886 NCBI chr 7:1,206,648...1,288,140
Ensembl chr 7:1,206,648...1,288,134
JBrowse link
G Prss8 serine protease 8 decreases expression ISO Isotretinoin results in decreased expression of PRSS8 mRNA CTD PMID:20436886 NCBI chr 1:199,372,519...199,377,035
Ensembl chr 1:199,372,519...199,377,035
JBrowse link
G Psma1 proteasome 20S subunit alpha 1 decreases expression ISO Isotretinoin results in decreased expression of PSMA1 mRNA CTD PMID:20436886 NCBI chr 1:183,733,567...183,744,586
Ensembl chr 1:183,733,567...183,744,586
JBrowse link
G Psma3 proteasome 20S subunit alpha 3 decreases expression ISO Isotretinoin results in decreased expression of PSMA3 mRNA CTD PMID:20436886 NCBI chr 6:93,423,029...93,444,223
Ensembl chr 6:93,423,002...93,444,240
JBrowse link
G Psma4 proteasome 20S subunit alpha 4 decreases expression ISO Isotretinoin results in decreased expression of PSMA4 mRNA CTD PMID:20436886 NCBI chr 8:59,532,456...59,539,916
Ensembl chr 8:59,532,389...59,539,920
JBrowse link
G Psma5 proteasome 20S subunit alpha 5 decreases expression ISO Isotretinoin results in decreased expression of PSMA5 mRNA CTD PMID:20436886 NCBI chr 2:211,050,344...211,073,706
Ensembl chr 2:211,050,360...211,073,714
JBrowse link
G Psma7 proteasome 20S subunit alpha 7 decreases expression ISO Isotretinoin results in decreased expression of PSMA7 mRNA CTD PMID:20436886 NCBI chr 3:175,420,042...175,426,384
Ensembl chr 3:175,420,039...175,426,395
JBrowse link
G Psmb5 proteasome 20S subunit beta 5 decreases expression ISO Isotretinoin results in decreased expression of PSMB5 mRNA CTD PMID:20436886 NCBI chr15:33,259,039...33,263,634
Ensembl chr15:33,259,043...33,263,659
JBrowse link
G Ptgds prostaglandin D2 synthase increases expression ISO Isotretinoin results in increased expression of PTGDS mRNA CTD PMID:20436886 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO Isotretinoin results in decreased expression of PTGS1 mRNA CTD PMID:15982314 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Isotretinoin results in decreased expression of PTGS2 mRNA CTD PMID:15982314 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptprb protein tyrosine phosphatase, receptor type, B increases expression ISO Isotretinoin results in increased expression of PTPRB mRNA CTD PMID:20436886 NCBI chr 7:59,326,484...59,431,114
Ensembl chr 7:59,326,518...59,425,718
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C increases expression ISO Isotretinoin results in increased expression of PTPRC mRNA CTD PMID:20436886 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
G Ptprg protein tyrosine phosphatase, receptor type, G increases expression ISO Isotretinoin results in increased expression of PTPRG mRNA CTD PMID:20436886 NCBI chr15:12,926,056...13,633,839
Ensembl chr15:12,926,167...13,228,607
JBrowse link
G Ptprm protein tyrosine phosphatase, receptor type, M increases expression ISO Isotretinoin results in increased expression of PTPRM mRNA CTD PMID:20436886 NCBI chr 9:114,846,095...115,555,261
Ensembl chr 9:114,846,095...115,555,261
JBrowse link
G Ptrh2 peptidyl-tRNA hydrolase 2 decreases expression ISO Isotretinoin results in decreased expression of PTRH2 mRNA CTD PMID:20436886 NCBI chr10:74,002,151...74,012,182
Ensembl chr10:74,002,151...74,012,159
JBrowse link
G Pts 6-pyruvoyl-tetrahydropterin synthase decreases expression ISO Isotretinoin results in decreased expression of PTS mRNA CTD PMID:20436886 NCBI chr 8:54,954,261...54,961,271
Ensembl chr 8:54,954,226...54,961,265
JBrowse link
G Pxmp2 peroxisomal membrane protein 2 decreases expression ISO Isotretinoin results in decreased expression of PXMP2 mRNA CTD PMID:20436886 NCBI chr12:52,452,354...52,462,655
Ensembl chr12:52,452,273...52,462,659
JBrowse link
G Pxmp4 peroxisomal membrane protein 4 decreases expression ISO Isotretinoin results in decreased expression of PXMP4 mRNA CTD PMID:20436886 NCBI chr 3:150,091,646...150,108,893
Ensembl chr 3:150,091,630...150,108,898
JBrowse link
G Qk quaking increases expression ISO Isotretinoin results in increased expression of QKI mRNA CTD PMID:20436886 NCBI chr 1:50,983,647...51,050,692 JBrowse link
G Rab27a RAB27A, member RAS oncogene family decreases expression ISO Isotretinoin results in decreased expression of RAB27A mRNA CTD PMID:20436886 NCBI chr 8:79,722,334...79,776,228
Ensembl chr 8:79,722,334...79,776,221
JBrowse link
G Rab38 RAB38, member RAS oncogene family decreases expression ISO Isotretinoin results in decreased expression of RAB38 mRNA CTD PMID:20436886 NCBI chr 1:152,072,716...152,153,449
Ensembl chr 1:152,072,665...152,153,449
JBrowse link
G Rab5if RAB5 interacting factor decreases expression ISO Isotretinoin results in decreased expression of RAB5IF mRNA CTD PMID:20436886 NCBI chr 3:152,933,771...152,943,780
Ensembl chr 3:152,933,771...152,943,777
JBrowse link
G Rac2 Rac family small GTPase 2 increases expression ISO Isotretinoin results in increased expression of RAC2 mRNA CTD PMID:20436886 NCBI chr 7:119,769,708...119,797,111
Ensembl chr 7:119,783,849...119,797,098
JBrowse link
G Rara retinoic acid receptor, alpha increases expression
decreases expression
ISO
EXP
Isotretinoin results in increased expression of RARA mRNA
Isotretinoin results in decreased expression of RARA mRNA
CTD PMID:9262057 PMID:19041696 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rarb retinoic acid receptor, beta multiple interactions
decreases expression
increases expression
ISO
EXP
[LAQ824 co-treated with Isotretinoin] results in increased acetylation of RARB promoter; [LAQ824 co-treated with Isotretinoin] results in increased expression of RARB mRNA; R116010 promotes the reaction [Isotretinoin results in increased expression of RARB mRNA]
Isotretinoin results in decreased expression of RARB mRNA
CTD PMID:17237267 PMID:17486130 PMID:19041696 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599
JBrowse link
G Rarg retinoic acid receptor, gamma decreases expression EXP Isotretinoin results in decreased expression of RARG mRNA CTD PMID:19041696 NCBI chr 7:143,840,739...143,863,206
Ensembl chr 7:143,839,980...143,863,186
JBrowse link
G Rarres1 retinoic acid receptor responder 1 multiple interactions
increases expression
ISO AGN 193109 inhibits the reaction [Isotretinoin results in increased expression of RARRES1 mRNA] CTD PMID:16575387 NCBI chr 2:164,650,722...164,684,982
Ensembl chr 2:164,650,722...164,684,985
JBrowse link
G Rasal1 RAS protein activator like 1 decreases expression ISO Isotretinoin results in decreased expression of RASAL1 mRNA CTD PMID:20436886 NCBI chr12:41,416,218...41,449,445
Ensembl chr12:41,416,218...41,448,668
JBrowse link
G Rassf2 Ras association domain family member 2 increases expression ISO Isotretinoin results in increased expression of RASSF2 mRNA CTD PMID:20436886 NCBI chr 3:124,574,088...124,610,267
Ensembl chr 3:124,575,621...124,610,267
JBrowse link
G Rbks ribokinase decreases expression ISO Isotretinoin results in decreased expression of RBKS mRNA CTD PMID:20436886 NCBI chr 6:26,051,568...26,128,762
Ensembl chr 6:26,051,396...26,128,906
JBrowse link
G Rbm47 RNA binding motif protein 47 decreases expression ISO Isotretinoin results in decreased expression of RBM47 mRNA CTD PMID:20436886 NCBI chr14:43,701,944...43,839,803
Ensembl chr14:43,810,119...43,837,662
JBrowse link
G Rbpms RNA binding protein, mRNA processing factor increases expression ISO Isotretinoin results in increased expression of RBPMS mRNA CTD PMID:20436886 NCBI chr16:61,954,569...62,109,998
Ensembl chr16:61,954,590...62,096,497
JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 decreases expression ISO Isotretinoin results in decreased expression of RC3H2 mRNA CTD PMID:20436886 NCBI chr 3:21,621,976...21,676,789
Ensembl chr 3:21,623,041...21,670,014
JBrowse link
G Rdh11 retinol dehydrogenase 11 decreases expression ISO Isotretinoin results in decreased expression of RDH11 mRNA CTD PMID:20436886 NCBI chr 6:102,356,498...102,372,618
Ensembl chr 6:102,356,492...102,372,611
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions ISO Isotretinoin affects the localization of and results in decreased activity of REL protein CTD PMID:18652567 PMID:19066126 NCBI chr14:108,490,794...108,517,582
Ensembl chr14:108,491,069...108,509,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Isotretinoin affects the localization of and results in decreased activity of RELA protein CTD PMID:18652567 PMID:19066126 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Retreg1 reticulophagy regulator 1 decreases expression ISO Isotretinoin results in decreased expression of RETREG1 mRNA CTD PMID:20436886 NCBI chr 2:78,391,921...78,401,569
Ensembl chr 2:78,391,921...78,399,987
JBrowse link
G Rfk riboflavin kinase decreases expression ISO Isotretinoin results in decreased expression of RFK mRNA CTD PMID:20436886 NCBI chr 1:236,494,221...236,501,733
Ensembl chr 1:236,494,221...236,501,733
JBrowse link
G RGD1309104 similar to RIKEN cDNA 1700025G04 gene increases expression ISO Isotretinoin results in increased expression of C1ORF21 mRNA CTD PMID:20436886 NCBI chr13:69,265,649...69,434,447
Ensembl chr13:69,265,649...69,385,074
JBrowse link
G RGD1559459 similar to Expressed sequence AI788959 decreases expression ISO Isotretinoin results in decreased expression of UGT2B28 mRNA CTD PMID:20436886 NCBI chr14:22,932,454...22,955,663
Ensembl chr14:22,937,421...22,952,822
JBrowse link
G RGD1561113 similar to Hypothetical UPF0184 protein C9orf16 homolog decreases expression ISO Isotretinoin results in decreased expression of BBLN mRNA CTD PMID:20436886 NCBI chr 3:11,408,076...11,410,907
Ensembl chr 3:11,408,348...11,410,732
JBrowse link
G Rhoa ras homolog family member A decreases expression ISO Isotretinoin results in decreased expression of RHOA mRNA CTD PMID:15982314 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G Rhob ras homolog family member B decreases expression ISO Isotretinoin results in decreased expression of RHOB mRNA CTD PMID:15982314 NCBI chr 6:33,689,127...33,691,301
Ensembl chr 6:33,689,127...33,691,301
JBrowse link
G Rhobtb3 Rho-related BTB domain containing 3 increases expression ISO Isotretinoin results in increased expression of RHOBTB3 mRNA CTD PMID:20436886 NCBI chr 2:2,627,655...2,683,305
Ensembl chr 2:2,627,393...2,683,116
JBrowse link
G Rida reactive intermediate imine deaminase A homolog decreases expression ISO Isotretinoin results in decreased expression of UK114 mRNA CTD PMID:20436886 NCBI chr 7:73,256,506...73,270,308
Ensembl chr 7:73,256,508...73,270,308
JBrowse link
G Riox2 ribosomal oxygenase 2 decreases expression ISO Isotretinoin results in decreased expression of RIOX2 mRNA CTD PMID:20436886 NCBI chr11:43,006,190...43,028,722
Ensembl chr11:43,006,757...43,022,565
JBrowse link
G Rmdn1 regulator of microtubule dynamics 1 decreases expression ISO Isotretinoin results in decreased expression of RMDN1 mRNA CTD PMID:20436886 NCBI chr 5:33,580,891...33,604,564
Ensembl chr 5:33,580,944...33,638,165
JBrowse link
G Rnaset2 ribonuclease T2 increases expression ISO Isotretinoin results in increased expression of RNASET2 mRNA CTD PMID:20436886 NCBI chr 1:53,174,879...53,192,048
Ensembl chr 1:53,174,879...53,192,048
JBrowse link
G Rnd3 Rho family GTPase 3 decreases expression ISO Isotretinoin results in decreased expression of RND3 mRNA CTD PMID:20436886 NCBI chr 3:36,643,374...36,660,727
Ensembl chr 3:36,642,587...36,660,758
JBrowse link
G Rnf128 ring finger protein 128 decreases expression ISO Isotretinoin results in decreased expression of RNF128 mRNA CTD PMID:20436886 NCBI chr  X:110,789,061...110,877,964
Ensembl chr  X:110,789,269...110,877,978
JBrowse link
G Rnf38 ring finger protein 38 increases expression ISO Isotretinoin results in increased expression of RNF38 mRNA CTD PMID:20436886 NCBI chr 5:59,604,783...59,713,108
Ensembl chr 5:59,607,476...59,647,633
JBrowse link
G Rnf5 ring finger protein 5 decreases expression ISO Isotretinoin results in decreased expression of RNF5 mRNA CTD PMID:15982314 NCBI chr20:4,366,244...4,368,690
Ensembl chr20:4,366,246...4,368,693
JBrowse link
G Ro60 Ro60, Y RNA binding protein decreases expression ISO Isotretinoin results in decreased expression of RO60 mRNA CTD PMID:20436886 NCBI chr13:60,546,892...60,567,882
Ensembl chr13:60,546,912...60,567,882
JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 increases expression ISO Isotretinoin results in increased expression of ROR1 mRNA CTD PMID:20436886 NCBI chr 5:118,892,874...119,239,528
Ensembl chr 5:119,097,715...119,241,733
JBrowse link
G Rora RAR-related orphan receptor A decreases expression ISO Isotretinoin results in decreased expression of RORA mRNA CTD PMID:20436886 NCBI chr 8:75,515,886...75,616,477
Ensembl chr 8:75,516,904...75,607,212
JBrowse link
G Rpe65 retinoid isomerohydrolase RPE65 multiple interactions ISO
EXP
[Isotretinoin binds to and results in decreased activity of RPE65 protein] which results in decreased abundance of Retinaldehyde CTD PMID:16411761 NCBI chr 2:266,141,581...266,169,197
Ensembl chr 2:266,141,581...266,169,197
JBrowse link
G Rpp40 ribonuclease P/MRP subunit p40 decreases expression ISO Isotretinoin results in decreased expression of RPP40 mRNA CTD PMID:20436886 NCBI chr17:29,638,647...29,647,709
Ensembl chr17:29,638,677...29,647,763
JBrowse link
G RT1-Bb RT1 class II, locus Bb increases expression ISO Isotretinoin results in increased expression of HLA-DQB1 mRNA CTD PMID:20436886 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 increases expression ISO Isotretinoin results in increased expression of HLA-F mRNA CTD PMID:20436886 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
G RT1-Ha RT1 class II, locus Ha increases expression ISO Isotretinoin results in increased expression of HLA-DPA1 mRNA CTD PMID:20436886 NCBI chr20:3,875,478...3,885,140
Ensembl chr20:3,875,706...3,881,461
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 increases expression ISO Isotretinoin results in increased expression of HLA-E mRNA CTD PMID:20436886 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
G Rtca RNA 3'-terminal phosphate cyclase decreases expression ISO Isotretinoin results in decreased expression of RTCA mRNA CTD PMID:20436886 NCBI chr 2:219,537,213...219,558,489
Ensembl chr 2:219,537,206...219,558,675
JBrowse link
G Rtn1 reticulon 1 increases expression ISO Isotretinoin results in increased expression of RTN1 mRNA CTD PMID:20436886 NCBI chr 6:94,951,016...95,177,477
Ensembl chr 6:94,951,020...95,061,174
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions
affects binding
increases activity
ISO
EXP
Isotretinoin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]
Isotretinoin binds to RXRA protein
Isotretinoin results in increased activity of RXRA protein
CTD PMID:16632523 PMID:21543282 PMID:31566444 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Rxrb retinoid X receptor beta decreases expression EXP Isotretinoin results in decreased expression of RXRB mRNA CTD PMID:19041696 NCBI chr20:3,822,673...3,829,138
Ensembl chr20:3,823,042...3,829,140
JBrowse link
G S100a1 S100 calcium binding protein A1 decreases expression ISO Isotretinoin results in decreased expression of S100A1 mRNA CTD PMID:15982314 NCBI chr 2:189,900,505...189,905,348
Ensembl chr 2:189,900,667...189,903,219
JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression ISO Isotretinoin results in increased expression of S100A4 mRNA CTD PMID:20436886 NCBI chr 2:189,997,278...189,999,587
Ensembl chr 2:189,997,129...189,999,604
JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO Isotretinoin results in increased expression of S100A8 mRNA CTD PMID:15982314 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO Isotretinoin results in increased expression of S100A9 mRNA CTD PMID:15982314 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
JBrowse link
G Samm50 SAMM50 sorting and assembly machinery component decreases expression ISO Isotretinoin results in decreased expression of SAMM50 mRNA CTD PMID:20436886 NCBI chr 7:125,058,966...125,082,506
Ensembl chr 7:125,058,897...125,082,505
JBrowse link
G Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 increases expression ISO Isotretinoin results in increased expression of SAMSN1 mRNA CTD PMID:20436886 NCBI chr11:14,252,088...14,405,825
Ensembl chr11:14,253,848...14,304,725
JBrowse link
G Sar1b secretion associated, Ras related GTPase 1B decreases expression ISO Isotretinoin results in decreased expression of SAR1B mRNA CTD PMID:20436886 NCBI chr10:37,215,989...37,245,603
Ensembl chr10:37,215,937...37,245,658
JBrowse link
G Sc5d sterol-C5-desaturase decreases expression ISO Isotretinoin results in decreased expression of SC5D mRNA CTD PMID:20436886 NCBI chr 8:46,525,406...46,537,014
Ensembl chr 8:46,525,400...46,537,050
JBrowse link
G Scamp1 secretory carrier membrane protein 1 decreases expression ISO Isotretinoin results in decreased expression of SCAMP1 mRNA CTD PMID:20436886 NCBI chr 2:23,858,021...23,941,128
Ensembl chr 2:23,857,995...23,941,084
JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha increases expression ISO Isotretinoin results in increased expression of SCNN1A mRNA CTD PMID:18769122 NCBI chr 4:157,834,339...157,860,472
Ensembl chr 4:157,836,912...157,860,049
JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 decreases expression ISO Isotretinoin results in decreased expression of SDF2L1 mRNA CTD PMID:20436886 NCBI chr11:88,122,271...88,124,513
Ensembl chr11:88,122,271...88,124,513
JBrowse link
G Sdhc succinate dehydrogenase complex subunit C decreases expression ISO Isotretinoin results in decreased expression of SDHC mRNA CTD PMID:20436886 NCBI chr13:89,498,047...89,518,979
Ensembl chr13:89,498,048...89,518,939
JBrowse link
G Selplg selectin P ligand increases expression ISO Isotretinoin results in increased expression of SELPLG mRNA CTD PMID:20436886 NCBI chr12:48,577,905...48,579,196
Ensembl chr12:48,577,905...48,579,196
JBrowse link
G Septin11 septin 11 decreases expression ISO Isotretinoin results in decreased expression of SEPTIN11 mRNA CTD PMID:20436886 NCBI chr14:16,369,544...16,405,645
Ensembl chr14:16,369,544...16,452,998
JBrowse link
G Serhl2 serine hydrolase-like 2 increases expression ISO Isotretinoin results in increased expression of SERHL2 mRNA CTD PMID:20436886 NCBI chr 7:123,963,381...123,990,103
Ensembl chr 7:123,963,381...123,990,103
JBrowse link
G Serpinb2 serpin family B member 2 decreases expression ISO Isotretinoin results in decreased expression of SERPINB2 mRNA CTD PMID:15982314 NCBI chr13:27,449,907...27,463,015
Ensembl chr13:27,449,934...27,463,010
JBrowse link
G Serpinb8 serpin family B member 8 decreases expression ISO Isotretinoin results in decreased expression of SERPINB8 mRNA CTD PMID:15982314 NCBI chr13:27,876,662...27,914,038
Ensembl chr13:27,889,345...27,914,006
JBrowse link
G Serpinb9 serpin family B member 9 decreases expression ISO Isotretinoin results in decreased expression of SERPINB9 mRNA CTD PMID:15982314 NCBI chr17:32,648,846...32,673,047
Ensembl chr17:32,650,441...32,661,865
JBrowse link
G Serpine1 serpin family E member 1 decreases expression EXP Isotretinoin results in decreased expression of SERPINE1 mRNA CTD PMID:15972972 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Serping1 serpin family G member 1 increases expression ISO Isotretinoin results in increased expression of SERPING1 mRNA CTD PMID:20436886 NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078
JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 decreases expression ISO Isotretinoin results in decreased expression of SGK2 mRNA CTD PMID:20436886 NCBI chr 3:159,361,313...159,385,843
Ensembl chr 3:159,368,273...159,384,775
JBrowse link
G Shh sonic hedgehog signaling molecule increases expression ISO Isotretinoin results in increased expression of SHH mRNA CTD PMID:26096596 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 decreases expression ISO Isotretinoin results in decreased expression of SHMT1 mRNA CTD PMID:20436886 NCBI chr10:47,030,813...47,059,216
Ensembl chr10:47,031,050...47,059,216
JBrowse link
G Sirpa signal-regulatory protein alpha increases expression ISO Isotretinoin results in increased expression of SIRPA mRNA CTD PMID:20436886 NCBI chr 3:122,113,735...122,152,478
Ensembl chr 3:122,114,108...122,152,477
JBrowse link
G Sla src-like adaptor increases expression ISO Isotretinoin results in increased expression of SLA mRNA CTD PMID:20436886 NCBI chr 7:107,585,055...107,604,950
Ensembl chr 7:107,584,118...107,634,335
JBrowse link
G Slc11a2 solute carrier family 11 member 2 decreases expression ISO Isotretinoin results in decreased expression of SLC11A2 mRNA CTD PMID:20436886 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212
JBrowse link
G Slc15a1 solute carrier family 15 member 1 decreases expression ISO Isotretinoin results in decreased expression of SLC15A1 mRNA CTD PMID:20436886 NCBI chr15:106,800,081...106,844,668
Ensembl chr15:106,800,081...106,844,426
JBrowse link
G Slc16a1 solute carrier family 16 member 1 decreases expression ISO Isotretinoin results in decreased expression of SLC16A1 mRNA CTD PMID:15982314 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554
JBrowse link
G Slc16a7 solute carrier family 16 member 7 decreases expression ISO Isotretinoin results in decreased expression of SLC16A7 mRNA CTD PMID:20436886 NCBI chr 7:68,438,341...68,606,312
Ensembl chr 7:68,446,193...68,549,763
JBrowse link
G Slc22a18 solute carrier family 22, member 18 decreases expression ISO Isotretinoin results in decreased expression of SLC22A18 mRNA CTD PMID:20436886 NCBI chr 1:216,676,330...216,700,632
Ensembl chr 1:216,677,373...216,700,641
JBrowse link
G Slc25a11 solute carrier family 25 member 11 decreases expression ISO Isotretinoin results in decreased expression of SLC25A11 mRNA CTD PMID:20436886 NCBI chr10:57,265,903...57,268,018
Ensembl chr10:57,265,704...57,268,081
JBrowse link
G Slc25a15 solute carrier family 25 member 15 decreases expression ISO Isotretinoin results in decreased expression of SLC25A15 mRNA CTD PMID:20436886 NCBI chr16:74,505,318...74,554,523
Ensembl chr16:74,531,564...74,554,529
JBrowse link
G Slc25a16 solute carrier family 25 member 16 decreases expression ISO Isotretinoin results in decreased expression of SLC25A16 mRNA CTD PMID:20436886 NCBI chr20:27,283,383...27,308,069
Ensembl chr20:27,254,984...27,308,069
JBrowse link
G Slc25a17 solute carrier family 25 member 17 decreases expression ISO Isotretinoin results in decreased expression of SLC25A17 mRNA CTD PMID:20436886 NCBI chr 7:122,539,293...122,581,777
Ensembl chr 7:122,539,293...122,581,777
JBrowse link
G Slc26a3 solute carrier family 26 member 3 decreases expression ISO Isotretinoin results in decreased expression of SLC26A3 mRNA CTD PMID:20436886 NCBI chr 6:50,725,085...50,766,306
Ensembl chr 6:50,725,085...50,766,300
JBrowse link
G Slc27a2 solute carrier family 27 member 2 decreases expression ISO Isotretinoin results in decreased expression of SLC27A2 mRNA CTD PMID:20436886 NCBI chr 3:119,014,620...119,052,531
Ensembl chr 3:119,014,620...119,052,531
JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression EXP Isotretinoin results in increased expression of SLC2A4 mRNA CTD PMID:19212007 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Slc30a1 solute carrier family 30 member 1 decreases expression ISO Isotretinoin results in decreased expression of SLC30A1 mRNA CTD PMID:20436886 NCBI chr13:110,677,810...110,681,683
Ensembl chr13:110,677,810...110,681,683
JBrowse link
G Slc30a10 solute carrier family 30, member 10 decreases expression ISO Isotretinoin results in decreased expression of SLC30A10 mRNA CTD PMID:20436886 NCBI chr13:103,396,295...103,406,759
Ensembl chr13:103,396,314...103,410,363
JBrowse link
G Slc31a1 solute carrier family 31 member 1 decreases expression ISO Isotretinoin results in decreased expression of SLC31A1 mRNA CTD PMID:20436886 NCBI chr 5:78,222,504...78,249,358
Ensembl chr 5:78,222,504...78,249,358
JBrowse link
G Slc35a2 solute carrier family 35 member A2 decreases expression ISO Isotretinoin results in decreased expression of SLC35A2 mRNA CTD PMID:20436886 NCBI chr  X:15,453,184...15,461,990
Ensembl chr  X:15,453,186...15,461,713
JBrowse link
G Slc35b1 solute carrier family 35, member B1 decreases expression ISO Isotretinoin results in decreased expression of SLC35B1 mRNA CTD PMID:20436886 NCBI chr10:83,201,532...83,208,605
Ensembl chr10:83,201,311...83,208,605
JBrowse link
G Slc39a14 solute carrier family 39 member 14 increases expression ISO Isotretinoin results in increased expression of SLC39A14 mRNA CTD PMID:20436886 NCBI chr15:51,982,872...52,029,841
Ensembl chr15:51,982,982...52,029,816
JBrowse link
G Slc39a8 solute carrier family 39 member 8 decreases expression ISO Isotretinoin results in decreased expression of SLC39A8 mRNA CTD PMID:20436886 NCBI chr 2:241,028,851...241,092,584
Ensembl chr 2:241,029,693...241,092,582
JBrowse link
G Slc46a3 solute carrier family 46, member 3 decreases expression ISO Isotretinoin results in decreased expression of SLC46A3 mRNA CTD PMID:20436886 NCBI chr12:8,725,479...8,741,944
Ensembl chr12:8,725,517...8,741,951
JBrowse link
G Slc50a1 solute carrier family 50 member 1 decreases expression ISO Isotretinoin results in decreased expression of SLC50A1 mRNA CTD PMID:20436886 NCBI chr 2:188,585,118...188,587,498
Ensembl chr 2:188,585,118...188,587,498
JBrowse link
G Slc5a6 solute carrier family 5 member 6 decreases expression ISO Isotretinoin results in decreased expression of SLC5A6 mRNA CTD PMID:20436886 NCBI chr 6:26,685,823...26,697,110
Ensembl chr 6:26,686,033...26,697,116
JBrowse link
G Slc7a5 solute carrier family 7 member 5 decreases expression ISO Isotretinoin results in decreased expression of SLC7A5 mRNA CTD PMID:20436886 NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563
JBrowse link
G Slco4c1 solute carrier organic anion transporter family, member 4C1 decreases expression ISO Isotretinoin results in decreased expression of SLCO4C1 mRNA CTD PMID:20436886 NCBI chr 9:104,301,935...104,350,262
Ensembl chr 9:104,299,277...104,350,308
JBrowse link
G Slit3 slit guidance ligand 3 increases expression ISO Isotretinoin results in increased expression of SLIT3 mRNA CTD PMID:20436886 NCBI chr10:19,924,200...20,517,918
Ensembl chr10:20,320,878...20,518,518
JBrowse link
G Smyd3 SET and MYND domain containing 3 increases expression ISO Isotretinoin results in increased expression of SMYD3 mRNA CTD PMID:20436886 NCBI chr13:97,330,120...97,807,813 JBrowse link
G Sned1 sushi, nidogen and EGF-like domains 1 increases expression ISO Isotretinoin results in increased expression of SNED1 mRNA CTD PMID:20436886 NCBI chr 9:100,380,487...100,439,125
Ensembl chr 9:100,380,515...100,437,056
JBrowse link
G Snx13 sorting nexin 13 decreases expression ISO Isotretinoin results in decreased expression of SNX13 mRNA CTD PMID:20436886 NCBI chr 6:54,487,626...54,591,716
Ensembl chr 6:54,488,038...54,588,778
JBrowse link
G Soat1 sterol O-acyltransferase 1 decreases expression ISO Isotretinoin results in decreased expression of SOAT1 mRNA CTD PMID:20436886 NCBI chr13:74,035,258...74,077,759
Ensembl chr13:74,035,080...74,077,783
JBrowse link
G Socs1 suppressor of cytokine signaling 1 decreases expression ISO Isotretinoin results in decreased expression of SOCS1 mRNA CTD PMID:15982314 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461
JBrowse link
G Socs2 suppressor of cytokine signaling 2 increases expression ISO Isotretinoin results in increased expression of SOCS2 mRNA CTD PMID:15982314 NCBI chr 7:36,495,496...36,500,878
Ensembl chr 7:36,495,480...36,499,784
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO Isotretinoin results in decreased expression of SOD2 mRNA CTD PMID:20436886 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 decreases expression ISO Isotretinoin results in decreased expression of SORBS1 mRNA CTD PMID:20436886 NCBI chr 1:259,373,921...259,502,108
Ensembl chr 1:259,376,933...259,484,569
JBrowse link
G Sord sorbitol dehydrogenase decreases expression ISO Isotretinoin results in decreased expression of SORD mRNA CTD PMID:20436886 NCBI chr 3:114,176,127...114,207,368
Ensembl chr 3:114,176,309...114,207,366
JBrowse link
G Sort1 sortilin 1 decreases expression ISO Isotretinoin results in decreased expression of SORT1 mRNA CTD PMID:20436886 NCBI chr 2:211,078,092...211,156,312
Ensembl chr 2:211,078,334...211,156,312
JBrowse link
G Sox17 SRY-box transcription factor 17 decreases localization ISO Isotretinoin results in decreased localization of SOX17 protein CTD PMID:24154490 NCBI chr 5:14,890,318...14,895,907
Ensembl chr 5:14,890,408...14,895,907
JBrowse link
G Spcs3 signal peptidase complex subunit 3 decreases expression ISO Isotretinoin results in decreased expression of SPCS3 mRNA CTD PMID:20436886 NCBI chr16:40,050,862...40,056,296
Ensembl chr16:40,050,734...40,058,822
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO Isotretinoin results in increased expression of SPP1 mRNA CTD PMID:18769122 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 increases expression ISO Isotretinoin results in increased expression of SPRED2 mRNA CTD PMID:20436886 NCBI chr14:104,268,362...104,290,206
Ensembl chr14:104,191,517...104,290,456
JBrowse link
G Sprr1b small proline-rich protein 1B increases expression ISO Isotretinoin results in increased expression of SPRR1B mRNA CTD PMID:15982314 NCBI chr 2:192,622,972...192,624,848
Ensembl chr 2:192,623,244...192,623,681
JBrowse link
G Sprr3 small proline-rich protein 3 decreases expression ISO Isotretinoin results in decreased expression of SPRR3 mRNA CTD PMID:18769122 NCBI chr 2:192,641,472...192,643,942
Ensembl chr 2:192,641,790...192,642,548
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases expression ISO Isotretinoin results in decreased expression of SRD5A1 mRNA CTD PMID:20436886 NCBI chr 1:36,320,504...36,354,694
Ensembl chr 1:36,320,461...36,354,756
JBrowse link
G Srpx2 sushi-repeat-containing protein, X-linked 2 decreases expression ISO Isotretinoin results in decreased expression of SRPX2 mRNA CTD PMID:20436886 NCBI chr  X:104,734,035...104,760,658
Ensembl chr  X:104,734,082...104,760,547
JBrowse link
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 decreases expression ISO Isotretinoin results in decreased expression of ST6GALNAC4 mRNA CTD PMID:20436886 NCBI chr 3:11,607,103...11,619,595
Ensembl chr 3:11,607,225...11,619,593
JBrowse link
G Stambp Stam binding protein decreases expression ISO Isotretinoin results in decreased expression of STAMBP mRNA CTD PMID:20436886 NCBI chr 4:115,249,343...115,277,340
Ensembl chr 4:115,249,351...115,275,068
JBrowse link
G Stap2 signal transducing adaptor family member 2 decreases expression ISO Isotretinoin results in decreased expression of STAP2 mRNA CTD PMID:20436886 NCBI chr 9:11,064,605...11,070,138
Ensembl chr 9:11,064,605...11,070,122
JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression ISO Isotretinoin results in decreased expression of STIP1 mRNA CTD PMID:18769122 NCBI chr 1:222,274,133...222,293,139
Ensembl chr 1:222,274,133...222,293,148
JBrowse link
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha decreases expression ISO Isotretinoin results in decreased expression of SUCLG1 mRNA CTD PMID:20436886 NCBI chr 4:101,181,315...101,210,692
Ensembl chr 4:101,180,404...101,210,746
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases expression ISO Isotretinoin results in increased expression of SULT2A1 mRNA CTD PMID:15982314 NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230
JBrowse link
G Susd5 sushi domain containing 5 increases expression ISO Isotretinoin results in increased expression of SUSD5 mRNA CTD PMID:20436886 NCBI chr 8:122,331,489...122,370,684
Ensembl chr 8:122,331,583...122,368,368
JBrowse link
G Syn2 synapsin II decreases expression ISO Isotretinoin results in decreased expression of SYN2 mRNA CTD PMID:20436886 NCBI chr 4:147,037,179...147,195,096
Ensembl chr 4:147,037,179...147,195,096
JBrowse link
G Syngr1 synaptogyrin 1 decreases expression ISO Isotretinoin results in decreased expression of SYNGR1 mRNA CTD PMID:20436886 NCBI chr 7:121,311,008...121,334,437
Ensembl chr 7:121,311,024...121,334,437
JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 increases expression ISO Isotretinoin results in increased expression of TACSTD2 mRNA CTD PMID:15982314 NCBI chr 4:98,341,187...98,342,887
Ensembl chr 4:98,341,188...98,342,887
JBrowse link
G Tagln transgelin increases expression
multiple interactions
ISO Isotretinoin results in increased expression of TAGLN mRNA
[LAQ824 co-treated with Isotretinoin] results in increased expression of TAGLN mRNA
CTD PMID:17237267 NCBI chr 8:50,222,895...50,228,369
Ensembl chr 8:50,222,896...50,231,357
JBrowse link
G Tagln3 transgelin 3 decreases expression ISO Isotretinoin results in decreased expression of TAGLN3 mRNA CTD PMID:20436886 NCBI chr11:60,072,983...60,086,552
Ensembl chr11:60,072,727...60,086,553
JBrowse link
G Taldo1 transaldolase 1 decreases expression ISO Isotretinoin results in decreased expression of TALDO1 mRNA CTD PMID:20436886 NCBI chr 1:214,375,555...214,385,886
Ensembl chr 1:214,375,515...214,385,885
JBrowse link
G Tbc1d1 TBC1 domain family member 1 increases expression ISO Isotretinoin results in increased expression of TBC1D1 mRNA CTD PMID:20436886 NCBI chr14:45,598,753...45,797,650
Ensembl chr14:45,598,743...45,797,887
JBrowse link
G Tbl1xr1 TBL1X receptor 1 increases expression ISO Isotretinoin results in increased expression of TBL1XR1 mRNA CTD PMID:20436886 NCBI chr 2:107,221,913...107,359,229
Ensembl chr 2:107,233,054...107,359,229
JBrowse link
G Tcf15 transcription factor 15 decreases expression ISO Isotretinoin results in decreased expression of TCF15 mRNA CTD PMID:31711903 NCBI chr 3:147,643,250...147,649,511
Ensembl chr 3:147,643,250...147,649,504
JBrowse link
G Tcta T-cell leukemia translocation altered decreases expression ISO Isotretinoin results in decreased expression of TCTA mRNA CTD PMID:20436886 NCBI chr 8:117,079,094...117,082,338
Ensembl chr 8:117,079,095...117,082,162
JBrowse link
G Tecr trans-2,3-enoyl-CoA reductase decreases expression ISO Isotretinoin results in decreased expression of TECR mRNA CTD PMID:20436886 NCBI chr19:24,705,478...24,732,024
Ensembl chr19:24,705,481...24,732,024
JBrowse link
G Tent5c terminal nucleotidyltransferase 5C decreases expression ISO Isotretinoin results in decreased expression of TENT5C mRNA CTD PMID:20436886 NCBI chr 2:202,797,766...202,816,562
Ensembl chr 2:202,798,198...202,816,562
JBrowse link
G Tert telomerase reverse transcriptase decreases expression ISO Isotretinoin results in decreased expression of TERT mRNA CTD PMID:16180984 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tfdp2 transcription factor Dp-2 decreases expression ISO Isotretinoin results in decreased expression of TFDP2 mRNA CTD PMID:20436886 NCBI chr 8:104,040,795...104,181,228
Ensembl chr 8:104,040,934...104,176,446
JBrowse link
G Tff2 trefoil factor 2 decreases expression ISO Isotretinoin results in decreased expression of TFF2 mRNA CTD PMID:20436886 NCBI chr20:9,872,669...9,876,008
Ensembl chr20:9,872,680...9,876,008
JBrowse link
G Tfrc transferrin receptor decreases expression ISO Isotretinoin results in decreased expression of TFRC mRNA CTD PMID:20436886 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression EXP Isotretinoin results in decreased expression of TGFB1 mRNA CTD PMID:15972972 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 increases expression ISO Isotretinoin results in increased expression of TGFB1I1 mRNA CTD PMID:15982314 NCBI chr 1:199,664,039...199,670,970
Ensembl chr 1:199,664,173...199,670,961
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 increases expression ISO Isotretinoin results in increased expression of TGFBR2 mRNA CTD PMID:20436886 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Tgm1 transglutaminase 1 decreases expression ISO Isotretinoin results in decreased expression of TGM1 mRNA CTD PMID:15982314 NCBI chr15:34,378,136...34,393,150
Ensembl chr15:34,378,148...34,392,066
JBrowse link
G Thbs1 thrombospondin 1 decreases expression ISO Isotretinoin results in decreased expression of THBS1 mRNA CTD PMID:15982314 PMID:18769122 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Thbs4 thrombospondin 4 increases expression ISO Isotretinoin results in increased expression of THBS4 mRNA CTD PMID:20436886 NCBI chr 2:22,343,727...22,385,855
Ensembl chr 2:22,343,727...22,385,855
JBrowse link
G Thra thyroid hormone receptor alpha decreases expression EXP Isotretinoin results in decreased expression of THRA mRNA CTD PMID:19041696 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link
G Thrb thyroid hormone receptor beta decreases expression EXP Isotretinoin results in decreased expression of THRB mRNA CTD PMID:19041696 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
G Timm13 translocase of inner mitochondrial membrane 13 decreases expression ISO Isotretinoin results in decreased expression of TIMM13 mRNA CTD PMID:20436886 NCBI chr 7:11,677,340...11,678,443
Ensembl chr 7:11,677,340...11,678,442
JBrowse link
G Timm23 translocase of inner mitochondrial membrane 23 decreases expression ISO Isotretinoin results in decreased expression of TIMM23 mRNA CTD PMID:20436886 NCBI chr16:8,324,038...8,350,067
Ensembl chr16:8,324,036...8,350,067
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 increases expression ISO Isotretinoin results in increased expression of TIMP3 mRNA CTD PMID:20436886 NCBI chr 7:23,543,125...23,594,170
Ensembl chr 7:23,544,215...23,594,133
JBrowse link
G Tjp3 tight junction protein 3 increases expression ISO Isotretinoin results in increased expression of TJP3 mRNA CTD PMID:18769122 NCBI chr 7:11,295,892...11,314,535
Ensembl chr 7:11,295,892...11,315,615
JBrowse link
G Tkt transketolase decreases expression ISO Isotretinoin results in decreased expression of TKT mRNA CTD PMID:20436886 NCBI chr16:6,609,670...6,634,608
Ensembl chr16:6,609,668...6,634,595
JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 decreases expression ISO Isotretinoin results in decreased expression of TM7SF2 mRNA CTD