Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:isotretinoin
go back to main search page
Accession:CHEBI:6067 term browser browse the term
Definition:A retinoic acid that is all-trans-retinoic acid in which the double bond which is alpha,beta- to the carboxy group is isomerised to Z configuration. A synthetic retinoid, it is used for the treatment of severe cases of acne and other skin diseases.
Synonyms:exact_synonym: (2Z,4E6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
 related_synonym: (7E,9E,11E,13Z)-retinoic acid;   13-RA;   13-cis-Vitamin A acid;   13-cis-retinoic acid;   Accutane;   Amnesteem;   Claravis;   Formula=C20H28O2;   InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14-;   InChIKey=SHGAZHPCJJPHSC-XFYACQKRSA-N;   Neovitamin A acid;   SMILES=CC(\\C=C\\C1=C(C)CCCC1(C)C)=C/C=C/C(C)=C\\C(O)=O;   cis-RA;   isotretinoina;   isotretinoine;   isotretinoino;   isotretinoinum
 xref: Beilstein:1885770;   CAS:4759-48-2;   DrugBank:DB00982;   Drug_Central:1508;   HMDB:HMDB0006219;   KEGG:D00348;   LIPID_MAPS_instance:LMPR01090021
 xref_mesh: MESH:D015474
 xref: PMID:11606947;   PMID:11866680;   PMID:15304471;   PMID:18077132;   PMID:18788179;   PMID:19568610;   PMID:20482692;   PMID:23676507;   PMID:9807973;   Patent:EP111325;   Patent:US4556518;   Reaxys:1885770;   Wikipedia:Isotretinoin

show annotations for term's descendants           Sort by:
 
isotretinoin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin increases expression ISO Isotretinoin results in increased expression of A2M mRNA CTD PMID:20436886 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137 		JBrowse link
G Aacs acetoacetyl-CoA synthetase decreases expression ISO Isotretinoin results in decreased expression of AACS mRNA CTD PMID:20436886 NCBI chr12:36,512,393...36,555,694
Ensembl chr12:36,512,393...36,555,694 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 increases expression EXP Isotretinoin results in increased expression of ABCA1 protein CTD PMID:17478430 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO [vorinostat co-treated with Isotretinoin] results in increased expression of ABCB1 mRNA CTD PMID:18769122 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 increases expression EXP Isotretinoin results in increased expression of ABCG1 protein CTD PMID:17478430 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489 		JBrowse link
G Abhd5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase decreases expression ISO Isotretinoin results in decreased expression of ABHD5 mRNA CTD PMID:20436886 NCBI chr 8:130,973,222...131,001,448
Ensembl chr 8:130,973,201...131,001,458 		JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A decreases expression ISO Isotretinoin results in decreased expression of ACAA1 mRNA CTD PMID:20436886 NCBI chr 8:128,027,880...128,036,471
Ensembl chr 8:128,027,958...128,036,236 		JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 decreases expression ISO Isotretinoin results in decreased expression of ACAA2 mRNA CTD PMID:20436886 NCBI chr18:70,733,872...70,762,395
Ensembl chr18:70,733,872...70,762,395 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases expression ISO Isotretinoin results in decreased expression of ACACA mRNA CTD PMID:20436886 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910 		JBrowse link
G Acad8 acyl-CoA dehydrogenase family, member 8 decreases expression ISO Isotretinoin results in decreased expression of ACAD8 mRNA CTD PMID:20436886 NCBI chr 8:28,023,401...28,044,967
Ensembl chr 8:28,024,123...28,044,876 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases expression ISO Isotretinoin results in decreased expression of ACADM mRNA CTD PMID:20436886 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589 		JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain decreases expression ISO Isotretinoin results in decreased expression of ACADVL mRNA CTD PMID:20436886 NCBI chr10:56,619,321...56,624,468
Ensembl chr10:56,619,303...56,624,526 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 decreases expression ISO Isotretinoin results in decreased expression of ACAT2 mRNA CTD PMID:20436886 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653 		JBrowse link
G Acly ATP citrate lyase decreases expression ISO Isotretinoin results in decreased expression of ACLY mRNA CTD PMID:20436886 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845 		JBrowse link
G Aco1 aconitase 1 decreases expression ISO Isotretinoin results in decreased expression of ACO1 mRNA CTD PMID:20436886 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218 		JBrowse link
G Acot13 acyl-CoA thioesterase 13 decreases expression ISO Isotretinoin results in decreased expression of ACOT13 mRNA CTD PMID:20436886 NCBI chr17:42,241,141...42,253,611
Ensembl chr17:42,241,159...42,253,649 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 decreases expression ISO Isotretinoin results in decreased expression of ACOT2 mRNA CTD PMID:20436886 NCBI chr 6:107,460,596...107,468,324
Ensembl chr 6:107,460,668...107,467,487 		JBrowse link
G Acox2 acyl-CoA oxidase 2 decreases expression ISO Isotretinoin results in decreased expression of ACOX2 mRNA CTD PMID:20436886 NCBI chr15:18,449,304...18,481,472
Ensembl chr15:18,451,144...18,481,470 		JBrowse link
G Acp6 acid phosphatase 6, lysophosphatidic decreases expression ISO Isotretinoin results in decreased expression of ACP6 mRNA CTD PMID:20436886 NCBI chr 2:199,284,177...199,305,793
Ensembl chr 2:199,283,909...199,305,799 		JBrowse link
G Acsbg1 acyl-CoA synthetase bubblegum family member 1 decreases expression ISO Isotretinoin results in decreased expression of ACSBG1 mRNA CTD PMID:20436886 NCBI chr 8:59,184,111...59,240,133
Ensembl chr 8:59,184,113...59,239,954 		JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression ISO Isotretinoin results in decreased expression of ACSL3 mRNA CTD PMID:20436886 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565 		JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression ISO Isotretinoin results in decreased expression of ACSL5 mRNA CTD PMID:20436886 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008 		JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 decreases expression ISO Isotretinoin results in decreased expression of SAH mRNA CTD PMID:20436886 NCBI chr 1:189,514,504...189,541,233
Ensembl chr 1:189,514,553...189,541,224 		JBrowse link
G Acy1 aminoacylase 1 decreases expression ISO Isotretinoin results in decreased expression of ACY1 mRNA CTD PMID:20436886 NCBI chr 8:115,134,792...115,140,171
Ensembl chr 8:115,134,765...115,140,080 		JBrowse link
G Adgra2 adhesion G protein-coupled receptor A2 increases expression ISO Isotretinoin results in increased expression of ADGRA2 mRNA CTD PMID:20436886 NCBI chr16:69,094,587...69,133,015
Ensembl chr16:69,095,936...69,132,584 		JBrowse link
G Adgre5 adhesion G protein-coupled receptor E5 increases expression ISO Isotretinoin results in increased expression of ADGRE5 mRNA CTD PMID:20436886 NCBI chr19:24,854,981...24,875,712
Ensembl chr19:24,855,299...24,875,137 		JBrowse link
G Adgrg2 adhesion G protein-coupled receptor G2 decreases expression ISO Isotretinoin results in decreased expression of ADGRG2 mRNA CTD PMID:20436886 NCBI chr  X:36,930,186...37,054,968
Ensembl chr  X:36,930,186...37,003,642 		JBrowse link
G Adra2a adrenoceptor alpha 2A increases expression ISO Isotretinoin results in increased expression of ADRA2A mRNA CTD PMID:20436886 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081 		JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein decreases expression ISO Isotretinoin results in decreased expression of ADTRP mRNA CTD PMID:20436886 NCBI chr17:22,619,913...22,688,296
Ensembl chr17:22,619,891...22,688,307 		JBrowse link
G Aga aspartylglucosaminidase decreases expression ISO Isotretinoin results in decreased expression of AGA mRNA CTD PMID:20436886 NCBI chr16:41,222,225...41,234,169
Ensembl chr16:41,222,238...41,234,095 		JBrowse link
G Agpat3 1-acylglycerol-3-phosphate O-acyltransferase 3 decreases expression ISO Isotretinoin results in decreased expression of AGPAT3 mRNA CTD PMID:20436886 NCBI chr20:11,060,584...11,144,806
Ensembl chr20:11,114,164...11,144,806 		JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member decreases expression ISO Isotretinoin results in decreased expression of AGR2 mRNA CTD PMID:20436886 NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression EXP Isotretinoin results in increased expression of AGTR1 mRNA; Isotretinoin results in increased expression of AGTR1 protein CTD PMID:19212007 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077 		JBrowse link
G Ahsp alpha hemoglobin stabilizing protein decreases expression ISO Isotretinoin results in decreased expression of AHSP mRNA CTD PMID:20436886 NCBI chr 1:199,720,038...199,721,010
Ensembl chr 1:199,720,038...199,721,010 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 decreases expression ISO Isotretinoin results in decreased expression of AIFM1 mRNA CTD PMID:20436886 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087 		JBrowse link
G Aip aryl-hydrocarbon receptor-interacting protein decreases expression ISO Isotretinoin results in decreased expression of AIP mRNA CTD PMID:15982314 NCBI chr 1:219,361,859...219,373,924
Ensembl chr 1:219,361,860...219,374,014 		JBrowse link
G Akap11 A-kinase anchoring protein 11 increases expression ISO Isotretinoin results in increased expression of AKAP11 mRNA CTD PMID:20436886 NCBI chr15:60,722,138...60,766,673
Ensembl chr15:60,722,160...60,766,579 		JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 decreases expression ISO Isotretinoin results in decreased expression of AKR1A1 mRNA CTD PMID:20436886 NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 decreases expression ISO Isotretinoin results in decreased expression of ALAS1 mRNA CTD PMID:20436886 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177 		JBrowse link
G Alb albumin decreases expression EXP Isotretinoin results in decreased expression of ALB protein CTD PMID:16092084 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863 		JBrowse link
G Alcam activated leukocyte cell adhesion molecule decreases expression ISO Isotretinoin results in decreased expression of ALCAM mRNA CTD PMID:20436886 NCBI chr11:50,780,735...50,985,083
Ensembl chr11:50,781,127...50,985,083 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases expression ISO Isotretinoin results in decreased expression of ALDH1A2 mRNA CTD PMID:31711903 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489 		JBrowse link
G Aldh3b2 aldehyde dehydrogenase 3 family, member B2 decreases expression ISO Isotretinoin results in decreased expression of ALDH3B2 mRNA CTD PMID:20436886 NCBI chr 1:219,215,023...219,218,488 JBrowse link
G Alg13 ALG13, UDP-N-acetylglucosaminyltransferase subunit decreases expression ISO Isotretinoin results in decreased expression of ALG13 mRNA CTD PMID:20436886 NCBI chr  X:115,561,329...115,589,792
Ensembl chr  X:115,561,332...115,619,505 		JBrowse link
G Alox15b arachidonate 15-lipoxygenase, type B decreases expression ISO Isotretinoin results in decreased expression of ALOX15B mRNA CTD PMID:20436886 NCBI chr10:55,773,748...55,783,489
Ensembl chr10:55,774,006...55,783,489 		JBrowse link
G Amacr alpha-methylacyl-CoA racemase decreases expression ISO Isotretinoin results in decreased expression of AMACR mRNA CTD PMID:20436886 NCBI chr 2:60,949,276...60,961,342
Ensembl chr 2:60,949,256...60,961,326 		JBrowse link
G Ank2 ankyrin 2 increases expression ISO Isotretinoin results in increased expression of ANK2 mRNA CTD PMID:20436886 NCBI chr 2:231,224,643...231,522,655
Ensembl chr 2:231,226,949...231,648,122 		JBrowse link
G Ankhd1 ankyrin repeat and KH domain containing 1 decreases expression ISO Isotretinoin results in decreased expression of ANKHD1 mRNA CTD PMID:20436886 NCBI chr18:29,386,906...29,485,611
Ensembl chr18:29,386,809...29,492,718 		JBrowse link
G Ano10 anoctamin 10 decreases expression ISO Isotretinoin results in decreased expression of ANO10 mRNA CTD PMID:20436886 NCBI chr 8:130,812,941...130,931,021
Ensembl chr 8:130,813,214...130,930,990 		JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 increases expression ISO Isotretinoin results in increased expression of AP2B1 mRNA CTD PMID:20436886 NCBI chr10:70,516,462...70,621,973
Ensembl chr10:70,520,206...70,621,977 		JBrowse link
G Ap3s2 adaptor related protein complex 3 subunit sigma 2 decreases expression ISO Isotretinoin results in decreased expression of AP3S2 mRNA CTD PMID:20436886 NCBI chr 1:141,612,961...141,655,417
Ensembl chr 1:141,612,963...141,655,894 		JBrowse link
G Apoc1 apolipoprotein C1 decreases expression ISO Isotretinoin results in decreased expression of APOC1 mRNA CTD PMID:20436886 NCBI chr 1:80,606,638...80,609,921
Ensembl chr 1:80,606,638...80,609,921 		JBrowse link
G Apoe apolipoprotein E affects response to substance ISO APOE gene polymorphism affects the susceptibility to Isotretinoin CTD PMID:12622636 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057 		JBrowse link
G Apool apolipoprotein O-like decreases expression ISO Isotretinoin results in decreased expression of APOOL mRNA CTD PMID:20436886 NCBI chr  X:83,678,269...83,750,550
Ensembl chr  X:83,678,339...83,750,549 		JBrowse link
G Areg amphiregulin multiple interactions ISO Isotretinoin inhibits the reaction [Calcitriol results in increased expression of AREG mRNA] CTD PMID:11237771 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179 		JBrowse link
G Arg2 arginase 2 decreases expression ISO Isotretinoin results in decreased expression of ARG2 mRNA CTD PMID:20436886 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520 		JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases expression ISO Isotretinoin results in increased expression of ARHGDIB mRNA CTD PMID:20436886 NCBI chr 4:170,913,920...170,932,789
Ensembl chr 4:170,913,923...170,932,618 		JBrowse link
G Arhgef6 Rac/Cdc42 guanine nucleotide exchange factor 6 increases expression ISO Isotretinoin results in increased expression of ARHGEF6 mRNA CTD PMID:20436886 NCBI chr  X:159,722,031...159,841,344
Ensembl chr  X:159,723,866...159,841,072 		JBrowse link
G Artn artemin multiple interactions ISO [vorinostat co-treated with Isotretinoin] results in increased expression of ARTN mRNA CTD PMID:18769122 NCBI chr 5:136,759,717...136,765,036
Ensembl chr 5:136,759,717...136,762,986 		JBrowse link
G Asap3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 increases expression ISO Isotretinoin results in increased expression of ASAP3 mRNA CTD PMID:20436886 NCBI chr 5:154,551,901...154,596,125
Ensembl chr 5:154,552,195...154,594,785 		JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO Isotretinoin affects the localization of and results in decreased activity of ATF2 protein CTD PMID:18652567 PMID:19066126 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951 		JBrowse link
G Atf5 activating transcription factor 5 multiple interactions ISO [vorinostat co-treated with Isotretinoin] results in decreased expression of ATF5 mRNA CTD PMID:18769122 NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522 		JBrowse link
G Atg4a autophagy related 4A, cysteine peptidase decreases expression ISO Isotretinoin results in decreased expression of ATG4A mRNA CTD PMID:20436886 NCBI chr  X:112,328,907...112,403,157 JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 increases expression ISO Isotretinoin results in increased expression of ATP2B4 mRNA CTD PMID:20436886 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823 		JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma decreases expression ISO Isotretinoin results in decreased expression of ATP5F1C mRNA CTD PMID:20436886 NCBI chr17:72,209,321...72,231,562
Ensembl chr17:72,209,373...72,394,271 		JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 decreases expression ISO Isotretinoin results in decreased expression of ATP5MC3 mRNA CTD PMID:20436886 NCBI chr 3:60,811,218...60,813,903
Ensembl chr 3:60,811,210...60,813,869 		JBrowse link
G Atp5mf ATP synthase membrane subunit f decreases expression ISO Isotretinoin results in decreased expression of ATP5MF mRNA CTD PMID:20436886 NCBI chr12:11,191,799...11,198,369
Ensembl chr12:11,191,812...11,198,369 		JBrowse link
G Atp5mj ATP synthase membrane subunit j decreases expression ISO Isotretinoin results in decreased expression of ATP5MJ mRNA CTD PMID:20436886
G Atp6v0b ATPase H+ transporting V0 subunit B decreases expression ISO Isotretinoin results in decreased expression of ATP6V0B mRNA CTD PMID:20436886 NCBI chr 5:136,718,352...136,719,868
Ensembl chr 5:136,718,352...136,721,379 		JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C decreases expression ISO Isotretinoin results in decreased expression of ATP6V0C mRNA CTD PMID:20436886 NCBI chr10:13,537,031...13,543,407
Ensembl chr10:13,537,033...13,542,077 		JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D decreases expression ISO Isotretinoin results in decreased expression of ATP6V1D mRNA CTD PMID:20436886 NCBI chr 6:102,032,271...102,047,754
Ensembl chr 6:102,032,276...102,047,758 		JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression ISO Isotretinoin results in increased expression of BASP1 mRNA CTD PMID:20436886 NCBI chr 2:77,586,424...77,632,626
Ensembl chr 2:77,586,424...77,632,628 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Isotretinoin results in increased expression of BAX; Isotretinoin results in increased expression of BAX protein CTD PMID:16109544 PMID:16135400 PMID:16909596 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcap29 B-cell receptor-associated protein 29 decreases expression ISO Isotretinoin results in decreased expression of BCAP29 mRNA CTD PMID:20436886 NCBI chr 6:50,883,758...50,923,743
Ensembl chr 6:50,883,787...50,923,510 		JBrowse link
G Bcap31 B-cell receptor-associated protein 31 decreases expression ISO Isotretinoin results in decreased expression of BCAP31 mRNA CTD PMID:20436886 NCBI chr  X:157,094,365...157,126,397
Ensembl chr  X:157,095,937...157,126,393 		JBrowse link
G Bcat2 branched chain amino acid transaminase 2 decreases expression ISO Isotretinoin results in decreased expression of BCAT2 mRNA CTD PMID:20436886 NCBI chr 1:101,553,900...101,572,103
Ensembl chr 1:101,554,642...101,572,080 		JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta decreases expression ISO Isotretinoin results in decreased expression of BCKDHB mRNA CTD PMID:20436886 NCBI chr 8:91,464,229...91,656,134
Ensembl chr 8:91,464,229...91,656,134 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
increases expression		 ISO Isotretinoin results in decreased expression of BCL2; Isotretinoin results in decreased expression of BCL2 protein
Isotretinoin results in decreased expression of BCL2; Isotretinoin results in decreased expression of BCL2 mRNA
Isotretinoin results in increased expression of BCL2 mRNA; Isotretinoin results in increased expression of BCL2 protein		 CTD PMID:16109544 PMID:16909596 PMID:18380168 PMID:18652567 PMID:21159604 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
decreases expression		 ISO Isotretinoin results in increased expression of BCL2L1 mRNA; Isotretinoin results in increased expression of BCL2L1 protein
Isotretinoin results in decreased expression of BCL2L1 protein		 CTD PMID:16135400 PMID:21159604 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810 		JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 decreases expression ISO Isotretinoin results in decreased expression of BDH1 mRNA CTD PMID:20436886 NCBI chr11:72,577,547...72,619,435
Ensembl chr11:72,578,533...72,614,176 		JBrowse link
G Bean1 brain expressed, associated with NEDD4, 1 decreases expression ISO Isotretinoin results in decreased expression of BEAN1 mRNA CTD PMID:20436886 NCBI chr19:947,862...993,467
Ensembl chr19:949,607...983,556 		JBrowse link
G Bend5 BEN domain containing 5 increases expression ISO Isotretinoin results in increased expression of BEND5 mRNA CTD PMID:20436886 NCBI chr 5:131,257,127...131,312,335
Ensembl chr 5:131,257,127...131,312,335 		JBrowse link
G Bgn biglycan increases expression ISO Isotretinoin results in increased expression of BGN mRNA CTD PMID:20436886 NCBI chr  X:157,319,042...157,331,204
Ensembl chr  X:157,319,046...157,331,204 		JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO Isotretinoin results in increased expression of BHLHE40 mRNA CTD PMID:18769122 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO Isotretinoin results in decreased expression of BIRC5 protein CTD PMID:16135400 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413 		JBrowse link
G Blvrb biliverdin reductase B decreases expression ISO Isotretinoin results in decreased expression of BLVRB mRNA CTD PMID:20436886 NCBI chr 1:84,256,063...84,273,726
Ensembl chr 1:84,256,159...84,274,075 		JBrowse link
G Bmerb1 bMERB domain containing 1 increases expression ISO Isotretinoin results in increased expression of BMERB1 mRNA CTD PMID:20436886 NCBI chr10:3,411,380...3,570,689
Ensembl chr10:3,411,380...3,570,688 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase decreases expression ISO Isotretinoin results in decreased expression of BRAF mRNA CTD PMID:20436886 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356 		JBrowse link
G Bsg basigin (Ok blood group) decreases expression ISO Isotretinoin results in decreased expression of BSG mRNA CTD PMID:20436886 NCBI chr 7:12,875,536...12,882,753
Ensembl chr 7:12,875,537...12,882,753 		JBrowse link
G Btbd3 BTB domain containing 3 increases expression ISO Isotretinoin results in increased expression of BTBD3 mRNA CTD PMID:20436886 NCBI chr 3:131,330,338...131,360,554
Ensembl chr 3:131,351,587...131,357,929 		JBrowse link
G Btd biotinidase decreases expression ISO Isotretinoin results in decreased expression of BTD mRNA CTD PMID:20436886 NCBI chr16:7,758,192...7,791,301
Ensembl chr16:7,758,996...7,791,243 		JBrowse link
G C1r complement C1r increases expression ISO Isotretinoin results in increased expression of C1R mRNA CTD PMID:20436886 NCBI chr 4:157,126,060...157,136,825
Ensembl chr 4:157,125,998...157,136,829 		JBrowse link
G C1s complement C1s increases expression ISO Isotretinoin results in increased expression of C1S mRNA CTD PMID:20436886 NCBI chr 4:157,143,592...157,155,592
Ensembl chr 4:157,143,592...157,155,609 		JBrowse link
G C3 complement C3 increases expression ISO Isotretinoin results in increased expression of C3 mRNA CTD PMID:20436886 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167 		JBrowse link
G Cald1 caldesmon 1 increases expression ISO Isotretinoin results in increased expression of CALD1 mRNA CTD PMID:20436886 NCBI chr 4:62,103,948...62,291,375
Ensembl chr 4:62,220,736...62,291,489 		JBrowse link
G Calml3 calmodulin-like 3 decreases expression ISO Isotretinoin results in decreased expression of CALML3 mRNA CTD PMID:20436886 NCBI chr17:70,070,458...70,073,697
Ensembl chr17:70,072,156...70,073,530 		JBrowse link
G Casp3 caspase 3 increases cleavage
increases expression		 ISO Isotretinoin results in increased cleavage of CASP3 protein
Isotretinoin results in increased expression of CASP3; Isotretinoin results in increased expression of CASP3 mRNA
Isotretinoin results in increased expression of CASP3; Isotretinoin results in increased expression of CASP3 protein		 CTD PMID:16109544 PMID:16135400 PMID:16157052 PMID:16575387 PMID:16909596 PMID:18380168 PMID:18652567 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp8 caspase 8 increases cleavage ISO Isotretinoin results in increased cleavage of CASP8 protein CTD PMID:16135400 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106 		JBrowse link
G Cat catalase multiple interactions ISO Isotretinoin inhibits the reaction [Benzoyl Peroxide results in decreased activity of CAT protein] CTD PMID:15225900 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Cavin1 caveolae associated protein 1 increases expression ISO Isotretinoin results in increased expression of CAVIN1 mRNA CTD PMID:20436886 NCBI chr10:88,862,513...88,874,495
Ensembl chr10:88,860,733...88,874,528 		JBrowse link
G Cbx3 chromobox 3 decreases expression ISO Isotretinoin results in decreased expression of CBX3 mRNA CTD PMID:15982314 NCBI chr 4:81,243,809...81,257,898
Ensembl chr 4:81,244,469...81,257,897 		JBrowse link
G Ccdc86 coiled-coil domain containing 86 decreases expression ISO Isotretinoin results in decreased expression of CCDC86 mRNA CTD PMID:20436886 NCBI chr 1:226,996,435...227,002,016
Ensembl chr 1:226,996,237...227,002,139 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression EXP Isotretinoin results in decreased expression of CCL2 mRNA CTD PMID:15972972 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression EXP Isotretinoin results in decreased expression of CCL3 mRNA CTD PMID:15972972 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions
decreases expression		 ISO
EXP		 Isotretinoin inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; Isotretinoin inhibits the reaction [TNF protein results in increased secretion of CCL5 protein]
Isotretinoin results in decreased expression of CCL5 mRNA		 CTD PMID:15972972 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Isotretinoin results in decreased expression of CCND1 protein CTD PMID:16575387 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325 		JBrowse link
G Cd2 Cd2 molecule increases expression ISO Isotretinoin results in increased expression of CD2 mRNA CTD PMID:20436886 NCBI chr 2:203,666,706...203,680,073
Ensembl chr 2:203,666,637...203,680,083 		JBrowse link
G Cd247 Cd247 molecule increases expression ISO Isotretinoin results in increased expression of CD3Z mRNA CTD PMID:20436886 NCBI chr13:83,996,045...84,071,408
Ensembl chr13:83,996,080...84,071,400 		JBrowse link
G Cd34 CD34 molecule increases expression ISO Isotretinoin results in increased expression of CD34 mRNA CTD PMID:20436886 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647 		JBrowse link
G Cd37 CD37 molecule increases expression ISO Isotretinoin results in increased expression of CD37 mRNA CTD PMID:20436886 NCBI chr 1:101,230,470...101,236,061
Ensembl chr 1:101,230,533...101,236,065 		JBrowse link
G Cd38 CD38 molecule increases expression ISO Isotretinoin results in increased expression of CD38 protein CTD PMID:16275619 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672 		JBrowse link
G Cd3d CD3d molecule increases expression ISO Isotretinoin results in increased expression of CD3D mRNA CTD PMID:20436886 NCBI chr 8:49,282,502...49,287,095
Ensembl chr 8:49,282,460...49,287,110 		JBrowse link
G Cd52 CD52 molecule increases expression ISO Isotretinoin results in increased expression of CD52 mRNA CTD PMID:20436886 NCBI chr 5:152,322,910...152,324,469
Ensembl chr 5:152,322,916...152,324,469 		JBrowse link
G Cd69 Cd69 molecule multiple interactions ISO [Dacarbazine co-treated with Isotretinoin] affects the reaction [IFNA2 protein results in increased expression of CD69 protein] CTD PMID:17973783 NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084 		JBrowse link
G Cd81 Cd81 molecule increases expression ISO Isotretinoin results in increased expression of CD81 mRNA CTD PMID:20436886 NCBI chr 1:216,237,663...216,253,460
Ensembl chr 1:216,237,697...216,253,311 		JBrowse link
G Cda cytidine deaminase decreases expression ISO Isotretinoin results in decreased expression of CDA mRNA CTD PMID:20436886 NCBI chr 5:156,703,579...156,734,541
Ensembl chr 5:156,703,579...156,734,541 		JBrowse link
G Cdc14b cell division cycle 14B increases expression ISO Isotretinoin results in increased expression of CDC14B mRNA CTD PMID:20436886 NCBI chr17:1,709,703...1,797,732
Ensembl chr17:1,703,943...1,797,750 		JBrowse link
G Cdh5 cadherin 5 increases expression ISO Isotretinoin results in increased expression of CDH5 mRNA CTD PMID:18769122 NCBI chr19:1,025,122...1,074,333
Ensembl chr19:1,023,683...1,074,365 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 decreases expression ISO Isotretinoin results in decreased expression of CDK5 mRNA CTD PMID:20436886 NCBI chr 4:7,282,945...7,287,427
Ensembl chr 4:7,282,948...7,288,383 		JBrowse link
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 decreases expression ISO Isotretinoin results in decreased expression of CDK5RAP1 mRNA CTD PMID:20436886 NCBI chr 3:149,835,953...149,870,429
Ensembl chr 3:149,703,848...149,870,413 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression
multiple interactions
increases expression		 ISO Isotretinoin results in decreased expression of CDKN1A mRNA
[LAQ824 co-treated with Isotretinoin] results in increased expression of CDKN1A mRNA; [LAQ824 co-treated with Isotretinoin] results in increased expression of CDKN1A protein
Isotretinoin results in increased expression of CDKN1A protein		 CTD PMID:16575387 PMID:17237267 PMID:20436886 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression ISO Isotretinoin results in decreased expression of CDKN1C mRNA CTD PMID:15982314 NCBI chr 1:216,661,067...216,663,791
Ensembl chr 1:216,661,080...216,663,721 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 decreases expression ISO Isotretinoin results in decreased expression of CEACAM1 mRNA CTD PMID:20436886 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345 		JBrowse link
G Cel carboxyl ester lipase increases expression ISO Isotretinoin results in increased expression of CEL mRNA CTD PMID:18769122 NCBI chr 3:7,134,021...7,141,522
Ensembl chr 3:7,134,021...7,141,522 		JBrowse link
G Celf2 CUGBP, Elav-like family member 2 increases expression ISO Isotretinoin results in increased expression of CELF2 mRNA CTD PMID:20436886 NCBI chr17:75,259,269...75,660,154
Ensembl chr17:75,352,389...75,654,951 		JBrowse link
G Cers4 ceramide synthase 4 decreases expression ISO Isotretinoin results in decreased expression of CERS4 mRNA CTD PMID:20436886 NCBI chr12:4,439,750...4,474,759
Ensembl chr12:4,439,750...4,474,729 		JBrowse link
G Cfap45 cilia and flagella associated protein 45 decreases expression ISO Isotretinoin results in decreased expression of CFAP45 mRNA CTD PMID:20436886 NCBI chr13:90,909,551...90,932,958
Ensembl chr13:90,909,486...90,932,961 		JBrowse link
G Chi3l1 chitinase 3 like 1 decreases expression ISO Isotretinoin results in decreased expression of CHI3L1 mRNA CTD PMID:20436886 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802 		JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 decreases expression ISO Isotretinoin results in decreased expression of CHP1 mRNA CTD PMID:20436886 NCBI chr 3:111,354,506...111,389,998
Ensembl chr 3:111,354,506...111,389,989 		JBrowse link
G Chst5 carbohydrate sulfotransferase 5 increases expression ISO Isotretinoin results in increased expression of CHST6 mRNA CTD PMID:20436886 NCBI chr19:44,115,065...44,136,092
Ensembl chr19:44,115,120...44,135,387 		JBrowse link
G Cidea cell death-inducing DFFA-like effector a decreases expression ISO Isotretinoin results in decreased expression of CIDEA mRNA CTD PMID:20436886 NCBI chr18:63,082,861...63,108,450
Ensembl chr18:63,098,144...63,108,051 		JBrowse link
G Ckb creatine kinase B decreases expression ISO Isotretinoin results in decreased expression of CKB mRNA CTD PMID:15982314 NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837 		JBrowse link
G Ckm creatine kinase, M-type increases expression ISO Isotretinoin results in increased expression of CKM protein CTD PMID:9747221 NCBI chr 1:80,321,507...80,331,841
Ensembl chr 1:80,321,585...80,331,841 		JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1 decreases expression ISO Isotretinoin results in decreased expression of CKMT1 mRNA CTD PMID:20436886 NCBI chr 3:113,318,559...113,324,459
Ensembl chr 3:113,318,563...113,324,461 		JBrowse link
G Clcn3 chloride voltage-gated channel 3 decreases expression ISO Isotretinoin results in decreased expression of CLCN3 mRNA CTD PMID:20436886 NCBI chr16:32,448,821...32,520,649
Ensembl chr16:32,449,116...32,519,148 		JBrowse link
G Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit X decreases expression ISO Isotretinoin results in decreased expression of CLPX mRNA CTD PMID:20436886 NCBI chr 8:70,789,137...70,843,133
Ensembl chr 8:70,789,256...70,843,123 		JBrowse link
G Clstn3 calsyntenin 3 decreases expression ISO Isotretinoin results in decreased expression of CLSTN3 mRNA CTD PMID:20436886 NCBI chr 4:157,044,736...157,078,013
Ensembl chr 4:157,043,925...157,078,130 		JBrowse link
G Cndp2 carnosine dipeptidase 2 decreases expression ISO Isotretinoin results in decreased expression of CNDP2 mRNA CTD PMID:20436886 NCBI chr18:81,521,966...81,539,065
Ensembl chr18:81,521,968...81,539,065 		JBrowse link
G Coch cochlin increases expression ISO Isotretinoin results in increased expression of COCH mRNA CTD PMID:20436886 NCBI chr 6:72,359,702...72,373,710
Ensembl chr 6:72,359,791...72,373,695 		JBrowse link
G Col14a1 collagen type XIV alpha 1 chain increases expression ISO Isotretinoin results in increased expression of COL14A1 mRNA CTD PMID:20436886 NCBI chr 7:95,054,877...95,274,073
Ensembl chr 7:95,074,236...95,273,298 		JBrowse link
G Col17a1 collagen type XVII alpha 1 chain decreases expression ISO Isotretinoin results in decreased expression of COL17A1 mRNA CTD PMID:15982314 NCBI chr 1:267,416,681...267,465,049
Ensembl chr 1:267,417,459...267,463,705 		JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression EXP Isotretinoin results in decreased expression of COL1A1 mRNA; Isotretinoin results in decreased expression of COL1A1 protein CTD PMID:15972972 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789 		JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression EXP Isotretinoin results in decreased expression of COL3A1 mRNA; Isotretinoin results in decreased expression of COL3A1 protein CTD PMID:15972972 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217 		JBrowse link
G Col4a2 collagen type IV alpha 2 chain increases expression ISO Isotretinoin results in increased expression of COL4A2 mRNA CTD PMID:20436886 NCBI chr16:83,386,388...83,522,169
Ensembl chr16:83,387,364...83,438,561 		JBrowse link
G Col5a1 collagen type V alpha 1 chain increases expression ISO Isotretinoin results in increased expression of COL5A1 mRNA CTD PMID:20436886 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882 		JBrowse link
G Col5a2 collagen type V alpha 2 chain increases expression ISO Isotretinoin results in increased expression of COL5A2 mRNA CTD PMID:20436886 NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain decreases expression
increases expression		 ISO Isotretinoin results in decreased expression of COL6A1 mRNA
Isotretinoin results in increased expression of COL6A1 mRNA		 CTD PMID:15982314 PMID:20436886 NCBI chr20:12,657,913...12,676,370
Ensembl chr20:12,658,065...12,675,561 		JBrowse link
G Col6a2 collagen type VI alpha 2 chain increases expression ISO Isotretinoin results in increased expression of COL6A2 mRNA CTD PMID:20436886 NCBI chr20:12,773,472...12,801,179
Ensembl chr20:12,773,427...12,801,180 		JBrowse link
G Col6a3 collagen type VI alpha 3 chain increases expression ISO Isotretinoin results in increased expression of COL6A3 mRNA CTD PMID:20436886 NCBI chr 9:97,926,784...98,004,643
Ensembl chr 9:97,926,787...98,004,546 		JBrowse link
G Col8a2 collagen type VIII alpha 2 chain decreases expression ISO Isotretinoin results in decreased expression of COL8A2 mRNA CTD PMID:15982314 NCBI chr 5:144,308,527...144,335,142
Ensembl chr 5:144,308,611...144,335,172 		JBrowse link
G Cox5a cytochrome c oxidase subunit 5A decreases expression ISO Isotretinoin results in decreased expression of COX5A mRNA CTD PMID:20436886 NCBI chr 8:62,298,358...62,309,765
Ensembl chr 8:62,298,358...62,309,765 		JBrowse link
G Cox5b cytochrome c oxidase subunit 5B decreases expression ISO Isotretinoin results in decreased expression of COX5B mRNA CTD PMID:20436886 NCBI chr 9:43,259,706...43,262,039
Ensembl chr 9:43,259,709...43,262,040 		JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 decreases expression ISO Isotretinoin results in decreased expression of COX6A1 mRNA CTD PMID:20436886 NCBI chr12:47,024,442...47,027,495
Ensembl chr12:47,024,442...47,027,495 		JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 decreases expression ISO Isotretinoin results in decreased expression of COX7A2 mRNA CTD PMID:20436886 NCBI chr 8:87,209,529...87,213,627
Ensembl chr 8:87,209,530...87,213,627 		JBrowse link
G Cox7b cytochrome c oxidase subunit 7B decreases expression ISO Isotretinoin results in decreased expression of COX7B mRNA CTD PMID:20436886 NCBI chr  X:77,065,427...77,071,676
Ensembl chr  X:77,065,397...77,071,676 		JBrowse link
G Cpd carboxypeptidase D decreases expression ISO Isotretinoin results in decreased expression of CPD mRNA CTD PMID:20436886 NCBI chr10:63,325,764...63,389,811
Ensembl chr10:63,325,199...63,389,817 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 decreases expression ISO Isotretinoin results in decreased expression of CPT2 mRNA CTD PMID:20436886 NCBI chr 5:127,505,646...127,523,016
Ensembl chr 5:127,505,614...127,523,089 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression
multiple interactions		 ISO Isotretinoin results in increased expression of CRABP2 mRNA
R116010 promotes the reaction [Isotretinoin results in increased expression of CRABP2 mRNA]		 CTD PMID:17486130 NCBI chr 2:187,322,416...187,326,794
Ensembl chr 2:184,882,969...184,883,505 		JBrowse link
G Crat carnitine O-acetyltransferase decreases expression ISO Isotretinoin results in decreased expression of CRAT mRNA CTD PMID:20436886 NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation ISO Isotretinoin results in increased phosphorylation of CREB1 protein CTD PMID:16280361 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435 		JBrowse link
G Cript CXXC repeat containing interactor of PDZ3 domain decreases expression ISO Isotretinoin results in decreased expression of CRIPT mRNA CTD PMID:20436886 NCBI chr 6:10,594,147...10,602,103
Ensembl chr 6:10,594,122...10,602,085 		JBrowse link
G Crtc3 CREB regulated transcription coactivator 3 increases expression ISO Isotretinoin results in increased expression of CRTC3 mRNA CTD PMID:20436886 NCBI chr 1:142,398,248...142,500,562
Ensembl chr 1:142,393,207...142,500,383 		JBrowse link
G Cryz crystallin zeta multiple interactions ISO Isotretinoin inhibits the reaction [Benzoyl Peroxide results in decreased activity of CRYZ protein] CTD PMID:15225900 NCBI chr 2:260,884,315...260,911,827
Ensembl chr 2:260,884,337...260,911,792 		JBrowse link
G Csf1r colony stimulating factor 1 receptor increases expression ISO Isotretinoin results in increased expression of CSF1R mRNA CTD PMID:20436886 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300 		JBrowse link
G Csf2 colony stimulating factor 2 decreases secretion EXP Isotretinoin results in decreased secretion of CSF2 protein CTD PMID:15972972 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070 		JBrowse link
G Cst3 cystatin C increases expression ISO Isotretinoin results in increased expression of CST3 mRNA CTD PMID:20436886 NCBI chr 3:143,219,671...143,223,544
Ensembl chr 3:143,219,686...143,223,615 		JBrowse link
G Cstb cystatin B decreases expression ISO Isotretinoin results in decreased expression of CSTB mRNA CTD PMID:20436886 NCBI chr20:10,966,357...10,968,399
Ensembl chr20:10,966,331...10,968,432 		JBrowse link
G Cth cystathionine gamma-lyase decreases expression ISO Isotretinoin results in decreased expression of CTH mRNA CTD PMID:20436886 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046 		JBrowse link
G Cttn cortactin decreases expression ISO Isotretinoin results in decreased expression of CTTN mRNA CTD PMID:20436886 NCBI chr 1:217,602,698...217,638,196
NCBI chr 1:215,255,385...215,290,882
Ensembl chr 1:217,602,698...217,638,152
Ensembl chr 1:217,602,698...217,638,152 		JBrowse link
G Cux2 cut-like homeobox 2 decreases expression ISO Isotretinoin results in decreased expression of CUX2 mRNA CTD PMID:20436886 NCBI chr12:40,016,774...40,221,067
Ensembl chr12:40,018,937...40,219,291 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 decreases expression ISO Isotretinoin results in decreased expression of CXCL1 mRNA CTD PMID:15982314 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression ISO
EXP		 Isotretinoin results in decreased expression of CXCL10 mRNA CTD PMID:15972972 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO Isotretinoin results in increased expression of CXCL12 mRNA CTD PMID:20436886 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression ISO Isotretinoin results in decreased expression of CXCL1 mRNA CTD PMID:15982314 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595 		JBrowse link
G Cyb5a cytochrome b5 type A decreases expression ISO Isotretinoin results in decreased expression of CYB5A mRNA CTD PMID:20436886 NCBI chr18:81,694,818...81,726,821
Ensembl chr18:81,694,808...81,726,821 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression ISO Isotretinoin results in increased expression of CYP26A1 mRNA CTD PMID:16194896 PMID:17486130 PMID:18769122 NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 multiple interactions
increases expression		 ISO R116010 promotes the reaction [Isotretinoin results in increased expression of CYP26B1 mRNA] CTD PMID:17486130 PMID:18769122 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression ISO Isotretinoin results in decreased expression of CYP27A1 mRNA CTD PMID:15982314 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169 		JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 increases activity
multiple interactions		 ISO Isotretinoin results in increased activity of CYP3A4 protein
[Isotretinoin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; Isotretinoin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]		 CTD PMID:16632523 PMID:25455453 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397 		JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 decreases expression ISO Isotretinoin results in decreased expression of CYP4F3 mRNA CTD PMID:20436886 NCBI chr16:19,501,680...19,528,935
Ensembl chr16:19,410,810...19,528,999 		JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 decreases expression ISO Isotretinoin results in decreased expression of CYP4F8 mRNA CTD PMID:20436886 NCBI chr 7:15,198,950...15,225,547
Ensembl chr 7:15,198,940...15,225,410 		JBrowse link
G Cyp51 cytochrome P450, family 51 decreases expression ISO Isotretinoin results in decreased expression of CYP51A1 mRNA CTD PMID:20436886 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018 		JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein decreases expression ISO Isotretinoin results in decreased expression of DBI mRNA CTD PMID:20436886 NCBI chr13:36,147,667...36,156,076
Ensembl chr13:36,117,119...36,174,908 		JBrowse link
G Dbn1 drebrin 1 increases expression ISO Isotretinoin results in increased expression of DBN1 mRNA CTD PMID:20436886 NCBI chr17:9,679,511...9,693,878
Ensembl chr17:9,679,628...9,693,820 		JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 decreases expression ISO Isotretinoin results in decreased expression of DBT mRNA CTD PMID:20436886 NCBI chr 2:219,563,783...219,592,651
Ensembl chr 2:219,563,783...219,592,650 		JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase decreases expression ISO Isotretinoin results in decreased expression of DCXR mRNA CTD PMID:20436886 NCBI chr10:109,906,119...109,909,696
Ensembl chr10:109,906,815...109,909,715 		JBrowse link
G Ddc dopa decarboxylase decreases expression ISO Isotretinoin results in decreased expression of DDC mRNA CTD PMID:20436886 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774 		JBrowse link
G Ddo D-aspartate oxidase decreases expression ISO Isotretinoin results in decreased expression of DDO mRNA CTD PMID:20436886 NCBI chr20:48,739,812...48,758,958
Ensembl chr20:48,739,639...48,758,905 		JBrowse link
G Ddt D-dopachrome tautomerase decreases expression ISO Isotretinoin results in decreased expression of DDT mRNA CTD PMID:20436886 NCBI chr20:13,827,153...13,829,624
Ensembl chr20:13,827,132...13,831,588 		JBrowse link
G Dennd5a DENN domain containing 5A increases expression ISO Isotretinoin results in increased expression of DENND5A mRNA CTD PMID:20436886 NCBI chr 1:174,524,047...174,588,553
Ensembl chr 1:174,524,047...174,588,529 		JBrowse link
G Desi1 desumoylating isopeptidase 1 decreases expression ISO Isotretinoin results in decreased expression of DESI1 mRNA CTD PMID:20436886 NCBI chr 7:123,238,332...123,259,636
Ensembl chr 7:123,238,333...123,259,636 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO Isotretinoin results in decreased expression of DHCR24 mRNA CTD PMID:20436886 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression ISO Isotretinoin results in decreased expression of DHCR7 mRNA CTD PMID:20436886 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904 		JBrowse link
G Dhfr dihydrofolate reductase decreases expression ISO Isotretinoin results in decreased expression of DHFR mRNA CTD PMID:20436886 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453 		JBrowse link
G Dhrs11 dehydrogenase/reductase 11 decreases expression ISO Isotretinoin results in decreased expression of DHRS11 mRNA CTD PMID:20436886 NCBI chr10:72,144,042...72,153,496
Ensembl chr10:72,144,042...72,153,375 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases expression ISO Isotretinoin results in increased expression of DHRS3 mRNA CTD PMID:18769122 NCBI chr 5:162,809,090...162,843,385
Ensembl chr 5:162,808,646...162,843,383 		JBrowse link
G Dhrs7b dehydrogenase/reductase 7B decreases expression ISO Isotretinoin results in decreased expression of DHRS7B mRNA CTD PMID:20436886 NCBI chr10:47,065,755...47,111,089
Ensembl chr10:47,065,850...47,111,101 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 multiple interactions
decreases expression		 ISO [vorinostat co-treated with Isotretinoin] results in increased expression of DHRS9 mRNA
Isotretinoin results in decreased expression of DHRS9 mRNA		 CTD PMID:18769122 PMID:20436886 NCBI chr 3:55,623,671...55,645,883
Ensembl chr 3:55,623,634...55,648,325 		JBrowse link
G Diras3 DIRAS family GTPase 3 decreases expression ISO Isotretinoin results in decreased expression of DIRAS3 mRNA CTD PMID:20436886 NCBI chr 6:135,938,345...135,940,205
Ensembl chr 6:135,938,935...135,939,534 		JBrowse link
G Dixdc1 DIX domain containing 1 increases expression ISO Isotretinoin results in increased expression of DIXDC1 mRNA CTD PMID:20436886 NCBI chr 8:55,091,232...55,164,636
Ensembl chr 8:55,091,235...55,162,421 		JBrowse link
G Dld dihydrolipoamide dehydrogenase decreases expression ISO Isotretinoin results in decreased expression of DLD mRNA CTD PMID:20436886 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694 		JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 increases expression ISO Isotretinoin results in increased expression of DLG5 mRNA CTD PMID:20436886 NCBI chr15:120,213...230,312
Ensembl chr15:120,372...228,977 		JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase increases expression ISO Isotretinoin results in increased expression of DLST protein CTD PMID:15982314 NCBI chr 6:108,936,534...108,961,322
Ensembl chr 6:108,936,664...108,959,803 		JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 decreases expression ISO Isotretinoin results in decreased expression of DNAJA3 mRNA CTD PMID:20436886 NCBI chr10:11,059,701...11,085,186
Ensembl chr10:11,060,313...11,085,210 		JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 decreases expression ISO Isotretinoin results in decreased expression of DNAJC15 mRNA CTD PMID:20436886 NCBI chr15:59,990,131...60,056,710
Ensembl chr15:59,990,131...60,056,710 		JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 decreases expression ISO Isotretinoin results in decreased expression of DNAJC3 mRNA CTD PMID:20436886 NCBI chr15:104,186,918...104,226,236
Ensembl chr15:104,186,792...104,226,329 		JBrowse link
G Dnase1 deoxyribonuclease 1 increases expression ISO Isotretinoin results in increased expression of DNASE1 protein CTD PMID:15982314 NCBI chr10:11,757,681...11,760,672
Ensembl chr10:11,757,682...11,760,620 		JBrowse link
G Dnase1l2 deoxyribonuclease 1 like 2 decreases expression ISO Isotretinoin results in decreased expression of DNASE1L2 mRNA CTD PMID:20436886 NCBI chr10:13,812,335...13,814,514
Ensembl chr10:13,812,707...13,814,304 		JBrowse link
G Dnm1 dynamin 1 increases expression ISO Isotretinoin results in increased expression of DNM1 mRNA CTD PMID:20436886 NCBI chr 3:11,338,081...11,382,043
Ensembl chr 3:11,338,083...11,382,043 		JBrowse link
G Dop1b DOP1 leucine zipper like protein B decreases expression ISO Isotretinoin results in decreased expression of DOP1B mRNA CTD PMID:20436886 NCBI chr11:33,929,142...34,027,447
Ensembl chr11:33,925,498...34,027,435 		JBrowse link
G Dpp3 dipeptidylpeptidase 3 decreases expression ISO Isotretinoin results in decreased expression of DPP3 mRNA CTD PMID:20436886 NCBI chr 1:220,166,124...220,189,762
Ensembl chr 1:220,166,127...220,188,541 		JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 increases expression ISO Isotretinoin results in increased expression of DPYSL2 mRNA CTD PMID:20436886 NCBI chr15:43,475,640...43,581,725
Ensembl chr15:43,477,629...43,542,939 		JBrowse link
G Drp2 dystrophin related protein 2 decreases expression ISO Isotretinoin results in decreased expression of DRP2 mRNA CTD PMID:20436886 NCBI chr  X:105,239,623...105,290,233
Ensembl chr  X:105,239,620...105,289,808 		JBrowse link
G Dsc1 desmocollin 1 decreases expression ISO Isotretinoin results in decreased expression of DSC1 mRNA CTD PMID:15982314 NCBI chr18:11,877,918...11,906,828
Ensembl chr18:11,877,561...11,906,827 		JBrowse link
G Dsc2 desmocollin 2 decreases expression ISO Isotretinoin results in decreased expression of DSC2 mRNA CTD PMID:20436886 NCBI chr18:11,826,705...11,858,801
Ensembl chr18:11,826,706...11,858,754 		JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO Isotretinoin results in increased expression of DUSP10 mRNA CTD PMID:15982314 NCBI chr13:104,284,660...104,321,455
Ensembl chr13:104,284,660...104,321,455 		JBrowse link
G Dusp11 dual specificity phosphatase 11 decreases expression ISO Isotretinoin results in decreased expression of DUSP11 mRNA CTD PMID:15982314 NCBI chr 4:117,617,640...117,631,674
Ensembl chr 4:117,617,533...117,631,716 		JBrowse link
G Dusp4 dual specificity phosphatase 4 decreases expression ISO Isotretinoin results in decreased expression of DUSP4 mRNA CTD PMID:20436886 NCBI chr16:61,080,767...61,090,973
Ensembl chr16:61,078,175...61,091,169 		JBrowse link
G E2f8 E2F transcription factor 8 decreases expression ISO Isotretinoin results in decreased expression of E2F8 mRNA CTD PMID:20436886 NCBI chr 1:104,185,436...104,203,683
Ensembl chr 1:104,187,100...104,202,591 		JBrowse link
G Ebp EBP, cholestenol delta-isomerase decreases expression ISO Isotretinoin results in decreased expression of EBP mRNA CTD PMID:20436886 NCBI chr  X:15,049,394...15,055,782
Ensembl chr  X:15,049,462...15,055,781 		JBrowse link
G Ech1 enoyl-CoA hydratase 1 decreases expression ISO Isotretinoin results in decreased expression of ECH1 mRNA CTD PMID:20436886 NCBI chr 1:87,009,798...87,015,996
Ensembl chr 1:87,009,730...87,016,005 		JBrowse link
G Echdc1 ethylmalonyl-CoA decarboxylase 1 decreases expression ISO Isotretinoin results in decreased expression of ECHDC1 mRNA CTD PMID:20436886 NCBI chr 1:30,874,410...30,921,117
Ensembl chr 1:30,874,418...30,917,882 		JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 decreases expression ISO Isotretinoin results in decreased expression of ECI1 mRNA CTD PMID:20436886 NCBI chr10:13,797,573...13,810,918
Ensembl chr10:13,797,562...13,810,913 		JBrowse link
G Efemp2 EGF containing fibulin extracellular matrix protein 2 increases expression ISO Isotretinoin results in increased expression of EFEMP2 mRNA CTD PMID:20436886 NCBI chr 1:220,853,695...220,861,420
Ensembl chr 1:220,854,403...220,861,420 		JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO Isotretinoin results in decreased expression of EGFR mRNA CTD PMID:15982314 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796 		JBrowse link
G Egr3 early growth response 3 decreases expression ISO Isotretinoin results in decreased expression of EGR3 mRNA CTD PMID:20436886 NCBI chr15:51,756,683...51,762,080
Ensembl chr15:51,756,736...51,760,722 		JBrowse link
G Ei24 EI24, autophagy associated transmembrane protein decreases expression ISO Isotretinoin results in decreased expression of EI24 mRNA CTD PMID:20436886 NCBI chr 8:39,254,883...39,271,238
Ensembl chr 8:39,254,889...39,266,959 		JBrowse link
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma decreases expression ISO Isotretinoin results in decreased expression of EIF2B3 mRNA CTD PMID:20436886 NCBI chr 5:135,882,946...135,949,276
Ensembl chr 5:135,882,967...135,949,818 		JBrowse link
G Eif4e eukaryotic translation initiation factor 4E decreases expression ISO Isotretinoin results in decreased expression of EIF4E mRNA CTD PMID:20436886 NCBI chr 2:243,819,616...243,853,987
Ensembl chr 2:243,820,661...243,852,631 		JBrowse link
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 decreases expression ISO Isotretinoin results in decreased expression of EIF4EBP2 mRNA CTD PMID:15982314 NCBI chr20:31,055,292...31,072,469
Ensembl chr20:31,055,789...31,072,469 		JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 decreases expression ISO Isotretinoin results in decreased expression of ELL2 mRNA CTD PMID:20436886 NCBI chr 2:2,456,189...2,525,590
Ensembl chr 2:2,456,735...2,524,237 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 decreases expression ISO Isotretinoin results in decreased expression of ELOVL1 mRNA CTD PMID:20436886 NCBI chr 5:137,255,868...137,260,486
Ensembl chr 5:137,255,908...137,260,483 		JBrowse link
G Elovl4 ELOVL fatty acid elongase 4 decreases expression ISO Isotretinoin results in decreased expression of ELOVL4 mRNA CTD PMID:20436886 NCBI chr 8:91,310,690...91,338,625
Ensembl chr 8:91,310,630...91,338,843 		JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 decreases expression ISO Isotretinoin results in decreased expression of ELOVL5 mRNA CTD PMID:20436886 NCBI chr 8:85,220,941...85,287,449
Ensembl chr 8:85,259,982...85,285,983 		JBrowse link
G Emp1 epithelial membrane protein 1 increases expression ISO Isotretinoin results in increased expression of EMP1 mRNA CTD PMID:15982314 NCBI chr 4:169,161,076...169,181,967
Ensembl chr 4:169,147,243...169,181,966 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit decreases expression ISO Isotretinoin results in decreased expression of ERCC1 mRNA CTD PMID:20436886 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198 		JBrowse link
G Erg28 ergosterol biosynthesis 28 homolog decreases expression ISO Isotretinoin results in decreased expression of ERG28 mRNA CTD PMID:20436886 NCBI chr 6:109,683,252...109,692,218
Ensembl chr 6:109,683,253...109,692,218 		JBrowse link
G Esr2 estrogen receptor 2 decreases expression EXP Isotretinoin results in decreased expression of ESR2 mRNA CTD PMID:19041696 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251 		JBrowse link
G Etfdh electron transfer flavoprotein dehydrogenase decreases expression ISO Isotretinoin results in decreased expression of ETFDH mRNA CTD PMID:20436886 NCBI chr 2:178,367,547...178,389,641
Ensembl chr 2:178,367,549...178,389,608 		JBrowse link
G Etnk1 ethanolamine kinase 1 decreases expression ISO Isotretinoin results in decreased expression of ETNK1 mRNA CTD PMID:20436886 NCBI chr 4:177,402,904...177,447,047
Ensembl chr 4:177,402,904...177,447,028 		JBrowse link
G Exoc7 exocyst complex component 7 decreases expression ISO Isotretinoin results in decreased expression of EXO70 mRNA CTD PMID:20436886 NCBI chr10:105,242,152...105,259,795
Ensembl chr10:105,242,152...105,259,795 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 decreases expression ISO Isotretinoin results in decreased expression of EYA1 mRNA CTD PMID:31711903 NCBI chr 5:4,275,728...4,495,525
Ensembl chr 5:4,373,626...4,513,142 		JBrowse link
G Fa2h fatty acid 2-hydroxylase decreases expression ISO Isotretinoin results in decreased expression of FA2H mRNA CTD PMID:20436886 NCBI chr19:43,545,380...43,596,788
Ensembl chr19:43,545,378...43,596,801 		JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression EXP Isotretinoin results in increased expression of FABP4 mRNA CTD PMID:19212007 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305 		JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression ISO Isotretinoin results in decreased expression of FABP5 mRNA CTD PMID:15982314 NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378 		JBrowse link
G Fabp6 fatty acid binding protein 6 decreases expression ISO Isotretinoin results in decreased expression of FABP6 mRNA CTD PMID:20436886 NCBI chr10:29,191,621...29,196,593
Ensembl chr10:29,191,623...29,196,563 		JBrowse link
G Fabp7 fatty acid binding protein 7 decreases expression ISO Isotretinoin results in decreased expression of FABP7 mRNA CTD PMID:20436886 NCBI chr20:40,769,624...40,773,156
Ensembl chr20:40,769,586...40,773,349 		JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression ISO Isotretinoin results in decreased expression of FADS1 mRNA CTD PMID:20436886 NCBI chr 1:226,234,034...226,249,118
Ensembl chr 1:226,234,074...226,249,138 		JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression ISO Isotretinoin results in decreased expression of FADS2 mRNA CTD PMID:20436886 NCBI chr 1:225,906,582...226,152,568
Ensembl chr 1:226,114,413...226,152,524 		JBrowse link
G Fam149a family with sequence similarity 149, member A increases expression ISO Isotretinoin results in increased expression of FAM149A mRNA CTD PMID:20436886 NCBI chr16:50,049,816...50,105,962
Ensembl chr16:50,049,828...50,107,856 		JBrowse link
G Fam3c FAM3 metabolism regulating signaling molecule C increases expression
decreases expression		 ISO Isotretinoin results in increased expression of FAM3C mRNA
Isotretinoin results in decreased expression of FAM3C mRNA		 CTD PMID:15982314 PMID:20436886 NCBI chr 4:49,388,962...49,439,892
Ensembl chr 4:49,387,989...49,439,867 		JBrowse link
G Far2 fatty acyl CoA reductase 2 decreases expression ISO Isotretinoin results in decreased expression of FAR2 mRNA CTD PMID:20436886 NCBI chr 4:182,446,400...182,563,485
Ensembl chr 4:182,483,194...182,565,436 		JBrowse link
G Fasn fatty acid synthase decreases expression ISO Isotretinoin results in decreased expression of FASN mRNA CTD PMID:15982314 PMID:20436886 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901 		JBrowse link
G Fastk Fas-activated serine/threonine kinase decreases expression ISO Isotretinoin results in decreased expression of FASTK mRNA CTD PMID:15982314 NCBI chr 4:7,260,521...7,264,590
Ensembl chr 4:7,260,575...7,264,589 		JBrowse link
G Fbln1 fibulin 1 increases expression ISO Isotretinoin results in increased expression of FBLN1 mRNA CTD PMID:20436886 NCBI chr 7:126,096,793...126,176,468
Ensembl chr 7:126,096,793...126,176,468 		JBrowse link
G Fbp1 fructose-bisphosphatase 1 decreases expression ISO Isotretinoin results in decreased expression of FBP1 mRNA CTD PMID:20436886 NCBI chr17:396,175...417,480
Ensembl chr17:396,180...417,480 		JBrowse link
G Fbp2 fructose-bisphosphatase 2 decreases expression ISO Isotretinoin results in decreased expression of FBP2 mRNA CTD PMID:20436886 NCBI chr17:372,554...389,918
Ensembl chr17:372,551...389,967 		JBrowse link
G Fbxl7 F-box and leucine-rich repeat protein 7 increases expression ISO Isotretinoin results in increased expression of FBXL7 mRNA CTD PMID:20436886 NCBI chr 2:79,067,907...79,439,987
Ensembl chr 2:79,067,915...79,078,258 		JBrowse link
G Fbxo9 f-box protein 9 decreases expression ISO Isotretinoin results in decreased expression of FBXO9 mRNA CTD PMID:20436886 NCBI chr 8:85,388,331...85,413,896
Ensembl chr 8:85,388,333...85,413,484 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression ISO Isotretinoin results in decreased expression of FDFT1 mRNA CTD PMID:20436886 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302 		JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression ISO Isotretinoin results in decreased expression of FDPS mRNA CTD PMID:20436886 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219 		JBrowse link
G Fez2 fasciculation and elongation protein zeta 2 increases expression ISO Isotretinoin results in increased expression of FEZ2 mRNA CTD PMID:20436886 NCBI chr 6:963,903...1,003,955
Ensembl chr 6:963,907...1,004,001 		JBrowse link
G Fgf1 fibroblast growth factor 1 decreases expression ISO Isotretinoin results in decreased expression of FGF1 mRNA CTD PMID:15982314 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 increases expression ISO Isotretinoin results in increased expression of FGFR1 mRNA CTD PMID:20436886 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 increases expression ISO Isotretinoin results in increased expression of FGFR3 mRNA CTD PMID:20436886 NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706 		JBrowse link
G Fh fumarate hydratase decreases expression ISO Isotretinoin results in decreased expression of FH mRNA CTD PMID:20436886 NCBI chr13:93,651,486...93,677,371
Ensembl chr13:93,651,484...93,677,377 		JBrowse link
G Fkbp10 FKBP prolyl isomerase 10 increases expression ISO Isotretinoin results in increased expression of FKBP10 mRNA CTD PMID:20436886 NCBI chr10:88,326,337...88,338,199
Ensembl chr10:88,326,080...88,338,207 		JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 decreases expression ISO Isotretinoin results in decreased expression of FKBP8 mRNA CTD PMID:15982314 NCBI chr16:20,645,956...20,652,890
Ensembl chr16:20,645,957...20,652,889 		JBrowse link
G Flg filaggrin decreases expression ISO Isotretinoin results in decreased expression of FLG mRNA CTD PMID:15982314 NCBI chr 2:193,565,401...193,574,297 JBrowse link
G Flna filamin A increases expression ISO Isotretinoin results in increased expression of FLNA mRNA CTD PMID:20436886 NCBI chr  X:156,460,785...156,487,245
Ensembl chr  X:156,463,953...156,487,245 		JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand increases expression ISO Isotretinoin results in increased expression of FLT3LG mRNA CTD PMID:20436886 NCBI chr 1:101,126,006...101,131,413
Ensembl chr 1:101,124,479...101,131,413 		JBrowse link
G Fn1 fibronectin 1 increases expression ISO Isotretinoin results in increased expression of FN1 mRNA CTD PMID:20436886 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Isotretinoin affects the localization of and results in decreased activity of FOS protein CTD PMID:18652567 PMID:19066126 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Isotretinoin results in decreased expression of FOSB mRNA CTD PMID:20436886 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710 		JBrowse link
G Foxc2 forkhead box C2 decreases expression ISO Isotretinoin results in decreased expression of FOXC2 mRNA CTD PMID:31711903 NCBI chr19:53,044,379...53,047,081
Ensembl chr19:53,044,379...53,047,081 		JBrowse link
G Foxd1 forkhead box D1 increases expression ISO Isotretinoin results in increased expression of FOXD1 mRNA CTD PMID:20436886 NCBI chr 2:28,460,068...28,462,488
Ensembl chr 2:28,460,068...28,462,488 		JBrowse link
G Fut8 fucosyltransferase 8 increases expression ISO Isotretinoin results in increased expression of FUT8 mRNA CTD PMID:20436886 NCBI chr 6:100,305,957...100,537,208
Ensembl chr 6:100,337,226...100,537,224 		JBrowse link
G Fyb1 FYN binding protein 1 increases expression ISO Isotretinoin results in increased expression of FYB1 mRNA CTD PMID:18769122 NCBI chr 2:55,834,904...55,983,805
Ensembl chr 2:55,835,151...55,983,804 		JBrowse link
G Fzd5 frizzled class receptor 5 decreases expression ISO Isotretinoin results in decreased expression of FZD5 mRNA CTD PMID:20436886 NCBI chr 9:71,443,784...71,445,541
Ensembl chr 9:71,443,588...71,445,739 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases expression
multiple interactions
increases expression		 ISO Isotretinoin results in decreased expression of G6PD mRNA
Isotretinoin inhibits the reaction [Benzoyl Peroxide results in decreased activity of G6PD protein]
Isotretinoin results in increased expression of G6PD mRNA		 CTD PMID:15225900 PMID:15982314 PMID:20436886 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 decreases expression ISO Isotretinoin results in decreased expression of GABRA4 mRNA CTD PMID:20436886 NCBI chr14:39,154,072...39,230,994
Ensembl chr14:39,154,529...39,231,695 		JBrowse link
G Gal galanin and GMAP prepropeptide decreases expression ISO Isotretinoin results in decreased expression of GAL mRNA CTD PMID:20436886 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925 		JBrowse link
G Gata3 GATA binding protein 3 multiple interactions ISO [vorinostat co-treated with Isotretinoin] results in increased expression of GATA3 mRNA CTD PMID:18769122 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681 		JBrowse link
G Gatd3a glutamine amidotransferase like class 1 domain containing 3A decreases expression ISO Isotretinoin results in decreased expression of GATD3A mRNA CTD PMID:20436886 NCBI chr20:11,244,353...11,252,450
Ensembl chr20:11,244,353...11,252,449 		JBrowse link
G Gba glucosylceramidase beta decreases expression ISO Isotretinoin results in decreased expression of GBA mRNA CTD PMID:15982314 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601 		JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 decreases expression ISO Isotretinoin results in decreased expression of GBE1 mRNA CTD PMID:20436886 NCBI chr11:7,210,169...7,485,895
Ensembl chr11:7,210,209...7,485,890 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit decreases expression ISO Isotretinoin results in decreased expression of GCLM mRNA CTD PMID:20436886 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874 		JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO Isotretinoin results in increased expression of GCNT3 mRNA CTD PMID:18769122 NCBI chr 8:76,449,078...76,459,431
Ensembl chr 8:76,449,081...76,452,554 		JBrowse link
G Gcsh glycine cleavage system protein H decreases expression ISO Isotretinoin results in decreased expression of GCSH mRNA CTD PMID:20436886 NCBI chr19:49,522,054...49,532,811
Ensembl chr19:49,522,054...49,532,811 		JBrowse link
G Gdap1l1 ganglioside-induced differentiation-associated protein 1-like 1 decreases expression ISO Isotretinoin results in decreased expression of GDAP1L1 mRNA CTD PMID:20436886 NCBI chr 3:159,823,791...159,843,260
Ensembl chr 3:159,823,878...159,842,278 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Isotretinoin results in increased expression of GDF15 mRNA CTD PMID:15982314 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978 		JBrowse link
G Gdf2 growth differentiation factor 2 increases expression ISO Isotretinoin results in increased expression of GDF2 mRNA CTD PMID:15982314 NCBI chr16:10,267,510...10,293,545
Ensembl chr16:10,267,482...10,273,239 		JBrowse link
G Ggcx gamma-glutamyl carboxylase decreases expression ISO Isotretinoin results in decreased expression of GGCX mRNA CTD PMID:20436886 NCBI chr 4:100,277,345...100,293,097
Ensembl chr 4:100,277,391...100,293,250 		JBrowse link
G Ggps1 geranylgeranyl diphosphate synthase 1 decreases expression ISO Isotretinoin results in decreased expression of GGPS1 mRNA CTD PMID:20436886 NCBI chr17:53,956,185...53,971,039
Ensembl chr17:53,956,203...53,971,443 		JBrowse link
G Ghitm growth hormone inducible transmembrane protein decreases expression ISO Isotretinoin results in decreased expression of GHITM mRNA CTD PMID:20436886 NCBI chr16:14,370,269...14,382,647
Ensembl chr16:14,371,531...14,382,641 		JBrowse link
G Gins1 GINS complex subunit 1 decreases expression ISO Isotretinoin results in decreased expression of GINS1 mRNA CTD PMID:20436886 NCBI chr 3:146,695,366...146,716,787
Ensembl chr 3:146,695,344...146,716,816 		JBrowse link
G Gk glycerol kinase decreases expression ISO Isotretinoin results in decreased expression of GK mRNA CTD PMID:20436886 NCBI chr  X:54,227,291...54,303,897
Ensembl chr  X:54,227,397...54,303,864 		JBrowse link
G Gldc glycine decarboxylase decreases expression ISO Isotretinoin results in decreased expression of GLDC mRNA CTD PMID:20436886 NCBI chr 1:248,295,140...248,377,122
Ensembl chr 1:248,297,331...248,377,093 		JBrowse link
G Glrx2 glutaredoxin 2 decreases expression ISO Isotretinoin results in decreased expression of GLRX2 mRNA CTD PMID:20436886 NCBI chr13:60,529,057...60,552,115
Ensembl chr13:60,529,932...60,537,916 		JBrowse link
G Glrx5 glutaredoxin 5 decreases expression ISO Isotretinoin results in decreased expression of GLRX5 mRNA CTD PMID:20436886 NCBI chr 6:128,750,503...128,760,880
Ensembl chr 6:128,750,795...128,760,880 		JBrowse link
G Glul glutamate-ammonia ligase increases expression ISO Isotretinoin results in increased expression of GLUL mRNA CTD PMID:15982314 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229 		JBrowse link
G Gng4 G protein subunit gamma 4 decreases expression ISO Isotretinoin results in decreased expression of GNG4 mRNA CTD PMID:20436886 NCBI chr17:90,266,571...90,316,278
Ensembl chr17:90,266,794...90,315,492 		JBrowse link
G Gnpat glyceronephosphate O-acyltransferase decreases expression ISO Isotretinoin results in decreased expression of GNPAT mRNA CTD PMID:20436886 NCBI chr19:57,614,813...57,640,524
Ensembl chr19:57,614,628...57,640,726 		JBrowse link
G Gpr143 G protein-coupled receptor 143 decreases expression ISO Isotretinoin results in decreased expression of GPR143 mRNA CTD PMID:20436886 NCBI chr  X:23,668,363...23,693,162
Ensembl chr  X:23,668,363...23,693,162 		JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO Isotretinoin results in increased expression of GPX2 mRNA CTD PMID:15623509 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245 		JBrowse link
G Gpx3 glutathione peroxidase 3 decreases expression ISO Isotretinoin results in decreased expression of GPX3 mRNA CTD PMID:20436886 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422 		JBrowse link
G Grb7 growth factor receptor bound protein 7 decreases expression ISO Isotretinoin results in decreased expression of GRB7 mRNA CTD PMID:15982314 NCBI chr10:86,393,186...86,408,893
Ensembl chr10:86,399,827...86,409,348 		JBrowse link
G Grpel1 GrpE-like 1, mitochondrial decreases expression ISO Isotretinoin results in decreased expression of GRPEL1 mRNA CTD PMID:20436886 NCBI chr14:79,458,951...79,464,782
Ensembl chr14:79,458,963...79,464,770 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO Isotretinoin inhibits the reaction [Benzoyl Peroxide results in decreased activity of GSR protein] CTD PMID:15225900 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases expression ISO Isotretinoin results in decreased expression of GSTM1 mRNA CTD PMID:15982314 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
affects metabolic processing		 ISO Ethacrynic Acid inhibits the reaction [GSTP1 protein affects the metabolism of Isotretinoin]; S-decylglutathione inhibits the reaction [GSTP1 protein affects the metabolism of Isotretinoin] CTD PMID:9806904 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147 		JBrowse link
G Gstz1 glutathione S-transferase zeta 1 decreases expression ISO Isotretinoin results in decreased expression of GSTZ1 mRNA CTD PMID:20436886 NCBI chr 6:111,176,798...111,187,246
Ensembl chr 6:111,176,798...111,187,244 		JBrowse link
G H1f2 H1.2 linker histone, cluster member decreases expression ISO Isotretinoin results in decreased expression of H1-2 mRNA CTD PMID:20436886 NCBI chr17:43,638,938...43,640,445
Ensembl chr17:43,639,749...43,640,387 		JBrowse link
G H2ax H2A.X variant histone decreases expression ISO Isotretinoin results in decreased expression of H2AX mRNA CTD PMID:20436886 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981 		JBrowse link
G H2bc12 H2B clustered histone 12 decreases expression ISO Isotretinoin results in decreased expression of H2BC12 mRNA CTD PMID:20436886 NCBI chr17:44,527,421...44,527,801
Ensembl chr17:44,527,421...44,527,801 		JBrowse link
G H2bc9 H2B clustered histone 9 decreases expression ISO Isotretinoin results in decreased expression of H2BC9 mRNA CTD PMID:20436886 NCBI chr17:44,519,815...44,520,269
Ensembl chr17:44,519,860...44,520,240 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase decreases expression ISO Isotretinoin results in decreased expression of HADH mRNA CTD PMID:20436886 NCBI chr 2:236,353,445...236,395,067
Ensembl chr 2:236,353,445...236,395,067 		JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression ISO Isotretinoin results in decreased expression of HAO2 mRNA CTD PMID:20436886 NCBI chr 2:200,785,492...200,808,868
Ensembl chr 2:200,778,122...200,808,857 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Isotretinoin results in increased expression of HBEGF mRNA CTD PMID:15982314 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403 		JBrowse link
G Hcls1 hematopoietic cell specific Lyn substrate 1 increases expression ISO Isotretinoin results in increased expression of HCLS1 mRNA CTD PMID:20436886 NCBI chr11:66,736,966...66,759,402
Ensembl chr11:66,736,966...66,759,402 		JBrowse link
G Hcn3 hyperpolarization-activated cyclic nucleotide-gated potassium channel 3 decreases expression ISO Isotretinoin results in decreased expression of HCN3 mRNA CTD PMID:20436886 NCBI chr 2:188,458,851...188,471,916
Ensembl chr 2:188,454,853...188,471,988 		JBrowse link
G Hgd homogentisate 1, 2-dioxygenase decreases expression ISO Isotretinoin results in decreased expression of HGD mRNA CTD PMID:20436886 NCBI chr11:65,983,221...66,034,555
Ensembl chr11:65,983,221...66,034,573 		JBrowse link
G Hgf hepatocyte growth factor decreases expression
decreases secretion		 ISO Isotretinoin results in decreased expression of HGF mRNA
Isotretinoin results in decreased secretion of HGF protein		 CTD PMID:11223164 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362 		JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase decreases expression ISO Isotretinoin results in decreased expression of HIBCH mRNA CTD PMID:20436886 NCBI chr 9:53,446,185...53,526,727
Ensembl chr 9:53,446,194...53,526,728 		JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated decreases expression ISO Isotretinoin results in decreased expression of HILPDA mRNA CTD PMID:20436886 NCBI chr 4:56,547,600...56,550,584
Ensembl chr 4:56,549,739...56,549,993 		JBrowse link
G Hip1 huntingtin interacting protein 1 increases expression ISO Isotretinoin results in increased expression of HIP1 mRNA CTD PMID:20436886 NCBI chr12:24,180,795...24,315,373
Ensembl chr12:24,180,937...24,315,373 		JBrowse link
G Hist1h2af histone cluster 1 H2A family member F decreases expression ISO Isotretinoin results in decreased expression of H2AC8 mRNA CTD PMID:20436886 NCBI chr17:43,627,237...43,627,629
Ensembl chr17:43,627,237...43,627,629 		JBrowse link
G Hist1h2ah histone cluster 1 H2A family member H decreases expression ISO Isotretinoin results in decreased expression of H2AC11 mRNA CTD PMID:20436886 NCBI chr17:43,632,354...43,632,851
Ensembl chr17:44,747,796...44,748,188
Ensembl chr17:44,747,796...44,748,188 		JBrowse link
G Hist1h2bd histone cluster 1 H2B family member D decreases expression ISO Isotretinoin results in decreased expression of H2BC5 mRNA CTD PMID:20436886 NCBI chr17:44,833,924...44,834,305
Ensembl chr17:44,833,924...44,834,305 		JBrowse link
G Hlcs holocarboxylase synthetase decreases expression ISO Isotretinoin results in decreased expression of HLCS mRNA CTD PMID:20436886 NCBI chr11:34,357,372...34,537,798
Ensembl chr11:34,352,287...34,526,931 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO Isotretinoin results in decreased expression of HMGCR mRNA CTD PMID:20436886 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO Isotretinoin results in decreased expression of HMGCS1 mRNA CTD PMID:20436886 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression ISO Isotretinoin results in decreased expression of HSD11B1 mRNA CTD PMID:15982314 PMID:20436886 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603 		JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 decreases expression ISO Isotretinoin results in decreased expression of HSD17B12 mRNA CTD PMID:20436886 NCBI chr 3:82,924,699...83,048,465
Ensembl chr 3:82,924,687...83,048,435 		JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 decreases expression ISO Isotretinoin results in decreased expression of HSD17B7 mRNA CTD PMID:20436886 NCBI chr13:88,288,116...88,308,019
Ensembl chr13:88,288,046...88,307,988 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO Isotretinoin results in decreased expression of HSD3B1 mRNA CTD PMID:20436886
G Hsp90b1 heat shock protein 90 beta family member 1 decreases expression ISO Isotretinoin results in decreased expression of HSP90B1 mRNA CTD PMID:20436886 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533 		JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 decreases expression ISO Isotretinoin results in decreased expression of HSPA9 mRNA CTD PMID:20436886 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression ISO Isotretinoin results in decreased expression of HSPD1 mRNA CTD PMID:20436886 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956 		JBrowse link
G Htra1 HtrA serine peptidase 1 increases expression ISO Isotretinoin results in increased expression of HTRA1 mRNA CTD PMID:20436886 NCBI chr 1:201,499,067...201,548,508
Ensembl chr 1:201,499,028...201,548,513 		JBrowse link
G Hus1 HUS1 checkpoint clamp component decreases expression ISO Isotretinoin results in decreased expression of HUS1 mRNA CTD PMID:20436886 NCBI chr14:89,194,086...89,208,825
Ensembl chr14:89,194,092...89,208,825 		JBrowse link
G Icam2 intercellular adhesion molecule 2 increases expression ISO Isotretinoin results in increased expression of ICAM2 mRNA CTD PMID:20436886 NCBI chr10:94,569,889...94,581,218
Ensembl chr10:94,569,890...94,576,512 		JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 decreases expression ISO Isotretinoin results in decreased expression of IDH1 mRNA CTD PMID:20436886 NCBI chr 9:71,882,108...71,911,645
Ensembl chr 9:71,882,105...71,900,044 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO Isotretinoin results in decreased expression of IDI1 mRNA CTD PMID:20436886 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036 		JBrowse link
G Ier3 immediate early response 3 decreases expression ISO Isotretinoin results in decreased expression of IER3 mRNA CTD PMID:20436886 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769 		JBrowse link
G Ifi35 interferon-induced protein 35 increases expression ISO Isotretinoin results in increased expression of IFI35 mRNA CTD PMID:20436886 NCBI chr10:89,358,376...89,366,628
Ensembl chr10:89,358,376...89,366,626 		JBrowse link
G Ifrd1 interferon-related developmental regulator 1 decreases expression ISO Isotretinoin results in decreased expression of IFRD1 mRNA CTD PMID:20436886 NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420 		JBrowse link
G Ift20 intraflagellar transport 20 decreases expression ISO Isotretinoin results in decreased expression of IFT20 mRNA CTD PMID:20436886 NCBI chr10:65,805,808...65,811,353
Ensembl chr10:65,805,860...65,811,351 		JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO Isotretinoin results in increased expression of IGF1 mRNA CTD PMID:15982314 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression ISO Isotretinoin results in increased expression of IGFBP3 mRNA CTD PMID:18769122 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 increases expression ISO Isotretinoin results in increased expression of IGFBP4 mRNA CTD PMID:20436886 NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 increases expression ISO Isotretinoin results in increased expression of IGFBP5 mRNA CTD PMID:20436886 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033 		JBrowse link
G Il10 interleukin 10 decreases expression
decreases secretion		 EXP Isotretinoin results in decreased expression of IL10 mRNA
Isotretinoin results in decreased secretion of IL10 protein		 CTD PMID:15972972 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Il10ra interleukin 10 receptor subunit alpha decreases expression ISO Isotretinoin results in decreased expression of IL10RA mRNA CTD PMID:15982314 NCBI chr 8:49,558,062...49,573,891
Ensembl chr 8:49,560,035...49,573,742 		JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 decreases expression ISO Isotretinoin results in decreased expression of IL13RA1 mRNA CTD PMID:20436886 NCBI chr  X:122,724,081...122,783,801
Ensembl chr  X:122,724,129...122,781,479 		JBrowse link
G Il1a interleukin 1 alpha decreases secretion EXP Isotretinoin results in decreased secretion of IL1A protein CTD PMID:15972972 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086 		JBrowse link
G Il1b interleukin 1 beta decreases expression
decreases secretion
multiple interactions
increases expression		 ISO
EXP		 Isotretinoin results in decreased expression of IL1B mRNA
Isotretinoin results in decreased secretion of IL1B protein
[vorinostat co-treated with Isotretinoin] results in increased expression of IL1B mRNA
Isotretinoin results in increased expression of IL1B mRNA		 CTD PMID:15972972 PMID:15982314 PMID:18769122 PMID:20436886 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 decreases expression ISO Isotretinoin results in decreased expression of IL1R2 mRNA CTD PMID:20436886 NCBI chr 9:46,840,646...46,881,241
Ensembl chr 9:46,840,992...46,881,264 		JBrowse link
G Il2 interleukin 2 decreases secretion EXP Isotretinoin results in decreased secretion of IL2 protein CTD PMID:15972972 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854 		JBrowse link
G Il24 interleukin 24 decreases expression ISO Isotretinoin results in decreased expression of IL24 mRNA CTD PMID:15982314 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849 		JBrowse link
G Il4 interleukin 4 decreases secretion EXP Isotretinoin results in decreased secretion of IL4 protein CTD PMID:15972972 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531 		JBrowse link
G Il6 interleukin 6 decreases expression
decreases secretion		 ISO
EXP		 Isotretinoin results in decreased expression of IL6 mRNA
Isotretinoin results in decreased secretion of IL6 protein		 CTD PMID:15972972 PMID:17033190 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B decreases expression ISO Isotretinoin results in decreased expression of INPP4B mRNA CTD PMID:20436886 NCBI chr19:29,592,889...30,341,528
Ensembl chr19:29,597,905...29,968,424 		JBrowse link
G Insig1 insulin induced gene 1 decreases expression ISO Isotretinoin results in decreased expression of INSIG1 mRNA CTD PMID:20436886 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515 		JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO Isotretinoin promotes the reaction [Dacarbazine results in increased expression of IRF1 mRNA] CTD PMID:17973783 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531 		JBrowse link
G Isca1 iron-sulfur cluster assembly 1 decreases expression ISO Isotretinoin results in decreased expression of ISCA1 mRNA CTD PMID:20436886 NCBI chr17:5,281,727...5,294,386
Ensembl chr17:5,281,727...5,294,384 		JBrowse link
G Islr immunoglobulin superfamily containing leucine-rich repeat increases expression ISO Isotretinoin results in increased expression of ISLR mRNA CTD PMID:20436886 NCBI chr 8:62,946,732...62,949,675
Ensembl chr 8:62,946,732...62,948,720 		JBrowse link
G Isoc1 isochorismatase domain containing 1 decreases expression ISO Isotretinoin results in decreased expression of ISOC1 mRNA CTD PMID:20436886 NCBI chr18:53,727,203...53,747,612
Ensembl chr18:53,727,209...53,745,200 		JBrowse link
G Itga4 integrin subunit alpha 4 increases expression ISO Isotretinoin results in increased expression of ITGA4 mRNA CTD PMID:15982314 NCBI chr 3:66,178,745...66,265,547
Ensembl chr 3:66,193,059...66,263,960 		JBrowse link
G Itgav integrin subunit alpha V increases expression ISO Isotretinoin results in increased expression of ITGAV mRNA CTD PMID:20436886 NCBI chr 3:71,113,269...71,205,958
Ensembl chr 3:71,114,100...71,202,411 		JBrowse link
G Itgb2 integrin subunit beta 2 increases expression ISO Isotretinoin results in increased expression of ITGB2 mRNA CTD PMID:20436886 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647 		JBrowse link
G Jak1 Janus kinase 1 increases expression ISO Isotretinoin results in increased expression of JAK1 mRNA CTD PMID:20436886 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904 		JBrowse link
G Kank2 KN motif and ankyrin repeat domains 2 increases expression ISO Isotretinoin results in increased expression of KANK2 mRNA CTD PMID:20436886 NCBI chr 8:22,792,000...22,821,459
Ensembl chr 8:22,791,995...22,821,397 		JBrowse link
G Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 decreases expression ISO Isotretinoin results in decreased expression of KCNJ15 mRNA CTD PMID:20436886 NCBI chr11:35,545,185...35,588,517
Ensembl chr11:35,568,182...35,585,390 		JBrowse link
G Kcnk1 potassium two pore domain channel subfamily K member 1 decreases expression ISO Isotretinoin results in decreased expression of KCNK1 mRNA CTD PMID:20436886 NCBI chr19:58,823,836...58,862,926
Ensembl chr19:58,823,814...58,862,926 		JBrowse link
G Kctd12 potassium channel tetramerization domain containing 12 increases expression ISO Isotretinoin results in increased expression of KCTD12 mRNA CTD PMID:20436886 NCBI chr15:87,384,632...87,390,627 JBrowse link
G Klhdc4 kelch domain containing 4 decreases expression ISO Isotretinoin results in decreased expression of KLHDC4 mRNA CTD PMID:20436886 NCBI chr19:54,651,911...54,652,381
Ensembl chr19:54,651,911...54,652,381 		JBrowse link
G Kras KRAS proto-oncogene, GTPase decreases expression ISO Isotretinoin results in decreased expression of KRAS mRNA CTD PMID:20436886 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558 		JBrowse link
G Krt1 keratin 1 decreases expression ISO Isotretinoin results in decreased expression of KRT1 mRNA CTD PMID:15982314 NCBI chr 7:143,448,318...143,453,544
Ensembl chr 7:143,448,318...143,453,544 		JBrowse link
G Krt10 keratin 10 decreases expression ISO Isotretinoin results in decreased expression of KRT10 mRNA CTD PMID:15982314 NCBI chr10:87,296,445...87,301,307
Ensembl chr10:87,296,451...87,300,736 		JBrowse link
G Krt14 keratin 14 decreases expression ISO Isotretinoin results in decreased expression of KRT14 mRNA; Isotretinoin results in decreased expression of KRT14 protein CTD PMID:15982314 NCBI chr10:88,118,029...88,122,233
Ensembl chr10:88,055,823...88,122,233 		JBrowse link
G Krt15 keratin 15 increases expression ISO Isotretinoin results in increased expression of KRT15 mRNA CTD PMID:15982314 NCBI chr10:88,046,803...88,050,622
Ensembl chr10:88,046,803...88,050,622 		JBrowse link
G Krt16 keratin 16 decreases expression ISO Isotretinoin results in decreased expression of KRT16 mRNA CTD PMID:20436886 NCBI chr10:88,149,210...88,152,167
Ensembl chr10:88,149,345...88,152,064 		JBrowse link
G Krt17 keratin 17 decreases expression ISO Isotretinoin results in decreased expression of KRT17 mRNA; Isotretinoin results in decreased expression of KRT17 protein CTD PMID:15982314 PMID:18769122 NCBI chr10:88,158,993...88,163,712
Ensembl chr10:88,118,001...88,163,723 		JBrowse link
G Krt19 keratin 19 increases expression ISO Isotretinoin results in increased expression of KRT19 mRNA; Isotretinoin results in increased expression of KRT19 protein CTD PMID:15982314 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561 		JBrowse link
G Krt5 keratin 5 decreases expression ISO Isotretinoin results in decreased expression of KRT5 mRNA CTD PMID:15982314 NCBI chr 7:143,320,142...143,324,536
Ensembl chr 7:143,316,920...143,453,546 		JBrowse link
G Krt7 keratin 7 increases expression ISO Isotretinoin results in increased expression of KRT7 mRNA; Isotretinoin results in increased expression of KRT7 protein CTD PMID:15982314 NCBI chr 7:143,059,731...143,075,907
Ensembl chr 7:143,059,764...143,075,907 		JBrowse link
G Krt75 keratin 75 decreases expression ISO Isotretinoin results in decreased expression of KRT75 mRNA CTD PMID:15982314 NCBI chr 7:143,219,012...143,228,237
Ensembl chr 7:143,219,012...143,228,060 		JBrowse link
G Lactb2 lactamase, beta 2 decreases expression ISO Isotretinoin results in decreased expression of LACTB2 mRNA CTD PMID:20436886 NCBI chr 5:4,982,348...5,005,111
Ensembl chr 5:4,982,348...5,005,109 		JBrowse link
G Lage3 L antigen family, member 3 decreases expression ISO Isotretinoin results in decreased expression of LAGE3 mRNA CTD PMID:20436886 NCBI chr  X:156,355,376...156,356,799
Ensembl chr  X:156,355,376...156,356,799 		JBrowse link
G Lama2 laminin subunit alpha 2 decreases expression
increases expression		 ISO Isotretinoin results in decreased expression of LAMA2 mRNA
Isotretinoin results in increased expression of LAMA2 mRNA		 CTD PMID:15982314 PMID:20436886 NCBI chr 1:18,491,264...19,143,486
Ensembl chr 1:18,491,384...19,143,269 		JBrowse link
G Lama3 laminin subunit alpha 3 decreases expression ISO Isotretinoin results in decreased expression of LAMA3 mRNA CTD PMID:15982314 NCBI chr18:3,704,866...3,941,215
Ensembl chr18:3,705,916...3,940,838 		JBrowse link
G Lamc1 laminin subunit gamma 1 increases expression ISO Isotretinoin results in increased expression of LAMC1 mRNA CTD PMID:20436886 NCBI chr13:70,656,727...70,783,515
Ensembl chr13:70,658,707...70,783,515 		JBrowse link
G Lamc3 laminin subunit gamma 3 increases expression ISO Isotretinoin results in increased expression of LAMC3 mRNA CTD PMID:15982314 NCBI chr 3:9,265,407...9,327,107
Ensembl chr 3:9,267,122...9,326,993 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 increases expression ISO Isotretinoin results in increased expression of LAPTM5 mRNA CTD PMID:20436886 NCBI chr 5:149,015,793...149,069,719
Ensembl chr 5:149,047,681...149,069,719 		JBrowse link
G Larp4 La ribonucleoprotein 4 decreases expression ISO Isotretinoin results in decreased expression of LARP4 mRNA CTD PMID:20436886 NCBI chr 7:141,630,229...141,676,242 JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase increases expression ISO Isotretinoin results in increased expression of LCK mRNA CTD PMID:20436886 NCBI chr 5:147,750,976...147,779,627
Ensembl chr 5:147,750,973...147,761,983 		JBrowse link
G Lcn2 lipocalin 2 increases expression ISO Isotretinoin results in increased expression of LCN2 mRNA CTD PMID:15982314 PMID:18769122 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546 		JBrowse link
G Lcp2 lymphocyte cytosolic protein 2 increases expression ISO Isotretinoin results in increased expression of LCP2 mRNA CTD PMID:20436886 NCBI chr10:18,996,523...19,043,289
Ensembl chr10:18,996,523...19,043,286 		JBrowse link
G Ldlr low density lipoprotein receptor decreases expression ISO Isotretinoin results in decreased expression of LDLR mRNA CTD PMID:20436886 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903 		JBrowse link
G Lep leptin increases expression EXP Isotretinoin results in increased expression of LEP mRNA CTD PMID:19212007 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818 		JBrowse link
G Lhfpl6 LHFPL tetraspan subfamily member 6 increases expression ISO Isotretinoin results in increased expression of LHFPL6 mRNA CTD PMID:20436886 NCBI chr 2:142,262,236...142,461,980
Ensembl chr 2:142,262,236...142,461,980 		JBrowse link
G Limch1 LIM and calponin homology domains 1 increases expression ISO Isotretinoin results in increased expression of LIMCH1 mRNA CTD PMID:20436886 NCBI chr14:42,760,363...43,072,976
Ensembl chr14:42,762,587...43,072,843 		JBrowse link
G Lipc lipase C, hepatic type increases expression ISO Isotretinoin results in increased expression of LIPC mRNA CTD PMID:20436886 NCBI chr 8:77,272,582...77,398,485
Ensembl chr 8:77,272,570...77,398,248 		JBrowse link
G Lmnb1 lamin B1 increases expression ISO Isotretinoin results in increased expression of LMNB1 protein CTD PMID:15982314 NCBI chr18:51,785,111...51,822,264
Ensembl chr18:51,785,111...51,822,264 		JBrowse link
G Lmo2 LIM domain only 2 increases expression ISO Isotretinoin results in increased expression of LMO2 mRNA CTD PMID:20436886 NCBI chr 3:93,909,156...93,931,888
Ensembl chr 3:93,909,156...93,931,871 		JBrowse link
G LOC299277 similar to serine (or cysteine) peptidase inhibitor, clade A, member 3B increases expression ISO Isotretinoin results in increased expression of SERPINA3 mRNA CTD PMID:15982314 NCBI chr 6:127,871,895...127,888,287
Ensembl chr 6:127,872,666...127,886,540 		JBrowse link
G Loxl2 lysyl oxidase-like 2 increases expression ISO Isotretinoin results in increased expression of LOXL2 mRNA CTD PMID:20436886 NCBI chr15:51,276,022...51,365,238
Ensembl chr15:51,303,909...51,365,234 		JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 decreases expression ISO Isotretinoin results in decreased expression of LPCAT3 mRNA CTD PMID:20436886 NCBI chr 4:157,181,722...157,222,997
Ensembl chr 4:157,181,795...157,222,996 		JBrowse link
G Lpin1 lipin 1 decreases expression ISO Isotretinoin results in decreased expression of LPIN1 mRNA CTD PMID:20436886 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046 		JBrowse link
G Lrat lecithin retinol acyltransferase increases expression ISO Isotretinoin results in increased expression of LRAT protein CTD PMID:15982314 NCBI chr 2:181,896,304...181,905,366
Ensembl chr 2:181,896,305...181,905,300 		JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 increases expression ISO Isotretinoin results in increased expression of LTBP1 mRNA CTD PMID:20436886 NCBI chr 6:21,203,502...21,600,441
Ensembl chr 6:21,203,502...21,600,451 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase increases expression ISO Isotretinoin results in increased expression of LYN mRNA CTD PMID:20436886 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648 		JBrowse link
G Maff MAF bZIP transcription factor F decreases expression ISO Isotretinoin results in decreased expression of MAFF mRNA CTD PMID:20436886 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095 		JBrowse link
G Man1a1 mannosidase, alpha, class 1A, member 1 increases expression ISO Isotretinoin results in increased expression of MAN1A1 mRNA CTD PMID:20436886 NCBI chr20:35,257,688...35,450,132
Ensembl chr20:35,257,985...35,450,513 		JBrowse link
G Map4 microtubule-associated protein 4 increases expression ISO Isotretinoin results in increased expression of MAP4 mRNA CTD PMID:20436886 NCBI chr 8:118,013,584...118,159,934
Ensembl chr 8:118,013,612...118,159,933 		JBrowse link
G Mboat2 membrane bound O-acyltransferase domain containing 2 decreases expression ISO Isotretinoin results in decreased expression of MBOAT2 mRNA CTD PMID:20436886 NCBI chr 6:44,009,872...44,135,501
Ensembl chr 6:44,009,872...44,131,387 		JBrowse link
G Mc5r melanocortin 5 receptor decreases expression ISO Isotretinoin results in decreased expression of MC5R mRNA CTD PMID:20436886 NCBI chr18:64,113,659...64,118,700
Ensembl chr18:64,114,933...64,116,524 		JBrowse link
G Mcat malonyl-CoA-acyl carrier protein transacylase decreases expression ISO Isotretinoin results in decreased expression of MCAT mRNA CTD PMID:20436886 NCBI chr 7:124,412,762...124,424,966
Ensembl chr 7:124,412,762...124,423,832 		JBrowse link
G Mccc1 methylcrotonoyl-CoA carboxylase 1 decreases expression ISO Isotretinoin results in decreased expression of MCCC1 mRNA CTD PMID:20436886 NCBI chr 2:122,550,777...122,690,540
Ensembl chr 2:122,550,775...122,690,617 		JBrowse link
G Mccc2 methylcrotonoyl-CoA carboxylase 2 decreases expression ISO Isotretinoin results in decreased expression of MCCC2 mRNA CTD PMID:20436886 NCBI chr 2:30,175,017...30,246,028
Ensembl chr 2:30,175,018...30,246,010 		JBrowse link
G Mcfd2 multiple coagulation factor deficiency 2, ER cargo receptor complex subunit decreases expression ISO Isotretinoin results in decreased expression of MCFD2 mRNA CTD PMID:20436886 NCBI chr 6:10,887,303...10,899,221
Ensembl chr 6:10,887,288...10,899,200 		JBrowse link
G Mcts1 MCTS1, re-initiation and release factor decreases expression ISO Isotretinoin results in decreased expression of MCTS1 mRNA CTD PMID:20436886 NCBI chr  X:124,894,269...124,906,129
Ensembl chr  X:124,894,466...124,906,162 		JBrowse link
G Mcur1 mitochondrial calcium uniporter regulator 1 decreases expression ISO Isotretinoin results in decreased expression of MCUR1 mRNA CTD PMID:20436886 NCBI chr17:24,165,259...24,182,425
Ensembl chr17:24,165,280...24,182,425 		JBrowse link
G Mdh1 malate dehydrogenase 1 decreases expression ISO Isotretinoin results in decreased expression of MDH1 mRNA CTD PMID:20436886 NCBI chr14:106,378,349...106,393,642
Ensembl chr14:106,378,942...106,393,670 		JBrowse link
G Me1 malic enzyme 1 decreases expression ISO Isotretinoin results in decreased expression of ME1 mRNA CTD PMID:20436886 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834 		JBrowse link
G Mecr mitochondrial trans-2-enoyl-CoA reductase decreases expression ISO Isotretinoin results in decreased expression of MECR mRNA CTD PMID:20436886 NCBI chr 5:150,001,281...150,027,407
Ensembl chr 5:150,001,281...150,027,049 		JBrowse link
G Mef2c myocyte enhancer factor 2C increases expression ISO Isotretinoin results in increased expression of MEF2C mRNA CTD PMID:20436886 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787 		JBrowse link
G Meox1 mesenchyme homeobox 1 decreases expression ISO Isotretinoin results in decreased expression of MEOX1 mRNA CTD PMID:31711903 NCBI chr10:89,797,011...89,817,009
Ensembl chr10:89,797,038...89,816,491 		JBrowse link
G Mesp2 mesoderm posterior bHLH transcription factor 2 decreases expression ISO Isotretinoin results in decreased expression of MESP2 mRNA CTD PMID:31711903 NCBI chr 1:141,550,633...141,553,239
Ensembl chr 1:141,550,633...141,553,230 		JBrowse link
G Mfap2 microfibril associated protein 2 decreases expression
increases expression		 ISO Isotretinoin results in decreased expression of MFAP2 mRNA
Isotretinoin results in increased expression of MFAP2 mRNA		 CTD PMID:15982314 PMID:20436886 NCBI chr 5:159,534,202...159,539,750
Ensembl chr 5:159,534,202...159,539,750 		JBrowse link
G Mfap3l microfibril associated protein 3 like decreases expression ISO Isotretinoin results in decreased expression of MFAP3L mRNA CTD PMID:20436886 NCBI chr16:32,734,059...32,777,091
Ensembl chr16:32,738,265...32,753,278 		JBrowse link
G Mfap4 microfibril associated protein 4 increases expression ISO Isotretinoin results in increased expression of MFAP4 mRNA CTD PMID:20436886 NCBI chr10:47,765,463...47,768,484
Ensembl chr10:47,765,432...47,768,483 		JBrowse link
G Mlana melan-A decreases expression ISO Isotretinoin results in decreased expression of MLANA mRNA CTD PMID:20436886 NCBI chr 1:247,869,756...247,883,558
Ensembl chr 1:247,869,756...247,884,442 		JBrowse link
G Mmp10 matrix metallopeptidase 10 decreases expression ISO Isotretinoin results in decreased expression of MMP10 mRNA CTD PMID:15982314 NCBI chr 8:5,734,348...5,742,243
Ensembl chr 8:5,734,348...5,742,243 		JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions
decreases expression		 ISO Isotretinoin inhibits the reaction [Arachidonic Acid results in increased expression of MMP13 mRNA]; Isotretinoin inhibits the reaction [Arachidonic Acid results in increased secretion of MMP13 protein]
Isotretinoin results in decreased expression of MMP13 protein		 CTD PMID:16185265 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression		 ISO Isotretinoin inhibits the reaction [Arachidonic Acid results in increased expression of MMP2 mRNA]; Isotretinoin inhibits the reaction [Arachidonic Acid results in increased secretion of MMP2 protein]
Isotretinoin results in increased expression of MMP2 mRNA		 CTD PMID:16185265 PMID:20436886 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611 		JBrowse link
G Mmp23 matrix metallopeptidase 23 increases expression ISO Isotretinoin results in increased expression of MMP23B mRNA CTD PMID:20436886 NCBI chr 5:173,078,811...173,082,834
Ensembl chr 5:173,078,590...173,081,839 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression		 ISO Isotretinoin inhibits the reaction [Arachidonic Acid results in increased expression of MMP9 mRNA]; Isotretinoin inhibits the reaction [Arachidonic Acid results in increased secretion of MMP9 protein]
Isotretinoin results in decreased expression of MMP9 protein		 CTD PMID:16185265 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520 		JBrowse link
G Mocos molybdenum cofactor sulfurase decreases expression ISO Isotretinoin results in decreased expression of MOCOS mRNA CTD PMID:20436886 NCBI chr18:16,590,086...16,636,312
Ensembl chr18:16,590,197...16,636,084 		JBrowse link
G Mospd1 motile sperm domain containing 1 decreases expression ISO Isotretinoin results in decreased expression of MOSPD1 mRNA CTD PMID:20436886 NCBI chr  X:157,745,939...157,774,505
Ensembl chr  X:157,759,624...157,773,108 		JBrowse link
G Mpc1 mitochondrial pyruvate carrier 1 decreases expression ISO Isotretinoin results in decreased expression of MPC1 mRNA CTD PMID:20436886 NCBI chr 1:53,026,608...53,038,229
Ensembl chr 1:53,026,608...53,038,229 		JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 decreases expression ISO Isotretinoin results in decreased expression of MPC2 mRNA CTD PMID:20436886 NCBI chr13:83,680,527...83,700,491
Ensembl chr13:83,681,322...83,700,213 		JBrowse link
G Mrpl33 mitochondrial ribosomal protein L33 decreases expression ISO Isotretinoin results in decreased expression of MRPL33 mRNA CTD PMID:20436886 NCBI chr 6:26,130,278...26,138,498
Ensembl chr 6:26,130,488...26,138,414 		JBrowse link
G Mrps16 mitochondrial ribosomal protein S16 decreases expression ISO Isotretinoin results in decreased expression of MRPS16 mRNA CTD PMID:20436886 NCBI chr15:4,351,292...4,353,694
Ensembl chr15:4,351,292...4,353,694 		JBrowse link
G Mrps18a mitochondrial ribosomal protein S18A decreases expression ISO Isotretinoin results in decreased expression of MRPS18A mRNA CTD PMID:20436886 NCBI chr 9:17,238,354...17,254,845
Ensembl chr 9:17,238,385...17,254,949 		JBrowse link
G Mrps33 mitochondrial ribosomal protein S33 decreases expression ISO Isotretinoin results in decreased expression of MRPS33 mRNA CTD PMID:20436886 NCBI chr 4:67,606,971...67,616,056
Ensembl chr 4:67,607,273...67,610,710 		JBrowse link
G Mrs2 magnesium transporter MRS2 decreases expression ISO Isotretinoin results in decreased expression of MRS2 mRNA CTD PMID:20436886 NCBI chr17:42,064,271...42,083,602
Ensembl chr17:42,064,376...42,082,300 		JBrowse link
G Mrtfb myocardin related transcription factor B increases expression ISO Isotretinoin results in increased expression of MRTFB mRNA CTD PMID:20436886 NCBI chr10:1,151,163...1,273,269 JBrowse link
G Msmb microseminoprotein, beta increases expression ISO Isotretinoin results in increased expression of MSMB mRNA CTD PMID:20436886 NCBI chr16:8,280,275...8,300,853
Ensembl chr16:8,280,275...8,300,852 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases expression ISO Isotretinoin results in decreased expression of MSMO1 mRNA CTD PMID:20436886 NCBI chr16:26,859,441...26,875,880
Ensembl chr16:26,859,397...26,875,973 		JBrowse link
G Msrb1 methionine sulfoxide reductase B1 decreases expression ISO Isotretinoin results in decreased expression of MSRB1 mRNA CTD PMID:20436886 NCBI chr10:14,105,750...14,111,463
Ensembl chr10:14,105,750...14,111,463 		JBrowse link
G Mtch2 mitochondrial carrier 2 decreases expression ISO Isotretinoin results in decreased expression of MTCH2 mRNA CTD PMID:20436886 NCBI chr 3:79,678,141...79,695,356
Ensembl chr 3:79,678,201...79,694,006 		JBrowse link
G Mto1 mitochondrial tRNA translation optimization 1 decreases expression ISO Isotretinoin results in decreased expression of MTO1 mRNA CTD PMID:20436886 NCBI chr 8:85,807,703...85,832,263
Ensembl chr 8:85,808,125...85,831,937 		JBrowse link
G Mtx1 Metaxin 1 decreases expression ISO Isotretinoin results in decreased expression of MTX1 mRNA CTD PMID:20436886 NCBI chr 2:188,522,605...188,528,747
Ensembl chr 2:188,521,785...188,528,195 		JBrowse link
G Muc1 mucin 1, cell surface associated decreases expression ISO Isotretinoin results in decreased expression of MUC1 mRNA CTD PMID:20436886 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874 		JBrowse link
G Mvd mevalonate diphosphate decarboxylase decreases expression ISO Isotretinoin results in decreased expression of MVD mRNA CTD PMID:20436886 NCBI chr19:55,258,910...55,268,933
Ensembl chr19:55,258,905...55,268,951 		JBrowse link
G Mvk mevalonate kinase decreases expression ISO Isotretinoin results in decreased expression of MVK mRNA CTD PMID:20436886 NCBI chr12:47,904,266...47,920,457
Ensembl chr12:47,904,719...47,919,400 		JBrowse link
G Mycbp Myc binding protein decreases expression ISO Isotretinoin results in decreased expression of MYCBP mRNA CTD PMID:20436886 NCBI chr 5:141,560,192...141,567,399
Ensembl chr 5:141,560,192...141,567,399 		JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor decreases expression
multiple interactions		 ISO Isotretinoin results in decreased expression of MYCN mRNA
R116010 promotes the reaction [Isotretinoin results in decreased expression of MYCN mRNA]		 CTD PMID:17486130 NCBI chr 6:38,222,554...38,228,419
Ensembl chr 6:38,222,555...38,228,379 		JBrowse link
G Myl4 myosin, light chain 4 decreases expression ISO Isotretinoin results in decreased expression of MYL4 mRNA CTD PMID:20436886 NCBI chr10:92,628,356...92,638,100
Ensembl chr10:92,628,356...92,638,100 		JBrowse link
G Myod1 myogenic differentiation 1 decreases expression ISO Isotretinoin results in decreased expression of MYOD1 mRNA CTD PMID:20436886 NCBI chr 1:102,396,538...102,399,248
Ensembl chr 1:102,396,538...102,399,248 		JBrowse link
G Nadk NAD kinase decreases expression ISO Isotretinoin results in decreased expression of NADK mRNA CTD PMID:20436886 NCBI chr 5:172,984,930...173,015,505
Ensembl chr 5:172,986,291...173,015,494 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase decreases expression ISO Isotretinoin results in decreased expression of NAMPT mRNA CTD PMID:20436886 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472 		JBrowse link
G Nbn nibrin decreases expression ISO Isotretinoin results in decreased expression of NBN mRNA CTD PMID:20436886 NCBI chr 5:29,622,347...29,656,877
Ensembl chr 5:29,622,281...29,656,864 		JBrowse link
G Ndufa3 NADH:ubiquinone oxidoreductase subunit A3 decreases expression ISO Isotretinoin results in decreased expression of NDUFA3 mRNA CTD PMID:20436886 NCBI chr 1:64,172,462...64,175,174
Ensembl chr 1:64,172,540...64,175,099 		JBrowse link
G Ndufaf1 NADH:ubiquinone oxidoreductase complex assembly factor 1 decreases expression ISO Isotretinoin results in decreased expression of CIA30 mRNA CTD PMID:20436886 NCBI chr 3:111,458,227...111,469,239
Ensembl chr 3:111,458,572...111,469,518 		JBrowse link
G Ndufb3 NADH:ubiquinone oxidoreductase subunit B3 decreases expression ISO Isotretinoin results in decreased expression of NDUFB3 mRNA CTD PMID:20436886 NCBI chr 9:65,478,496...65,488,708
Ensembl chr 9:65,478,496...65,488,702 		JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 decreases expression ISO Isotretinoin results in decreased expression of NDUFC2 mRNA CTD PMID:20436886 NCBI chr 1:162,369,801...162,376,024
Ensembl chr 1:162,369,801...162,376,023 		JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 decreases expression ISO Isotretinoin results in decreased expression of NDUFS1 mRNA CTD PMID:20436886 NCBI chr 9:69,919,863...69,953,182
Ensembl chr 9:69,919,867...69,953,182 		JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 decreases expression ISO Isotretinoin results in decreased expression of NDUFS3 mRNA CTD PMID:20436886 NCBI chr 3:79,721,686...79,728,863
Ensembl chr 3:79,721,694...79,728,879 		JBrowse link
G Ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 decreases expression ISO Isotretinoin results in decreased expression of NDUFS7 mRNA CTD PMID:20436886 NCBI chr 7:12,318,776...12,326,403
Ensembl chr 7:12,318,757...12,326,392 		JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 decreases expression ISO Isotretinoin results in decreased expression of NDUFS8 mRNA CTD PMID:20436886 NCBI chr 1:219,141,289...219,144,610
Ensembl chr 1:219,141,292...219,144,610 		JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 decreases expression ISO Isotretinoin results in decreased expression of NDUFV2 mRNA CTD PMID:20436886 NCBI chr 9:113,875,718...113,900,169
Ensembl chr 9:113,875,703...113,900,190 		JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 increases expression ISO Isotretinoin results in increased expression of NEDD9 mRNA CTD PMID:15982314 NCBI chr17:22,984,792...23,179,701
Ensembl chr17:22,984,844...23,179,701 		JBrowse link
G Nefl neurofilament light decreases expression ISO Isotretinoin results in decreased expression of NEFL mRNA CTD PMID:15982314 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574 		JBrowse link
G Neurog2 neurogenin 2 increases expression ISO Isotretinoin results in increased expression of NEUROG2 mRNA CTD PMID:31711903 NCBI chr 2:231,962,517...231,963,441
Ensembl chr 2:231,962,517...231,963,308 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Isotretinoin affects the localization of and results in decreased activity of NFKB1 protein CTD PMID:18652567 PMID:19066126 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689 		JBrowse link
G Nit2 nitrilase family, member 2 decreases expression ISO Isotretinoin results in decreased expression of NIT2 mRNA CTD PMID:20436886 NCBI chr11:45,462,345...45,473,107
Ensembl chr11:45,462,345...45,473,104 		JBrowse link
G Nop16 NOP16 nucleolar protein decreases expression ISO Isotretinoin results in decreased expression of NOP16 mRNA CTD PMID:20436886 NCBI chr17:10,559,811...10,564,728
Ensembl chr17:10,559,680...10,564,733 		JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 decreases expression ISO Isotretinoin results in decreased expression of NPC1 mRNA CTD PMID:20436886 NCBI chr18:3,616,878...3,662,656
Ensembl chr18:3,616,878...3,662,683 		JBrowse link
G Npl N-acetylneuraminate pyruvate lyase decreases expression ISO Isotretinoin results in decreased expression of NPL mRNA CTD PMID:20436886 NCBI chr13:70,938,073...70,981,179
Ensembl chr13:70,938,082...70,980,913 		JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 decreases expression ISO Isotretinoin results in decreased expression of NQO2 mRNA CTD PMID:20436886 NCBI chr17:32,131,847...32,158,559
Ensembl chr17:32,132,347...32,158,538 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Isotretinoin inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]; Isotretinoin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity		 ISO [Isotretinoin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; Isotretinoin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA] CTD PMID:16632523 PMID:25455453 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545 		JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 increases expression ISO Isotretinoin results in increased expression of NR2F1 mRNA CTD PMID:20436886 NCBI chr 2:5,569,954...5,579,894
Ensembl chr 2:5,569,935...5,579,894 		JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like decreases expression ISO Isotretinoin results in decreased expression of NSDHL mRNA CTD PMID:20436886 NCBI chr  X:152,933,118...152,964,399
Ensembl chr  X:152,933,069...152,964,390 		JBrowse link
G Ntan1 N-terminal asparagine amidase decreases expression ISO Isotretinoin results in decreased expression of NTAN1 mRNA CTD PMID:20436886 NCBI chr10:3,218,414...3,235,229 JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 increases expression ISO Isotretinoin results in increased expression of NTRK2 mRNA CTD PMID:20436886 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676 		JBrowse link
G Nudt21 nudix hydrolase 21 decreases expression ISO Isotretinoin results in decreased expression of NUDT21 mRNA CTD PMID:20436886 NCBI chr19:11,451,366...11,470,637
Ensembl chr19:11,450,760...11,467,644 		JBrowse link
G Nudt4 nudix hydrolase 4 decreases expression ISO Isotretinoin results in decreased expression of NUDT4 mRNA CTD PMID:20436886 NCBI chr 7:36,643,916...36,660,334
Ensembl chr 7:36,643,916...36,660,141 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A decreases expression ISO Isotretinoin results in decreased expression of OAS1 mRNA CTD PMID:20436886 NCBI chr12:41,200,680...41,211,393
Ensembl chr12:41,200,718...41,211,909 		JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions
decreases expression		 ISO Isotretinoin inhibits the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]
Isotretinoin results in decreased expression of ODC1 mRNA		 CTD PMID:15225900 PMID:15982314 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927 		JBrowse link
G Odr4 odr-4 GPCR localization factor homolog decreases expression ISO Isotretinoin results in decreased expression of ODR4 mRNA CTD PMID:20436886 NCBI chr13:67,578,904...67,611,605
Ensembl chr13:67,583,621...67,609,469 		JBrowse link
G Olah oleoyl-ACP hydrolase decreases expression ISO Isotretinoin results in decreased expression of OLAH mRNA CTD PMID:20436886 NCBI chr17:78,878,673...78,903,919
Ensembl chr17:78,879,058...78,903,967 		JBrowse link
G Olig3 oligodendrocyte transcription factor 3 increases expression ISO Isotretinoin results in increased expression of OLIG3 mRNA CTD PMID:31711903 NCBI chr 1:14,797,766...14,799,835
Ensembl chr 1:14,797,766...14,799,835 		JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 decreases expression ISO Isotretinoin results in decreased expression of ORMDL2 mRNA CTD PMID:20436886 NCBI chr 7:3,242,991...3,246,085
Ensembl chr 7:3,242,991...3,246,071 		JBrowse link
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 decreases expression ISO Isotretinoin results in decreased expression of OTUB2 mRNA CTD PMID:20436886 NCBI chr 6:127,282,445...127,301,086
Ensembl chr 6:127,282,466...127,301,083 		JBrowse link
G Pafah2 platelet-activating factor acetylhydrolase 2 decreases expression ISO Isotretinoin results in decreased expression of PAFAH2 mRNA CTD PMID:20436886 NCBI chr 5:152,606,850...152,635,956
Ensembl chr 5:152,606,847...152,634,803 		JBrowse link
G Pank3 pantothenate kinase 3 decreases expression ISO Isotretinoin results in decreased expression of PANK3 mRNA CTD PMID:20436886 NCBI chr10:20,591,432...20,615,258
Ensembl chr10:20,591,432...20,615,258 		JBrowse link
G Paqr3 progestin and adipoQ receptor family member 3 decreases expression ISO Isotretinoin results in decreased expression of PAQR3 mRNA CTD PMID:20436886 NCBI chr14:14,107,513...14,129,780
Ensembl chr14:14,107,580...14,124,828 		JBrowse link
G Pawr pro-apoptotic WT1 regulator decreases expression ISO Isotretinoin results in decreased expression of PAWR mRNA CTD PMID:20436886 NCBI chr 7:51,273,764...51,353,700
Ensembl chr 7:51,273,771...51,353,068 		JBrowse link
G Pax6 paired box 6 increases expression ISO Isotretinoin results in increased expression of PAX6 mRNA CTD PMID:31711903 NCBI chr 3:95,700,241...95,728,682
Ensembl chr 3:95,707,386...95,728,624 		JBrowse link
G Pccb propionyl-CoA carboxylase subunit beta decreases expression ISO Isotretinoin results in decreased expression of PCCB mRNA CTD PMID:20436886 NCBI chr 8:109,368,887...109,418,871
Ensembl chr 8:109,368,624...109,418,872 		JBrowse link
G Pcdh1 protocadherin 1 multiple interactions ISO [vorinostat co-treated with Isotretinoin] results in increased expression of PCDH1 mRNA CTD PMID:18769122 NCBI chr18:31,330,081...31,343,147
Ensembl chr18:31,328,919...31,343,797 		JBrowse link
G Pcolce procollagen C-endopeptidase enhancer increases expression ISO Isotretinoin results in increased expression of PCOLCE mRNA CTD PMID:20436886 NCBI chr12:22,153,995...22,160,311
Ensembl chr12:22,153,983...22,160,337 		JBrowse link
G Pctp phosphatidylcholine transfer protein decreases expression ISO Isotretinoin results in decreased expression of PCTP mRNA CTD PMID:20436886 NCBI chr10:77,491,445...77,537,268
Ensembl chr10:77,491,454...77,512,032 		JBrowse link
G Pde6a phosphodiesterase 6A decreases expression ISO Isotretinoin results in decreased expression of PDE6A mRNA CTD PMID:20436886 NCBI chr18:56,544,652...56,617,480
Ensembl chr18:56,544,652...56,617,480 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta increases expression ISO Isotretinoin results in increased expression of PDGFRB mRNA CTD PMID:20436886 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381 		JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 decreases expression ISO Isotretinoin results in decreased expression of PDHA1 mRNA CTD PMID:20436886 NCBI chr  X:37,329,779...37,343,410
Ensembl chr  X:37,329,779...37,343,410 		JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta decreases expression ISO Isotretinoin results in decreased expression of PDHB mRNA CTD PMID:20436886 NCBI chr15:18,540,826...18,546,855
Ensembl chr15:18,539,210...18,546,854 		JBrowse link
G Pdhx pyruvate dehydrogenase complex, component X decreases expression ISO Isotretinoin results in decreased expression of PDHX mRNA CTD PMID:20436886 NCBI chr 3:92,910,300...92,933,725
Ensembl chr 3:92,909,725...92,969,050 		JBrowse link
G Pdzk1 PDZ domain containing 1 decreases expression ISO Isotretinoin results in decreased expression of PDZK1 mRNA CTD PMID:20436886 NCBI chr 2:198,965,685...198,999,323
Ensembl chr 2:198,965,685...198,999,323 		JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase decreases expression ISO Isotretinoin results in decreased expression of PECR mRNA CTD PMID:20436886 NCBI chr 9:79,601,937...79,630,547
Ensembl chr 9:79,601,901...79,630,536 		JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha decreases expression ISO Isotretinoin results in decreased expression of PEX11A mRNA CTD PMID:20436886 NCBI chr 1:141,474,189...141,481,270
Ensembl chr 1:141,474,180...141,481,315 		JBrowse link
G Pex13 peroxisomal biogenesis factor 13 decreases expression ISO Isotretinoin results in decreased expression of PEX13 mRNA CTD PMID:20436886 NCBI chr14:108,394,299...108,411,994
Ensembl chr14:108,394,303...108,412,823 		JBrowse link
G Pex16 peroxisomal biogenesis factor 16 decreases expression ISO Isotretinoin results in decreased expression of PEX16 mRNA CTD PMID:20436886 NCBI chr 3:81,283,137...81,292,575
Ensembl chr 3:81,283,137...81,292,573 		JBrowse link
G Pex19 peroxisomal biogenesis factor 19 decreases expression ISO Isotretinoin results in decreased expression of PEX19 mRNA CTD PMID:20436886 NCBI chr13:90,514,324...90,530,825
Ensembl chr13:90,514,336...90,530,349 		JBrowse link
G Pex3 peroxisomal biogenesis factor 3 decreases expression ISO Isotretinoin results in decreased expression of PEX3 mRNA CTD PMID:20436886 NCBI chr 1:7,685,209...7,726,238
Ensembl chr 1:7,685,338...7,726,401 		JBrowse link
G Pex7 peroxisomal biogenesis factor 7 decreases expression ISO Isotretinoin results in decreased expression of PEX7 mRNA CTD PMID:20436886 NCBI chr 1:15,311,768...15,374,702
Ensembl chr 1:15,311,770...15,374,850 		JBrowse link
G Pgd phosphogluconate dehydrogenase decreases expression ISO Isotretinoin results in decreased expression of PGD mRNA CTD PMID:20436886 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Pgm1 phosphoglucomutase 1 decreases expression ISO Isotretinoin results in decreased expression of PGM1 mRNA CTD PMID:20436886 NCBI chr 5:118,743,632...118,803,055
Ensembl chr 5:118,743,632...118,803,055 		JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 decreases expression ISO Isotretinoin results in decreased expression of PGRMC1 mRNA CTD PMID:20436886 NCBI chr  X:123,205,869...123,213,880
Ensembl chr  X:123,205,869...123,213,882 		JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases expression ISO Isotretinoin results in increased expression of PHGDH mRNA CTD PMID:20436886 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564 		JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 multiple interactions ISO [vorinostat co-treated with Isotretinoin] results in increased expression of PHLDA1 mRNA CTD PMID:18769122 NCBI chr 7:54,247,460...54,249,664
Ensembl chr 7:54,247,460...54,249,664 		JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 decreases expression ISO Isotretinoin results in decreased expression of PHLDA2 mRNA CTD PMID:20436886 NCBI chr 1:216,701,345...216,704,479
Ensembl chr 1:216,702,319...216,703,534 		JBrowse link
G Pik3c2g phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma decreases expression ISO Isotretinoin results in decreased expression of PIK3C2G mRNA CTD PMID:20436886 NCBI chr 4:173,732,196...174,102,502
Ensembl chr 4:173,732,248...174,102,496 		JBrowse link
G Pir pirin decreases expression
increases expression		 ISO Isotretinoin results in decreased expression of PIR mRNA
Isotretinoin results in increased expression of PIR mRNA		 CTD PMID:15982314 PMID:20436886 NCBI chr  X:31,852,322...31,968,152
Ensembl chr  X:31,852,323...31,968,152 		JBrowse link
G Pklr pyruvate kinase L/R decreases expression ISO Isotretinoin results in decreased expression of PKLR mRNA CTD PMID:20436886 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592 		JBrowse link
G Pkp1 plakophilin 1 increases expression ISO Isotretinoin results in increased expression of PKP1 mRNA CTD PMID:20436886 NCBI chr13:52,705,174...52,753,089
Ensembl chr13:52,705,174...52,752,997 		JBrowse link
G Pla2g7 phospholipase A2 group VII decreases expression ISO Isotretinoin results in decreased expression of PLA2G7 mRNA CTD PMID:20436886 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013 		JBrowse link
G Plat plasminogen activator, tissue type increases expression ISO Isotretinoin results in increased expression of PLAT mRNA CTD PMID:15982314 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889 		JBrowse link
G Plcl2 phospholipase C-like 2 increases expression ISO Isotretinoin results in increased expression of PLCL2 mRNA CTD PMID:20436886 NCBI chr 9:1,782,536...1,984,654
Ensembl chr 9:1,782,536...1,984,654 		JBrowse link
G Plin2 perilipin 2 decreases expression ISO Isotretinoin results in decreased expression of PLIN2 mRNA CTD PMID:20436886 NCBI chr 5:104,984,413...105,010,863
Ensembl chr 5:104,984,414...105,010,857 		JBrowse link
G Plpp3 phospholipid phosphatase 3 increases expression ISO Isotretinoin results in increased expression of PLPP3 mRNA CTD PMID:20436886 NCBI chr 5:124,690,214...124,765,499
Ensembl chr 5:124,690,214...124,765,498 		JBrowse link
G Pltp phospholipid transfer protein increases expression ISO Isotretinoin results in increased expression of PLTP mRNA CTD PMID:20436886 NCBI chr 3:161,304,469...161,322,289
Ensembl chr 3:161,304,469...161,322,289 		JBrowse link
G Pmel premelanosome protein decreases expression ISO Isotretinoin results in decreased expression of PMEL mRNA CTD PMID:20436886 NCBI chr 7:3,133,347...3,143,827
Ensembl chr 7:3,133,506...3,143,911 		JBrowse link
G Pmpcb peptidase, mitochondrial processing subunit beta decreases expression ISO Isotretinoin results in decreased expression of PMPCB mRNA CTD PMID:20436886 NCBI chr 4:9,908,838...9,921,615
Ensembl chr 4:9,908,831...9,921,610 		JBrowse link
G Pmvk phosphomevalonate kinase decreases expression ISO Isotretinoin results in decreased expression of PMVK mRNA CTD PMID:20436886 NCBI chr 2:188,784,329...188,793,890
Ensembl chr 2:188,784,222...188,793,895 		JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 decreases expression ISO Isotretinoin results in decreased expression of PNPLA3 mRNA CTD PMID:20436886 NCBI chr 7:125,034,760...125,056,165
Ensembl chr 7:125,034,764...125,055,976 		JBrowse link
G Polr2m RNA polymerase II subunit M increases expression ISO Isotretinoin results in increased expression of POLR2M mRNA CTD PMID:20436886 NCBI chr 8:77,985,190...77,992,621
Ensembl chr 8:77,985,190...78,096,390 		JBrowse link
G Pon3 paraoxonase 3 decreases expression ISO Isotretinoin results in decreased expression of PON3 mRNA CTD PMID:20436886 NCBI chr 4:30,311,981...30,338,679
Ensembl chr 4:30,311,982...30,338,679 		JBrowse link
G Popdc2 popeye domain containing 2 decreases expression ISO Isotretinoin results in decreased expression of POPDC2 mRNA CTD PMID:20436886 NCBI chr11:64,915,041...64,954,704
Ensembl chr11:64,936,692...64,952,687 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression EXP Isotretinoin results in increased expression of PPARG mRNA CTD PMID:19041696 PMID:19212007 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
G Ppif peptidylprolyl isomerase F decreases expression ISO Isotretinoin results in decreased expression of PPIF mRNA CTD PMID:20436886 NCBI chr16:1,979,191...1,985,912
Ensembl chr16:1,979,191...1,985,908 		JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B decreases expression ISO Isotretinoin results in decreased expression of PPM1B mRNA CTD PMID:20436886 NCBI chr 6:8,219,385...8,280,127
Ensembl chr 6:8,218,696...8,280,124 		JBrowse link
G Ppp1r16b protein phosphatase 1, regulatory subunit 16B increases expression ISO Isotretinoin results in increased expression of PPP1R16B mRNA CTD PMID:20436886 NCBI chr 3:155,160,474...155,267,002
Ensembl chr 3:155,160,481...155,262,941 		JBrowse link
G Prdx2 peroxiredoxin 2 decreases expression ISO Isotretinoin results in decreased expression of PRDX2 mRNA CTD PMID:20436886 NCBI chr19:26,084,816...26,090,095
Ensembl chr19:26,084,903...26,090,094 		JBrowse link
G Prepl prolyl endopeptidase-like decreases expression ISO Isotretinoin results in decreased expression of PREPL mRNA CTD PMID:20436886 NCBI chr 6:8,316,861...8,346,293
Ensembl chr 6:8,318,979...8,346,197 		JBrowse link
G Pros1 protein S increases expression ISO Isotretinoin results in increased expression of PROS1 mRNA CTD PMID:20436886 NCBI chr 7:1,206,648...1,288,140
Ensembl chr 7:1,206,648...1,288,134 		JBrowse link
G Prss8 serine protease 8 decreases expression ISO Isotretinoin results in decreased expression of PRSS8 mRNA CTD PMID:20436886 NCBI chr 1:199,372,519...199,377,035
Ensembl chr 1:199,372,519...199,377,035 		JBrowse link
G Psma1 proteasome 20S subunit alpha 1 decreases expression ISO Isotretinoin results in decreased expression of PSMA1 mRNA CTD PMID:20436886 NCBI chr 1:183,733,567...183,744,586
Ensembl chr 1:183,733,567...183,744,586 		JBrowse link
G Psma3 proteasome 20S subunit alpha 3 decreases expression ISO Isotretinoin results in decreased expression of PSMA3 mRNA CTD PMID:20436886 NCBI chr 6:93,423,029...93,444,223
Ensembl chr 6:93,423,002...93,444,240 		JBrowse link
G Psma4 proteasome 20S subunit alpha 4 decreases expression ISO Isotretinoin results in decreased expression of PSMA4 mRNA CTD PMID:20436886 NCBI chr 8:59,532,456...59,539,916
Ensembl chr 8:59,532,389...59,539,920 		JBrowse link
G Psma5 proteasome 20S subunit alpha 5 decreases expression ISO Isotretinoin results in decreased expression of PSMA5 mRNA CTD PMID:20436886 NCBI chr 2:211,050,344...211,073,706
Ensembl chr 2:211,050,360...211,073,714 		JBrowse link
G Psma7 proteasome 20S subunit alpha 7 decreases expression ISO Isotretinoin results in decreased expression of PSMA7 mRNA CTD PMID:20436886 NCBI chr 3:175,420,042...175,426,384
Ensembl chr 3:175,420,039...175,426,395 		JBrowse link
G Psmb5 proteasome 20S subunit beta 5 decreases expression ISO Isotretinoin results in decreased expression of PSMB5 mRNA CTD PMID:20436886 NCBI chr15:33,259,039...33,263,634
Ensembl chr15:33,259,043...33,263,659 		JBrowse link
G Ptgds prostaglandin D2 synthase increases expression ISO Isotretinoin results in increased expression of PTGDS mRNA CTD PMID:20436886 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO Isotretinoin results in decreased expression of PTGS1 mRNA CTD PMID:15982314 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Isotretinoin results in decreased expression of PTGS2 mRNA CTD PMID:15982314 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Ptprb protein tyrosine phosphatase, receptor type, B increases expression ISO Isotretinoin results in increased expression of PTPRB mRNA CTD PMID:20436886 NCBI chr 7:59,326,484...59,431,114
Ensembl chr 7:59,326,518...59,425,718 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C increases expression ISO Isotretinoin results in increased expression of PTPRC mRNA CTD PMID:20436886 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692 		JBrowse link
G Ptprg protein tyrosine phosphatase, receptor type, G increases expression ISO Isotretinoin results in increased expression of PTPRG mRNA CTD PMID:20436886 NCBI chr15:12,926,056...13,633,839
Ensembl chr15:12,926,167...13,228,607 		JBrowse link
G Ptprm protein tyrosine phosphatase, receptor type, M increases expression ISO Isotretinoin results in increased expression of PTPRM mRNA CTD PMID:20436886 NCBI chr 9:114,846,095...115,555,261
Ensembl chr 9:114,846,095...115,555,261 		JBrowse link
G Ptrh2 peptidyl-tRNA hydrolase 2 decreases expression ISO Isotretinoin results in decreased expression of PTRH2 mRNA CTD PMID:20436886 NCBI chr10:74,002,151...74,012,182
Ensembl chr10:74,002,151...74,012,159 		JBrowse link
G Pts 6-pyruvoyl-tetrahydropterin synthase decreases expression ISO Isotretinoin results in decreased expression of PTS mRNA CTD PMID:20436886 NCBI chr 8:54,954,261...54,961,271
Ensembl chr 8:54,954,226...54,961,265 		JBrowse link
G Pxmp2 peroxisomal membrane protein 2 decreases expression ISO Isotretinoin results in decreased expression of PXMP2 mRNA CTD PMID:20436886 NCBI chr12:52,452,354...52,462,655
Ensembl chr12:52,452,273...52,462,659 		JBrowse link
G Pxmp4 peroxisomal membrane protein 4 decreases expression ISO Isotretinoin results in decreased expression of PXMP4 mRNA CTD PMID:20436886 NCBI chr 3:150,091,646...150,108,893
Ensembl chr 3:150,091,630...150,108,898 		JBrowse link
G Qk quaking increases expression ISO Isotretinoin results in increased expression of QKI mRNA CTD PMID:20436886 NCBI chr 1:50,983,647...51,050,692 JBrowse link
G Rab27a RAB27A, member RAS oncogene family decreases expression ISO Isotretinoin results in decreased expression of RAB27A mRNA CTD PMID:20436886 NCBI chr 8:79,722,334...79,776,228
Ensembl chr 8:79,722,334...79,776,221 		JBrowse link
G Rab38 RAB38, member RAS oncogene family decreases expression ISO Isotretinoin results in decreased expression of RAB38 mRNA CTD PMID:20436886 NCBI chr 1:152,072,716...152,153,449
Ensembl chr 1:152,072,665...152,153,449 		JBrowse link
G Rab5if RAB5 interacting factor decreases expression ISO Isotretinoin results in decreased expression of RAB5IF mRNA CTD PMID:20436886 NCBI chr 3:152,933,771...152,943,780
Ensembl chr 3:152,933,771...152,943,777 		JBrowse link
G Rac2 Rac family small GTPase 2 increases expression ISO Isotretinoin results in increased expression of RAC2 mRNA CTD PMID:20436886 NCBI chr 7:119,769,708...119,797,111
Ensembl chr 7:119,783,849...119,797,098 		JBrowse link
G Rara retinoic acid receptor, alpha increases expression
decreases expression		 ISO
EXP		 Isotretinoin results in increased expression of RARA mRNA
Isotretinoin results in decreased expression of RARA mRNA		 CTD PMID:9262057 PMID:19041696 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210 		JBrowse link
G Rarb retinoic acid receptor, beta multiple interactions
decreases expression
increases expression		 ISO
EXP		 [LAQ824 co-treated with Isotretinoin] results in increased acetylation of RARB promoter; [LAQ824 co-treated with Isotretinoin] results in increased expression of RARB mRNA; R116010 promotes the reaction [Isotretinoin results in increased expression of RARB mRNA]
Isotretinoin results in decreased expression of RARB mRNA		 CTD PMID:17237267 PMID:17486130 PMID:19041696 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599 		JBrowse link
G Rarg retinoic acid receptor, gamma decreases expression EXP Isotretinoin results in decreased expression of RARG mRNA CTD PMID:19041696 NCBI chr 7:143,840,739...143,863,206
Ensembl chr 7:143,839,980...143,863,186 		JBrowse link
G Rarres1 retinoic acid receptor responder 1 multiple interactions
increases expression		 ISO AGN 193109 inhibits the reaction [Isotretinoin results in increased expression of RARRES1 mRNA] CTD PMID:16575387 NCBI chr 2:164,650,722...164,684,982
Ensembl chr 2:164,650,722...164,684,985 		JBrowse link
G Rasal1 RAS protein activator like 1 decreases expression ISO Isotretinoin results in decreased expression of RASAL1 mRNA CTD PMID:20436886 NCBI chr12:41,416,218...41,449,445
Ensembl chr12:41,416,218...41,448,668 		JBrowse link
G Rassf2 Ras association domain family member 2 increases expression ISO Isotretinoin results in increased expression of RASSF2 mRNA CTD PMID:20436886 NCBI chr 3:124,574,088...124,610,267
Ensembl chr 3:124,575,621...124,610,267 		JBrowse link
G Rbks ribokinase decreases expression ISO Isotretinoin results in decreased expression of RBKS mRNA CTD PMID:20436886 NCBI chr 6:26,051,568...26,128,762
Ensembl chr 6:26,051,396...26,128,906 		JBrowse link
G Rbm47 RNA binding motif protein 47 decreases expression ISO Isotretinoin results in decreased expression of RBM47 mRNA CTD PMID:20436886 NCBI chr14:43,701,944...43,839,803
Ensembl chr14:43,810,119...43,837,662 		JBrowse link
G Rbpms RNA binding protein, mRNA processing factor increases expression ISO Isotretinoin results in increased expression of RBPMS mRNA CTD PMID:20436886 NCBI chr16:61,954,569...62,109,998
Ensembl chr16:61,954,590...62,096,497 		JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 decreases expression ISO Isotretinoin results in decreased expression of RC3H2 mRNA CTD PMID:20436886 NCBI chr 3:21,621,976...21,676,789
Ensembl chr 3:21,623,041...21,670,014 		JBrowse link
G Rdh11 retinol dehydrogenase 11 decreases expression ISO Isotretinoin results in decreased expression of RDH11 mRNA CTD PMID:20436886 NCBI chr 6:102,356,498...102,372,618
Ensembl chr 6:102,356,492...102,372,611 		JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions ISO Isotretinoin affects the localization of and results in decreased activity of REL protein CTD PMID:18652567 PMID:19066126 NCBI chr14:108,490,794...108,517,582
Ensembl chr14:108,491,069...108,509,892 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Isotretinoin affects the localization of and results in decreased activity of RELA protein CTD PMID:18652567 PMID:19066126 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249 		JBrowse link
G Retreg1 reticulophagy regulator 1 decreases expression ISO Isotretinoin results in decreased expression of RETREG1 mRNA CTD PMID:20436886 NCBI chr 2:78,391,921...78,401,569
Ensembl chr 2:78,391,921...78,399,987 		JBrowse link
G Rfk riboflavin kinase decreases expression ISO Isotretinoin results in decreased expression of RFK mRNA CTD PMID:20436886 NCBI chr 1:236,494,221...236,501,733
Ensembl chr 1:236,494,221...236,501,733 		JBrowse link
G RGD1309104 similar to RIKEN cDNA 1700025G04 gene increases expression ISO Isotretinoin results in increased expression of C1ORF21 mRNA CTD PMID:20436886 NCBI chr13:69,265,649...69,434,447
Ensembl chr13:69,265,649...69,385,074 		JBrowse link
G RGD1559459 similar to Expressed sequence AI788959 decreases expression ISO Isotretinoin results in decreased expression of UGT2B28 mRNA CTD PMID:20436886 NCBI chr14:22,932,454...22,955,663
Ensembl chr14:22,937,421...22,952,822 		JBrowse link
G RGD1561113 similar to Hypothetical UPF0184 protein C9orf16 homolog decreases expression ISO Isotretinoin results in decreased expression of BBLN mRNA CTD PMID:20436886 NCBI chr 3:11,408,076...11,410,907
Ensembl chr 3:11,408,348...11,410,732 		JBrowse link
G Rhoa ras homolog family member A decreases expression ISO Isotretinoin results in decreased expression of RHOA mRNA CTD PMID:15982314 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167 		JBrowse link
G Rhob ras homolog family member B decreases expression ISO Isotretinoin results in decreased expression of RHOB mRNA CTD PMID:15982314 NCBI chr 6:33,689,127...33,691,301
Ensembl chr 6:33,689,127...33,691,301 		JBrowse link
G Rhobtb3 Rho-related BTB domain containing 3 increases expression ISO Isotretinoin results in increased expression of RHOBTB3 mRNA CTD PMID:20436886 NCBI chr 2:2,627,655...2,683,305
Ensembl chr 2:2,627,393...2,683,116 		JBrowse link
G Rida reactive intermediate imine deaminase A homolog decreases expression ISO Isotretinoin results in decreased expression of UK114 mRNA CTD PMID:20436886 NCBI chr 7:73,256,506...73,270,308
Ensembl chr 7:73,256,508...73,270,308 		JBrowse link
G Riox2 ribosomal oxygenase 2 decreases expression ISO Isotretinoin results in decreased expression of RIOX2 mRNA CTD PMID:20436886 NCBI chr11:43,006,190...43,028,722
Ensembl chr11:43,006,757...43,022,565 		JBrowse link
G Rmdn1 regulator of microtubule dynamics 1 decreases expression ISO Isotretinoin results in decreased expression of RMDN1 mRNA CTD PMID:20436886 NCBI chr 5:33,580,891...33,604,564
Ensembl chr 5:33,580,944...33,638,165 		JBrowse link
G Rnaset2 ribonuclease T2 increases expression ISO Isotretinoin results in increased expression of RNASET2 mRNA CTD PMID:20436886 NCBI chr 1:53,174,879...53,192,048
Ensembl chr 1:53,174,879...53,192,048 		JBrowse link
G Rnd3 Rho family GTPase 3 decreases expression ISO Isotretinoin results in decreased expression of RND3 mRNA CTD PMID:20436886 NCBI chr 3:36,643,374...36,660,727
Ensembl chr 3:36,642,587...36,660,758 		JBrowse link
G Rnf128 ring finger protein 128 decreases expression ISO Isotretinoin results in decreased expression of RNF128 mRNA CTD PMID:20436886 NCBI chr  X:110,789,061...110,877,964
Ensembl chr  X:110,789,269...110,877,978 		JBrowse link
G Rnf38 ring finger protein 38 increases expression ISO Isotretinoin results in increased expression of RNF38 mRNA CTD PMID:20436886 NCBI chr 5:59,604,783...59,713,108
Ensembl chr 5:59,607,476...59,647,633 		JBrowse link
G Rnf5 ring finger protein 5 decreases expression ISO Isotretinoin results in decreased expression of RNF5 mRNA CTD PMID:15982314 NCBI chr20:4,366,244...4,368,690
Ensembl chr20:4,366,246...4,368,693 		JBrowse link
G Ro60 Ro60, Y RNA binding protein decreases expression ISO Isotretinoin results in decreased expression of RO60 mRNA CTD PMID:20436886 NCBI chr13:60,546,892...60,567,882
Ensembl chr13:60,546,912...60,567,882 		JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 increases expression ISO Isotretinoin results in increased expression of ROR1 mRNA CTD PMID:20436886 NCBI chr 5:118,892,874...119,239,528
Ensembl chr 5:119,097,715...119,241,733 		JBrowse link
G Rora RAR-related orphan receptor A decreases expression ISO Isotretinoin results in decreased expression of RORA mRNA CTD PMID:20436886 NCBI chr 8:75,515,886...75,616,477
Ensembl chr 8:75,516,904...75,607,212 		JBrowse link
G Rpe65 retinoid isomerohydrolase RPE65 multiple interactions ISO
EXP		 [Isotretinoin binds to and results in decreased activity of RPE65 protein] which results in decreased abundance of Retinaldehyde CTD PMID:16411761 NCBI chr 2:266,141,581...266,169,197
Ensembl chr 2:266,141,581...266,169,197 		JBrowse link
G Rpp40 ribonuclease P/MRP subunit p40 decreases expression ISO Isotretinoin results in decreased expression of RPP40 mRNA CTD PMID:20436886 NCBI chr17:29,638,647...29,647,709
Ensembl chr17:29,638,677...29,647,763 		JBrowse link
G RT1-Bb RT1 class II, locus Bb increases expression ISO Isotretinoin results in increased expression of HLA-DQB1 mRNA CTD PMID:20436886 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 increases expression ISO Isotretinoin results in increased expression of HLA-F mRNA CTD PMID:20436886 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991 		JBrowse link
G RT1-Ha RT1 class II, locus Ha increases expression ISO Isotretinoin results in increased expression of HLA-DPA1 mRNA CTD PMID:20436886 NCBI chr20:3,875,478...3,885,140
Ensembl chr20:3,875,706...3,881,461 		JBrowse link
G RT1-S3 RT1 class Ib, locus S3 increases expression ISO Isotretinoin results in increased expression of HLA-E mRNA CTD PMID:20436886 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818 		JBrowse link
G Rtca RNA 3'-terminal phosphate cyclase decreases expression ISO Isotretinoin results in decreased expression of RTCA mRNA CTD PMID:20436886 NCBI chr 2:219,537,213...219,558,489
Ensembl chr 2:219,537,206...219,558,675 		JBrowse link
G Rtn1 reticulon 1 increases expression ISO Isotretinoin results in increased expression of RTN1 mRNA CTD PMID:20436886 NCBI chr 6:94,951,016...95,177,477
Ensembl chr 6:94,951,020...95,061,174 		JBrowse link
G Rxra retinoid X receptor alpha multiple interactions
affects binding
increases activity		 ISO
EXP		 Isotretinoin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]
Isotretinoin binds to RXRA protein
Isotretinoin results in increased activity of RXRA protein		 CTD PMID:16632523 PMID:21543282 PMID:31566444 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908 		JBrowse link
G Rxrb retinoid X receptor beta decreases expression EXP Isotretinoin results in decreased expression of RXRB mRNA CTD PMID:19041696 NCBI chr20:3,822,673...3,829,138
Ensembl chr20:3,823,042...3,829,140 		JBrowse link
G S100a1 S100 calcium binding protein A1 decreases expression ISO Isotretinoin results in decreased expression of S100A1 mRNA CTD PMID:15982314 NCBI chr 2:189,900,505...189,905,348
Ensembl chr 2:189,900,667...189,903,219 		JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression ISO Isotretinoin results in increased expression of S100A4 mRNA CTD PMID:20436886 NCBI chr 2:189,997,278...189,999,587
Ensembl chr 2:189,997,129...189,999,604 		JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO Isotretinoin results in increased expression of S100A8 mRNA CTD PMID:15982314 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354 		JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO Isotretinoin results in increased expression of S100A9 mRNA CTD PMID:15982314 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276 		JBrowse link
G Samm50 SAMM50 sorting and assembly machinery component decreases expression ISO Isotretinoin results in decreased expression of SAMM50 mRNA CTD PMID:20436886 NCBI chr 7:125,058,966...125,082,506
Ensembl chr 7:125,058,897...125,082,505 		JBrowse link
G Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 increases expression ISO Isotretinoin results in increased expression of SAMSN1 mRNA CTD PMID:20436886 NCBI chr11:14,252,088...14,405,825
Ensembl chr11:14,253,848...14,304,725 		JBrowse link
G Sar1b secretion associated, Ras related GTPase 1B decreases expression ISO Isotretinoin results in decreased expression of SAR1B mRNA CTD PMID:20436886 NCBI chr10:37,215,989...37,245,603
Ensembl chr10:37,215,937...37,245,658 		JBrowse link
G Sc5d sterol-C5-desaturase decreases expression ISO Isotretinoin results in decreased expression of SC5D mRNA CTD PMID:20436886 NCBI chr 8:46,525,406...46,537,014
Ensembl chr 8:46,525,400...46,537,050 		JBrowse link
G Scamp1 secretory carrier membrane protein 1 decreases expression ISO Isotretinoin results in decreased expression of SCAMP1 mRNA CTD PMID:20436886 NCBI chr 2:23,858,021...23,941,128
Ensembl chr 2:23,857,995...23,941,084 		JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha increases expression ISO Isotretinoin results in increased expression of SCNN1A mRNA CTD PMID:18769122 NCBI chr 4:157,834,339...157,860,472
Ensembl chr 4:157,836,912...157,860,049 		JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 decreases expression ISO Isotretinoin results in decreased expression of SDF2L1 mRNA CTD PMID:20436886 NCBI chr11:88,122,271...88,124,513
Ensembl chr11:88,122,271...88,124,513 		JBrowse link
G Sdhc succinate dehydrogenase complex subunit C decreases expression ISO Isotretinoin results in decreased expression of SDHC mRNA CTD PMID:20436886 NCBI chr13:89,498,047...89,518,979
Ensembl chr13:89,498,048...89,518,939 		JBrowse link
G Selplg selectin P ligand increases expression ISO Isotretinoin results in increased expression of SELPLG mRNA CTD PMID:20436886 NCBI chr12:48,577,905...48,579,196
Ensembl chr12:48,577,905...48,579,196 		JBrowse link
G Septin11 septin 11 decreases expression ISO Isotretinoin results in decreased expression of SEPTIN11 mRNA CTD PMID:20436886 NCBI chr14:16,369,544...16,405,645
Ensembl chr14:16,369,544...16,452,998 		JBrowse link
G Serhl2 serine hydrolase-like 2 increases expression ISO Isotretinoin results in increased expression of SERHL2 mRNA CTD PMID:20436886 NCBI chr 7:123,963,381...123,990,103
Ensembl chr 7:123,963,381...123,990,103 		JBrowse link
G Serpinb2 serpin family B member 2 decreases expression ISO Isotretinoin results in decreased expression of SERPINB2 mRNA CTD PMID:15982314 NCBI chr13:27,449,907...27,463,015
Ensembl chr13:27,449,934...27,463,010 		JBrowse link
G Serpinb8 serpin family B member 8 decreases expression ISO Isotretinoin results in decreased expression of SERPINB8 mRNA CTD PMID:15982314 NCBI chr13:27,876,662...27,914,038
Ensembl chr13:27,889,345...27,914,006 		JBrowse link
G Serpinb9 serpin family B member 9 decreases expression ISO Isotretinoin results in decreased expression of SERPINB9 mRNA CTD PMID:15982314 NCBI chr17:32,648,846...32,673,047
Ensembl chr17:32,650,441...32,661,865 		JBrowse link
G Serpine1 serpin family E member 1 decreases expression EXP Isotretinoin results in decreased expression of SERPINE1 mRNA CTD PMID:15972972 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482 		JBrowse link
G Serping1 serpin family G member 1 increases expression ISO Isotretinoin results in increased expression of SERPING1 mRNA CTD PMID:20436886 NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078 		JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 decreases expression ISO Isotretinoin results in decreased expression of SGK2 mRNA CTD PMID:20436886 NCBI chr 3:159,361,313...159,385,843
Ensembl chr 3:159,368,273...159,384,775 		JBrowse link
G Shh sonic hedgehog signaling molecule increases expression ISO Isotretinoin results in increased expression of SHH mRNA CTD PMID:26096596 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 decreases expression ISO Isotretinoin results in decreased expression of SHMT1 mRNA CTD PMID:20436886 NCBI chr10:47,030,813...47,059,216
Ensembl chr10:47,031,050...47,059,216 		JBrowse link
G Sirpa signal-regulatory protein alpha increases expression ISO Isotretinoin results in increased expression of SIRPA mRNA CTD PMID:20436886 NCBI chr 3:122,113,735...122,152,478
Ensembl chr 3:122,114,108...122,152,477 		JBrowse link
G Sla src-like adaptor increases expression ISO Isotretinoin results in increased expression of SLA mRNA CTD PMID:20436886 NCBI chr 7:107,585,055...107,604,950
Ensembl chr 7:107,584,118...107,634,335 		JBrowse link
G Slc11a2 solute carrier family 11 member 2 decreases expression ISO Isotretinoin results in decreased expression of SLC11A2 mRNA CTD PMID:20436886 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212 		JBrowse link
G Slc15a1 solute carrier family 15 member 1 decreases expression ISO Isotretinoin results in decreased expression of SLC15A1 mRNA CTD PMID:20436886 NCBI chr15:106,800,081...106,844,668
Ensembl chr15:106,800,081...106,844,426 		JBrowse link
G Slc16a1 solute carrier family 16 member 1 decreases expression ISO Isotretinoin results in decreased expression of SLC16A1 mRNA CTD PMID:15982314 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554 		JBrowse link
G Slc16a7 solute carrier family 16 member 7 decreases expression ISO Isotretinoin results in decreased expression of SLC16A7 mRNA CTD PMID:20436886 NCBI chr 7:68,438,341...68,606,312
Ensembl chr 7:68,446,193...68,549,763 		JBrowse link
G Slc22a18 solute carrier family 22, member 18 decreases expression ISO Isotretinoin results in decreased expression of SLC22A18 mRNA CTD PMID:20436886 NCBI chr 1:216,676,330...216,700,632
Ensembl chr 1:216,677,373...216,700,641 		JBrowse link
G Slc25a11 solute carrier family 25 member 11 decreases expression ISO Isotretinoin results in decreased expression of SLC25A11 mRNA CTD PMID:20436886 NCBI chr10:57,265,903...57,268,018
Ensembl chr10:57,265,704...57,268,081 		JBrowse link
G Slc25a15 solute carrier family 25 member 15 decreases expression ISO Isotretinoin results in decreased expression of SLC25A15 mRNA CTD PMID:20436886 NCBI chr16:74,505,318...74,554,523
Ensembl chr16:74,531,564...74,554,529 		JBrowse link
G Slc25a16 solute carrier family 25 member 16 decreases expression ISO Isotretinoin results in decreased expression of SLC25A16 mRNA CTD PMID:20436886 NCBI chr20:27,283,383...27,308,069
Ensembl chr20:27,254,984...27,308,069 		JBrowse link
G Slc25a17 solute carrier family 25 member 17 decreases expression ISO Isotretinoin results in decreased expression of SLC25A17 mRNA CTD PMID:20436886 NCBI chr 7:122,539,293...122,581,777
Ensembl chr 7:122,539,293...122,581,777 		JBrowse link
G Slc26a3 solute carrier family 26 member 3 decreases expression ISO Isotretinoin results in decreased expression of SLC26A3 mRNA CTD PMID:20436886 NCBI chr 6:50,725,085...50,766,306
Ensembl chr 6:50,725,085...50,766,300 		JBrowse link
G Slc27a2 solute carrier family 27 member 2 decreases expression ISO Isotretinoin results in decreased expression of SLC27A2 mRNA CTD PMID:20436886 NCBI chr 3:119,014,620...119,052,531
Ensembl chr 3:119,014,620...119,052,531 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression EXP Isotretinoin results in increased expression of SLC2A4 mRNA CTD PMID:19212007 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487 		JBrowse link
G Slc30a1 solute carrier family 30 member 1 decreases expression ISO Isotretinoin results in decreased expression of SLC30A1 mRNA CTD PMID:20436886 NCBI chr13:110,677,810...110,681,683
Ensembl chr13:110,677,810...110,681,683 		JBrowse link
G Slc30a10 solute carrier family 30, member 10 decreases expression ISO Isotretinoin results in decreased expression of SLC30A10 mRNA CTD PMID:20436886 NCBI chr13:103,396,295...103,406,759
Ensembl chr13:103,396,314...103,410,363 		JBrowse link
G Slc31a1 solute carrier family 31 member 1 decreases expression ISO Isotretinoin results in decreased expression of SLC31A1 mRNA CTD PMID:20436886 NCBI chr 5:78,222,504...78,249,358
Ensembl chr 5:78,222,504...78,249,358 		JBrowse link
G Slc35a2 solute carrier family 35 member A2 decreases expression ISO Isotretinoin results in decreased expression of SLC35A2 mRNA CTD PMID:20436886 NCBI chr  X:15,453,184...15,461,990
Ensembl chr  X:15,453,186...15,461,713 		JBrowse link
G Slc35b1 solute carrier family 35, member B1 decreases expression ISO Isotretinoin results in decreased expression of SLC35B1 mRNA CTD PMID:20436886 NCBI chr10:83,201,532...83,208,605
Ensembl chr10:83,201,311...83,208,605 		JBrowse link
G Slc39a14 solute carrier family 39 member 14 increases expression ISO Isotretinoin results in increased expression of SLC39A14 mRNA CTD PMID:20436886 NCBI chr15:51,982,872...52,029,841
Ensembl chr15:51,982,982...52,029,816 		JBrowse link
G Slc39a8 solute carrier family 39 member 8 decreases expression ISO Isotretinoin results in decreased expression of SLC39A8 mRNA CTD PMID:20436886 NCBI chr 2:241,028,851...241,092,584
Ensembl chr 2:241,029,693...241,092,582 		JBrowse link
G Slc46a3 solute carrier family 46, member 3 decreases expression ISO Isotretinoin results in decreased expression of SLC46A3 mRNA CTD PMID:20436886 NCBI chr12:8,725,479...8,741,944
Ensembl chr12:8,725,517...8,741,951 		JBrowse link
G Slc50a1 solute carrier family 50 member 1 decreases expression ISO Isotretinoin results in decreased expression of SLC50A1 mRNA CTD PMID:20436886 NCBI chr 2:188,585,118...188,587,498
Ensembl chr 2:188,585,118...188,587,498 		JBrowse link
G Slc5a6 solute carrier family 5 member 6 decreases expression ISO Isotretinoin results in decreased expression of SLC5A6 mRNA CTD PMID:20436886 NCBI chr 6:26,685,823...26,697,110
Ensembl chr 6:26,686,033...26,697,116 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 decreases expression ISO Isotretinoin results in decreased expression of SLC7A5 mRNA CTD PMID:20436886 NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563 		JBrowse link
G Slco4c1 solute carrier organic anion transporter family, member 4C1 decreases expression ISO Isotretinoin results in decreased expression of SLCO4C1 mRNA CTD PMID:20436886 NCBI chr 9:104,301,935...104,350,262
Ensembl chr 9:104,299,277...104,350,308 		JBrowse link
G Slit3 slit guidance ligand 3 increases expression ISO Isotretinoin results in increased expression of SLIT3 mRNA CTD PMID:20436886 NCBI chr10:19,924,200...20,517,918
Ensembl chr10:20,320,878...20,518,518 		JBrowse link
G Smyd3 SET and MYND domain containing 3 increases expression ISO Isotretinoin results in increased expression of SMYD3 mRNA CTD PMID:20436886 NCBI chr13:97,330,120...97,807,813 JBrowse link
G Sned1 sushi, nidogen and EGF-like domains 1 increases expression ISO Isotretinoin results in increased expression of SNED1 mRNA CTD PMID:20436886 NCBI chr 9:100,380,487...100,439,125
Ensembl chr 9:100,380,515...100,437,056 		JBrowse link
G Snx13 sorting nexin 13 decreases expression ISO Isotretinoin results in decreased expression of SNX13 mRNA CTD PMID:20436886 NCBI chr 6:54,487,626...54,591,716
Ensembl chr 6:54,488,038...54,588,778 		JBrowse link
G Soat1 sterol O-acyltransferase 1 decreases expression ISO Isotretinoin results in decreased expression of SOAT1 mRNA CTD PMID:20436886 NCBI chr13:74,035,258...74,077,759
Ensembl chr13:74,035,080...74,077,783 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 decreases expression ISO Isotretinoin results in decreased expression of SOCS1 mRNA CTD PMID:15982314 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461 		JBrowse link
G Socs2 suppressor of cytokine signaling 2 increases expression ISO Isotretinoin results in increased expression of SOCS2 mRNA CTD PMID:15982314 NCBI chr 7:36,495,496...36,500,878
Ensembl chr 7:36,495,480...36,499,784 		JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO Isotretinoin results in decreased expression of SOD2 mRNA CTD PMID:20436886 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587 		JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 decreases expression ISO Isotretinoin results in decreased expression of SORBS1 mRNA CTD PMID:20436886 NCBI chr 1:259,373,921...259,502,108
Ensembl chr 1:259,376,933...259,484,569 		JBrowse link
G Sord sorbitol dehydrogenase decreases expression ISO Isotretinoin results in decreased expression of SORD mRNA CTD PMID:20436886 NCBI chr 3:114,176,127...114,207,368
Ensembl chr 3:114,176,309...114,207,366 		JBrowse link
G Sort1 sortilin 1 decreases expression ISO Isotretinoin results in decreased expression of SORT1 mRNA CTD PMID:20436886 NCBI chr 2:211,078,092...211,156,312
Ensembl chr 2:211,078,334...211,156,312 		JBrowse link
G Sox17 SRY-box transcription factor 17 decreases localization ISO Isotretinoin results in decreased localization of SOX17 protein CTD PMID:24154490 NCBI chr 5:14,890,318...14,895,907
Ensembl chr 5:14,890,408...14,895,907 		JBrowse link
G Spcs3 signal peptidase complex subunit 3 decreases expression ISO Isotretinoin results in decreased expression of SPCS3 mRNA CTD PMID:20436886 NCBI chr16:40,050,862...40,056,296
Ensembl chr16:40,050,734...40,058,822 		JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO Isotretinoin results in increased expression of SPP1 mRNA CTD PMID:18769122 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901 		JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 increases expression ISO Isotretinoin results in increased expression of SPRED2 mRNA CTD PMID:20436886 NCBI chr14:104,268,362...104,290,206
Ensembl chr14:104,191,517...104,290,456 		JBrowse link
G Sprr1b small proline-rich protein 1B increases expression ISO Isotretinoin results in increased expression of SPRR1B mRNA CTD PMID:15982314 NCBI chr 2:192,622,972...192,624,848
Ensembl chr 2:192,623,244...192,623,681 		JBrowse link
G Sprr3 small proline-rich protein 3 decreases expression ISO Isotretinoin results in decreased expression of SPRR3 mRNA CTD PMID:18769122 NCBI chr 2:192,641,472...192,643,942
Ensembl chr 2:192,641,790...192,642,548 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases expression ISO Isotretinoin results in decreased expression of SRD5A1 mRNA CTD PMID:20436886 NCBI chr 1:36,320,504...36,354,694
Ensembl chr 1:36,320,461...36,354,756 		JBrowse link
G Srpx2 sushi-repeat-containing protein, X-linked 2 decreases expression ISO Isotretinoin results in decreased expression of SRPX2 mRNA CTD PMID:20436886 NCBI chr  X:104,734,035...104,760,658
Ensembl chr  X:104,734,082...104,760,547 		JBrowse link
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 decreases expression ISO Isotretinoin results in decreased expression of ST6GALNAC4 mRNA CTD PMID:20436886 NCBI chr 3:11,607,103...11,619,595
Ensembl chr 3:11,607,225...11,619,593 		JBrowse link
G Stambp Stam binding protein decreases expression ISO Isotretinoin results in decreased expression of STAMBP mRNA CTD PMID:20436886 NCBI chr 4:115,249,343...115,277,340
Ensembl chr 4:115,249,351...115,275,068 		JBrowse link
G Stap2 signal transducing adaptor family member 2 decreases expression ISO Isotretinoin results in decreased expression of STAP2 mRNA CTD PMID:20436886 NCBI chr 9:11,064,605...11,070,138
Ensembl chr 9:11,064,605...11,070,122 		JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression ISO Isotretinoin results in decreased expression of STIP1 mRNA CTD PMID:18769122 NCBI chr 1:222,274,133...222,293,139
Ensembl chr 1:222,274,133...222,293,148 		JBrowse link
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha decreases expression ISO Isotretinoin results in decreased expression of SUCLG1 mRNA CTD PMID:20436886 NCBI chr 4:101,181,315...101,210,692
Ensembl chr 4:101,180,404...101,210,746 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases expression ISO Isotretinoin results in increased expression of SULT2A1 mRNA CTD PMID:15982314 NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230 		JBrowse link
G Susd5 sushi domain containing 5 increases expression ISO Isotretinoin results in increased expression of SUSD5 mRNA CTD PMID:20436886 NCBI chr 8:122,331,489...122,370,684
Ensembl chr 8:122,331,583...122,368,368 		JBrowse link
G Syn2 synapsin II decreases expression ISO Isotretinoin results in decreased expression of SYN2 mRNA CTD PMID:20436886 NCBI chr 4:147,037,179...147,195,096
Ensembl chr 4:147,037,179...147,195,096 		JBrowse link
G Syngr1 synaptogyrin 1 decreases expression ISO Isotretinoin results in decreased expression of SYNGR1 mRNA CTD PMID:20436886 NCBI chr 7:121,311,008...121,334,437
Ensembl chr 7:121,311,024...121,334,437 		JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 increases expression ISO Isotretinoin results in increased expression of TACSTD2 mRNA CTD PMID:15982314 NCBI chr 4:98,341,187...98,342,887
Ensembl chr 4:98,341,188...98,342,887 		JBrowse link
G Tagln transgelin increases expression
multiple interactions		 ISO Isotretinoin results in increased expression of TAGLN mRNA
[LAQ824 co-treated with Isotretinoin] results in increased expression of TAGLN mRNA		 CTD PMID:17237267 NCBI chr 8:50,222,895...50,228,369
Ensembl chr 8:50,222,896...50,231,357 		JBrowse link
G Tagln3 transgelin 3 decreases expression ISO Isotretinoin results in decreased expression of TAGLN3 mRNA CTD PMID:20436886 NCBI chr11:60,072,983...60,086,552
Ensembl chr11:60,072,727...60,086,553 		JBrowse link
G Taldo1 transaldolase 1 decreases expression ISO Isotretinoin results in decreased expression of TALDO1 mRNA CTD PMID:20436886 NCBI chr 1:214,375,555...214,385,886
Ensembl chr 1:214,375,515...214,385,885 		JBrowse link
G Tbc1d1 TBC1 domain family member 1 increases expression ISO Isotretinoin results in increased expression of TBC1D1 mRNA CTD PMID:20436886 NCBI chr14:45,598,753...45,797,650
Ensembl chr14:45,598,743...45,797,887 		JBrowse link
G Tbl1xr1 TBL1X receptor 1 increases expression ISO Isotretinoin results in increased expression of TBL1XR1 mRNA CTD PMID:20436886 NCBI chr 2:107,221,913...107,359,229
Ensembl chr 2:107,233,054...107,359,229 		JBrowse link
G Tcf15 transcription factor 15 decreases expression ISO Isotretinoin results in decreased expression of TCF15 mRNA CTD PMID:31711903 NCBI chr 3:147,643,250...147,649,511
Ensembl chr 3:147,643,250...147,649,504 		JBrowse link
G Tcta T-cell leukemia translocation altered decreases expression ISO Isotretinoin results in decreased expression of TCTA mRNA CTD PMID:20436886 NCBI chr 8:117,079,094...117,082,338
Ensembl chr 8:117,079,095...117,082,162 		JBrowse link
G Tecr trans-2,3-enoyl-CoA reductase decreases expression ISO Isotretinoin results in decreased expression of TECR mRNA CTD PMID:20436886 NCBI chr19:24,705,478...24,732,024
Ensembl chr19:24,705,481...24,732,024 		JBrowse link
G Tent5c terminal nucleotidyltransferase 5C decreases expression ISO Isotretinoin results in decreased expression of TENT5C mRNA CTD PMID:20436886 NCBI chr 2:202,797,766...202,816,562
Ensembl chr 2:202,798,198...202,816,562 		JBrowse link
G Tert telomerase reverse transcriptase decreases expression ISO Isotretinoin results in decreased expression of TERT mRNA CTD PMID:16180984 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476 		JBrowse link
G Tfdp2 transcription factor Dp-2 decreases expression ISO Isotretinoin results in decreased expression of TFDP2 mRNA CTD PMID:20436886 NCBI chr 8:104,040,795...104,181,228
Ensembl chr 8:104,040,934...104,176,446 		JBrowse link
G Tff2 trefoil factor 2 decreases expression ISO Isotretinoin results in decreased expression of TFF2 mRNA CTD PMID:20436886 NCBI chr20:9,872,669...9,876,008
Ensembl chr20:9,872,680...9,876,008 		JBrowse link
G Tfrc transferrin receptor decreases expression ISO Isotretinoin results in decreased expression of TFRC mRNA CTD PMID:20436886 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression EXP Isotretinoin results in decreased expression of TGFB1 mRNA CTD PMID:15972972 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 increases expression ISO Isotretinoin results in increased expression of TGFB1I1 mRNA CTD PMID:15982314 NCBI chr 1:199,664,039...199,670,970
Ensembl chr 1:199,664,173...199,670,961 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 increases expression ISO Isotretinoin results in increased expression of TGFBR2 mRNA CTD PMID:20436886 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494 		JBrowse link
G Tgm1 transglutaminase 1 decreases expression ISO Isotretinoin results in decreased expression of TGM1 mRNA CTD PMID:15982314 NCBI chr15:34,378,136...34,393,150
Ensembl chr15:34,378,148...34,392,066 		JBrowse link
G Thbs1 thrombospondin 1 decreases expression ISO Isotretinoin results in decreased expression of THBS1 mRNA CTD PMID:15982314 PMID:18769122 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466 		JBrowse link
G Thbs4 thrombospondin 4 increases expression ISO Isotretinoin results in increased expression of THBS4 mRNA CTD PMID:20436886 NCBI chr 2:22,343,727...22,385,855
Ensembl chr 2:22,343,727...22,385,855 		JBrowse link
G Thra thyroid hormone receptor alpha decreases expression EXP Isotretinoin results in decreased expression of THRA mRNA CTD PMID:19041696 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933 		JBrowse link
G Thrb thyroid hormone receptor beta decreases expression EXP Isotretinoin results in decreased expression of THRB mRNA CTD PMID:19041696 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282 		JBrowse link
G Timm13 translocase of inner mitochondrial membrane 13 decreases expression ISO Isotretinoin results in decreased expression of TIMM13 mRNA CTD PMID:20436886 NCBI chr 7:11,677,340...11,678,443
Ensembl chr 7:11,677,340...11,678,442 		JBrowse link
G Timm23 translocase of inner mitochondrial membrane 23 decreases expression ISO Isotretinoin results in decreased expression of TIMM23 mRNA CTD PMID:20436886 NCBI chr16:8,324,038...8,350,067
Ensembl chr16:8,324,036...8,350,067 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 increases expression ISO Isotretinoin results in increased expression of TIMP3 mRNA CTD PMID:20436886 NCBI chr 7:23,543,125...23,594,170
Ensembl chr 7:23,544,215...23,594,133 		JBrowse link
G Tjp3 tight junction protein 3 increases expression ISO Isotretinoin results in increased expression of TJP3 mRNA CTD PMID:18769122 NCBI chr 7:11,295,892...11,314,535
Ensembl chr 7:11,295,892...11,315,615 		JBrowse link
G Tkt transketolase decreases expression ISO Isotretinoin results in decreased expression of TKT mRNA CTD PMID:20436886 NCBI chr16:6,609,670...6,634,608
Ensembl chr16:6,609,668...6,634,595 		JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 decreases expression ISO Isotretinoin results in decreased expression of TM7SF2 mRNA CTD