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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:valproate
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Accession:CHEBI:60654 term browser browse the term
Definition:A branched-chain saturated fatty acid anion that is the conjugate base of valproic acid.
Synonyms:exact_synonym: 2-propylpentanoate
 related_synonym: 2-propylvalerate;   Formula=C8H15O2;   InChI=1S/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)/p-1;   InChIKey=NIJJYAXOARWZEE-UHFFFAOYSA-M;   SMILES=CCCC(CCC)C([O-])=O;   dipropylacetate
 alt_id: CHEBI:68615
 xref: LINCS:LSM-6363;   PMID:16012283;   PMID:20633966;   PMID:21161183;   PMID:21167688;   PMID:21243535;   PMID:21454832;   PMID:21459656;   PMID:21472635;   PMID:21593515;   PMID:21629819;   PMID:21767635;   PMID:8681902
 cyclic_relationship: is_conjugate_base_of CHEBI:39867


show annotations for term's descendants           Sort by:
 
sodium valproate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac8 histone deacetylase 8 decreases activity EXP Sodium valproate attenuates the reaction [deoxycorticosterone acetate increases activity of Hdac8 protein in the heart] RGD PMID:23868068 RGD:9681716 NCBI chr  X:72,163,777...72,370,058
Ensembl chr  X:72,163,777...72,370,044
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19767
    role 19714
      biological role 19714
        biochemical role 19303
          metabolite 19285
            eukaryotic metabolite 18958
              plant metabolite 17453
                valerate 1
                  valproate 1
                    sodium valproate + 1
                    valproyl-CoA(4-) 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19767
    subatomic particle 19766
      composite particle 19766
        hadron 19766
          baryon 19766
            nucleon 19766
              atomic nucleus 19766
                atom 19766
                  main group element atom 19657
                    p-block element atom 19657
                      carbon group element atom 19573
                        carbon atom 19563
                          organic molecular entity 19563
                            organic ion 8455
                              organic anion 3037
                                carboxylic acid anion 2398
                                  monocarboxylic acid anion 1499
                                    fatty acid anion 103
                                      saturated fatty acid anion 102
                                        straight-chain saturated fatty acid anion 8
                                          valerate 1
                                            valproate 1
                                              sodium valproate + 1
                                              valproyl-CoA(4-) 0
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