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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:NMDA receptor antagonist
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Accession:CHEBI:60643 term browser browse the term
Definition:Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs.
Synonyms:related_synonym: N-methyl-D-aspartate receptor antagonist;   N-methyl-D-aspartate receptor antagonists;   NMDA receptor antagonists;   NMDAR antagonist;   NMDAR antagonists
 alt_id: CHEBI:60797


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  CHEBI ontology 0
    role 0
      biological role 0
        pharmacological role 0
          antagonist 0
            excitatory amino acid antagonist 0
              NMDA receptor antagonist 0
                (1R,2S)-nortilidine + 0
                (R)-ketamine 0
                (R,R)-tramadol + 0
                (R,R)-tramadol hydrochloride + 0
                (S,S)-tramadol + 0
                (S,S)-tramadol hydrochloride + 0
                2-amino-5-phosphonopentanoic acid 0
                7-chlorokynurenic acid 0
                CGP 78608 0
                CGP 78608 hydrochloride 0
                N-[2-(4-phenoxybenzyl)benzimidazol-5-yl]methanesulfonamide 0
                N-\{2-[(4-benzylpiperidin-1-yl)methyl]benzimidazol-5-yl\}methanesulfonamide 0
                amantadine 0
                amantadine hydrochloride 0
                amantadine sulfate 0
                dextromethadone + 0
                dextromethorphan + 0
                dinitrogen oxide 0
                dizocilpine 0
                dizocilpine maleate 0
                eliprodil 0
                esketamine + 0
                esketamine hydrochloride 0
                ethanol + 0
                ginsenoside Rb3 0
                isoliquiritigenin + 0
                ketamine + 0
                ketamine hydrochloride + 0
                kynurenic acid + 0
                levomethadone + 0
                memantine 0
                memantine hydrochloride 0
                methadone + 0
                noribogaine 0
                orphenadrine + 0
                orphenadrine citrate 0
                orphenadrine hydrochloride 0
                pentamidine 0
                phencyclidine 0
                rolicyclidine 0
                tenocyclidine 0
                tramadol 0
                tramadol hydrochloride 0
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