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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:metalaxyl-M
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Accession:CHEBI:60607 term browser browse the term
Definition:A methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)alaninate that is the more active R-enantiomer of metalaxyl. A systemic fungicide, it is active against phytopathogens of the order Peronosporales and is used to conrtrol Pythium in a number of vegetable crops.
Synonyms:exact_synonym: methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)-D-alaninate
 related_synonym: (-)-metalaxyl;   (R)-N-(2,6-dimethylphenyl)-N-(methoxyacetylamino)propionic acid methyl ester;   Formula=C15H21NO4;   InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1;   InChIKey=ZQEIXNIJLIKNTD-GFCCVEGCSA-N;   R-metalaxyl;   SMILES=COCC(=O)N([C@H](C)C(=O)OC)c1c(C)cccc1C;   mefenoxam;   methyl (R)-2-{[(2,6-dimethylphenyl)methoxyacetyl]amino} propionate;   methyl (R)-N-(2,6-dimethylphenyl)-N-(methoxyacetyl)alaninate;   methyl N-(methoxyacetyl)-N-(2,6-xylyl)-D-alaninate
 xref: AGR:IND44452872;   CAS:70630-17-0;   KEGG:C18626;   PMID:19809773;   PMID:20582630;   PMID:21174493;   PMID:21272886;   PMID:21315406;   PMID:21322247;   PMID:21712597;   PPDB:445;   Patent:WO2011012493;   Pesticides:metalaxyl-m;   Reaxys:5081553
 cyclic_relationship: is_enantiomer_of CHEBI:82791


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metalaxyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 decreases expression EXP metalaxyl results in decreased expression of CYP2C19 protein CTD PMID:32194361 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 decreases expression EXP metalaxyl results in decreased expression of CYP7A1 protein CTD PMID:32194361 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163 		JBrowse link
G S100P S100 calcium binding protein P increases expression EXP metalaxyl results in increased expression of S100P protein CTD PMID:32194361 NCBI chr 4:6,693,878...6,697,170
Ensembl chr 4:6,693,878...6,697,170 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26034
    role 25961
      application 25172
        agrochemical 17514
          metalaxyl-M 3
            metalaxyl 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 26034
    subatomic particle 26009
      composite particle 26009
        hadron 26020
          baryon 26009
            nucleon 26009
              atomic nucleus 26009
                atom 26009
                  main group element atom 25834
                    p-block element atom 25834
                      carbon group element atom 25434
                        carbon atom 25403
                          organic molecular entity 25392
                            heteroorganic entity 24766
                              organochalcogen compound 24378
                                organooxygen compound 24054
                                  carbon oxoacid 22749
                                    carboxylic acid 22729
                                      monocarboxylic acid 21724
                                        fatty acid 18997
                                          saturated fatty acid 18699
                                            propionic acid 4404
                                              alanine 116
                                                alanine derivative 114
                                                  methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)alaninate 3
                                                    metalaxyl-M 3
                                                      metalaxyl 3
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