The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Tramadol affects the activity of CASP3 protein Vitamin E inhibits the reaction [Tramadol results in increased expression of CASP3 protein] Tramadol results in decreased activity of CASP3 protein
Tramadol results in decreased expression of CAT mRNA; Tramadol results in decreased expression of CAT protein Tramadol deficiency inhibits the reaction [Tramadol results in increased expression of CAT mRNA]
Tramadol results in decreased expression of CKB mRNA Ethanol promotes the reaction [Tramadol results in increased expression of [CKM protein binds to CKB protein]]; Tramadol promotes the reaction [Ethanol results in increased expression of [CKM protein binds to CKB protein]]; Tramadol results in increased expression of [CKM protein binds to CKB protein]
Ethanol promotes the reaction [Tramadol results in increased expression of [CKM protein binds to CKB protein]]; Tramadol promotes the reaction [Ethanol results in increased expression of [CKM protein binds to CKB protein]]; Tramadol results in increased expression of [CKM protein binds to CKB protein]
CYP2D6 gene mutant form affects the metabolism of Tramadol; CYP2D6 gene polymorphism affects the metabolism of Tramadol CYP2D6 protein affects the methylation of Tramadol [CYP2D6 protein results in increased metabolism of and results in increased activity of Tramadol] which results in increased chemical synthesis of O-demethyltramadol; CYP2D6 gene polymorphism affects the metabolism of and affects the susceptibility to Tramadol; CYP2D6 protein results in increased metabolism of and results in increased activity of Tramadol CYP2D6 protein results in decreased methylation of Tramadol CYP2D6 affects the susceptibility to Tramadol; CYP2D6 gene polymorphism affects the susceptibility to Tramadol; CYP2D6 protein affects the susceptibility to Tramadol CYP2D6 gene polymorphism results in decreased susceptibility to Tramadol CYP2D6 gene mutant form results in increased susceptibility to Tramadol CYP2D6 gene mutant form results in increased metabolism of Tramadol; CYP2D6 protein results in increased metabolism of Tramadol
Tramadol results in increased activity of HTR2A protein Tramadol results in increased expression of HTR2A mRNA Ketanserin inhibits the reaction [Tramadol results in increased activity of HTR2A protein]
Tramadol binds to OPRD1 protein [Tramadol binds to OPRD1 protein] which results in decreased uptake of Norepinephrine; [Tramadol binds to OPRD1 protein] which results in decreased uptake of Serotonin
Tramadol binds to OPRK1 protein [Tramadol binds to OPRK1 protein] which results in decreased uptake of Norepinephrine; [Tramadol binds to OPRK1 protein] which results in decreased uptake of Serotonin
Tramadol binds to OPRM1 protein [Tramadol binds to OPRM1 protein] which results in decreased uptake of Norepinephrine; [Tramadol binds to OPRM1 protein] which results in decreased uptake of Serotonin
Naloxone inhibits the reaction [Tramadol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]]; Tramadol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Tramadol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]
Tramadol results in decreased expression of SOD1 mRNA; Tramadol results in decreased expression of SOD1 protein Tramadol deficiency inhibits the reaction [Tramadol results in increased expression of SOD1 mRNA]
Tramadol deficiency inhibits the reaction [Tramadol results in increased expression of SOD2 mRNA] Tramadol results in decreased expression of SOD2 mRNA
Ethanol promotes the reaction [Tramadol results in increased expression of SPP1 protein]; Tramadol promotes the reaction [Ethanol results in increased expression of SPP1 protein]
[Acetaminophen co-treated with Tramadol] inhibits the reaction [Freund's Adjuvant results in increased expression of TNF protein]; Tramadol promotes the reaction [Ethanol results in increased expression of TNF protein]; Vitamin E inhibits the reaction [Tramadol results in increased expression of TNF protein]
Ethanol promotes the reaction [Tramadol results in increased expression of TNNI3 protein]; Tramadol promotes the reaction [Ethanol results in increased expression of TNNI3 protein]
ACHE protein results in increased chemical synthesis of 6-O-monoacetylmorphine [ACHE protein results in increased degradation of 6-O-monoacetylmorphine] which results in increased chemical synthesis of Morphine; [ACHE protein results in increased metabolism of Heroin] which results in increased chemical synthesis of 6-O-monoacetylmorphine
[BCHE protein results in increased degradation of 6-O-monoacetylmorphine] which results in increased chemical synthesis of Morphine; [BCHE protein results in increased metabolism of Heroin] which results in increased chemical synthesis of 6-O-monoacetylmorphine BCHE protein results in increased chemical synthesis of 6-O-monoacetylmorphine
6-O-monoacetylmorphine binds to CES1 protein Cocaine inhibits the reaction [CES1 protein results in increased chemical synthesis of 6-O-monoacetylmorphine]
CES2 protein results in increased hydrolysis of 6-O-monoacetylmorphine Cocaine inhibits the reaction [CES2 protein results in increased chemical synthesis of 6-O-monoacetylmorphine]; Cocaine inhibits the reaction [CES2 protein results in increased hydrolysis of 6-O-monoacetylmorphine]
CYB5A protein promotes the reaction [CYP3A4 protein affects the metabolism of Alfentanil]; CYB5A protein promotes the reaction [CYP3A5 protein affects the metabolism of Alfentanil]
CYB5A protein promotes the reaction [CYP3A5 protein affects the metabolism of Alfentanil]; Ketoconazole inhibits the reaction [CYP3A5 protein affects the metabolism of Alfentanil]; Troleandomycin inhibits the reaction [CYP3A5 protein affects the metabolism of Alfentanil]
Buprenorphine results in decreased activity of CAT protein [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Buprenorphine] results in increased activity of CAT protein
CYP3A4 protein affects the metabolism of Buprenorphine CYP3A4 protein results in decreased alkylation of Buprenorphine CYP3A4 protein results in increased metabolism of Buprenorphine Buprenorphine results in decreased activity of CYP3A4 protein
Buprenorphine binds to and affects the activity of OPRM1 protein; Buprenorphine binds to and results in increased activity of OPRM1 protein; Buprenorphine inhibits the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein] Buprenorphine binds to OPRM1 protein
CYP2D6 protein affects the metabolism of Codeine; CYP2D6 protein polymorphism affects the metabolism of Codeine [CYP2D6 gene mutant form results in increased activity of CYP2D6 protein] which results in increased susceptibility to Codeine; [CYP2D6 protein results in increased metabolism of Codeine] which results in increased chemical synthesis of Morphine [CYP2D22 protein results in increased metabolism of Codeine] which results in increased chemical synthesis of norcodeine CYP2D6 protein polymorphism affects the susceptibility to Codeine CYP2D6 protein results in decreased methylation of Codeine CYP2D6 gene polymorphism results in increased metabolism of Codeine; CYP2D6 protein results in increased metabolism of Codeine
CYP3A4 protein affects the metabolism of Codeine CYP3A4 protein results in increased metabolism of Codeine [CYP3A4 protein results in increased metabolism of Codeine] which results in increased chemical synthesis of norcodeine
Endocannabinoids inhibits the reaction [Enkephalin, Leucine-2-Alanine binds to and results in increased activity of OPRD1 protein]; Enkephalin, Leucine-2-Alanine binds to and results in increased activity of OPRD1 protein
Enkephalin, Leucine-2-Alanine inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; Naltrexone inhibits the reaction [Enkephalin, Leucine-2-Alanine inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]]
[Dextropropoxyphene binds to OPRD1 protein] which results in decreased uptake of Norepinephrine; [Dextropropoxyphene binds to OPRD1 protein] which results in decreased uptake of Serotonin
[Dextropropoxyphene binds to OPRK1 protein] which results in decreased uptake of Norepinephrine; [Dextropropoxyphene binds to OPRK1 protein] which results in decreased uptake of Serotonin
[Dextropropoxyphene binds to OPRM1 protein] which results in decreased uptake of Norepinephrine; [Dextropropoxyphene binds to OPRM1 protein] which results in decreased uptake of Serotonin
[Enkephalin, D-Penicillamine (2,5)- binds to and results in increased activity of OPRD1 protein] which results in decreased abundance of Aluminum; [Enkephalin, D-Penicillamine (2,5)- binds to and results in increased activity of OPRD1 protein] which results in increased susceptibility to Cocaine; naltrindole inhibits the reaction [[Enkephalin, D-Penicillamine (2,5)- binds to and results in increased activity of OPRD1 protein] which results in increased susceptibility to Cocaine] 7-hydroxymitragynine affects the reaction [Enkephalin, D-Penicillamine (2,5)- binds to and results in increased activity of OPRD1 protein]; Buprenorphine inhibits the reaction [Enkephalin, D-Penicillamine (2,5)- analog binds to OPRD1 protein]; Enkephalin, D-Penicillamine (2,5)- binds to and results in increased activity of OPRD1 protein Enkephalin, D-Penicillamine (2,5)- binds to OPRD1 protein Enkephalin, D-Penicillamine (2,5)- results in increased expression of OPRD1 mRNA
[etonitazene analog binds to and results in increased activity of OPRM1 protein] which results in increased activity of ARRB2 protein; [etonitazene binds to and results in increased activity of OPRM1 protein] which results in increased activity of ARRB2 protein
etonitazene results in increased phosphorylation of OPRM1 protein [etonitazene analog binds to and results in increased activity of OPRM1 protein] which results in increased activity of ARRB2 protein; [etonitazene binds to and results in increased activity of OPRM1 protein] which results in increased activity of ARRB2 protein; etonitazene analog binds to and results in increased activity of OPRM1 protein; etonitazene binds to and results in increased activity of OPRM1 protein
ABCB1 protein results in increased transport of Fentanyl tariquidar inhibits the reaction [ABCB1 protein results in increased transport of Fentanyl] ABCB1 protein results in increased susceptibility to Fentanyl
Fentanyl affects the localization of ARRB2 protein [Fentanyl binds to and results in increased activity of OPRM1 protein] which results in increased activity of ARRB2 protein
Fentanyl inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]; Naloxone inhibits the reaction [Fentanyl inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]]
Fentanyl results in increased phosphorylation of OPRM1 protein [Fentanyl binds to and results in increased activity of OPRM1 protein] which results in increased activity of ARRB2 protein; Fentanyl binds to and results in increased activity of OPRM1 protein
Fentanyl results in decreased expression of POMC protein alternative form [Fentanyl co-treated with Morphine] results in decreased expression of POMC protein alternative form
Heroin results in decreased expression of BDNF protein Heroin results in decreased expression of BDNF mRNA Heroin inhibits the reaction [CREB1 protein modified form binds to BDNF promoter]
[Heroin co-treated with Cocaine] results in increased activity of CASP3 protein; Heroin promotes the reaction [Cocaine results in increased activity of CASP3 protein]
CES1 protein results in decreased acetylation of Heroin CES1 protein results in increased hydrolysis of Heroin Cocaine inhibits the reaction [CES1 protein results in increased hydrolysis of Heroin] Heroin binds to CES1 protein
Heroin results in increased expression of CNR1 mRNA; Heroin results in increased expression of CNR1 protein Cannabidiol inhibits the reaction [Heroin results in increased expression of CNR1 mRNA]; Cannabidiol inhibits the reaction [Heroin results in increased expression of CNR1 protein]
Heroin results in increased expression of FOS mRNA; Heroin results in increased expression of FOS protein Dronabinol affects the reaction [Heroin results in increased expression of FOS protein]
Cannabidiol inhibits the reaction [Heroin results in decreased expression of GRM5 mRNA]; Cannabidiol inhibits the reaction [Heroin results in decreased expression of GRM5 protein] Heroin results in decreased expression of GRM5 mRNA; Heroin results in decreased expression of GRM5 protein
hydrocodone bitartrate decreases expression of Slc7a11 protein in nucleus accumbens and hippocampus Ceftriaxone inhibits the reaction [hydrocodone bitartrate decreases expression of Slc7a11 protein in nucleus accumbens and hippocampus]
Hydromorphone results in increased activity of OPRM1 protein [Hydromorphone binds to and results in increased activity of OPRM1 protein] which results in increased activity of ARRB2 protein; Hydromorphone binds to and results in increased activity of OPRM1 protein
DPP3 protein results in increased cleavage of Enkephalin, Leucine spinorphin inhibits the reaction [DPP3 protein results in increased cleavage of Enkephalin, Leucine]; tynorphin inhibits the reaction [DPP3 protein results in increased cleavage of Enkephalin, Leucine]
Loperamide binds to ABCB1 protein Loperamide results in decreased expression of ABCB1 mRNA Loperamide inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA] ABCB1 protein results in increased transport of Loperamide ABCB1A protein affects the susceptibility to Loperamide
Loperamide results in decreased expression of ANO1 mRNA; Loperamide results in decreased expression of ANO1 protein Foeniculum vulgare fruit inhibits the reaction [Loperamide results in decreased expression of ANO1 mRNA]; Foeniculum vulgare fruit inhibits the reaction [Loperamide results in decreased expression of ANO1 protein]; mosapride inhibits the reaction [Loperamide results in decreased expression of ANO1 mRNA]; mosapride inhibits the reaction [Loperamide results in decreased expression of ANO1 protein]
Loperamide results in increased expression of CDKN1A mRNA Loperamide promotes the reaction [Doxorubicin results in increased expression of CDKN1A mRNA]
Loperamide results in decreased activity of CES2 protein [Loperamide results in decreased activity of CES2 protein] which results in increased susceptibility to Bisphenol A-Glycidyl Methacrylate
Foeniculum vulgare fruit inhibits the reaction [Loperamide results in decreased expression of HTR4 mRNA]; mosapride inhibits the reaction [Loperamide results in decreased expression of HTR4 mRNA]
Loperamide results in decreased expression of MYLK mRNA Foeniculum vulgare fruit inhibits the reaction [Loperamide results in decreased expression of MYLK mRNA]; mosapride inhibits the reaction [Loperamide results in decreased expression of MYLK mRNA]
Foeniculum vulgare fruit inhibits the reaction [Loperamide results in decreased expression of NOS1 protein]; mosapride inhibits the reaction [Loperamide results in decreased expression of NOS1 protein]
[Loperamide co-treated with PK 11195] results in decreased activity of NR1I3 protein alternative form; Loperamide binds to and results in decreased activity of NR1I3 protein alternative form
Loperamide results in decreased expression of RYR3 mRNA Foeniculum vulgare fruit inhibits the reaction [Loperamide results in decreased expression of RYR3 mRNA]; mosapride inhibits the reaction [Loperamide results in decreased expression of RYR3 mRNA]
Aminoglutethimide inhibits the reaction [CYP19A1 protein affects the metabolism of Methadone]; formestane inhibits the reaction [CYP19A1 protein affects the metabolism of Methadone]
Methadone results in increased expression of IL4 mRNA; Methadone results in increased expression of IL4 protein CTAP octapeptide inhibits the reaction [Methadone results in increased expression of IL4 mRNA]; SB 203580 inhibits the reaction [Methadone results in increased expression of IL4 mRNA]
Methadone results in increased expression of IL6 mRNA; Methadone results in increased expression of IL6 protein Methadone results in increased secretion of IL6 protein
Methadone binds to OPRD1 protein [Methadone binds to OPRD1 protein] which results in decreased uptake of Norepinephrine; [Methadone binds to OPRD1 protein] which results in decreased uptake of Serotonin
Methadone binds to OPRK1 protein [Methadone binds to OPRK1 protein] which results in decreased uptake of Norepinephrine; [Methadone binds to OPRK1 protein] which results in decreased uptake of Serotonin
[Methadone binds to OPRM1 protein] which results in decreased uptake of Norepinephrine; [Methadone binds to OPRM1 protein] which results in decreased uptake of Serotonin
Methadone affects the secretion of PRL protein Methadone results in increased secretion of PRL protein Methadone results in increased expression of PRL protein
Methadone binds to TLR4 protein Methadone results in increased expression of TLR4 mRNA; Methadone results in increased expression of TLR4 protein Methadone affects the susceptibility to TLR4 protein Naloxone affects the reaction [Methadone binds to TLR4 protein]
Morphine results in decreased expression of ACAT1 protein Morphine deficiency affects the reaction [Morphine results in decreased expression of ACAT1 protein]
[ACHE protein results in increased degradation of 6-O-monoacetylmorphine] which results in increased chemical synthesis of Morphine ACHE protein results in increased chemical synthesis of Morphine
ADCY8 protein affects the susceptibility to Morphine Morphine affects the expression of ADCY8 mRNA [ADCY8 protein co-treated with ADCY1 protein] affects the susceptibility to Morphine
ADORA1 protein affects the susceptibility to Morphine Morphine results in increased expression of ADORA1 mRNA; Morphine results in increased expression of ADORA1 protein [lead acetate co-treated with Morphine] results in increased expression of ADORA1 mRNA; [lead acetate co-treated with Morphine] results in increased expression of ADORA1 protein
[lead acetate co-treated with Morphine] results in increased expression of AIF1 mRNA corilagin inhibits the reaction [Morphine results in increased expression of AIF1 protein]; Minocycline inhibits the reaction [Morphine results in increased expression of AIF1 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of AIF1 protein]]; Tunicamycin inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of AIF1 protein]]
ARRB2 protein inhibits the reaction [Morphine results in decreased expression of AKT1 protein modified form] Morphine results in increased expression of AKT1 protein modified form Naloxone inhibits the reaction [Morphine results in increased expression of AKT1 protein modified form]
Morphine results in increased expression of APOE protein Morphine deficiency affects the reaction [Morphine results in increased expression of APOE protein]
morphine increases expression in Arc protein in nucleus accumbens morphine increases expression of Arc mRNA in prefrontal cortex morphine co-treated with naloxone increases expression of Arc protein in brain Morphine increases expression of Arc protein in shell of nucleus accumbens
ARL6IP5 mutant form inhibits the reaction [Morphine results in increased expression of OPRD1 protein]; ARL6IP5 mutant form inhibits the reaction [Morphine results in increased phosphorylation of MAPK1 protein]; ARL6IP5 mutant form inhibits the reaction [Morphine results in increased phosphorylation of MAPK3 protein]; ARL6IP5 mutant form inhibits the reaction [Morphine results in increased phosphorylation of PPP1R1B protein]; Morphine promotes the reaction [ARL6IP5 protein binds to OPRD1 protein] Morphine results in increased expression of ARL6IP5 protein ARL6IP5 mutant form inhibits the reaction [Morphine results in increased expression of OPRD1 protein]; ARL6IP5 mutant form inhibits the reaction [Morphine results in increased phosphorylation of MAPK1 protein]; ARL6IP5 mutant form inhibits the reaction [Morphine results in increased phosphorylation of MAPK3 protein]; ARL6IP5 mutant form inhibits the reaction [Morphine results in increased phosphorylation of PPP1R1B protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ARL6IP5 mutant form inhibits the reaction [Morphine results in increased expression of OPRD1 protein]]; Morphine promotes the reaction [ARL6IP5 protein binds to OPRD1 protein]
ARRB2 gene SNP affects the susceptibility to Morphine [Morphine binds to and results in increased activity of OPRM1 protein] which results in increased activity of ARRB2 protein ARRB2 protein affects the susceptibility to Morphine [gp120 protein, Human immunodeficiency virus 1 co-treated with Morphine] results in decreased expression of ARRB2 mRNA; [OPRM1 protein co-treated with Morphine] results in increased activity of ARRB2 protein; ARRB2 protein inhibits the reaction [Morphine results in decreased expression of AKT1 protein modified form]; ARRB2 protein inhibits the reaction [Morphine results in decreased expression of CASP8 protein alternative form]
Morphine deficiency affects the reaction [Morphine deficiency affects the reaction [Morphine results in increased expression of ART3 protein]]; Morphine deficiency affects the reaction [Morphine results in increased expression of ART3 protein]
corilagin inhibits the reaction [Morphine results in increased expression of ATF4 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of ATF4 protein]]
[[Morphine results in increased expression of BAX protein] co-treated with [Morphine results in decreased expression of BCL2 protein]] results in increased activity of CASP3 protein; [Morphine results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of BAX protein; Morphine inhibits the reaction [Dactinomycin results in increased expression of BAX protein]; Morphine inhibits the reaction [Doxorubicin results in increased expression of BAX protein]; Naloxone inhibits the reaction [Morphine inhibits the reaction [Dactinomycin results in increased expression of BAX protein]]; PDGFB protein inhibits the reaction [Morphine results in increased expression of BAX protein] Morphine results in increased expression of BAX mRNA; Morphine results in increased expression of BAX protein Morphine results in decreased expression of BAX mRNA epigallocatechin gallate inhibits the reaction [Morphine results in increased expression of BAX protein]; Lithium inhibits the reaction [Morphine results in increased expression of BAX mRNA] TGFB1 protein affects the reaction [Morphine results in increased expression of BAX protein]
BCHE protein results in increased chemical synthesis of Morphine [BCHE protein results in increased degradation of 6-O-monoacetylmorphine] which results in increased chemical synthesis of Morphine
[[Morphine results in increased expression of BAX protein] co-treated with [Morphine results in decreased expression of BCL2 protein]] results in increased activity of CASP3 protein; Morphine inhibits the reaction [BECN1 protein binds to BCL2 protein]; Morphine inhibits the reaction [Dactinomycin results in decreased expression of BCL2 protein]; Morphine inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]; Naloxone inhibits the reaction [Morphine inhibits the reaction [Dactinomycin results in decreased expression of BCL2 protein]]; PDGFB protein inhibits the reaction [Morphine results in decreased expression of BCL2 protein] Morphine results in decreased expression of BCL2 mRNA; Morphine results in decreased expression of BCL2 protein epigallocatechin gallate inhibits the reaction [Morphine results in decreased expression of BCL2 protein]; Lithium inhibits the reaction [Morphine results in decreased expression of BCL2 mRNA]
Morphine results in increased expression of BDNF mRNA; Morphine results in increased expression of BDNF protein Morphine increases expression of Bdnf mRNA in ventral tegmental area Morphine results in decreased expression of BDNF mRNA; Morphine results in decreased expression of BDNF mRNA alternative form Morphine inhibits the reaction [CREB1 protein modified form binds to BDNF promoter]; Morphine inhibits the reaction [NR4A2 protein binds to BDNF promoter]; Morphine inhibits the reaction [RING1 protein alternative form binds to BDNF promoter]; Morphine promotes the reaction [CREB1 protein binds to BDNF promoter]; Morphine promotes the reaction [EZH2 protein binds to BDNF promoter]; Morphine promotes the reaction [ING2 protein binds to BDNF promoter]; Morphine promotes the reaction [KMT2A protein binds to BDNF promoter]; Morphine promotes the reaction [SIN3A protein binds to BDNF promoter]; Morphine promotes the reaction [SUZ12 protein binds to BDNF promoter] AM 251 inhibits the reaction [Morphine results in increased expression of BDNF protein]; BDNF protein inhibits the reaction [NR4A2 protein affects the susceptibility to Morphine]; Curcumin inhibits the reaction [Morphine results in increased expression of BDNF mRNA]
Morphine results in increased expression of CALCA mRNA; Morphine results in increased expression of CALCA protein PENK protein alternative form inhibits the reaction [Morphine results in increased expression of CALCA protein] GRIK1 protein affects the reaction [Morphine results in increased expression of CALCA protein]
[[Morphine results in increased expression of BAX protein] co-treated with [Morphine results in decreased expression of BCL2 protein]] results in increased activity of CASP3 protein; Morphine inhibits the reaction [Doxorubicin results in increased cleavage of and results in increased activity of CASP3 protein]; Morphine results in increased activity of and results in increased cleavage of CASP3 protein; PDGFB protein inhibits the reaction [Morphine results in increased activity of CASP3 protein] Morphine results in increased cleavage of CASP3 protein Morphine results in increased expression of CASP3 protein epigallocatechin gallate inhibits the reaction [Morphine results in increased cleavage of CASP3 protein]; Minocycline inhibits the reaction [Morphine results in increased activity of CASP3 protein] corilagin inhibits the reaction [Morphine results in increased cleavage of CASP3 protein]; Minocycline inhibits the reaction [Morphine results in increased cleavage of CASP3 protein]; Naloxone inhibits the reaction [Morphine results in increased activity of CASP3 protein]; Naloxone inhibits the reaction [Morphine results in increased expression of CASP3 protein alternative form]; SB 203580 inhibits the reaction [Morphine results in increased activity of CASP3 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased cleavage of CASP3 protein]]; Tunicamycin inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased cleavage of CASP3 protein]] Morphine results in increased expression of CASP3 protein; Morphine results in increased expression of CASP3 protein alternative form
ARRB2 protein inhibits the reaction [Morphine results in decreased expression of CASP8 protein alternative form] Morphine results in increased activity of CASP8 protein
beta-funaltrexamine inhibits the reaction [Morphine results in decreased expression of CCL5 protein]; Naloxone inhibits the reaction [Morphine results in decreased expression of CCL5 protein]
[Morphine results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of CDKN1A protein
CES2 protein results in increased chemical synthesis of Morphine Cocaine inhibits the reaction [CES2 protein results in increased chemical synthesis of Morphine]
[Morphine results in increased expression of CNR1 mRNA] which results in increased susceptibility to Dronabinol; Morphine inhibits the reaction [TNF protein results in increased expression of CNR1 mRNA] Morphine deficiency results in decreased expression of CNR1 mRNA CTAP octapeptide inhibits the reaction [Morphine inhibits the reaction [TNF protein results in increased expression of CNR1 mRNA]]; Cycloheximide inhibits the reaction [Morphine inhibits the reaction [TNF protein results in increased expression of CNR1 mRNA]]; Morphine inhibits the reaction [TNF protein results in increased expression of CNR1 mRNA]
Morphine results in decreased expression of CREB1 mRNA morphine decreases phosphorylation of Creb1 protein in prefrontal cortex morphine increases phosphorylation of Creb protein in Cortical cell AM 251 inhibits the reaction [Morphine results in increased phosphorylation of CREB1 protein]; suvorexant inhibits the reaction [Morphine results in increased expression of CREB1 protein] Morphine inhibits the reaction [CREB1 protein modified form binds to BDNF promoter]; Morphine inhibits the reaction [CREB1 protein modified form binds to NR4A2 promoter]; Morphine promotes the reaction [CREB1 protein binds to BDNF promoter]; Morphine promotes the reaction [CREB1 protein modified form binds to GRIA1 promoter]; Morphine promotes the reaction [CREB1 protein modified form binds to TH promoter] Morphine results in decreased phosphorylation of CREB1 protein
[CP 154526 binds to and results in decreased activity of CRHR1 protein] inhibits the reaction [Morphine deficiency affects the abundance of Norepinephrine]; [CP 154526 binds to and results in decreased activity of CRHR1 protein] inhibits the reaction [Morphine deficiency results in increased phosphorylation of MAPK1 protein]; [CP 154526 binds to and results in decreased activity of CRHR1 protein] inhibits the reaction [Morphine deficiency results in increased phosphorylation of MAPK3 protein]; [CP 154526 binds to and results in decreased activity of CRHR1 protein] inhibits the reaction [Morphine deficiency results in increased phosphorylation of TH protein]; [CP 154526 binds to and results in decreased activity of CRHR1 protein] inhibits the reaction [Morphine deficiency results in increased secretion of POMC protein modified form]; [CP 154526 binds to and results in decreased activity of CRHR1 protein] which results in decreased susceptibility to Morphine deficiency CRHR1 gene mutant form inhibits the reaction [[Morphine co-treated with Naloxone] results in increased phosphorylation of TH protein]
Morphine results in increased secretion of CYCS protein Morphine results in decreased secretion of CYCS protein Morphine inhibits the reaction [Doxorubicin affects the localization of CYCS protein]
CYP2D6 protein affects the chemical synthesis of Morphine Morphine results in increased activity of CYP2D6 protein [CYP2D6 protein results in increased metabolism of Codeine] which results in increased chemical synthesis of Morphine
Morphine deficiency affects the reaction [Morphine deficiency affects the reaction [Morphine results in increased expression of DDAH2 protein]]; Morphine deficiency affects the reaction [Morphine results in increased expression of DDAH2 protein]
corilagin inhibits the reaction [Morphine results in increased expression of DDIT3 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of DDIT3 protein]]
Morphine results in decreased expression of DLG4 mRNA; Morphine results in decreased expression of DLG4 protein Morphine results in increased expression of [GRIN1 protein binds to GRIN2B protein binds to DLG4 protein]; resveratrol inhibits the reaction [Morphine results in increased expression of [GRIN1 protein binds to GRIN2B protein binds to DLG4 protein]] Morphine results in increased expression of DLG4 mRNA
Morphine results in decreased expression of DRD2 mRNA Morphine deficiency results in decreased expression of DRD2 mRNA [lead acetate co-treated with Morphine] results in increased expression of DRD2 mRNA; [lead acetate co-treated with Morphine] results in increased expression of DRD2 protein DRD2 protein affects the susceptibility to Morphine Morphine results in increased expression of DRD2 mRNA
Morphine deficiency results in increased expression of EGR1 mRNA; Morphine results in increased expression of EGR1 mRNA Morphine increases expression of Egr1 mRNA in ventral tegmental area and prefrontal cortex
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Morphine results in increased expression of EGR4 mRNA]; [Morphine results in increased activity of ELK1 protein] which results in increased expression of EGR4 mRNA EGR4 protein affects the susceptibility to Morphine
corilagin inhibits the reaction [Morphine results in increased phosphorylation of EIF2AK3 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased phosphorylation of EIF2AK3 protein]]
ELK1 protein affects the susceptibility to Morphine Morphine results in increased activity of ELK1 protein [Morphine results in increased activity of ELK1 protein] which results in increased expression of EGR4 mRNA
Morphine results in increased expression of F2 protein Morphine deficiency affects the reaction [Morphine results in increased expression of F2 protein]
[FAS protein binds to FASL protein] affects the reaction [Morphine results in increased expression of IL4 protein] [Morphine results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of FAS protein Morphine results in increased expression of FAS mRNA
[FAS protein binds to FASL protein] affects the reaction [Morphine results in increased expression of IL4 protein] Morphine results in increased expression of FASL mRNA
Morphine results in increased expression of FBLIM1 protein Morphine deficiency affects the reaction [Morphine results in increased expression of FBLIM1 protein]
Morphine results in decreased secretion of FGF2 protein Naloxone inhibits the reaction [Morphine results in decreased secretion of FGF2 protein]; OPRM1 protein affects the reaction [Morphine results in decreased secretion of FGF2 protein]
Morphine deficiency inhibits the reaction [Morphine deficiency inhibits the reaction [Morphine results in decreased expression of FHL2 protein]]; Morphine deficiency inhibits the reaction [Morphine results in decreased expression of FHL2 protein]
[Morphine co-treated with Dehydroepiandrosterone Sulfate] results in decreased expression of FOS protein; [Morphine co-treated with Dizocilpine Maleate] inhibits the reaction [Naloxone results in increased expression of FOS protein]; Plant Extracts inhibits the reaction [Morphine results in increased expression of FOS protein] Morphine deficiency affects the expression of FOS protein Morphine results in increased expression of FOS mRNA; Morphine results in increased expression of FOS protein Morphine affects the expression of FOS mRNA 1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea inhibits the reaction [[Morphine co-treated with Naloxone] results in increased expression of FOS protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Morphine results in increased expression of FOS protein]; [Morphine co-treated with Cocaine] affects the expression of FOS; [Morphine co-treated with N-Methyl-3,4-methylenedioxyamphetamine] affects the expression of FOS; [Morphine co-treated with Naloxone] results in increased expression of FOS protein; [Naloxone co-treated with Morphine] results in increased expression of FOS protein; [SCH772984 co-treated with bilobalide] inhibits the reaction [Oxaliplatin promotes the reaction [Morphine results in increased expression of FOS protein]]; bilobalide inhibits the reaction [Oxaliplatin promotes the reaction [Morphine results in increased expression of FOS protein]]; Genistein inhibits the reaction [Morphine results in increased expression of FOS protein]; Morphine affects the reaction [Formaldehyde results in increased expression of FOS protein]; N-(5-(3-dimethylaminobenzamido)-2-methylphenyl)-4-hydroxybenzamide inhibits the reaction [Morphine results in increased expression of FOS protein]; Oxaliplatin promotes the reaction [Morphine results in increased expression of FOS protein]; SCH772984 inhibits the reaction [Oxaliplatin promotes the reaction [Morphine results in increased expression of FOS protein]]; U 0126 inhibits the reaction [Morphine results in increased expression of FOS protein]
Agmatine inhibits the reaction [Morphine results in increased expression of FOSB protein] morphine increases expression of Fosb protein in nucleus accumbens and caudate-putamen morphine increases expression of FosB mRNA in striatum morphine increases expression of Fosb protein in the Brainstem morphine increases expression of Fosb protein in brain Morphine results in increased expression of FOSB mRNA Morphine results in increased expression of FOSB mRNA; Morphine results in increased expression of FOSB protein; Morphine results in increased expression of FOSB protein alternative form; Morphine results in increased expression of FOSB protein modified form
Morphine results in decreased expression of GNAI2 mRNA Morphine promotes the reaction [GNAI2 protein binds to RGS17 protein] Morphine results in increased expression of GNAI2 mRNA
GRIA1 protein affects the susceptibility to Morphine Morphine increases localization of Gria1 protein on shell of nucleus accumbens cell surface Morphine increases expression of Gria protein in the nucleus accumbens Morphine increases localization of Gria1 protein on nucleus accumbens cell surface Morphine decreases phosphorylation of Gria1 protein in the caudate-putamen, nucleus accumbens Morphine alters expression of Gria1 protein in prefrontal cortex membrane Morphine withdrawal increases phosphorylation of Gria1 protein in hippocampal formation postsynaptic density Morphine increases expression of Gria1 protein in the striatum Morphine increases expression of Gria1 protein in the central amygdaloid nucleus Morphine promotes the reaction [CREB1 protein modified form binds to GRIA1 promoter] Morphine results in increased expression of GRIA1 mRNA Morphine results in decreased expression of GRIA1 mRNA; Morphine results in decreased expression of GRIA1 protein Morphine results in decreased phosphorylation of GRIA1 protein
GRIK1 protein affects the reaction [Morphine results in increased expression of CALCA protein]; GRIK1 protein affects the reaction [Morphine results in increased expression of PDYN protein alternative form] GRIK1 protein affects the susceptibility to Morphine
[Morphine results in increased activity of OPRM1 protein] which results in increased phosphorylation of GRIN1 protein; MMP9 protein affects the reaction [Morphine results in increased phosphorylation of GRIN1 protein] morphine increases expression of Nr1 protein in cortical neurons morphine increases phosphorylation of Nr1 protein in frontal cortex and cortical neurons Morphine results in increased expression of GRIN1 protein Agmatine inhibits the reaction [Morphine results in increased expression of GRIN1 protein]; Morphine results in increased expression of [GRIN1 protein binds to GRIN2B protein binds to DLG4 protein]; resveratrol inhibits the reaction [Morphine results in increased expression of [GRIN1 protein binds to GRIN2B protein binds to DLG4 protein]]; resveratrol inhibits the reaction [Morphine results in increased expression of GRIN1 protein] Morphine results in decreased phosphorylation of GRIN1 protein Morphine affects the phosphorylation of GRIN1 protein
MMP9 protein affects the reaction [Morphine results in increased phosphorylation of GRIN2B protein] Morphine results in increased expression of GRIN2B protein Morphine results in increased expression of [GRIN1 protein binds to GRIN2B protein binds to DLG4 protein]; resveratrol inhibits the reaction [Morphine results in increased expression of [GRIN1 protein binds to GRIN2B protein binds to DLG4 protein]]; resveratrol inhibits the reaction [Morphine results in increased expression of GRIN2B protein]
Morphine results in increased expression of GSK3B protein modified form Naloxone inhibits the reaction [Morphine results in increased expression of GSK3B protein modified form]
HINT1 affects the reaction [Morphine promotes the reaction [OPRM1 protein binds to MAPK1 protein]]; HINT1 affects the reaction [Morphine promotes the reaction [OPRM1 protein binds to MAPK3 protein]]; HINT1 affects the reaction [Morphine promotes the reaction [OPRM1 protein binds to RAF1 protein]]; HINT1 gene mutant form inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCA protein]]; HINT1 gene mutant form inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCB protein]]; HINT1 gene mutant form inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCG protein]]; HINT1 gene mutant form inhibits the reaction [Morphine results in increased phosphorylation of OPRM1 protein] HINT1 gene mutant form results in increased susceptibility to Morphine
Chlorpheniramine inhibits the reaction [HRH1 results in decreased susceptibility to Morphine]; Cimetidine inhibits the reaction [HRH1 results in decreased susceptibility to Morphine]
[zolantidine binds to and results in decreased activity of HRH2 protein] which results in increased susceptibility to Morphine; Chlorpheniramine inhibits the reaction [HRH2 results in decreased susceptibility to Morphine]; Cimetidine inhibits the reaction [HRH2 results in decreased susceptibility to Morphine] HRH2 protein results in decreased susceptibility to Morphine; HRH2 results in decreased susceptibility to Morphine
Naloxone inhibits the reaction [Morphine results in increased expression of HSPA1A mRNA] Morphine results in increased expression of HSPA1A mRNA; Morphine results in increased expression of HSPA1A protein
Morphine results in increased expression of HSPA5 protein corilagin inhibits the reaction [Morphine results in increased expression of HSPA5 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of HSPA5 protein]]
4-(2'-methoxyphenyl)-1-(2'-(N-(2''-pyridinyl)-4-iodobenzamido)ethyl)piperazine inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Morphine]; [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Morphine Morphine decreases expression of Htr1a mRNA in the dorsal raphe nucleus
Morphine results in decreased expression of ICAM1 protein alternative form Naloxone inhibits the reaction [Morphine results in decreased expression of ICAM1 protein alternative form]; phosphoramidon inhibits the reaction [Morphine results in decreased expression of ICAM1 protein alternative form]
Morphine results in decreased expression of IDH3B protein Morphine deficiency affects the reaction [Morphine results in decreased expression of IDH3B protein]
Carrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein]; Dexamethasone inhibits the reaction [Carrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein]]; Dexamethasone inhibits the reaction [Morphine inhibits the reaction [Carrageenan results in decreased expression of IL1A protein]]; Morphine inhibits the reaction [Carrageenan results in decreased expression of IL1A protein]; Naloxone inhibits the reaction [Carrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein]]; Naloxone inhibits the reaction [Morphine inhibits the reaction [Carrageenan results in decreased expression of IL1A protein]]
Anti-Inflammatory Agents, Non-Steroidal inhibits the reaction [Morphine results in increased expression of IL1B mRNA]; Anti-Inflammatory Agents, Non-Steroidal inhibits the reaction [Morphine results in increased expression of IL1B protein]; resveratrol inhibits the reaction [Morphine results in increased expression of IL1B mRNA] corilagin inhibits the reaction [Morphine results in increased expression of IL1B protein]; dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [Morphine results in increased expression of IL1B protein]]; Minocycline inhibits the reaction [Morphine results in increased expression of IL1B protein]; Resveratrol inhibits the reaction [Morphine results in increased expression of IL1B protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of IL1B protein]]; Tunicamycin inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of IL1B protein]] Morphine results in increased expression of IL1B mRNA; Morphine results in increased expression of IL1B protein Morphine results in increased secretion of IL1B protein
Morphine results in decreased expression of IL2 Morphine results in decreased expression of IL2 mRNA OPRM1 gene mutant form inhibits the reaction [Morphine results in decreased expression of IL2]
[FAS protein binds to FASL protein] affects the reaction [Morphine results in increased expression of IL4 protein] Morphine results in increased expression of IL4 mRNA; Morphine results in increased expression of IL4 protein CTAP octapeptide inhibits the reaction [Morphine results in increased expression of IL4 mRNA]; SB 203580 inhibits the reaction [Morphine results in increased expression of IL4 mRNA]
Morphine results in increased secretion of IL6 protein corilagin inhibits the reaction [Morphine results in increased expression of IL6 protein]; dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [Morphine results in increased expression of IL6 protein]]; Minocycline inhibits the reaction [Morphine results in increased expression of IL6 protein]; Resveratrol inhibits the reaction [Morphine results in increased expression of IL6 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of IL6 protein]]; Tunicamycin inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of IL6 protein]] Morphine results in increased expression of IL6 mRNA; Morphine results in increased expression of IL6 protein Anti-Inflammatory Agents, Non-Steroidal inhibits the reaction [Morphine results in increased expression of IL6 mRNA]; Anti-Inflammatory Agents, Non-Steroidal inhibits the reaction [Morphine results in increased expression of IL6 protein]; resveratrol inhibits the reaction [Morphine results in increased expression of IL6 mRNA]
Acetylcysteine inhibits the reaction [Morphine results in increased phosphorylation of and results in increased activity of JUN protein]; Morphine results in increased phosphorylation of and results in increased activity of JUN protein; pyrazolanthrone inhibits the reaction [Morphine results in increased phosphorylation of and results in increased activity of JUN protein]
Morphine results in increased expression of KLF7 mRNA; Morphine results in increased expression of KLF7 protein Naloxone inhibits the reaction [Morphine results in increased expression of KLF7 mRNA]
Morphine results in decreased expression of KRT2 protein Morphine deficiency affects the reaction [Morphine results in decreased expression of KRT2 protein]
Morphine deficiency inhibits the reaction [Morphine deficiency promotes the reaction [Morphine results in increased expression of KRT33A protein]]; Morphine deficiency promotes the reaction [Morphine results in increased expression of KRT33A protein]
Morphine deficiency affects the reaction [Morphine deficiency affects the reaction [Morphine results in decreased expression of KRT8 protein]]; Morphine deficiency affects the reaction [Morphine results in decreased expression of KRT8 protein]
Morphine results in increased expression of MAPK1 protein modified form Morphine results in increased phosphorylation of MAPK1 protein [Morphine co-treated with Dehydroepiandrosterone Sulfate] results in decreased phosphorylation of MAPK1 protein; AM 251 inhibits the reaction [Morphine results in increased phosphorylation of MAPK1 protein]; HINT1 affects the reaction [Morphine promotes the reaction [OPRM1 protein binds to MAPK1 protein]]; MMP9 protein affects the reaction [Morphine results in increased phosphorylation of MAPK1 protein]; Morphine promotes the reaction [OPRM1 protein binds to MAPK1 protein]; suvorexant inhibits the reaction [Morphine results in increased phosphorylation of MAPK1 protein] Morphine deficiency results in increased phosphorylation of MAPK1 protein; Morphine results in increased phosphorylation of MAPK1 protein [CP 154526 binds to and results in decreased activity of CRHR1 protein] inhibits the reaction [Morphine deficiency results in increased phosphorylation of MAPK1 protein]; ARL6IP5 mutant form inhibits the reaction [Morphine results in increased phosphorylation of MAPK1 protein]; bilobalide inhibits the reaction [Oxaliplatin promotes the reaction [Morphine results in increased phosphorylation of MAPK1 protein]]; Oxaliplatin promotes the reaction [Morphine results in increased phosphorylation of MAPK1 protein] ARL6IP5 mutant form inhibits the reaction [Morphine results in increased phosphorylation of MAPK1 protein]; Morphine results in increased phosphorylation of and results in increased activity of MAPK1 protein; Naloxone promotes the reaction [Morphine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; OPRD1 mutant form inhibits the reaction [Morphine results in increased phosphorylation of MAPK1 protein]
ARL6IP5 mutant form inhibits the reaction [Morphine results in increased phosphorylation of MAPK3 protein]; Morphine results in increased phosphorylation of and results in increased activity of MAPK3 protein; Naloxone promotes the reaction [Morphine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; OPRD1 mutant form inhibits the reaction [Morphine results in increased phosphorylation of MAPK3 protein] AM 251 inhibits the reaction [Morphine results in increased phosphorylation of MAPK3 protein]; HINT1 affects the reaction [Morphine promotes the reaction [OPRM1 protein binds to MAPK3 protein]]; MMP9 protein affects the reaction [Morphine results in increased phosphorylation of MAPK3 protein]; Morphine promotes the reaction [OPRM1 protein binds to MAPK3 protein]; suvorexant inhibits the reaction [Morphine results in increased phosphorylation of MAPK3 protein] Morphine deficiency results in increased phosphorylation of MAPK3 protein; Morphine results in increased phosphorylation of MAPK3 protein [CP 154526 binds to and results in decreased activity of CRHR1 protein] inhibits the reaction [Morphine deficiency results in increased phosphorylation of MAPK3 protein]; ARL6IP5 mutant form inhibits the reaction [Morphine results in increased phosphorylation of MAPK3 protein]; bilobalide inhibits the reaction [Oxaliplatin promotes the reaction [Morphine results in increased phosphorylation of MAPK3 protein]]; Oxaliplatin promotes the reaction [Morphine results in increased phosphorylation of MAPK3 protein]
Naloxone inhibits the reaction [Morphine results in increased activity of MME protein]; phosphoramidon inhibits the reaction [Morphine results in increased activity of MME protein]
[7-nitroindazole results in decreased activity of NOS1 protein] inhibits the reaction [[Morphine co-treated with Naloxone] results in increased activity of MMP9 protein]; [Morphine co-treated with Naloxone] results in increased activity of MMP9 protein; MMP9 protein affects the reaction [Morphine results in increased phosphorylation of GRIN1 protein]; MMP9 protein affects the reaction [Morphine results in increased phosphorylation of GRIN2B protein]; MMP9 protein affects the reaction [Morphine results in increased phosphorylation of MAPK1 protein]; MMP9 protein affects the reaction [Morphine results in increased phosphorylation of MAPK3 protein] Morphine results in increased activity of MMP9 protein
Morphine results in increased phosphorylation of NFKBIA protein NFKBIA protein affects the susceptibility to Morphine Morphine results in increased expression of NFKBIA protein Morphine results in increased degradation of NFKBIA protein Morphine results in increased expression of NFKBIA mRNA; Morphine results in increased expression of NFKBIA protein Calcium affects the reaction [Morphine inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]; CTAP octapeptide inhibits the reaction [Morphine inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]; CTAP octapeptide inhibits the reaction [Morphine results in increased expression of NFKBIA mRNA]; Cycloheximide inhibits the reaction [Morphine results in increased expression of NFKBIA mRNA]; Morphine inhibits the reaction [Doxorubicin results in increased degradation of NFKBIA protein]; Morphine inhibits the reaction [TNF protein results in increased ubiquitination of and results in increased degradation of NFKBIA protein]; USP15 mutant form inhibits the reaction [Morphine inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]
corilagin inhibits the reaction [Morphine results in increased expression of NLRP3 protein]; Minocycline inhibits the reaction [Morphine results in increased expression of NLRP3 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of NLRP3 protein]]; Tunicamycin inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of NLRP3 protein]]
[7-nitroindazole results in decreased activity of NOS1 protein] inhibits the reaction [[Morphine co-treated with Naloxone] results in increased activity of MMP9 protein] Morphine results in decreased expression of NOS1 protein PENK protein alternative form inhibits the reaction [Morphine results in increased expression of NOS1 protein]
Morphine results in increased expression of NOS2 mRNA; Morphine results in increased expression of NOS2 protein corilagin inhibits the reaction [Morphine results in increased expression of NOS2 protein]; dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [Morphine results in increased expression of NOS2 protein]]; Minocycline inhibits the reaction [Morphine results in increased expression of NOS2 protein]; NOS2 protein promotes the reaction [[Morphine results in increased expression of PTGS2 protein] which results in increased abundance of 6-Ketoprostaglandin F1 alpha]; NOS2 protein promotes the reaction [[Morphine results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone]; Resveratrol inhibits the reaction [Morphine results in increased expression of NOS2 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of NOS2 protein]]; Tunicamycin inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of NOS2 protein]] NOS2 protein affects the susceptibility to Morphine
BDNF protein inhibits the reaction [NR4A2 protein affects the susceptibility to Morphine] Morphine results in decreased expression of NR4A2 mRNA Morphine inhibits the reaction [CREB1 protein modified form binds to NR4A2 promoter]; Morphine inhibits the reaction [NR4A2 protein binds to BDNF promoter]
ARL6IP5 mutant form inhibits the reaction [Morphine results in increased expression of OPRD1 protein]; Morphine promotes the reaction [ARL6IP5 protein binds to OPRD1 protein]; OPRD1 mutant form inhibits the reaction [Morphine results in increased phosphorylation of MAPK1 protein]; OPRD1 mutant form inhibits the reaction [Morphine results in increased phosphorylation of MAPK3 protein]; OPRD1 mutant form inhibits the reaction [Morphine results in increased phosphorylation of PPP1R1B protein] ARL6IP5 mutant form inhibits the reaction [Morphine results in increased expression of OPRD1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ARL6IP5 mutant form inhibits the reaction [Morphine results in increased expression of OPRD1 protein]]; Morphine promotes the reaction [ARL6IP5 protein binds to OPRD1 protein] Morphine binds to OPRD1 protein
Morphine affects the activity of OPRK1 protein Morphine results in increased activity of OPRK1 protein Morphine results in increased expression of OPRK1 mRNA Morphine binds to OPRK1 protein Morphine inhibits the reaction [Zymosan results in decreased expression of OPRK1 mRNA]
[[Naloxone binds to and results in decreased activity of OPRM1 protein] which co-treated with Morphine] results in increased expression of Cyclic AMP; [[Naltrexone binds to and results in decreased activity of OPRM1 protein] which co-treated with Morphine] results in increased expression of Cyclic AMP; [COMT gene SNP co-treated with OPRM1 gene SNP] affects the susceptibility to Morphine; [OPRM1 protein co-treated with Morphine] results in increased activity of ARRB2 protein; Morphine binds to and results in increased activity of OPRM1 protein; Morphine inhibits the reaction [Tretinoin results in increased expression of OPRM1 mRNA]; Naloxone inhibits the reaction [Morphine inhibits the reaction [Tretinoin results in increased expression of OPRM1 mRNA]]; OPRM1 protein affects the reaction [Morphine results in decreased secretion of FGF2 protein] morphine decreases expression of Oprm1 protein in cultured astrocytes Morphine results in increased phosphorylation of OPRM1 protein Morphine results in increased activity of OPRM1 protein Morphine results in decreased expression of OPRM1 mRNA OPRM1 affects the susceptibility to Morphine; OPRM1 protein affects the susceptibility to Morphine [Morphine results in increased activity of OPRM1 protein] which results in increased phosphorylation of GRIN1 protein; [phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide binds to and results in decreased activity of OPRM1 protein] which results in decreased susceptibility to Morphine; [Zymosan co-treated with Morphine] results in increased expression of OPRM1 mRNA; Dizocilpine Maleate inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCA protein]]; Dizocilpine Maleate inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCG protein]]; HINT1 affects the reaction [Morphine promotes the reaction [OPRM1 protein binds to MAPK1 protein]]; HINT1 affects the reaction [Morphine promotes the reaction [OPRM1 protein binds to MAPK3 protein]]; HINT1 affects the reaction [Morphine promotes the reaction [OPRM1 protein binds to RAF1 protein]]; HINT1 gene mutant form inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCA protein]]; HINT1 gene mutant form inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCB protein]]; HINT1 gene mutant form inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCG protein]]; HINT1 gene mutant form inhibits the reaction [Morphine results in increased phosphorylation of OPRM1 protein]; Morphine affects the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein]; Morphine binds to and affects the activity of OPRM1 protein; Morphine binds to and results in increased activity of OPRM1 protein; Morphine promotes the reaction [OPRM1 protein binds to MAPK1 protein]; Morphine promotes the reaction [OPRM1 protein binds to MAPK3 protein]; Morphine promotes the reaction [OPRM1 protein binds to PRKCA protein]; Morphine promotes the reaction [OPRM1 protein binds to PRKCB protein]; Morphine promotes the reaction [OPRM1 protein binds to PRKCG protein]; Morphine promotes the reaction [OPRM1 protein binds to RAF1 protein]; Naloxone inhibits the reaction [Morphine results in increased phosphorylation of OPRM1 protein]; OPRM1 gene mutant form inhibits the reaction [Morphine results in decreased expression of IFNG]; OPRM1 gene mutant form inhibits the reaction [Morphine results in decreased expression of IL2]; Tetradecanoylphorbol Acetate inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCG protein]]; valyl-prolyl-aspartyl-prolyl-arginine inhibits the reaction [Morphine results in increased activity of OPRM1 protein] Morphine results in increased expression of OPRM1 protein Morphine binds to OPRM1 protein OPRM1 affects the activity of Morphine [beta-funaltrexamine binds to and results in decreased activity of OPRM1 protein] inhibits the reaction [Morphine results in increased abundance of 3,4-Dihydroxyphenylacetic Acid]; [beta-funaltrexamine binds to and results in decreased activity of OPRM1 protein] inhibits the reaction [Morphine results in increased abundance of Homovanillic Acid]; [beta-funaltrexamine binds to and results in decreased activity of OPRM1 protein] which results in decreased susceptibility to Morphine; [Morphine binds to and results in increased activity of OPRM1 protein] which results in increased activity of ARRB2 protein; [naloxonazine binds to and results in decreased activity of OPRM1 protein] which affects the susceptibility to Morphine; [naloxonazine binds to and results in decreased activity of OPRM1 protein] which results in decreased susceptibility to Morphine; Morphine affects the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein]; Morphine binds to and affects the activity of OPRM1 protein; Morphine binds to and results in increased activity of OPRM1 protein OPRM1 exon SNP results in decreased susceptibility to Morphine Morphine affects the activity of OPRM1 protein
PDGFB protein inhibits the reaction [Morphine results in decreased expression of BCL2 protein]; PDGFB protein inhibits the reaction [Morphine results in increased activity of CASP3 protein]; PDGFB protein inhibits the reaction [Morphine results in increased expression of BAX protein] PDGFB protein results in decreased susceptibility to Morphine
Morphine results in increased expression of PDHB protein Morphine deficiency affects the reaction [Morphine results in increased expression of PDHB protein]
Morphine results in increased expression of PDYN protein alternative form Morphine deficiency results in decreased expression of PDYN mRNA Morphine results in decreased expression of PDYN mRNA [Zymosan co-treated with Morphine] results in increased expression of PDYN mRNA; GRIK1 protein affects the reaction [Morphine results in increased expression of PDYN protein alternative form]
Morphine inhibits the reaction [Formaldehyde results in increased expression of PENK mRNA]; PENK protein alternative form inhibits the reaction [Morphine results in increased expression of CALCA protein]; PENK protein alternative form inhibits the reaction [Morphine results in increased expression of NOS1 protein]; PENK protein alternative form inhibits the reaction [Morphine results in increased expression of PRKCG protein] Morphine deficiency results in decreased expression of PENK mRNA
[Fentanyl co-treated with Morphine] results in decreased expression of POMC protein alternative form Morphine deficiency results in increased secretion of POMC protein modified form [Clonidine co-treated with Naloxone co-treated with Morphine] results in increased secretion of POMC protein; [CP 154526 binds to and results in decreased activity of CRHR1 protein] inhibits the reaction [Morphine deficiency results in increased secretion of POMC protein modified form]; [Morphine co-treated with Naloxone] results in increased secretion of POMC protein; Capsaicin inhibits the reaction [[Clonidine co-treated with Naloxone co-treated with Morphine] results in increased secretion of POMC protein]; Capsaicin inhibits the reaction [[Morphine co-treated with Naloxone] results in increased secretion of POMC protein] [Zymosan co-treated with Morphine] results in increased expression of POMC mRNA Morphine results in increased expression of POMC mRNA
Morphine affects the expression of PPP1R1B protein modified form ARL6IP5 mutant form inhibits the reaction [Morphine results in increased phosphorylation of PPP1R1B protein] ARL6IP5 mutant form inhibits the reaction [Morphine results in increased phosphorylation of PPP1R1B protein]; OPRD1 mutant form inhibits the reaction [Morphine results in increased phosphorylation of PPP1R1B protein]
Dizocilpine Maleate inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCA protein]]; HINT1 gene mutant form inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCA protein]]; Morphine promotes the reaction [OPRM1 protein binds to PRKCA protein]
HINT1 gene mutant form inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCB protein]]; Morphine promotes the reaction [OPRM1 protein binds to PRKCB protein]
PENK protein alternative form inhibits the reaction [Morphine results in increased expression of PRKCG protein] Dizocilpine Maleate inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCG protein]]; HINT1 gene mutant form inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCG protein]]; Morphine promotes the reaction [OPRM1 protein binds to PRKCG protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCG protein]] Morphine results in increased expression of PRKCG protein modified form
Morphine results in decreased expression of PTGS1 mRNA Morphine results in increased expression of PTGS1 mRNA Minocycline inhibits the reaction [Morphine results in increased expression of PTGS1 mRNA]
Morphine results in increased expression of PTGS2 protein [nimesulide results in decreased activity of PTGS2 protein] which results in increased susceptibility to Morphine [Morphine results in increased expression of PTGS2 protein] which results in increased abundance of 6-Ketoprostaglandin F1 alpha; [Morphine results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone; corilagin inhibits the reaction [Morphine results in increased expression of PTGS2 protein]; Minocycline inhibits the reaction [Morphine results in increased expression of PTGS2 protein]; NOS2 protein promotes the reaction [[Morphine results in increased expression of PTGS2 protein] which results in increased abundance of 6-Ketoprostaglandin F1 alpha]; NOS2 protein promotes the reaction [[Morphine results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone]; S-methylisothiopseudouronium inhibits the reaction [[Morphine results in increased expression of PTGS2 protein] which results in increased abundance of 6-Ketoprostaglandin F1 alpha]; S-methylisothiopseudouronium inhibits the reaction [[Morphine results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of PTGS2 protein]]; Tunicamycin inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of PTGS2 protein]]
Morphine results in decreased expression of PYCARD mRNA Morphine results in increased expression of PYCARD protein corilagin inhibits the reaction [Morphine results in increased expression of PYCARD protein]; Minocycline inhibits the reaction [Morphine results in increased expression of PYCARD protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of PYCARD protein]]; Tunicamycin inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of PYCARD protein]]
RAF1 protein affects the susceptibility to Morphine HINT1 affects the reaction [Morphine promotes the reaction [OPRM1 protein binds to RAF1 protein]]; Morphine promotes the reaction [OPRM1 protein binds to RAF1 protein]
Morphine inhibits the reaction [Doxorubicin affects the localization of RELA protein] Colforsin inhibits the reaction [Morphine results in increased phosphorylation of RELA protein]
Morphine results in increased expression of RGS6 mRNA naloxone cotreated with morphine decreases expression of Rgs6 mRNA in central gray substance of midbrain and striatum
Morphine results in decreased expression of SELL protein alternative form Naloxone inhibits the reaction [Morphine results in decreased expression of SELL protein alternative form]; phosphoramidon inhibits the reaction [Morphine results in decreased expression of SELL protein alternative form]
Morphine deficiency inhibits the reaction [Morphine deficiency inhibits the reaction [Morphine results in decreased expression of SEPTIN7 protein]]; Morphine deficiency inhibits the reaction [Morphine results in decreased expression of SEPTIN7 protein]
[NNC 711 results in decreased activity of SLC6A1 protein] which affects the susceptibility to Morphine SLC6A1 protein affects the susceptibility to Morphine
Morphine affects the reaction [SMPD1 protein affects the abundance of Ceramides]; Naloxone inhibits the reaction [Morphine results in increased expression of SMPD1 protein]
Morphine results in increased expression of SMPX protein Morphine deficiency affects the reaction [Morphine results in increased expression of SMPX protein]
Morphine deficiency results in increased expression of TAC1 mRNA; Morphine results in increased expression of TAC1 mRNA Morphine results in increased expression of TAC1 protein Morphine promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; Naloxone inhibits the reaction [Morphine results in increased expression of TAC1 protein]
[SR 140333 binds to and results in decreased activity of TACR1 protein] which results in increased susceptibility to Morphine; substance P-saporin inhibits the reaction [Morphine results in increased expression of TACR1 protein] Morphine results in decreased expression of TACR1 protein
Morphine results in increased expression of and results in increased localization of TGFB1 protein; TGFB1 protein affects the reaction [Morphine results in increased expression of and results in increased localization of TGFB1 protein]; TGFB1 protein affects the reaction [Morphine results in increased expression of BAX protein]
Morphine results in increased expression of TH protein [CP 154526 binds to and results in decreased activity of CRHR1 protein] inhibits the reaction [Morphine deficiency results in increased phosphorylation of TH protein]; [Morphine co-treated with Naloxone] results in increased phosphorylation of TH protein; Agmatine inhibits the reaction [Morphine results in increased expression of TH protein]; Morphine promotes the reaction [CREB1 protein modified form binds to TH promoter] Morphine results in decreased expression of TH protein [Morphine co-treated with Naloxone] results in increased phosphorylation of TH protein; CRHR1 gene mutant form inhibits the reaction [[Morphine co-treated with Naloxone] results in increased phosphorylation of TH protein]
Morphine results in increased expression of TLR2 mRNA; Morphine results in increased expression of TLR2 protein corilagin inhibits the reaction [Morphine results in increased expression of TLR2 mRNA]; corilagin inhibits the reaction [Morphine results in increased expression of TLR2 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased cleavage of CASP3 protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of AIF1 protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of ATF4 protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of DDIT3 protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of HSPA5 protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of IL1B protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of IL6 protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of NLRP3 protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of NOS2 protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of PTGS2 protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of PYCARD protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of TNF protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased phosphorylation of EIF2AK3 protein]]
Morphine binds to TLR4 protein Morphine results in increased expression of TLR4 protein dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [Morphine results in increased expression of TLR4 protein]]; Resveratrol inhibits the reaction [Morphine results in increased expression of TLR4 protein] Morphine affects the susceptibility to TLR4 protein Naloxone affects the reaction [Morphine binds to TLR4 protein]
Anti-Inflammatory Agents, Non-Steroidal inhibits the reaction [Morphine results in increased expression of TNF mRNA]; Anti-Inflammatory Agents, Non-Steroidal inhibits the reaction [Morphine results in increased expression of TNF protein]; Morphine inhibits the reaction [TNF protein results in increased expression of CNR1 mRNA]; Resveratrol inhibits the reaction [Morphine results in increased expression of TNF mRNA] corilagin inhibits the reaction [Morphine results in increased expression of TNF protein]; dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [Morphine results in increased expression of TNF protein]]; Minocycline inhibits the reaction [Morphine results in increased expression of TNF protein]; Resveratrol inhibits the reaction [Morphine results in increased expression of TNF protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of TNF protein]]; Tunicamycin inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of TNF protein]] Calcium affects the reaction [Morphine inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]; CTAP octapeptide inhibits the reaction [Morphine inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]; CTAP octapeptide inhibits the reaction [Morphine inhibits the reaction [TNF protein results in increased expression of CNR1 mRNA]]; CTAP octapeptide inhibits the reaction [Morphine inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]]; Cycloheximide inhibits the reaction [Morphine inhibits the reaction [TNF protein results in increased expression of CNR1 mRNA]]; Cycloheximide inhibits the reaction [Morphine inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]]; Morphine inhibits the reaction [TNF protein results in increased expression of CNR1 mRNA]; Morphine inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; Morphine inhibits the reaction [TNF protein results in increased ubiquitination of and results in increased degradation of NFKBIA protein]; USP15 mutant form inhibits the reaction [Morphine inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]] Morphine results in increased expression of TNF mRNA; Morphine results in increased expression of TNF protein Morphine results in increased secretion of TNF protein
[Morphine results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of BAX protein; [Morphine results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of CDKN1A protein; [Morphine results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of FAS protein; Morphine inhibits the reaction [Dactinomycin results in increased expression of TP53 protein modified form]; Morphine results in increased phosphorylation of and results in increased activity of TP53 protein; Morphine results in increased phosphorylation of and results in increased stability of TP53 protein; Naloxone inhibits the reaction [Morphine inhibits the reaction [Dactinomycin results in increased expression of TP53 protein modified form]]; Naloxone inhibits the reaction [Morphine results in increased expression of TP53]; Naloxone inhibits the reaction [Morphine results in increased phosphorylation of TP53 protein] Morphine results in increased expression of TP53 mRNA
[N-(7-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)-3-(2-(piperidin-1-yl)-6-(trifluoromethyl)pyridin-3-yl)acrylamide binds to and results in decreased activity of TRPV1 protein] which results in decreased susceptibility to Morphine Morphine affects the activity of TRPV1 protein Morphine results in increased expression of TRPV1; Morphine results in increased expression of TRPV1 protein TRPV1 protein affects the susceptibility to Morphine
Morphine results in decreased expression of TTR protein Morphine deficiency affects the reaction [Morphine results in decreased expression of TTR protein]
UGT2B7 affects the metabolism of Morphine; UGT2B7 protein affects the metabolism of Morphine UGT2B7 protein results in increased glucuronidation of Morphine
Calcium affects the reaction [Morphine results in increased expression of USP15 mRNA]; CTAP octapeptide inhibits the reaction [Morphine results in increased expression of USP15 mRNA]; USP15 mutant form inhibits the reaction [Morphine inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]] Morphine results in increased expression of USP15 mRNA; Morphine results in increased expression of USP15 protein
[Ciprofloxacin results in decreased activity of CYP1A2 protein] which results in increased abundance of norclozapine; Fluvoxamine inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of norclozapine] CYP1A2 protein results in increased metabolism of norclozapine
CYP3A4 protein results in increased chemical synthesis of norclozapine Ketoconazole inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of norclozapine]
Naloxone promotes the reaction [AGT protein results in increased expression of CRH protein]; Naloxone promotes the reaction [AGT protein results in increased expression of FOS protein]; Naloxone promotes the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Naloxone promotes the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]
Naloxone results in decreased secretion of AVP protein Naloxone decreases expression of Avp mRNA in the hypothalamus Naloxone increases expression of Avp mRNA in paraventricular nucleus of hypothalamus
Naloxone inhibits the reaction [Morphine inhibits the reaction [Dactinomycin results in decreased expression of BCL2 protein]] Naloxone results in increased expression of BCL2 protein
Naloxone affects the activity of CALCA protein Naloxone inhibits the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]]; Naloxone inhibits the reaction [Fentanyl inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]]
Naloxone inhibits the reaction [Morphine results in increased activity of CASP3 protein]; Naloxone inhibits the reaction [Morphine results in increased expression of CASP3 protein alternative form]
[CP 154526 binds to and results in decreased activity of CRHR1 protein] inhibits the reaction [Naloxone affects the abundance of Norepinephrine]; [CP 154526 binds to and results in decreased activity of CRHR1 protein] inhibits the reaction [Naloxone results in increased phosphorylation of TH protein]; [CP 154526 binds to and results in decreased activity of CRHR1 protein] inhibits the reaction [Naloxone results in increased secretion of POMC protein modified form]; [CP 154526 binds to and results in decreased activity of CRHR1 protein] which results in decreased susceptibility to Naloxone CRHR1 gene mutant form results in increased susceptibility to Naloxone CRHR1 gene mutant form inhibits the reaction [[Morphine co-treated with Naloxone] results in increased phosphorylation of TH protein]
[3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-1H-pyrrolo(2,3-b)pyridine binds to and results in decreased activity of DRD4 protein] inhibits the reaction [Naloxone results in increased abundance of Cyclic AMP]
[Morphine co-treated with Dizocilpine Maleate] inhibits the reaction [Naloxone results in increased expression of FOS protein] 1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea inhibits the reaction [[Morphine co-treated with Naloxone] results in increased expression of FOS protein]; [Morphine co-treated with Naloxone] results in increased expression of FOS protein; [Naloxone co-treated with Morphine] results in increased expression of FOS protein; Naloxone promotes the reaction [AGT protein results in increased expression of FOS protein]; Pentobarbital promotes the reaction [Naloxone results in increased expression of FOS protein]; SL 327 inhibits the reaction [Naloxone results in increased expression of FOS protein]
Naloxone inhibits the reaction [Carrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein]]; Naloxone inhibits the reaction [Morphine inhibits the reaction [Carrageenan results in decreased expression of IL1A protein]]
Naloxone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] naloxone inhibits the reaction [methamphetamine increases expression of IL6 mRNA in ventral tegmental area]
Naloxone results in increased expression of LHB protein Naloxone affects the expression of LHB protein Naloxone affects the expression of and affects the secretion of LHB protein
Naloxone promotes the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Naloxone results in increased phosphorylation of and results in increased activity of MAPK1 protein Naloxone results in increased phosphorylation of MAPK1 protein Naloxone promotes the reaction [Morphine results in increased phosphorylation of and results in increased activity of MAPK1 protein]
Naloxone promotes the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; Naloxone results in increased phosphorylation of and results in increased activity of MAPK3 protein Naloxone results in increased phosphorylation of MAPK3 protein Naloxone promotes the reaction [Morphine results in increased phosphorylation of and results in increased activity of MAPK3 protein]
[7-nitroindazole results in decreased activity of NOS1 protein] inhibits the reaction [[Morphine co-treated with Naloxone] results in increased activity of MMP9 protein]; [Morphine co-treated with Naloxone] results in increased activity of MMP9 protein
[7-nitroindazole results in decreased activity of NOS1 protein] inhibits the reaction [[Morphine co-treated with Naloxone] results in increased activity of MMP9 protein]
[[Naloxone binds to and results in decreased activity of OPRM1 protein] which co-treated with Morphine] results in increased expression of Cyclic AMP; Naloxone inhibits the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to and results in increased activity of OPRM1 protein]; Naloxone inhibits the reaction [Morphine inhibits the reaction [Tretinoin results in increased expression of OPRM1 mRNA]] [naloxone cotreatment with morphine] inhibits the reaction [morphine decreases expression of Oprm1 protein in cultured astrocytes] Naloxone inhibits the reaction [Morphine results in increased phosphorylation of OPRM1 protein] Naloxone binds to OPRM1 protein [Naloxone binds to and results in decreased activity of OPRM1 protein] which results in decreased susceptibility to Clonidine; [Naloxone binds to and results in decreased activity of OPRM1 protein] which results in decreased susceptibility to Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; [Naloxone binds to and results in decreased activity of OPRM1 protein] which results in decreased susceptibility to N(6)-cyclopentyladenosine; Cannabidiol promotes the reaction [Naloxone inhibits the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to and results in increased activity of OPRM1 protein]]; Dronabinol promotes the reaction [Naloxone inhibits the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to and results in increased activity of OPRM1 protein]]; Naloxone binds to and results in decreased activity of OPRM1 protein; Naloxone inhibits the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to and results in increased activity of OPRM1 protein]
[Clonidine results in increased expression of POMC protein] which results in increased susceptibility to Naloxone; Naloxone binds to and results in increased activity of POMC protein alternative form Naloxone results in increased secretion of POMC protein modified form [Clonidine co-treated with Naloxone co-treated with Morphine] results in increased secretion of POMC protein; [CP 154526 binds to and results in decreased activity of CRHR1 protein] inhibits the reaction [Naloxone results in increased secretion of POMC protein modified form]; [Morphine co-treated with Naloxone] results in increased secretion of POMC protein; Capsaicin inhibits the reaction [[Clonidine co-treated with Naloxone co-treated with Morphine] results in increased secretion of POMC protein]; Capsaicin inhibits the reaction [[Morphine co-treated with Naloxone] results in increased secretion of POMC protein] Naloxone results in increased expression of POMC protein alternative form
[CP 154526 binds to and results in decreased activity of CRHR1 protein] inhibits the reaction [Naloxone results in increased phosphorylation of TH protein]; [Morphine co-treated with Naloxone] results in increased phosphorylation of TH protein [Morphine co-treated with Naloxone] results in increased phosphorylation of TH protein; CRHR1 gene mutant form inhibits the reaction [[Morphine co-treated with Naloxone] results in increased phosphorylation of TH protein]
Naloxone inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] Naloxone results in decreased expression of TNF protein
Naloxone inhibits the reaction [Morphine inhibits the reaction [Dactinomycin results in increased expression of TP53 protein modified form]]; Naloxone inhibits the reaction [Morphine results in increased expression of TP53]; Naloxone inhibits the reaction [Morphine results in increased phosphorylation of TP53 protein] Naloxone results in decreased expression of TP53 mRNA
Naltrexone affects the reaction [Dynorphins results in decreased secretion of CRH protein]; Naltrexone inhibits the reaction [beta-Endorphin results in decreased secretion of CRH protein] Naltrexone results in increased secretion of CRH protein
Naltrexone inhibits the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; Naltrexone inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]
[[Naltrexone binds to and results in decreased activity of OPRM1 protein] which co-treated with Morphine] results in increased expression of Cyclic AMP [Cannabidiol co-treated with Naltrexone] results in decreased expression of OPRM1 mRNA Naltrexone binds to OPRM1 protein OPRM1 affects the susceptibility to Naltrexone
Naltrexone inhibits the reaction [Enkephalin, Leucine-2-Alanine inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]] SLC6A3 gene polymorphism affects the susceptibility to Naltrexone
Oxycodone affects the expression of CYP2B2 mRNA Oxycodone results in increased expression of CYP2B2 mRNA; Oxycodone results in increased expression of CYP2B2 protein
CYP2D6 gene polymorphism affects the susceptibility to Oxycodone [Quinidine results in decreased activity of CYP2D6 protein] which affects the susceptibility to Oxycodone
Oxycodone inhibits the reaction [CYP3A2 protein results in increased hydroxylation of Testosterone] CYP3A4 protein alternative form affects the metabolism of Oxycodone telithromycin inhibits the reaction [CYP3A4 protein results in decreased methylation of Oxycodone] Oxycodone results in decreased expression of CYP3A2 mRNA; Oxycodone results in decreased expression of CYP3A2 protein
Oxycodone inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; Oxycodone inhibits the reaction [PDCD4 protein inhibits the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]]; Oxycodone promotes the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]
Oxycodone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Oxycodone inhibits the reaction [PDCD4 protein inhibits the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]]; Oxycodone promotes the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]
Oxycodone inhibits the reaction [Lipopolysaccharides results in decreased expression of MIR181C protein]; Oxycodone inhibits the reaction [PDCD4 protein inhibits the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein]]]; Oxycodone inhibits the reaction [PDCD4 protein inhibits the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]]; Oxycodone inhibits the reaction [PDCD4 protein inhibits the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]]; Oxycodone inhibits the reaction [PDCD4 protein inhibits the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]]; Oxycodone inhibits the reaction [PDCD4 protein inhibits the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]]; Oxycodone promotes the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein]]; Oxycodone promotes the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]; Oxycodone promotes the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; Oxycodone promotes the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; Oxycodone promotes the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of PDCD4 protein]]; Oxycodone promotes the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]
Oxycodone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Oxycodone inhibits the reaction [PDCD4 protein inhibits the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]]; Oxycodone promotes the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]
Oxycodone inhibits the reaction [Lipopolysaccharides results in increased expression of PDCD4 protein]; Oxycodone inhibits the reaction [PDCD4 protein inhibits the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein]]]; Oxycodone inhibits the reaction [PDCD4 protein inhibits the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]]; Oxycodone inhibits the reaction [PDCD4 protein inhibits the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]]; Oxycodone inhibits the reaction [PDCD4 protein inhibits the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]]; Oxycodone inhibits the reaction [PDCD4 protein inhibits the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]]; Oxycodone promotes the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of PDCD4 protein]]
Oxycodone inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Oxycodone inhibits the reaction [PDCD4 protein inhibits the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]]; Oxycodone promotes the reaction [MIR181C inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]
[Antagomirs results in decreased expression of MIR205 mRNA] promotes the reaction [Remifentanil inhibits the reaction [[Oxygen co-treated with Dithionite] results in increased expression of CASP3 protein modified form]]; [Antagomirs results in decreased expression of MIR205 mRNA] promotes the reaction [Remifentanil inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of CASP3 protein modified form]]; MIR205 mRNA inhibits the reaction [Remifentanil inhibits the reaction [[Oxygen co-treated with Dithionite] results in increased expression of CASP3 protein modified form]]; Remifentanil inhibits the reaction [[Oxygen co-treated with Dithionite] results in increased expression of CASP3 protein modified form]; Remifentanil inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of CASP3 protein modified form]
[Antagomirs results in decreased expression of MIR205 mRNA] promotes the reaction [Remifentanil inhibits the reaction [[Oxygen co-treated with Dithionite] results in increased expression of CASP3 protein modified form]]; [Antagomirs results in decreased expression of MIR205 mRNA] promotes the reaction [Remifentanil inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of PINK1 protein]]; [Antagomirs results in decreased expression of MIR205 mRNA] promotes the reaction [Remifentanil inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of CASP3 protein modified form]]; [Antagomirs results in decreased expression of MIR205 mRNA] promotes the reaction [Remifentanil inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of MIR205 mRNA]]; [Antagomirs results in decreased expression of MIR205 mRNA] which results in increased susceptibility to Remifentanil; MIR205 mRNA inhibits the reaction [Remifentanil inhibits the reaction [[Oxygen co-treated with Dithionite] results in increased expression of CASP3 protein modified form]]; Remifentanil inhibits the reaction [[Oxygen co-treated with Dithionite] results in increased expression of MIR205 mRNA]; Remifentanil inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of MIR205 mRNA]
[Antagomirs results in decreased expression of MIR205 mRNA] promotes the reaction [Remifentanil inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of PINK1 protein]]; Remifentanil inhibits the reaction [[Oxygen co-treated with Dithionite] results in decreased expression of PINK1 protein]; Remifentanil inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of PINK1 protein]
Tramadol affects the activity of CASP3 protein Tramadol results in increased expression of CASP3 protein Vitamin E inhibits the reaction [Tramadol results in increased expression of CASP3 protein] Tramadol results in decreased activity of CASP3 protein
Tramadol results in decreased expression of CAT mRNA; Tramadol results in decreased expression of CAT protein Tramadol deficiency inhibits the reaction [Tramadol results in increased expression of CAT mRNA]
Tramadol results in decreased expression of CKB mRNA Ethanol promotes the reaction [Tramadol results in increased expression of [CKM protein binds to CKB protein]]; Tramadol promotes the reaction [Ethanol results in increased expression of [CKM protein binds to CKB protein]]; Tramadol results in increased expression of [CKM protein binds to CKB protein]
Ethanol promotes the reaction [Tramadol results in increased expression of [CKM protein binds to CKB protein]]; Tramadol promotes the reaction [Ethanol results in increased expression of [CKM protein binds to CKB protein]]; Tramadol results in increased expression of [CKM protein binds to CKB protein]
CYP2D6 gene mutant form results in increased susceptibility to Tramadol CYP2D6 gene mutant form affects the metabolism of Tramadol; CYP2D6 gene polymorphism affects the metabolism of Tramadol CYP2D6 gene polymorphism results in decreased susceptibility to Tramadol CYP2D6 affects the susceptibility to Tramadol; CYP2D6 gene polymorphism affects the susceptibility to Tramadol; CYP2D6 protein affects the susceptibility to Tramadol [CYP2D6 protein results in increased metabolism of and results in increased activity of Tramadol] which results in increased chemical synthesis of O-demethyltramadol; CYP2D6 gene polymorphism affects the metabolism of and affects the susceptibility to Tramadol; CYP2D6 protein results in increased metabolism of and results in increased activity of Tramadol CYP2D6 protein results in decreased methylation of Tramadol CYP2D6 gene mutant form results in increased metabolism of Tramadol; CYP2D6 protein results in increased metabolism of Tramadol CYP2D6 protein affects the methylation of Tramadol
Tramadol binds to OPRD1 protein [Tramadol binds to OPRD1 protein] which results in decreased uptake of Norepinephrine; [Tramadol binds to OPRD1 protein] which results in decreased uptake of Serotonin
[Tramadol binds to OPRK1 protein] which results in decreased uptake of Norepinephrine; [Tramadol binds to OPRK1 protein] which results in decreased uptake of Serotonin
[Tramadol binds to OPRM1 protein] which results in decreased uptake of Norepinephrine; [Tramadol binds to OPRM1 protein] which results in decreased uptake of Serotonin
Naloxone inhibits the reaction [Tramadol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]]; Tramadol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Tramadol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]
Tramadol results in decreased expression of SOD1 mRNA; Tramadol results in decreased expression of SOD1 protein Tramadol deficiency inhibits the reaction [Tramadol results in increased expression of SOD1 mRNA]
Tramadol deficiency inhibits the reaction [Tramadol results in increased expression of SOD2 mRNA] Tramadol results in decreased expression of SOD2 mRNA
Ethanol promotes the reaction [Tramadol results in increased expression of SPP1 protein]; Tramadol promotes the reaction [Ethanol results in increased expression of SPP1 protein]
[Acetaminophen co-treated with Tramadol] inhibits the reaction [Freund's Adjuvant results in increased expression of TNF protein]; Tramadol promotes the reaction [Ethanol results in increased expression of TNF protein]; Vitamin E inhibits the reaction [Tramadol results in increased expression of TNF protein]
Tramadol results in increased expression of TNNI3 protein Ethanol promotes the reaction [Tramadol results in increased expression of TNNI3 protein]; Tramadol promotes the reaction [Ethanol results in increased expression of TNNI3 protein]
3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer results in increased phosphorylation of GRPR protein bisindolylmaleimide inhibits the reaction [3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer results in increased phosphorylation of GRPR protein]
3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer binds to and results in increased activity of OPRK1 protein; [3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer binds to and results in increased activity of OPRK1 protein] which results in increased phosphorylation of STAT3 protein 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer results in increased activity of OPRK1 protein OPRK1 protein affects the susceptibility to 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer binds to and results in increased activity of OPRK1 protein; 7-hydroxymitragynine inhibits the reaction [3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer binds to and results in increased activity of OPRK1 protein]; mitragynine inhibits the reaction [3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer binds to and results in increased activity of OPRK1 protein]
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer affects the localization of PRKCD protein]
[3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer binds to and results in increased activity of OPRK1 protein] which results in increased phosphorylation of STAT3 protein
U 69593 results in increased phosphorylation of MAPK1 protein norbinaltorphimine inhibits the reaction [U 69593 results in increased phosphorylation of MAPK1 protein]
U 69593 results in increased phosphorylation of MAPK3 protein norbinaltorphimine inhibits the reaction [U 69593 results in increased phosphorylation of MAPK3 protein]
U 69593 binds to OPRK1 protein Buprenorphine inhibits the reaction [U 69593 binds to OPRK1 protein]; U 69593 binds to and results in increased activity of OPRK1 protein [U 69593 binds to and results in increased activity of OPRK1 protein] inhibits the reaction [Cocaine affects the abundance of Dopamine]; U 69593 binds to and results in increased activity of OPRK1 protein
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