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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:calcium oxalate
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Accession:CHEBI:60579 term browser browse the term
Definition:The calcium salt of oxalic acid, which in excess in the urine may lead to formation of oxalate calculi (kidney stones).
Synonyms:related_synonym: Formula=C2CaO4;   InChI=1S/C2H2O4.Ca/c3-1(4)2(5)6;/h(H,3,4)(H,5,6);/q;+2/p-2;   InChIKey=QXDMQSPYEZFLGF-UHFFFAOYSA-L;   SMILES=[Ca++].[O-]C(=O)C([O-])=O
 xref: CAS:563-72-4;   KEGG:C17478
 xref_mesh: MESH:D002129
 xref: Reaxys:3915709

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calcium oxalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 multiple interactions
increases activity
EXP Diosgenin inhibits the reaction [Calcium Oxalate results in increased activity of CASP3 protein] CTD PMID:25446497 NCBI chr16:45,920,074...45,940,507
Ensembl chr16:45,920,071...45,940,505
JBrowse link
G CASP9 caspase 9 increases activity
multiple interactions
EXP Calcium Oxalate results in increased activity of CASP9 protein
Diosgenin inhibits the reaction [Calcium Oxalate results in increased activity of CASP9 protein]
CTD PMID:25446497 NCBI chr 2:82,033,759...82,076,710
Ensembl chr 2:82,031,563...82,090,484
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 221
    chemical entity 221
      molecular entity 221
        polyatomic entity 213
          heteroatomic molecular entity 175
            salt 15
              organic salt 4
                organic calcium salt 2
                  calcium oxalate 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 221
    subatomic particle 221
      composite particle 221
        hadron 221
          baryon 221
            nucleon 221
              atomic nucleus 221
                atom 221
                  main group element atom 214
                    p-block element atom 214
                      carbon group element atom 203
                        carbon atom 202
                          organic molecular entity 202
                            organic ion 13
                              organic anion 6
                                carboxylic acid anion 5
                                  dicarboxylic acid anion 2
                                    oxalate 2
                                      oxalate(2-) 2
                                        calcium oxalate 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.