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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(R)-etodolac
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Accession:CHEBI:60370 term browser browse the term
Definition:The R-enantiomer of etodolac. It is inactive, in contrast to the enantiomer, (S)-etodolac, which is a preferential inhibitor of cyclo-oxygenase 2 and a non-steroidal anti-inflammatory. The racemate is commonly used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain.
Synonyms:exact_synonym: [(1R)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl]acetic acid
 related_synonym: (-)-[1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl]acetic acid;   (-)-etodolac;   Formula=C17H21NO3;   InChI=1S/C17H21NO3/c1-3-11-6-5-7-12-13-8-9-21-17(4-2,10-14(19)20)16(13)18-15(11)12/h5-7,18H,3-4,8-10H2,1-2H3,(H,19,20)/t17-/m1/s1;   InChIKey=NNYBQONXHNTVIJ-QGZVFWFLSA-N;   SMILES=CCc1cccc2c3CCO[C@](CC)(CC(O)=O)c3[nH]c12
 xref: CAS:848873-99-4;   LINCS:LSM-6021
 cyclic_relationship: is_enantiomer_of CHEBI:60371


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Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      application 19630
        anti-inflammatory agent 16579
          anti-inflammatory drug 14922
            non-steroidal anti-inflammatory drug 14259
              etodolac 30
                (R)-etodolac 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      carbon group element atom 19708
                        carbon atom 19734
                          organic molecular entity 19705
                            heteroorganic entity 19459
                              organochalcogen compound 19222
                                organooxygen compound 19137
                                  carbon oxoacid 18597
                                    carboxylic acid 18594
                                      monocarboxylic acid 17952
                                        etodolac 30
                                          (R)-etodolac 0
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