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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N(6),N(6)-dimethyladenine
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Accession:CHEBI:60281 term browser browse the term
Definition:A tertiary amine that is adenine substituted at N-6 by geminal methyl groups.
Synonyms:exact_synonym: N,N-dimethyl-9H-purin-6-amine
 related_synonym: 6-(Dimethylamino)purine;   6-Dimethyladenine;   6-Dimethylaminopurine;   Formula=C7H9N5;   InChI=1S/C7H9N5/c1-12(2)7-5-6(9-3-8-5)10-4-11-7/h3-4H,1-2H3,(H,8,9,10,11);   InChIKey=BVIAOQMSVZHOJM-UHFFFAOYSA-N;   N(6)-dimethyladenine;   N,N-Dimethyl-6-aminopurine;   N,N-Dimethyladenine;   N,N-dimethyl-1H-purin-6-amine;   SMILES=CN(C)c1ncnc2[nH]cnc12
 xref: Beilstein:611068;   CAS:938-55-6
 xref_mesh: MESH:C001020
 xref: PMID:12112604;   PMID:19569655;   PMID:238583;   PMID:25730023;   PMID:323854


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N(6),N(6)-dimethyladenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin multiple interactions EXP N(6),N(6)-dimethyladenine inhibits the reaction [Cadmium Chloride results in increased expression of A2M protein] CTD PMID:15618353 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Cdh1 cadherin 1 multiple interactions EXP N(6),N(6)-dimethyladenine promotes the reaction [Cadmium Chloride results in decreased expression of CDH1 protein] CTD PMID:15618353 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh2 cadherin 2 multiple interactions EXP N(6),N(6)-dimethyladenine promotes the reaction [Cadmium Chloride results in decreased expression of CDH2 protein] CTD PMID:15618353 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions EXP N(6),N(6)-dimethyladenine promotes the reaction [Cadmium Chloride results in decreased expression of CTNNB1 protein] CTD PMID:15618353 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Lig1 DNA ligase 1 multiple interactions ISO N(6),N(6)-dimethyladenine inhibits the reaction [2-chloroethyl ethyl sulfide results in increased phosphorylation of LIG1 protein] CTD PMID:16700562 NCBI chr 1:75,356,212...75,394,757
Ensembl chr 1:75,356,220...75,394,758
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP N(6),N(6)-dimethyladenine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:15618353 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions EXP N(6),N(6)-dimethyladenine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein] CTD PMID:15618353 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Ocln occludin multiple interactions EXP N(6),N(6)-dimethyladenine promotes the reaction [Cadmium Chloride results in decreased expression of OCLN protein] CTD PMID:15618353 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions EXP N(6),N(6)-dimethyladenine promotes the reaction [Cadmium Chloride results in decreased expression of TJP1 protein] CTD PMID:15618353 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19883
    role 19833
      application 19505
        refrigerant 17516
          ammonia 17042
            organic amino compound 17041
              amine 7792
                tertiary amine 610
                  N(6),N(6)-dimethyladenine 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19883
    subatomic particle 19881
      composite particle 19881
        hadron 19881
          baryon 19881
            nucleon 19881
              atomic nucleus 19881
                atom 19881
                  main group element atom 19771
                    p-block element atom 19771
                      carbon group element atom 19679
                        carbon atom 19668
                          organic molecular entity 19668
                            organic molecule 19596
                              organic cyclic compound 19407
                                organic heterocyclic compound 18517
                                  organic heteropolycyclic compound 17907
                                    organic heterobicyclic compound 16828
                                      imidazopyrimidine 5586
                                        purines 5584
                                          aminopurine 4413
                                            6-aminopurines 787
                                              adenine 781
                                                N(6),N(6)-dimethyladenine 9
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