Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:lead ion
go back to main search page
Accession:CHEBI:60249 term browser browse the term
Definition:A lead atom having a net electric charge.


show annotations for term's descendants           Sort by:
 
lead diacetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 increases expression EXP lead acetate results in increased expression of AKT1 mRNA CTD PMID:29273543
G AMH anti-Mullerian hormone decreases expression
multiple interactions
EXP lead acetate results in decreased expression of AMH mRNA
lead acetate results in decreased expression of and results in decreased secretion of AMH protein
CTD PMID:29273543 NCBI chr 2:76,415,564...76,418,315
Ensembl chr 2:76,405,253...76,418,312
JBrowse link
G FSHB follicle stimulating hormone subunit beta multiple interactions EXP lead acetate inhibits the reaction [FSHB protein results in increased chemical synthesis of Estradiol] CTD PMID:29273543 NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274
JBrowse link
G FSHR follicle stimulating hormone receptor decreases expression EXP lead acetate results in decreased expression of FSHR mRNA CTD PMID:29273543 NCBI chr 3:91,607,236...91,775,255
Ensembl chr 3:91,607,305...91,774,683
JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 increases expression EXP lead acetate results in increased expression of HSP90B1 mRNA CTD PMID:17464326 NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,507...80,531,005
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression EXP lead acetate results in increased expression of HSPA5 mRNA CTD PMID:17464326 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,904
JBrowse link
G INHA inhibin subunit alpha multiple interactions EXP lead acetate results in decreased expression of and results in decreased secretion of [INHBB protein binds to INHA protein] CTD PMID:29273543 NCBI chr15:121,581,847...121,586,020
Ensembl chr15:121,580,801...121,586,010
JBrowse link
G INHBB inhibin subunit beta B decreases expression
multiple interactions
EXP lead acetate results in decreased expression of INHBB mRNA
lead acetate results in decreased expression of and results in decreased secretion of [INHBB protein binds to INHA protein]; lead acetate results in decreased expression of and results in decreased secretion of INHBB protein
CTD PMID:29273543 NCBI chr15:30,999,994...31,004,405
Ensembl chr15:30,999,520...31,004,405
JBrowse link
G MTOR mechanistic target of rapamycin kinase increases expression EXP lead acetate results in increased expression of MTOR mRNA CTD PMID:29273543 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888
JBrowse link
lead(2+) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 increases expression EXP Lead results in increased expression of CASP3 CTD PMID:20390873 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,749...45,763,773
JBrowse link
G CCNB1 cyclin B1 increases expression EXP Lead results in increased expression of CCNB1 CTD PMID:20390873 NCBI chr16:47,338,239...47,348,385
Ensembl chr16:47,338,110...47,348,381
JBrowse link
G FSHB follicle stimulating hormone subunit beta multiple interactions EXP [FSHB protein co-treated with Lead co-treated with Mercury] results in decreased secretion of Progesterone CTD PMID:20390873 NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274
JBrowse link
G IGF1 insulin like growth factor 1 increases secretion EXP Lead results in increased secretion of IGF1 protein CTD PMID:20390873 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,037
JBrowse link
G LDHA lactate dehydrogenase A multiple interactions EXP Lead binds to and results in decreased folding of LDHA protein CTD PMID:18501191 NCBI chr 2:40,814,163...40,827,284
Ensembl chr 2:40,812,453...40,826,715
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 880
    chemical entity 880
      molecular entity 878
        inorganic molecular entity 743
          inorganic ion 103
            lead ion 13
              lead cation + 13
Path 2
Term Annotations click to browse term
  CHEBI ontology 880
    subatomic particle 865
      composite particle 865
        hadron 865
          baryon 865
            nucleon 865
              atomic nucleus 865
                atom 865
                  main group element atom 855
                    main group molecular entity 853
                      p-block molecular entity 851
                        carbon group molecular entity 827
                          lead molecular entity 13
                            elemental lead 13
                              lead ion 13
                                lead cation + 13
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.