CHEBI ONTOLOGY - ANNOTATIONS |
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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Term: | EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor |
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Accession: | CHEBI:60186
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browse the term
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Definition: | An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of Ca(2+)-transporting ATPase (EC 3.6.3.8). |
Synonyms: | related_synonym: | ATP phosphohydrolase (Ca(2+)-transporting) inhibitor; ATP phosphohydrolase (Ca(2+)-transporting) inhibitors; Ca(2+)-pumping ATPase inhibitor; Ca(2+)-pumping ATPase inhibitors; Ca(2+)-transporting ATPase (EC 3.6.3.8) inhibitors; Ca(2+)-transporting ATPase inhibitor; Ca(2+)-transporting ATPase inhibitors; SERCA inhibitor; SERCA inhibitors; calcium pump inhibitor; calcium pump inhibitors; plasma membrane Ca-ATPase inhibitor; plasma membrane Ca-ATPase inhibitors; sarco(endo)plasmic reticulum Ca(2+)-ATPase inhibitor; sarco(endo)plasmic reticulum Ca(2+)-ATPase inhibitors; sarcoplasmic reticulum ATPase inhibitor; sarcoplasmic reticulum ATPase inhibitors |
| xref: | Wikipedia:Ca(2%2B)-transporting_atpase |
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Bax |
BCL2 associated X, apoptosis regulator |
increases expression multiple interactions |
ISO |
Bupivacaine results in increased expression of BAX protein 8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one promotes the reaction [[Glucose co-treated with Bupivacaine] results in increased expression of BAX protein]; [Glucose co-treated with Bupivacaine] results in increased expression of BAX protein |
CTD |
PMID:31672611 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2 |
BCL2, apoptosis regulator |
decreases expression multiple interactions |
ISO |
Bupivacaine results in decreased expression of BCL2 protein 8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one promotes the reaction [[Glucose co-treated with Bupivacaine] results in decreased expression of BCL2 protein]; [Glucose co-treated with Bupivacaine] results in decreased expression of BCL2 protein; HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of BCL2 protein] |
CTD |
PMID:31672611 PMID:34793778 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Casp3 |
caspase 3 |
decreases expression increases activity |
ISO EXP |
Bupivacaine results in decreased expression of CASP3 protein Bupivacaine results in increased activity of CASP3 protein |
CTD |
PMID:16109997 PMID:20194319 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp9 |
caspase 9 |
decreases expression |
ISO |
Bupivacaine results in decreased expression of CASP9 protein |
CTD |
PMID:20194319 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
multiple interactions |
EXP |
[Bupivacaine co-treated with Tetrodotoxin co-treated with Dexamethasone] results in decreased expression of CYP3A9 mRNA |
CTD |
PMID:22341215 |
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NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
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Dnm1l |
dynamin 1-like |
decreases expression multiple interactions |
ISO |
Bupivacaine results in decreased expression of DNM1L protein HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of DNM1L protein] |
CTD |
PMID:34793778 |
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NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
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Entpd4 |
ectonucleoside triphosphate diphosphohydrolase 4 |
multiple interactions |
EXP |
[Bupivacaine co-treated with Tetrodotoxin co-treated with Dexamethasone] results in decreased expression of ENTPD4 mRNA |
CTD |
PMID:22341215 |
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NCBI chr15:44,630,873...44,658,706
Ensembl chr15:44,630,873...44,658,706
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H2ax |
H2A.X variant histone |
multiple interactions increases expression |
ISO |
Glucose promotes the reaction [Bupivacaine results in increased expression of H2AX protein] |
CTD |
PMID:31672611 |
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NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
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Hpgds |
hematopoietic prostaglandin D synthase |
increases expression |
ISO |
Bupivacaine results in increased expression of HPGDS mRNA; Bupivacaine results in increased expression of HPGDS protein |
CTD |
PMID:19359520 |
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NCBI chr 4:94,368,426...94,397,931
Ensembl chr 4:94,373,342...94,397,883
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Hrh1 |
histamine receptor H 1 |
affects binding |
ISO |
HRH1 protein binds to Bupivacaine |
CTD |
PMID:32061592 |
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NCBI chr 4:147,564,781...147,649,353
Ensembl chr 4:147,645,995...147,647,455
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Hspa12a |
heat shock protein family A (Hsp70) member 12A |
decreases expression multiple interactions |
ISO |
Bupivacaine results in decreased expression of HSPA12A protein HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of BCL2 protein]; HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of DNM1L protein]; HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of MFN1 protein]; HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of PINK1 protein]; HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of PPARGC1A protein]; HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of PRKN protein]; HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of SLC2A1 protein]; HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of SLC2A4 protein]; HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of TOMM20 protein] |
CTD |
PMID:34793778 |
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NCBI chr 1:257,935,642...258,096,602
Ensembl chr 1:257,935,644...258,096,846
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Itgam |
integrin subunit alpha M |
increases expression multiple interactions |
ISO |
Bupivacaine results in increased expression of ITGAM mRNA 4-benzhydryloxy-1-(3-(1H-tetrazol-5-yl-)-propyl)piperidine inhibits the reaction [Bupivacaine results in increased expression of ITGAM mRNA] |
CTD |
PMID:19359520 |
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NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
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Kcne1 |
potassium voltage-gated channel subfamily E regulatory subunit 1 |
multiple interactions |
ISO |
Bupivacaine results in decreased activity of [KCNQ1 protein binds to KCNE1 protein]; KCNE1 protein inhibits the reaction [KCNQ1 protein mutant form results in increased susceptibility to Bupivacaine] |
CTD |
PMID:16931984 |
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NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
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Kcnk9 |
potassium two pore domain channel subfamily K member 9 |
multiple interactions |
ISO |
Bupivacaine inhibits the reaction [KCNK9 protein results in increased transport of Potassium] |
CTD |
PMID:11249964 |
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NCBI chr 7:104,429,186...104,473,924
Ensembl chr 7:104,437,934...104,473,175
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Kcnq1 |
potassium voltage-gated channel subfamily Q member 1 |
multiple interactions increases response to substance decreases activity |
ISO |
Bupivacaine results in decreased activity of [KCNQ1 protein binds to KCNE1 protein]; KCNE1 protein inhibits the reaction [KCNQ1 protein mutant form results in increased susceptibility to Bupivacaine] Bupivacaine results in decreased activity of KCNQ1 protein |
CTD |
PMID:16931984 |
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NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
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Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation multiple interactions |
ISO |
Bupivacaine results in increased phosphorylation of MAPK1 protein Glucose promotes the reaction [Bupivacaine results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:34060177 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3 |
mitogen activated protein kinase 3 |
increases phosphorylation multiple interactions |
ISO |
Bupivacaine results in increased phosphorylation of MAPK3 protein Glucose promotes the reaction [Bupivacaine results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:34060177 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mfn1 |
mitofusin 1 |
decreases expression multiple interactions |
ISO |
Bupivacaine results in decreased expression of MFN1 protein HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of MFN1 protein] |
CTD |
PMID:34793778 |
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NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
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Myf5 |
myogenic factor 5 |
decreases expression |
EXP |
Bupivacaine results in decreased expression of MYF5 protein |
CTD |
PMID:10434046 |
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NCBI chr 7:42,802,946...42,806,177
Ensembl chr 7:42,802,946...42,806,177
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Myod1 |
myogenic differentiation 1 |
decreases expression |
EXP |
Bupivacaine results in decreased expression of MYOD1 protein |
CTD |
PMID:10434046 |
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NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554
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Myog |
myogenin |
decreases expression |
EXP |
Bupivacaine results in decreased expression of MYOG protein |
CTD |
PMID:10434046 |
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NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039
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Pink1 |
PTEN induced kinase 1 |
decreases expression multiple interactions |
ISO |
Bupivacaine results in decreased expression of PINK1 protein HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of PINK1 protein] |
CTD |
PMID:34793778 |
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NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
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Ppargc1a |
PPARG coactivator 1 alpha |
increases expression multiple interactions decreases expression |
ISO |
Bupivacaine results in increased expression of PPARGC1A mRNA HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of PPARGC1A protein] |
CTD |
PMID:34793778 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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Prkcb |
protein kinase C, beta |
multiple interactions |
EXP |
[Bupivacaine co-treated with Tetrodotoxin co-treated with Dexamethasone] results in decreased expression of PRKCB mRNA |
CTD |
PMID:22341215 |
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NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
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Prkn |
parkin RBR E3 ubiquitin protein ligase |
decreases expression multiple interactions |
ISO |
Bupivacaine results in decreased expression of PRKN protein HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of PRKN protein] |
CTD |
PMID:34793778 |
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NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
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Ptgdr |
prostaglandin D2 receptor |
affects expression |
ISO |
Bupivacaine affects the expression of PTGDR mRNA |
CTD |
PMID:19359520 |
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NCBI chr15:17,360,304...17,367,679
Ensembl chr15:17,360,304...17,367,679
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Ptgs1 |
prostaglandin-endoperoxide synthase 1 |
increases expression |
ISO |
Bupivacaine results in increased expression of PTGS1 mRNA |
CTD |
PMID:18165598 |
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NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
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Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression multiple interactions |
ISO |
Bupivacaine results in increased expression of PTGS2 mRNA [Bupivacaine results in increased expression of PTGS2] which results in increased abundance of Dinoprostone |
CTD |
PMID:18165598 |
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NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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Slc2a1 |
solute carrier family 2 member 1 |
decreases expression multiple interactions |
ISO |
Bupivacaine results in decreased expression of SLC2A1 protein HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of SLC2A1 protein] |
CTD |
PMID:34793778 |
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NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
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Slc2a4 |
solute carrier family 2 member 4 |
multiple interactions decreases expression |
ISO |
HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of SLC2A4 protein] |
CTD |
PMID:34793778 |
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NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
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Slc6a2 |
solute carrier family 6 member 2 |
multiple interactions |
ISO |
Bupivacaine inhibits the reaction [[Desipramine results in decreased activity of SLC6A2 protein] which results in decreased abundance of Norepinephrine] |
CTD |
PMID:16725121 |
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NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357
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Tomm20 |
translocase of outer mitochondrial membrane 20 |
decreases expression multiple interactions |
ISO |
Bupivacaine results in decreased expression of TOMM20 protein HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of TOMM20 protein] |
CTD |
PMID:34793778 |
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NCBI chr19:54,925,197...54,935,188
Ensembl chr19:54,923,402...54,935,198
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Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
increases activity multiple interactions |
EXP |
Bupivacaine results in increased activity of TRPV1 protein Bupivacaine affects the reaction [Capsaicin results in increased activity of TRPV1 protein] |
CTD |
PMID:15854744 PMID:18172555 |
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NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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Xrcc6 |
X-ray repair cross complementing 6 |
increases expression multiple interactions |
ISO |
Bupivacaine results in increased expression of XRCC6 protein 8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one inhibits the reaction [[Glucose co-treated with Bupivacaine] results in increased expression of XRCC6 protein]; [Glucose co-treated with Bupivacaine] results in increased expression of XRCC6 protein; Glucose inhibits the reaction [Bupivacaine results in increased expression of XRCC6 protein] |
CTD |
PMID:31672611 |
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NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762
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Aars1 |
alanyl-tRNA synthetase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of AARS protein |
CTD |
PMID:24648495 |
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NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
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Abcb1a |
ATP binding cassette subfamily B member 1A |
decreases expression multiple interactions |
ISO |
Thapsigargin results in decreased expression of ABCB1 mRNA; Thapsigargin results in decreased expression of ABCB1 protein 1-(4-chlorophenyl)-3-(3-(4-chlorophenyl)-5,5-dimethyl-1-(3-(5-nitrofuran-2-yl)allyldienehydrazinocarbonylmethyl)-2-oxoimidazolidin-4-yl)-1-hydroxyurea inhibits the reaction [Thapsigargin results in decreased expression of ABCB1 protein] |
CTD |
PMID:34915026 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Acad11 |
acyl-CoA dehydrogenase family, member 11 |
increases expression |
ISO |
Thapsigargin results in increased expression of ACAD11 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 8:104,681,346...104,746,559
Ensembl chr 8:104,681,396...104,746,560
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Acad9 |
acyl-CoA dehydrogenase family, member 9 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ACAD9 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 2:118,943,170...118,966,150
Ensembl chr 2:118,943,174...118,966,547
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Acadvl |
acyl-CoA dehydrogenase, very long chain |
increases expression |
ISO |
Thapsigargin results in increased expression of ACADVL mRNA |
CTD |
PMID:22378314 |
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NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
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Acat2 |
acetyl-CoA acetyltransferase 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ACAT2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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Acbd3 |
acyl-CoA binding domain containing 3 |
increases expression |
ISO |
Thapsigargin results in increased expression of ACBD3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr13:92,455,813...92,484,556
Ensembl chr13:92,455,655...92,483,380
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Ackr1 |
atypical chemokine receptor 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ACKR1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr13:85,782,396...85,786,002
Ensembl chr13:85,782,398...85,783,983
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Acly |
ATP citrate lyase |
increases expression |
ISO |
Thapsigargin results in increased expression of ACLY protein |
CTD |
PMID:24648495 |
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NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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Aco2 |
aconitase 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of ACO2 protein |
CTD |
PMID:24648495 |
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NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
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Acot13 |
acyl-CoA thioesterase 13 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ACOT13 mRNA |
CTD |
PMID:22378314 |
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NCBI chr17:40,240,378...40,252,851
Ensembl chr17:40,240,378...40,252,851
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Acot7 |
acyl-CoA thioesterase 7 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ACOT7 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 5:162,686,562...162,779,309
Ensembl chr 5:162,684,645...162,779,309
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Acta2 |
actin alpha 2, smooth muscle |
increases expression decreases expression |
ISO |
Thapsigargin results in increased expression of ACTA2 mRNA Thapsigargin results in decreased expression of ACTA2 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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Actg1 |
actin, gamma 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ACTG1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
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Actn1 |
actinin, alpha 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ACTN1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251
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Acvr1 |
activin A receptor type 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ACVR1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241
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Adamts4 |
ADAM metallopeptidase with thrombospondin type 1 motif, 4 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ADAMTS4 mRNA |
CTD |
PMID:22378314 |
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NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065
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Adamts9 |
ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ADAMTS9 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929
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Adhfe1 |
alcohol dehydrogenase, iron containing, 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ADHFE1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517
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Adi1 |
acireductone dioxygenase 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ADI1 protein |
CTD |
PMID:24648495 |
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NCBI chr 6:45,306,885...45,313,847
Ensembl chr 6:45,306,841...45,313,842
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Adm |
adrenomedullin |
decreases expression increases expression |
ISO |
Thapsigargin results in decreased expression of ADM mRNA Thapsigargin results in increased expression of ADM mRNA |
CTD |
PMID:20682585 PMID:22378314 |
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NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
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Adm2 |
adrenomedullin 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of ADM2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 7:120,393,219...120,394,965
Ensembl chr 7:120,393,179...120,396,331
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Adra2a |
adrenoceptor alpha 2A |
multiple interactions |
ISO |
Thapsigargin inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein] |
CTD |
PMID:10742289 |
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NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
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Afap1 |
actin filament associated protein 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of AFAP1 protein |
CTD |
PMID:24648495 |
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NCBI chr14:74,743,322...74,856,295
Ensembl chr14:74,743,320...74,856,263
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Afdn |
afadin, adherens junction formation factor |
increases expression |
ISO |
Thapsigargin results in increased expression of AFDN protein |
CTD |
PMID:24648495 |
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NCBI chr 1:53,884,711...54,034,216
Ensembl chr 1:53,905,373...54,034,216
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Ago3 |
argonaute RISC catalytic component 3 |
multiple interactions affects localization |
ISO |
Cycloheximide inhibits the reaction [Thapsigargin affects the localization of AGO3 mRNA]; Emetine inhibits the reaction [Thapsigargin affects the localization of AGO3 mRNA] |
CTD |
PMID:29576526 |
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NCBI chr 5:138,632,367...138,714,230
Ensembl chr 5:138,639,569...138,714,230
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G |
Ahnak |
AHNAK nucleoprotein |
increases expression |
ISO |
Thapsigargin results in increased expression of AHNAK mRNA |
CTD |
PMID:19442820 |
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NCBI chr 1:205,882,223...205,970,934
Ensembl chr 1:205,882,273...205,970,926
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
Thapsigargin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] |
CTD |
PMID:15364539 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Ak2 |
adenylate kinase 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of AK2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 5:141,308,650...141,364,633
Ensembl chr 5:141,346,063...141,364,632
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G |
Ak3 |
adenylate kinase 3 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of AK3 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625
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G |
Ak4 |
adenylate kinase 4 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of AK4 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
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G |
Akap17a |
A-kinase anchoring protein 17A |
increases expression |
ISO |
Thapsigargin results in increased expression of AKAP17A mRNA |
CTD |
PMID:22378314 |
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NCBI chr12:16,310,427...16,315,166
Ensembl chr12:16,310,437...16,314,479
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G |
Akap8l |
A-kinase anchoring protein 8 like |
increases expression |
ISO |
Thapsigargin results in increased expression of AKAP8L protein |
CTD |
PMID:24648495 |
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NCBI chr 7:11,332,671...11,362,287
Ensembl chr 7:11,332,672...11,362,275
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G |
Akirin1 |
akirin 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of AKIRIN1 protein |
CTD |
PMID:24648495 |
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NCBI chr 5:135,989,378...136,004,782
Ensembl chr 5:135,989,465...136,004,762
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G |
Akna |
AT-hook transcription factor |
increases expression |
ISO |
Thapsigargin results in increased expression of AKNA mRNA |
CTD |
PMID:22378314 |
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NCBI chr 5:76,777,415...76,824,380
Ensembl chr 5:76,777,415...76,816,017
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions increases phosphorylation decreases expression decreases phosphorylation |
ISO EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Thapsigargin results in increased phosphorylation of AKT1 protein]; NRF1 protein inhibits the reaction [Thapsigargin results in decreased phosphorylation of AKT1 protein]; TFAM protein inhibits the reaction [Thapsigargin results in decreased phosphorylation of AKT1 protein] Thapsigargin results in decreased expression of AKT1 protein modified form [Thapsigargin co-treated with HRAS protein] results in increased phosphorylation of AKT1 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Thapsigargin results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Thapsigargin results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:15339911 PMID:16338971 PMID:22378314 PMID:24898257 PMID:25398788 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Aktip |
AKT interacting protein |
decreases expression |
ISO |
Thapsigargin results in decreased expression of AKTIP protein |
CTD |
PMID:24648495 |
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NCBI chr19:15,866,811...15,877,123
Ensembl chr19:15,866,928...15,886,663
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G |
Alcam |
activated leukocyte cell adhesion molecule |
increases expression |
ISO |
Thapsigargin results in increased expression of ALCAM mRNA |
CTD |
PMID:22378314 |
|
NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954
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G |
Aldh18a1 |
aldehyde dehydrogenase 18 family, member A1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ALDH18A1 protein |
CTD |
PMID:24648495 |
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NCBI chr 1:239,375,657...239,407,967
Ensembl chr 1:239,375,669...239,407,890
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G |
Aldh1a2 |
aldehyde dehydrogenase 1 family, member A2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ALDH1A2 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107
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G |
Aldh1a3 |
aldehyde dehydrogenase 1 family, member A3 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ALDH1A3 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
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G |
Aldh5a1 |
aldehyde dehydrogenase 5 family, member A1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ALDH5A1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677
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G |
Aldh6a1 |
aldehyde dehydrogenase 6 family, member A1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ALDH6A1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
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G |
Aldoc |
aldolase, fructose-bisphosphate C |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ALDOC mRNA |
CTD |
PMID:22378314 |
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NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
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G |
Alg5 |
ALG5, dolichyl-phosphate beta-glucosyltransferase |
increases expression |
ISO |
Thapsigargin results in increased expression of ALG5 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
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NCBI chr 2:138,936,998...138,951,228
Ensembl chr 2:138,936,993...138,951,216
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G |
Alox5 |
arachidonate 5-lipoxygenase |
multiple interactions |
ISO |
1-Butanol inhibits the reaction [Thapsigargin results in increased activity of and results in increased localization of ALOX5 protein]; 1-oleoyl-2-acetoyl-sn-glycerol inhibits the reaction [1-Butanol inhibits the reaction [Thapsigargin results in increased activity of and results in increased localization of ALOX5 protein]]; SB 203580 inhibits the reaction [Thapsigargin results in increased phosphorylation of and results in increased activity of ALOX5 protein]; Thapsigargin results in increased activity of and results in increased localization of ALOX5 protein; Thapsigargin results in increased phosphorylation of and results in increased activity of ALOX5 protein |
CTD |
PMID:10779545 PMID:18218859 |
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NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
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G |
Alpp |
alkaline phosphatase, placental |
increases expression |
ISO |
Thapsigargin results in increased expression of ALPP mRNA |
CTD |
PMID:29453283 |
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NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606
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G |
Amot |
angiomotin |
decreases expression |
ISO |
Thapsigargin results in decreased expression of AMOT mRNA |
CTD |
PMID:29453283 |
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NCBI chr X:108,982,399...109,041,265
Ensembl chr X:108,984,022...109,041,272
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G |
Amt |
aminomethyltransferase |
increases expression |
ISO |
Thapsigargin results in increased expression of AMT mRNA |
CTD |
PMID:22378314 |
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NCBI chr 8:108,981,620...108,988,127
Ensembl chr 8:108,976,472...108,988,126
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G |
Angptl2 |
angiopoietin-like 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ANGPTL2 protein |
CTD |
PMID:24648495 |
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NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178
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G |
Angptl3 |
angiopoietin-like 3 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ANGPTL3 mRNA |
CTD |
PMID:32535746 |
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NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957
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G |
Ankrd10 |
ankyrin repeat domain 10 |
increases expression |
ISO |
Thapsigargin results in increased expression of ANKRD10 mRNA |
CTD |
PMID:29453283 |
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NCBI chr16:77,866,489...77,889,745
Ensembl chr16:77,864,261...77,889,745
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G |
Ankrd17 |
ankyrin repeat domain 17 |
increases expression |
ISO |
Thapsigargin results in increased expression of ANKRD17 protein |
CTD |
PMID:24648495 |
|
NCBI chr14:17,723,239...17,862,625
Ensembl chr14:17,721,932...17,862,617
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G |
Antxr2 |
ANTXR cell adhesion molecule 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of ANTXR2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr14:11,542,266...11,682,112
Ensembl chr14:11,541,772...11,682,094
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G |
Anxa5 |
annexin A5 |
increases expression |
ISO |
Thapsigargin results in increased expression of ANXA5 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
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G |
Ap2m1 |
adaptor related protein complex 2 subunit mu 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of AP2M1 protein |
CTD |
PMID:24648495 |
|
NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
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G |
Ap3b1 |
adaptor related protein complex 3 subunit beta 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of AP3B1 protein |
CTD |
PMID:24648495 |
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NCBI chr 2:25,600,069...25,800,937
Ensembl chr 2:25,600,040...25,800,935
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G |
Apob |
apolipoprotein B |
decreases secretion decreases expression |
ISO |
Thapsigargin results in decreased secretion of APOB protein Thapsigargin results in decreased expression of APOB mRNA |
CTD |
PMID:32535746 |
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NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
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G |
Apoc3 |
apolipoprotein C3 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of APOC3 mRNA |
CTD |
PMID:32535746 |
|
NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
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G |
Aqr |
aquarius intron-binding spliceosomal factor |
increases expression |
ISO |
Thapsigargin results in increased expression of AQR protein |
CTD |
PMID:24648495 |
|
NCBI chr 3:100,874,987...100,945,026
Ensembl chr 3:100,874,987...100,945,044
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G |
Ar |
androgen receptor |
multiple interactions |
ISO |
Thapsigargin results in increased degradation of and results in decreased expression of AR protein |
CTD |
PMID:30280407 |
|
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Arcn1 |
archain 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ARCN1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 8:45,057,617...45,082,224
Ensembl chr 8:45,057,619...45,082,247
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G |
Arf3 |
ADP-ribosylation factor 3 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ARF3 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 7:129,886,082...129,912,022
Ensembl chr 7:129,886,082...129,912,002
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G |
Arf4 |
ADP-ribosylation factor 4 |
increases expression |
ISO |
Thapsigargin results in increased expression of ARF4 mRNA |
CTD |
PMID:22378314 |
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NCBI chr16:1,896,692...1,913,267
Ensembl chr16:1,896,546...1,913,261
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G |
Arfgap3 |
ADP-ribosylation factor GTPase activating protein 3 |
increases expression |
ISO |
Thapsigargin results in increased expression of ARFGAP3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 7:114,432,873...114,479,206
Ensembl chr 7:114,432,873...114,479,208
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G |
Arg2 |
arginase 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ARG2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
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G |
Arhgef2 |
Rho/Rac guanine nucleotide exchange factor 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of ARHGEF2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355
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G |
Arid4a |
AT-rich interaction domain 4A |
increases expression |
ISO |
Thapsigargin results in increased expression of ARID4A protein |
CTD |
PMID:24648495 |
|
NCBI chr 6:89,522,463...89,593,868
Ensembl chr 6:89,522,442...89,593,510
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G |
Arid4b |
AT-rich interaction domain 4B |
increases expression |
ISO |
Thapsigargin results in increased expression of ARID4B protein |
CTD |
PMID:24648495 |
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NCBI chr17:51,138,419...51,262,956
Ensembl chr17:51,138,535...51,262,906
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G |
Arl1 |
ADP-ribosylation factor like GTPase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ARL1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898
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G |
Armcx1 |
armadillo repeat containing, X-linked 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ARMCX1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr X:97,898,969...97,902,874
Ensembl chr X:97,898,883...97,903,299
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G |
Armcx3 |
armadillo repeat containing, X-linked 3 |
increases expression |
ISO |
Thapsigargin results in increased expression of ARMCX3 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr X:97,937,115...97,942,098
Ensembl chr X:97,936,999...97,942,098
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G |
Arpc3 |
actin related protein 2/3 complex, subunit 3 |
increases expression |
ISO |
Thapsigargin results in increased expression of ARPC3 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr12:34,172,780...34,186,651
Ensembl chr12:34,172,780...34,186,651
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G |
Asb5 |
ankyrin repeat and SOCS box-containing 5 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ASB5 protein |
CTD |
PMID:24648495 |
|
NCBI chr16:37,237,869...37,305,207
Ensembl chr16:37,235,405...37,278,109
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G |
Ascl1 |
achaete-scute family bHLH transcription factor 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ASCL1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 7:21,904,153...21,906,003
Ensembl chr 7:21,903,126...21,905,993
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G |
Asf1b |
anti-silencing function 1B histone chaperone |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ASF1B mRNA |
CTD |
PMID:22378314 |
|
NCBI chr19:24,181,024...24,195,604
Ensembl chr19:24,181,028...24,195,549
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G |
Asgr1 |
asialoglycoprotein receptor 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ASGR1 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr10:54,775,727...54,779,642
Ensembl chr10:54,776,024...54,779,631
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G |
Asns |
asparagine synthetase (glutamine-hydrolyzing) |
increases expression |
ISO |
Thapsigargin results in increased expression of ASNS mRNA |
CTD |
PMID:22378314 PMID:29453283 |
|
NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
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G |
Asph |
aspartate-beta-hydroxylase |
increases expression |
ISO |
Thapsigargin results in increased expression of ASPH protein |
CTD |
PMID:24648495 |
|
NCBI chr 5:22,603,879...22,814,107
Ensembl chr 5:22,603,486...22,813,876
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G |
Atad2 |
ATPase family, AAA domain containing 2 |
decreases expression increases expression |
ISO |
Thapsigargin results in decreased expression of ATAD2 mRNA Thapsigargin results in increased expression of ATAD2 protein |
CTD |
PMID:22378314 PMID:24648495 |
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NCBI chr 7:89,634,123...89,676,738
Ensembl chr 7:89,634,123...89,676,738
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G |
Atf3 |
activating transcription factor 3 |
multiple interactions increases expression |
ISO EXP |
ATF3 mutant form promotes the reaction [Thapsigargin results in increased expression of PMAIP1 mRNA] Thapsigargin results in increased expression of ATF3 mRNA; Thapsigargin results in increased expression of ATF3 protein |
CTD |
PMID:17332266 PMID:20022965 PMID:21694771 PMID:22641616 PMID:22935518 PMID:29453283 PMID:33770205 More...
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NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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G |
Atf4 |
activating transcription factor 4 |
multiple interactions decreases response to substance increases activity increases expression |
ISO EXP |
ATF4 mutant form inhibits the reaction [Thapsigargin results in increased expression of PMAIP1 mRNA]; ATF4 mutant form inhibits the reaction [Thapsigargin results in increased expression of PMAIP1 protein]; Dactinomycin inhibits the reaction [Thapsigargin results in increased expression of ATF4 mRNA]; Dactinomycin inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; Doxorubicin inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; NUPR1 mutant form promotes the reaction [Thapsigargin results in increased expression of ATF4 mRNA]; Thapsigargin promotes the reaction [ATF4 protein binds to PMAIP1 promoter] ATF4 results in decreased susceptibility to Thapsigargin Thapsigargin results in increased activity of ATF4 protein Thapsigargin results in increased expression of ATF4 mRNA; Thapsigargin results in increased expression of ATF4 protein 2-aminoethoxydiphenyl borate inhibits the reaction [Thapsigargin results in increased expression of ATF4 mRNA]; 2-aminoethoxydiphenyl borate inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; ATF4 gene mutant form inhibits the reaction [Thapsigargin results in increased expression of IBTK mRNA alternative form]; Dantrolene inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; Dantrolene promotes the reaction [Thapsigargin results in increased expression of ATF4 mRNA]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of ATF4 mRNA]; GSK2656157 inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein] 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; salubrinal promotes the reaction [Thapsigargin results in increased expression of ATF4 protein] |
CTD |
PMID:16298333 PMID:17283163 PMID:20022965 PMID:20589738 PMID:22378314 PMID:23383089 PMID:24648495 PMID:24865413 PMID:27226639 PMID:27358234 PMID:27587023 PMID:28223344 PMID:28844859 PMID:29109149 PMID:32357311 PMID:32578922 More...
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Atf5 |
activating transcription factor 5 |
increases expression |
ISO |
Thapsigargin results in increased expression of ATF5 mRNA Thapsigargin results in increased expression of ATF5 mRNA; Thapsigargin results in increased expression of ATF5 protein |
CTD |
PMID:22378314 PMID:24648495 PMID:28942281 |
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NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
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G |
Atf6 |
activating transcription factor 6 |
multiple interactions increases cleavage increases expression increases activity |
ISO EXP |
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased expression of ATF6 protein]; Apigenin inhibits the reaction [Thapsigargin results in increased cleavage of ATF6 protein] Thapsigargin results in increased activity of ATF6 protein 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased expression of ATF6 protein]; ATF6 promotes the reaction [Thapsigargin results in increased expression of DDIT3 protein]; ATF6 promotes the reaction [Thapsigargin results in increased expression of HSPA5 protein]; demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased expression of ATF6 protein]; Luteolin inhibits the reaction [Thapsigargin results in increased expression of ATF6 protein modified form]; Thapsigargin results in increased cleavage of and affects the localization of ATF6 protein Thapsigargin results in increased expression of ATF6 mRNA; Thapsigargin results in increased expression of ATF6 protein Thapsigargin results in increased expression of ATF6 mRNA; Thapsigargin results in increased expression of ATF6 protein; Thapsigargin results in increased expression of ATF6 protein modified form |
CTD |
PMID:17963750 PMID:18477628 PMID:20493918 PMID:22378314 PMID:23383089 PMID:23576437 PMID:24638036 PMID:26264395 PMID:27358234 PMID:27587023 PMID:28223344 PMID:30796460 PMID:32407927 More...
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NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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G |
Atg10 |
autophagy related 10 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ATG10 protein |
CTD |
PMID:24648495 |
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NCBI chr 2:22,109,304...22,398,313
Ensembl chr 2:22,108,426...22,398,233
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G |
Atp1b1 |
ATPase Na+/K+ transporting subunit beta 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ATP1B1 mRNA |
CTD |
PMID:33770205 |
|
NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
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G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
affects response to substance multiple interactions decreases activity increases expression |
ISO EXP |
ATP2A2 protein affects the susceptibility to Thapsigargin [Thapsigargin results in decreased activity of ATP2A2 protein] which results in decreased transport of Calcium; Tetradecanoylphorbol Acetate inhibits the reaction [Thapsigargin results in increased expression of ATP2A2 mRNA]; Thapsigargin results in increased expression of and results in decreased activity of ATP2A2 protein |
CTD |
PMID:17287366 PMID:17475205 PMID:19244478 PMID:20816668 |
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NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
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G |
Atp2a3 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 |
multiple interactions |
ISO |
[Thapsigargin co-treated with Ionomycin] promotes the reaction [STIM1 protein binds to ATP2A3 protein] |
CTD |
PMID:18439569 |
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NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748
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G |
Atp5f1a |
ATP synthase F1 subunit alpha |
increases expression |
ISO |
Thapsigargin results in increased expression of ATP5F1A mRNA |
CTD |
PMID:22378314 |
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NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
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G |
Atp5mc1 |
ATP synthase membrane subunit c locus 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ATP5MC1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr10:81,024,056...81,026,780
Ensembl chr10:81,023,925...81,027,124 Ensembl chr10:81,023,925...81,027,124
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G |
Atp5mc3 |
ATP synthase membrane subunit c locus 3 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ATP5MC3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 3:58,810,535...58,813,185
Ensembl chr 3:58,810,535...58,814,279
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G |
Atp5mf |
ATP synthase membrane subunit f |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ATP5MF mRNA |
CTD |
PMID:22378314 |
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NCBI chr12:9,421,665...9,428,236
Ensembl chr12:9,421,579...9,428,236
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G |
Atp6v0a1 |
ATPase H+ transporting V0 subunit a1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ATP6V0A1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr10:85,935,802...85,989,901
Ensembl chr10:85,935,854...85,989,895
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G |
Atp6v0a2 |
ATPase H+ transporting V0 subunit a2 |
increases expression |
ISO |
Thapsigargin results in increased expression of ATP6V0A2 mRNA |
CTD |
PMID:29453283 |
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NCBI chr12:31,949,863...31,979,777
Ensembl chr12:31,822,733...32,007,069
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G |
Atp6v0d2 |
ATPase H+ transporting V0 subunit D2 |
multiple interactions decreases expression |
ISO |
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of ATP6V0D2 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of ATP6V0D2 mRNA] |
CTD |
PMID:19442820 |
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NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354
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G |
Atp8a1 |
ATPase phospholipid transporting 8A1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ATP8A1 protein |
CTD |
PMID:24648495 |
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NCBI chr14:40,315,013...40,557,572
Ensembl chr14:40,315,049...40,554,611
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G |
Atrx |
ATRX, chromatin remodeler |
increases expression |
ISO |
Thapsigargin results in increased expression of ATRX protein |
CTD |
PMID:24648495 |
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NCBI chr X:70,850,981...70,997,330
Ensembl chr X:70,850,981...70,997,330
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G |
Auh |
AU RNA binding methylglutaconyl-CoA hydratase |
increases expression |
ISO |
Thapsigargin results in increased expression of AUH mRNA |
CTD |
PMID:22378314 |
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NCBI chr17:12,329,522...12,424,896
Ensembl chr17:12,329,524...12,424,896
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G |
Aurkb |
aurora kinase B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of AURKB mRNA |
CTD |
PMID:22378314 |
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NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
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G |
Aven |
apoptosis and caspase activation inhibitor |
increases expression |
ISO |
Thapsigargin results in increased expression of AVEN mRNA |
CTD |
PMID:29453283 |
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NCBI chr 3:99,299,009...99,431,635
Ensembl chr 3:99,298,930...99,431,634
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G |
B4galt5 |
beta-1,4-galactosyltransferase 5 |
increases expression |
ISO |
Thapsigargin results in increased expression of B4GALT5 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 3:156,018,056...156,033,983
Ensembl chr 3:156,018,053...156,070,074
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G |
Bach2 |
BTB domain and CNC homolog 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of BACH2 mRNA |
CTD |
PMID:24247028 |
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NCBI chr 5:46,632,338...46,982,676
Ensembl chr 5:46,638,317...46,977,877
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Bad |
BCL2-associated agonist of cell death |
increases expression |
ISO |
Thapsigargin results in increased expression of BAD mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Banf1 |
BAF nuclear assembly factor 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BANF1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:202,672,170...202,674,215
Ensembl chr 1:202,671,305...202,674,188
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G |
Basp1 |
brain abundant, membrane attached signal protein 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BASP1 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
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NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043
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G |
Bax |
BCL2 associated X, apoptosis regulator |
increases activity multiple interactions increases expression |
ISO |
Thapsigargin results in increased activity of BAX protein Thapsigargin promotes the reaction [arsenite results in increased expression of BAX protein] Thapsigargin results in increased expression of BAX protein |
CTD |
PMID:20130848 PMID:26677073 PMID:35033536 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Baz1a |
bromodomain adjacent to zinc finger domain, 1A |
increases expression |
ISO |
Thapsigargin results in increased expression of BAZ1A protein |
CTD |
PMID:24648495 |
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NCBI chr 6:72,389,701...72,512,516
Ensembl chr 6:72,389,703...72,512,459
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G |
Baz1b |
bromodomain adjacent to zinc finger domain, 1B |
increases expression |
ISO |
Thapsigargin results in increased expression of BAZ1B protein |
CTD |
PMID:24648495 |
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NCBI chr12:21,431,985...21,489,956
Ensembl chr12:21,431,985...21,490,426
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G |
Bbc3 |
Bcl-2 binding component 3 |
increases expression |
ISO |
Thapsigargin results in increased expression of BBC3 mRNA |
CTD |
PMID:16018998 PMID:22378314 |
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NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
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G |
Bcas2 |
BCAS2, pre-mRNA processing factor |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BCAS2 protein |
CTD |
PMID:24648495 |
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NCBI chr 2:190,692,503...190,700,386
Ensembl chr 2:190,692,461...190,700,389
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G |
Bcat1 |
branched chain amino acid transaminase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of BCAT1 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
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NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
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G |
Bcat2 |
branched chain amino acid transaminase 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of BCAT2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
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G |
Bckdk |
branched chain ketoacid dehydrogenase kinase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BCKDK mRNA Thapsigargin results in decreased expression of BCKDK protein |
CTD |
PMID:22378314 PMID:24648495 |
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NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633
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G |
Bcl2 |
BCL2, apoptosis regulator |
increases expression decreases expression decreases phosphorylation multiple interactions |
ISO |
Thapsigargin results in increased expression of BCL2 mRNA Thapsigargin results in decreased expression of BCL2 protein Thapsigargin results in decreased phosphorylation of BCL2 protein Thapsigargin promotes the reaction [arsenite results in decreased expression of BCL2 protein] 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Thapsigargin results in decreased expression of BCL2 protein]; O-1602 compound inhibits the reaction [Thapsigargin results in decreased expression of BCL2 protein] |
CTD |
PMID:22378314 PMID:25611565 PMID:26677073 PMID:30841431 PMID:35033536 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
multiple interactions affects splicing increases expression decreases expression |
EXP ISO |
6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one inhibits the reaction [Thapsigargin affects the splicing of BCL2L1 mRNA]; GW 4869 inhibits the reaction [Thapsigargin affects the splicing of BCL2L1 mRNA]; PLA2G6 mutant form inhibits the reaction [Thapsigargin affects the splicing of BCL2L1 mRNA] Thapsigargin results in increased expression of BCL2L1 protein BCL2L1 protein inhibits the reaction [Thapsigargin results in increased expression of ERN1 protein]; BCL2L1 protein inhibits the reaction [Thapsigargin results in increased expression of XBP1 protein alternative form] 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Thapsigargin results in decreased expression of BCL2L1 protein]; O-1602 compound inhibits the reaction [Thapsigargin results in decreased expression of BCL2L1 protein] |
CTD |
PMID:23885834 PMID:25762722 PMID:30841431 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Bclaf1 |
BCL2-associated transcription factor 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of BCLAF1 protein |
CTD |
PMID:24648495 |
|
NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832
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G |
Begain |
brain-enriched guanylate kinase-associated |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BEGAIN mRNA |
CTD |
PMID:22378314 |
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NCBI chr 6:127,943,651...127,979,876
Ensembl chr 6:127,943,651...127,979,841
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G |
Bend6 |
BEN domain containing 6 |
increases expression |
ISO |
Thapsigargin results in increased expression of BEND6 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 9:36,081,033...36,135,309
Ensembl chr 9:36,081,484...36,135,228
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G |
Best1 |
bestrophin 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of BEST1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:206,629,340...206,646,085
Ensembl chr 1:206,629,500...206,646,063
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G |
Bet1 |
Bet1 golgi vesicular membrane trafficking protein |
decreases expression multiple interactions |
ISO |
Thapsigargin results in decreased expression of BET1 mRNA [Thapsigargin co-treated with 4-methoxycinnamate methyl ester] results in decreased expression of BET1 mRNA |
CTD |
PMID:19442820 |
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NCBI chr 4:32,116,232...32,126,592
Ensembl chr 4:32,116,235...32,126,617
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G |
Bet1l |
Bet1 golgi vesicular membrane trafficking protein-like |
increases expression |
ISO |
Thapsigargin results in increased expression of BET1L mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:195,930,165...195,935,072
Ensembl chr 1:195,931,411...195,935,040
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G |
Bex2 |
brain expressed X-linked 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of BEX2 mRNA |
CTD |
PMID:29453283 |
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NCBI chr X:99,219,015...99,220,411
Ensembl chr X:99,219,014...99,220,958
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G |
Bhlhe40 |
basic helix-loop-helix family, member e40 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BHLHE40 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
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G |
Bid |
BH3 interacting domain death agonist |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BID mRNA |
CTD |
PMID:22378314 |
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NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Birc2 |
baculoviral IAP repeat-containing 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BIRC2 protein |
CTD |
PMID:16382148 |
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NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
multiple interactions increases expression |
ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Thapsigargin results in increased expression of BIRC3 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Thapsigargin results in increased expression of BIRC3 protein] Thapsigargin results in increased expression of BIRC3 mRNA; Thapsigargin results in increased expression of BIRC3 protein |
CTD |
PMID:15339911 |
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NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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G |
Blm |
BLM RecQ like helicase |
increases expression |
ISO |
Thapsigargin results in increased expression of BLM protein |
CTD |
PMID:24648495 |
|
NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
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G |
Blnk |
B-cell linker |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BLNK protein |
CTD |
PMID:24648495 |
|
NCBI chr 1:239,753,640...239,821,113
Ensembl chr 1:239,753,648...239,821,113
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G |
Bloc1s2 |
biogenesis of lysosomal organelles complex-1, subunit 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of BLOC1S2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:243,024,611...243,031,749
Ensembl chr 1:243,024,614...243,031,653
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G |
Bmf |
Bcl2 modifying factor |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BMF mRNA |
CTD |
PMID:33770205 |
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NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
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G |
Bmp2k |
BMP-2 inducible kinase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BMP2K protein |
CTD |
PMID:24648495 |
|
NCBI chr14:12,481,194...12,579,411
Ensembl chr14:12,484,729...12,579,134
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G |
Bms1 |
BMS1 ribosome biogenesis factor |
increases expression |
ISO |
Thapsigargin results in increased expression of BMS1 protein |
CTD |
PMID:24648495 |
|
NCBI chr 4:151,558,163...151,595,187
Ensembl chr 4:151,558,163...151,595,127
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G |
Bnc2 |
basonuclin 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BNC2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 5:98,679,071...99,079,742
Ensembl chr 5:98,687,410...99,079,426
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G |
Bnip3 |
BCL2 interacting protein 3 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BNIP3 mRNA Thapsigargin results in decreased expression of BNIP3 protein |
CTD |
PMID:22378314 PMID:24648495 |
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NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
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G |
Bola3 |
bolA family member 3 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BOLA3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 4:115,853,350...115,862,797
Ensembl chr 4:115,853,350...115,862,797
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G |
Bphl |
biphenyl hydrolase like |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BPHL mRNA |
CTD |
PMID:22378314 |
|
NCBI chr17:30,800,939...30,837,277
Ensembl chr17:30,799,629...30,837,288
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G |
Brca1 |
BRCA1, DNA repair associated |
increases expression affects localization multiple interactions |
ISO |
Thapsigargin results in increased expression of BRCA1 mRNA; Thapsigargin results in increased expression of BRCA1 protein Thapsigargin affects the localization of BRCA1 mRNA Cycloheximide inhibits the reaction [Thapsigargin affects the localization of BRCA1 mRNA]; Emetine inhibits the reaction [Thapsigargin affects the localization of BRCA1 mRNA] |
CTD |
PMID:16434996 PMID:29576526 |
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NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
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G |
Brca2 |
BRCA2, DNA repair associated |
increases expression |
ISO |
Thapsigargin results in increased expression of BRCA2 mRNA; Thapsigargin results in increased expression of BRCA2 protein |
CTD |
PMID:16434996 |
|
NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
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G |
Brinp1 |
BMP/retinoic acid inducible neural specific 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BRINP1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 5:82,348,501...82,550,506
Ensembl chr 5:82,348,930...82,493,150
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G |
Brsk1 |
BR serine/threonine kinase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of BRSK1 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 1:69,134,166...69,159,947
Ensembl chr 1:69,134,565...69,160,365
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G |
Bub1b |
BUB1 mitotic checkpoint serine/threonine kinase B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BUB1B mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
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G |
C1qbp |
complement C1q binding protein |
decreases expression |
ISO |
Thapsigargin results in decreased expression of C1QBP mRNA |
CTD |
PMID:22378314 |
|
NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649
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G |
C5 |
complement C5 |
increases expression |
ISO |
Thapsigargin results in increased expression of C5 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
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G |
Cacna1a |
calcium voltage-gated channel subunit alpha1 A |
increases expression |
ISO |
Thapsigargin results in increased expression of CACNA1A mRNA |
CTD |
PMID:19442820 |
|
NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225
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G |
Cacna2d1 |
calcium voltage-gated channel auxiliary subunit alpha2delta 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CACNA2D1 protein |
CTD |
PMID:24648495 |
|
NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969
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G |
Cacna2d2 |
calcium voltage-gated channel auxiliary subunit alpha2delta 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CACNA2D2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 8:108,072,208...108,203,516
Ensembl chr 8:108,072,454...108,203,173
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G |
Cacng4 |
calcium voltage-gated channel auxiliary subunit gamma 4 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CACNG4 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr10:92,686,100...92,745,601
Ensembl chr10:92,683,761...92,746,126
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G |
Cadm1 |
cell adhesion molecule 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CADM1 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
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G |
Calca |
calcitonin-related polypeptide alpha |
multiple interactions |
ISO |
Thapsigargin promotes the reaction [Lipopolysaccharides results in increased expression of CALCA mRNA] |
CTD |
PMID:20682585 |
|
NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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G |
Calcb |
calcitonin-related polypeptide, beta |
increases expression |
ISO |
Thapsigargin results in increased expression of CALCB mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 1:168,966,465...168,970,125
Ensembl chr 1:168,966,465...168,970,125
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G |
Calr |
calreticulin |
increases expression |
ISO |
Thapsigargin results in increased expression of CALR mRNA; Thapsigargin results in increased expression of CALR protein |
CTD |
PMID:17353921 PMID:22378314 PMID:27587023 PMID:29453283 |
|
NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
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G |
Calu |
calumenin |
decreases expression increases expression |
ISO |
Thapsigargin results in decreased expression of CALU mRNA; Thapsigargin results in decreased expression of CALU protein Thapsigargin results in increased expression of CALU mRNA |
CTD |
PMID:21692457 PMID:22378314 |
|
NCBI chr 4:57,949,086...57,976,589
Ensembl chr 4:57,948,997...57,976,593
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G |
Camk4 |
calcium/calmodulin-dependent protein kinase IV |
multiple interactions |
EXP |
Thapsigargin inhibits the reaction [LIF protein results in increased activity of CAMK4 protein] |
CTD |
PMID:11073891 |
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NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487
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Canx |
calnexin |
increases expression affects localization |
ISO EXP |
Thapsigargin results in increased expression of CANX mRNA; Thapsigargin results in increased expression of CANX protein Thapsigargin affects the localization of CANX protein |
CTD |
PMID:17353921 PMID:22378314 PMID:28315715 PMID:28940366 PMID:29453283 |
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NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
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G |
Capn1 |
calpain 1 |
increases expression multiple interactions |
EXP |
Thapsigargin results in increased expression of CAPN1 protein Thapsigargin promotes the reaction [cadmium acetate results in increased expression of CAPN1 protein] |
CTD |
PMID:28347754 |
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NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
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G |
Car10 |
carbonic anhydrase 10 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CA10 mRNA |
CTD |
PMID:22378314 |
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NCBI chr10:78,055,875...78,556,490
Ensembl chr10:78,054,114...78,555,834
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G |
Car5b |
carbonic anhydrase 5B |
increases expression |
ISO |
Thapsigargin results in increased expression of CA5B mRNA |
CTD |
PMID:22378314 |
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NCBI chr X:30,474,697...30,534,797
Ensembl chr X:30,474,784...30,533,837
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G |
Card9 |
caspase recruitment domain family, member 9 |
increases expression |
ISO |
Thapsigargin results in increased expression of CARD9 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
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G |
Carhsp1 |
calcium regulated heat stable protein 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CARHSP1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019
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G |
Casp1 |
caspase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CASP1 mRNA |
CTD |
PMID:30796460 |
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NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp12 |
caspase 12 |
multiple interactions increases cleavage increases activity increases expression |
ISO EXP |
demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased expression of CASP12 protein modified form]; Resveratrol inhibits the reaction [Thapsigargin results in increased activity of CASP12 protein]; ursodoxicoltaurine inhibits the reaction [Thapsigargin results in increased cleavage of CASP12 protein] 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Thapsigargin results in increased expression of CASP12 protein modified form]; Apigenin inhibits the reaction [Thapsigargin results in increased activity of CASP12 protein]; O-1602 compound inhibits the reaction [Thapsigargin results in increased expression of CASP12 protein modified form]; Thapsigargin promotes the reaction [Arsenic Trioxide results in increased expression of CASP12 protein modified form] Thapsigargin results in increased cleavage of CASP12 protein alternative form |
CTD |
PMID:12198651 PMID:16338971 PMID:18477628 PMID:20493918 PMID:24224909 PMID:26264395 PMID:27638049 PMID:30841431 More...
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NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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G |
Casp2 |
caspase 2 |
multiple interactions increases activity |
ISO |
Diclofenac inhibits the reaction [Thapsigargin results in increased activity of CASP2 protein] |
CTD |
PMID:16388830 |
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NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
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G |
Casp3 |
caspase 3 |
multiple interactions increases expression increases metabolic processing increases cleavage increases activity |
ISO EXP |
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased expression of CASP3 protein]; Bortezomib promotes the reaction [Thapsigargin results in increased activity of CASP3 protein]; Cyclosporine inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]; Diclofenac inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]; Melatonin inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased activity of CASP3 protein]; ursodoxicoltaurine inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein] Thapsigargin results in increased expression of CASP3 protein; Thapsigargin results in increased expression of CASP3 protein alternative form Thapsigargin results in increased metabolism of CASP3 protein 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased expression of CASP3 protein]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Thapsigargin results in increased cleavage of CASP3 protein]; Apigenin inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]; HR protein affects the reaction [Thapsigargin results in increased activity of CASP3 protein]; O-1602 compound inhibits the reaction [Thapsigargin results in increased cleavage of CASP3 protein]; Thapsigargin promotes the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form] 1-Deoxynojirimycin inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein] |
CTD |
PMID:12198651 PMID:12871656 PMID:16338971 PMID:16357177 PMID:16382148 PMID:16388830 PMID:17559149 PMID:18178165 PMID:19028522 PMID:20022965 PMID:20130848 PMID:20493918 PMID:20886113 PMID:22800509 PMID:23576437 PMID:25341683 PMID:27638049 PMID:30841431 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp4 |
caspase 4 |
multiple interactions |
ISO |
Thapsigargin promotes the reaction [pterostilbene results in increased activity of CASP4 protein]; Thapsigargin results in increased cleavage of and results in increased activity of CASP4 protein |
CTD |
PMID:17559149 PMID:25341683 |
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NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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G |
Casp6 |
caspase 6 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CASP6 protein |
CTD |
PMID:24648495 |
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NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
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G |
Casp7 |
caspase 7 |
multiple interactions increases activity |
ISO |
Doxorubicin inhibits the reaction [Thapsigargin results in increased activity of and results in increased cleavage of CASP7 protein]; Thapsigargin results in increased activity of and results in increased cleavage of CASP7 protein; ursodoxicoltaurine inhibits the reaction [Thapsigargin results in increased activity of CASP7 protein] |
CTD |
PMID:12198651 PMID:16298333 PMID:17559149 PMID:19139269 PMID:20022965 |
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NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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G |
Casp8 |
caspase 8 |
increases activity |
ISO |
Thapsigargin results in increased activity of CASP8 protein |
CTD |
PMID:16018998 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
multiple interactions increases activity increases cleavage |
ISO |
Diclofenac inhibits the reaction [Thapsigargin results in increased activity of CASP9 protein]; Melatonin inhibits the reaction [Thapsigargin results in increased activity of CASP9 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased activity of CASP9 protein] 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Thapsigargin results in increased cleavage of CASP9 protein]; O-1602 compound inhibits the reaction [Thapsigargin results in increased cleavage of CASP9 protein] |
CTD |
PMID:16018998 PMID:16388830 PMID:20130848 PMID:25341683 PMID:30841431 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Casr |
calcium-sensing receptor |
multiple interactions |
EXP |
Thapsigargin inhibits the reaction [Spermine binds to and results in increased activity of CASR protein] |
CTD |
PMID:11071898 |
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NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811
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G |
Catsper2 |
cation channel, sperm associated 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CATSPER2 mRNA |
CTD |
PMID:19442820 |
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NCBI chr 3:108,368,654...108,389,380
Ensembl chr 3:108,368,668...108,388,050
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G |
Cbln2 |
cerebellin 2 precursor |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CBLN2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr18:79,940,412...79,948,766
Ensembl chr18:79,942,590...79,947,855
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G |
Ccdc171 |
coiled-coil domain containing 171 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CCDC171 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 5:97,919,965...98,403,853
Ensembl chr 5:97,920,002...98,282,833
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression decreases expression multiple interactions |
ISO EXP |
Thapsigargin results in increased expression of CCL2 mRNA Thapsigargin results in decreased expression of CCL2 mRNA Thapsigargin inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA]; Thapsigargin inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA] |
CTD |
PMID:8764118 PMID:18799549 PMID:18951912 PMID:20830808 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
increases expression |
EXP |
Thapsigargin results in increased expression of CCL3 mRNA; Thapsigargin results in increased expression of CCL3 protein |
CTD |
PMID:20830808 |
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NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccn1 |
cellular communication network factor 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CCN1 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
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G |
Ccna2 |
cyclin A2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CCNA2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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G |
Ccnb1 |
cyclin B1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CCNB1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccnb1ip1 |
cyclin B1 interacting protein 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CCNB1IP1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr15:24,014,905...24,031,357
Ensembl chr15:24,014,908...24,028,475
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G |
Ccnd1 |
cyclin D1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CCND1 mRNA |
CTD |
PMID:17332266 PMID:22378314 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccnf |
cyclin F |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CCNF mRNA |
CTD |
PMID:22378314 |
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NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101
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G |
Ccng2 |
cyclin G2 |
increases expression |
ISO |
Thapsigargin results in increased expression of CCNG2 mRNA |
CTD |
PMID:17332266 |
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NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
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G |
Ccnq |
cyclin Q |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CCNQ protein |
CTD |
PMID:24648495 |
|
NCBI chr10:63,646,532...63,647,695
Ensembl chr10:63,646,527...63,647,961
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G |
Ccpg1 |
cell cycle progression 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CCPG1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430
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G |
Cd44 |
CD44 molecule (Indian blood group) |
increases expression |
ISO |
Thapsigargin results in increased expression of CD44 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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G |
Cd55 |
CD55 molecule (Cromer blood group) |
increases expression |
ISO |
Thapsigargin results in increased expression of CD55 mRNA |
CTD |
PMID:24247028 |
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NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
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G |
Cd69 |
Cd69 molecule |
increases expression |
ISO |
Thapsigargin results in increased expression of CD69 mRNA |
CTD |
PMID:24247028 |
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NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
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G |
Cd70 |
Cd70 molecule |
increases expression |
ISO |
Thapsigargin results in increased expression of CD70 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 9:2,006,563...2,009,715
Ensembl chr 9:2,006,563...2,009,715
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G |
Cdc20 |
cell division cycle 20 |
multiple interactions increases expression |
ISO |
[Thapsigargin co-treated with 4-methoxycinnamate methyl ester] results in increased expression of CDC20 mRNA; [Thapsigargin co-treated with caffeic acid] results in increased expression of CDC20 mRNA; [Thapsigargin co-treated with Drugs, Chinese Herbal] results in increased expression of CDC20 mRNA Thapsigargin results in increased expression of CDC20 mRNA |
CTD |
PMID:19442820 |
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NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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G |
Cdc45 |
cell division cycle 45 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CDC45 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
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G |
Cdc5l |
cell division cycle 5-like |
increases expression |
ISO |
Thapsigargin results in increased expression of CDC5L protein |
CTD |
PMID:24648495 |
|
NCBI chr 9:15,564,949...15,603,453
Ensembl chr 9:15,564,767...15,603,450
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G |
Cdc7 |
cell division cycle 7 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CDC7 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778
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G |
Cdca2 |
cell division cycle associated 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of CDCA2 protein |
CTD |
PMID:24648495 |
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NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611
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G |
Cdca7 |
cell division cycle associated 7 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CDCA7 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353
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G |
Cdca7l |
cell division cycle associated 7 like |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CDCA7L mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 6:138,793,953...138,839,889
Ensembl chr 6:138,794,228...138,839,888
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G |
Cdh15 |
cadherin 15 |
increases expression |
ISO |
Thapsigargin results in increased expression of CDH15 mRNA |
CTD |
PMID:22378314 |
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NCBI chr19:50,903,757...50,927,151
Ensembl chr19:50,903,638...50,927,105
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G |
Cdipt |
CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CDIPT protein |
CTD |
PMID:24648495 |
|
NCBI chr 1:181,583,098...181,587,409
Ensembl chr 1:181,583,141...181,587,408
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G |
Cdk1 |
cyclin-dependent kinase 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CDK1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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G |
Cdk2 |
cyclin dependent kinase 2 |
multiple interactions increases expression decreases expression |
ISO |
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in increased expression of CDK2 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in increased expression of CDK2 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in increased expression of CDK2 mRNA] Thapsigargin results in decreased expression of CDK2 mRNA |
CTD |
PMID:19442820 PMID:22378314 |
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NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
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G |
Cdk2ap2 |
cyclin-dependent kinase 2 associated protein 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of CDK2AP2 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
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NCBI chr 1:201,391,056...201,393,137
Ensembl chr 1:201,391,466...201,393,137
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G |
Cdk5rap2 |
CDK5 regulatory subunit associated protein 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of CDK5RAP2 protein |
CTD |
PMID:24648495 |
|
NCBI chr 5:83,792,282...83,961,129
Ensembl chr 5:83,792,284...83,960,782
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G |
Cdk5rap3 |
CDK5 regulatory subunit associated protein 3 |
increases expression |
ISO |
Thapsigargin results in increased expression of CDK5RAP3 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590
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G |
Cdk7 |
cyclin-dependent kinase 7 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CDK7 protein |
CTD |
PMID:24648495 |
|
NCBI chr 2:31,840,545...31,865,447
Ensembl chr 2:31,840,558...31,865,383
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
ISO |
Thapsigargin results in increased expression of CDKN1A mRNA |
CTD |
PMID:29453283 PMID:33770205 |
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdr2 |
cerebellar degeneration-related protein 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of CDR2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:175,502,837...175,527,746
Ensembl chr 1:175,502,838...175,537,472
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
increases expression multiple interactions |
ISO |
Thapsigargin results in increased expression of CEBPB mRNA; Thapsigargin results in increased expression of CEBPB protein alternative form Thapsigargin promotes the reaction [CEBPB protein binds to NR1I2 promoter] |
CTD |
PMID:22378314 PMID:25616597 PMID:29453283 |
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NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Cebpe |
CCAAT/enhancer binding protein epsilon |
increases expression |
ISO |
Thapsigargin results in increased expression of CEBPE mRNA |
CTD |
PMID:29453283 |
|
NCBI chr15:28,169,885...28,171,283
Ensembl chr15:28,169,704...28,171,814
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G |
Cebpg |
CCAAT/enhancer binding protein gamma |
increases expression |
ISO |
Thapsigargin results in increased expression of CEBPG mRNA |
CTD |
PMID:22378314 PMID:29453283 |
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NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569
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G |
Cenpa |
centromere protein A |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CENPA mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
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G |
Cenpf |
centromere protein F |
increases expression |
ISO |
Thapsigargin results in increased expression of CENPF mRNA |
CTD |
PMID:19442820 |
|
NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
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G |
Cenpu |
centromere protein U |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CENPU mRNA |
CTD |
PMID:22378314 |
|
NCBI chr16:45,715,821...45,739,038
Ensembl chr16:45,714,294...45,738,823
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G |
Cep290 |
centrosomal protein 290 |
increases expression |
ISO |
Thapsigargin results in increased expression of CEP290 protein |
CTD |
PMID:24648495 |
|
NCBI chr 7:35,310,071...35,399,392
Ensembl chr 7:35,310,199...35,399,392
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G |
Ces5a |
carboxylesterase 5A |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CES5A protein |
CTD |
PMID:24648495 |
|
NCBI chr19:11,469,469...11,499,007
Ensembl chr19:11,469,469...11,499,006
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G |
Cetn2 |
centrin 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CETN2 protein |
CTD |
PMID:24648495 |
|
NCBI chr X:150,769,944...150,775,052
Ensembl chr X:150,769,953...150,774,919
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G |
Cftr |
CF transmembrane conductance regulator |
multiple interactions |
ISO |
Thapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Thapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium results in increased activity of CFTR protein mutant form]; Thapsigargin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Thapsigargin promotes the reaction [miglustat results in increased activity of CFTR protein mutant form] |
CTD |
PMID:18230692 |
|
NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
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G |
Cga |
glycoprotein hormones, alpha polypeptide |
increases expression |
ISO |
Thapsigargin results in increased expression of CGA mRNA |
CTD |
PMID:21694771 PMID:29453283 |
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NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
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G |
Cgn |
cingulin |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CGN mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 2:182,308,389...182,335,747
Ensembl chr 2:182,308,714...182,334,645
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G |
Cgnl1 |
cingulin-like 1 |
increases expression decreases expression |
ISO |
Thapsigargin results in increased expression of CGNL1 protein Thapsigargin results in decreased expression of CGNL1 mRNA |
CTD |
PMID:24648495 PMID:29453283 |
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NCBI chr 8:72,273,401...72,424,842
Ensembl chr 8:72,275,645...72,422,917
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G |
Chac1 |
ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CHAC1 mRNA |
CTD |
PMID:19442820 |
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NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
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G |
Chaf1a |
chromatin assembly factor 1 subunit A |
increases expression decreases expression |
ISO |
Thapsigargin results in increased expression of CHAF1A mRNA Thapsigargin results in decreased expression of CHAF1A mRNA |
CTD |
PMID:19442820 PMID:22378314 |
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NCBI chr 9:873,953...900,701
Ensembl chr 9:874,051...900,654
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G |
Chaf1b |
chromatin assembly factor 1 subunit B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CHAF1B mRNA |
CTD |
PMID:22378314 |
|
NCBI chr11:33,200,894...33,221,076
Ensembl chr11:33,200,981...33,221,070
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G |
Chchd6 |
coiled-coil-helix-coiled-coil-helix domain containing 6 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CHCHD6 protein |
CTD |
PMID:24648495 |
|
NCBI chr 4:121,803,501...122,024,209
Ensembl chr 4:121,792,717...122,024,216
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G |
Chchd7 |
coiled-coil-helix-coiled-coil-helix domain containing 7 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CHCHD7 protein |
CTD |
PMID:24648495 |
|
NCBI chr 5:16,957,081...16,969,388
Ensembl chr 5:16,957,188...16,961,184
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G |
Chd4 |
chromodomain helicase DNA binding protein 4 |
increases expression |
ISO |
Thapsigargin results in increased expression of CHD4 protein |
CTD |
PMID:24648495 |
|
NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541
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G |
Chek1 |
checkpoint kinase 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CHEK1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
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G |
Chga |
chromogranin A |
decreases expression increases expression |
ISO |
Thapsigargin results in decreased expression of CHGA mRNA Thapsigargin results in increased expression of CHGA mRNA |
CTD |
PMID:22378314 PMID:29453283 |
|
NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
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G |
Chid1 |
chitinase domain containing 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CHID1 protein |
CTD |
PMID:24648495 |
|
NCBI chr 1:196,594,357...196,629,700
Ensembl chr 1:196,587,509...196,629,606
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G |
Chpf |
chondroitin polymerizing factor |
increases expression |
ISO |
Thapsigargin results in increased expression of CHPF mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 9:76,963,178...76,967,878
Ensembl chr 9:76,963,184...76,967,878
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G |
Chpt1 |
choline phosphotransferase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CHPT1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 7:22,866,455...22,915,111
Ensembl chr 7:22,863,027...22,915,103
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G |
Chrm1 |
cholinergic receptor, muscarinic 1 |
multiple interactions |
ISO |
Thapsigargin inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium] |
CTD |
PMID:18316702 |
|
NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356
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G |
Chrna3 |
cholinergic receptor nicotinic alpha 3 subunit |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CHRNA3 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 8:55,401,981...55,415,012
Ensembl chr 8:55,401,702...55,415,165
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G |
Chrna5 |
cholinergic receptor nicotinic alpha 5 subunit |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CHRNA5 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:55,369,794...55,398,146
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G |
Chrnb4 |
cholinergic receptor nicotinic beta 4 subunit |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CHRNB4 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 8:55,418,379...55,436,967
Ensembl chr 8:55,418,313...55,437,027
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G |
Chst15 |
carbohydrate sulfotransferase 15 |
increases expression |
ISO |
Thapsigargin results in increased expression of CHST15 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:187,028,860...187,107,908
Ensembl chr 1:187,028,970...187,107,707
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G |
Cirbp |
cold inducible RNA binding protein |
increases expression |
ISO |
Thapsigargin results in increased expression of CIRBP mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818
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G |
Ckap5 |
cytoskeleton associated protein 5 |
increases expression |
ISO |
Thapsigargin results in increased expression of CKAP5 protein |
CTD |
PMID:24648495 |
|
NCBI chr 3:77,491,195...77,593,300
Ensembl chr 3:77,491,276...77,593,264
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G |
Ckb |
creatine kinase B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CKB mRNA; Thapsigargin results in decreased expression of CKB protein |
CTD |
PMID:21692457 PMID:22378314 |
|
NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
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G |
Clcc1 |
chloride channel CLIC-like 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CLCC1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 2:196,296,350...196,326,914
Ensembl chr 2:196,296,393...196,326,913
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G |
Clec11a |
C-type lectin domain containing 11A |
increases expression |
ISO |
Thapsigargin results in increased expression of CLEC11A mRNA |
CTD |
PMID:19442820 |
|
NCBI chr 1:94,800,456...94,809,002
Ensembl chr 1:94,801,496...94,804,633
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G |
Cln8 |
CLN8, transmembrane ER and ERGIC protein |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CLN8 protein |
CTD |
PMID:24648495 |
|
NCBI chr16:74,749,662...74,759,553
Ensembl chr16:74,749,662...74,759,774
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G |
Clpp |
caseinolytic mitochondrial matrix peptidase proteolytic subunit |
increases expression |
ISO |
Thapsigargin results in increased expression of CLPP mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 9:1,831,680...1,837,700
Ensembl chr 9:1,830,311...1,837,693
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G |
Cltc |
clathrin heavy chain |
increases expression |
ISO |
Thapsigargin results in increased expression of CLTC protein |
CTD |
PMID:24648495 |
|
NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
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G |
Cnn3 |
calponin 3 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CNN3 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 2:209,518,948...209,550,107
Ensembl chr 2:209,518,948...209,550,104
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G |
Cntnap2 |
contactin associated protein 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of CNTNAP2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027
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G |
Cog1 |
component of oligomeric golgi complex 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of COG1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr10:98,695,481...98,708,495
Ensembl chr10:98,695,423...98,709,292
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G |
Cog3 |
component of oligomeric golgi complex 3 |
increases expression |
ISO |
Thapsigargin results in increased expression of COG3 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr15:51,020,808...51,071,288
Ensembl chr15:51,020,813...51,070,570
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G |
Cog6 |
component of oligomeric golgi complex 6 |
increases expression |
ISO |
Thapsigargin results in increased expression of COG6 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 2:137,062,127...137,099,176
Ensembl chr 2:137,061,346...137,099,190
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|
G |
Col11a1 |
collagen type XI alpha 1 chain |
increases expression |
ISO |
Thapsigargin results in increased expression of COL11A1 protein |
CTD |
PMID:24648495 |
|
NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
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G |
Col5a1 |
collagen type V alpha 1 chain |
increases expression decreases expression |
ISO |
Thapsigargin results in increased expression of COL5A1 mRNA Thapsigargin results in decreased expression of COL5A1 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
|
NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
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G |
Col5a2 |
collagen type V alpha 2 chain |
increases expression |
ISO |
Thapsigargin results in increased expression of COL5A2 protein |
CTD |
PMID:24648495 |
|
NCBI chr 9:47,448,736...47,598,396
Ensembl chr 9:47,448,736...47,598,154
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G |
Col6a3 |
collagen type VI alpha 3 chain |
multiple interactions |
ISO |
Thapsigargin promotes the reaction [COL6A3 gene mutant form results in increased susceptibility to Rotenone] |
CTD |
PMID:18435905 |
|
NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471
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G |
Colec12 |
collectin sub-family member 12 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of COLEC12 protein |
CTD |
PMID:24648495 |
|
NCBI chr18:732,950...920,620
Ensembl chr18:732,950...920,618
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G |
Copa |
COPI coat complex subunit alpha |
increases expression |
ISO |
Thapsigargin results in increased expression of COPA mRNA |
CTD |
PMID:22378314 |
|
NCBI chr13:84,546,483...84,586,879
Ensembl chr13:84,545,943...84,586,874
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G |
Copg1 |
COPI coat complex subunit gamma 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of COPG1 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
|
NCBI chr 4:120,366,540...120,392,502
Ensembl chr 4:120,366,542...120,415,616
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G |
Cops4 |
COP9 signalosome subunit 4 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of COPS4 protein |
CTD |
PMID:21692457 |
|
NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,078,576...9,108,887
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G |
Cops7a |
COP9 signalosome subunit 7A |
decreases expression |
ISO |
Thapsigargin results in decreased expression of COPS7A protein |
CTD |
PMID:24648495 |
|
NCBI chr 4:157,766,626...157,792,632
Ensembl chr 4:157,766,588...157,773,948
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G |
Coq3 |
coenzyme Q3 methyltransferase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of COQ3 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607
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G |
Coq8a |
coenzyme Q8A |
increases expression |
ISO |
Thapsigargin results in increased expression of COQ8A mRNA |
CTD |
PMID:22378314 |
|
NCBI chr13:91,904,731...91,933,588
Ensembl chr13:91,904,739...91,931,431
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G |
Coro1a |
coronin 1A |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CORO1A mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534
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G |
Cotl1 |
coactosin-like F-actin binding protein 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of COTL1 protein |
CTD |
PMID:24648495 |
|
NCBI chr19:47,871,689...47,906,010
Ensembl chr19:47,871,694...47,911,689
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G |
Cox10 |
cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 |
increases expression |
ISO |
Thapsigargin results in increased expression of COX10 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr10:48,630,993...48,742,835
Ensembl chr10:48,630,676...48,746,667
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G |
Cox11 |
cytochrome c oxidase copper chaperone COX11 |
increases expression |
ISO |
Thapsigargin results in increased expression of COX11 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr10:75,458,735...75,465,322
Ensembl chr10:75,458,749...75,465,322
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G |
Cox17 |
cytochrome c oxidase copper chaperone COX17 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of COX17 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr11:62,400,733...62,406,507
|
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G |
Cox6b1 |
cytochrome c oxidase subunit 6B1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of COX6B1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:85,875,080...85,884,081
Ensembl chr 1:85,875,109...85,884,001
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G |
Cox6c |
cytochrome c oxidase subunit 6C |
decreases expression |
ISO |
Thapsigargin results in decreased expression of COX6C mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 7:67,129,265...67,142,001
Ensembl chr 7:67,111,024...67,141,963
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G |
Cox7b |
cytochrome c oxidase subunit 7B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of COX7B mRNA |
CTD |
PMID:22378314 |
|
NCBI chr X:71,083,486...71,089,733
Ensembl chr X:71,083,456...71,089,732
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G |
Cpne1 |
copine 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CPNE1 protein |
CTD |
PMID:21692457 |
|
NCBI chr 3:144,587,548...144,629,603
Ensembl chr 3:144,588,995...144,598,636
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G |
Cpsf1 |
cleavage and polyadenylation specific factor 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CPSF1 protein |
CTD |
PMID:24648495 |
|
NCBI chr 7:108,319,429...108,330,023
Ensembl chr 7:108,319,434...108,329,934
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G |
Cpt1c |
carnitine palmitoyltransferase 1c |
increases expression |
ISO |
Thapsigargin results in increased expression of CPT1C mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:95,442,814...95,457,347
Ensembl chr 1:95,442,817...95,457,342
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G |
Crabp1 |
cellular retinoic acid binding protein 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CRABP1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 8:55,138,363...55,159,360
Ensembl chr 8:55,151,285...55,159,360
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G |
Crabp2 |
cellular retinoic acid binding protein 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CRABP2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
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G |
Crat |
carnitine O-acetyltransferase |
increases expression |
ISO |
Thapsigargin results in increased expression of CRAT mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255
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G |
Creb1 |
cAMP responsive element binding protein 1 |
affects localization multiple interactions |
ISO |
Thapsigargin affects the localization of CREB1 mRNA Cycloheximide inhibits the reaction [Thapsigargin affects the localization of CREB1 mRNA]; Emetine inhibits the reaction [Thapsigargin affects the localization of CREB1 mRNA] |
CTD |
PMID:29576526 |
|
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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G |
Creb3l1 |
cAMP responsive element binding protein 3-like 1 |
increases activity multiple interactions |
ISO |
Thapsigargin results in increased activity of CREB3L1 protein [Thapsigargin results in increased activity of CREB3L1 protein] which results in increased expression of VEGFA mRNA |
CTD |
PMID:23383089 |
|
NCBI chr 3:77,952,589...77,993,513
Ensembl chr 3:77,952,540...77,993,456
|
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G |
Creb3l2 |
cAMP responsive element binding protein 3-like 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of CREB3L2 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
|
NCBI chr 4:65,907,570...66,112,078
Ensembl chr 4:65,907,655...66,023,763
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G |
Crebbp |
CREB binding protein |
increases expression |
ISO |
Thapsigargin results in increased expression of CREBBP mRNA |
CTD |
PMID:24247028 |
|
NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
|
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G |
Creg1 |
cellular repressor of E1A-stimulated genes 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CREG1 protein |
CTD |
PMID:24648495 |
|
NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308
|
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G |
Creld1 |
cysteine-rich with EGF-like domains 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CRELD1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 4:146,631,883...146,641,493
Ensembl chr 4:146,631,883...146,641,499
|
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G |
Creld2 |
cysteine-rich with EGF-like domains 2 |
increases expression decreases expression |
ISO |
Thapsigargin results in increased expression of CRELD2 mRNA; Thapsigargin results in increased expression of CRELD2 protein Thapsigargin results in decreased expression of CRELD2 protein |
CTD |
PMID:22378314 PMID:24648495 PMID:29453283 |
|
NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:119,909,633...119,916,543
|
|
G |
Crk |
CRK proto-oncogene, adaptor protein |
multiple interactions |
EXP |
Thapsigargin inhibits the reaction [Sincalide results in increased phosphorylation of CRK protein] |
CTD |
PMID:16187300 |
|
NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406
|
|
G |
Crtac1 |
cartilage acidic protein 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CRTAC1 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 1:241,091,679...241,233,677
Ensembl chr 1:241,078,864...241,233,421
|
|
G |
Cry1 |
cryptochrome circadian regulator 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CRY1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
|
|
G |
Crybb2 |
crystallin, beta B2 |
increases expression |
ISO |
Thapsigargin results in increased expression of CRYBB2 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr12:43,569,747...43,579,671
Ensembl chr12:43,569,747...43,579,671
|
|
G |
Crybg3 |
crystallin beta-gamma domain containing 3 |
increases expression |
ISO |
Thapsigargin results in increased expression of CRYBG3 protein |
CTD |
PMID:24648495 |
|
NCBI chr11:40,749,198...40,861,753
Ensembl chr11:40,749,214...40,861,752
|
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G |
Cryz |
crystallin zeta |
multiple interactions increases expression decreases expression |
ISO |
Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in increased expression of CRYZ mRNA] Thapsigargin results in decreased expression of CRYZ mRNA |
CTD |
PMID:19442820 PMID:22378314 |
|
NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758
|
|
G |
Cs |
citrate synthase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CS mRNA |
CTD |
PMID:28223344 |
|
NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
|
|
G |
Csnk2a2 |
casein kinase 2 alpha 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of CSNK2A2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080
|
|
G |
Cspg5 |
chondroitin sulfate proteoglycan 5 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CSPG5 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 8:110,220,653...110,234,750
Ensembl chr 8:110,220,653...110,234,758
|
|
G |
Csrnp1 |
cysteine and serine rich nuclear protein 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CSRNP1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183
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Csrp2 |
cysteine and glycine-rich protein 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CSRP2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745
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Cstf2 |
cleavage stimulation factor subunit 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CSTF2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr X:97,253,559...97,279,476
Ensembl chr X:97,253,586...97,279,476
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G |
Ctf1 |
cardiotrophin 1 |
multiple interactions |
ISO |
[Thapsigargin co-treated with 4-methoxycinnamate methyl ester] results in decreased expression of CTF1 mRNA; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of CTF1 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of CTF1 mRNA] |
CTD |
PMID:19442820 |
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NCBI chr 1:182,328,035...182,336,346
Ensembl chr 1:182,328,090...182,333,335
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G |
Cth |
cystathionine gamma-lyase |
increases expression |
ISO |
Thapsigargin results in increased expression of CTH mRNA; Thapsigargin results in increased expression of CTH protein |
CTD |
PMID:29453283 |
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NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
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G |
Ctps1 |
CTP synthase 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CTPS mRNA |
CTD |
PMID:22378314 |
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NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180
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G |
Ctr9 |
CTR9 homolog, Paf1/RNA polymerase II complex component |
increases expression |
ISO |
Thapsigargin results in increased expression of CTR9 protein |
CTD |
PMID:24648495 |
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NCBI chr 1:165,137,277...165,167,303
Ensembl chr 1:165,137,215...165,167,303
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G |
Ctsl |
cathepsin L |
multiple interactions |
ISO |
Thapsigargin inhibits the reaction [Cadmium Chloride results in increased cleavage of CTSL protein] |
CTD |
PMID:25639782 |
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NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
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G |
Ctxn1 |
cortexin 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CTXN1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr12:2,610,465...2,612,076
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
ISO |
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of CXCL2 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of CXCL2 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of CXCL2 mRNA] |
CTD |
PMID:19442820 |
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NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
increases expression |
ISO |
Thapsigargin results in increased expression of CXCL1 mRNA |
CTD |
PMID:8764118 |
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NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
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G |
Cyb561d2 |
cytochrome b561 family, member D2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CYB561D2 protein |
CTD |
PMID:24648495 |
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NCBI chr 8:108,213,201...108,215,778
Ensembl chr 8:108,213,205...108,215,759
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G |
Cyb5a |
cytochrome b5 type A |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CYB5A mRNA |
CTD |
PMID:22378314 |
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NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535 Ensembl chr18:78,202,342...78,258,535
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G |
Cyb5b |
cytochrome b5 type B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CYB5B mRNA |
CTD |
PMID:22378314 |
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NCBI chr19:35,062,871...35,096,741
Ensembl chr19:35,062,813...35,098,249
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Cyb5r1 |
cytochrome b5 reductase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CYB5R1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr13:45,849,017...45,855,458
Ensembl chr13:45,849,091...45,855,458
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G |
Cyba |
cytochrome b-245 alpha chain |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CYBA mRNA |
CTD |
PMID:29453283 |
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NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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G |
Cycs |
cytochrome c, somatic |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CYCS mRNA |
CTD |
PMID:22378314 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
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G |
Cyfip1 |
cytoplasmic FMR1 interacting protein 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CYFIP1 protein |
CTD |
PMID:24648495 |
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NCBI chr 1:106,710,924...106,799,393
Ensembl chr 1:106,711,016...106,799,386
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G |
Cygb |
cytoglobin |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CYGB mRNA |
CTD |
PMID:22378314 |
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NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CYP1B1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
multiple interactions |
ISO |
NR1I2 protein inhibits the reaction [Thapsigargin inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; Thapsigargin inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA] |
CTD |
PMID:25616597 |
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NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
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G |
Cyp4f18 |
cytochrome P450, family 4, subfamily f, polypeptide 18 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CYP4F3 mRNA |
CTD |
PMID:19442820 |
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NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940
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G |
Cyp4v3 |
cytochrome P450, family 4, subfamily v, polypeptide 3 |
increases expression |
ISO |
Thapsigargin results in increased expression of CYP4V2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr16:46,917,929...46,958,735
Ensembl chr16:46,918,401...46,943,395
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G |
Cyp4x1 |
cytochrome P450, family 4, subfamily x, polypeptide 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CYP4X1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 5:128,652,844...128,683,338
Ensembl chr 5:128,651,776...128,682,779
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G |
Dap |
death-associated protein |
multiple interactions increases expression |
ISO |
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of DAP mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of DAP mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of DAP mRNA] Thapsigargin results in increased expression of DAP mRNA |
CTD |
PMID:19442820 PMID:22378314 |
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NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:82,199,280...82,251,752
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G |
Dbi |
diazepam binding inhibitor |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DBI mRNA |
CTD |
PMID:22378314 |
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NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
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G |
Dbnl |
drebrin-like |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DBNL mRNA |
CTD |
PMID:22378314 |
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NCBI chr14:80,666,115...80,681,155
Ensembl chr14:80,666,124...80,681,155
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G |
Dctpp1 |
dCTP pyrophosphatase 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DCTPP1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:181,877,440...181,880,833
Ensembl chr 1:181,877,437...181,880,839
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G |
Ddah1 |
dimethylarginine dimethylaminohydrolase 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DDAH1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
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G |
Ddb1 |
damage-specific DNA binding protein 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of DDB1 protein |
CTD |
PMID:24648495 |
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NCBI chr 1:207,252,890...207,278,685
Ensembl chr 1:207,252,890...207,278,676
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G |
Ddc |
dopa decarboxylase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DDC mRNA |
CTD |
PMID:22378314 |
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NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
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G |
Ddias |
DNA damage-induced apoptosis suppressor |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DDIAS mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:146,906,150...146,930,462
Ensembl chr 1:146,906,154...146,930,462
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions decreases response to substance increases activity increases expression |
ISO EXP |
ATF6 promotes the reaction [Thapsigargin results in increased expression of DDIT3 protein]; demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Doxorubicin inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; EIF2AK3 promotes the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Luteolin inhibits the reaction [Thapsigargin results in increased expression of DDIT3 mRNA]; Luteolin inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Quercetin inhibits the reaction [Thapsigargin results in increased expression of DDIT3 mRNA]; Thapsigargin promotes the reaction [DDIT3 protein binds to LCN2 promoter]; Thapsigargin promotes the reaction [pterostilbene results in increased expression of DDIT3 protein]; Thapsigargin results in increased expression of and affects the localization of DDIT3 protein DDIT3 results in decreased susceptibility to Thapsigargin 2-aminoethoxydiphenyl borate inhibits the reaction [Thapsigargin results in increased expression of DDIT3 mRNA]; 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Apigenin inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of DDIT3 mRNA]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Glutathione inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Luteolin inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; PTPN1 gene mutant form promotes the reaction [Thapsigargin results in increased expression of DDIT3 mRNA]; PTPN1 gene mutant form promotes the reaction [Thapsigargin results in increased expression of DDIT3 protein]; salubrinal inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Thapsigargin inhibits the reaction [7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased expression of DDIT3 protein]]; Thapsigargin promotes the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; Vaticanol B inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein] Thapsigargin results in increased activity of DDIT3 protein 1-Deoxynojirimycin inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; GW 506033X inhibits the reaction [Thapsigargin results in increased expression of DDIT3 mRNA]; salubrinal promotes the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Thapsigargin results in increased expression of and affects the localization of DDIT3 protein Thapsigargin results in increased expression of DDIT3 mRNA; Thapsigargin results in increased expression of DDIT3 protein |
CTD |
PMID:16298333 PMID:16330322 PMID:16338971 PMID:17283163 PMID:17332266 PMID:17353921 PMID:17475668 PMID:19028522 PMID:19135031 PMID:19139269 PMID:19285962 PMID:19428936 PMID:20022965 PMID:20493918 PMID:20589738 PMID:20626587 PMID:21525004 PMID:21694771 PMID:22378314 PMID:22509299 PMID:22641616 PMID:22800509 PMID:22843330 PMID:22935518 PMID:24648495 PMID:24668805 PMID:24865413 PMID:25289770 PMID:25324550 PMID:25341683 PMID:25611565 PMID:26264395 PMID:26513129 PMID:27226639 PMID:27358234 PMID:27587023 PMID:27638049 PMID:28223344 PMID:28315715 PMID:28844859 PMID:28940366 PMID:28942281 PMID:29109149 PMID:29414781 PMID:29453283 PMID:30508555 PMID:32407927 PMID:32535746 PMID:32574669 PMID:32578922 PMID:34915026 PMID:35033536 More...
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddost |
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit |
increases expression |
ISO |
Thapsigargin results in increased expression of DDOST mRNA |
CTD |
PMID:22378314 |
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NCBI chr 5:150,522,297...150,529,413
Ensembl chr 5:150,522,242...150,529,413
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G |
Ddr2 |
discoidin domain receptor tyrosine kinase 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of DDR2 protein |
CTD |
PMID:24648495 |
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NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
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G |
Ddrgk1 |
DDRGK domain containing 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of DDRGK1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680
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G |
Dennd4c |
DENN domain containing 4C |
increases expression |
ISO |
Thapsigargin results in increased expression of DENND4C protein |
CTD |
PMID:24648495 |
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NCBI chr 5:101,272,298...101,369,529
Ensembl chr 5:101,272,005...101,368,118
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G |
Depdc1b |
DEP domain containing 1B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DEPDC1B mRNA |
CTD |
PMID:22378314 |
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NCBI chr 2:39,891,163...39,963,779
Ensembl chr 2:39,891,481...39,963,779
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G |
Deptor |
DEP domain containing MTOR-interacting protein |
increases expression |
ISO |
Thapsigargin results in increased expression of DEPTOR mRNA |
CTD |
PMID:22378314 |
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NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773
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G |
Derl2 |
derlin 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of DERL2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr10:55,727,764...55,739,462
Ensembl chr10:55,727,643...55,739,518
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G |
Dglucy |
D-glutamate cyclase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DGLUCY mRNA |
CTD |
PMID:22378314 |
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NCBI chr 6:120,055,480...120,130,910
Ensembl chr 6:120,055,460...120,130,910
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G |
Dhcr24 |
24-dehydrocholesterol reductase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DHCR24 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137
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G |
Dhcr7 |
7-dehydrocholesterol reductase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DHCR7 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
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G |
Dhrs13 |
dehydrogenase/reductase 13 |
increases expression |
ISO |
Thapsigargin results in increased expression of DHRS13 mRNA |
CTD |
PMID:29453283 |
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NCBI chr10:62,920,743...62,925,952
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G |
Dhrs3 |
dehydrogenase/reductase 3 |
increases expression |
ISO |
Thapsigargin results in increased expression of DHRS3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
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G |
Dhx36 |
DEAH-box helicase 36 |
increases expression |
ISO |
Thapsigargin results in increased expression of DHX36 protein |
CTD |
PMID:24648495 |
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NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572
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G |
Dhx9 |
DExH-box helicase 9 |
increases expression |
ISO |
Thapsigargin results in increased expression of DHX9 protein |
CTD |
PMID:24648495 |
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NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
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G |
Diablo |
diablo, IAP-binding mitochondrial protein |
affects response to substance affects localization increases expression |
ISO |
DIABLO protein affects the susceptibility to Thapsigargin Thapsigargin affects the localization of DIABLO protein Thapsigargin results in increased expression of DIABLO mRNA |
CTD |
PMID:15339911 PMID:16382148 PMID:22378314 |
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NCBI chr12:33,055,784...33,070,400
Ensembl chr12:33,055,263...33,070,387
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G |
Diaph2 |
diaphanous-related formin 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of DIAP2 protein |
CTD |
PMID:24648495 |
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NCBI chr X:92,395,189...93,234,521
Ensembl chr X:92,395,251...93,229,869
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G |
Diaph3 |
diaphanous-related formin 3 |
increases expression |
ISO |
Thapsigargin results in increased expression of DIAPH3 protein |
CTD |
PMID:24648495 |
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NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975
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G |
Dkk1 |
dickkopf WNT signaling pathway inhibitor 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DKK1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
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G |
Dld |
dihydrolipoamide dehydrogenase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DLD mRNA |
CTD |
PMID:22378314 |
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NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
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G |
Dlg4 |
discs large MAGUK scaffold protein 4 |
increases expression |
ISO |
Thapsigargin results in increased expression of DLG4 mRNA |
CTD |
PMID:22378314 |
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NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
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G |
Dlgap5 |
DLG associated protein 5 |
decreases expression increases expression |
ISO |
Thapsigargin results in decreased expression of DLGAP5 mRNA Thapsigargin results in increased expression of DLGAP5 protein |
CTD |
PMID:22378314 PMID:24648495 |
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NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
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G |
Dlk1 |
delta like non-canonical Notch ligand 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DLK1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522
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G |
Dlx5 |
distal-less homeobox 5 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DLX5 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 4:34,999,139...35,003,504
Ensembl chr 4:34,999,139...35,003,407
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G |
Dmac2l |
distal membrane arm assembly component 2 like |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DMAC2L mRNA |
CTD |
PMID:22378314 |
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NCBI chr 6:88,205,580...88,223,934
Ensembl chr 6:88,205,700...88,223,933
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G |
Dnaja1 |
DnaJ heat shock protein family (Hsp40) member A1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DNAJA1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
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G |
Dnaja3 |
DnaJ heat shock protein family (Hsp40) member A3 |
increases expression |
ISO |
Thapsigargin results in increased expression of DNAJA3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr10:10,855,510...10,880,175
Ensembl chr10:10,854,732...10,880,161
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G |
Dnajb11 |
DnaJ heat shock protein family (Hsp40) member B11 |
multiple interactions decreases expression increases expression |
ISO |
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of DNAJB11 mRNA]; [DNAJB11 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of DNAJB11 mRNA] Thapsigargin results in increased expression of DNAJB11 mRNA; Thapsigargin results in increased expression of DNAJB11 protein |
CTD |
PMID:19442820 PMID:22378314 PMID:26085089 PMID:29453283 |
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NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407
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G |
Dnajb9 |
DnaJ heat shock protein family (Hsp40) member B9 |
increases expression |
ISO |
Thapsigargin results in increased expression of DNAJB9 mRNA |
CTD |
PMID:19135031 PMID:22378314 PMID:29453283 |
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NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
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G |
Dnajc1 |
DnaJ heat shock protein family (Hsp40) member C1 |
affects expression |
ISO |
Thapsigargin affects the expression of DNAJC1 mRNA |
CTD |
PMID:24247028 |
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NCBI chr17:80,955,209...81,112,025
Ensembl chr17:80,955,237...81,111,988
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G |
Dnajc10 |
DnaJ heat shock protein family (Hsp40) member C10 |
increases expression |
ISO |
Thapsigargin results in increased expression of DNAJC10 mRNA; Thapsigargin results in increased expression of DNAJC10 protein |
CTD |
PMID:17353921 PMID:29453283 |
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NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
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G |
Dnajc3 |
DnaJ heat shock protein family (Hsp40) member C3 |
increases expression multiple interactions |
ISO |
Thapsigargin results in increased expression of DNAJC3 mRNA; Thapsigargin results in increased expression of DNAJC3 protein [DNAJC3 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin |
CTD |
PMID:19135031 PMID:26085089 PMID:29453283 |
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NCBI chr15:96,025,729...96,065,114
Ensembl chr15:96,025,624...96,065,181
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G |
Dnase2 |
deoxyribonuclease 2, lysosomal |
increases expression |
ISO |
Thapsigargin results in increased expression of DNASE2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr19:23,244,661...23,247,329
Ensembl chr19:23,244,664...23,247,376
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G |
Dnhd1 |
dynein heavy chain domain 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of DNHD1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:159,990,785...160,077,990
Ensembl chr 1:159,990,438...160,074,858
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G |
Dnm1l |
dynamin 1-like |
increases expression |
ISO |
Thapsigargin results in increased expression of DNM1L mRNA |
CTD |
PMID:28940366 |
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NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
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G |
Dnmt1 |
DNA methyltransferase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of DNMT1 protein |
CTD |
PMID:24648495 |
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NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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G |
Dock7 |
dedicator of cytokinesis 7 |
increases expression |
ISO |
Thapsigargin results in increased expression of DOCK7 protein |
CTD |
PMID:24648495 |
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NCBI chr 5:113,599,371...113,782,871
Ensembl chr 5:113,600,198...113,782,813
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G |
Dpf1 |
double PHD fingers 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DPF1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:84,602,212...84,615,954
Ensembl chr 1:84,602,336...84,615,950
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G |
Dph5 |
diphthamide biosynthesis 5 |
increases expression |
ISO |
Thapsigargin results in increased expression of DPH5 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 2:203,804,620...203,858,196
Ensembl chr 2:203,804,936...203,840,433
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G |
Dpysl3 |
dihydropyrimidinase-like 3 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DPYSL3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr18:35,374,429...35,480,462
Ensembl chr18:35,377,181...35,480,157
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G |
Dpysl4 |
dihydropyrimidinase-like 4 |
multiple interactions increases expression |
ISO |
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in increased expression of DPYSL4 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in increased expression of DPYSL4 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in increased expression of DPYSL4 mRNA] |
CTD |
PMID:19442820 |
|
NCBI chr 1:193,883,039...193,898,916
Ensembl chr 1:193,883,106...193,898,914
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G |
Dscc1 |
DNA replication and sister chromatid cohesion 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DSCC1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212
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G |
Dse |
dermatan sulfate epimerase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DSE protein |
CTD |
PMID:24648495 |
|
NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992
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G |
Dtl |
denticleless E3 ubiquitin protein ligase homolog |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DTL mRNA |
CTD |
PMID:22378314 |
|
NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890
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G |
Dtna |
dystrobrevin, alpha |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DTNA mRNA |
CTD |
PMID:22378314 |
|
NCBI chr18:14,687,193...14,944,232
Ensembl chr18:14,587,852...14,944,261
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G |
Dusp1 |
dual specificity phosphatase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of DUSP1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr10:16,680,489...16,683,276
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G |
Dusp26 |
dual specificity phosphatase 26 |
increases expression |
ISO |
Thapsigargin results in increased expression of DUSP26 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr16:61,041,784...61,049,319
Ensembl chr16:61,041,792...61,049,051
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G |
Dusp5 |
dual specificity phosphatase 5 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DUSP5 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
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G |
Dusp6 |
dual specificity phosphatase 6 |
increases expression decreases expression |
ISO |
Thapsigargin results in increased expression of DUSP6 mRNA Thapsigargin results in decreased expression of DUSP6 mRNA |
CTD |
PMID:22378314 PMID:24247028 |
|
NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
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G |
Dut |
deoxyuridine triphosphatase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DUT mRNA Thapsigargin results in decreased expression of DUT protein |
CTD |
PMID:22378314 PMID:24648495 |
|
NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
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G |
Dym |
dymeclin |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DYM protein |
CTD |
PMID:24648495 |
|
NCBI chr18:68,605,131...68,900,905
Ensembl chr18:68,605,185...68,900,903
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G |
Dync1i1 |
dynein cytoplasmic 1 intermediate chain 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DYNC1I1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 4:33,852,597...34,166,159
Ensembl chr 4:33,852,927...34,166,149
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G |
Dync2i2 |
dynein 2 intermediate chain 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DYNC2I2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 3:13,306,039...13,322,121
Ensembl chr 3:13,306,039...13,322,121
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G |
Dyrk4 |
dual specificity tyrosine phosphorylation regulated kinase 4 |
increases expression |
ISO |
Thapsigargin results in increased expression of DYRK4 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 4:159,715,658...159,757,660
Ensembl chr 4:159,715,417...159,757,627
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G |
E2f1 |
E2F transcription factor 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of E2F1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
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G |
E2f2 |
E2F transcription factor 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of E2F2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217
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G |
E2f7 |
E2F transcription factor 7 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of E2F7 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734
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G |
Ears2 |
glutamyl-tRNA synthetase 2, mitochondrial |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EARS2 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 1:176,597,986...176,625,848
Ensembl chr 1:176,597,986...176,625,836
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G |
Ebf1 |
EBF transcription factor 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EBF1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr10:29,095,858...29,489,142
Ensembl chr10:29,099,933...29,487,665
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G |
Ech1 |
enoyl-CoA hydratase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ECH1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
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G |
Edc4 |
enhancer of mRNA decapping 4 |
increases expression |
ISO |
Thapsigargin results in increased expression of EDC4 protein |
CTD |
PMID:24648495 |
|
NCBI chr19:33,774,062...33,786,054
Ensembl chr19:33,774,055...33,787,758
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G |
Edem1 |
ER degradation enhancing alpha-mannosidase like protein 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of EDEM1 mRNA |
CTD |
PMID:22378314 PMID:27587023 |
|
NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
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G |
Eef1akmt1 |
EEF1A lysine methyltransferase 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EEF1AKMT1 protein |
CTD |
PMID:24648495 |
|
NCBI chr15:31,694,289...31,711,959
Ensembl chr15:31,694,292...31,711,336
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G |
Eepd1 |
endonuclease/exonuclease/phosphatase family domain containing 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EEPD1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 8:23,957,258...24,064,343
Ensembl chr 8:23,957,255...24,064,340
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G |
Efr3a |
EFR3 homolog A |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EFR3A protein |
CTD |
PMID:24648495 |
|
NCBI chr 7:97,552,677...97,633,369
Ensembl chr 7:97,552,677...97,633,369
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G |
Egf |
epidermal growth factor |
multiple interactions |
ISO |
Thapsigargin inhibits the reaction [EGF protein affects the localization of PRKCB protein] |
CTD |
PMID:17991733 |
|
NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
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G |
Egfr |
epidermal growth factor receptor |
increases expression |
ISO |
Thapsigargin results in increased expression of EGFR protein |
CTD |
PMID:24648495 |
|
NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Egr1 |
early growth response 1 |
increases expression decreases expression |
ISO |
Thapsigargin results in increased expression of EGR1 mRNA Thapsigargin results in decreased expression of EGR1 mRNA |
CTD |
PMID:8764118 PMID:21694771 PMID:22378314 |
|
NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
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G |
Egr2 |
early growth response 2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of EGR2 mRNA |
CTD |
PMID:20830808 |
|
NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
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G |
Eif1 |
eukaryotic translation initiation factor 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of EIF1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327
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G |
Eif2a |
eukaryotic translation initiation factor 2A |
multiple interactions increases phosphorylation increases expression |
ISO EXP |
Doxorubicin promotes the reaction [Thapsigargin results in increased phosphorylation of EIF2A protein] Thapsigargin promotes the reaction [EIF2AK3 protein results in increased phosphorylation of EIF2A protein] Thapsigargin results in increased expression of EIF2A mRNA |
CTD |
PMID:12606582 PMID:16298333 PMID:17283163 PMID:17353921 PMID:19285962 PMID:19428936 PMID:20589738 PMID:22378314 More...
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NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
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G |
Eif2ak2 |
eukaryotic translation initiation factor 2-alpha kinase 2 |
increases phosphorylation multiple interactions |
ISO |
Thapsigargin results in increased phosphorylation of EIF2AK2 protein imoxin inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2AK2 protein] |
CTD |
PMID:24150608 |
|
NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions increases response to substance increases phosphorylation increases expression increases acetylation |
ISO EXP |
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2AK3 protein]; demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2AK3 protein]; EIF2AK3 mutant form inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein]; EIF2AK3 promotes the reaction [Thapsigargin results in increased expression of DDIT3 protein]; EIF2AK3 promotes the reaction [Thapsigargin results in increased expression of HSPA5 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein] EIF2AK3 gene mutant form results in increased susceptibility to Thapsigargin 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2AK3 protein]; [Thapsigargin co-treated with HRAS protein] results in increased expression of EIF2AK3 protein; EIF2AK3 gene mutant form inhibits the reaction [Thapsigargin results in increased expression of IBTK mRNA alternative form]; PTPN1 gene mutant form promotes the reaction [Thapsigargin results in increased activity of and results in increased phosphorylation of EIF2AK3 protein]; Thapsigargin promotes the reaction [EIF2AK3 protein results in increased phosphorylation of EIF2A protein]; Thapsigargin results in increased activity of and results in increased phosphorylation of EIF2AK3 protein EIF2AK3 gene mutant form inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein] Thapsigargin results in increased expression of EIF2AK3 mRNA; Thapsigargin results in increased expression of EIF2AK3 protein; Thapsigargin results in increased expression of EIF2AK3 protein modified form Thapsigargin results in increased acetylation of EIF2AK3 protein |
CTD |
PMID:16324875 PMID:17283163 PMID:17963750 PMID:20022965 PMID:22378314 PMID:22509299 PMID:23576437 PMID:24150608 PMID:24224909 PMID:24648495 PMID:24865413 PMID:24898257 PMID:25341683 PMID:26264395 PMID:27358234 PMID:29653943 PMID:30796460 More...
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NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
multiple interactions increases phosphorylation decreases response to substance increases expression decreases phosphorylation |
ISO EXP |
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein]; EIF2AK3 mutant form inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein]; Luteolin inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein] EIF2AK3 gene mutant form inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein]; salubrinal inhibits the reaction [Thapsigargin results in increased expression of EIF2S1 mRNA] EIF2S1 protein mutant form results in decreased susceptibility to Thapsigargin Thapsigargin results in increased expression of EIF2S1 protein modified form 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of ATF4 mRNA]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of DDIT3 mRNA]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of DDIT3 protein]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of PPP1R15A mRNA]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of PPP1R15A protein]; EIF2S1 protein mutant form inhibits the reaction [Thapsigargin results in decreased expression of TIMM17A protein]; EIF2S1 protein mutant form inhibits the reaction [Thapsigargin results in increased expression of IBTK mRNA alternative form]; PTPN1 gene mutant form promotes the reaction [Thapsigargin results in increased activity of and results in increased phosphorylation of EIF2S1 protein]; Thapsigargin inhibits the reaction [7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of EIF2S1 protein]]; Thapsigargin results in increased activity of and results in increased phosphorylation of EIF2S1 protein Thapsigargin results in decreased phosphorylation of EIF2S1 protein |
CTD |
PMID:16324875 PMID:17553788 PMID:19233273 PMID:20022965 PMID:22509299 PMID:23576437 PMID:23690448 PMID:24150608 PMID:24224909 PMID:24315374 PMID:24648495 PMID:27587023 PMID:28844859 PMID:29109149 PMID:29414781 PMID:30508555 PMID:32357311 PMID:32407927 PMID:32578922 More...
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NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
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G |
Eif2s2 |
eukaryotic translation initiation factor 2 subunit beta |
affects expression increases expression |
ISO |
Thapsigargin affects the expression of EIF2S2 mRNA Thapsigargin results in increased expression of EIF2S2 mRNA |
CTD |
PMID:22378314 PMID:24247028 |
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NCBI chr 3:143,374,652...143,395,460
Ensembl chr 3:143,373,686...143,395,432
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G |
Eif3a |
eukaryotic translation initiation factor 3, subunit A |
increases expression |
ISO |
Thapsigargin results in increased expression of EIF3A protein |
CTD |
PMID:24648495 |
|
NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976
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G |
Eif3i |
eukaryotic translation initiation factor 3, subunit I |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EIF3I protein |
CTD |
PMID:21692457 |
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NCBI chr 5:141,935,135...141,942,589
Ensembl chr 5:141,935,044...141,942,676
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G |
Eif4e |
eukaryotic translation initiation factor 4E |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EIF4E mRNA; Thapsigargin results in decreased expression of EIF4E protein |
CTD |
PMID:24648495 |
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NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of EIF4EBP1 mRNA; Thapsigargin results in increased expression of EIF4EBP1 protein |
CTD |
PMID:29453283 |
|
NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
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G |
Eif5a |
eukaryotic translation initiation factor 5A |
affects response to substance |
ISO |
EIF5A protein affects the susceptibility to Thapsigargin |
CTD |
PMID:20376341 |
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NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
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G |
Eif5b |
eukaryotic translation initiation factor 5B |
increases expression |
ISO |
Thapsigargin results in increased expression of EIF5B protein |
CTD |
PMID:24648495 |
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NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482
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G |
Elf1 |
E74 like ETS transcription factor 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ELF1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr15:54,890,644...54,986,721
Ensembl chr15:54,865,616...54,986,699
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G |
Elf3 |
E74 like ETS transcription factor 3 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ELF3 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481
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G |
Elmo2 |
engulfment and cell motility 2 |
multiple interactions |
ISO |
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of ELMO2 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of ELMO2 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of ELMO2 mRNA] |
CTD |
PMID:19442820 |
|
NCBI chr 3:154,023,661...154,061,259
Ensembl chr 3:154,023,661...154,061,185
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G |
Elovl2 |
ELOVL fatty acid elongase 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ELOVL2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr17:23,544,520...23,584,855
Ensembl chr17:23,544,568...23,584,848
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G |
Emc4 |
ER membrane protein complex subunit 4 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EMC4 protein |
CTD |
PMID:24648495 |
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NCBI chr 3:99,169,711...99,174,730
Ensembl chr 3:99,169,711...99,174,729
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G |
Emilin2 |
elastin microfibril interfacer 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of EMILIN2 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 9:111,160,708...111,220,463
Ensembl chr 9:111,160,712...111,220,352
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G |
Eml2 |
EMAP like 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of EML2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:78,827,595...78,859,343
Ensembl chr 1:78,828,080...78,859,341
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G |
Enc1 |
ectodermal-neural cortex 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ENC1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
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G |
Endog |
endonuclease G |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ENDOG mRNA |
CTD |
PMID:22378314 |
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NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932
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G |
Enkd1 |
enkurin domain containing 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ENKD1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr19:33,592,074...33,596,552
Ensembl chr19:33,592,078...33,596,545
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G |
Eno2 |
enolase 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of ENO2 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
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G |
Eno3 |
enolase 3 |
increases expression |
ISO |
Thapsigargin results in increased expression of ENO3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921
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G |
Enpp2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
decreases expression increases expression |
ISO |
Thapsigargin results in decreased expression of ENPP2 mRNA Thapsigargin results in increased expression of ENPP2 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
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NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
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G |
Entpd5 |
ectonucleoside triphosphate diphosphohydrolase 5 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ENTPD5 protein |
CTD |
PMID:24648495 |
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NCBI chr 6:104,019,095...104,055,311
Ensembl chr 6:104,019,185...104,055,530
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G |
Ep400 |
E1A binding protein p400 |
increases expression |
ISO |
Thapsigargin results in increased expression of EP400 protein |
CTD |
PMID:24648495 |
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NCBI chr12:45,891,886...46,002,523
Ensembl chr12:45,891,916...45,998,861
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G |
Epas1 |
endothelial PAS domain protein 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EPAS1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228
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G |
Ephx4 |
epoxide hydrolase 4 |
increases expression |
ISO |
Thapsigargin results in increased expression of EPHX4 mRNA |
CTD |
PMID:29453283 |
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NCBI chr14:2,343,376...2,372,680
Ensembl chr14:2,340,248...2,373,022
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G |
Eprs |
glutamyl-prolyl-tRNA synthetase |
increases expression |
ISO |
Thapsigargin results in increased expression of EPRS1 mRNA Thapsigargin results in increased expression of EPRS protein |
CTD |
PMID:22378314 PMID:24648495 |
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NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966
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G |
Ercc6l |
ERCC excision repair 6 like, spindle assembly checkpoint helicase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ERCC6L mRNA |
CTD |
PMID:22378314 |
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NCBI chr X:67,245,414...67,261,222
Ensembl chr X:67,245,414...67,280,756
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G |
Erf |
Ets2 repressor factor |
multiple interactions increases expression |
ISO |
caffeic acid promotes the reaction [Thapsigargin results in increased expression of ERF mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in increased expression of ERF mRNA] |
CTD |
PMID:19442820 |
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NCBI chr 1:80,829,935...80,838,388
Ensembl chr 1:80,829,935...80,838,388
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions increases phosphorylation increases expression affects splicing |
ISO EXP |
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein]; [Thapsigargin co-treated with HRAS protein] results in increased expression of ERN1 protein; Apigenin inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein]; Thapsigargin inhibits the reaction [7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein]] 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein]; 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of ERN1 protein]; [Thapsigargin affects the splicing of ERN1 mRNA] which results in increased expression of ERN1 protein alternative form; BCL2L1 protein inhibits the reaction [Thapsigargin results in increased expression of ERN1 protein]; demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein]; EUK-134 inhibits the reaction [Thapsigargin results in increased expression of ERN1 protein]; Luteolin inhibits the reaction [Thapsigargin results in increased expression of and results in increased phosphorylation of ERN1 protein]; Thapsigargin results in increased expression of and results in increased phosphorylation of ERN1 protein Thapsigargin results in increased expression of ERN1 mRNA; Thapsigargin results in increased expression of ERN1 protein; Thapsigargin results in increased expression of ERN1 protein modified form |
CTD |
PMID:17963750 PMID:19139269 PMID:20493918 PMID:22378314 PMID:23576437 PMID:23885834 PMID:24224909 PMID:24638036 PMID:24898257 PMID:26264395 PMID:27587023 PMID:29414781 PMID:30796460 PMID:32407927 PMID:32535746 PMID:35033536 More...
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NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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G |
Ero1a |
endoplasmic reticulum oxidoreductase 1 alpha |
increases expression |
EXP |
Thapsigargin results in increased expression of ERO1A protein |
CTD |
PMID:28315715 |
|
NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
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G |
Ero1b |
endoplasmic reticulum oxidoreductase 1 beta |
increases expression |
ISO |
Thapsigargin results in increased expression of ERO1B mRNA |
CTD |
PMID:22378314 |
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NCBI chr17:85,861,086...86,003,244
Ensembl chr17:85,929,618...86,003,398
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G |
Erp44 |
endoplasmic reticulum protein 44 |
increases expression |
ISO |
Thapsigargin results in increased expression of ERP44 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 5:62,516,550...62,610,762
Ensembl chr 5:62,516,551...62,610,761
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G |
Esf1 |
ESF1 nucleolar pre-rRNA processing protein homolog |
increases expression |
ISO |
Thapsigargin results in increased expression of ESF1 protein |
CTD |
PMID:24648495 |
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NCBI chr 3:127,454,744...127,507,941
Ensembl chr 3:127,454,811...127,507,817
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G |
Esrrg |
estrogen-related receptor gamma |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ESRRG mRNA |
CTD |
PMID:22378314 |
|
NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397
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G |
Ethe1 |
ETHE1, persulfide dioxygenase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ETHE1 protein |
CTD |
PMID:24648495 |
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NCBI chr 1:80,184,037...80,199,092
Ensembl chr 1:80,183,894...80,199,052
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G |
Etv4 |
ETS variant transcription factor 4 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ETV4 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974
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G |
Etv5 |
ETS variant transcription factor 5 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ETV5 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr11:78,608,618...78,666,221
Ensembl chr11:78,608,710...78,666,215
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G |
Evi2a |
ecotropic viral integration site 2A |
increases expression |
ISO |
Thapsigargin results in increased expression of EVI2A mRNA |
CTD |
PMID:24247028 |
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NCBI chr10:64,485,760...64,489,660
Ensembl chr10:64,485,200...64,489,843
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G |
Exo1 |
exonuclease 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EXO1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654
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G |
Exoc4 |
exocyst complex component 4 |
increases expression |
ISO |
Thapsigargin results in increased expression of EXOC4 protein |
CTD |
PMID:24648495 |
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NCBI chr 4:61,807,706...62,584,316
Ensembl chr 4:61,807,761...62,585,723
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G |
Exosc2 |
exosome component 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EXOSC2 mRNA |
CTD |
PMID:24247028 |
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NCBI chr 3:14,962,930...14,973,645
Ensembl chr 3:14,962,917...14,973,575
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G |
Exosc7 |
exosome component 7 |
affects expression |
ISO |
Thapsigargin affects the expression of EXOSC7 mRNA |
CTD |
PMID:24247028 |
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NCBI chr 8:122,773,607...122,798,943
Ensembl chr 8:122,773,591...122,799,270
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G |
Ext2 |
exostosin glycosyltransferase 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EXT2 protein |
CTD |
PMID:24648495 |
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NCBI chr 3:79,665,415...79,798,077
Ensembl chr 3:79,665,415...79,798,059
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G |
Eya1 |
EYA transcriptional coactivator and phosphatase 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EYA1 protein |
CTD |
PMID:24648495 |
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NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483
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G |
F2rl1 |
F2R like trypsin receptor 1 |
decreases expression increases expression |
ISO |
Thapsigargin results in decreased expression of F2RL1 protein Thapsigargin results in increased expression of F2RL1 mRNA |
CTD |
PMID:24648495 PMID:29453283 |
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NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
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G |
Fads1 |
fatty acid desaturase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of FADS1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
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G |
Fads3 |
fatty acid desaturase 3 |
increases expression |
ISO |
Thapsigargin results in increased expression of FADS3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:206,685,667...206,702,538
Ensembl chr 1:206,685,894...206,704,769
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G |
Fam107b |
family with sequence similarity 107, member B |
increases expression decreases expression |
ISO |
Thapsigargin results in increased expression of FAM107B mRNA Thapsigargin results in decreased expression of FAM107B protein |
CTD |
PMID:22378314 PMID:24648495 |
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NCBI chr17:74,478,608...74,685,027
Ensembl chr17:74,478,608...74,684,989
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G |
Fam118b |
family with sequence similarity 118, member B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FAM118B protein |
CTD |
PMID:24648495 |
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NCBI chr 8:33,566,681...33,617,310
Ensembl chr 8:33,566,669...33,617,270
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G |
Fam120a |
family with sequence similarity 120A |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FAM120A protein |
CTD |
PMID:24648495 |
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NCBI chr17:15,684,233...15,774,964
Ensembl chr17:15,684,233...15,774,964
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G |
FAM120C |
family with sequence similarity 120C |
increases expression |
ISO |
Thapsigargin results in increased expression of FAM120C protein |
CTD |
PMID:24648495 |
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NCBI chr X:20,324,046...20,477,831
Ensembl chr X:20,323,381...20,477,275
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G |
Fam13b |
family with sequence similarity 13, member B |
increases expression |
ISO |
Thapsigargin results in increased expression of FAM13B mRNA |
CTD |
PMID:29453283 |
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NCBI chr18:26,040,285...26,107,112
Ensembl chr18:26,040,285...26,106,587
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G |
Fam174b |
family with sequence similarity 174, member B |
increases expression |
ISO |
Thapsigargin results in increased expression of FAM174B mRNA |
CTD |
PMID:29453283 |
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NCBI chr 1:127,515,393...127,618,591
Ensembl chr 1:127,514,041...127,596,128
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G |
Fam193a |
family with sequence similarity 193, member A |
increases expression |
ISO |
Thapsigargin results in increased expression of FAM193A protein |
CTD |
PMID:24648495 |
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NCBI chr14:76,250,103...76,382,525
Ensembl chr14:76,256,161...76,382,514
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G |
Fam234a |
family with sequence similarity 234, member A |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FAM234A protein |
CTD |
PMID:24648495 |
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NCBI chr10:15,232,267...15,263,529
Ensembl chr10:15,232,278...15,263,488
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G |
Fam24b |
family with sequence similarity 24 member B |
increases expression |
ISO |
Thapsigargin results in increased expression of FAM24B mRNA |
CTD |
PMID:22378314 PMID:29453283 |
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NCBI chr 1:186,112,544...186,115,998
Ensembl chr 1:186,112,551...186,115,899
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G |
Fam83d |
family with sequence similarity 83, member D |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FAM83D mRNA |
CTD |
PMID:22378314 |
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NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192
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G |
Fanci |
FA complementation group I |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FANCI mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:133,327,297...133,383,640
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G |
Fas |
Fas cell surface death receptor |
increases expression |
ISO |
Thapsigargin results in increased expression of FAS mRNA |
CTD |
PMID:33770205 |
|
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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G |
Fbn2 |
fibrillin 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of FBN2 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr18:51,499,737...51,703,976
Ensembl chr18:51,499,737...51,703,976
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G |
Fbp1 |
fructose-bisphosphatase 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FBP1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
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G |
Fbxo32 |
F-box protein 32 |
increases expression |
ISO |
Thapsigargin results in increased expression of FBXO32 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 7:89,731,626...89,764,761
Ensembl chr 7:89,730,232...89,765,436
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G |
Fdft1 |
farnesyl diphosphate farnesyl transferase 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FDFT1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
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G |
Fdxr |
ferredoxin reductase |
increases expression |
ISO |
Thapsigargin results in increased expression of FDXR mRNA |
CTD |
PMID:22378314 |
|
NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658
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G |
Fgf13 |
fibroblast growth factor 13 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FGF13 mRNA |
CTD |
PMID:19442820 |
|
NCBI chr X:137,276,498...137,800,056
Ensembl chr X:137,276,511...137,800,391
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G |
Fgf21 |
fibroblast growth factor 21 |
multiple interactions increases expression |
ISO |
indolo(3,2-b)carbazole inhibits the reaction [Thapsigargin results in increased expression of FGF21 mRNA]; N-(2-(3H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)purin-6-amine inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Thapsigargin results in increased expression of FGF21 mRNA]]; Tetrachlorodibenzodioxin inhibits the reaction [Thapsigargin results in increased expression of FGF21 mRNA] |
CTD |
PMID:27226639 |
|
NCBI chr 1:96,083,495...96,084,738
Ensembl chr 1:96,083,441...96,090,454
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G |
Fggy |
FGGY carbohydrate kinase domain containing |
increases expression |
ISO |
Thapsigargin results in increased expression of FGGY mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 5:110,398,866...110,786,019
Ensembl chr 5:110,398,863...110,786,017
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G |
Fh |
fumarate hydratase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FH mRNA |
CTD |
PMID:22378314 |
|
NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
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G |
Ficd |
FIC domain protein adenylyltransferase |
increases expression |
ISO |
Thapsigargin results in increased expression of FICD mRNA |
CTD |
PMID:22378314 |
|
NCBI chr12:42,889,195...42,894,090
Ensembl chr12:42,889,194...42,894,070
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G |
Fignl1 |
fidgetin-like 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FIGNL1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr14:86,368,670...86,381,728
Ensembl chr14:86,368,675...86,377,455
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G |
Filip1l |
filamin A interacting protein 1-like |
increases expression |
ISO |
Thapsigargin results in increased expression of FILIP1L protein |
CTD |
PMID:24648495 |
|
NCBI chr11:42,937,353...43,177,085
Ensembl chr11:42,940,467...43,177,415
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G |
Fis1 |
fission, mitochondrial 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of FIS1 mRNA |
CTD |
PMID:28940366 |
|
NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377
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G |
Fjx1 |
four-jointed box kinase 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FJX1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 3:88,774,220...88,776,321
Ensembl chr 3:88,774,220...88,776,321
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G |
Fkbp11 |
FKBP prolyl isomerase 11 |
increases expression |
ISO |
Thapsigargin results in increased expression of FKBP11 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
|
NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303
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G |
Fkbp3 |
FKBP prolyl isomerase 3 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FKBP3 protein |
CTD |
PMID:24648495 |
|
NCBI chr 6:83,113,885...83,125,500
Ensembl chr 6:83,113,786...83,127,011
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G |
Flii |
FLII, actin remodeling protein |
increases expression |
ISO |
Thapsigargin results in increased expression of FLII protein |
CTD |
PMID:24648495 |
|
NCBI chr10:45,394,032...45,408,051
Ensembl chr10:45,394,032...45,407,970
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G |
Flot2 |
flotillin 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FLOT2 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr10:62,926,047...62,947,759
Ensembl chr10:62,920,665...62,947,756
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G |
Flrt2 |
fibronectin leucine rich transmembrane protein 2 |
decreases expression multiple interactions |
ISO |
Thapsigargin results in decreased expression of FLRT2 mRNA 4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of FLRT2 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of FLRT2 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of FLRT2 mRNA] |
CTD |
PMID:19442820 |
|
NCBI chr 6:114,777,547...114,872,688
Ensembl chr 6:114,777,599...114,872,785
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G |
Flt4 |
Fms related receptor tyrosine kinase 4 |
multiple interactions |
ISO |
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of FLT4 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of FLT4 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of FLT4 mRNA] |
CTD |
PMID:19442820 |
|
NCBI chr10:33,913,725...33,954,770
Ensembl chr10:33,913,608...33,954,770
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G |
Fndc3b |
fibronectin type III domain containing 3B |
increases expression |
ISO |
Thapsigargin results in increased expression of FNDC3B mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 2:110,311,439...110,617,504
Ensembl chr 2:110,312,694...110,547,830
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
Thapsigargin results in increased expression of FOS mRNA |
CTD |
PMID:21694771 PMID:29453283 |
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Fosb |
FosB proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
Thapsigargin results in increased expression of FOSB mRNA |
CTD |
PMID:21694771 PMID:29453283 |
|
NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
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G |
Foxd2 |
forkhead box D2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FOXD2 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 5:128,427,986...128,430,869
Ensembl chr 5:128,429,020...128,430,504
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G |
Foxo4 |
forkhead box O4 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FOXO4 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr X:66,385,241...66,392,115
Ensembl chr X:66,385,558...66,392,115
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G |
Fundc2 |
FUN14 domain containing 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FUNDC2 protein |
CTD |
PMID:24648495 |
|
NCBI chr18:128,473...138,232
Ensembl chr18:132,248...138,345
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|
G |
Fzd7 |
frizzled class receptor 7 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FZD7 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781
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|
G |
G3bp1 |
G3BP stress granule assembly factor 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of G3BP1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr10:39,586,864...39,620,268
Ensembl chr10:39,586,864...39,620,268
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|
G |
Gabbr1 |
gamma-aminobutyric acid type B receptor subunit 1 |
affects localization |
EXP |
Thapsigargin affects the localization of GABBR1 protein |
CTD |
PMID:24668805 |
|
NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994
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|
G |
Gabbr2 |
gamma-aminobutyric acid type B receptor subunit 2 |
affects localization |
EXP |
Thapsigargin affects the localization of GABBR2 protein |
CTD |
PMID:24668805 |
|
NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104
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|
G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
increases expression |
ISO |
Thapsigargin results in increased expression of GADD45A mRNA |
CTD |
PMID:17332266 PMID:29453283 PMID:33770205 |
|
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
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|
G |
Gadd45b |
growth arrest and DNA-damage-inducible, beta |
increases expression |
ISO |
Thapsigargin results in increased expression of GADD45B mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
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|
G |
Gadd45g |
growth arrest and DNA-damage-inducible, gamma |
increases expression |
ISO |
Thapsigargin results in increased expression of GADD45G mRNA |
CTD |
PMID:29453283 |
|
NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
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|
G |
Gal |
galanin and GMAP prepropeptide |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GAL mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
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|
G |
Galk2 |
galactokinase 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of GALK2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 3:113,110,057...113,243,014
Ensembl chr 3:113,110,030...113,233,306
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|
G |
Galr2 |
galanin receptor 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of GALR2 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr10:101,513,689...101,517,176
Ensembl chr10:101,514,471...101,517,176
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|
G |
Ganab |
glucosidase II alpha subunit |
increases expression |
ISO |
Thapsigargin results in increased expression of GANAB mRNA Thapsigargin results in increased expression of GANAB protein |
CTD |
PMID:22378314 PMID:24648495 |
|
NCBI chr 1:205,793,810...205,813,701
Ensembl chr 1:205,793,895...205,813,695
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|
G |
Gap43 |
growth associated protein 43 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GAP43 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
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|
G |
Gars1 |
glycyl-tRNA synthetase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of GARS1 mRNA; Thapsigargin results in increased expression of GARS1 protein |
CTD |
PMID:22378314 PMID:29453283 |
|
NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609
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|
G |
Gas1 |
growth arrest-specific 1 |
decreases expression increases expression |
ISO |
Thapsigargin results in decreased expression of GAS1 protein Thapsigargin results in increased expression of GAS1 mRNA |
CTD |
PMID:24648495 PMID:29453283 |
|
NCBI chr17:4,482,014...4,485,155
|
|
G |
Gata2 |
GATA binding protein 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GATA2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
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|
G |
Gcat |
glycine C-acetyltransferase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GCAT mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 7:110,595,126...110,601,474
Ensembl chr 7:110,595,091...110,601,473
|
|
G |
Gcdh |
glutaryl-CoA dehydrogenase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GCDH mRNA |
CTD |
PMID:22378314 |
|
NCBI chr19:23,263,215...23,269,689
Ensembl chr19:23,263,264...23,269,681
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|
G |
Gdf15 |
growth differentiation factor 15 |
increases expression |
ISO |
Thapsigargin results in increased expression of GDF15 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
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|
G |
Gem |
GTP binding protein overexpressed in skeletal muscle |
increases expression |
ISO |
Thapsigargin results in increased expression of GEM mRNA |
CTD |
PMID:21694771 PMID:29453283 |
|
NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
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|
G |
Gemin4 |
gem (nuclear organelle) associated protein 4 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GEMIN4 mRNA |
CTD |
PMID:24247028 |
|
NCBI chr10:61,062,420...61,073,529
Ensembl chr10:61,066,425...61,073,431 Ensembl chr10:61,066,425...61,073,431
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|
G |
Gemin5 |
gem (nuclear organelle) associated protein 5 |
increases expression |
ISO |
Thapsigargin results in increased expression of GEMIN5 protein |
CTD |
PMID:24648495 |
|
NCBI chr10:42,295,729...42,342,902
Ensembl chr10:42,297,515...42,342,892
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|
G |
Gfm1 |
G elongation factor, mitochondrial 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GFM1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 2:151,700,573...151,745,477
Ensembl chr 2:151,700,564...151,745,471
|
|
G |
Gfpt1 |
glutamine fructose-6-phosphate transaminase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of GFPT1 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
|
NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471
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|
G |
Ggct |
gamma-glutamyl cyclotransferase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GGCT protein |
CTD |
PMID:24648495 |
|
NCBI chr 4:84,122,921...84,129,327
Ensembl chr 4:84,123,118...84,129,277
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|
G |
Gins2 |
GINS complex subunit 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GINS2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339
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|
G |
Gla |
galactosidase, alpha |
increases expression |
ISO |
Thapsigargin results in increased expression of GLA mRNA |
CTD |
PMID:29453283 |
|
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
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|
G |
Gldc |
glycine decarboxylase |
decreases expression increases expression |
ISO |
Thapsigargin results in decreased expression of GLDC mRNA Thapsigargin results in increased expression of GLDC mRNA |
CTD |
PMID:22378314 PMID:33770205 |
|
NCBI chr 1:227,883,247...227,962,119
Ensembl chr 1:227,883,249...227,962,097
|
|
G |
Glg1 |
golgi glycoprotein 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of GLG1 protein |
CTD |
PMID:24648495 |
|
NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178
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|
G |
Glo1 |
glyoxalase 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GLO1 protein |
CTD |
PMID:24648495 |
|
NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
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|
G |
Glrx3 |
glutaredoxin 3 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GLRX3 protein |
CTD |
PMID:24648495 |
|
NCBI chr 1:192,241,707...192,272,012
Ensembl chr 1:192,241,701...192,272,010
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|
G |
Gls |
glutaminase |
increases expression |
ISO |
Thapsigargin results in increased expression of GLS mRNA |
CTD |
PMID:22378314 PMID:29453283 |
|
NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
|
|
G |
Gmeb1 |
glucocorticoid modulatory element binding protein 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GMEB1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 5:144,421,151...144,462,448
Ensembl chr 5:144,420,555...144,462,602
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|
G |
Gmnn |
geminin, DNA replication inhibitor |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GMNN mRNA |
CTD |
PMID:22378314 |
|
NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054
|
|
G |
Gmppa |
GDP-mannose pyrophosphorylase A |
increases expression |
ISO |
Thapsigargin results in increased expression of GMPPA mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 9:76,926,724...76,934,274
Ensembl chr 9:76,926,739...76,934,269
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|
G |
Gng12 |
G protein subunit gamma 12 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GNG12 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 4:96,011,118...96,134,767
Ensembl chr 4:96,010,952...96,134,712
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|
G |
Gng2 |
G protein subunit gamma 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GNG2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr15:4,316,038...4,416,918
Ensembl chr15:4,316,059...4,417,183
|
|
G |
Gnl3l |
G protein nucleolar 3 like |
increases expression |
ISO |
Thapsigargin results in increased expression of GNL3L mRNA |
CTD |
PMID:22378314 |
|
NCBI chr X:19,961,277...19,994,454
Ensembl chr X:19,958,603...19,994,508
|
|
G |
Golga2 |
golgin A2 |
increases expression |
ISO |
Thapsigargin results in increased expression of GOLGA2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 3:15,583,862...15,604,279
Ensembl chr 3:15,584,039...15,604,279
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|
G |
Golga3 |
golgin A3 |
increases expression |
ISO |
Thapsigargin results in increased expression of GOLGA3 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr12:46,452,409...46,500,509
Ensembl chr12:46,454,870...46,500,509
|
|
G |
Golga5 |
golgin A5 |
increases expression |
ISO |
Thapsigargin results in increased expression of GOLGA5 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 6:121,612,389...121,640,552
Ensembl chr 6:121,612,529...121,640,413
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|
G |
Gosr1 |
golgi SNAP receptor complex member 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GOSR1 mRNA |
CTD |
PMID:19442820 |
|
NCBI chr10:61,570,499...61,607,287
Ensembl chr10:61,450,494...61,607,177 Ensembl chr10:61,450,494...61,607,177
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|
G |
Got2 |
glutamic-oxaloacetic transaminase 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GOT2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
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|
G |
Gpd2 |
glycerol-3-phosphate dehydrogenase 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of GPD2 protein |
CTD |
PMID:24648495 |
|
NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901
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|
G |
Gpr137b |
G protein-coupled receptor 137B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GPR137B mRNA |
CTD |
PMID:29453283 |
|
NCBI chr17:86,003,630...86,041,841
Ensembl chr17:85,966,921...86,041,835
|
|
G |
Gpr22 |
G protein-coupled receptor 22 |
increases expression |
ISO |
Thapsigargin results in increased expression of GPR22 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 6:48,309,619...48,317,864
Ensembl chr 6:48,310,505...48,317,486
|
|
G |
Gprc5b |
G protein-coupled receptor, class C, group 5, member B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GPRC5B protein |
CTD |
PMID:24648495 |
|
NCBI chr 1:173,316,398...173,340,951
Ensembl chr 1:173,316,907...173,340,932
|
|
G |
Gps2 |
G protein pathway suppressor 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of GPS2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr10:54,637,360...54,640,542
Ensembl chr10:54,637,455...54,640,650
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|
G |
Gpsm2 |
G-protein signaling modulator 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GPSM2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 2:196,327,149...196,375,322
Ensembl chr 2:196,327,149...196,375,154
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|
G |
Gpt2 |
glutamic--pyruvic transaminase 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of GPT2 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
|
NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610
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|
G |
Gpx8 |
glutathione peroxidase 8 |
increases expression |
ISO |
Thapsigargin results in increased expression of GPX8 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 2:44,676,448...44,680,042
Ensembl chr 2:44,676,454...44,680,195
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|
G |
Grcc10 |
gene rich cluster, C10 gene |
increases expression |
ISO |
Thapsigargin results in increased expression of C12ORF57 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 4:157,551,276...157,552,924
|
|
G |
Grpel1 |
GrpE-like 1, mitochondrial |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GRPEL1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr14:74,292,023...74,298,243
Ensembl chr14:74,292,023...74,298,200
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|
G |
Grpel2 |
GrpE-like 2, mitochondrial |
increases expression |
ISO |
Thapsigargin results in increased expression of GRPEL2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr18:55,167,831...55,180,073
Ensembl chr18:55,168,209...55,180,180
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|
G |
Gsdmd |
gasdermin D |
increases expression |
ISO |
Thapsigargin results in increased expression of GSDMD mRNA |
CTD |
PMID:30796460 |
|
NCBI chr 7:107,542,242...107,547,052
Ensembl chr 7:107,542,083...107,547,055
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|
G |
Gsr |
glutathione-disulfide reductase |
multiple interactions decreases expression |
ISO |
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of GSR mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of GSR mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of GSR mRNA] |
CTD |
PMID:19442820 |
|
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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|
G |
H1f2 |
H1.2 linker histone, cluster member |
decreases expression increases expression |
ISO |
Thapsigargin results in decreased expression of H1F2 protein Thapsigargin results in increased expression of H1-2 mRNA |
CTD |
PMID:22378314 PMID:24648495 |
|
NCBI chr17:41,391,106...41,392,611
Ensembl chr17:41,388,477...41,392,635
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|
G |
H1f4 |
H1.4 linker histone, cluster member |
decreases expression |
ISO |
Thapsigargin results in decreased expression of H1F4 protein |
CTD |
PMID:24648495 |
|
NCBI chr17:41,486,634...41,487,293
Ensembl chr17:41,486,560...41,487,403
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|
G |
H2ac20 |
H2A clustered histone 20 |
increases expression |
ISO |
Thapsigargin results in increased expression of H2AC20 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 2:183,779,879...183,780,324
|
|
G |
H2ax |
H2A.X variant histone |
increases expression decreases phosphorylation |
ISO |
Thapsigargin results in increased expression of H2AX mRNA Thapsigargin results in decreased phosphorylation of H2AX protein |
CTD |
PMID:19442820 PMID:32482060 |
|
NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
|
|
G |
Hadha |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
increases expression |
ISO |
Thapsigargin results in increased expression of HADHA protein |
CTD |
PMID:24648495 |
|
NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
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|
G |
Havcr2 |
hepatitis A virus cellular receptor 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of HAVCR2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137
|
|
G |
Hax1 |
HCLS1 associated protein X-1 |
increases expression |
ISO |
Thapsigargin results in increased expression of HAX1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 2:175,434,242...175,437,926
Ensembl chr 2:175,434,238...175,437,714
|
|
G |
Hbegf |
heparin-binding EGF-like growth factor |
increases expression |
ISO |
Thapsigargin results in increased expression of HBEGF mRNA |
CTD |
PMID:29453283 |
|
NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
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|
G |
Hbq1b |
hemoglobin subunit theta 1B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HBQ1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr10:15,334,293...15,336,061
Ensembl chr10:15,320,762...15,321,397 Ensembl chr10:15,320,762...15,321,397
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|
G |
Hcfc1 |
host cell factor C1 |
increases expression |
ISO |
Thapsigargin results in increased expression of HCFC1 protein |
CTD |
PMID:24648495 |
|
NCBI chr X:151,687,779...151,712,688
Ensembl chr X:151,687,779...151,712,638
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|
G |
Hdac5 |
histone deacetylase 5 |
increases expression |
ISO |
Thapsigargin results in increased expression of HDAC5 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235
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|
G |
Hdac6 |
histone deacetylase 6 |
increases expression |
ISO |
Thapsigargin results in increased expression of HDAC6 protein |
CTD |
PMID:24648495 |
|
NCBI chr X:14,550,645...14,572,445
Ensembl chr X:14,551,044...14,572,441
|
|
G |
Hdgf |
heparin binding growth factor |
multiple interactions increases expression |
ISO |
Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in increased expression of HDGF mRNA] |
CTD |
PMID:19442820 |
|
NCBI chr 2:173,370,147...173,379,756
Ensembl chr 2:173,370,465...173,379,747
|
|
G |
Hectd1 |
HECT domain E3 ubiquitin protein ligase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of HECTD1 protein |
CTD |
PMID:24648495 |
|
NCBI chr 6:69,181,429...69,267,803
Ensembl chr 6:69,181,436...69,268,053
|
|
G |
Helb |
DNA helicase B |
increases expression |
ISO |
Thapsigargin results in increased expression of HELB protein |
CTD |
PMID:24648495 |
|
NCBI chr 7:55,588,510...55,615,979
Ensembl chr 7:55,588,798...55,615,585
|
|
G |
Herpud1 |
homocysteine inducible ER protein with ubiquitin like domain 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of HERPUD1 mRNA |
CTD |
PMID:22378314 PMID:27587023 PMID:29453283 |
|
NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
|
|
G |
Hes1 |
hes family bHLH transcription factor 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HES1 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
|
|
G |
Hes6 |
hes family bHLH transcription factor 6 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HES6 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 9:92,001,838...92,003,580
Ensembl chr 9:92,001,841...92,003,559
|
|
G |
Hey1 |
hes-related family bHLH transcription factor with YRPW motif 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HEY1 mRNA |
CTD |
PMID:22378314 PMID:33770205 |
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NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312
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G |
Hgf |
hepatocyte growth factor |
decreases expression multiple interactions |
EXP |
Thapsigargin results in decreased expression of HGF mRNA; Thapsigargin results in decreased expression of HGF protein 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in decreased expression of HGF mRNA]; salubrinal inhibits the reaction [Thapsigargin results in decreased expression of HGF mRNA]; salubrinal inhibits the reaction [Thapsigargin results in decreased expression of HGF protein] |
CTD |
PMID:28844859 |
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NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
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G |
Hgsnat |
heparan-alpha-glucosaminide N-acetyltransferase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HGSNAT protein |
CTD |
PMID:24648495 |
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NCBI chr16:66,105,233...66,137,444
Ensembl chr16:66,105,181...66,136,138
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G |
Hibadh |
3-hydroxyisobutyrate dehydrogenase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HIBADH mRNA |
CTD |
PMID:22378314 |
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NCBI chr 4:81,649,180...81,747,244
Ensembl chr 4:81,649,175...81,780,617
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G |
Hid1 |
HID1 domain containing |
increases expression |
ISO |
Thapsigargin results in increased expression of HID1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr10:100,589,555...100,610,050
Ensembl chr10:100,589,555...100,610,041
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G |
Hikeshi |
heat shock protein nuclear import factor |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HIKESHI protein |
CTD |
PMID:24648495 |
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NCBI chr 1:143,825,922...143,849,374
Ensembl chr 1:143,825,923...143,849,363
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G |
Hist2h2aa3 |
histone cluster 2 H2A family member A3 |
increases expression |
ISO |
Thapsigargin results in increased expression of H2AC18 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 2:183,808,398...183,808,922
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G |
Hist3h2a |
histone cluster 3, H2a |
increases expression |
ISO |
Thapsigargin results in increased expression of H2AW mRNA |
CTD |
PMID:22378314 |
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NCBI chr10:43,733,702...43,735,254
Ensembl chr10:43,733,668...43,744,874
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G |
Hk1 |
hexokinase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of HK1 protein |
CTD |
PMID:24648495 |
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NCBI chr20:30,230,488...30,332,161
Ensembl chr20:30,230,486...30,332,131
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G |
Hk2 |
hexokinase 2 |
increases expression decreases expression |
ISO |
Thapsigargin results in increased expression of HK2 mRNA Thapsigargin results in decreased expression of HK2 mRNA |
CTD |
PMID:21694771 PMID:22378314 |
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NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
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G |
Hlcs |
holocarboxylase synthetase |
increases expression |
ISO |
Thapsigargin results in increased expression of HLCS mRNA |
CTD |
PMID:22378314 |
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NCBI chr11:33,455,806...33,635,197
Ensembl chr11:33,455,809...33,624,222
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G |
Hltf |
helicase-like transcription factor |
increases expression |
ISO |
Thapsigargin results in increased expression of HLTF protein |
CTD |
PMID:24648495 |
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NCBI chr 2:102,549,724...102,609,492
Ensembl chr 2:102,549,724...102,609,327
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G |
Hm13 |
histocompatibility minor 13 |
increases expression |
ISO |
Thapsigargin results in increased expression of HM13 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 3:141,145,769...141,184,703
Ensembl chr 3:141,145,782...141,184,703
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G |
Hmbs |
hydroxymethylbilane synthase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HMBS protein |
CTD |
PMID:24648495 |
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NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957
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G |
Hmgcl |
3-hydroxy-3-methylglutaryl-CoA lyase |
increases expression |
ISO |
Thapsigargin results in increased expression of HMGCL mRNA |
CTD |
PMID:22378314 |
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NCBI chr 5:148,178,203...148,192,072
Ensembl chr 5:148,178,252...148,192,068
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
decreases expression increases expression |
ISO |
Thapsigargin results in decreased expression of HMGCR mRNA Thapsigargin results in increased expression of HMGCR mRNA |
CTD |
PMID:22378314 PMID:29453283 |
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NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
decreases expression increases expression |
ISO |
Thapsigargin results in decreased expression of HMGCS1 mRNA Thapsigargin results in increased expression of HMGCS1 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
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NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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G |
Hmox1 |
heme oxygenase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of HMOX1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hmx1 |
H6 family homeobox 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HMX1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr14:75,361,207...75,364,993
Ensembl chr14:75,361,225...75,364,993
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G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
decreases expression multiple interactions |
ISO |
Thapsigargin results in decreased expression of HNF4A mRNA; Thapsigargin results in decreased expression of HNF4A protein Thapsigargin promotes the reaction [HNF4A protein binds to NR1I2 promoter] |
CTD |
PMID:25616597 |
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NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
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G |
Hnrnpa1 |
heterogeneous nuclear ribonucleoprotein A1 |
multiple interactions affects localization |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Thapsigargin affects the localization of HNRNPA1 protein]; Thapsigargin promotes the reaction [HNRNPA1 protein binds to SREBF1 5' UTR] |
CTD |
PMID:23106379 |
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NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
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G |
Hnrnpa2b1 |
heterogeneous nuclear ribonucleoprotein A2/B1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HNRNPA2B1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
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G |
Hnrnpa3 |
heterogeneous nuclear ribonucleoprotein A3 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HNRNPA3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 3:60,578,574...60,588,755
Ensembl chr 3:60,578,673...60,588,306
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G |
Hook3 |
hook microtubule-tethering protein 3 |
increases expression |
ISO |
Thapsigargin results in increased expression of HOOK3 protein |
CTD |
PMID:24648495 |
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NCBI chr16:65,954,293...66,058,812
Ensembl chr16:65,954,350...66,061,338
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G |
Hoxa10 |
homeobox A10 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HOXA10 mRNA |
CTD |
PMID:29453283 |
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G |
Hoxa11-as |
HOXA11 antisense RNA |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HOXA11-AS mRNA |
CTD |
PMID:29453283 |
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NCBI chr 4:81,346,416...81,350,190
Ensembl chr 4:81,346,416...81,350,179
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G |
Hoxa13 |
homeo box A13 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HOXA13 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 4:81,358,956...81,361,091
Ensembl chr 4:81,358,956...81,361,091
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G |
Hoxb5 |
homeo box B5 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HOXB5 mRNA |
CTD |
PMID:29453283 |
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NCBI chr10:81,269,372...81,271,580
Ensembl chr10:81,269,372...81,271,580
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G |
Hoxc13 |
homeobox C13 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HOXC13 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 7:134,058,640...134,065,479
Ensembl chr 7:134,058,640...134,064,800
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G |
Hoxc8 |
homeobox C8 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HOXC8 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 7:134,127,937...134,130,503
Ensembl chr 7:134,127,913...134,130,503
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G |
Hoxc9 |
homeobox C9 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HOXC9 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 7:134,118,817...134,121,497
Ensembl chr 7:134,118,817...134,121,492
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G |
Hpca |
hippocalcin |
decreases response to substance |
ISO |
HPCA protein results in decreased susceptibility to Thapsigargin |
CTD |
PMID:15607944 |
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NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841
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G |
Hprt1 |
hypoxanthine phosphoribosyltransferase 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HPRT1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154
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G |
Hr |
HR, lysine demethylase and nuclear receptor corepressor |
affects response to substance multiple interactions |
ISO |
HR protein affects the susceptibility to Thapsigargin HR protein affects the reaction [Thapsigargin results in increased activity of CASP3 protein] |
CTD |
PMID:20886113 |
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NCBI chr15:45,626,835...45,646,313
Ensembl chr15:45,626,835...45,646,313
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G |
Hras |
HRas proto-oncogene, GTPase |
multiple interactions |
ISO |
[Thapsigargin co-treated with HRAS protein] results in decreased phosphorylation of MAPK1 protein; [Thapsigargin co-treated with HRAS protein] results in decreased phosphorylation of MAPK3 protein; [Thapsigargin co-treated with HRAS protein] results in increased expression of EIF2AK3 protein; [Thapsigargin co-treated with HRAS protein] results in increased expression of ERN1 protein; [Thapsigargin co-treated with HRAS protein] results in increased expression of HSPA5 protein; [Thapsigargin co-treated with HRAS protein] results in increased phosphorylation of AKT1 protein |
CTD |
PMID:24898257 |
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NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
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G |
Hscb |
HscB mitochondrial iron-sulfur cluster co-chaperone |
increases expression |
ISO |
Thapsigargin results in increased expression of HSCB mRNA |
CTD |
PMID:22378314 |
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NCBI chr12:45,821,527...45,831,902
Ensembl chr12:45,821,555...45,831,909
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G |
Hsd17b10 |
hydroxysteroid (17-beta) dehydrogenase 10 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HSD17B10 mRNA |
CTD |
PMID:22378314 |
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NCBI chr X:21,089,152...21,091,597
Ensembl chr X:21,089,122...21,109,488
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G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HSP90AA1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
multiple interactions increases expression decreases expression |
ISO EXP |
Apigenin inhibits the reaction [Thapsigargin results in increased expression of HSP90B1 protein]; Thapsigargin promotes the reaction [arsenic trioxide results in increased expression of HSP90B1 protein] Thapsigargin results in increased expression of HSP90B1 mRNA; Thapsigargin results in increased expression of HSP90B1 protein 4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of HSP90B1 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of HSP90B1 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of HSP90B1 mRNA] |
CTD |
PMID:15292203 PMID:17416481 PMID:19442820 PMID:20493918 PMID:22378314 PMID:27587023 PMID:27638049 PMID:29453283 More...
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NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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G |
Hspa1b |
heat shock protein family A (Hsp70) member 1B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HSPA1B mRNA |
CTD |
PMID:22378314 |
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NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
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G |
Hspa1l |
heat shock protein family A (Hsp70) member 1 like |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HSPA1L mRNA |
CTD |
PMID:22378314 |
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NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions increases expression |
ISO EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Thapsigargin results in increased expression of HSPA5 mRNA]; [HSPA5 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin; ATF6 promotes the reaction [Thapsigargin results in increased expression of HSPA5 protein]; demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; Doxorubicin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; EIF2AK3 promotes the reaction [Thapsigargin results in increased expression of HSPA5 protein]; Quercetin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 mRNA]; Quercetin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased expression of HSPA5 protein]; ursodoxicoltaurine inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; Wortmannin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 mRNA] [Thapsigargin co-treated with HRAS protein] results in increased expression of HSPA5 protein; Acetylcysteine inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; Apigenin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; Glutathione inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; PTPN1 gene mutant form promotes the reaction [Thapsigargin results in increased expression of HSPA5 mRNA]; PTPN1 gene mutant form promotes the reaction [Thapsigargin results in increased expression of HSPA5 protein]; Thapsigargin promotes the reaction [arsenic trioxide results in increased expression of HSPA5 protein]; Vaticanol B inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein] 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; Dactinomycin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 mRNA]; Dactinomycin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; GW 506033X inhibits the reaction [Thapsigargin results in increased expression of HSPA5 mRNA] Thapsigargin results in increased expression of HSPA5; Thapsigargin results in increased expression of HSPA5 mRNA; Thapsigargin results in increased expression of HSPA5 protein |
CTD |
PMID:12147617 PMID:12198651 PMID:14610226 PMID:15019097 PMID:16236328 PMID:16298333 PMID:16338971 PMID:17283163 PMID:17332266 PMID:17353921 PMID:17416481 PMID:17475668 PMID:17915553 PMID:18477628 PMID:18799549 PMID:19135031 PMID:19139269 PMID:19428936 PMID:20477944 PMID:20493918 PMID:20589738 PMID:20626587 PMID:21198628 PMID:21320468 PMID:21692457 PMID:21694771 PMID:22378314 PMID:22425709 PMID:22509299 PMID:22800509 PMID:23885834 PMID:24898257 PMID:25324550 PMID:25341683 PMID:25611565 PMID:26085089 PMID:26264395 PMID:27358234 PMID:27578021 PMID:27587023 PMID:27638049 PMID:28223344 PMID:28315715 PMID:28844859 PMID:29126784 PMID:29453283 PMID:32357311 PMID:32535746 PMID:32574669 PMID:35033536 More...
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HSPA8 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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G |
Hspa9 |
heat shock protein family A (Hsp70) member 9 |
decreases expression increases expression |
ISO |
Thapsigargin results in decreased expression of HSPA9 protein Thapsigargin results in increased expression of HSPA9 mRNA |
CTD |
PMID:21692457 PMID:22378314 PMID:28942281 |
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NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
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G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
decreases expression increases expression |
ISO |
Thapsigargin results in decreased expression of HSPD1 mRNA Thapsigargin results in increased expression of HSPD1 mRNA |
CTD |
PMID:22378314 PMID:28942281 |
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NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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G |
Hspe1 |
heat shock protein family E (Hsp10) member 1 |
multiple interactions increases expression decreases expression |
ISO |
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in increased expression of HSPE1 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in increased expression of HSPE1 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in increased expression of HSPE1 mRNA] Thapsigargin results in decreased expression of HSPE1 mRNA |
CTD |
PMID:19442820 PMID:22378314 |
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NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
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G |
Hsph1 |
heat shock protein family H (Hsp110) member 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of HSPH1 protein |
CTD |
PMID:24648495 |
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NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
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G |
Htatip2 |
HIV-1 Tat interactive protein 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of HTATIP2 protein |
CTD |
PMID:24648495 |
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NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
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G |
Htr1a |
5-hydroxytryptamine receptor 1A |
increases activity |
ISO |
Thapsigargin results in increased activity of HTR1A protein |
CTD |
PMID:11356925 |
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NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442
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G |
Hyou1 |
hypoxia up-regulated 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of HYOU1 mRNA; Thapsigargin results in increased expression of HYOU1 protein |
CTD |
PMID:22378314 PMID:29453283 |
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NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
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G |
Ibtk |
inhibitor of Bruton tyrosine kinase |
multiple interactions increases expression |
ISO |
ATF4 gene mutant form inhibits the reaction [Thapsigargin results in increased expression of IBTK mRNA alternative form]; EIF2AK3 gene mutant form inhibits the reaction [Thapsigargin results in increased expression of IBTK mRNA alternative form]; EIF2S1 protein mutant form inhibits the reaction [Thapsigargin results in increased expression of IBTK mRNA alternative form] Thapsigargin results in increased expression of IBTK protein |
CTD |
PMID:24648495 |
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NCBI chr 8:86,625,591...86,698,661
Ensembl chr 8:86,625,597...86,698,260
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G |
Id2 |
inhibitor of DNA binding 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of ID2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
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G |
Id3 |
inhibitor of DNA binding 3, HLH protein |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ID3 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
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G |
Idh3a |
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha |
increases expression |
ISO |
Thapsigargin results in increased expression of IDH3A mRNA |
CTD |
PMID:22378314 |
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NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084
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G |
Ifitm2 |
interferon induced transmembrane protein 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of IFITM2 protein |
CTD |
PMID:24648495 |
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NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741
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G |
Ifrd1 |
interferon-related developmental regulator 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of IFRD1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
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G |
Ift20 |
intraflagellar transport 20 |
increases expression |
ISO |
Thapsigargin results in increased expression of IFT20 mRNA |
CTD |
PMID:22378314 |
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NCBI chr10:63,432,597...63,438,125
Ensembl chr10:63,432,633...63,438,124
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G |
Igfbp2 |
insulin-like growth factor binding protein 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of IGFBP2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
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G |
Igfbp3 |
insulin-like growth factor binding protein 3 |
increases expression |
ISO |
Thapsigargin results in increased expression of IGFBP3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
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G |
Igfbp4 |
insulin-like growth factor binding protein 4 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of IGFBP4 protein |
CTD |
PMID:24648495 |
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NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
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G |
Igfbp5 |
insulin-like growth factor binding protein 5 |
increases expression decreases expression |
ISO |
Thapsigargin results in increased expression of IGFBP5 mRNA Thapsigargin results in decreased expression of IGFBP5 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
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NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
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G |
Il18 |
interleukin 18 |
increases expression |
ISO |
Thapsigargin results in increased expression of IL18 mRNA |
CTD |
PMID:30796460 |
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NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression |
ISO |
Thapsigargin inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA] Thapsigargin results in increased expression of IL1B mRNA |
CTD |
PMID:18799549 PMID:30796460 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il21r |
interleukin 21 receptor |
multiple interactions |
ISO |
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of IL21R mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of IL21R mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of IL21R mRNA] |
CTD |
PMID:19442820 |
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NCBI chr 1:180,168,028...180,195,690
Ensembl chr 1:180,168,097...180,195,522
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G |
Il4 |
interleukin 4 |
multiple interactions |
ISO |
Thapsigargin inhibits the reaction [bisphenol A results in increased expression of IL4 protein]; Thapsigargin inhibits the reaction [nonylphenol results in increased expression of IL4 protein] |
CTD |
PMID:12709020 |
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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Il6 |
interleukin 6 |
multiple interactions increases expression |
EXP ISO |
Thapsigargin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein] Thapsigargin promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] Thapsigargin results in increased expression of IL6 mRNA |
CTD |
PMID:18951912 PMID:19285962 PMID:20682585 PMID:21694771 PMID:25616597 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Il6st |
interleukin 6 cytokine family signal transducer |
decreases expression |
EXP |
Thapsigargin results in decreased expression of IL6ST protein |
CTD |
PMID:19285962 |
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NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936
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G |
Ina |
internexin neuronal intermediate filament protein, alpha |
increases expression |
ISO |
Thapsigargin results in increased expression of INA mRNA |
CTD |
PMID:29453283 |
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NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330
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G |
Incenp |
inner centromere protein |
increases expression |
ISO |
Thapsigargin results in increased expression of INCENP protein |
CTD |
PMID:24648495 |
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NCBI chr 1:206,520,655...206,550,575
Ensembl chr 1:206,523,380...206,553,265
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G |
Inhba |
inhibin subunit beta A |
increases expression |
ISO |
Thapsigargin results in increased expression of INHBA mRNA |
CTD |
PMID:21694771 |
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NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
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G |
Inhbe |
inhibin subunit beta E |
increases expression |
ISO |
Thapsigargin results in increased expression of INHBE mRNA |
CTD |
PMID:22935518 |
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NCBI chr 7:63,177,558...63,178,983
Ensembl chr 7:63,176,219...63,179,172
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Ins2 |
insulin 2 |
multiple interactions |
ISO |
Thapsigargin inhibits the reaction [ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]]; Thapsigargin inhibits the reaction [Glucose results in increased secretion of INS protein alternative form]; Thapsigargin inhibits the reaction [NCOA4 protein inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]] |
CTD |
PMID:31776611 PMID:32283200 |
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Insig1 |
insulin induced gene 1 |
decreases expression increases expression |
ISO |
Thapsigargin results in decreased expression of INSIG1 mRNA Thapsigargin results in increased expression of INSIG1 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
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NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
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G |
Insm2 |
INSM transcriptional repressor 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of INSM2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 6:72,973,897...72,977,777
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G |
Ints4 |
integrator complex subunit 4 |
increases expression |
ISO |
Thapsigargin results in increased expression of INTS4 protein |
CTD |
PMID:24648495 |
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NCBI chr 1:151,790,062...151,853,827
Ensembl chr 1:151,786,553...151,853,827
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Ints6 |
integrator complex subunit 6 |
increases expression |
ISO |
Thapsigargin results in increased expression of INTS6 protein |
CTD |
PMID:24648495 |
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NCBI chr15:36,908,966...37,048,043
Ensembl chr15:36,933,724...37,021,527
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G |
Ipo5 |
importin 5 |
increases expression |
ISO |
Thapsigargin results in increased expression of IPO5 protein |
CTD |
PMID:24648495 |
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NCBI chr15:97,990,755...98,041,074
Ensembl chr15:98,005,299...98,041,126
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G |
Iqgap1 |
IQ motif containing GTPase activating protein 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of IQGAP1 protein |
CTD |
PMID:24648495 |
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NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
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Irf7 |
interferon regulatory factor 7 |
increases expression |
ISO |
Thapsigargin results in increased expression of IRF7 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
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Irs1 |
insulin receptor substrate 1 |
multiple interactions |
ISO |
Thapsigargin affects the phosphorylation of and results in decreased expression of IRS1 protein |
CTD |
PMID:22378314 |
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NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
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Irx3 |
iroquois homeobox 3 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of IRX3 mRNA |
CTD |
PMID:29453283 |
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NCBI chr19:15,211,882...15,215,323
Ensembl chr19:15,211,878...15,215,317
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G |
Iscu |
iron-sulfur cluster assembly enzyme |
increases expression |
ISO |
Thapsigargin results in increased expression of ISCU mRNA |
CTD |
PMID:22378314 |
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NCBI chr12:42,852,305...42,858,150
Ensembl chr12:42,852,305...42,858,150
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G |
Isg15 |
ISG15 ubiquitin-like modifier |
increases expression |
ISO |
Thapsigargin results in increased expression of ISG15 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435
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G |
Islr2 |
immunoglobulin superfamily containing leucine-rich repeat 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ISLR2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 8:58,608,165...58,616,246
Ensembl chr 8:58,608,709...58,614,650
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G |
Isoc1 |
isochorismatase domain containing 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ISOC1 mRNA Thapsigargin results in decreased expression of ISOC1 protein |
CTD |
PMID:22378314 PMID:24648495 |
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NCBI chr18:52,158,790...52,179,206
Ensembl chr18:52,158,790...52,178,703
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G |
Itgb5 |
integrin subunit beta 5 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ITGB5 protein |
CTD |
PMID:24648495 |
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NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472
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G |
Itpr1 |
inositol 1,4,5-trisphosphate receptor, type 1 |
increases expression |
ISO |
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