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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 1.14.18.1 (tyrosinase) inhibitor
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Accession:CHEBI:59997 term browser browse the term
Definition:Any EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitor that interferes with the action of tyrosinase (monophenol monooxygenase), EC 1.14.18.1, an enzyme that catalyses the oxidation of phenols (such as tyrosine) and is widespread in plants and animals.
Synonyms:related_synonym: EC 1.14.18.1 inhibitor;   EC 1.14.18.1 inhibitors;   L-tyrosine,L-dopa:oxygen oxidoreductase inhibitor;   L-tyrosine,L-dopa:oxygen oxidoreductase inhibitors;   NN-acetyl-6-hydroxytryptophan oxidase inhibitor;   NN-acetyl-6-hydroxytryptophan oxidase inhibitors;   O-diphenol:O2 oxidoreductase inhibitor;   O-diphenol:O2 oxidoreductase inhibitors;   cresolase inhibitor;   cresolase inhibitors;   monophenol dihydroxyphenylalanine:oxygen oxidoreductase inhibitor;   monophenol dihydroxyphenylalanine:oxygen oxidoreductase inhibitors;   monophenol monooxidase inhibitor;   monophenol monooxidase inhibitors;   monophenol monooxygenase inhibitor;   monophenol monooxygenase inhibitors;   monophenol oxidase inhibitor;   monophenol oxidase inhibitors;   monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase inhibitor;   monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase inhibitors;   monophenolase inhibitor;   monophenolase inhibitors;   phenol oxidase inhibitor;   phenol oxidase inhibitors;   phenolase inhibitor;   phenolase inhibitors;   tyrosinase (EC 1.14.18.1) inhibitors;   tyrosinase inhibitor;   tyrosinase inhibitors;   tyrosine-dopa oxidase inhibitor;   tyrosine-dopa oxidase inhibitors


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brazilein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 decreases expression ISO brazilein results in decreased expression of CCND1 mRNA; brazilein results in decreased expression of CCND1 protein CTD PMID:23948132 NCBI chr 1:200,089,002...200,098,524 JBrowse link
G Ctnnb1 catenin beta 1 decreases expression ISO brazilein results in decreased expression of CTNNB1 protein CTD PMID:23948132 NCBI chr 8:120,640,008...120,667,110 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases expression ISO brazilein results in decreased expression of GSK3B protein modified form CTD PMID:23948132 NCBI chr11:62,498,997...62,648,665 JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases expression
ISO brazilein promotes the reaction [SB 203580 results in decreased expression of and results in decreased activity of MMP2 protein]; brazilein promotes the reaction [wortmannin results in decreased expression of and results in decreased activity of MMP2 protein]; brazilein results in decreased expression of and results in decreased activity of MMP2 protein; SB 203580 promotes the reaction [brazilein results in decreased expression of and results in decreased activity of MMP2 protein]; wortmannin promotes the reaction [brazilein results in decreased expression of and results in decreased activity of MMP2 protein]
brazilein results in decreased expression of MMP2 mRNA
CTD PMID:23707804 NCBI chr19:14,154,657...14,182,870 JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO brazilein results in decreased expression of and results in decreased phosphorylation of NFKBIA protein CTD PMID:23707804 NCBI chr 6:72,858,713...72,861,941 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases expression ISO brazilein results in decreased expression of RELA protein CTD PMID:23707804 NCBI chr 1:202,925,001...202,935,484 JBrowse link
corilagin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase multiple interactions EXP corilagin inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:30582900 NCBI chr 3:89,842,393...89,874,577 JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions EXP corilagin inhibits the reaction [1-naphthyl isothiocyanate decreases expression of nr1h4 mRNA and protein in rat liver]; corilagin increases expression of nr1h4 mRNA and protein in rat embryonic liver cells RGD PMID:29235094 RGD:15042872 NCBI chr 7:23,846,122...23,942,085 JBrowse link
G Tnf tumor necrosis factor decreases secretion ISO corilagin results in decreased secretion of TNF protein CTD PMID:12628509 NCBI chr20:3,622,011...3,624,629 JBrowse link
dioscin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions EXP dioscin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB11 mRNA]; dioscin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB11 protein] CTD PMID:27317372 NCBI chr 3:54,016,854...54,112,797 JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression ISO
EXP
dioscin results in decreased expression of ABCB1 mRNA; dioscin results in decreased expression of ABCB1 protein CTD PMID:24680847 NCBI chr 4:25,357,467...25,529,941 JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions EXP dioscin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA]; dioscin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 protein] CTD PMID:27317372 NCBI chr 1:242,664,657...242,723,239 JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain multiple interactions EXP
ISO
dioscin inhibits the reaction [Ethanol results in decreased expression of ACADM protein] CTD PMID:24146112 NCBI chr 2:242,858,865...242,883,036 JBrowse link
G Acads acyl-CoA dehydrogenase short chain multiple interactions ISO
EXP
dioscin inhibits the reaction [Ethanol results in decreased expression of ACADS protein] CTD PMID:24146112 NCBI chr12:41,493,650...41,502,897 JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions EXP
ISO
dioscin inhibits the reaction [Ethanol results in decreased expression of ACOX1 mRNA] CTD PMID:24146112 NCBI chr10:101,406,197...101,431,242 JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 multiple interactions ISO
EXP
dioscin inhibits the reaction [Ethanol results in decreased expression of ACSL1 protein] CTD PMID:24146112 NCBI chr16:45,755,246...45,821,541 JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 multiple interactions ISO
EXP
dioscin inhibits the reaction [Ethanol results in decreased expression of ACSL5 protein] CTD PMID:24146112 NCBI chr 1:254,289,513...254,336,608 JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases expression
ISO dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of AKT1 protein]
dioscin results in decreased expression of AKT1 mRNA
CTD PMID:25111127 PMID:29990575 NCBI chr 6:131,713,716...131,735,319 JBrowse link
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 multiple interactions ISO
EXP
dioscin inhibits the reaction [Ethanol results in decreased expression of ALDH7A1 protein] CTD PMID:24146112 NCBI chr18:50,003,242...50,042,193 JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression ISO dioscin results in decreased expression of APAF1 mRNA CTD PMID:33359023 NCBI chr 7:25,494,143...25,579,540 JBrowse link
G Atf6 activating transcription factor 6 multiple interactions EXP
ISO
dioscin inhibits the reaction [Ethanol results in increased expression of ATF6 protein] CTD PMID:24146112 NCBI chr13:82,927,579...83,106,381 JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO dioscin results in increased expression of BAD mRNA CTD PMID:33359023 NCBI chr 1:204,133,502...204,142,829 JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases expression
ISO dioscin inhibits the reaction [Acetaminophen results in increased expression of BAK1 protein]
dioscin results in increased expression of BAK1 mRNA; dioscin results in increased expression of BAK1 protein
CTD PMID:22334414 PMID:22939915 PMID:29990575 PMID:33359023 NCBI chr20:5,100,480...5,109,669 JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO dioscin inhibits the reaction [Acetaminophen results in increased expression of BAX protein]
dioscin results in increased expression of BAX mRNA; dioscin results in increased expression of BAX protein
CTD PMID:22334414 PMID:22939915 PMID:33359023 NCBI chr 1:95,940,001...95,945,407 JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO dioscin results in increased expression of BBC3 mRNA; dioscin results in increased expression of BBC3 protein CTD PMID:29990575 PMID:33359023 NCBI chr 1:77,013,281...77,022,509 JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
decreases expression
ISO dioscin inhibits the reaction [Acetaminophen results in decreased expression of BCL2 protein]
dioscin results in increased expression of BCL2 protein
dioscin results in decreased expression of BCL2 mRNA; dioscin results in decreased expression of BCL2 protein
CTD PMID:22334414 PMID:22939915 PMID:24742230 PMID:29990575 PMID:33359023 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO dioscin results in decreased expression of BCL2L1 mRNA; dioscin results in decreased expression of BCL2L1 protein CTD PMID:22334414 PMID:29990575 PMID:33359023 NCBI chr 3:141,253,508...141,304,582 JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
decreases expression
ISO [Acetaminophen co-treated with dioscin] results in increased expression of BID protein
dioscin results in decreased expression of BID mRNA; dioscin results in decreased expression of BID protein
CTD PMID:22334414 PMID:22939915 NCBI chr 4:154,113,198...154,136,353 JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO dioscin results in increased expression of BIRC5 mRNA CTD PMID:29990575 NCBI chr10:103,072,530...103,081,382 JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression
increases expression
increases activity
EXP
ISO
dioscin inhibits the reaction [Ethanol results in increased expression of CASP3 protein]
dioscin results in decreased expression of CASP3 mRNA; dioscin results in decreased expression of CASP3 protein
dioscin results in increased expression of CASP3 mRNA; dioscin results in increased expression of CASP3 protein
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [dioscin results in increased expression of CASP3 protein]; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [dioscin results in increased expression of CASP3 protein]
dioscin results in increased activity of CASP3 protein
CTD PMID:22334414 PMID:24146112 PMID:29990575 PMID:33359023 NCBI chr16:45,662,910...45,681,171 JBrowse link
G Casp7 caspase 7 increases expression ISO dioscin results in increased expression of CASP7 mRNA CTD PMID:29990575 NCBI chr 1:255,437,195...255,476,737 JBrowse link
G Casp8 caspase 8 increases activity
multiple interactions
decreases expression
increases expression
ISO dioscin results in increased activity of CASP8 protein
dioscin results in decreased expression of and results in increased cleavage of CASP8 protein
dioscin results in decreased expression of CASP8 mRNA
dioscin results in increased expression of CASP8 mRNA; dioscin results in increased expression of CASP8 protein
CTD PMID:22334414 PMID:29990575 PMID:33359023 NCBI chr 9:60,263,863...60,312,542 JBrowse link
G Casp9 caspase 9 multiple interactions
decreases expression
increases expression
EXP
ISO
dioscin inhibits the reaction [Ethanol results in increased expression of CASP9 protein]
dioscin results in decreased expression of CASP9 mRNA; dioscin results in decreased expression of CASP9 protein
dioscin results in increased expression of CASP9 mRNA; dioscin results in increased expression of CASP9 protein
CTD PMID:24146112 PMID:29990575 PMID:33359023 NCBI chr 5:154,108,872...154,126,628 JBrowse link
G Ccna2 cyclin A2 decreases expression ISO dioscin results in decreased expression of CCNA2 mRNA; dioscin results in decreased expression of CCNA2 protein CTD PMID:33359023 NCBI chr 2:119,427,239...119,433,645 JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO dioscin results in decreased expression of CCNB1 mRNA; dioscin results in decreased expression of CCNB1 protein CTD PMID:29990575 NCBI chr 2:31,912,190...31,921,163 JBrowse link
G Ccnd1 cyclin D1 increases expression
decreases expression
ISO dioscin results in increased expression of CCND1 mRNA
dioscin results in decreased expression of CCND1 mRNA; dioscin results in decreased expression of CCND1 protein
CTD PMID:29990575 PMID:33359023 NCBI chr 1:200,089,002...200,098,524 JBrowse link
G Ccne1 cyclin E1 decreases expression ISO dioscin results in decreased expression of CCNE1 mRNA; dioscin results in decreased expression of CCNE1 protein CTD PMID:33359023 NCBI chr 1:90,781,947...90,791,188 JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO dioscin results in decreased expression of CDK1 mRNA; dioscin results in decreased expression of CDK1 protein CTD PMID:29990575 NCBI chr20:19,266,226...19,281,417 JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO dioscin results in decreased expression of CDK2 mRNA; dioscin results in decreased expression of CDK2 protein CTD PMID:33359023 NCBI chr 7:1,129,878...1,137,431 JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO dioscin results in decreased expression of CDK4 mRNA CTD PMID:33359023 NCBI chr 7:62,885,647...62,889,562 JBrowse link
G Cdk6 cyclin-dependent kinase 6 decreases expression ISO dioscin results in decreased expression of CDK6 mRNA; dioscin results in decreased expression of CDK6 protein CTD PMID:33359023 NCBI chr 4:30,637,650...30,829,688 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO dioscin results in increased expression of CDKN1A mRNA; dioscin results in increased expression of CDKN1A protein CTD PMID:29990575 PMID:33359023 NCBI chr20:7,149,177...7,159,727 JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO dioscin results in increased expression of CDKN1B mRNA; dioscin results in increased expression of CDKN1B protein CTD PMID:33359023 NCBI chr 4:167,760,067...167,765,177 JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression ISO dioscin results in increased expression of CDKN2A mRNA; dioscin results in increased expression of CDKN2A protein CTD PMID:33359023 NCBI chr 5:103,984,949...103,992,143 JBrowse link
G Chek1 checkpoint kinase 1 decreases expression ISO dioscin results in decreased expression of CHEK1 mRNA; dioscin results in decreased expression of CHEK1 protein CTD PMID:33359023 NCBI chr 8:36,420,565...36,443,477 JBrowse link
G Chek2 checkpoint kinase 2 decreases expression ISO dioscin results in decreased expression of CHEK2 mRNA; dioscin results in decreased expression of CHEK2 protein CTD PMID:29990575 NCBI chr12:45,788,823...45,821,382 JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO
EXP
dioscin inhibits the reaction [Ethanol results in decreased expression of CPT1A mRNA] CTD PMID:24146112 NCBI chr 1:200,564,634...200,627,059 JBrowse link
G Ctnnb1 catenin beta 1 increases expression
multiple interactions
ISO dioscin results in increased expression of CTNNB1 mRNA; dioscin results in increased expression of CTNNB1 protein
fulvestrant inhibits the reaction [dioscin results in increased expression of CTNNB1 mRNA]
CTD PMID:24742230 NCBI chr 8:120,640,008...120,667,110 JBrowse link
G Cycs cytochrome c, somatic increases expression ISO dioscin results in increased expression of CYCS mRNA CTD PMID:33359023 NCBI chr 4:79,651,894...79,653,994 JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO
EXP
dioscin inhibits the reaction [Acetaminophen results in increased expression of and results in increased activity of CYP2E1 protein]; dioscin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:22939915 PMID:24146112 NCBI chr 1:195,840,330...195,850,728 JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO
EXP
dioscin inhibits the reaction [Ethanol results in increased expression of DGAT1 mRNA] CTD PMID:24146112 NCBI chr 7:108,223,860...108,235,413 JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions ISO
EXP
dioscin inhibits the reaction [Ethanol results in increased expression of DGAT2 mRNA] CTD PMID:24146112 NCBI chr 1:153,454,078...153,484,432 JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein increases expression ISO dioscin results in increased expression of DIABLO mRNA CTD PMID:29990575 NCBI chr12:33,055,784...33,070,400 JBrowse link
G Esr1 estrogen receptor 1 increases expression
multiple interactions
ISO dioscin results in increased expression of ESR1 protein
fulvestrant inhibits the reaction [dioscin results in increased expression of ESR1 protein]
CTD PMID:24742230 NCBI chr 1:41,106,335...41,499,104 JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [dioscin results in increased expression of ESR2 protein] CTD PMID:24742230 NCBI chr 6:94,858,438...94,909,630 JBrowse link
G Fadd Fas associated via death domain increases expression ISO dioscin results in increased expression of FADD mRNA; dioscin results in increased expression of FADD protein CTD PMID:22334414 PMID:29990575 PMID:33359023 NCBI chr 1:199,743,200...199,745,746 JBrowse link
G Fas Fas cell surface death receptor increases expression ISO dioscin results in increased expression of FAS mRNA; dioscin results in increased expression of FAS protein CTD PMID:22334414 PMID:33359023 NCBI chr 1:231,798,963...231,832,591 JBrowse link
G Faslg Fas ligand increases expression ISO dioscin results in increased expression of FASLG mRNA; dioscin results in increased expression of FASLG protein CTD PMID:22334414 PMID:29990575 NCBI chr13:74,151,519...74,172,760 JBrowse link
G Foxo1 forkhead box O1 increases expression ISO dioscin results in increased expression of FOXO1 mRNA CTD PMID:33359023 NCBI chr 2:136,312,168...136,390,603 JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP dioscin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of GPT protein] CTD PMID:27317372 NCBI chr 7:108,416,646...108,419,495 JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP
ISO
dioscin inhibits the reaction [Ethanol results in decreased expression of GSR protein] CTD PMID:24146112 NCBI chr16:58,482,209...58,525,256 JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions EXP dioscin inhibits the reaction [Doxorubicin results in increased expression of HMGB1 protein]
dioscin inhibited the reaction [thioacetamide increased expression of Hmgb1 protein in liver]
CTD PMID:28082111, PMID:29091898 RGD:15090820 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP dioscin inhibits the reaction [Doxorubicin results in decreased expression of HMOX1 protein]
dioscin inhibited the reaction [thioacetamide decreased expression of Hmox1 protein in liver]
CTD PMID:28082111, PMID:29091898 RGD:15090820 NCBI chr19:13,466,287...13,474,082 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP
ISO
dioscin inhibits the reaction [Ethanol results in increased expression of HSPA5 protein] CTD PMID:24146112 NCBI chr 3:18,055,507...18,059,969 JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP dioscin inhibited the reaction [thioacetamide increased expression of Icam1 protein in liver] RGD PMID:29091898 RGD:15090820 NCBI chr 8:19,553,063...19,565,438 JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP dioscin inhibits the reaction [Doxorubicin results in increased expression of IL1B mRNA]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in increased expression of IL1B mRNA]]
dioscin inhibited the reaction [thioacetamide increased expression of IL-1b mRNA in liver]
CTD PMID:28082111, PMID:29091898 RGD:15090820 NCBI chr 3:116,577,005...116,583,386 JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
dioscin inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]
dioscin inhibited the reaction [thioacetamide increased expression of IL-6 mRNA in liver]
dioscin inhibits the reaction [Doxorubicin results in increased expression of IL6 mRNA]; dioscin inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in increased expression of IL6 mRNA]]
CTD PMID:24146112 PMID:28082111, PMID:29091898 RGD:15090820 NCBI chr 4:5,214,602...5,219,178 JBrowse link
G Kdr kinase insert domain receptor multiple interactions ISO dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of KDR protein] CTD PMID:25111127 NCBI chr14:32,217,871...32,261,018 JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions EXP dioscin inhibits the reaction [Doxorubicin results in increased expression of KEAP1 protein] CTD PMID:28082111 NCBI chr 8:19,768,375...19,777,862 JBrowse link
G Krt18 keratin 18 multiple interactions ISO
EXP
dioscin inhibits the reaction [Acetaminophen results in increased expression of KRT18 protein]; dioscin inhibits the reaction [Ethanol results in increased expression of KRT18 protein] CTD PMID:22939915 PMID:24146112 NCBI chr 7:133,157,486...133,161,162 JBrowse link
G Lrp5 LDL receptor related protein 5 multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [dioscin results in increased expression of LRP5 mRNA]; LRP5 protein affects the reaction [dioscin results in increased expression of TNFRSF11B mRNA]; LRP5 protein affects the reaction [dioscin results in increased expression of TNFSF11 mRNA] CTD PMID:24742230 NCBI chr 1:200,814,247...200,917,581 JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP
ISO
dioscin inhibits the reaction [Ethanol results in increased phosphorylation of MAPK1 protein]
dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of MAPK1 protein]
CTD PMID:24146112 PMID:25111127 NCBI chr11:83,957,813...84,023,629 JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP
ISO
dioscin inhibits the reaction [Ethanol results in increased phosphorylation of MAPK3 protein]
dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of MAPK3 protein]
CTD PMID:24146112 PMID:25111127 NCBI chr 1:181,366,646...181,372,863 JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression ISO dioscin results in increased expression of MAPK8 mRNA CTD PMID:29990575 NCBI chr16:8,638,897...8,721,960 JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases expression ISO dioscin results in increased expression of MAPK9 mRNA CTD PMID:29990575 NCBI chr10:34,169,661...34,211,138 JBrowse link
G Mdh1 malate dehydrogenase 1 multiple interactions ISO dioscin inhibits the reaction [Acetaminophen results in decreased expression of MDH1 protein] CTD PMID:22939915 NCBI chr14:95,630,625...95,645,920 JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases expression ISO dioscin results in decreased expression of MTOR mRNA CTD PMID:29990575 NCBI chr 5:158,884,856...158,994,311 JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP dioscin inhibits the reaction [Doxorubicin results in decreased expression of and affects the localization of NFE2L2 protein]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in decreased expression of NFE2L2 protein]]
dioscin inhibited the reaction [thioacetamide decreased expression of Nfe2L2 protein in liver]
CTD PMID:28082111, PMID:29091898 RGD:15090820 NCBI chr 3:60,594,239...60,621,785 JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP dioscin inhibited the reaction [thioacetamide increased expression of Nfkb1 protein in liver] RGD PMID:29091898 RGD:15090820 NCBI chr 2:224,016,214...224,132,135 JBrowse link
G Nfkbia NFKB inhibitor alpha decreases degradation ISO dioscin results in decreased degradation of NFKBIA protein CTD PMID:24680847 NCBI chr 6:72,858,713...72,861,941 JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP dioscin inhibited the reaction [thioacetamide decreased expression of Nqo1 protein in liver] RGD PMID:29091898 RGD:15090820 NCBI chr19:35,295,633...35,310,528 JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions
increases expression
EXP dioscin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of NR0B2 mRNA]
dioscin results in increased expression of NR0B2 mRNA
CTD PMID:27317372 NCBI chr 5:145,779,294...145,782,609 JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions EXP dioscin inhibits the reaction [Doxorubicin results in decreased expression of NR1H4 protein]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in decreased expression of NFE2L2 protein]]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in increased expression of IL1B mRNA]]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in increased expression of IL6 mRNA]]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in increased expression of RELA protein]]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in increased expression of TNF mRNA]]
dioscin inhibited the reaction [thioacetamide decreased expression of Nr1h4 protein in liver]
CTD PMID:28082111, PMID:29091898 RGD:15090820 NCBI chr 7:23,846,122...23,942,085 JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
decreases expression
increases expression
ISO
EXP
dioscin inhibits the reaction [Ethanol results in increased expression of PARP1 protein]
dioscin results in decreased expression of PARP1 mRNA; dioscin results in decreased expression of PARP1 protein
dioscin results in increased expression of PARP1 mRNA
CTD PMID:24146112 PMID:29990575 PMID:33359023 NCBI chr13:92,307,593...92,339,406 JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta decreases expression ISO dioscin results in decreased expression of PIK3CB mRNA CTD PMID:29990575 NCBI chr 8:99,594,600...99,699,772 JBrowse link
G Pnp purine nucleoside phosphorylase multiple interactions ISO dioscin inhibits the reaction [Acetaminophen results in decreased expression of PNP protein] CTD PMID:22939915 NCBI chr15:24,170,456...24,178,274 JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP
ISO
dioscin inhibits the reaction [Ethanol results in decreased expression of PPARA protein] CTD PMID:24146112 NCBI chr 7:116,832,405...116,900,878 JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions ISO dioscin inhibits the reaction [Acetaminophen results in decreased expression of PRDX1 protein] CTD PMID:22939915 NCBI chr 5:130,147,276...130,162,850 JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions EXP dioscin inhibited the reaction [thioacetamide decreased expression of Prkaa1 protein in liver] RGD PMID:29091898 RGD:15090820 NCBI chr 2:54,240,298...54,275,978 JBrowse link
G Prkab1 protein kinase AMP-activated non-catalytic subunit beta 1 increases expression ISO dioscin results in increased expression of PRKAB1 mRNA CTD PMID:29990575 NCBI chr12:40,588,140...40,598,673 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP dioscin inhibited the reaction [thioacetamide increased expression of Ptgs2 protein in liver] RGD PMID:29091898 RGD:15090820 NCBI chr13:62,164,080...62,169,770 JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of PTK2 protein] CTD PMID:25111127 NCBI chr 7:105,126,725...105,331,848 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP dioscin inhibits the reaction [Doxorubicin results in increased expression of RELA protein]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in increased expression of RELA protein]] CTD PMID:28082111 NCBI chr 1:202,925,001...202,935,484 JBrowse link
G Rgn regucalcin multiple interactions ISO dioscin inhibits the reaction [Acetaminophen results in decreased expression of RGN protein] CTD PMID:22939915 NCBI chr  X:1,619,030...1,634,456 JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases expression ISO dioscin results in decreased expression of RPS6KB1 mRNA CTD PMID:29990575 NCBI chr10:71,323,777...71,367,908 JBrowse link
G Slc10a1 solute carrier family 10 member 1 multiple interactions EXP dioscin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA] CTD PMID:27317372 NCBI chr 6:100,613,045...100,626,670 JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 increases expression EXP dioscin results in increased expression of SLCO1A2 mRNA CTD PMID:27317372 NCBI chr 4:174,710,004...174,764,810 JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 multiple interactions
increases expression
EXP dioscin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLCO1B2 mRNA]; dioscin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLCO1B2 protein]
dioscin results in increased expression of SLCO1B2 mRNA
CTD PMID:27317372 NCBI chr 4:174,551,463...174,619,988 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of SRC protein] CTD PMID:25111127 NCBI chr 3:146,091,969...146,139,492 JBrowse link
G Suox sulfite oxidase multiple interactions ISO dioscin inhibits the reaction [Acetaminophen results in decreased expression of SUOX protein] CTD PMID:22939915 NCBI chr 7:1,103,149...1,107,156 JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO
EXP
dioscin inhibits the reaction [Ethanol results in increased expression of TNF mRNA]
dioscin inhibited the reaction [thioacetamide increased expression of Tnfa mRNA in liver]
dioscin results in increased expression of TNF mRNA; dioscin results in increased expression of TNF protein
dioscin inhibits the reaction [Doxorubicin results in increased expression of TNF mRNA]; dioscin inhibits the reaction [Ethanol results in increased expression of TNF mRNA]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in increased expression of TNF mRNA]]
CTD PMID:22334414 PMID:24146112 PMID:28082111 PMID:29990575 PMID:33359023, PMID:29091898 RGD:15090820 NCBI chr20:3,622,011...3,624,629 JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B increases expression
multiple interactions
ISO dioscin results in increased expression of TNFRSF11B mRNA
fulvestrant inhibits the reaction [dioscin results in increased expression of TNFRSF11B mRNA]; LRP5 protein affects the reaction [dioscin results in increased expression of TNFRSF11B mRNA]
CTD PMID:24742230 NCBI chr 7:85,566,520...85,594,526 JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression ISO dioscin results in increased expression of TNFRSF1A mRNA; dioscin results in increased expression of TNFRSF1A protein CTD PMID:22334414 PMID:29990575 PMID:33359023 NCBI chr 4:158,150,815...158,163,592 JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 increases expression ISO dioscin results in increased expression of TNFRSF25 mRNA CTD PMID:29990575 PMID:33359023 NCBI chr 5:162,621,669...162,626,341 JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases expression
multiple interactions
ISO dioscin results in decreased expression of TNFSF11 mRNA
fulvestrant inhibits the reaction [dioscin results in increased expression of TNFSF11 mRNA]; LRP5 protein affects the reaction [dioscin results in increased expression of TNFSF11 mRNA]
CTD PMID:24742230 NCBI chr15:53,674,990...53,705,171 JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
ISO
EXP
dioscin inhibits the reaction [Acetaminophen results in increased expression of TRP53 protein]; dioscin inhibits the reaction [Ethanol results in increased expression of TRP53 protein]
dioscin results in increased expression of TP53 mRNA; dioscin results in increased expression of TP53 protein
CTD PMID:22334414 PMID:22939915 PMID:24146112 PMID:29990575 NCBI chr10:54,300,070...54,311,525 JBrowse link
G Tradd TNFRSF1A-associated via death domain increases expression ISO dioscin results in increased expression of TRADD mRNA CTD PMID:29990575 PMID:33359023 NCBI chr19:33,136,148...33,142,714 JBrowse link
G Traf1 TNF receptor-associated factor 1 increases expression ISO dioscin results in increased expression of TRAF1 protein CTD PMID:22334414 NCBI chr 3:18,222,024...18,242,163 JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of AKT1 protein]; dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of KDR protein]; dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of MAPK1 protein]; dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of MAPK3 protein]; dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of PTK2 protein]; dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of SRC protein] CTD PMID:25111127 NCBI chr 9:14,955,300...14,970,641 JBrowse link
G Wee1 WEE1 G2 checkpoint kinase increases expression ISO dioscin results in increased expression of WEE1 mRNA CTD PMID:29990575 NCBI chr 1:164,173,681...164,197,688 JBrowse link
ellagic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp3 acid phosphatase 3 increases expression ISO Ellagic Acid results in increased expression of ACP3 mRNA CTD PMID:12002526 NCBI chr 8:104,905,570...104,956,146 JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions ISO Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 protein] CTD PMID:32971123 NCBI chr 8:20,663,984...20,670,604 JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO Ellagic Acid results in increased expression of AIFM1 protein CTD PMID:23554011 NCBI chr  X:127,650,223...127,689,356 JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO Ellagic Acid results in increased phosphorylation of AKT1 protein CTD PMID:26986492 NCBI chr 6:131,713,716...131,735,319 JBrowse link
G Alb albumin multiple interactions
affects binding
ISO ALB protein promotes the reaction [Ellagic Acid results in increased activity of F12 protein]
Ellagic Acid binds to ALB protein
CTD PMID:6343536 PMID:25247703 NCBI chr14:17,607,397...17,622,814 JBrowse link
G Alkbh2 alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase decreases activity ISO Ellagic Acid results in decreased activity of ALKBH2 protein CTD PMID:31088072 NCBI chr12:42,494,187...42,500,929 JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression ISO Ellagic Acid results in decreased expression of APAF1 mRNA CTD PMID:12002526 NCBI chr 7:25,494,143...25,579,540 JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 increases expression ISO Ellagic Acid results in increased expression of ASCL1 mRNA CTD PMID:12002526 NCBI chr 7:21,904,153...21,906,003 JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Ellagic Acid results in increased expression of ASNS mRNA CTD PMID:12002526 NCBI chr 4:35,784,995...35,803,474 JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Ellagic Acid results in increased expression of ATF3 mRNA CTD PMID:12002526 NCBI chr13:102,751,278...102,800,520 JBrowse link
G Atg5 autophagy related 5 increases expression ISO Ellagic Acid results in increased expression of ATG5 mRNA CTD PMID:12002526 NCBI chr20:47,798,222...47,889,216 JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO Ellagic Acid results in increased expression of BAD protein CTD PMID:23554011 NCBI chr 1:204,133,502...204,142,829 JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of BAX mRNA] CTD PMID:29854611 NCBI chr 1:95,940,001...95,945,407 JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
ISO
EXP
Ellagic Acid results in increased expression of BCL2 protein
Ellagic Acid inhibits the reaction [sodium arsenate results in decreased expression of BCL2 mRNA]
[Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 mRNA]
CTD PMID:20103723 PMID:22386815 PMID:29854611 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bmp6 bone morphogenetic protein 6 decreases expression ISO Ellagic Acid results in decreased expression of BMP6 mRNA CTD PMID:12002526 NCBI chr17:26,318,121...26,469,034 JBrowse link
G Brf1 BRF1, RNA polymerase III transcription initiation factor subunit decreases expression ISO Ellagic Acid results in decreased expression of BRF1 mRNA CTD PMID:12002526 NCBI chr 6:132,034,380...132,081,296 JBrowse link
G Calr calreticulin decreases expression ISO Ellagic Acid results in decreased expression of CALR mRNA CTD PMID:12002526 NCBI chr19:23,308,525...23,313,420 JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
increases activity
decreases activity
decreases expression
ISO
EXP
Ellagic Acid results in increased expression of CASP3 mRNA
Ellagic Acid inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased activity of CASP3 protein]
Ellagic Acid results in increased expression of and results in increased activity of CASP3 protein
Ellagic Acid results in increased activity of CASP3 protein
Ellagic Acid results in decreased activity of CASP3 protein
Ellagic Acid results in decreased expression of CASP3 mRNA
CTD PMID:12002526 PMID:22386815 PMID:23554011 PMID:23811531 PMID:28815802 PMID:29854611 NCBI chr16:45,662,910...45,681,171 JBrowse link
G Casp9 caspase 9 multiple interactions ISO Ellagic Acid results in increased expression of and results in increased activity of CASP9 protein CTD PMID:23554011 NCBI chr 5:154,108,872...154,126,628 JBrowse link
G Cat catalase increases activity
multiple interactions
EXP Ellagic Acid results in increased activity of CAT protein
Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; Ellagic Acid inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]
CTD PMID:20074268 PMID:24877639 PMID:29864931 NCBI chr 3:89,842,393...89,874,577 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases secretion ISO Ellagic Acid results in decreased secretion of CCL2 protein CTD PMID:20816778 NCBI chr10:67,005,424...67,007,222 JBrowse link
G Cd14 CD14 molecule decreases expression ISO Ellagic Acid results in decreased expression of CD14 mRNA CTD PMID:20816778 NCBI chr18:28,335,522...28,337,383 JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO Ellagic Acid results in decreased expression of CDK1 protein CTD PMID:23554011 NCBI chr20:19,266,226...19,281,417 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO [resveratrol co-treated with Ellagic Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDKN1A mRNA]
[Ellagic Acid co-treated with Quercetin] results in increased expression of CDKN1A mRNA; Ellagic Acid promotes the reaction [Quercetin results in increased expression of CDKN1A protein]; pifithrin inhibits the reaction [Ellagic Acid promotes the reaction [Quercetin results in increased expression of CDKN1A protein]]
Ellagic Acid results in increased expression of CDKN1A protein
CTD PMID:15735102 PMID:20103723 PMID:23554011 NCBI chr20:7,149,177...7,159,727 JBrowse link
G Ctsd cathepsin D multiple interactions EXP Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:21762681 NCBI chr 1:197,527,467...197,539,343 JBrowse link
G Ctsk cathepsin K multiple interactions ISO Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of CTSK protein] CTD PMID:32971123 NCBI chr 2:183,058,586...183,069,551 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression
decreases activity
ISO Ellagic Acid results in decreased expression of CYP1A1 mRNA
Ellagic Acid results in decreased activity of CYP1A1 protein
CTD PMID:19329757 PMID:20816778 NCBI chr 8:58,096,021...58,102,130 JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity
multiple interactions
ISO Ellagic Acid results in decreased activity of CYP1B1 protein
[Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; [Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]
CTD PMID:19329757 PMID:20103723 NCBI chr 6:15,342,312...15,350,886 JBrowse link
G Daxx death-domain associated protein decreases expression ISO Ellagic Acid results in decreased expression of DAXX mRNA CTD PMID:12002526 NCBI chr20:4,970,090...4,976,145 JBrowse link
G Dffa DNA fragmentation factor subunit alpha decreases expression ISO Ellagic Acid results in decreased expression of DFFA mRNA CTD PMID:12002526 NCBI chr 5:159,540,718...159,553,639 JBrowse link
G E4f1 E4F transcription factor 1 increases expression ISO Ellagic Acid results in increased expression of E4F1 mRNA CTD PMID:12002526 NCBI chr10:13,471,478...13,495,018 JBrowse link
G Egr3 early growth response 3 decreases expression ISO Ellagic Acid results in decreased expression of EGR3 mRNA CTD PMID:12002526 NCBI chr15:45,150,335...45,156,052 JBrowse link
G Endog endonuclease G increases expression ISO Ellagic Acid results in increased expression of ENDOG protein CTD PMID:23554011 NCBI chr 3:13,449,113...13,451,715 JBrowse link
G Ep300 E1A binding protein p300 increases expression ISO Ellagic Acid results in increased expression of EP300 mRNA CTD PMID:12002526 NCBI chr 7:113,108,476...113,178,529 JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 increases expression ISO Ellagic Acid results in increased expression of EPS15 mRNA CTD PMID:12002526 NCBI chr 5:124,045,865...124,146,221 JBrowse link
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit increases expression ISO Ellagic Acid results in increased expression of EZH1 mRNA CTD PMID:12002526 NCBI chr10:86,126,023...86,162,001 JBrowse link
G F12 coagulation factor XII multiple interactions
increases activity
ISO ALB protein promotes the reaction [Ellagic Acid results in increased activity of F12 protein] CTD PMID:6343536 NCBI chr17:9,207,683...9,215,530 JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression ISO Ellagic Acid results in decreased expression of FGFR1 mRNA CTD PMID:12002526 NCBI chr16:66,492,445...66,546,731 JBrowse link
G Flna filamin A decreases expression ISO Ellagic Acid results in decreased expression of FLNA mRNA CTD PMID:12002526 NCBI chr  X:152,007,758...152,034,266 JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein] CTD PMID:24877639 NCBI chr 9:73,196,044...73,264,695 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA]; [Ellagic Acid co-treated with Resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein] CTD PMID:20103723 PMID:32971123 NCBI chr 6:105,121,170...105,124,036 JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity ISO Ellagic Acid results in decreased activity of G6PD protein CTD PMID:25130191 NCBI chr  X:152,201,081...152,220,863 JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions EXP Ellagic Acid inhibits the reaction [phosalone results in increased activity of GAL protein] CTD PMID:27965107 NCBI chr 1:200,650,439...200,655,302 JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 decreases expression ISO Ellagic Acid results in decreased expression of GPLD1 mRNA CTD PMID:12002526 NCBI chr17:40,084,427...40,132,035 JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]; Ellagic Acid inhibits the reaction [sodium arsenite results in increased expression of GPT protein] CTD PMID:24877639 PMID:29935397 NCBI chr 7:108,416,646...108,419,495 JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP Ellagic Acid inhibits the reaction [sodium arsenite results in decreased expression of GPX1 mRNA] CTD PMID:29935397 NCBI chr 8:109,026,905...109,028,031 JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of GSR protein] CTD PMID:24877639 NCBI chr16:58,482,209...58,525,256 JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression ISO Ellagic Acid results in increased expression of GSTA4 mRNA CTD PMID:12002526 NCBI chr 8:79,066,967...79,084,193 JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects expression EXP Ellagic Acid affects the expression of GSTT1 protein CTD PMID:9855024 NCBI chr20:12,856,613...12,873,586 JBrowse link
G Gtf2e2 general transcription factor IIE subunit 2 increases expression ISO Ellagic Acid results in increased expression of GTF2E2 mRNA CTD PMID:12002526 NCBI chr16:58,399,307...58,449,467 JBrowse link
G Gtf2h4 general transcription factor 2H subunit 4 increases expression ISO Ellagic Acid results in increased expression of GTF2H4 mRNA CTD PMID:12002526 NCBI chr20:3,071,328...3,076,990 JBrowse link
G Gusb glucuronidase, beta multiple interactions EXP Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein] CTD PMID:21762681 NCBI chr12:26,701,191...26,714,718 JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression ISO Ellagic Acid results in decreased expression of HIF1A mRNA CTD PMID:12002526 NCBI chr 6:92,624,059...92,669,262 JBrowse link
G Hlcs holocarboxylase synthetase decreases activity ISO Ellagic Acid results in decreased activity of HLCS protein CTD PMID:26303405 NCBI chr11:33,455,806...33,635,197 JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO Ellagic Acid results in increased expression of HMOX1 mRNA; Ellagic Acid results in increased expression of HMOX1 protein
[Paraquat co-treated with Ellagic Acid] results in increased expression of HMOX1 mRNA; [Paraquat co-treated with Ellagic Acid] results in increased expression of HMOX1 protein
CTD PMID:22386815 PMID:23546295 NCBI chr19:13,466,287...13,474,082 JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO [Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene]; [Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene] CTD PMID:20103723 NCBI chr 1:196,290,127...196,299,823 JBrowse link
G Ier2 immediate early response 2 increases expression ISO Ellagic Acid results in increased expression of IER2 mRNA CTD PMID:12002526 NCBI chr19:23,494,551...23,496,075 JBrowse link
G Ifng interferon gamma multiple interactions EXP Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of IFNG mRNA]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of IFNG protein] CTD PMID:29854611 NCBI chr 7:53,903,339...53,907,375 JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression ISO Ellagic Acid results in increased expression of IGFBP2 mRNA CTD PMID:12002526 NCBI chr 9:74,415,574...74,442,945 JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression ISO Ellagic Acid results in decreased expression of IGFBP4 mRNA CTD PMID:12002526 NCBI chr10:83,995,253...84,007,272 JBrowse link
G Il1b interleukin 1 beta decreases expression
multiple interactions
ISO
EXP
Ellagic Acid results in decreased expression of IL1B mRNA
Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of IL1B mRNA]; Ellagic Acid inhibits the reaction [sodium arsenite results in increased expression of IL1B protein]
Ellagic Acid inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein]
CTD PMID:18377686 PMID:20816778 PMID:21762681 PMID:24877639 PMID:27965107 PMID:29455002 PMID:29854611 PMID:29864931 NCBI chr 3:116,577,005...116,583,386 JBrowse link
G Il1r1 interleukin 1 receptor type 1 decreases expression ISO Ellagic Acid results in decreased expression of IL1R1 mRNA CTD PMID:20816778 NCBI chr 9:42,504,917...42,580,958 JBrowse link
G Il6 interleukin 6 multiple interactions EXP Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of IL6 protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL6 mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of IL6 protein] CTD PMID:21762681 PMID:24877639 PMID:27965107 NCBI chr 4:5,214,602...5,219,178 JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D increases expression ISO Ellagic Acid results in increased expression of INPP5D mRNA CTD PMID:12002526 NCBI chr 9:88,287,680...88,392,748 JBrowse link
G Iqgap2 IQ motif containing GTPase activating protein 2 increases expression ISO Ellagic Acid results in increased expression of IQGAP2 mRNA CTD PMID:12002526 NCBI chr 2:26,894,836...27,170,270 JBrowse link
G Irf9 interferon regulatory factor 9 increases expression ISO Ellagic Acid results in increased expression of IRF9 mRNA CTD PMID:12002526 NCBI chr15:29,095,474...29,101,924 JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Ellagic Acid results in decreased expression of JUN mRNA; Ellagic Acid results in decreased expression of JUN protein modified form CTD PMID:23811531 NCBI chr 5:109,894,175...109,897,268 JBrowse link
G Litaf lipopolysaccharide-induced TNF factor increases expression ISO Ellagic Acid results in increased expression of LITAF mRNA CTD PMID:12002526 NCBI chr10:4,656,308...4,692,981 JBrowse link
G Map1a microtubule-associated protein 1A decreases expression ISO Ellagic Acid results in decreased expression of MAP1A mRNA CTD PMID:12002526 NCBI chr 3:108,263,217...108,283,936 JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 decreases expression ISO Ellagic Acid results in decreased expression of MAP3K1 mRNA; Ellagic Acid results in decreased expression of MAP3K1 protein CTD PMID:23811531 NCBI chr 2:43,348,572...43,414,706 JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK1 protein] CTD PMID:32971123 NCBI chr11:83,957,813...84,023,629 JBrowse link
G Mapk11 mitogen-activated protein kinase 11 increases expression ISO Ellagic Acid results in increased expression of MAPK11 mRNA CTD PMID:23811531 NCBI chr 7:120,218,471...120,225,488 JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions EXP Ellagic Acid inhibits the reaction [phosalone results in increased expression of MAPK14 protein] CTD PMID:27965107 NCBI chr20:6,749,646...6,810,590 JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK3 protein] CTD PMID:32971123 NCBI chr 1:181,366,646...181,372,863 JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [Ellagic Acid co-treated with Quercetin] results in increased phosphorylation of MAPK8 protein CTD PMID:15735102 NCBI chr16:8,638,897...8,721,960 JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO [Ellagic Acid co-treated with Quercetin] results in increased phosphorylation of MAPK9 protein CTD PMID:15735102 NCBI chr10:34,169,661...34,211,138 JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 decreases activity EXP Ellagic Acid results in decreased activity of MGST1 protein CTD PMID:16125204 NCBI chr 4:171,029,666...171,044,893 JBrowse link
G Mmd monocyte to macrophage differentiation-associated increases expression ISO Ellagic Acid results in increased expression of MMD mRNA CTD PMID:12002526 NCBI chr10:75,073,278...75,101,528 JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO Ellagic Acid results in decreased activity of and results in decreased secretion of MMP2 protein; zinc chloride inhibits the reaction [Ellagic Acid results in decreased activity of and results in decreased secretion of MMP2 protein] CTD PMID:21573219 NCBI chr19:14,154,657...14,182,870 JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein] CTD PMID:32971123 NCBI chr18:74,046,421...74,156,041 JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects localization
increases expression
multiple interactions
affects response to substance
ISO Ellagic Acid affects the localization of NFE2L2 protein
Ellagic Acid results in increased expression of NFE2L2 mRNA
Ellagic Acid inhibits the reaction [sodium arsenate results in decreased expression of NFE2L2 mRNA]
[Paraquat co-treated with Ellagic Acid] results in increased expression of and affects the localization of NFE2L2 protein; [Paraquat co-treated with Ellagic Acid] results in increased expression of NFE2L2 mRNA; Ellagic Acid results in increased expression of and affects the localization of NFE2L2 protein
Ellagic Acid results in increased expression of NFE2L2 mRNA; Ellagic Acid results in increased expression of NFE2L2 protein
NFE2L2 protein affects the susceptibility to Ellagic Acid
CTD PMID:22386815 PMID:23546295 PMID:30503583 NCBI chr 3:60,594,239...60,621,785 JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 decreases expression ISO Ellagic Acid results in decreased expression of NFKB2 mRNA CTD PMID:12002526 NCBI chr 1:245,164,586...245,173,225 JBrowse link
G Nnat neuronatin increases expression ISO Ellagic Acid results in increased expression of NNAT mRNA CTD PMID:12002526 NCBI chr 3:146,225,941...146,228,868 JBrowse link
G Nop56 NOP56 ribonucleoprotein decreases expression ISO Ellagic Acid results in decreased expression of NOP56 mRNA CTD PMID:12002526 NCBI chr 3:117,476,963...117,481,847 JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP Ellagic Acid inhibits the reaction [Doxorubicin results in increased expression of NOS2 protein] CTD PMID:28815802 NCBI chr10:63,815,308...63,851,208 JBrowse link
G Npas2 neuronal PAS domain protein 2 increases expression ISO Ellagic Acid results in increased expression of NPAS2 mRNA CTD PMID:12002526 NCBI chr 9:41,463,361...41,642,322 JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
ISO Ellagic Acid results in increased expression of NQO1 mRNA; Ellagic Acid results in increased expression of NQO1 protein
[Paraquat co-treated with Ellagic Acid] results in increased expression of NQO1 mRNA; [Paraquat co-treated with Ellagic Acid] results in increased expression of NQO1 protein
CTD PMID:23546295 NCBI chr19:35,295,633...35,310,528 JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO Ellagic Acid results in increased activity of NR1I3 protein CTD PMID:21821919 NCBI chr13:83,632,940...83,638,193 JBrowse link
G Parg poly (ADP-ribose) glycohydrolase decreases activity ISO Ellagic Acid results in decreased activity of PARG protein CTD PMID:19840838 NCBI chr16:7,436,429...7,544,276 JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP Ellagic Acid inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein] CTD PMID:25247703 NCBI chr13:92,307,593...92,339,406 JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO [resveratrol co-treated with Ellagic Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PCNA mRNA] CTD PMID:20103723 NCBI chr 3:119,499,039...119,502,911 JBrowse link
G Pdia2 protein disulfide isomerase family A, member 2 multiple interactions EXP Ellagic Acid inhibits the reaction [Rotenone results in increased nitrosation of and results in decreased activity of PDIA2 protein] CTD PMID:25247703 NCBI chr10:15,215,824...15,218,937 JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity ISO Ellagic Acid results in decreased activity of PGD protein CTD PMID:25130191 NCBI chr 5:159,582,746...159,598,945 JBrowse link
G Pla2g2a phospholipase A2 group IIA decreases expression ISO Ellagic Acid results in decreased expression of PLA2G2A mRNA CTD PMID:20816778 NCBI chr 5:151,076,442...151,079,019 JBrowse link
G Plp2 proteolipid protein 2 increases expression ISO Ellagic Acid results in increased expression of PLP2 mRNA CTD PMID:12002526 NCBI chr  X:14,834,249...14,837,648 JBrowse link
G Pml PML nuclear body scaffold decreases expression ISO Ellagic Acid results in decreased expression of PML mRNA CTD PMID:12002526 NCBI chr 8:58,627,347...58,661,927 JBrowse link
G Ppard peroxisome proliferator-activated receptor delta decreases expression ISO Ellagic Acid results in decreased expression of PPARD mRNA CTD PMID:12002526 NCBI chr20:6,298,785...6,363,970 JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO Ellagic Acid results in increased expression of PPARG protein CTD PMID:23811531 NCBI chr 4:148,423,102...148,548,471 JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions
decreases expression
ISO Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of PPARGC1A mRNA]
Ellagic Acid results in decreased expression of PPARGC1A mRNA
CTD PMID:30503583 NCBI chr14:58,860,752...59,516,525 JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 decreases expression ISO Ellagic Acid results in decreased expression of PRKG1 mRNA CTD PMID:12002526 NCBI chr 1:228,409,883...229,638,794 JBrowse link
G Ptn pleiotrophin decreases expression
increases expression
ISO Ellagic Acid results in decreased expression of PTN mRNA
Ellagic Acid results in increased expression of PTN mRNA
CTD PMID:12002526 NCBI chr 4:65,293,731...65,375,572 JBrowse link
G Ptprn2 protein tyrosine phosphatase, receptor type N2 increases expression ISO Ellagic Acid results in increased expression of PTPRN2 mRNA CTD PMID:12002526 NCBI chr 6:137,439,572...138,191,575 JBrowse link
G Ran RAN, member RAS oncogene family decreases expression ISO Ellagic Acid results in decreased expression of RAN mRNA CTD PMID:12002526 NCBI chr12:27,674,049...27,678,598 JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions EXP Ellagic Acid inhibits the reaction [phosalone results in increased expression of RB1 mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of RB1 protein] CTD PMID:27965107 NCBI chr15:48,371,295...48,502,473 JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs increases expression
multiple interactions
ISO Ellagic Acid results in increased expression of RECK mRNA; Ellagic Acid results in increased expression of RECK protein
zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK mRNA]; zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK protein]
CTD PMID:21573219 NCBI chr 5:58,102,915...58,169,513 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases expression
multiple interactions
ISO
EXP
Ellagic Acid results in decreased expression of RELA mRNA
Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of RELA protein]
Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of RELA protein]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of RELA protein]
CTD PMID:12002526 PMID:24877639 PMID:27965107 PMID:32971123 NCBI chr 1:202,925,001...202,935,484 JBrowse link
G Rgs5 regulator of G-protein signaling 5 decreases expression ISO Ellagic Acid results in decreased expression of RGS5 mRNA CTD PMID:12002526 NCBI chr13:81,848,254...81,885,053 JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO Ellagic Acid results in decreased expression of SCD mRNA CTD PMID:20816778 NCBI chr 1:243,269,745...243,282,878 JBrowse link
G Septin2 septin 2 increases expression ISO Ellagic Acid results in increased expression of SEPTIN2 mRNA CTD PMID:12002526 NCBI chr 9:94,018,141...94,051,386 JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP Ellagic Acid inhibits the reaction [sodium arsenite results in decreased expression of SOD2 mRNA] CTD PMID:29935397 NCBI chr 1:47,638,318...47,645,163 JBrowse link
G Sod3 superoxide dismutase 3 decreases expression ISO Ellagic Acid results in decreased expression of SOD3 mRNA CTD PMID:12002526 NCBI chr14:58,610,104...58,615,845 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of SRC mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of SRC protein] CTD PMID:32971123 NCBI chr 3:146,091,969...146,139,492 JBrowse link
G Star steroidogenic acute regulatory protein increases expression
multiple interactions
ISO Ellagic Acid results in increased expression of STAR mRNA
Ellagic Acid inhibits the reaction [sodium arsenate results in decreased expression of STAR mRNA]
CTD PMID:30503583 NCBI chr16:66,267,094...66,274,368 JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression
decreases expression
ISO Ellagic Acid results in increased expression of STAT3 mRNA
Ellagic Acid results in decreased expression of STAT3 mRNA
CTD PMID:12002526 PMID:20816778 NCBI chr10:85,811,206...85,863,057 JBrowse link
G Taf1c TATA-box binding protein associated factor, RNA polymerase 1 subunit C decreases expression ISO Ellagic Acid results in decreased expression of TAF1C mRNA CTD PMID:12002526 NCBI chr19:47,652,451...47,658,971 JBrowse link
G Tcf12 transcription factor 12 increases expression ISO Ellagic Acid results in increased expression of TCF12 mRNA CTD PMID:12002526 NCBI chr 8:72,490,447...72,799,265 JBrowse link
G Tert telomerase reverse transcriptase multiple interactions
increases expression
ISO
EXP
Ellagic Acid inhibits the reaction [Estradiol results in increased expression of TERT mRNA alternative form]
Ellagic Acid inhibits the reaction [phosalone results in decreased activity of TERT protein]
Ellagic Acid results in increased expression of TERT mRNA alternative form
CTD PMID:19501078 PMID:27965107 NCBI chr 1:29,637,213...29,659,509 JBrowse link
G Tfam transcription factor A, mitochondrial decreases expression ISO Ellagic Acid results in decreased expression of TFAM mRNA CTD PMID:12002526 NCBI chr20:17,356,243...17,368,293 JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
multiple interactions
ISO
EXP
Ellagic Acid results in increased expression of TGFB1 mRNA
Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]
CTD PMID:12002526 PMID:24877639 NCBI chr 1:81,196,532...81,212,848 JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of TNF mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of TNF mRNA]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [sodium arsenite results in increased expression of TNF protein] CTD PMID:21762681 PMID:24877639 PMID:27965107 PMID:28815802 PMID:29455002 PMID:29854611 PMID:29864931 NCBI chr20:3,622,011...3,624,629 JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A multiple interactions
affects binding
ISO Ellagic Acid inhibits the reaction [TNFSF11 protein binds to TNFRSF11A protein]
Ellagic Acid binds to TNFRSF11A protein
CTD PMID:32971123 NCBI chr13:21,928,370...21,986,719 JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions
affects binding
ISO Ellagic Acid inhibits the reaction [TNFSF11 protein binds to TNFRSF11A protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of CTSK protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of SRC mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of SRC protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK1 protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK3 protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of RELA protein]
Ellagic Acid binds to TNFSF11 protein
CTD PMID:32971123 NCBI chr15:53,674,990...53,705,171 JBrowse link
G Tnnt2 troponin T2, cardiac type multiple interactions EXP Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of TNNT2 protein] CTD PMID:21762681 NCBI chr13:47,267,325...47,285,390 JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions
ISO
EXP
Ellagic Acid results in increased expression of TP53 protein
Ellagic Acid promotes the reaction [Quercetin results in increased phosphorylation of TP53 protein]; pifithrin inhibits the reaction [Ellagic Acid promotes the reaction [Quercetin results in increased phosphorylation of TP53 protein]]
Ellagic Acid inhibits the reaction [phosalone results in increased expression of TP53 mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of TP53 protein]
CTD PMID:15735102 PMID:23554011 PMID:27965107 NCBI chr10:54,300,070...54,311,525 JBrowse link
G Ugp2 UDP-glucose pyrophosphorylase 2 decreases expression ISO Ellagic Acid results in decreased expression of UGP2 mRNA CTD PMID:12002526 NCBI chr14:95,456,330...95,497,483 JBrowse link
G Usp4 ubiquitin specific peptidase 4 decreases expression ISO Ellagic Acid results in decreased expression of USP4 mRNA CTD PMID:12002526 NCBI chr 8:109,035,402...109,080,427 JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 increases expression ISO Ellagic Acid results in increased expression of WARS1 mRNA CTD PMID:12002526 NCBI chr 6:127,776,088...127,807,273 JBrowse link
G Wee1 WEE1 G2 checkpoint kinase decreases expression ISO Ellagic Acid results in decreased expression of WEE1 protein CTD PMID:23554011 NCBI chr 1:164,173,681...164,197,688 JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 decreases expression ISO Ellagic Acid results in decreased expression of ZBTB16 mRNA CTD PMID:12002526 NCBI chr 8:48,989,376...49,177,011 JBrowse link
G Zmym2 zinc finger MYM-type containing 2 increases expression ISO Ellagic Acid results in increased expression of ZMYM2 mRNA CTD PMID:12002526 NCBI chr15:31,035,783...31,108,945 JBrowse link
geranic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tyr tyrosinase decreases expression ISO decaprenoic acid results in decreased expression of TYR protein CTD PMID:23286867 NCBI chr 1:141,115,036...141,210,207 JBrowse link
isoliquiritigenin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein affects binding EXP isoliquiritigenin binds to AFP protein CTD PMID:23013281 NCBI chr14:17,573,412...17,591,476 JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene affects the localization of AHR protein] CTD PMID:25110319 NCBI chr 6:52,234,089...52,271,568 JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases response to substance
multiple interactions
decreases phosphorylation
ISO AKT1 protein modified form results in decreased susceptibility to isoliquiritigenin
isoliquiritigenin inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]
20-hydroxyeicosa-5(Z),14(Z)-dienoic acid inhibits the reaction [isoliquiritigenin results in decreased activity of AKT1 protein]; 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid inhibits the reaction [isoliquiritigenin results in decreased phosphorylation of and results in decreased activity of AKT1 protein]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in decreased expression of MMP2 mRNA]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in decreased expression of MMP2 protein]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in decreased expression of MMP9 mRNA]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in decreased expression of MMP9 protein]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP3 protein]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP9 protein]; CAY 10580 inhibits the reaction [isoliquiritigenin results in decreased phosphorylation of and results in decreased activity of AKT1 protein]; Dinoprostone inhibits the reaction [isoliquiritigenin results in decreased activity of AKT1 protein]; Dinoprostone inhibits the reaction [isoliquiritigenin results in decreased phosphorylation of and results in decreased activity of AKT1 protein]; isoliquiritigenin results in decreased phosphorylation of and results in decreased activity of AKT1 protein; Leukotriene B4 inhibits the reaction [isoliquiritigenin results in decreased activity of AKT1 protein]
isoliquiritigenin results in decreased phosphorylation of AKT1 protein
CTD PMID:23747687 PMID:25094029 PMID:27117918 NCBI chr 6:131,713,716...131,735,319 JBrowse link
G Arg1 arginase 1 multiple interactions ISO isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ARG1 mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ARG1 protein] CTD PMID:25026504 NCBI chr 1:20,475,878...20,488,422 JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO isoliquiritigenin results in increased expression of BAX mRNA; isoliquiritigenin results in increased expression of BAX protein CTD PMID:11055382 PMID:27702603 NCBI chr 1:95,940,001...95,945,407 JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases phosphorylation ISO isoliquiritigenin results in decreased phosphorylation of BCL2 protein CTD PMID:23747687 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
decreases phosphorylation
ISO isoliquiritigenin results in decreased expression of BCL2L1 protein
isoliquiritigenin results in decreased phosphorylation of BCL2L1 protein
CTD PMID:11055382 PMID:15729620 PMID:23747687 NCBI chr 3:141,253,508...141,304,582 JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO isoliquiritigenin results in decreased expression of BIRC2 protein CTD PMID:15729620 NCBI chr 8:4,968,856...4,989,325 JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO isoliquiritigenin results in decreased expression of BIRC3 protein CTD PMID:15729620 NCBI chr 8:5,000,844...5,028,470 JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases cleavage
ISO 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP3 protein]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP3 protein]; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP3 protein]; CAY 10580 inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP3 protein]; Dinoprostone inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP3 protein]; isoliquiritigenin results in increased cleavage of and results in increased activity of CASP3 protein
isoliquiritigenin results in increased activity of CASP3 protein
CTD PMID:15729620 PMID:16158945 PMID:23747687 PMID:25094029 NCBI chr16:45,662,910...45,681,171 JBrowse link
G Casp8 caspase 8 increases activity ISO isoliquiritigenin results in increased activity of CASP8 protein CTD PMID:16158945 NCBI chr 9:60,263,863...60,312,542 JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
increases cleavage
ISO 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP9 protein]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP9 protein]; CAY 10580 inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP9 protein]; Dinoprostone inhibits the reaction [isoliquiritigenin results in increased cleavage of CASP9 protein]; isoliquiritigenin results in increased cleavage of and results in increased activity of CASP9 protein
isoliquiritigenin results in increased activity of CASP9 protein
CTD PMID:16158945 PMID:23747687 PMID:25094029 NCBI chr 5:154,108,872...154,126,628 JBrowse link
G Cat catalase multiple interactions EXP isoliquiritigenin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein] CTD PMID:25450236 NCBI chr 3:89,842,393...89,874,577 JBrowse link
G Cckar cholecystokinin A receptor multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [isoliquiritigenin results in increased expression of CCKAR mRNA] CTD PMID:27702603 NCBI chr14:57,292,397...57,300,747 JBrowse link
G Ccnd2 cyclin D2 decreases expression ISO isoliquiritigenin results in decreased expression of CCND2 mRNA CTD PMID:27702603 NCBI chr 4:159,966,883...159,989,261 JBrowse link
G Ccne2 cyclin E2 decreases expression ISO isoliquiritigenin results in decreased expression of CCNE2 mRNA CTD PMID:27702603 NCBI chr 5:24,285,078...24,298,258 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO isoliquiritigenin results in increased expression of CDKN1A mRNA; isoliquiritigenin results in increased expression of CDKN1A protein CTD PMID:27702603 NCBI chr20:7,149,177...7,159,727 JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression ISO isoliquiritigenin results in decreased expression of CDKN1B mRNA CTD PMID:27702603 NCBI chr 4:167,760,067...167,765,177 JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression ISO isoliquiritigenin results in decreased expression of CDKN1C mRNA CTD PMID:27702603 NCBI chr 1:198,655,394...198,658,097 JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO isoliquiritigenin inhibits the reaction [INS1 protein results in increased expression of CEBPA protein] CTD PMID:27117918 NCBI chr 1:87,759,631...87,762,303 JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of CHUK protein] CTD PMID:18295200 NCBI chr 1:242,959,539...242,995,066 JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CXCL10 mRNA] CTD PMID:25026504 NCBI chr14:15,704,772...15,706,969 JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO isoliquiritigenin results in decreased expression of CYP17A1 mRNA CTD PMID:27773742 NCBI chr 1:245,535,462...245,543,148 JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression ISO isoliquiritigenin results in decreased expression of CYP19A1 mRNA CTD PMID:27773742 NCBI chr 8:54,553,165...54,580,758 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]; isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 protein]; isoliquiritigenin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] CTD PMID:25110319 NCBI chr 8:58,096,021...58,102,130 JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
decreases activity
ISO isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A2 mRNA]; isoliquiritigenin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]
isoliquiritigenin results in decreased activity of CYP1A2 protein
CTD PMID:25110319 PMID:29753067 NCBI chr 8:58,075,367...58,082,255 JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
increases expression
ISO isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 protein]; isoliquiritigenin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]; isoliquiritigenin promotes the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of CYP1B1 mRNA]; isoliquiritigenin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
isoliquiritigenin results in increased expression of CYP1B1 mRNA
CTD PMID:25110319 PMID:26134484 NCBI chr 6:15,342,312...15,350,886 JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity ISO isoliquiritigenin results in decreased activity of CYP2C19 protein CTD PMID:29753067 NCBI chr 1:237,938,521...237,976,238 JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP isoliquiritigenin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA]; isoliquiritigenin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein] CTD PMID:25450236 NCBI chr 1:195,840,330...195,850,728 JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO isoliquiritigenin inhibits the reaction [INS1 protein results in increased expression of FABP4 protein] CTD PMID:27117918 NCBI chr 2:91,580,858...91,585,578 JBrowse link
G Gadd45gip1 GADD45G interacting protein 1 increases expression ISO isoliquiritigenin results in increased expression of GADD45GIP1 mRNA CTD PMID:27702603 NCBI chr19:23,320,662...23,323,211 JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO isoliquiritigenin inhibits the reaction [Methamphetamine results in increased expression of GFAP protein] CTD PMID:19834288 NCBI chr10:87,852,891...87,861,631 JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO isoliquiritigenin results in increased expression of HMOX1 protein CTD PMID:23942037 NCBI chr19:13,466,287...13,474,082 JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 decreases expression ISO isoliquiritigenin results in decreased expression of HSD17B1 mRNA CTD PMID:27773742 NCBI chr10:86,009,728...86,011,928 JBrowse link
G Ifng interferon gamma multiple interactions ISO isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IFNG protein]; isoliquiritigenin inhibits the reaction [IFNG protein results in increased abundance of Nitrites]
isoliquiritigenin promotes the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of CYP1B1 mRNA]
CTD PMID:23942037 PMID:25026504 PMID:26134484 NCBI chr 7:53,903,339...53,907,375 JBrowse link
G Il10 interleukin 10 multiple interactions ISO isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL10 protein] CTD PMID:25026504 NCBI chr13:42,472,625...42,477,308 JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions ISO isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL1RN mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL1RN protein] CTD PMID:25026504 NCBI chr 3:7,111,567...7,127,451 JBrowse link
G Il6 interleukin 6 multiple interactions ISO isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL6 mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL6 protein]; isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]; isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein] CTD PMID:18295200 PMID:25026504 NCBI chr 4:5,214,602...5,219,178 JBrowse link
G Insr insulin receptor multiple interactions ISO isoliquiritigenin inhibits the reaction [INS1 protein results in increased phosphorylation of INSR protein] CTD PMID:27117918 NCBI chr12:1,193,193...1,330,976 JBrowse link
G Itgam integrin subunit alpha M multiple interactions
increases expression
ISO TEMPOL-H inhibits the reaction [isoliquiritigenin results in increased expression of ITGAM protein] CTD PMID:24369695 NCBI chr 1:182,659,047...182,709,495 JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein] CTD PMID:18295200 NCBI chr11:83,957,813...84,023,629 JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein] CTD PMID:18295200 NCBI chr 1:181,366,646...181,372,863 JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO isoliquiritigenin results in decreased expression of MKI67 mRNA; isoliquiritigenin results in decreased expression of MKI67 protein CTD PMID:27702603 NCBI chr 1:190,496,319...190,522,983 JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases expression
ISO 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid inhibits the reaction [isoliquiritigenin results in decreased expression of MMP2 mRNA]; 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid inhibits the reaction [isoliquiritigenin results in decreased expression of MMP2 protein]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in decreased expression of MMP2 mRNA]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in decreased expression of MMP2 protein]; CAY 10580 inhibits the reaction [isoliquiritigenin results in decreased expression of MMP2 mRNA]; CAY 10580 inhibits the reaction [isoliquiritigenin results in decreased expression of MMP2 protein]; Dinoprostone inhibits the reaction [isoliquiritigenin results in decreased expression of MMP2 mRNA]; Dinoprostone inhibits the reaction [isoliquiritigenin results in decreased expression of MMP2 protein]
isoliquiritigenin results in decreased expression of MMP2 mRNA; isoliquiritigenin results in decreased expression of MMP2 protein
CTD PMID:25094029 NCBI chr19:14,154,657...14,182,870 JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
ISO 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid inhibits the reaction [isoliquiritigenin results in decreased expression of MMP9 mRNA]; 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid inhibits the reaction [isoliquiritigenin results in decreased expression of MMP9 protein]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in decreased expression of MMP9 mRNA]; AKT1 protein modified form inhibits the reaction [isoliquiritigenin results in decreased expression of MMP9 protein]; CAY 10580 inhibits the reaction [isoliquiritigenin results in decreased expression of MMP9 mRNA]; CAY 10580 inhibits the reaction [isoliquiritigenin results in decreased expression of MMP9 protein]; Dinoprostone inhibits the reaction [isoliquiritigenin results in decreased expression of MMP9 mRNA]; Dinoprostone inhibits the reaction [isoliquiritigenin results in decreased expression of MMP9 protein]
isoliquiritigenin results in decreased expression of MMP9 mRNA; isoliquiritigenin results in decreased expression of MMP9 protein
CTD PMID:25094029 NCBI chr 3:153,684,158...153,692,118 JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions ISO isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MRC1 mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MRC1 protein] CTD PMID:25026504 NCBI chr17:77,249,187...77,330,857 JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of NFKB1 protein] CTD PMID:18295200 NCBI chr 2:224,016,214...224,132,135 JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression
multiple interactions
decreases phosphorylation
ISO isoliquiritigenin results in increased expression of NFKBIA protein
isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased degradation of and results in increased phosphorylation of NFKBIA protein]
isoliquiritigenin results in decreased phosphorylation of NFKBIA protein
CTD PMID:15729620 PMID:18295200 NCBI chr 6:72,858,713...72,861,941 JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NOS2 mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NOS2 protein]; isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein]; isoliquiritigenin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; isoliquiritigenin inhibits the reaction [Methamphetamine results in increased expression of NOS2 protein] CTD PMID:18295200 PMID:19834288 PMID:25026504 PMID:26134484 NCBI chr10:63,815,308...63,851,208 JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO isoliquiritigenin results in increased expression of NQO1 protein CTD PMID:26473469 NCBI chr19:35,295,633...35,310,528 JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
increases expression
ISO isoliquiritigenin results in increased activity of NR1I2 protein
isoliquiritigenin results in increased expression of NR1I2 mRNA
CTD PMID:29933105 NCBI chr11:62,460,213...62,496,665 JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO isoliquiritigenin results in increased cleavage of PARP1 protein
benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [isoliquiritigenin results in increased cleavage of PARP1 protein]
CTD PMID:23747687 NCBI chr13:92,307,593...92,339,406 JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 decreases phosphorylation ISO isoliquiritigenin results in decreased phosphorylation of PDK1 protein CTD PMID:25094029 NCBI chr 3:56,705,824...56,733,040 JBrowse link
G Pla2g5 phospholipase A2, group V decreases expression ISO isoliquiritigenin results in decreased expression of PLA2G5 mRNA CTD PMID:23747687 NCBI chr 5:151,041,339...151,109,433 JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO isoliquiritigenin inhibits the reaction [INS1 protein results in increased expression of PPARG protein] CTD PMID:27117918 NCBI chr 4:148,423,102...148,548,471 JBrowse link
G Ptger4 prostaglandin E receptor 4 decreases expression ISO isoliquiritigenin results in decreased expression of PTGER4 mRNA; isoliquiritigenin results in decreased expression of PTGER4 protein CTD PMID:25094029 NCBI chr 2:54,330,563...54,347,451 JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO isoliquiritigenin results in decreased expression of PTGS1 mRNA CTD PMID:25094029 NCBI chr 3:19,584,015...19,605,589 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions
ISO
EXP
isoliquiritigenin results in decreased expression of PTGS2 mRNA
isoliquiritigenin inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein]
isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PTGS2 mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PTGS2 protein]; isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 mRNA]; isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein]
CTD PMID:18295200 PMID:23747687 PMID:25026504 PMID:25450236 NCBI chr13:62,164,080...62,169,770 JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 multiple interactions ISO isoliquiritigenin inhibits the reaction [INS1 protein results in decreased activity of and results in increased oxidation of PTPN1 protein] CTD PMID:27117918 NCBI chr 3:156,638,811...156,687,503 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit affects localization
multiple interactions
decreases activity
ISO isoliquiritigenin affects the localization of RELA protein
isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of RELA protein]
isoliquiritigenin results in decreased activity of RELA protein
CTD PMID:15729620 PMID:18295200 NCBI chr 1:202,925,001...202,935,484 JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions
decreases activity
ISO isoliquiritigenin inhibits the reaction [SLC2A1 protein affects the transport of Glucose]
isoliquiritigenin results in decreased activity of SLC2A1 protein
CTD PMID:14642735 NCBI chr 5:132,717,196...132,745,416 JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions ISO isoliquiritigenin inhibits the reaction [INS1 protein results in increased expression of SLC2A4 protein] CTD PMID:27117918 NCBI chr10:54,666,015...54,671,581 JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions ISO isoliquiritigenin inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein] CTD PMID:19834288 NCBI chr 1:29,709,443...29,750,413 JBrowse link
G Slco1a1 solute carrier organic anion transporter family, member 1a1 multiple interactions
decreases activity
EXP [isoliquiritigenin results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Bosentan; [isoliquiritigenin results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Methotrexate CTD PMID:32259555 NCBI chr 4:174,877,045...174,950,857 JBrowse link
G Sod2 superoxide dismutase 2 affects response to substance ISO SOD2 protein affects the susceptibility to isoliquiritigenin CTD PMID:23526725 NCBI chr 1:47,638,318...47,645,163 JBrowse link
G Star steroidogenic acute regulatory protein increases expression ISO isoliquiritigenin results in increased expression of STAR mRNA CTD PMID:27773742 NCBI chr16:66,267,094...66,274,368 JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased phosphorylation of STAT3 protein] CTD PMID:25026504 NCBI chr10:85,811,206...85,863,057 JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TGFB1 protein] CTD PMID:25026504 NCBI chr 1:81,196,532...81,212,848 JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TNF protein]; isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]; isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]
isoliquiritigenin promotes the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of CYP1B1 mRNA]
isoliquiritigenin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]
CTD PMID:18295200 PMID:25026504 PMID:25450236 PMID:26134484 NCBI chr20:3,622,011...3,624,629 JBrowse link
G Tp53 tumor protein p53 increases expression ISO isoliquiritigenin results in increased expression of TRP53 mRNA CTD PMID:27702603 NCBI chr10:54,300,070...54,311,525 JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of isoliquiritigenin CTD PMID:14557274 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of isoliquiritigenin CTD PMID:14557274 NCBI chr 9:88,727,094...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of isoliquiritigenin CTD PMID:14557274 NCBI chr 9:88,696,981...88,808,465 JBrowse link
isorhamnetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases transport
increases expression
ISO ABCB1 protein results in increased transport of 3-methylquercetin
3-methylquercetin results in increased expression of ABCB1 mRNA
CTD PMID:15969930 PMID:26238175 NCBI chr 4:25,357,467...25,529,941 JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity ISO 3-methylquercetin results in decreased activity of ABCC1 protein CTD PMID:15670588 NCBI chr10:528,961...655,179 JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO 3-methylquercetin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; 3-methylquercetin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]
3-methylquercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]; 3-methylquercetin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; 3-methylquercetin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]
CTD PMID:27151496 NCBI chr 1:231,746,527...231,759,307 JBrowse link
G Agt angiotensinogen multiple interactions EXP 3-methylquercetin inhibits the reaction [AGT protein results in increased expression of NCF1 protein] CTD PMID:17374653 NCBI chr19:52,529,139...52,549,618 JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO 3-methylquercetin inhibits the reaction [Benzo(a)pyrene results in increased activity of AHR protein] CTD PMID:19794518 NCBI chr 6:52,234,089...52,271,568 JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions
ISO
EXP
3-methylquercetin results in decreased phosphorylation of AKT1 protein
3-methylquercetin affects the reaction [Hydrogen Peroxide results in increased phosphorylation of AKT1 protein]
CTD PMID:12826665 PMID:19222219 NCBI chr 6:131,713,716...131,735,319 JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO 3-methylquercetin results in decreased expression of BCL2 mRNA; 3-methylquercetin results in decreased expression of BCL2 protein CTD PMID:22992727 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO 3-methylquercetin results in decreased expression of BCL2L1 mRNA; 3-methylquercetin results in decreased expression of BCL2L1 protein CTD PMID:22992727 NCBI chr 3:141,253,508...141,304,582 JBrowse link
G Casp3 caspase 3 decreases expression
multiple interactions
increases activity
ISO
EXP
3-methylquercetin results in decreased expression of CASP3 protein
3-methylquercetin inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]
3-methylquercetin results in increased activity of CASP3 protein
CTD PMID:12826665 PMID:19222219 PMID:22992727 NCBI chr16:45,662,910...45,681,171 JBrowse link
G Casp9 caspase 9 decreases expression ISO 3-methylquercetin results in decreased expression of CASP9 protein CTD PMID:22992727 NCBI chr 5:154,108,872...154,126,628 JBrowse link
G Cat catalase multiple interactions EXP 3-methylquercetin inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein]; [quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of CAT mRNA; [quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of CAT protein CTD PMID:19222219 PMID:25716194 NCBI chr 3:89,842,393...89,874,577 JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [3-methylquercetin co-treated with Lipopolysaccharides] affects the expression of CCL3 mRNA CTD PMID:20579867 NCBI chr10:68,451,388...68,452,938 JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO 3-methylquercetin results in decreased expression of CCND1 mRNA; 3-methylquercetin results in decreased expression of CCND1 protein CTD PMID:22992727 NCBI chr 1:200,089,002...200,098,524 JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO 3-methylquercetin inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] CTD PMID:27151496 NCBI chr10:79,883,622...79,900,625 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO 3-methylquercetin inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A1 protein]; [Quercetin co-treated with kaempferol co-treated with 3-methylquercetin co-treated with ginkgolide A co-treated with ginkgolide B co-treated with ginkgolide C co-treated with ginkgolide J co-treated with bilobalide] affects the activity of CYP1A1 protein; [Quercetin co-treated with kaempferol co-treated with 3-methylquercetin co-treated with ginkgolide A co-treated with ginkgolide B co-treated with ginkgolide C co-treated with ginkgolide J co-treated with bilobalide] inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A1 protein]; [Quercetin co-treated with kaempferol co-treated with 3-methylquercetin co-treated with ginkgolide A co-treated with ginkgolide B co-treated with ginkgolide C co-treated with ginkgolide J co-treated with bilobalide] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; [Quercetin co-treated with kaempferol co-treated with 3-methylquercetin] affects the activity of CYP1A1 protein; [Quercetin co-treated with kaempferol co-treated with 3-methylquercetin] inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A1 protein]; [Quercetin co-treated with kaempferol co-treated with 3-methylquercetin] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] CTD PMID:21329749 NCBI chr 8:58,096,021...58,102,130 JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases expression ISO 3-methylquercetin results in decreased expression of CYP1B1 mRNA CTD PMID:19794518 NCBI chr 6:15,342,312...15,350,886 JBrowse link
G Edn1 endothelin 1 multiple interactions EXP 3-methylquercetin inhibits the reaction [EDN1 protein results in increased expression of NCF1 mRNA]; 3-methylquercetin inhibits the reaction [EDN1 protein results in increased expression of NCF1 protein] CTD PMID:18436224 NCBI chr17:22,454,924...22,460,812 JBrowse link
G Esr1 estrogen receptor 1 affects binding ISO 3-methylquercetin binds to ESR1 protein CTD PMID:14706564 NCBI chr 1:41,106,335...41,499,104 JBrowse link
G Esr2 estrogen receptor 2 affects binding ISO 3-methylquercetin binds to ESR2 protein CTD PMID:14706564 NCBI chr 6:94,858,438...94,909,630 JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
increases expression
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[3-methylquercetin results in increased activity of NFE2L2 protein] which results in increased expression of GCLC protein]; [3-methylquercetin affects the localization of and results in increased activity of NFE2L2 protein] which results in increased expression of GCLC protein; dorsomorphin inhibits the reaction [[3-methylquercetin results in increased activity of NFE2L2 protein] which results in increased expression of GCLC protein]; rottlerin inhibits the reaction [[3-methylquercetin results in increased activity of NFE2L2 protein] which results in increased expression of GCLC protein]
[quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of GCLC mRNA; [quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of GCLC protein
3-methylquercetin results in increased expression of GCLC mRNA; 3-methylquercetin results in increased expression of GCLC protein
CTD PMID:24211276 PMID:25716194 NCBI chr 8:78,629,899...78,668,547 JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO 3-methylquercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of GPT protein] CTD PMID:27151496 NCBI chr 7:108,416,646...108,419,495 JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[3-methylquercetin results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 protein]; [3-methylquercetin affects the localization of and results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 protein; dorsomorphin inhibits the reaction [[3-methylquercetin results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 protein]; rottlerin inhibits the reaction [[3-methylquercetin results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 protein]
[quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of HMOX1 mRNA; [quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of HMOX1 protein
3-methylquercetin results in increased expression of HMOX1 mRNA; 3-methylquercetin results in increased expression of HMOX1 protein
3-methylquercetin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of HMOX1 mRNA]; [3-methylquercetin results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 protein
CTD PMID:24211276 PMID:24337631 PMID:25716194 PMID:27151496 NCBI chr19:13,466,287...13,474,082 JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
3-methylquercetin inhibits the reaction [Carrageenan results in increased expression of IL1B protein]
3-methylquercetin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein]; 3-methylquercetin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; [3-methylquercetin co-treated with Lipopolysaccharides] affects the expression of IL1B mRNA
CTD PMID:20579867 PMID:23774260 NCBI chr 3:116,577,005...116,583,386 JBrowse link
G Il6 interleukin 6 multiple interactions EXP
ISO
3-methylquercetin inhibits the reaction [Carrageenan results in increased expression of IL6 protein]
3-methylquercetin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein]; 3-methylquercetin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; [3-methylquercetin co-treated with Lipopolysaccharides] affects the expression of IL6 mRNA
CTD PMID:20579867 PMID:23774260 NCBI chr 4:5,214,602...5,219,178 JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP 3-methylquercetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:19222219 NCBI chr16:8,638,897...8,721,960 JBrowse link
G Mir155 microRNA 155 multiple interactions ISO 3-methylquercetin inhibits the reaction [Lipopolysaccharides results in increased expression of MIR155 mRNA] CTD PMID:20579867 NCBI chr11:23,774,654...23,774,718 JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions EXP 3-methylquercetin inhibits the reaction [AGT protein results in increased expression of NCF1 protein]; 3-methylquercetin inhibits the reaction [EDN1 protein results in increased expression of NCF1 mRNA]; 3-methylquercetin inhibits the reaction [EDN1 protein results in increased expression of NCF1 protein] CTD PMID:17374653 PMID:18436224 NCBI chr12:22,485,382...22,494,647 JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects response to substance
multiple interactions
affects localization
increases activity
ISO NFE2L2 protein affects the susceptibility to 3-methylquercetin
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[3-methylquercetin results in increased activity of NFE2L2 protein] which results in increased expression of GCLC protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[3-methylquercetin results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 protein]; 3-methylquercetin affects the localization of and results in increased phosphorylation of and results in increased activity of NFE2L2 protein; [3-methylquercetin affects the localization of and results in increased activity of NFE2L2 protein] which results in increased abundance of Glutathione; [3-methylquercetin affects the localization of and results in increased activity of NFE2L2 protein] which results in increased expression of GCLC protein; [3-methylquercetin affects the localization of and results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 protein; [3-methylquercetin affects the localization of and results in increased activity of NFE2L2 protein] which results in increased expression of NQO1 mRNA; [3-methylquercetin affects the localization of and results in increased activity of NFE2L2 protein] which results in increased expression of SESN2 mRNA; dorsomorphin inhibits the reaction [[3-methylquercetin results in increased activity of NFE2L2 protein] which results in increased expression of GCLC protein]; dorsomorphin inhibits the reaction [[3-methylquercetin results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [3-methylquercetin inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NFE2L2 protein affects the reaction [3-methylquercetin inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]]; rottlerin inhibits the reaction [[3-methylquercetin results in increased activity of NFE2L2 protein] which results in increased expression of GCLC protein]; rottlerin inhibits the reaction [[3-methylquercetin results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 protein]
3-methylquercetin affects the localization of NFE2L2 protein
[3-methylquercetin results in increased activity of NFE2L2 protein] which results in increased expression of GCLC protein; [3-methylquercetin results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 protein; NFE2L2 protein affects the reaction [3-methylquercetin results in decreased susceptibility to tert-Butylhydroperoxide]
CTD PMID:24211276 PMID:27151496 NCBI chr 3:60,594,239...60,621,785 JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO 3-methylquercetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased degradation of NFKBIA protein] CTD PMID:23774260 NCBI chr 6:72,858,713...72,861,941 JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO 3-methylquercetin inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; 3-methylquercetin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of NOS2 protein]; 3-methylquercetin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; 3-methylquercetin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; [3-methylquercetin co-treated with Lipopolysaccharides] affects the expression of NOS2 mRNA CTD PMID:16213685 PMID:18178435 PMID:18274639 PMID:20579867 PMID:23774260 NCBI chr10:63,815,308...63,851,208 JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO 3-methylquercetin inhibits the reaction [Lipids results in decreased expression of NOS3] CTD PMID:16891912 NCBI chr 4:10,793,834...10,814,170 JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [3-methylquercetin affects the localization of and results in increased activity of NFE2L2 protein] which results in increased expression of NQO1 mRNA CTD PMID:24211276 NCBI chr19:35,295,633...35,310,528 JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO 3-methylquercetin binds to and results in increased activity of NR1I2 protein
3-methylquercetin results in increased activity of NR1I2 protein
CTD PMID:26238175 NCBI chr11:62,460,213...62,496,665 JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 multiple interactions ISO 3-methylquercetin inhibits the reaction [Lipids results in increased expression of OLR1] CTD PMID:16891912 NCBI chr 4:162,926,436...162,949,057 JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO 3-methylquercetin results in increased cleavage of PARP1 protein CTD PMID:22992727 NCBI chr13:92,307,593...92,339,406 JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 decreases expression ISO 3-methylquercetin results in decreased expression of PECAM1 protein CTD PMID:22992727 NCBI chr10:91,590,521...91,652,279 JBrowse link
G Pon1 paraoxonase 1 increases expression ISO 3-methylquercetin results in increased expression of PON1 mRNA CTD PMID:20228421 NCBI chr 4:33,294,737...33,325,759 JBrowse link
G Pon2 paraoxonase 2 increases expression ISO 3-methylquercetin results in increased expression of PON2 mRNA CTD PMID:19865538 NCBI chr 4:33,389,702...33,425,186 JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases activity ISO 3-methylquercetin results in increased activity of PPARD protein CTD PMID:22992727 NCBI chr20:6,298,785...6,363,970 JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases expression
ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [3-methylquercetin results in increased activity of PPARG protein]; 3-methylquercetin binds to and results in increased activity of PPARG protein
3-methylquercetin results in increased expression of PPARG protein
CTD PMID:22992727 NCBI chr 4:148,423,102...148,548,471 JBrowse link
G Prkcd protein kinase C, delta increases phosphorylation ISO 3-methylquercetin results in increased phosphorylation of PRKCD protein CTD PMID:24211276 NCBI chr16:5,769,226...5,807,214 JBrowse link
G Ptges prostaglandin E synthase multiple interactions ISO 3-methylquercetin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGES mRNA] CTD PMID:21341175 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases activity
ISO
EXP
3-methylquercetin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 mRNA]; 3-methylquercetin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein]; 3-methylquercetin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; 3-methylquercetin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; 3-methylquercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Acetylcysteine promotes the reaction [3-methylquercetin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein]]; tin protoporphyrin IX inhibits the reaction [3-methylquercetin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein]]
3-methylquercetin results in decreased activity of PTGS2 protein
3-methylquercetin inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein]
CTD PMID:15292928 PMID:21341175 PMID:24337631 NCBI chr13:62,164,080...62,169,770 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO 3-methylquercetin inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of RELA protein]; 3-methylquercetin inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:18274639 PMID:20579867 PMID:23774260 NCBI chr 1:202,925,001...202,935,484 JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO 3-methylquercetin inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; 3-methylquercetin inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 protein]; NFE2L2 protein affects the reaction [3-methylquercetin inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]
3-methylquercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of SERPINE1 protein]; 3-methylquercetin inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; 3-methylquercetin inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 protein]
CTD PMID:27151496 NCBI chr12:19,601,272...19,611,657 JBrowse link
G Sesn2 sestrin 2 multiple interactions ISO [3-methylquercetin affects the localization of and results in increased activity of NFE2L2 protein] which results in increased expression of SESN2 mRNA CTD PMID:24211276 NCBI chr 5:144,702,287...144,721,241 JBrowse link
G Smad2 SMAD family member 2 multiple interactions ISO 3-methylquercetin inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein] CTD PMID:27151496 NCBI chr18:69,849,884...69,918,926 JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO 3-methylquercetin inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]; NFE2L2 protein affects the reaction [3-methylquercetin inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]] CTD PMID:27151496 NCBI chr 8:64,126,829...64,236,960 JBrowse link
G Tff1 trefoil factor 1 increases expression ISO 3-methylquercetin results in increased expression of TFF1 mRNA CTD PMID:14706564 NCBI chr20:9,235,736...9,239,597 JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO 3-methylquercetin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; 3-methylquercetin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; 3-methylquercetin inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; 3-methylquercetin inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; 3-methylquercetin inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 protein]; 3-methylquercetin inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein]; 3-methylquercetin inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]; NFE2L2 protein affects the reaction [3-methylquercetin inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NFE2L2 protein affects the reaction [3-methylquercetin inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]] CTD PMID:27151496 NCBI chr 1:81,196,532...81,212,848 JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
3-methylquercetin inhibits the reaction [Carrageenan results in increased expression of TNF protein]
3-methylquercetin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]; 3-methylquercetin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; 3-methylquercetin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
CTD PMID:20579867 PMID:23774260 NCBI chr20:3,622,011...3,624,629 JBrowse link
G Tyr tyrosinase increases expression ISO 3-methylquercetin results in increased expression of TYR protein CTD PMID:24853321 NCBI chr 1:141,115,036...141,210,207 JBrowse link
G Tyrp1 tyrosinase-related protein 1 increases expression ISO 3-methylquercetin results in increased expression of TYRP1 protein CTD PMID:24853321 NCBI chr 5:95,280,982...95,299,516 JBrowse link
kojic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca13 ATP binding cassette subfamily A member 13 decreases expression ISO kojic acid results in decreased expression of ABCA13 mRNA CTD PMID:16595896 NCBI chr14:83,873,397...84,376,138 JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of ABCC2 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in decreased expression of ABCC2 mRNA CTD PMID:18544905 NCBI chr 1:242,664,657...242,723,239 JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 multiple interactions ISO
EXP
[Diethylnitrosamine co-treated with kojic acid] results in increased expression of ABCC6 mRNA
[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of ABCC6 mRNA
CTD PMID:17917374 PMID:18544905 NCBI chr 1:96,447,224...96,501,464 JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid] results in increased expression of ABCC9 mRNA CTD PMID:17917374 NCBI chr 4:175,531,854...175,655,849 JBrowse link
G Abcd1 ATP binding cassette subfamily D member 1 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid] results in increased expression of ABCD1 mRNA CTD PMID:17917374 NCBI chr  X:151,428,334...151,450,115 JBrowse link
G Abcf2 ATP binding cassette subfamily F member 2 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid] results in increased expression of ABCF2 mRNA CTD PMID:17917374 NCBI chr 4:10,594,802...10,607,606 JBrowse link
G Abhd1 abhydrolase domain containing 1 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid] results in decreased expression of ABHD1 mRNA CTD PMID:17917374 NCBI chr 6:25,422,526...25,427,514 JBrowse link
G Acer3 alkaline ceramidase 3 increases expression ISO kojic acid results in increased expression of ACER3 mRNA CTD PMID:16595896 NCBI chr 1:152,504,180...152,606,596 JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase decreases expression ISO kojic acid results in decreased expression of ACMSD mRNA CTD PMID:16595896 NCBI chr13:39,200,486...39,244,337 JBrowse link
G Acvrl1 activin A receptor like type 1 decreases expression ISO kojic acid results in decreased expression of ACVRL1 mRNA CTD PMID:16595896 NCBI chr 7:132,239,200...132,256,592 JBrowse link
G Adam20 ADAM metallopeptidase domain 20 decreases expression ISO kojic acid results in decreased expression of ADAM20 mRNA CTD PMID:16595896
G Adrb3 adrenoceptor beta 3 decreases expression ISO kojic acid results in decreased expression of ADRB3 mRNA CTD PMID:16595896 NCBI chr16:64,839,820...64,844,552 JBrowse link
G Agap3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 increases expression ISO kojic acid results in increased expression of AGAP3 mRNA CTD PMID:16595896 NCBI chr 4:10,674,064...10,724,848 JBrowse link
G Agbl4 AGBL carboxypeptidase 4 decreases expression ISO kojic acid results in decreased expression of AGBL4 mRNA CTD PMID:16595896 NCBI chr 5:125,254,963...126,534,367 JBrowse link
G Ahnak AHNAK nucleoprotein decreases expression ISO kojic acid results in decreased expression of AHNAK mRNA CTD PMID:16595896 NCBI chr 1:205,882,223...205,970,934 JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression ISO kojic acid results in decreased expression of AKT1 mRNA CTD PMID:16595896 NCBI chr 6:131,713,716...131,735,319 JBrowse link
G Alpi alkaline phosphatase, intestinal decreases expression ISO kojic acid results in decreased expression of ALPI mRNA CTD PMID:16595896 NCBI chr 9:87,773,411...87,776,877 JBrowse link
G Amtn amelotin decreases expression ISO kojic acid results in decreased expression of AMTN mRNA CTD PMID:16595896 NCBI chr14:19,648,624...19,661,181 JBrowse link
G Anxa1 annexin A1 decreases expression ISO kojic acid results in decreased expression of ANXA1 mRNA CTD PMID:16595896 NCBI chr 1:217,861,175...217,877,205 JBrowse link
G Anxa5 annexin A5 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ANXA5 mRNA CTD PMID:17917374 NCBI chr 2:119,314,007...119,344,703 JBrowse link
G Ap1s1 adaptor related protein complex 1 subunit sigma 1 decreases expression ISO kojic acid results in decreased expression of AP1S1 mRNA CTD PMID:16595896 NCBI chr12:19,625,267...19,635,792 JBrowse link
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 decreases expression ISO kojic acid results in decreased expression of APOBEC1 mRNA CTD PMID:16595896 NCBI chr 4:155,800,030...155,828,515 JBrowse link
G App amyloid beta precursor protein increases expression ISO kojic acid results in increased expression of APP mRNA CTD PMID:16595896 NCBI chr11:24,019,774...24,236,584 JBrowse link
G Aptx aprataxin decreases expression ISO kojic acid results in decreased expression of APTX mRNA CTD PMID:16595896 NCBI chr 5:55,798,896...55,822,963 JBrowse link
G Aqp1 aquaporin 1 increases expression ISO kojic acid results in increased expression of AQP1 mRNA CTD PMID:16595896 NCBI chr 4:84,482,512...84,494,690 JBrowse link
G Arfip2 ADP-ribosylation factor interacting protein 2 decreases expression ISO kojic acid results in decreased expression of ARFIP2 mRNA CTD PMID:16595896 NCBI chr 1:159,974,255...159,980,398 JBrowse link
G Arhgef16 Rho guanine nucleotide exchange factor 16 decreases expression ISO kojic acid results in decreased expression of ARHGEF16 mRNA CTD PMID:16595896 NCBI chr 5:164,843,656...164,866,212 JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 increases expression ISO kojic acid results in increased expression of ARL6IP5 mRNA CTD PMID:16595896 NCBI chr 4:129,810,650...129,838,628 JBrowse link
G Asnsd1 asparagine synthetase domain containing 1 decreases expression ISO kojic acid results in decreased expression of ASNSD1 mRNA CTD PMID:16595896 NCBI chr 9:48,126,802...48,139,073 JBrowse link
G Atf6b activating transcription factor 6 beta decreases expression ISO kojic acid results in decreased expression of ATF6B mRNA CTD PMID:16595896 NCBI chr20:4,090,921...4,098,920 JBrowse link
G Atm ATM serine/threonine kinase multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ATM mRNA CTD PMID:17917374 NCBI chr 8:53,828,741...53,932,773 JBrowse link
G B4galnt4 beta-1,4-N-acetyl-galactosaminyl transferase 4 decreases expression ISO kojic acid results in decreased expression of B4GALNT4 mRNA CTD PMID:16595896 NCBI chr 1:196,171,394...196,182,294 JBrowse link
G Bag5 BAG cochaperone 5 decreases expression ISO kojic acid results in decreased expression of BAG5 mRNA CTD PMID:16595896 NCBI chr 6:130,768,467...130,772,122 JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO kojic acid results in increased expression of BCL2A1 mRNA CTD PMID:16595896 NCBI chr 8:89,716,914...89,724,998 JBrowse link
G Bcl2l2 Bcl2-like 2 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of BCL2L2 mRNA CTD PMID:17917374 NCBI chr15:28,346,449...28,361,627 JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO kojic acid results in decreased expression of BIRC2 mRNA CTD PMID:16595896 NCBI chr 8:4,968,856...4,989,325 JBrowse link
G Bmp5 bone morphogenetic protein 5 decreases expression ISO kojic acid results in decreased expression of BMP5 mRNA CTD PMID:16595896 NCBI chr 8:76,517,164...76,639,925 JBrowse link
G Brsk1 BR serine/threonine kinase 1 decreases expression ISO kojic acid results in decreased expression of BRSK1 mRNA CTD PMID:16595896 NCBI chr 1:69,134,166...69,159,947 JBrowse link
G Bst2 bone marrow stromal cell antigen 2 decreases expression ISO kojic acid results in decreased expression of BST2 mRNA CTD PMID:16595896 NCBI chr16:18,217,404...18,220,979 JBrowse link
G C2H1orf54 chromosome 2 C1orf54 homolog increases expression ISO kojic acid results in increased expression of C1ORF54 mRNA CTD PMID:16595896 NCBI chr 2:183,424,989...183,434,773 JBrowse link
G Ca13 carbonic anhydrase 13 increases expression ISO kojic acid results in increased expression of CAR13 mRNA CTD PMID:19000923 NCBI chr 2:86,928,401...86,959,525 JBrowse link
G Ca14 carbonic anhydrase 14 increases expression ISO kojic acid results in increased expression of CA14 mRNA CTD PMID:16595896 NCBI chr 2:183,442,263...183,449,207 JBrowse link
G Cab39l calcium binding protein 39-like increases expression ISO kojic acid results in increased expression of CAB39L mRNA CTD PMID:16595896 NCBI chr15:33,606,588...33,710,518 JBrowse link
G Calr calreticulin multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CALR mRNA CTD PMID:18544905 NCBI chr19:23,308,525...23,313,420 JBrowse link
G Casp4 caspase 4 multiple interactions EXP [kojic acid co-treated with Diethylnitrosamine] results in increased expression of CASP4 mRNA; Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of CASP4 mRNA] CTD PMID:18544905 NCBI chr 8:2,599,017...2,635,097 JBrowse link
G Casp8 caspase 8 multiple interactions EXP [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CASP8 mRNA CTD PMID:18544905 NCBI chr 9:60,263,863...60,312,542 JBrowse link
G Cat catalase multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CAT mRNA CTD PMID:18544905 NCBI chr 3:89,842,393...89,874,577 JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 increases expression ISO kojic acid results in increased expression of CCAR1 mRNA CTD PMID:16595896 NCBI chr20:30,685,916...30,728,531 JBrowse link
G Ccdc50 coiled-coil domain containing 50 increases expression ISO kojic acid results in increased expression of CCDC50 mRNA CTD PMID:16595896 NCBI chr11:73,332,798...73,395,333 JBrowse link
G Ccl21 C-C motif chemokine ligand 21 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCL21A mRNA CTD PMID:17917374 NCBI chr 5:56,980,557...56,981,661 JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCL3 mRNA CTD PMID:17917374 NCBI chr10:68,451,388...68,452,938 JBrowse link
G Ccnb1 cyclin B1 increases expression ISO kojic acid results in increased expression of CCNB1 mRNA CTD PMID:19000923 NCBI chr 2:31,912,190...31,921,163 JBrowse link
G Ccnc cyclin C multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCNC mRNA CTD PMID:17917374 NCBI chr 5:35,266,828...35,284,943 JBrowse link
G Ccnd1 cyclin D1 multiple interactions EXP
ISO
[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of CCND1 mRNA
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCND1 mRNA
CTD PMID:17917374 PMID:18544905 NCBI chr 1:200,089,002...200,098,524 JBrowse link
G Ccng1 cyclin G1 multiple interactions EXP
ISO
[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of CCNG1 mRNA
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCNG1 mRNA
CTD PMID:17917374 PMID:18544905 NCBI chr10:25,176,231...25,182,604 JBrowse link
G Ccpg1 cell cycle progression 1 decreases expression ISO kojic acid results in decreased expression of CCPG1 mRNA CTD PMID:16595896 NCBI chr 8:73,719,960...73,752,437 JBrowse link
G Ccr4 C-C motif chemokine receptor 4 decreases expression ISO kojic acid results in decreased expression of CCR4 mRNA CTD PMID:16595896 NCBI chr 8:114,176,256...114,182,155 JBrowse link
G Cd22 CD22 molecule decreases expression ISO kojic acid results in decreased expression of CD22 mRNA CTD PMID:16595896 NCBI chr 1:86,116,376...86,132,782 JBrowse link
G Cd274 CD274 molecule increases expression ISO kojic acid results in increased expression of CD274 mRNA CTD PMID:16595896 NCBI chr 1:227,116,627...227,137,379 JBrowse link
G Cd3g CD3g molecule decreases expression ISO kojic acid results in decreased expression of CD3G mRNA CTD PMID:16595896 NCBI chr 8:45,280,797...45,287,271 JBrowse link
G Cdin1 CDAN1 interacting nuclease 1 increases expression ISO kojic acid results in increased expression of CDIN1 mRNA CTD PMID:16595896 NCBI chr 3:102,441,553...102,646,935 JBrowse link
G Cdk10 cyclin-dependent kinase 10 decreases expression ISO kojic acid results in decreased expression of CDK10 mRNA CTD PMID:16595896 NCBI chr19:51,260,012...51,273,009 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO
EXP
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CDKN1A mRNA
[Diethylnitrosamine co-treated with kojic acid] results in increased expression of CDKN1A mRNA
CTD PMID:17917374 PMID:18544905 NCBI chr20:7,149,177...7,159,727 JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions EXP [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CDKN1B mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CDKN1B mRNA CTD PMID:18544905 NCBI chr 4:167,760,067...167,765,177 JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 decreases expression ISO kojic acid results in decreased expression of CEACAM1 mRNA CTD PMID:16595896 NCBI chr 1:81,043,595...81,060,050 JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO kojic acid results in increased expression of CEBPD mRNA CTD PMID:16595896 NCBI chr11:84,764,670...84,765,808 JBrowse link
G Cenpq centromere protein Q decreases expression ISO kojic acid results in decreased expression of CENPQ mRNA CTD PMID:16595896 NCBI chr 9:19,957,040...19,972,807 JBrowse link
G Cep192 centrosomal protein 192 increases expression ISO kojic acid results in increased expression of CEP192 mRNA CTD PMID:16595896 NCBI chr18:61,346,957...61,458,405 JBrowse link
G Cep72 centrosomal protein 72 increases expression ISO kojic acid results in increased expression of CEP72 mRNA CTD PMID:16595896 NCBI chr 1:29,225,312...29,255,294 JBrowse link
G Ces1d carboxylesterase 1D multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CES1 mRNA CTD PMID:18544905 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions EXP [kojic acid co-treated with Diethylnitrosamine] results in increased expression of CHEK2 mRNA; Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of CHEK2 mRNA] CTD PMID:18544905 NCBI chr12:45,788,823...45,821,382 JBrowse link
G Chst4 carbohydrate sulfotransferase 4 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid] results in decreased expression of CHST4 mRNA CTD PMID:17917374 NCBI chr19:37,993,471...38,002,123 JBrowse link
G Cibar1 CBY1 interacting BAR domain containing 1 increases expression ISO kojic acid results in increased expression of CIBAR1 mRNA CTD PMID:16595896 NCBI chr 5:25,613,993...25,632,440 JBrowse link
G Cldn3 claudin 3 decreases expression ISO kojic acid results in decreased expression of CLDN3 mRNA CTD PMID:16595896 NCBI chr12:21,708,538...21,710,010 JBrowse link
G Cldnd2 claudin domain containing 2 decreases expression ISO kojic acid results in decreased expression of CLDND2 mRNA CTD PMID:16595896 NCBI chr 1:93,848,533...93,851,693 JBrowse link
G Clec4b2 C-type lectin domain family 4, member B2 decreases expression ISO kojic acid results in decreased expression of CLEC4C mRNA CTD PMID:16595896 NCBI chr 4:156,462,742...156,486,240 JBrowse link
G Clmp CXADR-like membrane protein decreases expression ISO kojic acid results in decreased expression of CLMP mRNA CTD PMID:16595896 NCBI chr 8:41,060,527...41,168,841 JBrowse link
G Clu clusterin multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CLU mRNA CTD PMID:18544905 NCBI chr15:40,161,068...40,200,315 JBrowse link
G Cnih1 cornichon family AMPA receptor auxiliary protein 1 increases expression ISO kojic acid results in increased expression of CNIH1 mRNA CTD PMID:16595896 NCBI chr15:20,037,885...20,049,857 JBrowse link
G Cnksr2 connector enhancer of kinase suppressor of Ras 2 decreases expression ISO kojic acid results in decreased expression of CNKSR2 mRNA CTD PMID:16595896 NCBI chr  X:36,908,135...37,148,337 JBrowse link
G Col17a1 collagen type XVII alpha 1 chain decreases expression ISO kojic acid results in decreased expression of COL17A1 mRNA CTD PMID:16595896 NCBI chr 1:246,530,589...246,577,632 JBrowse link
G Col24a1 collagen type XXIV alpha 1 chain decreases expression ISO kojic acid results in decreased expression of COL24A1 mRNA CTD PMID:16595896 NCBI chr 2:234,212,256...234,469,445 JBrowse link
G Colq collagen like tail subunit of asymmetric acetylcholinesterase increases expression ISO kojic acid results in increased expression of COLQ mRNA CTD PMID:16595896 NCBI chr16:6,731,850...6,824,973 JBrowse link
G Comt catechol-O-methyltransferase multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of COMT mRNA CTD PMID:18544905 NCBI chr11:82,568,052...82,587,642 JBrowse link
G Cops2 COP9 signalosome subunit 2 decreases expression ISO kojic acid results in decreased expression of COPS2 mRNA CTD PMID:16595896 NCBI chr 3:113,084,174...113,110,090 JBrowse link
G Coq10a coenzyme Q10A increases expression ISO kojic acid results in increased expression of COQ10A mRNA CTD PMID:16595896 NCBI chr 7:792,089...798,392 JBrowse link
G Coq8a coenzyme Q8A increases expression ISO kojic acid results in increased expression of COQ8A mRNA CTD PMID:16595896 NCBI chr13:91,904,731...91,933,588 JBrowse link
G Cpb1 carboxypeptidase B1 decreases expression ISO kojic acid results in decreased expression of CPB1 mRNA CTD PMID:16595896 NCBI chr 2:102,755,241...102,785,628 JBrowse link
G Cpe carboxypeptidase E increases expression ISO kojic acid results in increased expression of CPE mRNA CTD PMID:16595896 NCBI chr16:25,030,276...25,142,231 JBrowse link
G Cpne5 copine 5 increases expression ISO kojic acid results in increased expression of CPNE5 mRNA CTD PMID:16595896 NCBI chr20:7,206,742...7,289,309 JBrowse link
G Creb1 cAMP responsive element binding protein 1 decreases phosphorylation ISO kojic acid results in decreased phosphorylation of CREB1 protein CTD PMID:27586645 NCBI chr 9:65,903,511...65,972,562 JBrowse link
G Cse1l chromosome segregation 1 like decreases expression ISO kojic acid results in decreased expression of CSE1L mRNA CTD PMID:16595896 NCBI chr 3:155,641,104...155,678,866 JBrowse link
G Ctnnal1 catenin alpha-like 1 decreases expression ISO kojic acid results in decreased expression of CTNNAL1 mRNA CTD PMID:16595896 NCBI chr 5:71,514,340...71,569,431 JBrowse link
G Ctsz cathepsin Z increases expression ISO kojic acid results in increased expression of CTSZ mRNA CTD PMID:16595896 NCBI chr 3:163,224,875...163,235,645 JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYB5R3 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CYB5R3 mRNA CTD PMID:18544905 NCBI chr 7:114,306,686...114,324,247 JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 increases expression ISO kojic acid results in increased expression of CYP26B1 mRNA CTD PMID:16595896 NCBI chr 4:117,041,808...117,058,628 JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP2A5 mRNA CTD PMID:17917374 NCBI chr 1:82,171,914...82,179,980 JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP2B10 mRNA CTD PMID:17917374 NCBI chr 1:81,518,387...81,544,999 JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2B15 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CYP2B15 mRNA CTD PMID:18544905 NCBI chr 1:82,094,188...82,106,492 JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP2B9 mRNA CTD PMID:17917374 NCBI chr 1:81,652,762...81,732,153 JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2C mRNA CTD PMID:18544905 NCBI chr 1:236,762,719...236,799,069 JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2C13 mRNA CTD PMID:18544905 NCBI chr 1:238,786,764...238,867,195 JBrowse link
G Cyp2c7 cytochrome P450, family 2, subfamily c, polypeptide 7 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2C7 mRNA CTD PMID:18544905 NCBI chr 1:237,332,641...237,388,714 JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2D22 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CYP2D22 mRNA CTD PMID:18544905 NCBI chr 7:113,882,584...113,891,754 JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2E1 mRNA CTD PMID:18544905 NCBI chr 1:195,840,330...195,850,728 JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2F2 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CYP2F2 mRNA CTD PMID:18544905 NCBI chr 1:82,416,108...82,429,897 JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP4A22 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CYP4A22 mRNA CTD PMID:18544905 NCBI chr 5:129,123,323...129,137,464 JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 multiple interactions ISO
EXP
[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of CYP4B1 mRNA
[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP4B1 mRNA
CTD PMID:17917374 PMID:18544905 NCBI chr 5:129,139,019...129,176,860 JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP7A1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CYP7A1 mRNA CTD PMID:17917374 NCBI chr 5:19,376,979...19,386,676 JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP8B1 mRNA CTD PMID:18544905 NCBI chr 8:121,578,123...121,580,093 JBrowse link
G Cyth3 cytohesin 3 increases expression ISO kojic acid results in increased expression of CYTH3 mRNA CTD PMID:16595896 NCBI chr12:10,840,137...10,933,792 JBrowse link
G Cytip cytohesin 1 interacting protein increases expression ISO kojic acid results in increased expression of CYTIP mRNA CTD PMID:16595896 NCBI chr 3:42,698,058...42,774,955 JBrowse link
G Dagla diacylglycerol lipase, alpha increases expression ISO kojic acid results in increased expression of DAGLA mRNA CTD PMID:16595896 NCBI chr 1:206,890,635...206,947,332 JBrowse link
G Dazap2 DAZ associated protein 2 increases expression ISO kojic acid results in increased expression of DAZAP2 mRNA CTD PMID:16595896 NCBI chr 7:131,714,723...131,720,266 JBrowse link
G Dcaf13 DDB1 and CUL4 associated factor 13 decreases expression ISO kojic acid results in decreased expression of DCAF13 mRNA CTD PMID:16595896 NCBI chr 7:70,160,983...70,196,142 JBrowse link
G Dct dopachrome tautomerase decreases expression ISO kojic acid results in decreased expression of DCT protein CTD PMID:27586645 NCBI chr15:95,062,006...95,100,863 JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions EXP [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of DDIT3 mRNA CTD PMID:18544905 NCBI chr 7:63,115,645...63,121,203 JBrowse link
G Dek DEK proto-oncogene decreases expression ISO kojic acid results in decreased expression of DEK mRNA CTD PMID:16595896 NCBI chr17:17,580,804...17,602,825 JBrowse link
G Dlgap4 DLG associated protein 4 increases expression ISO kojic acid results in increased expression of DLGAP4 mRNA CTD PMID:16595896 NCBI chr 3:145,124,189...145,271,791 JBrowse link
G Dlx1 distal-less homeobox 1 decreases expression ISO kojic acid results in decreased expression of DLX1 mRNA CTD PMID:16595896 NCBI chr 3:56,356,190...56,360,780 JBrowse link
G Dmxl1 Dmx-like 1 decreases expression ISO kojic acid results in decreased expression of DMXL1 mRNA CTD PMID:16595896 NCBI chr18:42,993,292...43,163,457 JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of DNAJA1 mRNA CTD PMID:18544905 NCBI chr 5:55,842,414...55,853,326 JBrowse link
G Dnaja2 DnaJ heat shock protein family (Hsp40) member A2 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of DNAJA2 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of DNAJA2 mRNA CTD PMID:18544905 NCBI chr19:21,497,792...21,516,904 JBrowse link
G Dnttip2 deoxynucleotidyltransferase, terminal, interacting protein 2 decreases expression ISO kojic acid results in decreased expression of DNTTIP2 mRNA CTD PMID:16595896 NCBI chr 2:210,374,240...210,386,366 JBrowse link
G Dock4 dedicator of cytokinesis 4 increases expression ISO kojic acid results in increased expression of DOCK4 mRNA CTD PMID:16595896 NCBI chr 6:57,512,929...57,902,597 JBrowse link
G Dok4 docking protein 4 decreases expression ISO kojic acid results in decreased expression of DOK4 mRNA CTD PMID:16595896 NCBI chr19:10,146,520...10,157,187 JBrowse link
G Dpyd dihydropyrimidine dehydrogenase multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid] results in increased expression of DPYD mRNA CTD PMID:18544905 NCBI chr 2:206,609,043...207,474,982 JBrowse link
G Dspp dentin sialophosphoprotein decreases expression ISO kojic acid results in decreased expression of DSPP mRNA CTD PMID:16595896 NCBI chr14:5,565,562...5,571,669 JBrowse link
G Dstn destrin, actin depolymerizing factor increases expression ISO kojic acid results in increased expression of DSTN mRNA CTD PMID:16595896 NCBI chr 3:131,284,647...131,311,361 JBrowse link
G Dynlt3 dynein light chain Tctex-type 3 decreases expression ISO kojic acid results in decreased expression of DYNLT3 mRNA CTD PMID:16595896 NCBI chr  X:13,327,933...13,337,139 JBrowse link
G E2f3 E2F transcription factor 3 increases expression ISO kojic acid results in increased expression of E2F3 mRNA CTD PMID:16595896 NCBI chr17:34,601,756...34,679,139 JBrowse link
G E2f8 E2F transcription factor 8 increases expression ISO kojic acid results in increased expression of E2F8 mRNA CTD PMID:16595896 NCBI chr 1:98,565,717...98,584,265 JBrowse link
G Efna3 ephrin A3 decreases expression ISO kojic acid results in decreased expression of EFNA3 mRNA CTD PMID:16595896 NCBI chr 2:174,729,192...174,738,111 JBrowse link
G Egr1 early growth response 1 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of EGR1 mRNA CTD PMID:18544905 NCBI chr18:26,463,333...26,465,531 JBrowse link
G Eif4e eukaryotic translation initiation factor 4E decreases expression ISO kojic acid results in decreased expression of EIF4E mRNA CTD PMID:16595896 NCBI chr 2:227,066,519...227,099,261 JBrowse link
G Eif5a2 eukaryotic translation initiation factor 5A2 increases expression ISO kojic acid results in increased expression of EIF5A2 mRNA CTD PMID:16595896 NCBI chr 2:111,728,587...111,746,087 JBrowse link
G Elane elastase, neutrophil expressed decreases expression ISO kojic acid results in decreased expression of ELANE mRNA CTD PMID:16595896 NCBI chr 7:9,817,251...9,819,174 JBrowse link
G Ep300 E1A binding protein p300 increases expression ISO kojic acid results in increased expression of EP300 mRNA CTD PMID:16595896 NCBI chr 7:113,108,476...113,178,529 JBrowse link
G Epha10 EPH receptor A10 decreases expression ISO kojic acid results in decreased expression of EPHA10 mRNA CTD PMID:16595896 NCBI chr 5:137,139,588...137,175,637 JBrowse link
G Epha4 Eph receptor A4 increases expression ISO kojic acid results in increased expression of EPHA4 mRNA CTD PMID:16595896 NCBI chr 9:78,815,460...78,958,139 JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of EPHX1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of EPHX1 mRNA CTD PMID:18544905 NCBI chr13:92,714,315...92,744,124 JBrowse link
G Ephx2 epoxide hydrolase 2 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of EPHX2 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of EPHX2 mRNA CTD PMID:18544905 NCBI chr15:40,289,901...40,327,632 JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC2 mRNA CTD PMID:17917374 NCBI chr 1:79,033,342...79,047,102 JBrowse link
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of ERCC3 mRNA CTD PMID:18544905 NCBI chr18:23,883,613...23,914,326 JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC4 mRNA CTD PMID:17917374 NCBI chr10:2,416,259...2,448,364 JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC5 mRNA CTD PMID:17917374 NCBI chr 9:46,309,477...46,354,478 JBrowse link
G Esam endothelial cell adhesion molecule increases expression ISO kojic acid results in increased expression of ESAM mRNA CTD PMID:16595896 NCBI chr 8:37,238,228...37,249,217 JBrowse link
G Esrp1 epithelial splicing regulatory protein 1 increases expression ISO kojic acid results in increased expression of ESRP1 mRNA CTD PMID:16595896 NCBI chr 5:24,427,611...24,482,157 JBrowse link
G Exd1 exonuclease 3'-5' domain containing 1 decreases expression ISO kojic acid results in decreased expression of EXD1 mRNA CTD PMID:16595896 NCBI chr 3:106,507,839...106,535,922 JBrowse link
G Exoc2 exocyst complex component 2 increases expression ISO kojic acid results in increased expression of EXOC2 mRNA CTD PMID:16595896 NCBI chr17:33,506,289...33,698,246 JBrowse link
G F10 coagulation factor X increases expression ISO kojic acid results in increased expression of F10 mRNA CTD PMID:16595896 NCBI chr16:76,468,834...76,488,141 JBrowse link
G Fam241a family with sequence similarity 241 member A increases expression ISO kojic acid results in increased expression of FAM241A mRNA CTD PMID:16595896 NCBI chr 2:216,344,563...216,375,193 JBrowse link
G Fbn2 fibrillin 2 increases expression ISO kojic acid results in increased expression of FBN2 mRNA CTD PMID:16595896 NCBI chr18:51,499,737...51,703,976 JBrowse link
G Fbxo16 F-box protein 16 increases expression ISO kojic acid results in increased expression of FBXO16 mRNA CTD PMID:16595896 NCBI chr15:39,492,268...39,541,493 JBrowse link
G Fgf12 fibroblast growth factor 12 increases expression ISO kojic acid results in increased expression of FGF12 mRNA CTD PMID:16595896 NCBI chr11:71,997,049...72,564,965 JBrowse link
G Fgf5 fibroblast growth factor 5 decreases expression ISO kojic acid results in decreased expression of FGF5 mRNA CTD PMID:16595896 NCBI chr14:11,325,334...11,346,570 JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 decreases expression ISO kojic acid results in decreased expression of FGFR3 mRNA CTD PMID:16595896 NCBI chr14:76,987,242...77,002,671 JBrowse link
G Fibcd1 fibrinogen C domain containing 1 decreases expression ISO kojic acid results in decreased expression of FIBCD1 mRNA CTD PMID:16595896 NCBI chr 3:15,092,681...15,126,399 JBrowse link
G Fkbp10 FKBP prolyl isomerase 10 increases expression ISO kojic acid results in increased expression of FKBP10 mRNA CTD PMID:16595896 NCBI chr10:85,345,434...85,357,998 JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of FMO1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of FMO1 mRNA CTD PMID:18544905 NCBI chr13:75,182,184...75,214,439 JBrowse link
G Fpgt fucose-1-phosphate guanylyltransferase decreases expression ISO kojic acid results in decreased expression of FPGT mRNA CTD PMID:16595896 NCBI chr 2:244,099,031...244,119,967 JBrowse link
G Frmpd4 FERM and PDZ domain containing 4 decreases expression ISO kojic acid results in decreased expression of FRMPD4 mRNA CTD PMID:16595896 NCBI chr  X:25,853,849...26,814,642 JBrowse link
G Fzd8 frizzled class receptor 8 increases expression ISO kojic acid results in increased expression of FZD8 mRNA CTD PMID:16595896 NCBI chr17:57,312,924...57,320,551 JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta multiple interactions EXP [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GADD45B mRNA CTD PMID:18544905 NCBI chr 7:8,778,004...8,780,306 JBrowse link
G Galnt1 polypeptide N-acetylgalactosaminyltransferase 1 decreases expression ISO kojic acid results in decreased expression of GALNT1 mRNA CTD PMID:16595896 NCBI chr18:15,489,015...15,568,849 JBrowse link
G Gfod1 glucose-fructose oxidoreductase domain containing 1 decreases expression ISO kojic acid results in decreased expression of GFOD1 mRNA CTD PMID:16595896 NCBI chr17:21,400,142...21,504,972 JBrowse link
G Gle1 GLE1 RNA export mediator decreases expression ISO kojic acid results in decreased expression of GLE1 mRNA CTD PMID:16595896 NCBI chr 3:13,209,312...13,237,018 JBrowse link
G Gmpr guanosine monophosphate reductase decreases expression ISO kojic acid results in decreased expression of GMPR mRNA CTD PMID:16595896 NCBI chr17:19,151,820...19,189,626 JBrowse link
G Gnb1 G protein subunit beta 1 increases expression ISO kojic acid results in increased expression of GNB1 mRNA CTD PMID:16595896 NCBI chr 5:166,075,508...166,142,223 JBrowse link
G Gpr146 G protein-coupled receptor 146 decreases expression ISO kojic acid results in decreased expression of GPR146 mRNA CTD PMID:16595896 NCBI chr12:15,251,936...15,267,217 JBrowse link
G Gpr26 G protein-coupled receptor 26 decreases expression ISO kojic acid results in decreased expression of GPR26 mRNA CTD PMID:16595896 NCBI chr 1:186,766,001...186,805,435 JBrowse link
G Gpr32 G protein-coupled receptor 32 increases expression ISO kojic acid results in increased expression of GPR32 mRNA CTD PMID:16595896 NCBI chr 1:94,756,863...94,757,895 JBrowse link
G Gpr61 G protein-coupled receptor 61 decreases expression ISO kojic acid results in decreased expression of GPR61 mRNA CTD PMID:16595896 NCBI chr 2:195,781,931...195,789,798 JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GPX1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of GPX1 mRNA CTD PMID:18544905 NCBI chr 8:109,026,905...109,028,031 JBrowse link
G Gsdma gasdermin A decreases expression ISO kojic acid results in decreased expression of GSDMA mRNA CTD PMID:16595896 NCBI chr10:83,614,336...83,639,543 JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of GSR mRNA CTD PMID:17917374 NCBI chr16:58,482,209...58,525,256 JBrowse link
G Gsta2 glutathione S-transferase alpha 2 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTA2 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTA2 mRNA CTD PMID:18544905 NCBI chr 8:79,184,535...79,196,827 JBrowse link
G Gsta4 glutathione S-transferase alpha 4 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTA4 mRNA CTD PMID:18544905 NCBI chr 8:79,066,967...79,084,193 JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTM1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM1 mRNA CTD PMID:18544905 NCBI chr 2:195,649,845...195,655,402 JBrowse link
G Gstm2 glutathione S-transferase mu 2 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTM2 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM2 mRNA CTD PMID:18544905 NCBI chr 2:195,624,015...195,628,774 JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions ISO
EXP
[Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM3 mRNA
[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTM3 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM3 mRNA
CTD PMID:17917374 PMID:18544905 NCBI chr 2:195,531,627...195,534,562 JBrowse link
G Gucy1a2 guanylate cyclase 1 soluble subunit alpha 2 decreases expression ISO kojic acid results in decreased expression of GUCY1A2 mRNA CTD PMID:16595896 NCBI chr 8:500,212...900,201 JBrowse link
G H1f1 H1.1 linker histone, cluster member increases expression ISO kojic acid results in increased expression of H1-1 mRNA CTD PMID:16595896 NCBI chr17:41,366,268...41,367,011 JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 increases expression ISO kojic acid results in increased expression of HAND1 mRNA CTD PMID:16595896 NCBI chr10:42,006,646...42,009,213 JBrowse link
G Harbi1 harbinger transposase derived 1 decreases expression ISO kojic acid results in decreased expression of HARBI1 mRNA CTD PMID:16595896 NCBI chr 3:77,681,431...77,689,749 JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase decreases expression ISO kojic acid results in decreased expression of HIBCH mRNA CTD PMID:16595896 NCBI chr 9:48,590,097...48,669,896 JBrowse link
G Hint3 histidine triad nucleotide binding protein 3 increases expression ISO kojic acid results in increased expression of HINT3 mRNA CTD PMID:16595896 NCBI chr 1:27,035,936...27,045,799 JBrowse link
G Hip1 huntingtin interacting protein 1 increases expression ISO kojic acid results in increased expression of HIP1 mRNA CTD PMID:16595896 NCBI chr12:21,133,319...21,267,796 JBrowse link
G Hlf HLF transcription factor, PAR bZIP family member decreases expression ISO kojic acid results in decreased expression of HLF mRNA CTD PMID:16595896 NCBI chr10:75,154,244...75,211,884 JBrowse link
G Hmmr hyaluronan-mediated motility receptor decreases expression ISO kojic acid results in decreased expression of HMMR mRNA CTD PMID:16595896 NCBI chr10:25,132,933...25,163,029 JBrowse link
G Hmox2 heme oxygenase 2 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HMOX2 mRNA CTD PMID:18544905 NCBI chr10:10,797,076...10,831,178 JBrowse link
G Hnrnph2 heterogeneous nuclear ribonucleoprotein H2 increases expression ISO kojic acid results in increased expression of HNRNPH2 mRNA CTD PMID:16595896 NCBI chr  X:97,780,890...97,786,846 JBrowse link
G Hps3 HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 decreases expression ISO kojic acid results in decreased expression of HPS3 mRNA CTD PMID:16595896 NCBI chr 2:102,484,574...102,527,580 JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSP90AA1 mRNA CTD PMID:18544905 NCBI chr 6:129,702,376...129,707,907 JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSP90AB1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of HSP90AB1 mRNA CTD PMID:18544905 NCBI chr 9:15,432,986...15,438,358 JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSPA1A mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of HSPA1A mRNA CTD PMID:18544905
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSPA5 mRNA CTD PMID:18544905 NCBI chr 3:18,055,507...18,059,969 JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSPB1 mRNA CTD PMID:18544905 NCBI chr12:20,794,014...20,795,675 JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSPD1 mRNA CTD PMID:18544905 NCBI chr 9:56,579,195...56,590,011 JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 multiple interactions EXP
ISO
[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSPE1 mRNA
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of HSPE1 mRNA
CTD PMID:17917374 PMID:18544905 NCBI chr 9:56,589,912...56,593,000 JBrowse link
G Hyou1 hypoxia up-regulated 1 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HYOU1 mRNA CTD PMID:18544905 NCBI chr 8:44,706,073...44,718,189 JBrowse link
G Igf2r insulin-like growth factor 2 receptor multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of IGF2R mRNA CTD PMID:18544905 NCBI chr 1:47,979,109...48,067,501 JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid] results in decreased expression of IL1A mRNA CTD PMID:18544905 NCBI chr 3:116,526,601...116,537,055 JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid] results in decreased expression of IL1B mRNA CTD PMID:18544905 NCBI chr 3:116,577,005...116,583,386 JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression ISO kojic acid results in increased expression of IL1RL1 mRNA CTD PMID:19000923 NCBI chr 9:42,661,694...42,727,266 JBrowse link
G Il22ra1 interleukin 22 receptor subunit alpha 1 increases expression ISO kojic acid results in increased expression of IL22RA1 mRNA CTD PMID:16595896 NCBI chr 5:147,961,496...147,986,296 JBrowse link
G Il6 interleukin 6 decreases expression ISO kojic acid results in decreased expression of IL6 protein CTD PMID:12727023 NCBI chr 4:5,214,602...5,219,178 JBrowse link
G Il6st interleukin 6 cytokine family signal transducer decreases expression ISO kojic acid results in decreased expression of IL6ST mRNA CTD PMID:16595896 NCBI chr 2:44,065,979...44,106,255 JBrowse link
G Incenp inner centromere protein increases expression ISO kojic acid results in increased expression of INCENP mRNA CTD PMID:16595896 NCBI chr 1:206,520,655...206,550,575 JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO kojic acid results in increased expression of JUN mRNA CTD PMID:19000923 NCBI chr 5:109,894,175...109,897,268 JBrowse link
G Kars lysyl-tRNA synthetase decreases expression ISO kojic acid results in decreased expression of KARS1 mRNA CTD PMID:16595896 NCBI chr19:39,957,846...39,976,886 JBrowse link
G Kcnab3 potassium voltage-gated channel subfamily A regulatory beta subunit 3 decreases expression ISO kojic acid results in decreased expression of KCNAB3 mRNA CTD PMID:16595896 NCBI chr10:54,047,830...54,056,401 JBrowse link
G Kctd17 potassium channel tetramerization domain containing 17 decreases expression ISO kojic acid results in decreased expression of KCTD17 mRNA CTD PMID:16595896 NCBI chr 7:109,979,060...110,009,091 JBrowse link
G Kdm4d lysine demethylase 4D increases expression ISO kojic acid results in increased expression of KDM4D mRNA CTD PMID:16595896 NCBI chr 8:11,279,756...11,304,920 JBrowse link
G Klf5 Kruppel-like factor 5 increases expression ISO kojic acid results in increased expression of KLF5 mRNA CTD PMID:16595896 NCBI chr15:76,060,320...76,079,445 JBrowse link
G Klhl13 kelch-like family member 13 increases expression ISO kojic acid results in increased expression of KLHL13 mRNA CTD PMID:16595896 NCBI chr  X:113,942,309...114,107,355 JBrowse link
G Klkb1 kallikrein B1 decreases expression ISO kojic acid results in decreased expression of KLKB1 mRNA CTD PMID:16595896 NCBI chr16:46,958,634...46,982,054 JBrowse link
G Krt7 keratin 7 increases expression ISO kojic acid results in increased expression of KRT7 mRNA CTD PMID:16595896 NCBI chr 7:132,528,863...132,545,052 JBrowse link
G Ktn1 kinectin 1 decreases expression ISO kojic acid results in decreased expression of KTN1 mRNA CTD PMID:16595896 NCBI chr15:20,913,665...21,002,588 JBrowse link
G Larp7 La ribonucleoprotein 7, transcriptional regulator decreases expression ISO kojic acid results in decreased expression of LARP7 mRNA CTD PMID:16595896 NCBI chr 2:215,997,641...216,012,833 JBrowse link
G Lilrb3 leukocyte immunoglobulin like receptor B3 decreases expression ISO kojic acid results in decreased expression of LILRB5 mRNA CTD PMID:16595896 NCBI chr 1:69,928,948...69,939,461 JBrowse link
G LOC102555183 zinc finger protein OZF-like decreases expression ISO kojic acid results in decreased expression of ZNF146 mRNA CTD PMID:16595896 NCBI chr 1:85,409,570...85,421,884 JBrowse link
G LOC103690190 histone H2A type 1-E increases expression ISO kojic acid results in increased expression of H2AC6 mRNA CTD PMID:16595896 NCBI chr17:42,707,863...42,708,420 JBrowse link
G Lrp6 LDL receptor related protein 6 decreases expression ISO kojic acid results in decreased expression of LRP6 mRNA CTD PMID:16595896 NCBI chr 4:167,266,581...167,400,155 JBrowse link
G Lrrc4 leucine rich repeat containing 4 decreases expression ISO kojic acid results in decreased expression of LRRC4 mRNA CTD PMID:16595896 NCBI chr 4:57,433,518...57,437,114 JBrowse link
G Lrrc9 leucine rich repeat containing 9 increases expression ISO kojic acid results in increased expression of LRRC9 mRNA CTD PMID:16595896 NCBI chr 6:91,017,739...91,095,847 JBrowse link
G Maea macrophage erythroblast attacher, E3 ubiquitin ligase increases expression ISO kojic acid results in increased expression of MAEA mRNA CTD PMID:16595896 NCBI chr14:77,357,261...77,390,683 JBrowse link
G Mafk MAF bZIP transcription factor K decreases expression ISO kojic acid results in decreased expression of MAFK mRNA CTD PMID:16595896 NCBI chr12:14,834,628...14,856,414 JBrowse link
G Magec2 MAGE family member C2 increases expression ISO kojic acid results in increased expression of MAGEC2 mRNA CTD PMID:16595896 NCBI chr  X:140,610,610...140,615,484 JBrowse link
G Maoa monoamine oxidase A multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MAOA mRNA CTD PMID:18544905 NCBI chr  X:6,032,172...6,098,308 JBrowse link
G Maob monoamine oxidase B multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MAOB mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of MAOB mRNA CTD PMID:18544905 NCBI chr  X:5,907,327...6,010,996 JBrowse link
G Map7d2 MAP7 domain containing 2 decreases expression ISO kojic acid results in decreased expression of MAP7D2 mRNA CTD PMID:16595896 NCBI chr  X:35,372,453...35,488,073 JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO kojic acid results in decreased phosphorylation of MAPK1 protein CTD PMID:27586645 NCBI chr11:83,957,813...84,023,629 JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO kojic acid results in decreased phosphorylation of MAPK3 protein CTD PMID:27586645 NCBI chr 1:181,366,646...181,372,863 JBrowse link
G Mapk8 mitogen-activated protein kinase 8 decreases expression ISO kojic acid results in decreased expression of MAPK8 mRNA CTD PMID:16595896 NCBI chr16:8,638,897...8,721,960 JBrowse link
G Mbnl1 muscleblind-like splicing regulator 1 decreases expression ISO kojic acid results in decreased expression of MBNL1 mRNA CTD PMID:16595896 NCBI chr 2:144,639,819...144,814,395 JBrowse link
G Mc1r melanocortin 1 receptor decreases expression ISO kojic acid results in decreased expression of MC1R protein CTD PMID:27586645 NCBI chr19:51,452,448...51,455,375 JBrowse link
G Mdfi MyoD family inhibitor decreases expression ISO kojic acid results in decreased expression of MDFI mRNA CTD PMID:16595896 NCBI chr 9:13,156,806...13,175,218 JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MDM2 mRNA CTD PMID:18544905 NCBI chr 7:53,290,660...53,315,205 JBrowse link
G Me3 malic enzyme 3 decreases expression ISO kojic acid results in decreased expression of ME3 mRNA CTD PMID:16595896 NCBI chr 1:143,534,024...143,735,551 JBrowse link
G Med14 mediator complex subunit 14 increases expression ISO kojic acid results in increased expression of MED14 mRNA CTD PMID:16595896 NCBI chr  X:10,036,749...10,127,910 JBrowse link
G Mex3b mex-3 RNA binding family member B increases expression ISO kojic acid results in increased expression of MEX3B mRNA CTD PMID:16595896 NCBI chr 1:136,855,130...136,859,365 JBrowse link
G Mfap4 microfibril associated protein 4 decreases expression ISO kojic acid results in decreased expression of MFAP4 mRNA CTD PMID:16595896 NCBI chr10:46,167,158...46,170,176 JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase multiple interactions EXP [kojic acid co-treated with Diethylnitrosamine] results in increased expression of MGMT mRNA; Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of MGMT mRNA] CTD PMID:18544905 NCBI chr 1:191,710,980...191,937,760 JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MGST1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of MGST1 mRNA CTD PMID:18544905 NCBI chr 4:171,029,666...171,044,893 JBrowse link
G Midn midnolin decreases expression ISO kojic acid results in decreased expression of MIDN mRNA CTD PMID:16595896 NCBI chr 7:9,548,100...9,559,605 JBrowse link
G Mif macrophage migration inhibitory factor multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MIF mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of MIF mRNA CTD PMID:18544905 NCBI chr20:12,790,919...12,791,784 JBrowse link
G Mnd1 meiotic nuclear divisions 1 increases expression ISO kojic acid results in increased expression of GAJ mRNA CTD PMID:16595896 NCBI chr 2:169,433,538...169,496,081 JBrowse link
G Mrpl30 mitochondrial ribosomal protein L30 decreases expression ISO kojic acid results in decreased expression of MRPL30 mRNA CTD PMID:16595896 NCBI chr 9:40,125,352...40,136,189 JBrowse link
G Mtrex Mtr4 exosome RNA helicase decreases expression ISO kojic acid results in decreased expression of MTREX mRNA CTD PMID:16595896 NCBI chr 2:44,500,326...44,560,624 JBrowse link
G Mvp major vault protein multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MVP mRNA CTD PMID:18544905 NCBI chr 1:181,594,734...181,622,336 JBrowse link
G Naa25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit increases expression ISO kojic acid results in increased expression of NAA25 mRNA CTD PMID:16595896 NCBI chr12:35,098,075...35,150,544 JBrowse link
G Ncald neurocalcin delta decreases expression ISO kojic acid results in decreased expression of NCALD mRNA CTD PMID:16595896 NCBI chr 7:68,532,671...68,964,740 JBrowse link
G Ndufa1 NADH:ubiquinone oxidoreductase subunit A1 increases expression ISO kojic acid results in increased expression of NDUFA1 mRNA CTD PMID:16595896 NCBI chr  X:116,424,223...116,427,875 JBrowse link
G Nectin4 nectin cell adhesion molecule 4 increases expression ISO kojic acid results in increased expression of NECTIN4 mRNA CTD PMID:16595896 NCBI chr13:83,802,589...83,821,711 JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated increases expression ISO kojic acid results in increased expression of NFIL3 mRNA CTD PMID:16595896 NCBI chr17:12,280,499...12,295,728 JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of NFKBIA mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of NFKBIA mRNA CTD PMID:18544905 NCBI chr 6:72,858,713...72,861,941 JBrowse link
G Nfkbie NFKB inhibitor epsilon increases expression ISO kojic acid results in increased expression of NFKBIE mRNA CTD PMID:16595896 NCBI chr 9:15,443,600...15,450,437 JBrowse link
G Nkx6-1 NK6 homeobox 1 decreases expression ISO kojic acid results in decreased expression of NKX6-1 mRNA CTD PMID:16595896 NCBI chr14:7,969,756...7,976,689 JBrowse link
G Nlgn2 neuroligin 2 decreases expression ISO kojic acid results in decreased expression of NLGN2 mRNA CTD PMID:16595896 NCBI chr10:54,544,588...54,557,854 JBrowse link
G Noc3l NOC3-like DNA replication regulator decreases expression ISO kojic acid results in decreased expression of NOC3L mRNA CTD PMID:16595896 NCBI chr 1:236,556,037...236,585,372 JBrowse link
G Nol11 nucleolar protein 11 decreases expression ISO kojic acid results in decreased expression of NOL11 mRNA CTD PMID:16595896 NCBI chr10:92,119,000...92,141,688 JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of NR1I2 mRNA CTD PMID:18544905 NCBI chr11:62,460,213...62,496,665 JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of NR1I3 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of NR1I3 mRNA CTD PMID:18544905 NCBI chr13:83,632,940...83,638,193 JBrowse link
G Odad2 outer dynein arm docking complex subunit 2 increases expression ISO kojic acid results in increased expression of ODAD2 mRNA CTD PMID:16595896 NCBI chr17:55,216,877...55,409,872 JBrowse link
G Olfml1 olfactomedin-like 1 decreases expression ISO kojic acid results in decreased expression of OLFML1 mRNA CTD PMID:16595896 NCBI chr 1:161,478,129...161,502,541 JBrowse link
G Olr130 olfactory receptor 130 decreases expression ISO kojic acid results in decreased expression of OR51B4 mRNA CTD PMID:16595896 NCBI chr 1:158,317,228...158,318,151 JBrowse link
G Osbp2 oxysterol binding protein 2 decreases expression ISO kojic acid results in decreased expression of OSBP2 mRNA CTD PMID:16595896 NCBI chr14:78,585,088...78,746,785 JBrowse link
G Ostm1 osteoclastogenesis associated transmembrane protein 1 decreases expression ISO kojic acid results in decreased expression of OSTM1 mRNA CTD PMID:16595896 NCBI chr20:46,071,657...46,187,049 JBrowse link
G Otx1 orthodenticle homeobox 1 increases expression ISO kojic acid results in increased expression of OTX1 mRNA CTD PMID:16595896 NCBI chr14:96,082,151...96,089,161 JBrowse link
G Pabir1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 increases expression ISO kojic acid results in increased expression of PABIR1 mRNA CTD PMID:16595896 NCBI chr 1:222,114,988...222,116,294 JBrowse link
G Pagr1 Paxip1-associated glutamate-rich protein 1 increases expression ISO kojic acid results in increased expression of PAGR1 mRNA CTD PMID:16595896 NCBI chr 1:181,622,708...181,624,996 JBrowse link
G Pah phenylalanine hydroxylase decreases expression ISO kojic acid results in decreased expression of PAH mRNA CTD PMID:16595896 NCBI chr 7:21,933,179...21,998,134 JBrowse link
G Parg poly (ADP-ribose) glycohydrolase increases expression ISO kojic acid results in increased expression of PARG mRNA CTD PMID:16595896 NCBI chr16:7,436,429...7,544,276 JBrowse link
G Pbk PDZ binding kinase decreases expression ISO kojic acid results in decreased expression of PBK mRNA CTD PMID:16595896 NCBI chr15:40,022,873...40,034,014 JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO
EXP
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of PCNA protein
[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of PCNA protein
CTD PMID:17917374 PMID:18544905 NCBI chr 3:119,499,039...119,502,911 JBrowse link
G Pcnx3 pecanex 3 decreases expression ISO kojic acid results in decreased expression of PCNX3 mRNA CTD PMID:16595896 NCBI chr 1:202,951,322...202,974,167 JBrowse link
G Pcsk4 proprotein convertase subtilisin/kexin type 4 decreases expression ISO kojic acid results in decreased expression of PCSK4 mRNA CTD PMID:16595896 NCBI chr 7:9,381,366...9,389,589 JBrowse link
G Pdcl phosducin-like increases expression ISO kojic acid results in increased expression of PDCL mRNA CTD PMID:16595896 NCBI chr 3:21,110,165...21,119,763 JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 increases expression ISO kojic acid results in increased expression of PDHA1 mRNA CTD PMID:16595896 NCBI chr  X:34,700,481...34,714,309 JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of PDIA3 mRNA CTD PMID:18544905 NCBI chr 3:108,388,189...108,412,013 JBrowse link
G Pdlim2 PDZ and LIM domain 2 increases expression ISO kojic acid results in increased expression of PDLIM2 mRNA CTD PMID:16595896 NCBI chr15:45,235,421...45,250,187 JBrowse link
G Perm1 PPARGC1 and ESRR induced regulator, muscle 1 decreases expression ISO kojic acid results in decreased expression of PERM1 mRNA CTD PMID:16595896 NCBI chr 5:166,800,030...166,805,323 JBrowse link
G Pex5l peroxisomal biogenesis factor 5-like decreases expression ISO kojic acid results in decreased expression of PEX5L mRNA CTD PMID:16595896 NCBI chr 2:115,694,868...115,908,338 JBrowse link
G Pgm2 phosphoglucomutase 2 increases expression ISO kojic acid results in increased expression of PGM2 mRNA CTD PMID:16595896 NCBI chr14:44,166,314...44,199,823 JBrowse link
G Pigq phosphatidylinositol glycan anchor biosynthesis, class Q decreases expression ISO kojic acid results in decreased expression of PIGQ mRNA CTD PMID:16595896 NCBI chr10:14,942,571...14,958,584 JBrowse link
G Pitpnb phosphatidylinositol transfer protein, beta increases expression ISO kojic acid results in increased expression of PITPNB mRNA CTD PMID:16595896 NCBI chr12:45,249,308...45,298,388 JBrowse link
G Plagl1 PLAG1 like zinc finger 1 increases expression ISO kojic acid results in increased expression of PLAGL1 mRNA CTD PMID:16595896 NCBI chr 1:7,477,295...7,517,229 JBrowse link
G Poglut2 protein O-glucosyltransferase 2 increases expression ISO kojic acid results in increased expression of POGLUT2 mRNA CTD PMID:16595896 NCBI chr 9:46,256,388...46,268,714 JBrowse link
G Pon3 paraoxonase 3 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of PON3 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of PON3 mRNA CTD PMID:18544905 NCBI chr 4:33,356,983...33,383,681 JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of POR mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of POR mRNA CTD PMID:18544905 NCBI chr12:20,951,058...20,999,198 JBrowse link
G Pou2f3 POU class 2 homeobox 3 decreases expression ISO kojic acid results in decreased expression of POU2F3 mRNA CTD PMID:16595896 NCBI chr 8:43,495,408...43,577,795 JBrowse link
G Ppp4r1 protein phosphatase 4, regulatory subunit 1 increases expression ISO kojic acid results in increased expression of PPP4R1 mRNA CTD PMID:16595896 NCBI chr 9:105,391,271...105,450,626 JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions EXP [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of PRDX1 mRNA CTD PMID:18544905 NCBI chr 5:130,147,276...130,162,850 JBrowse link
G Prdx2 peroxiredoxin 2 multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of PRDX2 mRNA CTD PMID:18544905 NCBI chr19:23,180,927...23,186,217 JBrowse link
G Prg2 proteoglycan 2 decreases expression ISO kojic acid results in decreased expression of PRG2 mRNA CTD PMID:16595896 NCBI chr 3:70,062,535...70,066,102 JBrowse link
G Prickle3 prickle planar cell polarity protein 3 decreases expression ISO kojic acid results in decreased expression of PRICKLE3 mRNA CTD PMID:16595896 NCBI chr  X:14,837,647...14,849,305 JBrowse link
G Prim1 DNA primase subunit 1 decreases expression ISO kojic acid results in decreased expression of PRIM1 mRNA CTD PMID:16595896 NCBI chr 7:446,342...462,526 JBrowse link
G Prmt2 protein arginine methyltransferase 2 decreases expression ISO kojic acid results in decreased expression of PRMT2 mRNA CTD PMID:16595896 NCBI chr20:12,394,748...12,420,643 JBrowse link
G Prpf40a pre-mRNA processing factor 40 homolog A decreases expression ISO kojic acid results in decreased expression of PRPF40A mRNA CTD PMID:16595896 NCBI chr 3:37,625,585...37,689,859 JBrowse link
G Prps2 phosphoribosyl pyrophosphate synthetase 2 increases expression ISO kojic acid results in increased expression of PRPS2 mRNA CTD PMID:16595896 NCBI chr  X:26,975,915...27,013,184 JBrowse link
G Prr18 proline rich 18 decreases expression ISO kojic acid results in decreased expression of PRR18 mRNA CTD PMID:16595896 NCBI chr 1:52,400,215...52,404,492 JBrowse link
G Prrc2c proline-rich coiled-coil 2C increases expression ISO kojic acid results in increased expression of PRRC2C mRNA CTD PMID:16595896 NCBI chr13:75,003,995...75,073,701 JBrowse link
G Prrx1 paired related homeobox 1 decreases expression ISO kojic acid results in decreased expression of PRRX1 mRNA CTD PMID:16595896 NCBI chr13:75,600,777...75,671,896 JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 decreases expression ISO kojic acid results in decreased expression of PSMC6 mRNA CTD PMID:16595896 NCBI chr15:18,542,585...18,564,057 JBrowse link
G Psmd3 proteasome 26S subunit, non-ATPase 3 decreases expression ISO kojic acid results in decreased expression of PSMD3 mRNA CTD PMID:16595896 NCBI chr10:83,643,473...83,655,620 JBrowse link
G Pus7l pseudouridine synthase 7 like decreases expression ISO kojic acid results in decreased expression of PUS7L mRNA CTD PMID:16595896 NCBI chr 7:125,659,507...125,706,582 JBrowse link
G Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1 increases expression ISO kojic acid results in increased expression of RAB3GAP1 mRNA CTD PMID:16595896 NCBI chr13:39,355,698...39,429,154 JBrowse link
G Rab6b RAB6B, member RAS oncogene family decreases expression ISO kojic acid results in decreased expression of RAB6B mRNA CTD PMID:16595896 NCBI chr 8:103,695,328...103,764,023 JBrowse link
G Rad1 RAD1 checkpoint DNA exonuclease increases expression ISO kojic acid results in increased expression of RAD1 mRNA CTD PMID:16595896 NCBI chr 2:59,461,597...59,469,707 JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of RAD23A mRNA CTD PMID:18544905 NCBI chr19:23,313,563...23,320,702 JBrowse link
G Rad50 RAD50 double strand break repair protein multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of RAD50 mRNA CTD PMID:17917374 NCBI chr10:37,809,353...37,861,309 JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of RARA mRNA CTD PMID:18544905 NCBI chr10:83,883,490...83,928,932 JBrowse link
G Rarb retinoic acid receptor, beta multiple interactions EXP [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of RARB mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of RARB mRNA CTD PMID:18544905 NCBI chr15:8,700,533...9,051,288 JBrowse link
G Rasd1 ras related dexamethasone induced 1 increases expression ISO kojic acid results in increased expression of RASD1 mRNA CTD PMID:16595896 NCBI chr10:44,766,451...44,775,773 JBrowse link
G Rasgef1b RasGEF domain family, member 1B decreases expression ISO kojic acid results in decreased expression of RASGEF1B mRNA CTD PMID:16595896 NCBI chr14:9,859,512...10,380,044 JBrowse link
G Rassf3 Ras association domain family member 3 increases expression ISO kojic acid results in increased expression of RASSF3 mRNA CTD PMID:16595896 NCBI chr 7:56,935,894...57,000,591 JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 decreases expression ISO kojic acid results in decreased expression of RB1CC1 mRNA CTD PMID:16595896 NCBI chr 5:13,161,648...13,225,560 JBrowse link
G Rbm38 RNA binding motif protein 38 decreases expression ISO kojic acid results in decreased expression of RBM38 mRNA CTD PMID:16595896 NCBI chr 3:161,801,550...161,814,381 JBrowse link
G Recql RecQ like helicase decreases expression ISO kojic acid results in decreased expression of RECQL mRNA CTD PMID:16595896 NCBI chr 4:175,308,337...175,332,965 JBrowse link
G RGD1311164 similar to DNA segment, Chr 6, Wayne State University 163, expressed decreases expression ISO kojic acid results in decreased expression of C12ORF4 mRNA CTD PMID:16595896 NCBI chr 4:159,772,693...159,809,322 JBrowse link
G RGD1560146 similar to hypothetical protein MGC34837 decreases expression ISO kojic acid results in decreased expression of C1ORF87 mRNA CTD PMID:16595896 NCBI chr 5:111,342,381...111,411,576 JBrowse link
G RGD1562218 similar to RIKEN cDNA 0610039J04 decreases expression ISO kojic acid results in decreased expression of C1ORF131 mRNA CTD PMID:16595896 NCBI chr19:52,807,932...52,822,259 JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 decreases expression ISO kojic acid results in decreased expression of RIMS2 mRNA CTD PMID:16595896 NCBI chr 7:70,248,104...70,759,134 JBrowse link
G Rsbn1 round spermatid basic protein 1 decreases expression ISO kojic acid results in decreased expression of RSBN1 mRNA CTD PMID:16595896 NCBI chr 2:191,416,631...191,470,711 JBrowse link
G Saa4 serum amyloid A4 decreases expression ISO kojic acid results in decreased expression of SAA4 mRNA CTD PMID:16595896 NCBI chr 1:97,247,580...97,251,882 JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression ISO kojic acid results in increased expression of SCARB1 mRNA CTD PMID:19000923 NCBI chr12:31,296,143...31,362,649 JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 decreases expression ISO kojic acid results in decreased expression of SCN10A mRNA CTD PMID:16595896 NCBI chr 8:119,350,723...119,462,882 JBrowse link
G Scp2 sterol carrier protein 2 decreases expression ISO kojic acid results in decreased expression of SCP2 mRNA CTD PMID:16595896 NCBI chr 5:122,806,949...122,881,259 JBrowse link
G Sdc4 syndecan 4 decreases expression ISO kojic acid results in decreased expression of SDC4 mRNA CTD PMID:16595896 NCBI chr 3:153,154,888...153,173,576 JBrowse link
G Sec24b SEC24 homolog B, COPII coat complex component increases expression ISO kojic acid results in increased expression of SEC24B mRNA CTD PMID:16595896 NCBI chr 2:218,562,670...218,632,753 JBrowse link
G Sec62 SEC62 homolog, preprotein translocation factor decreases expression ISO kojic acid results in decreased expression of SEC62 mRNA CTD PMID:16595896 NCBI chr 2:112,570,810...112,607,576 JBrowse link
G Sectm1b secreted and transmembrane 1B decreases expression ISO kojic acid results in decreased expression of SECTM1 mRNA CTD PMID:16595896 NCBI chr10:106,325,202...106,333,769 JBrowse link
G Septin7 septin 7 decreases expression ISO kojic acid results in decreased expression of SEPTIN7 mRNA CTD PMID:16595896 NCBI chr 8:23,719,448...23,783,247 JBrowse link
G Serpina5 serpin family A member 5 decreases expression ISO kojic acid results in decreased expression of SERPINA5 mRNA CTD PMID:16595896 NCBI chr 6:123,009,224...123,028,412 JBrowse link
G Shcbp1 SHC binding and spindle associated 1 increases expression ISO kojic acid results in increased expression of SHCBP1 mRNA CTD PMID:16595896 NCBI chr16:84,672,276...84,703,839 JBrowse link
G Sin3b SIN3 transcription regulator family member B decreases expression ISO kojic acid results in decreased expression of SIN3B mRNA CTD PMID:16595896 NCBI chr16:17,123,277...17,160,070 JBrowse link
G Slc17a2 solute carrier family 17, member 2 decreases expression ISO kojic acid results in decreased expression of SLC17A2 mRNA CTD PMID:16595896 NCBI chr17:41,318,312...41,339,012 JBrowse link
G Slc25a2 solute carrier family 25 member 2 decreases expression ISO kojic acid results in decreased expression of SLC25A2 mRNA CTD PMID:16595896 NCBI chr18:29,452,943...29,457,906 JBrowse link