Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N,N-dimethyl-4-nitrosoaniline
go back to main search page
Accession:CHEBI:59990 term browser browse the term
Definition:A member of the class of dimethylanilines that is N,N-dimethylaniline having a nitroso group at the 4-position.
Synonyms:related_synonym: 4-(Dimethylamino)nitrosobenzene;   4-Nitroso-N,N-dimethylaniline;   4-Nitrosodimethylaniline;   Dimethyl(p-nitrosophenyl)amine;   Dimethyl-p-nitrosoaniline;   Formula=C8H10N2O;   InChI=1S/C8H10N2O/c1-10(2)8-5-3-7(9-11)4-6-8/h3-6H,1-2H3;   InChIKey=CMEWLCATCRTSGF-UHFFFAOYSA-N;   N,N-Dimethyl-p-nitrosoaniline;   NDMA;   Paranitrosodimethylanilide;   SMILES=CN(C)c1ccc(cc1)N=O;   p-(Dimethylamino)nitrosobenzene;   p-(N,N-Dimethylamino)nitrosobenzene;   p-Nitroso dimethylaniline;   p-Nitroso-N,N-dimethylaniline;   p-Nitrosodimethylanilide
 xref: AGR:IND23280673;   CAS:138-89-6;   Gmelin:27528;   KEGG:C19680
 xref_mesh: MESH:C008651
 xref: MetaCyc:CPD-12424;   PMID:19785421;   PMID:4335090;   PMID:5234495;   PMID:8930732;   PMID:972772;   Reaxys:607293


show annotations for term's descendants           Sort by:
 
N,N-dimethyl-4-nitrosoaniline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mgmt O-6-methylguanine-DNA methyltransferase decreases expression ISO
EXP
4-nitrosodimethylaniline results in decreased expression of MGMT protein CTD PMID:15542103 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19786
    chemical entity 19786
      group 19705
        inorganic group 19196
          nitroso group 5011
            nitroso compound 5011
              N,N-dimethyl-4-nitrosoaniline 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19786
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19675
                    main group molecular entity 19675
                      s-block molecular entity 19443
                        hydrogen molecular entity 19439
                          hydrides 18763
                            inorganic hydride 17484
                              pnictogen hydride 17461
                                nitrogen hydride 17315
                                  azane 17021
                                    ammonia 17020
                                      organic amino compound 17019
                                        aromatic amine 13685
                                          anilines 12362
                                            substituted aniline 11854
                                              methylaniline 8
                                                dimethylaniline 8
                                                  N,N-dimethyl-4-nitrosoaniline 1
paths to the root