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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N,N-dimethyl-4-nitrosoaniline
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Accession:CHEBI:59990 term browser browse the term
Definition:A member of the class of dimethylanilines that is N,N-dimethylaniline having a nitroso group at the 4-position.
Synonyms:related_synonym: 4-(Dimethylamino)nitrosobenzene;   4-Nitroso-N,N-dimethylaniline;   4-Nitrosodimethylaniline;   Dimethyl(p-nitrosophenyl)amine;   Dimethyl-p-nitrosoaniline;   Formula=C8H10N2O;   InChI=1S/C8H10N2O/c1-10(2)8-5-3-7(9-11)4-6-8/h3-6H,1-2H3;   InChIKey=CMEWLCATCRTSGF-UHFFFAOYSA-N;   N,N-Dimethyl-p-nitrosoaniline;   NDMA;   Paranitrosodimethylanilide;   SMILES=CN(C)c1ccc(cc1)N=O;   p-(Dimethylamino)nitrosobenzene;   p-(N,N-Dimethylamino)nitrosobenzene;   p-Nitroso dimethylaniline;   p-Nitroso-N,N-dimethylaniline;   p-Nitrosodimethylanilide
 xref: AGR:IND23280673;   CAS:138-89-6;   Gmelin:27528;   KEGG:C19680
 xref_mesh: MESH:C008651
 xref: MetaCyc:CPD-12424;   PMID:19785421;   PMID:4335090;   PMID:5234495;   PMID:8930732;   PMID:972772;   Reaxys:607293



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N,N-dimethyl-4-nitrosoaniline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mgmt O-6-methylguanine-DNA methyltransferase decreases expression ISO
EXP
4-nitrosodimethylaniline results in decreased expression of MGMT protein CTD PMID:15542103 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    chemical entity 19739
      group 19701
        inorganic group 19316
          nitroso group 5029
            nitroso compound 5029
              N,N-dimethyl-4-nitrosoaniline 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19739
      composite particle 19739
        hadron 19739
          baryon 19739
            nucleon 19739
              atomic nucleus 19739
                atom 19739
                  main group element atom 19687
                    main group molecular entity 19687
                      s-block molecular entity 19539
                        hydrogen molecular entity 19532
                          hydrides 19014
                            inorganic hydride 17945
                              pnictogen hydride 17930
                                nitrogen hydride 17825
                                  azane 17606
                                    ammonia 17605
                                      organic amino compound 17605
                                        aromatic amine 14995
                                          anilines 13965
                                            substituted aniline 13640
                                              methylaniline 10
                                                dimethylaniline 10
                                                  N,N-dimethyl-4-nitrosoaniline 1
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