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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N,N-dimethyl-4-nitrosoaniline
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Accession:CHEBI:59990 term browser browse the term
Definition:A member of the class of dimethylanilines that is N,N-dimethylaniline having a nitroso group at the 4-position.
Synonyms:related_synonym: 4-(Dimethylamino)nitrosobenzene;   4-Nitroso-N,N-dimethylaniline;   4-Nitrosodimethylaniline;   Dimethyl(p-nitrosophenyl)amine;   Dimethyl-p-nitrosoaniline;   Formula=C8H10N2O;   InChI=1S/C8H10N2O/c1-10(2)8-5-3-7(9-11)4-6-8/h3-6H,1-2H3;   InChIKey=CMEWLCATCRTSGF-UHFFFAOYSA-N;   N,N-Dimethyl-p-nitrosoaniline;   NDMA;   Paranitrosodimethylanilide;   SMILES=CN(C)c1ccc(cc1)N=O;   p-(Dimethylamino)nitrosobenzene;   p-(N,N-Dimethylamino)nitrosobenzene;   p-Nitroso dimethylaniline;   p-Nitroso-N,N-dimethylaniline;   p-Nitrosodimethylanilide
 xref: AGR:IND23280673;   CAS:138-89-6;   Gmelin:27528;   KEGG:C19680
 xref_mesh: MESH:C008651
 xref: MetaCyc:CPD-12424;   PMID:19785421;   PMID:4335090;   PMID:5234495;   PMID:8930732;   PMID:972772;   Reaxys:607293



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N,N-dimethyl-4-nitrosoaniline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mgmt O-6-methylguanine-DNA methyltransferase decreases expression ISO
EXP
4-nitrosodimethylaniline results in decreased expression of MGMT protein CTD PMID:15542103 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19863
    chemical entity 19861
      group 19819
        inorganic group 19401
          nitroso group 5069
            nitroso compound 5069
              N,N-dimethyl-4-nitrosoaniline 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19863
    subatomic particle 19861
      composite particle 19861
        hadron 19861
          baryon 19861
            nucleon 19861
              atomic nucleus 19861
                atom 19861
                  main group element atom 19807
                    main group molecular entity 19807
                      s-block molecular entity 19639
                        hydrogen molecular entity 19620
                          hydrides 19126
                            inorganic hydride 18134
                              pnictogen hydride 18123
                                nitrogen hydride 18032
                                  azane 17837
                                    ammonia 17836
                                      organic amino compound 17836
                                        aromatic amine 15492
                                          anilines 14427
                                            substituted aniline 14068
                                              methylaniline 10
                                                dimethylaniline 10
                                                  N,N-dimethyl-4-nitrosoaniline 1
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