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ONTOLOGY REPORT - ANNOTATIONS


Term:HIV fusion inhibitor
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Accession:CHEBI:59886 term browser browse the term
Definition:A drug which interferes with the binding, fusion and entry of an HIV virion to a human cell. By blocking this step in HIV's replication cycle, such agents slow the progression from HIV infection to AIDS.
Synonyms:related_synonym: HIV entry inhibitor;   HIV entry inhibitors;   HIV fusion inhibitors
 xref: PMID:22470838 "Europe PMC";   Wikipedia:Entry_inhibitor


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enfuvirtide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464
maraviroc term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actn2 actinin alpha 2 JBrowse link 17 66,304,530 66,397,647 RGD:6480464
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:6480464
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:6480464
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:6480464
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:6480464
G Col1a2 collagen type I alpha 2 chain JBrowse link 4 31,534,225 31,569,152 RGD:6480464
G Myh6 myosin heavy chain 6 JBrowse link 15 33,605,653 33,629,730 RGD:6480464
G Ryr2 ryanodine receptor 2 JBrowse link 17 65,533,998 65,955,606 RGD:6480464
G Tnnt2 troponin T2, cardiac type JBrowse link 13 52,662,974 52,680,992 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        antimicrobial agent 17211
          antiviral agent 3709
            antiviral drug 1776
              HIV fusion inhibitor 12
                enfuvirtide 3
                maraviroc 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      application 19328
        pharmaceutical 19202
          drug 19202
            antiinfective agent 12926
              antimicrobial drug 6129
                antiviral drug 1776
                  HIV fusion inhibitor 12
                    enfuvirtide 3
                    maraviroc 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.