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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:monothioacetal
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Accession:CHEBI:59793 term browser browse the term
Definition:A thioacetal having the structure R2C(OR')(SR'). The term includes monothioketals, R =/= H, as a subclass.
Synonyms:related_synonym: Formula=COSR4;   SMILES=[*]OC([*])([*])S[*];   monothioacetals;   thioacetal



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auranofin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin affects binding ISO Auranofin analog binds to ALB protein CTD PMID:16791640 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases response to substance
ISO [BAX co-treated with BAK1] results in increased susceptibility to Auranofin; BAK1 mutant form inhibits the reaction [Auranofin results in increased activity of CASP3 protein]
BAK1 results in increased susceptibility to Auranofin
CTD PMID:18789312 PMID:21172426 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases response to substance
ISO [BAX co-treated with BAK1] results in increased susceptibility to Auranofin; BAX mutant form inhibits the reaction [Auranofin results in increased activity of CASP3 protein]
BAX results in increased susceptibility to Auranofin
CTD PMID:18789312 PMID:21172426 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO BCL2 protein inhibits the reaction [Auranofin results in increased activity of CASP3 protein] CTD PMID:18789312 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO
EXP
Auranofin promotes the reaction [TNF protein results in increased activity of CASP3 protein]; Auranofin results in decreased expression of and results in increased cleavage of CASP3 protein; BCL2 protein inhibits the reaction [Auranofin results in increased activity of CASP3 protein]
BAK1 mutant form inhibits the reaction [Auranofin results in increased activity of CASP3 protein]; BAX mutant form inhibits the reaction [Auranofin results in increased activity of CASP3 protein]
CTD PMID:15159275 PMID:15191400 PMID:18789312 PMID:20542334 PMID:21699084 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO Auranofin results in decreased expression of and results in increased cleavage of CASP8 protein CTD PMID:20542334 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Auranofin results in decreased expression of and results in increased cleavage of CASP9 protein CTD PMID:20542334 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Auranofin results in increased expression of CDKN1A protein CTD PMID:20542334 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cebpe CCAAT/enhancer binding protein epsilon multiple interactions ISO [Auranofin co-treated with Tretinoin] results in increased expression of CEBPE protein CTD PMID:15159275 NCBI chr15:28,169,885...28,171,283
Ensembl chr15:28,169,704...28,171,814
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO Auranofin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CHUK protein]; Auranofin inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein]
Auranofin inhibits the reaction [TNF protein results in increased activity of CHUK protein]
CTD PMID:10820281 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression
ISO [Peptidoglycan co-treated with Lipopolysaccharides] promotes the reaction [Auranofin results in increased expression of GPX1 protein]; Auranofin promotes the reaction [[Lipopolysaccharides co-treated with Peptidoglycan] results in increased expression of GPX1 protein] CTD PMID:21355852 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Auranofin results in increased expression of HMOX1 mRNA
Auranofin results in increased expression of HMOX1 mRNA; Auranofin results in increased expression of HMOX1 protein
CTD PMID:22008538 PMID:23942037 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Auranofin inhibits the reaction [IL1B protein affects the localization of RELA protein]; Auranofin inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Auranofin inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] CTD PMID:10594346 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Auranofin co-treated with IL6 protein] results in decreased phosphorylation of IL6ST protein; [Auranofin co-treated with IL6 protein] results in decreased phosphorylation of JAK2 protein; [Auranofin co-treated with IL6 protein] results in decreased phosphorylation of STAT3 protein CTD PMID:20542334 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6st interleukin 6 cytokine family signal transducer multiple interactions ISO [Auranofin co-treated with IL6 protein] results in decreased phosphorylation of IL6ST protein CTD PMID:20542334 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 multiple interactions ISO Auranofin inhibits the reaction [lipopolysaccharide A results in increased degradation of IRAK1 protein] CTD PMID:17034761 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521
JBrowse link
G Irf3 interferon regulatory factor 3 multiple interactions ISO Auranofin inhibits the reaction [lipopolysaccharide A results in increased activity of IRF3 protein]; Auranofin inhibits the reaction [lipopolysaccharide A results in increased phosphorylation of IRF3 protein]; Auranofin inhibits the reaction [TBK1 protein results in increased activity of IRF3 protein]; Auranofin inhibits the reaction [TICAM1 protein results in increased activity of IRF3 protein] CTD PMID:17034761 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO [Auranofin co-treated with Tretinoin] results in increased expression of ITGAM protein CTD PMID:15159275 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO [Auranofin co-treated with IL6 protein] results in decreased phosphorylation of JAK2 protein CTD PMID:20542334 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions
decreases expression
ISO [Auranofin co-treated with SN50 peptide] results in decreased expression of MCL1 protein
Auranofin results in decreased expression of MCL1 protein
CTD PMID:20542334 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Auranofin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:10820281 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions ISO Auranofin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIB protein] CTD PMID:10820281 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases activity
increases cleavage
ISO Auranofin results in decreased activity of PARP1 protein
Auranofin results in increased cleavage of PARP1 protein
CTD PMID:15159275 PMID:21370912 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Ppif peptidylprolyl isomerase F increases oxidation
multiple interactions
ISO
EXP
Auranofin results in increased oxidation of PPIF protein
Auranofin inhibits the reaction [[NADP co-treated with TXNRD1 protein] results in increased activity of PPIF protein]; Cyclosporine promotes the reaction [Auranofin results in increased oxidation of PPIF protein]
CTD PMID:26975474 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913
JBrowse link
G Prdx3 peroxiredoxin 3 increases oxidation
multiple interactions
ISO
EXP
Auranofin results in increased oxidation of PRDX3 protein
Cyclosporine promotes the reaction [Auranofin results in increased oxidation of PRDX3 protein]
Auranofin promotes the reaction [[Lipopolysaccharides co-treated with Peptidoglycan] results in increased expression of PRDX3 protein]
CTD PMID:18789312 PMID:21355852 PMID:26975474 NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [lipopolysaccharide A co-treated with Auranofin] results in decreased expression of PTGS2 protein
Auranofin inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Auranofin inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]
CTD PMID:10594346 PMID:17034761 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO Auranofin results in decreased phosphorylation of RB1 protein CTD PMID:20542334 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Auranofin inhibits the reaction [IL1B protein affects the localization of RELA protein] CTD PMID:10594346 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G RT1-Ba RT1 class II, locus Ba increases response to substance ISO HLA-DQA1 gene polymorphism results in increased susceptibility to Auranofin CTD PMID:11436868 NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 increases response to substance ISO HLA-DRB1 gene polymorphism results in increased susceptibility to Auranofin CTD PMID:11436868 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Auranofin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases expression
multiple interactions
ISO Auranofin results in decreased expression of STAT3 protein modified form
[Auranofin co-treated with IL6 protein] results in decreased phosphorylation of STAT3 protein
CTD PMID:20542334 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tbk1 TANK-binding kinase 1 multiple interactions ISO Auranofin inhibits the reaction [TBK1 protein results in increased activity of IRF3 protein] CTD PMID:17034761 NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892
JBrowse link
G Ticam1 toll-like receptor adaptor molecule 1 multiple interactions ISO Auranofin inhibits the reaction [TICAM1 protein results in increased activity of IRF3 protein] CTD PMID:17034761 NCBI chr 9:1,102,559...1,115,573 JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO Auranofin inhibits the reaction [lipopolysaccharide A promotes the reaction [TLR4 protein binds to TLR4 protein]] CTD PMID:17034761 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Auranofin inhibits the reaction [TNF protein results in increased activity of CHUK protein]; Auranofin promotes the reaction [TNF protein results in increased activity of CASP3 protein]
Auranofin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
CTD PMID:10820281 PMID:18789312 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Txn1 thioredoxin 1 increases oxidation ISO Auranofin results in increased oxidation of TXN protein CTD PMID:26975474 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Txn2 thioredoxin 2 increases oxidation
multiple interactions
ISO
EXP
Auranofin results in increased oxidation of TXN2 protein
Cyclosporine promotes the reaction [Auranofin results in increased oxidation of TXN2 protein]
CTD PMID:26975474 NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions
decreases activity
increases oxidation
increases expression
ISO
EXP
Auranofin inhibits the reaction [Sodium Selenite results in increased activity of TXNRD1 protein]; Auranofin promotes the reaction [Sodium Selenite results in increased expression of TXNRD1 mRNA]; potassium tellurate(IV) promotes the reaction [Auranofin results in increased oxidation of TXNRD1 protein]; Sodium Selenite promotes the reaction [Auranofin results in increased oxidation of TXNRD1 protein]
Auranofin inhibits the reaction [[NADP co-treated with TXNRD1 protein] results in increased activity of PPIF protein]; Auranofin inhibits the reaction [[TXNRD1 protein co-treated with NADP] results in increased abundance of Superoxides]
Auranofin results in decreased activity of TXNRD1 protein
Auranofin results in increased expression of TXNRD1 mRNA
CTD PMID:16510263 PMID:18405881 PMID:18789312 PMID:19486940 PMID:20457604 More... NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Txnrd2 thioredoxin reductase 2 multiple interactions
decreases activity
ISO
EXP
Auranofin inhibits the reaction [Sodium Selenite results in increased activity of TXNRD2 protein]; Auranofin promotes the reaction [Sodium Selenite results in decreased expression of TXNRD2 mRNA]
Auranofin results in decreased activity of TXNRD2 protein
CTD PMID:15458826 PMID:19486940 PMID:21172426 PMID:21355852 NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
JBrowse link
clindamycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression
ISO Clindamycin results in increased expression of and results in increased activity of CYP3A4 protein
Clindamycin results in increased expression of CYP3A4 mRNA
CTD PMID:18505790 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression ISO Clindamycin results in increased expression of MMP13 mRNA CTD PMID:20338993 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 affects expression ISO Clindamycin affects the expression of HLA-DRB1 mRNA CTD PMID:25811541 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 affects expression ISO Clindamycin affects the expression of HLA-E mRNA CTD PMID:25811541 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
clindamycin phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pon1 paraoxonase 1 decreases activity ISO clindamycin phosphate results in decreased activity of PON1 protein CTD PMID:16880604 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
emtricitabine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin affects binding ISO Emtricitabine binds to ALB protein CTD PMID:15814459 PMID:16336266 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Emtricitabine co-treated with Tenofovir] results in increased expression of CDKN1A protein CTD PMID:31545371 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Dck deoxycytidine kinase multiple interactions
affects binding
ISO DCK protein results in increased phosphorylation of and results in increased activity of Emtricitabine
Emtricitabine binds to DCK protein
CTD PMID:17530837 NCBI chr14:19,305,218...19,326,247
Ensembl chr14:19,305,218...19,326,247
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase decreases expression
multiple interactions
ISO Emtricitabine results in decreased expression of PRKN protein
[Emtricitabine co-treated with Tenofovir] results in decreased expression of PRKN protein
CTD PMID:31545371 NCBI chr 1:48,688,651...49,882,520 JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Emtricitabine co-treated with Tenofovir] results in increased expression of TP53 protein CTD PMID:31545371 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
glucobrassicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpx2 glutathione peroxidase 2 multiple interactions
decreases expression
ISO glucobrassicin analog inhibits the reaction [glucoraphanin analog results in increased expression of GPX2 mRNA]
glucobrassicin analog results in decreased expression of GPX2 protein
CTD PMID:20868228 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
decreases activity
ISO glucobrassicin analog inhibits the reaction [glucoraphanin results in increased activity of NQO1 protein]
glucobrassicin analog results in decreased activity of NQO1 protein
CTD PMID:20868228 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
glucoerucin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP glucoerucin results in increased expression of CYP1A1 protein CTD PMID:20833222 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP glucoerucin results in increased expression of CYP1A2 protein CTD PMID:20833222 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression EXP glucoerucin results in increased expression of CYP1B1 protein CTD PMID:20833222 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP glucoerucin results in increased expression of EPHX1 protein CTD PMID:21132492 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases activity EXP glucoerucin results in increased activity of NQO1 protein CTD PMID:20833222 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
glucoraphanin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP glucoraphanin results in increased expression of CYP1A1 protein CTD PMID:20833222 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP glucoraphanin results in increased expression of CYP1A2 protein CTD PMID:20833222 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression EXP glucoraphanin results in increased expression of CYP1B1 protein CTD PMID:20833222 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP glucoraphanin results in increased expression of EPHX1 protein CTD PMID:21132492 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression
multiple interactions
ISO glucoraphanin analog results in increased expression of GPX2 mRNA; glucoraphanin analog results in increased expression of GPX2 protein
Benzo(a)pyrene inhibits the reaction [glucoraphanin results in increased expression of GPX2 mRNA]; glucobrassicin analog inhibits the reaction [glucoraphanin analog results in increased expression of GPX2 mRNA]
CTD PMID:20868228 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects localization ISO glucoraphanin analog affects the localization of NFE2L2 protein CTD PMID:20868228 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases activity
ISO
EXP
glucobrassicin analog inhibits the reaction [glucoraphanin results in increased activity of NQO1 protein]
glucoraphanin analog results in increased activity of NQO1 protein
CTD PMID:20833222 PMID:20868228 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
isopropyl beta-D-thiogalactopyranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Isopropyl Thiogalactoside results in increased expression of CDKN1A protein CTD PMID:15190207 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
lamivudine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadsb acyl-CoA dehydrogenase, short/branched chain multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ACADSB mRNA CTD PMID:18313992 NCBI chr 1:186,188,939...186,227,796
Ensembl chr 1:186,188,987...186,230,379
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ACSL6 mRNA CTD PMID:18313992 NCBI chr10:38,439,914...38,501,182
Ensembl chr10:38,440,080...38,498,757
JBrowse link
G Acta2 actin alpha 2, smooth muscle decreases expression ISO Lamivudine results in decreased expression of ACTA2 protein CTD PMID:11738102 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ADIPOQ mRNA CTD PMID:16931933 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Aebp1 AE binding protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of AEBP1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of AEBP1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of AEBP1 mRNA CTD PMID:16931933 NCBI chr14:80,738,800...80,748,878
Ensembl chr14:80,738,892...80,748,877
JBrowse link
G Afap1 actin filament associated protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of AFAP1 mRNA CTD PMID:15784690 NCBI chr14:74,743,322...74,856,295
Ensembl chr14:74,743,320...74,856,263
JBrowse link
G Alb albumin affects binding ISO Lamivudine binds to ALB protein CTD PMID:15814459 PMID:16336266 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ALOX5AP mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ALOX5AP mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of ALOX5AP mRNA CTD PMID:16931933 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986
JBrowse link
G Aqp9 aquaporin 9 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of AQP9 mRNA CTD PMID:18313992 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
JBrowse link
G Arpp21 cAMP regulated phosphoprotein 21 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ARPP21 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ARPP21 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of ARPP21 mRNA CTD PMID:16931933 NCBI chr 8:112,034,636...112,199,273
Ensembl chr 8:112,034,642...112,194,297
JBrowse link
G Asic2 acid sensing ion channel subunit 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ASIC2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ASIC2 mRNA CTD PMID:16931933 NCBI chr10:65,870,592...66,940,577
Ensembl chr10:65,870,594...66,940,424
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ASNS mRNA CTD PMID:15784690 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Ass1 argininosuccinate synthase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ASS1 mRNA CTD PMID:15784690 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATF3 mRNA CTD PMID:15784690 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ATP2A2 mRNA CTD PMID:11706060 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5C1 mRNA CTD PMID:18313992 NCBI chr17:68,423,927...68,446,169 JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ATP5G3 mRNA CTD PMID:18313992 NCBI chr 3:58,810,535...58,813,185
Ensembl chr 3:58,810,535...58,814,279
JBrowse link
G Atp5mf ATP synthase membrane subunit f multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5J2 mRNA CTD PMID:18313992 NCBI chr12:9,421,665...9,428,236
Ensembl chr12:9,421,579...9,428,236
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5H mRNA CTD PMID:18313992 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5J mRNA CTD PMID:18313992 NCBI chr11:23,881,594...23,889,581
Ensembl chr11:23,881,592...23,889,119
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ATP5O mRNA CTD PMID:18313992 NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of BCL2 mRNA CTD PMID:18313992 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO Lamivudine results in increased expression of BNIP3L protein CTD PMID:23640862 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G C1r complement C1r multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of C1R mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of C1R mRNA CTD PMID:16931933 NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484
JBrowse link
G C3ar1 complement C3a receptor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of C3AR1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of C3AR1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of C3AR1 mRNA CTD PMID:16931933 NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701
JBrowse link
G Cars cysteinyl-tRNA synthetase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CARS1 mRNA CTD PMID:15784690 NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941
JBrowse link
G Cat catalase multiple interactions EXP [efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in decreased activity of CAT protein CTD PMID:34118364 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression
ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CCNA2 mRNA
Lamivudine results in decreased expression of CCNA2 mRNA
CTD PMID:15784690 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnc cyclin C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CCNC mRNA CTD PMID:15784690 NCBI chr 5:35,266,828...35,284,943
Ensembl chr 5:35,266,823...35,296,584
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CCND1 mRNA CTD PMID:15784690 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 decreases expression
multiple interactions
ISO Lamivudine results in decreased expression of CCND2 mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of CCND2 mRNA
CTD PMID:15784690 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccne2 cyclin E2 multiple interactions
decreases expression
ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CCNE2 mRNA
Lamivudine results in decreased expression of CCNE2 mRNA
CTD PMID:15784690 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Cd36 CD36 molecule multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of CD36 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CD36 mRNA CTD PMID:16931933 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cd44 CD44 molecule (Indian blood group) multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CD44 mRNA CTD PMID:15784690 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd83 CD83 molecule multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CD83 mRNA CTD PMID:15784690 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
JBrowse link
G Cdk7 cyclin-dependent kinase 7 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CDK7 mRNA CTD PMID:15784690 NCBI chr 2:31,840,545...31,865,447
Ensembl chr 2:31,840,558...31,865,383
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression
multiple interactions
ISO Lamivudine results in decreased expression of CDKN1A mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN1A mRNA
CTD PMID:15784690 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN1B mRNA CTD PMID:15784690 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN1C mRNA CTD PMID:15784690 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN2C mRNA CTD PMID:15784690 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
JBrowse link
G Cfd complement factor D multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CFD mRNA CTD PMID:16931933 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
JBrowse link
G Cidec cell death-inducing DFFA-like effector c multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of CIDEC mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CIDEC mRNA CTD PMID:16931933 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
JBrowse link
G Clcn3 chloride voltage-gated channel 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of CLCN3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CLCN3 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of CLCN3 mRNA CTD PMID:16931933 NCBI chr16:29,127,419...29,200,133
Ensembl chr16:29,127,419...29,200,119
JBrowse link
G Clec2dl1 C-type lectin domain family 2 member D-like 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CLEC2I mRNA CTD PMID:16931933 NCBI chr 4:162,263,578...162,274,882
Ensembl chr 4:162,263,639...162,274,880
JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression ISO Lamivudine results in decreased expression of COL3A1 protein CTD PMID:11738102 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COMT mRNA CTD PMID:15784690 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of COX5A mRNA CTD PMID:18313992 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX5B mRNA CTD PMID:18313992 NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052
JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX6A1 mRNA CTD PMID:18313992 NCBI chr12:41,261,983...41,265,037
Ensembl chr12:41,261,967...41,265,041
JBrowse link
G Cox6c cytochrome c oxidase subunit 6C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX6C mRNA CTD PMID:18313992 NCBI chr 7:67,129,265...67,142,001
Ensembl chr 7:67,111,024...67,141,963
JBrowse link
G Cox7c cytochrome c oxidase subunit 7C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX7C mRNA CTD PMID:18313992 NCBI chr 2:16,841,771...16,843,796
Ensembl chr 2:16,840,837...16,843,760
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CPT1A mRNA CTD PMID:18313992 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Crat carnitine O-acetyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CRAT mRNA CTD PMID:18313992 NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255
JBrowse link
G Cul7 cullin 7 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CUL7 mRNA CTD PMID:18313992 NCBI chr 9:14,319,102...14,333,035
Ensembl chr 9:14,319,108...14,332,741
JBrowse link
G Cyb5a cytochrome b5 type A multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CYB5A mRNA CTD PMID:18313992 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CYP11A1 mRNA CTD PMID:18313992 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Dck deoxycytidine kinase multiple interactions ISO DCK protein results in increased phosphorylation of and results in increased activity of Lamivudine CTD PMID:17530837 NCBI chr14:19,305,218...19,326,247
Ensembl chr14:19,305,218...19,326,247
JBrowse link
G Dcn decorin multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of DCN mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of DCN mRNA CTD PMID:16931933 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO Lamivudine results in increased expression of DDIT3 mRNA
[Zidovudine co-treated with Lamivudine] results in increased expression of DDIT3 mRNA
CTD PMID:15784690 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dhfr dihydrofolate reductase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of DHFR mRNA CTD PMID:15784690 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of DIABLO mRNA CTD PMID:18313992 NCBI chr12:33,055,784...33,070,400
Ensembl chr12:33,055,263...33,070,387
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of DLST mRNA CTD PMID:18313992 NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296
JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of DNAJA3 mRNA CTD PMID:18313992 NCBI chr10:10,855,510...10,880,175
Ensembl chr10:10,854,732...10,880,161
JBrowse link
G Dusp3 dual specificity phosphatase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of DUSP3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of DUSP3 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of DUSP3 mRNA CTD PMID:16931933 NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ECHS1 mRNA CTD PMID:18313992 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ECI1 mRNA CTD PMID:18313992 NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
JBrowse link
G Edn1 endothelin 1 multiple interactions
increases secretion
ISO coenzyme Q10 inhibits the reaction [Lamivudine results in increased secretion of EDN1 protein] CTD PMID:23640862 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of EIF4EBP1 mRNA CTD PMID:15784690 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ELOVL3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ELOVL3 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of ELOVL3 mRNA CTD PMID:16931933 NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ESR2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ESR2 mRNA CTD PMID:16931933 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Etv6 ETS variant transcription factor 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ETV6 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ETV6 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of ETV6 mRNA CTD PMID:16931933 NCBI chr 4:166,849,031...167,085,211
Ensembl chr 4:166,847,686...167,084,992
JBrowse link
G Fads2 fatty acid desaturase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FADS2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of FADS2 mRNA CTD PMID:16931933 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
JBrowse link
G Faim Fas apoptotic inhibitory molecule multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of FAIM mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of FAIM mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of FAIM mRNA CTD PMID:16931933 NCBI chr 8:99,543,877...99,569,499
Ensembl chr 8:99,542,405...99,560,562
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [Stavudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FASN mRNA; [Stavudine co-treated with Lamivudine] results in increased expression of FASN mRNA; [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FASN mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of FASN mRNA CTD PMID:11741158 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fdxr ferredoxin reductase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of FDXR mRNA CTD PMID:18313992 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658
JBrowse link
G Fh fumarate hydratase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of FH1 mRNA CTD PMID:18313992 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
JBrowse link
G G0s2 G0/G1switch 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of G0S2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of G0S2 mRNA CTD PMID:16931933 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of G6PC mRNA CTD PMID:16931933 NCBI chr10:86,307,400...86,318,766 JBrowse link
G Ganc glucosidase, alpha; neutral C multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of GANC mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of GANC mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of GANC mRNA CTD PMID:16931933 NCBI chr 3:107,353,369...107,406,104
Ensembl chr 3:107,353,369...107,405,241
JBrowse link
G Gars1 glycyl-tRNA synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of GARS1 mRNA CTD PMID:15784690 NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609
JBrowse link
G Gas1 growth arrest-specific 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of GAS1 mRNA CTD PMID:15784690 NCBI chr17:4,482,014...4,485,155 JBrowse link
G Grhl2 grainyhead-like transcription factor 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of GRHL2 mRNA CTD PMID:16931933 NCBI chr 7:68,400,287...68,530,269
Ensembl chr 7:68,400,477...68,530,258
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of GUCY1B1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of GUCY1B1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of GUCY1B1 mRNA CTD PMID:16931933 NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916
JBrowse link
G Gypa glycophorin A multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased mutagenesis of GYPA gene CTD PMID:17358027 NCBI chr19:27,450,311...27,465,940 JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of HADH mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of HADH mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of HADH mRNA CTD PMID:16931933 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of HADHA mRNA CTD PMID:18313992 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
JBrowse link
G Hax1 HCLS1 associated protein X-1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of HAX1 mRNA CTD PMID:15784690 NCBI chr 2:175,434,242...175,437,926
Ensembl chr 2:175,434,238...175,437,714
JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of HCN1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of HCN1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of HCN1 mRNA CTD PMID:16931933 NCBI chr 2:49,495,771...49,899,702
Ensembl chr 2:49,495,771...49,899,774
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of HMGCS2 mRNA CTD PMID:18313992 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
JBrowse link
G Hrk harakiri, BCL2 interacting protein multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of HRK mRNA CTD PMID:16931933 NCBI chr12:38,387,484...38,409,652 JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of HSD3B2 mRNA CTD PMID:18313992 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852
JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of HSD3B3 mRNA CTD PMID:18313992 NCBI chr 2:186,138,044...186,144,024
Ensembl chr 2:186,138,044...186,144,033
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of IDH2 mRNA CTD PMID:18313992 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of IDH3A mRNA CTD PMID:18313992 NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084
JBrowse link
G Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of IDH3G mRNA CTD PMID:18313992 NCBI chr  X:151,515,244...151,524,175
Ensembl chr  X:151,515,247...151,524,171
JBrowse link
G Ifng interferon gamma increases expression ISO Lamivudine results in increased expression of IFNG protein CTD PMID:16250037 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ikzf4 IKAROS family zinc finger 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of IKZF4 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of IKZF4 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of IKZF4 mRNA CTD PMID:16931933 NCBI chr 7:1,063,283...1,102,940
Ensembl chr 7:1,056,890...1,084,341
JBrowse link
G Il27ra interleukin 27 receptor subunit alpha multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of IL27RA mRNA CTD PMID:15784690 NCBI chr19:24,109,698...24,121,977
Ensembl chr19:24,109,972...24,121,938
JBrowse link
G Inpp5e inositol polyphosphate-5-phosphatase E multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of INPP5E mRNA CTD PMID:18313992 NCBI chr 3:9,216,776...9,229,539
Ensembl chr 3:9,216,776...9,229,450
JBrowse link
G Kcng1 potassium voltage-gated channel modifier subfamily G member 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of KCNG1 mRNA CTD PMID:15784690 NCBI chr 3:156,960,717...156,992,877
Ensembl chr 3:156,973,156...156,992,635
JBrowse link
G Kifc2 kinesin family member C2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of KIFC2 mRNA CTD PMID:16931933 NCBI chr 7:108,380,634...108,388,364
Ensembl chr 7:108,376,011...108,388,484
JBrowse link
G Klf4 Kruppel like factor 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of KLF4 mRNA CTD PMID:15784690 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Klhl28 kelch-like family member 28 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of KLHL28 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of KLHL28 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of KLHL28 mRNA CTD PMID:16931933 NCBI chr 6:82,987,360...83,018,971
Ensembl chr 6:82,990,945...83,016,164
JBrowse link
G Krt7 keratin 7 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of KRT7 mRNA CTD PMID:15784690 NCBI chr 7:132,528,863...132,545,052
Ensembl chr 7:132,528,895...132,545,052
JBrowse link
G Kynu kynureninase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of KYNU mRNA CTD PMID:15784690 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
G Lamb3 laminin subunit beta 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of LAMB3 mRNA CTD PMID:15784690 NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405
JBrowse link
G Lamc2 laminin subunit gamma 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of LAMC2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of LAMC2 mRNA CTD PMID:16931933 NCBI chr13:65,284,664...65,344,200
Ensembl chr13:65,284,664...65,344,200
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of LEF1 mRNA CTD PMID:16931933 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
JBrowse link
G Lep leptin multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of LEP mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of LEP mRNA CTD PMID:16931933 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lpl lipoprotein lipase decreases expression
multiple interactions
ISO Lamivudine results in decreased expression of LPL mRNA
[Stavudine co-treated with Lamivudine co-treated with Indinavir] affects the expression of LPL mRNA; [Stavudine co-treated with Lamivudine co-treated with Nelfinavir] results in decreased expression of LPL mRNA; [Stavudine co-treated with Lamivudine] affects the expression of LPL mRNA; [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of LPL mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of LPL mRNA
CTD PMID:11741158 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Mars1 methionyl-tRNA synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of MARS1 mRNA CTD PMID:15784690 NCBI chr 7:63,121,142...63,138,550
Ensembl chr 7:63,121,142...63,138,495
JBrowse link
G Me1 malic enzyme 1 multiple interactions
increases expression
ISO [Stavudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ME1 mRNA; [Stavudine co-treated with Lamivudine co-treated with Nelfinavir] results in decreased expression of ME1 mRNA; [Stavudine co-treated with Lamivudine] results in increased expression of ME1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ME1 mRNA; [Zidovudine co-treated with Lamivudine] affects the expression of ME1 mRNA
Lamivudine results in increased expression of ME1 mRNA
CTD PMID:11741158 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Mfn1 mitofusin 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of MFN1 mRNA CTD PMID:18313992 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
JBrowse link
G Mfn2 mitofusin 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of MFN2 mRNA CTD PMID:18313992 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mgat4c MGAT4 family, member C multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of MGAT4C mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of MGAT4C mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of MGAT4C mRNA CTD PMID:16931933 NCBI chr 7:36,709,564...37,485,810
Ensembl chr 7:37,260,321...37,474,571
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Lamivudine results in increased expression of MMP1 protein CTD PMID:15309715 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP [efavirenz co-treated with Lamivudine co-treated with Tenofovir] promotes the reaction [[isoniazid, pyrazinamide, rifampin drug combination co-treated with Ethambutol] results in increased activity of MPO protein]; [efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased activity of MPO protein CTD PMID:34118364 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mrap melanocortin 2 receptor accessory protein multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of MRAP mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of MRAP mRNA CTD PMID:16931933 NCBI chr11:29,991,974...30,003,024
Ensembl chr11:29,992,034...30,003,024
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of COX1 mRNA CTD PMID:17526437 PMID:18313992 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of COX2 mRNA CTD PMID:18313992 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX3 mRNA CTD PMID:17526437 PMID:18313992 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ND2 mRNA CTD PMID:18313992 NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942
JBrowse link
G Mt-nd5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ND5 mRNA CTD PMID:17526437 PMID:18313992 NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of MTHFD2 mRNA CTD PMID:15784690 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
JBrowse link
G Myod1 myogenic differentiation 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of MYOD1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of MYOD1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of MYOD1 mRNA CTD PMID:16931933 NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554
JBrowse link
G Nap1l5 nucleosome assembly protein 1-like 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of NAP1L5 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of NAP1L5 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of NAP1L5 mRNA CTD PMID:16931933 NCBI chr 4:88,022,670...88,024,988
Ensembl chr 4:88,022,569...88,024,654
JBrowse link
G Ndufa4 NDUFA4, mitochondrial complex associated multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFA4 mRNA CTD PMID:18313992 NCBI chr 4:40,002,216...40,009,384
Ensembl chr 4:40,002,216...40,023,920
JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFAB1 mRNA CTD PMID:18313992 NCBI chr 1:176,644,696...176,658,131
Ensembl chr 1:176,644,703...176,658,099
JBrowse link
G Ndufaf1 NADH:ubiquinone oxidoreductase complex assembly factor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFAF1 mRNA CTD PMID:18313992 NCBI chr 3:106,639,025...106,650,549
Ensembl chr 3:106,639,851...106,650,212
JBrowse link
G Ndufb3 NADH:ubiquinone oxidoreductase subunit B3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of NDUFB3 mRNA CTD PMID:18313992 NCBI chr 9:60,129,240...60,139,452
Ensembl chr 9:60,129,154...60,139,446
JBrowse link
G Ndufb5 NADH:ubiquinone oxidoreductase subunit B5 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of NDUFB5 mRNA CTD PMID:18313992 NCBI chr 2:115,519,248...115,533,589
Ensembl chr 2:115,519,154...115,533,589
JBrowse link
G Ndufb9 NADH:ubiquinone oxidoreductase subunit B9 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFB9 mRNA CTD PMID:18313992 NCBI chr 7:90,481,013...90,487,360 JBrowse link
G Ndufc1 NADH:ubiquinone oxidoreductase subunit C1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFC1 mRNA CTD PMID:18313992 NCBI chr 2:135,447,067...135,450,950 JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFS1 mRNA CTD PMID:18313992 NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893
JBrowse link
G Niban1 niban apoptosis regulator 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NIBAN1 mRNA CTD PMID:15784690 NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729
JBrowse link
G Noct nocturnin multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of NOCT mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of NOCT mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of NOCT mRNA CTD PMID:16931933 NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
decreases phosphorylation
ISO coenzyme Q10 inhibits the reaction [Lamivudine results in decreased phosphorylation of NOS3 protein] CTD PMID:23640862 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nppa natriuretic peptide A multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of NPPA mRNA CTD PMID:11706060 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nup210 nucleoporin 210 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of NUP210 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of NUP210 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of NUP210 mRNA CTD PMID:16931933 NCBI chr 4:123,511,559...123,609,874
Ensembl chr 4:123,511,559...123,609,874
JBrowse link
G Nxnl2 nucleoredoxin-like 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NXNL2 mRNA CTD PMID:16931933 NCBI chr17:14,031,151...14,035,897
Ensembl chr17:14,031,153...14,036,189
JBrowse link
G Oaz3 ornithine decarboxylase antizyme 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of OAZ3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of OAZ3 mRNA CTD PMID:16931933 NCBI chr 2:182,073,212...182,076,147
Ensembl chr 2:182,073,215...182,082,399
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of OGT mRNA CTD PMID:15784690 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of OPA1 mRNA CTD PMID:18313992 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of OPRL1 mRNA CTD PMID:16931933 NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920
JBrowse link
G Pcdh15 protocadherin related 15 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PCDH15 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PCDH15 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of PCDH15 mRNA CTD PMID:16931933 NCBI chr20:13,997,094...15,496,446
Ensembl chr20:13,963,565...15,494,719
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of PCK2 mRNA CTD PMID:15784690 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of PFKFB3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of PFKFB3 mRNA CTD PMID:16931933 NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125
JBrowse link
G Pgap6 post-glycosylphosphatidylinositol attachment to proteins 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of PGAP6 mRNA CTD PMID:16931933 NCBI chr10:15,138,918...15,151,581
Ensembl chr10:15,138,959...15,148,431
JBrowse link
G Phf6 PHD finger protein 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of PHF6 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of PHF6 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of PHF6 mRNA CTD PMID:16931933 NCBI chr  X:132,656,658...132,699,720
Ensembl chr  X:132,656,672...132,699,127
JBrowse link
G Pidd1 p53-induced death domain protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PIDD1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PIDD1 mRNA CTD PMID:16931933 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699
JBrowse link
G Piwil2 piwi-like RNA-mediated gene silencing 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PIWIL2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PIWIL2 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of PIWIL2 mRNA CTD PMID:16931933 NCBI chr15:45,431,402...45,498,034
Ensembl chr15:45,431,703...45,497,702
JBrowse link
G Porcn porcupine O-acyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PPN mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PPN mRNA CTD PMID:16931933 NCBI chr  X:14,285,864...14,298,481
Ensembl chr  X:14,285,871...14,298,481
JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of POU5F1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of POU5F1 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of POU5F1 mRNA CTD PMID:16931933 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Prdm1 PR/SET domain 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PRDM1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PRDM1 mRNA CTD PMID:16931933 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488
JBrowse link
G Psat1 phosphoserine aminotransferase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of PSAT1 mRNA CTD PMID:15784690 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
JBrowse link
G Rabepk Rab9 effector protein with kelch motifs multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of RABEPK mRNA CTD PMID:15784690 NCBI chr 3:18,061,299...18,083,191
Ensembl chr 3:18,061,574...18,083,191
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of RBL1 mRNA CTD PMID:15784690 NCBI chr 3:145,806,160...145,869,434
Ensembl chr 3:145,807,095...145,869,330
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of RBL2 mRNA CTD PMID:15784690 NCBI chr19:15,876,852...15,923,632
Ensembl chr19:15,876,853...15,923,572
JBrowse link
G Reep6 receptor accessory protein 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of REEP6 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of REEP6 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of REEP6 mRNA CTD PMID:16931933 NCBI chr 7:9,373,927...9,380,845
Ensembl chr 7:9,373,927...9,380,597
JBrowse link
G RGD1562378 histone H4 variant H4-v.1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of H4C9 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of H4C9 mRNA CTD PMID:16931933
G Ripk2 receptor-interacting serine-threonine kinase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of RIPK2 mRNA CTD PMID:15784690 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
JBrowse link
G Rnf151 ring finger protein 151 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of RNF151 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of RNF151 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of RNF151 mRNA CTD PMID:16931933 NCBI chr10:13,742,682...13,747,192
Ensembl chr10:13,742,682...13,745,000
JBrowse link
G Rpain RPA interacting protein multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of RPAIN mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of RPAIN mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of RPAIN mRNA CTD PMID:16931933 NCBI chr10:55,692,410...55,699,910
Ensembl chr10:55,692,417...55,699,933
JBrowse link
G S100a8 S100 calcium binding protein A8 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of S100A8 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of S100A8 mRNA CTD PMID:16931933 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SDHB mRNA CTD PMID:18313992 NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293
JBrowse link
G Serinc1 serine incorporator 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SERINC1 mRNA CTD PMID:16931933 NCBI chr20:36,850,062...36,896,691
Ensembl chr20:36,850,076...36,896,691
JBrowse link
G Sfxn1 sideroflexin 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SFXN1 mRNA CTD PMID:18313992 NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529
JBrowse link
G Sfxn2 sideroflexin 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SFXN2 mRNA CTD PMID:18313992 NCBI chr 1:245,447,014...245,459,312 JBrowse link
G Sfxn4 sideroflexin 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SFXN4 mRNA CTD PMID:18313992 NCBI chr 1:259,976,480...259,998,778
Ensembl chr 1:259,976,481...259,998,754
JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SGPP1 mRNA CTD PMID:18313992 NCBI chr 6:94,425,339...94,446,534
Ensembl chr 6:94,425,339...94,446,534
JBrowse link
G Slc1a4 solute carrier family 1 member 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC1A4 mRNA CTD PMID:15784690 NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418
JBrowse link
G Slc1a5 solute carrier family 1 member 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC1A5 mRNA CTD PMID:15784690 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952
JBrowse link
G Slc22a1 solute carrier family 22 member 1 increases uptake ISO SLC22A1 protein results in increased uptake of Lamivudine CTD PMID:19141712 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc22a2 solute carrier family 22 member 2 increases uptake ISO SLC22A2 protein results in increased uptake of Lamivudine CTD PMID:19141712 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc22a3 solute carrier family 22 member 3 increases uptake ISO SLC22A3 protein results in increased uptake of Lamivudine CTD PMID:19141712 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612
JBrowse link
G Slc25a12 solute carrier family 25 member 12 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SLC25A12 mRNA CTD PMID:18313992 NCBI chr 3:56,098,080...56,192,188
Ensembl chr 3:56,097,269...56,192,100
JBrowse link
G Slc25a15 solute carrier family 25 member 15 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A15 mRNA CTD PMID:18313992 NCBI chr16:69,631,581...69,654,869
Ensembl chr16:69,634,414...69,653,010
JBrowse link
G Slc25a19 solute carrier family 25 member 19 multiple interactions ISO SLC25A19 protein affects the susceptibility to [Stavudine co-treated with Lamivudine co-treated with Indinavir]; SLC25A19 protein affects the susceptibility to [Zidovudine co-treated with Lamivudine co-treated with Indinavir]
[Zidovudine co-treated with Lamivudine] results in decreased expression of SLC25A19 mRNA
CTD PMID:15951836 PMID:18313992 NCBI chr10:100,853,554...100,867,517
Ensembl chr10:100,847,168...100,867,447
JBrowse link
G Slc25a2 solute carrier family 25 member 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SLC25A2 mRNA CTD PMID:18313992 NCBI chr18:29,452,943...29,457,906
Ensembl chr18:29,453,582...29,460,383
JBrowse link
G Slc25a20 solute carrier family 25 member 20 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A20 mRNA CTD PMID:18313992 NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
JBrowse link
G Slc25a29 solute carrier family 25 member 29 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A29 mRNA CTD PMID:18313992 NCBI chr 6:127,742,027...127,752,915
Ensembl chr 6:127,742,033...127,752,940
JBrowse link
G Slc25a3 solute carrier family 25 member 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SLC25A3 mRNA CTD PMID:18313992 NCBI chr 7:25,611,937...25,619,401 JBrowse link
G Slc25a4 solute carrier family 25 member 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A4 mRNA CTD PMID:18313992 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
G Slc28a1 solute carrier family 28 member 1 multiple interactions ISO Lamivudine inhibits the reaction [SLC28A1 protein results in increased transport of Uridine] CTD PMID:10772724 NCBI chr 1:135,079,375...135,122,791
Ensembl chr 1:135,081,385...135,122,464
JBrowse link
G Slc31a1 solute carrier family 31 member 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC31A1 mRNA CTD PMID:15784690 NCBI chr 5:75,814,744...75,844,241
Ensembl chr 5:75,814,743...75,844,228
JBrowse link
G Slc3a2 solute carrier family 3 member 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC3A2 mRNA CTD PMID:15784690 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Slc40a1 solute carrier family 40 member 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC40A1 mRNA CTD PMID:18313992 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
G Slc6a4 solute carrier family 6 member 4 multiple interactions
increases expression
ISO [Lamivudine co-treated with IFNA2 protein] results in increased expression of SLC6A4 mRNA; Lamivudine promotes the reaction [SLC6A4 protein results in increased uptake of Serotonin]; Lamivudine results in increased expression of and results in increased activity of SLC6A4 protein
Lamivudine results in increased expression of SLC6A4 mRNA
CTD PMID:16476009 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link
G Spink5 serine peptidase inhibitor, Kazal type 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of SPINK5 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of SPINK5 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of SPINK5 mRNA CTD PMID:16931933 NCBI chr18:36,264,452...36,333,143
Ensembl chr18:36,264,452...36,332,185
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of STAR mRNA CTD PMID:18313992 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Stc2 stanniocalcin 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of STC2 mRNA CTD PMID:15784690 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973
JBrowse link
G Sub1 SUB1 regulator of transcription multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SUB1 mRNA CTD PMID:16931933 NCBI chr 2:61,005,646...61,020,486
Ensembl chr 2:61,005,666...61,020,436
Ensembl chr 2:61,005,666...61,020,436
JBrowse link
G Tcea1 transcription elongation factor A1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TCEA1 mRNA CTD PMID:15784690 NCBI chr 5:14,631,454...14,668,769
Ensembl chr 5:14,631,454...14,668,745
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression ISO Lamivudine results in decreased expression of TGFB1 protein CTD PMID:15309715 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Timm17b translocase of inner mitochondrial membrane 17b multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TIMM17B mRNA CTD PMID:18313992 NCBI chr  X:14,596,330...14,603,491
Ensembl chr  X:14,594,577...14,603,416
JBrowse link
G Timm23 translocase of inner mitochondrial membrane 23 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TIMM23 mRNA CTD PMID:18313992 NCBI chr16:7,410,308...7,436,392
Ensembl chr16:7,409,688...7,436,379
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 decreases expression ISO Lamivudine results in decreased expression of TIMP1 protein CTD PMID:15309715 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of TIMP2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of TIMP2 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of TIMP2 mRNA CTD PMID:16931933 NCBI chr10:103,541,199...103,590,611 JBrowse link
G Tk2 thymidine kinase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TK2 mRNA CTD PMID:18313992 NCBI chr19:708,859...731,786
Ensembl chr19:708,891...730,924
JBrowse link
G Trib3 tribbles pseudokinase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TRIB3 mRNA CTD PMID:15784690 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Trim42 tripartite motif-containing 42 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of TRIM42 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of TRIM42 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of TRIM42 mRNA CTD PMID:16931933 NCBI chr 8:97,902,349...97,923,268
Ensembl chr 8:97,902,353...97,923,268
JBrowse link
G Twnk twinkle mtDNA helicase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of TWNK mRNA CTD PMID:18313992 NCBI chr 1:243,867,568...243,874,802
Ensembl chr 1:243,868,330...243,874,802
JBrowse link
G Tyms thymidylate synthetase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of TYMS mRNA CTD PMID:15784690 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link
G Tyrp1 tyrosinase-related protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of TYRP1 mRNA CTD PMID:15784690 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516
JBrowse link
G Uqcrb ubiquinol-cytochrome c reductase binding protein multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of UQCRB mRNA CTD PMID:18313992 NCBI chr 7:63,814,784...63,820,150
Ensembl chr 7:63,814,797...63,820,150
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of UQCRC1 mRNA CTD PMID:17526437 PMID:18313992 NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480
JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of UQCRC2 mRNA CTD PMID:18313992 NCBI chr 1:175,167,933...175,198,499
Ensembl chr 1:175,167,894...175,199,453
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of VDAC1 mRNA CTD PMID:18313992 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
G Vdr vitamin D receptor multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of VDR mRNA CTD PMID:11741158 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of VPS4B mRNA CTD PMID:16931933 NCBI chr13:22,907,105...22,932,200
Ensembl chr13:22,907,109...22,932,229
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of WARS1 mRNA CTD PMID:15784690 NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269
JBrowse link
G Wnt10a Wnt family member 10A multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of WNT10A mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of WNT10A mRNA CTD PMID:16931933 NCBI chr 9:76,349,931...76,362,400
Ensembl chr 9:76,349,931...76,362,400
JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of YARS1 mRNA CTD PMID:15784690 NCBI chr 5:141,535,815...141,564,029
Ensembl chr 5:141,535,759...141,563,833
JBrowse link
lincomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mr1 major histocompatibility complex, class I-related affects expression ISO Lincomycin affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 affects expression ISO Lincomycin affects the expression of HLA-E mRNA CTD PMID:25811541 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
neoglucobrassicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases mutagenesis ISO 1-methoxy-3-indolylmethylglucosinolate metabolite results in increased mutagenesis of HPRT1 gene CTD PMID:20846518 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases response to substance ISO SULT1A1 protein results in increased susceptibility to 1-methoxy-3-indolylmethylglucosinolate metabolite CTD PMID:20846518 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
sinigrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr7a3 aldo-keto reductase family 7 member A3 increases activity EXP sinigrin results in increased activity of AKR7A3 protein CTD PMID:9328168 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases activity EXP sinigrin results in increased activity of GSTA5 protein CTD PMID:9328168 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO sinigrin inhibits the reaction [TNF protein affects the localization of RELA protein] CTD PMID:28483571 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO sinigrin inhibits the reaction [TNF protein affects the localization of RELA protein]; sinigrin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; sinigrin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:28483571 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO sinigrin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; sinigrin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:28483571 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19795
    chemical entity 19795
      atom 19794
        nonmetal atom 19681
          sulfur atom 16418
            sulfur molecular entity 16418
              organosulfur compound 15317
                thioacetal 299
                  monothioacetal 268
                    2,4,6-Triethyl-1,3,5-oxadithiane 0
                    S-glycosyl compound + 57
                    emtricitabine + 5
                    lamivudine 213
                    monothioketal + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19795
    subatomic particle 19794
      composite particle 19794
        hadron 19794
          baryon 19794
            nucleon 19794
              atomic nucleus 19794
                atom 19794
                  main group element atom 19693
                    p-block element atom 19693
                      carbon group element atom 19614
                        carbon atom 19604
                          organic molecular entity 19604
                            heteroorganic entity 19273
                              organochalcogen compound 19047
                                organosulfur compound 15317
                                  thioacetal 299
                                    monothioacetal 268
                                      2,4,6-Triethyl-1,3,5-oxadithiane 0
                                      S-glycosyl compound + 57
                                      emtricitabine + 5
                                      lamivudine 213
                                      monothioketal + 0
paths to the root