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ONTOLOGY REPORT - ANNOTATIONS


Term:diphenylpyraline
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Accession:CHEBI:59788 term browser browse the term
Definition:A member of the class of piperidines that is the benzhydryl ether derivative of 1-methyl-4-hydroxypiperidine. A sedating antihistamine, it is used as the hydrochloride for the symptomatic relief of allergic conditions including rhinitis and hay fever, and in pruritic skin disorders. It is also used as the teoclate salt (piprinhydrinate) as an ingredient in compound preparations for the symptomatic relief of coughs and the common cold.
Synonyms:exact_synonym: 4-(diphenylmethoxy)-1-methylpiperidine
 related_synonym: 1-methyl-4-hydroxypiperidine benzhydryl ether;   1-methyl-4-piperidyl benzhydryl ether;   4-(benzhydryloxy)-1-methylpiperidine;   4-(benzhydryloxy)-N-methylpiperidine;   Formula=C19H23NO;   InChI=1S/C19H23NO/c1-20-14-12-18(13-15-20)21-19(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-19H,12-15H2,1H3;   InChIKey=OWQUZNMMYNAXSL-UHFFFAOYSA-N;   SMILES=CN1CCC(CC1)OC(c1ccccc1)c1ccccc1;   difenilpiralina;   diphenylpyralamine;   diphenylpyralinum
 xref: Beilstein:245467 "Beilstein";   CAS:147-20-6 "ChemIDplus";   CAS:147-20-6 "KEGG DRUG";   CAS:147-20-6 "NIST Chemistry WebBook";   DrugBank:DB01146;   Drug_Central:920 "DrugCentral";   HMDB:HMDB0015277;   KEGG:D07862;   LINCS:LSM-5385
 xref_mesh: MESH:C009871
 xref: PMID:14039 "Europe PMC";   PMID:15627433 "Europe PMC";   PMID:22445882 "Europe PMC";   Patent:US2479843;   Reaxys:245467 "Reaxys";   Wikipedia:Diphenylpyraline


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diphenylpyraline term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hrh1 histamine receptor H 1 JBrowse link 4 146,374,596 146,458,148 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19662
    role 19606
      biological role 19604
        pharmacological role 18687
          antagonist 15809
            histamine antagonist 4484
              H1-receptor antagonist 4007
                diphenylpyraline 2
                  diphenylpyraline hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  main group element atom 19539
                    main group molecular entity 19539
                      s-block molecular entity 19322
                        hydrogen molecular entity 19312
                          hydrides 18241
                            inorganic hydride 17110
                              pnictogen hydride 17068
                                nitrogen hydride 16889
                                  azane 16565
                                    ammonia 16562
                                      organic amino compound 16561
                                        tertiary amino compound 8525
                                          tertiary amine 599
                                            diphenylpyraline 2
                                              diphenylpyraline hydrochloride 0
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