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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chromatographic reagent
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Accession:CHEBI:59745 term browser browse the term
Definition:A reagent used to improve selectivity in chromatographic analyses or separations, e.g. by formation of a derivative or by modification of the mobile phase.
Synonyms:related_synonym: derivatising reagents;   derivatizing reagent;   derivatizing reagents


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1-fluoro-2,4-dinitrobenzene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin increases expression ISO Dinitrofluorobenzene results in increased expression of ADM mRNA CTD PMID:23999411 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Akirin2 akirin 2 increases expression ISO Dinitrofluorobenzene results in increased expression of AKIRIN2 mRNA CTD PMID:23999411 NCBI chr 5:49,108,231...49,122,566
Ensembl chr 5:49,108,220...49,122,568
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO Dinitrofluorobenzene results in increased phosphorylation of AKT1 protein CTD PMID:23445166 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) increases expression ISO Dinitrofluorobenzene results in increased expression of AQP3 mRNA CTD PMID:21362464 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
JBrowse link
G Arg2 arginase 2 increases expression ISO Dinitrofluorobenzene results in increased expression of ARG2 mRNA CTD PMID:23999411 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Dinitrofluorobenzene results in increased expression of ATF3 mRNA CTD PMID:23999411 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 increases expression ISO Dinitrofluorobenzene results in increased expression of BABAM2 mRNA CTD PMID:23999411 NCBI chr 6:24,369,021...24,833,335
Ensembl chr 6:24,369,022...24,833,951
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO [CCL2 protein results in increased expression of CCR2 protein] which affects the susceptibility to Dinitrofluorobenzene
Dinitrofluorobenzene results in increased expression of CCL2 mRNA
CTD PMID:15719370 PMID:21362464 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO Dinitrofluorobenzene results in increased expression of CCL3 mRNA CTD PMID:15719370 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO Dinitrofluorobenzene results in increased expression of CCL4 mRNA
Dinitrofluorobenzene results in increased expression of CCL4 protein
CTD PMID:15719370 PMID:18353026 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO Dinitrofluorobenzene results in increased expression of CCL5 mRNA; Dinitrofluorobenzene results in increased expression of CCL5 protein CTD PMID:15719370 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccne2 cyclin E2 increases expression ISO Dinitrofluorobenzene results in increased expression of CCNE2 mRNA CTD PMID:23999411 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression
multiple interactions
ISO Dinitrofluorobenzene results in increased expression of CCR2 mRNA
[CCL2 protein results in increased expression of CCR2 protein] which affects the susceptibility to Dinitrofluorobenzene
CTD PMID:21362464 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Ccr6 C-C motif chemokine receptor 6 decreases expression ISO Dinitrofluorobenzene results in decreased expression of CCR6 protein CTD PMID:15924226 NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603
JBrowse link
G Cd83 CD83 molecule increases expression ISO Dinitrofluorobenzene results in increased expression of CD83 protein CTD PMID:21362464 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
JBrowse link
G Cd86 CD86 molecule increases expression ISO Dinitrofluorobenzene results in increased expression of CD86 protein CTD PMID:21362464 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression ISO Dinitrofluorobenzene affects the expression of CREB1 mRNA CTD PMID:20385217 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crem cAMP responsive element modulator increases expression ISO Dinitrofluorobenzene results in increased expression of CREM mRNA CTD PMID:21362464 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
decreases expression
ISO Dinitrofluorobenzene results in increased expression of CXCL10 mRNA; Dinitrofluorobenzene results in increased expression of CXCL10 protein
Dinitrofluorobenzene results in decreased expression of CXCL10 mRNA
CTD PMID:15719370 PMID:23445166 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO Dinitrofluorobenzene results in increased expression of CXCL1 mRNA CTD PMID:15719370 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression ISO Dinitrofluorobenzene results in decreased expression of CXCR4 protein CTD PMID:15924226 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cytip cytohesin 1 interacting protein increases expression ISO Dinitrofluorobenzene results in increased expression of CYTIP mRNA CTD PMID:21362464 NCBI chr 3:42,698,058...42,774,955
Ensembl chr 3:42,698,768...42,725,993
JBrowse link
G Dhrs2 dehydrogenase/reductase 2 increases expression ISO Dinitrofluorobenzene results in increased expression of DHRS2 mRNA CTD PMID:23999411 NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Dinitrofluorobenzene results in increased expression of DNAJB4 mRNA CTD PMID:23999411 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
JBrowse link
G Eif1 eukaryotic translation initiation factor 1 increases expression ISO Dinitrofluorobenzene results in increased expression of EIF1 mRNA CTD PMID:23999411 NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327
JBrowse link
G Epc1 enhancer of polycomb homolog 1 increases expression ISO Dinitrofluorobenzene results in increased expression of EPC1 mRNA CTD PMID:23999411 NCBI chr17:54,503,358...54,594,444
Ensembl chr17:54,503,358...54,594,425
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Dinitrofluorobenzene results in increased expression of FOSB mRNA CTD PMID:23999411 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Dinitrofluorobenzene results in increased expression of GCLC mRNA CTD PMID:23999411 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Dinitrofluorobenzene results in increased expression of GCLM mRNA CTD PMID:23999411 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G H2ax H2A.X variant histone increases expression ISO Dinitrofluorobenzene results in increased expression of H2AX mRNA CTD PMID:23999411 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Dinitrofluorobenzene results in increased expression of HMOX1 mRNA CTD PMID:23445166 PMID:25091725 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO Dinitrofluorobenzene results in increased expression of HSPA1A mRNA CTD PMID:23999411
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO Dinitrofluorobenzene results in increased expression of HSPH1 mRNA CTD PMID:23999411 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression
ISO BIRB 796 inhibits the reaction [Dinitrofluorobenzene results in increased expression of ICAM1 protein] CTD PMID:19427879 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
ISO Dinitrofluorobenzene results in increased expression of IFNG mRNA; Dinitrofluorobenzene results in increased expression of IFNG protein
oleanolic acid 3-acetate inhibits the reaction [Dinitrofluorobenzene results in increased expression of IFNG mRNA]
CTD PMID:11243917 PMID:11244134 PMID:23499868 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il10 interleukin 10 increases expression ISO Dinitrofluorobenzene results in increased expression of IL10 mRNA CTD PMID:11243917 PMID:23499868 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il12b interleukin 12B increases expression ISO Dinitrofluorobenzene results in increased expression of IL12B mRNA CTD PMID:11708898 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il15ra interleukin 15 receptor subunit alpha increases response to substance ISO IL15RA protein results in increased susceptibility to Dinitrofluorobenzene CTD PMID:15719370 NCBI chr17:66,802,300...66,831,973
Ensembl chr17:66,802,334...66,832,278
JBrowse link
G Il17a interleukin 17A increases expression
multiple interactions
ISO Dinitrofluorobenzene results in increased expression of IL17A mRNA
oleanolic acid 3-acetate inhibits the reaction [Dinitrofluorobenzene results in increased expression of IL17A mRNA]
CTD PMID:23499868 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il17f interleukin 17F increases expression ISO Dinitrofluorobenzene results in increased expression of IL17F mRNA CTD PMID:23445166 NCBI chr 9:23,190,094...23,201,482
Ensembl chr 9:23,190,100...23,201,482
JBrowse link
G Il1a interleukin 1 alpha increases expression
affects secretion
ISO Dinitrofluorobenzene results in increased expression of IL1A mRNA; Dinitrofluorobenzene results in increased expression of IL1A protein
Dinitrofluorobenzene affects the secretion of IL1A protein
CTD PMID:8006454 PMID:12781210 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il2 interleukin 2 increases expression ISO Dinitrofluorobenzene results in increased expression of IL2 mRNA; Dinitrofluorobenzene results in increased expression of IL2 protein CTD PMID:11244134 PMID:22381623 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4 interleukin 4 increases expression ISO Dinitrofluorobenzene results in increased expression of IL4 mRNA CTD PMID:23499868 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il4r interleukin 4 receptor increases expression ISO Dinitrofluorobenzene results in increased expression of IL4RA protein CTD PMID:22381623 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G LOC686035 similar to heat shock 70kDa protein 6 (HSP70B) increases expression ISO Dinitrofluorobenzene results in increased expression of HSPA6 mRNA CTD PMID:23999411 NCBI chr13:83,271,340...83,275,267 JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Dinitrofluorobenzene results in increased expression of MAFF mRNA CTD PMID:23999411 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO Dinitrofluorobenzene results in increased phosphorylation of MAPK1 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK1 protein]
CTD PMID:27129696 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation ISO Dinitrofluorobenzene results in increased phosphorylation of MAPK14 protein CTD PMID:19427879 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO Dinitrofluorobenzene results in increased phosphorylation of MAPK3 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK3 protein]
CTD PMID:27129696 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions
ISO Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein]
CTD PMID:27129696 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation
multiple interactions
ISO Dinitrofluorobenzene results in increased phosphorylation of MAPK9 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK9 protein]
CTD PMID:27129696 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mif macrophage migration inhibitory factor increases expression ISO Dinitrofluorobenzene results in increased expression of MIF mRNA CTD PMID:11244134 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Mxd1 max dimerization protein 1 increases expression ISO Dinitrofluorobenzene results in increased expression of MXD1 mRNA CTD PMID:21362464 NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression ISO Dinitrofluorobenzene results in increased expression of NAMPT mRNA CTD PMID:21362464 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression ISO Dinitrofluorobenzene results in increased expression of NFE2L2 protein CTD PMID:19427879 PMID:26022718 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression ISO Dinitrofluorobenzene results in decreased expression of NFKB1 mRNA CTD PMID:20385217 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Dinitrofluorobenzene results in increased expression of NQO1 mRNA CTD PMID:23445166 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 increases expression ISO Dinitrofluorobenzene results in increased expression of NR2F2 mRNA CTD PMID:23999411 NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 increases expression ISO Dinitrofluorobenzene results in increased expression of NTRK2 mRNA CTD PMID:23999411 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
JBrowse link
G Peg10 paternally expressed 10 increases expression ISO Dinitrofluorobenzene results in increased expression of PEG10 mRNA CTD PMID:23999411 NCBI chr 4:32,842,394...32,855,641 JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Dinitrofluorobenzene results in increased expression of PMAIP1 mRNA CTD PMID:23999411 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
ISO Dinitrofluorobenzene results in increased expression of PTGS2 mRNA; Dinitrofluorobenzene results in increased expression of PTGS2 protein
[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which affects the susceptibility to Dinitrofluorobenzene
CTD PMID:21362464 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptx3 pentraxin 3 increases expression ISO Dinitrofluorobenzene results in increased expression of PTX3 mRNA CTD PMID:23999411 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
JBrowse link
G Rgs16 regulator of G-protein signaling 16 increases expression ISO Dinitrofluorobenzene results in increased expression of RGS16 mRNA CTD PMID:23999411 NCBI chr13:65,887,788...65,891,232
Ensembl chr13:65,887,530...65,892,857
JBrowse link
G Slc2a3 solute carrier family 2 member 3 increases expression ISO Dinitrofluorobenzene results in increased expression of SLC2A3 mRNA CTD PMID:21362464 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions
increases response to substance
ISO Trinitrobenzenesulfonic Acid promotes the reaction [SPP1 protein results in increased susceptibility to Dinitrofluorobenzene] CTD PMID:14555839 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Taf7 TATA-box binding protein associated factor 7 increases expression ISO Dinitrofluorobenzene results in increased expression of TAF7 mRNA CTD PMID:23999411 NCBI chr18:29,459,937...29,462,086
Ensembl chr18:29,452,943...29,462,134
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO Dinitrofluorobenzene results in increased expression of TGFB1 mRNA CTD PMID:11244134 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Ticam2 toll-like receptor adaptor molecule 2 increases expression ISO Dinitrofluorobenzene results in increased expression of TICAM2 mRNA CTD PMID:23999411 NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462
JBrowse link
G Tnf tumor necrosis factor affects expression
multiple interactions
increases expression
ISO Dinitrofluorobenzene affects the expression of TNF mRNA
oleanolic acid 3-acetate inhibits the reaction [Dinitrofluorobenzene results in increased expression of TNF mRNA]
CTD PMID:20385217 PMID:23499868 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b increases expression ISO Dinitrofluorobenzene results in increased expression of TNFRSF10A mRNA CTD PMID:23999411 NCBI chr15:44,839,818...44,867,582 JBrowse link
G Trib1 tribbles pseudokinase 1 increases expression ISO Dinitrofluorobenzene results in increased expression of TRIB1 mRNA CTD PMID:23999411 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731
JBrowse link
G Trim27 tripartite motif-containing 27 increases expression ISO Dinitrofluorobenzene results in increased expression of TRIM27 mRNA CTD PMID:23999411 NCBI chr17:43,538,282...43,550,633
Ensembl chr17:43,538,285...43,550,643
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Dinitrofluorobenzene results in increased expression of TXNRD1 mRNA CTD PMID:23445166 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 increases expression ISO Dinitrofluorobenzene results in increased expression of XCL1 mRNA CTD PMID:15719370 NCBI chr13:77,248,865...77,252,308
Ensembl chr13:77,248,717...77,252,329
JBrowse link
G Zfp870 zinc finger protein 870 increases expression ISO Dinitrofluorobenzene results in increased expression of ZNF670 mRNA CTD PMID:23999411 NCBI chr 7:11,990,146...12,003,813
Ensembl chr 7:11,990,148...12,003,813
JBrowse link
G Zxdb zinc finger, X-linked, duplicated B increases expression ISO Dinitrofluorobenzene results in increased expression of ZXDB mRNA CTD PMID:23999411 NCBI chr  X:59,760,871...59,766,310
Ensembl chr  X:59,763,210...59,765,903
JBrowse link
perfluorobutyric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha increases expression EXP perfluorobutyric acid analog results in increased expression of ACACA mRNA CTD PMID:21878386 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression EXP perfluorobutyric acid results in increased expression of ACOT1 mRNA CTD PMID:19407336 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression EXP
ISO
perfluorobutyric acid analog results in increased expression of ACOX1 mRNA; perfluorobutyric acid results in increased expression of ACOX1 mRNA CTD PMID:19359353 PMID:19407336 PMID:21878386 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Actb actin, beta decreases expression ISO perfluorobutyric acid results in decreased expression of ACTB mRNA CTD PMID:23567314 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Angptl4 angiopoietin-like 4 decreases expression ISO perfluorobutyric acid results in decreased expression of ANGPTL4 mRNA CTD PMID:23567314 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Apoa1 apolipoprotein A1 decreases expression EXP perfluorobutyric acid analog results in decreased expression of APOA1 mRNA CTD PMID:21878386 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa4 apolipoprotein A4 affects expression EXP perfluorobutyric acid affects the expression of APOA4 mRNA CTD PMID:22071372 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Ar androgen receptor multiple interactions ISO perfluorobutyric acid promotes the reaction [Dihydrotestosterone results in increased activity of AR protein] CTD PMID:29601859 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A decreases expression ISO perfluorobutyric acid results in decreased expression of CPT1A mRNA CTD PMID:23567314 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B increases expression ISO perfluorobutyric acid results in increased expression of CPT1B mRNA CTD PMID:23567314 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression EXP
ISO
perfluorobutyric acid analog results in decreased expression of CYP1A1 mRNA
perfluorobutyric acid results in decreased expression of CYP1A1 mRNA
CTD PMID:21878386 PMID:23567314 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP perfluorobutyric acid analog results in increased expression of CYP2B2 mRNA CTD PMID:21878386 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP perfluorobutyric acid analog results in increased expression of CYP3A23-3A1 mRNA CTD PMID:21878386 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP perfluorobutyric acid analog results in increased expression of CYP4A1 mRNA; perfluorobutyric acid results in increased expression of CYP4A1 mRNA CTD PMID:19407336 PMID:21878386 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression EXP perfluorobutyric acid analog results in increased expression of CYP7A1 mRNA CTD PMID:21878386 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases expression EXP perfluorobutyric acid analog results in decreased expression of DIO1 mRNA CTD PMID:21878386 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression ISO perfluorobutyric acid results in increased expression of EHHADH mRNA CTD PMID:23567314 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
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G Fabp1 fatty acid binding protein 1 increases expression ISO perfluorobutyric acid results in increased expression of FABP1 mRNA CTD PMID:23567314 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fasn fatty acid synthase increases expression EXP perfluorobutyric acid analog results in increased expression of FASN mRNA CTD PMID:21878386 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression EXP perfluorobutyric acid results in decreased expression of FDFT1 mRNA CTD PMID:22071372 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression EXP perfluorobutyric acid results in decreased expression of HADHA mRNA CTD PMID:22071372 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta decreases expression EXP perfluorobutyric acid results in decreased expression of HADHB mRNA CTD PMID:22071372 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
JBrowse link
G Hhex hematopoietically expressed homeobox decreases expression EXP perfluorobutyric acid results in decreased expression of HHEX mRNA CTD PMID:22071372 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042
JBrowse link
G Mal mal, T-cell differentiation protein increases expression EXP perfluorobutyric acid analog results in increased expression of MAL mRNA CTD PMID:21878386 NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression ISO perfluorobutyric acid results in decreased expression of NOS2 mRNA CTD PMID:23567314 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO perfluorobutyric acid results in increased activity of NR1I2 protein CTD PMID:28115241 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Pax8 paired box 8 increases expression EXP perfluorobutyric acid results in increased expression of PAX8 mRNA CTD PMID:22071372 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression EXP perfluorobutyric acid analog results in increased expression of PCNA mRNA CTD PMID:21878386 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO perfluorobutyric acid results in increased expression of PDK4 mRNA CTD PMID:23567314 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Plin2 perilipin 2 increases expression ISO perfluorobutyric acid results in increased expression of PLIN2 mRNA CTD PMID:23567314 NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP perfluorobutyric acid analog results in increased expression of POR mRNA CTD PMID:21878386 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases activity
affects response to substance
ISO perfluorobutyric acid results in increased activity of PPARA protein
PPARA protein affects the susceptibility to perfluorobutyric acid
CTD PMID:19359353 PMID:23391484 PMID:28857218 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases activity ISO perfluorobutyric acid results in increased activity of PPARG protein CTD PMID:24998974 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 multiple interactions ISO perfluorobutyric acid binds to and results in decreased activity of PTPN11 protein CTD PMID:27572461 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO perfluorobutyric acid results in increased expression of SCD1 mRNA CTD PMID:23567314 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Thrsp thyroid hormone responsive increases expression EXP perfluorobutyric acid analog results in increased expression of THRSP mRNA CTD PMID:21878386 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
JBrowse link
G Ttr transthyretin multiple interactions ISO perfluorobutyric acid affects the reaction [Thyroxine binds to TTR protein] CTD PMID:27528273 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
JBrowse link
G Txnip thioredoxin interacting protein decreases expression ISO perfluorobutyric acid results in decreased expression of TXNIP mRNA CTD PMID:23567314 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP perfluorobutyric acid analog results in increased expression of UGT1A1 mRNA CTD PMID:21878386 NCBI chr 9:88,801,344...88,808,465 JBrowse link

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  CHEBI ontology 19812
    role 19761
      application 19471
        reagent 17474
          chromatographic reagent 116
            1-fluoro-2,4-dinitrobenzene 77
            N,N-dimethylformamide dimethyl acetal 0
            N,O-bis(trimethylsilyl)trifluoroacetamide 0
            N-(tert-butyldimethylsilyl)-N-methyltrifluoroacetamide 0
            N-(trimethylsilyl)diethylamine 0
            N-methyl-N-(trimethylsilyl)trifluoroacetamide 0
            N-trimethylsilylimidazole 0
            chlorotrimethylsilane 0
            heptafluorobutyric anhydride 0
            hexamethyldisilazane 0
            pentafluorobenzoyl chloride 0
            perfluorobutyric acid 39
            tert-butyldimethylsilyl chloride 0
            trimethylphenylammonium hydroxide 0
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