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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chromatographic reagent
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Accession:CHEBI:59745 term browser browse the term
Definition:A reagent used to improve selectivity in chromatographic analyses or separations, e.g. by formation of a derivative or by modification of the mobile phase.
Synonyms:related_synonym: derivatising reagents;   derivatizing reagent;   derivatizing reagents


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1-fluoro-2,4-dinitrobenzene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin increases expression ISO Dinitrofluorobenzene results in increased expression of ADM mRNA CTD PMID:23999411 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Akirin2 akirin 2 increases expression ISO Dinitrofluorobenzene results in increased expression of AKIRIN2 mRNA CTD PMID:23999411 NCBI chr 5:50,001,945...50,016,544
Ensembl chr 5:50,002,184...50,016,539
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO Dinitrofluorobenzene results in increased phosphorylation of AKT1 protein CTD PMID:23445166 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) increases expression ISO Dinitrofluorobenzene results in increased expression of AQP3 mRNA CTD PMID:21362464 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Arg2 arginase 2 increases expression ISO Dinitrofluorobenzene results in increased expression of ARG2 mRNA CTD PMID:23999411 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Dinitrofluorobenzene results in increased expression of ATF3 mRNA CTD PMID:23999411 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 increases expression ISO Dinitrofluorobenzene results in increased expression of BABAM2 mRNA CTD PMID:23999411 NCBI chr 6:25,666,654...26,135,888
Ensembl chr 6:25,666,655...26,051,229
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO [CCL2 protein results in increased expression of CCR2 protein] which affects the susceptibility to Dinitrofluorobenzene
Dinitrofluorobenzene results in increased expression of CCL2 mRNA
CTD PMID:15719370, PMID:21362464 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO Dinitrofluorobenzene results in increased expression of CCL3 mRNA CTD PMID:15719370 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO Dinitrofluorobenzene results in increased expression of CCL4 mRNA
Dinitrofluorobenzene results in increased expression of CCL4 protein
CTD PMID:15719370, PMID:18353026 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO Dinitrofluorobenzene results in increased expression of CCL5 mRNA; Dinitrofluorobenzene results in increased expression of CCL5 protein CTD PMID:15719370 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccne2 cyclin E2 increases expression ISO Dinitrofluorobenzene results in increased expression of CCNE2 mRNA CTD PMID:23999411 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression
multiple interactions
ISO Dinitrofluorobenzene results in increased expression of CCR2 mRNA
[CCL2 protein results in increased expression of CCR2 protein] which affects the susceptibility to Dinitrofluorobenzene
CTD PMID:21362464
G Ccr6 C-C motif chemokine receptor 6 decreases expression ISO Dinitrofluorobenzene results in decreased expression of CCR6 protein CTD PMID:15924226 NCBI chr 1:53,063,380...53,087,519
Ensembl chr 1:53,065,025...53,087,474
JBrowse link
G Cd83 CD83 molecule increases expression ISO Dinitrofluorobenzene results in increased expression of CD83 protein CTD PMID:21362464 NCBI chr17:24,416,651...24,435,790
Ensembl chr17:24,416,651...24,435,790
JBrowse link
G Cd86 CD86 molecule increases expression ISO Dinitrofluorobenzene results in increased expression of CD86 protein CTD PMID:21362464 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression ISO Dinitrofluorobenzene affects the expression of CREB1 mRNA CTD PMID:20385217 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crem cAMP responsive element modulator increases expression ISO Dinitrofluorobenzene results in increased expression of CREM mRNA CTD PMID:21362464 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
decreases expression
ISO Dinitrofluorobenzene results in increased expression of CXCL10 mRNA; Dinitrofluorobenzene results in increased expression of CXCL10 protein
Dinitrofluorobenzene results in decreased expression of CXCL10 mRNA
CTD PMID:15719370, PMID:23445166 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO Dinitrofluorobenzene results in increased expression of CXCL1 mRNA CTD PMID:15719370 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression ISO Dinitrofluorobenzene results in decreased expression of CXCR4 protein CTD PMID:15924226 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cytip cytohesin 1 interacting protein increases expression ISO Dinitrofluorobenzene results in increased expression of CYTIP mRNA CTD PMID:21362464 NCBI chr 3:44,150,494...44,225,723
Ensembl chr 3:44,150,992...44,177,689
JBrowse link
G Dhrs2 dehydrogenase/reductase 2 increases expression ISO Dinitrofluorobenzene results in increased expression of DHRS2 mRNA CTD PMID:23999411 NCBI chr15:33,876,701...33,891,559
Ensembl chr15:33,885,106...33,891,539
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Dinitrofluorobenzene results in increased expression of DNAJB4 mRNA CTD PMID:23999411 NCBI chr 2:257,394,692...257,425,344
Ensembl chr 2:257,394,818...257,425,242
JBrowse link
G Eif1 eukaryotic translation initiation factor 1 increases expression ISO Dinitrofluorobenzene results in increased expression of EIF1 mRNA CTD PMID:23999411 NCBI chr10:88,227,455...88,229,546
Ensembl chr10:88,227,360...88,229,765
JBrowse link
G Epc1 enhancer of polycomb homolog 1 increases expression ISO Dinitrofluorobenzene results in increased expression of EPC1 mRNA CTD PMID:23999411 NCBI chr17:57,303,968...57,394,975
Ensembl chr17:57,304,933...57,394,985
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Dinitrofluorobenzene results in increased expression of FOSB mRNA CTD PMID:23999411 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Dinitrofluorobenzene results in increased expression of GCLC mRNA CTD PMID:23999411 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Dinitrofluorobenzene results in increased expression of GCLM mRNA CTD PMID:23999411 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G H2ax H2A.X variant histone increases expression ISO Dinitrofluorobenzene results in increased expression of H2AX mRNA CTD PMID:23999411 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Dinitrofluorobenzene results in increased expression of HMOX1 mRNA CTD PMID:23445166, PMID:25091725 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO Dinitrofluorobenzene results in increased expression of HSPA1A mRNA CTD PMID:23999411 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO Dinitrofluorobenzene results in increased expression of HSPH1 mRNA CTD PMID:23999411 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression
ISO BIRB 796 inhibits the reaction [Dinitrofluorobenzene results in increased expression of ICAM1 protein] CTD PMID:19427879 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
ISO Dinitrofluorobenzene results in increased expression of IFNG mRNA; Dinitrofluorobenzene results in increased expression of IFNG protein
oleanolic acid 3-acetate inhibits the reaction [Dinitrofluorobenzene results in increased expression of IFNG mRNA]
CTD PMID:11243917, PMID:11244134, PMID:23499868 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il10 interleukin 10 increases expression ISO Dinitrofluorobenzene results in increased expression of IL10 mRNA CTD PMID:11243917, PMID:23499868 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12b interleukin 12B increases expression ISO Dinitrofluorobenzene results in increased expression of IL12B mRNA CTD PMID:11708898 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il15ra interleukin 15 receptor subunit alpha increases response to substance ISO IL15RA protein results in increased susceptibility to Dinitrofluorobenzene CTD PMID:15719370 NCBI chr17:70,451,861...70,481,838
Ensembl chr17:70,451,411...70,481,750
JBrowse link
G Il17a interleukin 17A increases expression
multiple interactions
ISO Dinitrofluorobenzene results in increased expression of IL17A mRNA
oleanolic acid 3-acetate inhibits the reaction [Dinitrofluorobenzene results in increased expression of IL17A mRNA]
CTD PMID:23499868 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il17f interleukin 17F increases expression ISO Dinitrofluorobenzene results in increased expression of IL17F mRNA CTD PMID:23445166 NCBI chr 9:26,885,702...26,897,219
Ensembl chr 9:26,885,708...26,897,219
JBrowse link
G Il1a interleukin 1 alpha increases expression
affects secretion
ISO Dinitrofluorobenzene results in increased expression of IL1A mRNA; Dinitrofluorobenzene results in increased expression of IL1A protein
Dinitrofluorobenzene affects the secretion of IL1A protein
CTD PMID:8006454, PMID:12781210 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il2 interleukin 2 increases expression ISO Dinitrofluorobenzene results in increased expression of IL2 mRNA; Dinitrofluorobenzene results in increased expression of IL2 protein CTD PMID:11244134, PMID:22381623 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il4 interleukin 4 increases expression ISO Dinitrofluorobenzene results in increased expression of IL4 mRNA CTD PMID:23499868 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il4r interleukin 4 receptor increases expression ISO Dinitrofluorobenzene results in increased expression of IL4RA protein CTD PMID:22381623 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Dinitrofluorobenzene results in increased expression of MAFF mRNA CTD PMID:23999411 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO Dinitrofluorobenzene results in increased phosphorylation of MAPK1 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK1 protein]
CTD PMID:27129696 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation ISO Dinitrofluorobenzene results in increased phosphorylation of MAPK14 protein CTD PMID:19427879 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO Dinitrofluorobenzene results in increased phosphorylation of MAPK3 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK3 protein]
CTD PMID:27129696 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions
ISO Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein]
CTD PMID:27129696 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation
multiple interactions
ISO Dinitrofluorobenzene results in increased phosphorylation of MAPK9 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK9 protein]
CTD PMID:27129696 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mif macrophage migration inhibitory factor increases expression ISO Dinitrofluorobenzene results in increased expression of MIF mRNA CTD PMID:11244134 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mxd1 max dimerization protein 1 increases expression ISO Dinitrofluorobenzene results in increased expression of MXD1 mRNA CTD PMID:21362464 NCBI chr 4:118,451,752...118,472,150
Ensembl chr 4:118,449,882...118,472,179
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression ISO Dinitrofluorobenzene results in increased expression of NAMPT mRNA CTD PMID:21362464 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression ISO Dinitrofluorobenzene results in increased expression of NFE2L2 protein CTD PMID:19427879, PMID:26022718 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression ISO Dinitrofluorobenzene results in decreased expression of NFKB1 mRNA CTD PMID:20385217 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Dinitrofluorobenzene results in increased expression of NQO1 mRNA CTD PMID:23445166 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 increases expression ISO Dinitrofluorobenzene results in increased expression of NR2F2 mRNA CTD PMID:23999411 NCBI chr 1:131,447,671...131,465,749
Ensembl chr 1:131,448,447...131,460,473
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 increases expression ISO Dinitrofluorobenzene results in increased expression of NTRK2 mRNA CTD PMID:23999411 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Peg10 paternally expressed 10 increases expression ISO Dinitrofluorobenzene results in increased expression of PEG10 mRNA CTD PMID:23999411 NCBI chr 4:29,795,524...29,804,517 JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Dinitrofluorobenzene results in increased expression of PMAIP1 mRNA CTD PMID:23999411 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
ISO Dinitrofluorobenzene results in increased expression of PTGS2 mRNA; Dinitrofluorobenzene results in increased expression of PTGS2 protein
[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which affects the susceptibility to Dinitrofluorobenzene
CTD PMID:21362464 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptx3 pentraxin 3 increases expression ISO Dinitrofluorobenzene results in increased expression of PTX3 mRNA CTD PMID:23999411 NCBI chr 2:158,097,843...158,103,653
Ensembl chr 2:158,097,843...158,103,653
JBrowse link
G Rgs16 regulator of G-protein signaling 16 increases expression ISO Dinitrofluorobenzene results in increased expression of RGS16 mRNA CTD PMID:23999411 NCBI chr13:71,163,411...71,185,147
Ensembl chr13:71,179,910...71,185,216
JBrowse link
G Slc2a3 solute carrier family 2 member 3 increases expression ISO Dinitrofluorobenzene results in increased expression of SLC2A3 mRNA CTD PMID:21362464 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions
increases response to substance
ISO Trinitrobenzenesulfonic Acid promotes the reaction [SPP1 protein results in increased susceptibility to Dinitrofluorobenzene] CTD PMID:14555839 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Taf7 TATA-box binding protein associated factor 7 increases expression ISO Dinitrofluorobenzene results in increased expression of TAF7 mRNA CTD PMID:23999411 NCBI chr18:30,779,149...30,781,297
Ensembl chr18:30,779,150...30,781,292
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO Dinitrofluorobenzene results in increased expression of TGFB1 mRNA CTD PMID:11244134 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Ticam2 toll-like receptor adaptor molecule 2 increases expression ISO Dinitrofluorobenzene results in increased expression of TICAM2 mRNA CTD PMID:23999411 NCBI chr18:40,555,106...40,572,569
Ensembl chr18:40,555,106...40,572,241
JBrowse link
G Tnf tumor necrosis factor affects expression
multiple interactions
increases expression
ISO Dinitrofluorobenzene affects the expression of TNF mRNA
oleanolic acid 3-acetate inhibits the reaction [Dinitrofluorobenzene results in increased expression of TNF mRNA]
CTD PMID:20385217, PMID:23499868 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b increases expression ISO Dinitrofluorobenzene results in increased expression of TNFRSF10A mRNA CTD PMID:23999411 NCBI chr15:51,433,853...51,464,215 JBrowse link
G Trib1 tribbles pseudokinase 1 increases expression ISO Dinitrofluorobenzene results in increased expression of TRIB1 mRNA CTD PMID:23999411 NCBI chr 7:99,954,492...99,961,026
Ensembl chr 7:99,954,492...99,961,026
JBrowse link
G Trim27 tripartite motif-containing 27 increases expression ISO Dinitrofluorobenzene results in increased expression of TRIM27 mRNA CTD PMID:23999411 NCBI chr17:45,613,863...45,626,212
Ensembl chr17:45,613,864...45,626,212
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Dinitrofluorobenzene results in increased expression of TXNRD1 mRNA CTD PMID:23445166 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 increases expression ISO Dinitrofluorobenzene results in increased expression of XCL1 mRNA CTD PMID:15719370 NCBI chr13:83,199,402...83,202,845
Ensembl chr13:83,199,264...83,202,864
JBrowse link
G Zfp870 zinc finger protein 870 increases expression ISO Dinitrofluorobenzene results in increased expression of ZNF670 mRNA CTD PMID:23999411 NCBI chr 7:15,158,673...15,172,489
Ensembl chr 7:15,159,422...15,163,866
JBrowse link
G Zxdb zinc finger, X-linked, duplicated B increases expression ISO Dinitrofluorobenzene results in increased expression of ZXDB mRNA CTD PMID:23999411 NCBI chr  X:64,092,609...64,097,967 JBrowse link
perfluorobutyric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha increases expression EXP perfluorobutyric acid analog results in increased expression of ACACA mRNA CTD PMID:21878386 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression EXP perfluorobutyric acid results in increased expression of ACOT1 mRNA CTD PMID:19407336 NCBI chr 6:107,485,088...107,493,082
Ensembl chr 6:107,485,249...107,493,798
JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression EXP
ISO
perfluorobutyric acid analog results in increased expression of ACOX1 mRNA; perfluorobutyric acid results in increased expression of ACOX1 mRNA CTD PMID:19359353, PMID:19407336, PMID:21878386 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Actb actin, beta decreases expression ISO perfluorobutyric acid results in decreased expression of ACTB mRNA CTD PMID:23567314 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Angptl4 angiopoietin-like 4 decreases expression ISO perfluorobutyric acid results in decreased expression of ANGPTL4 mRNA CTD PMID:23567314 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Apoa1 apolipoprotein A1 decreases expression EXP perfluorobutyric acid analog results in decreased expression of APOA1 mRNA CTD PMID:21878386 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoa4 apolipoprotein A4 affects expression EXP perfluorobutyric acid affects the expression of APOA4 mRNA CTD PMID:22071372 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Ar androgen receptor multiple interactions ISO perfluorobutyric acid promotes the reaction [Dihydrotestosterone results in increased activity of AR protein] CTD PMID:29601859 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A decreases expression ISO perfluorobutyric acid results in decreased expression of CPT1A mRNA CTD PMID:23567314 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B increases expression ISO perfluorobutyric acid results in increased expression of CPT1B mRNA CTD PMID:23567314 NCBI chr 7:130,395,211...130,404,731
Ensembl chr 7:130,395,194...130,405,347
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression EXP
ISO
perfluorobutyric acid analog results in decreased expression of CYP1A1 mRNA
perfluorobutyric acid results in decreased expression of CYP1A1 mRNA
CTD PMID:21878386, PMID:23567314 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP perfluorobutyric acid analog results in increased expression of CYP2B2 mRNA CTD PMID:21878386 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP perfluorobutyric acid analog results in increased expression of CYP3A23-3A1 mRNA CTD PMID:21878386 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP perfluorobutyric acid analog results in increased expression of CYP4A1 mRNA; perfluorobutyric acid results in increased expression of CYP4A1 mRNA CTD PMID:19407336, PMID:21878386 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression EXP perfluorobutyric acid analog results in increased expression of CYP7A1 mRNA CTD PMID:21878386 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases expression EXP perfluorobutyric acid analog results in decreased expression of DIO1 mRNA CTD PMID:21878386 NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression ISO perfluorobutyric acid results in increased expression of EHHADH mRNA CTD PMID:23567314 NCBI chr11:82,945,104...82,978,364
Ensembl chr11:82,945,104...82,978,364
JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression ISO perfluorobutyric acid results in increased expression of FABP1 mRNA CTD PMID:23567314 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Fasn fatty acid synthase increases expression EXP perfluorobutyric acid analog results in increased expression of FASN mRNA CTD PMID:21878386 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression EXP perfluorobutyric acid results in decreased expression of FDFT1 mRNA CTD PMID:22071372 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression EXP perfluorobutyric acid results in decreased expression of HADHA mRNA CTD PMID:22071372 NCBI chr 6:27,589,840...27,628,921
Ensembl chr 6:27,589,657...27,629,175
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta decreases expression EXP perfluorobutyric acid results in decreased expression of HADHB mRNA CTD PMID:22071372 NCBI chr 6:27,555,408...27,589,539
Ensembl chr 6:27,555,412...27,582,995
JBrowse link
G Hhex hematopoietically expressed homeobox decreases expression EXP perfluorobutyric acid results in decreased expression of HHEX mRNA CTD PMID:22071372 NCBI chr 1:256,101,994...256,107,581
Ensembl chr 1:256,101,903...256,107,649
JBrowse link
G Mal mal, T-cell differentiation protein increases expression EXP perfluorobutyric acid analog results in increased expression of MAL mRNA CTD PMID:21878386 NCBI chr 3:120,209,647...120,233,655
Ensembl chr 3:120,209,647...120,233,655
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression ISO perfluorobutyric acid results in decreased expression of NOS2 mRNA CTD PMID:23567314 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO perfluorobutyric acid results in increased activity of NR1I2 protein CTD PMID:28115241 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Pax8 paired box 8 increases expression EXP perfluorobutyric acid results in increased expression of PAX8 mRNA CTD PMID:22071372 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression EXP perfluorobutyric acid analog results in increased expression of PCNA mRNA CTD PMID:21878386 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO perfluorobutyric acid results in increased expression of PDK4 mRNA CTD PMID:23567314 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Plin2 perilipin 2 increases expression ISO perfluorobutyric acid results in increased expression of PLIN2 mRNA CTD PMID:23567314 NCBI chr 5:104,984,413...105,010,863
Ensembl chr 5:104,984,414...105,010,857
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP perfluorobutyric acid analog results in increased expression of POR mRNA CTD PMID:21878386 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases activity
affects response to substance
ISO perfluorobutyric acid results in increased activity of PPARA protein
PPARA protein affects the susceptibility to perfluorobutyric acid
CTD PMID:19359353, PMID:23391484, PMID:28857218 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases activity ISO perfluorobutyric acid results in increased activity of PPARG protein CTD PMID:24998974 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 multiple interactions ISO perfluorobutyric acid binds to and results in decreased activity of PTPN11 protein CTD PMID:27572461 NCBI chr12:40,895,515...40,955,999
Ensembl chr12:40,895,515...40,955,999
JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO perfluorobutyric acid results in increased expression of SCD1 mRNA CTD PMID:23567314 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Thrsp thyroid hormone responsive increases expression EXP perfluorobutyric acid analog results in increased expression of THRSP mRNA CTD PMID:21878386 NCBI chr 1:162,381,251...162,385,575
Ensembl chr 1:162,381,253...162,385,575
JBrowse link
G Ttr transthyretin multiple interactions ISO perfluorobutyric acid affects the reaction [Thyroxine binds to TTR protein] CTD PMID:27528273 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link
G Txnip thioredoxin interacting protein decreases expression ISO perfluorobutyric acid results in decreased expression of TXNIP mRNA CTD PMID:23567314 NCBI chr 2:198,683,168...198,686,971
Ensembl chr 2:198,683,159...198,686,974
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP perfluorobutyric acid analog results in increased expression of UGT1A1 mRNA CTD PMID:21878386 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19792
    role 19738
      application 19385
        reagent 17189
          chromatographic reagent 115
            1-fluoro-2,4-dinitrobenzene 76
            N,N-dimethylformamide dimethyl acetal 0
            N,O-bis(trimethylsilyl)trifluoroacetamide 0
            N-(tert-butyldimethylsilyl)-N-methyltrifluoroacetamide 0
            N-(trimethylsilyl)diethylamine 0
            N-methyl-N-(trimethylsilyl)trifluoroacetamide 0
            N-trimethylsilylimidazole 0
            chlorotrimethylsilane 0
            heptafluorobutyric anhydride 0
            hexamethyldisilazane 0
            pentafluorobenzoyl chloride 0
            perfluorobutyric acid 39
            tert-butyldimethylsilyl chloride 0
            trimethylphenylammonium hydroxide 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.