Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:electrophilic reagent
go back to main search page
Accession:CHEBI:59739 term browser browse the term
Definition:A reagent that forms a bond to its reaction partner (the nucleophile) by accepting both bonding electrons from that reaction partner.
Synonyms:related_synonym: electrophile;   electrophiles;   electrophilic reagents


show annotations for term's descendants           Sort by:
 
15-deoxy-Delta(12,14)-prostaglandin J2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
increases transport
affects glutathionylation
affects export
ISO [ABCC1 protein results in increased transport of 15-deoxy-delta(12,14)-prostaglandin J2 metabolite] affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; [verlukast binds to and results in decreased activity of ABCC1 protein] inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; ABCC1 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [NFE2L2 protein results in increased expression of GCLC protein]]; ABCC1 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]
ABCC1 protein affects the glutathionylation of 15-deoxy-delta(12,14)-prostaglandin J2
ABCC1 protein affects the export of 15-deoxy-delta(12,14)-prostaglandin J2 analog
CTD PMID:14979731, PMID:21728338 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 affects export ISO ABCC3 protein affects the export of 15-deoxy-delta(12,14)-prostaglandin J2 analog CTD PMID:14979731 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Agt angiotensinogen multiple interactions EXP 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in decreased expression of PPARG protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of SERPINE1 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of SERPINE1 protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of SERPINE1 protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]] CTD PMID:18278065 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 multiple interactions ISO [Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein results in increased metabolism of Prostaglandin D2] which results in increased abundance of Dinoprost]] which results in increased abundance of 15-deoxy-delta(12,14)-prostaglandin J2 CTD PMID:19997560 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of AKT1 protein CTD PMID:16611854 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of BGLAP mRNA CTD PMID:12021203 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of BIRC2 protein CTD PMID:15498850 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of BIRC3 protein CTD PMID:15498850 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases cleavage
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of CASP3 protein
[delta(12)-prostaglandin J(2) co-treated with 9-deoxy-delta-9-prostaglandin D2 co-treated with 15-deoxy-delta(12,14)-prostaglandin J2] results in increased cleavage of CASP3 protein
15-deoxy-delta(12,14)-prostaglandin J2 results in increased cleavage of CASP3 protein
15-deoxy-delta(12,14)-prostaglandin J2 results in increased cleavage of and results in increased activity of CASP3 protein
CTD PMID:11785780, PMID:15498850, PMID:16299251, PMID:23973622 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:15498850 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:15498850 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions ISO CAT protein inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]] CTD PMID:12847270 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Dexamethasone binds to NR3C1 protein] which results in decreased expression of CCL2 protein] CTD PMID:15187150 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA] CTD PMID:23688403 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of and results in increased secretion of CCN2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of CCN2 mRNA]; SMAD2 protein modified form affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of CCN2]] CTD PMID:19429239 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CCNA2 protein CTD PMID:15729575 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CCNB1 protein CTD PMID:15729575 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CCND3 protein CTD PMID:15729575 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CCNE1 protein CTD PMID:15729575 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CDK2 protein CTD PMID:15729575 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
decreases expression
ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of CDKN1A
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CDKN1A protein
CTD PMID:15254749, PMID:15729575 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CDKN1B protein CTD PMID:15729575 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of CEBPA mRNA CTD PMID:12021203 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CFLAR protein CTD PMID:15498850 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CHUK protein]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride results in increased phosphorylation of CHUK protein]
CTD PMID:15498850, PMID:22245093 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of COL1A1 mRNA CTD PMID:12021203 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CSF2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CSF2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of CSF2 mRNA]; Dexamethasone promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CSF2 mRNA]] CTD PMID:12604364, PMID:14998300 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Ddx58 DEXD/H-box helicase 58 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of DDX58 mRNA] CTD PMID:16303604 NCBI chr 5:56,486,584...56,536,898
Ensembl chr 5:56,500,734...56,536,772
JBrowse link
G Egr1 early growth response 1 multiple interactions EXP 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased activity of EGR1 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Oxygen deficiency results in increased expression of EGR1 mRNA] CTD PMID:12468449 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions
increases expression
ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Tretinoin] results in increased expression of FABP4 mRNA
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of FABP4 mRNA
CTD PMID:9543393, PMID:12021203, PMID:16573735 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of FAS mRNA CTD PMID:16712844 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased activity of [FOS protein binds to JUN protein]]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of FOS mRNA]; U 0126 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of FOS mRNA]; wortmannin inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of FOS mRNA]
CTD PMID:11457450, PMID:11687581 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
increases expression
ISO 15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [NFE2L2 protein results in increased expression of GCLC protein]; [ABCC1 protein results in increased transport of 15-deoxy-delta(12,14)-prostaglandin J2 metabolite] affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; [verlukast binds to and results in decreased activity of ABCC1 protein] inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; ABCC1 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [NFE2L2 protein results in increased expression of GCLC protein]]; ABCC1 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; NFE2L2 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC mRNA; 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein
CTD PMID:21728338 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gfap glial fibrillary acidic protein increases expression
decreases expression
multiple interactions
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GFAP
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of GFAP mRNA
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [ochratoxin A results in decreased expression of GFAP mRNA]
CTD PMID:15254749, PMID:15994020 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTA3 mRNA CTD PMID:14652005 NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions ISO GSTM1 protein affects the metabolism of [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Glutathione] CTD PMID:14979731 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression
multiple interactions
EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 mRNA; 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 protein
Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 mRNA]; Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 protein]
CTD PMID:11600134 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hdac1 histone deacetylase 1 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of HDAC1 mRNA CTD PMID:21957481 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac2 histone deacetylase 2 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of HDAC2 mRNA CTD PMID:21957481 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hdac3 histone deacetylase 3 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of HDAC3 mRNA CTD PMID:21957481 NCBI chr18:31,073,057...31,094,347
Ensembl chr18:31,073,058...31,094,303
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha affects stability
multiple interactions
increases expression
ISO 15-deoxy-delta(12,14)-prostaglandin J2 affects the stability of HIF1A protein
Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]; Buthionine Sulfoximine promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]; Dithiothreitol inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]
CTD PMID:17658243 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein; [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron; [[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species; [[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased expression of MMP1 mRNA; [[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein; Acetylcysteine inhibits the reaction [[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein]; HMOX1 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of MMP1 protein]; HSF1 protein inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 mRNA]; NFE2L2 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 mRNA]; zinc protoporphyrin inhibits the reaction [[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron]
ochratoxin A inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 mRNA; 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 protein
CTD PMID:11078701, PMID:15618017, PMID:15994020, PMID:19136476 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsf1 heat shock transcription factor 1 multiple interactions ISO HSF1 protein inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 mRNA] CTD PMID:15618017 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of HSPB1 protein CTD PMID:16299251 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
decreases secretion
ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[IFNG protein results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased activity of and results in increased localization of [STAT1 protein binds to STAT1 protein]]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased expression of IRF1 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased expression of NOS2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased secretion of IFNG protein]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; CAT protein inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]]; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; Hydrogen Peroxide promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; peroxyvanadate inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased abundance of Nitric Oxide]]; peroxyvanadate inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; T 0070907 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased secretion of IFNG protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of IFNG protein
CTD PMID:12847270, PMID:16844232, PMID:19888466 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA] CTD PMID:14998300 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
decreases activity
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein affects the localization of RELA protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in decreased abundance of Prostaglandins]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased abundance of Nitric Oxide]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased activity of [FOS protein binds to JUN protein]]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CSF2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CSF2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [IL1B protein affects the localization of JUN protein]; Dexamethasone promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CSF2 mRNA]]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of IL1B protein
[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with IL1B protein] results in decreased secretion of IL1B protein
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of IL1B protein
CTD PMID:11457450, PMID:12604364, PMID:14998300, PMID:15751073, PMID:16461118 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist decreases expression EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of IL1RN mRNA CTD PMID:15751073 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il4 interleukin 4 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; [Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2] CTD PMID:23688403 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT1 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:12604364, PMID:12847270 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ins2 insulin 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Fatty Acids, Nonesterified inhibits the reaction [INS protein results in increased secretion of Glucose]]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of INS mRNA] CTD PMID:14625208 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased expression of IRF1 mRNA] CTD PMID:12847270 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]]; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]] CTD PMID:12847270 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased activity of [FOS protein binds to JUN protein]]; 15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [IL1B protein affects the localization of JUN protein] CTD PMID:11457450 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Klf6 Kruppel-like factor 6 multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of KLF6 protein; RPS6KB1 protein inhibits the reaction [[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of KLF6 protein] CTD PMID:16611854 NCBI chr17:67,887,939...67,945,052
Ensembl chr17:67,887,939...67,945,037
JBrowse link
G Lep leptin multiple interactions
increases secretion
ISO [Dexamethasone co-treated with 15-deoxy-delta(12,14)-prostaglandin J2] results in decreased secretion of LEP protein
15-deoxy-delta(12,14)-prostaglandin J2 results in increased secretion of LEP protein
CTD PMID:11092516 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lif LIF, interleukin 6 family cytokine multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]]; T 0070907 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]; T 0070907 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]] CTD PMID:19922793 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Lpl lipoprotein lipase increases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of LPL mRNA CTD PMID:12021203 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation
multiple interactions
increases phosphorylation
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased phosphorylation of MAPK1 protein
15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of and results in increased activity of MAPK1 protein; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of and results in increased activity of MAPK1 protein]; U 0126 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of and results in increased activity of MAPK1 protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK1 protein]; [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of MAPK1 protein; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK1 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK1 protein]
CTD PMID:11687581, PMID:12083801, PMID:16611854, PMID:19888466 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation
multiple interactions
increases phosphorylation
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased phosphorylation of MAPK3 protein
15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of and results in increased activity of MAPK3 protein; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of and results in increased activity of MAPK3 protein]; U 0126 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of and results in increased activity of MAPK3 protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK3 protein]; [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of MAPK3 protein; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK3 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK3 protein]
CTD PMID:11687581, PMID:12083801, PMID:16611854, PMID:19888466 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Med1 mediator complex subunit 1 multiple interactions ISO MED1 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of PPARG protein] CTD PMID:16324150 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions
increases expression
ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of MMP1 protein; [[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased expression of MMP1 mRNA; [[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein; Acetylcysteine inhibits the reaction [[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein]; Cycloheximide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]; Dactinomycin inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]; Deferoxamine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 mRNA]; Deferoxamine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]; HMOX1 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of MMP1 protein]; NFE2L2 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 mRNA] CTD PMID:19136476 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of MMP9 protein; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of MMP9 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of MMP9 mRNA] CTD PMID:19997048 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of MTOR protein CTD PMID:16611854 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Nes nestin increases expression EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of NES protein CTD PMID:15212945 NCBI chr 2:187,343,109...187,352,972
Ensembl chr 2:187,344,056...187,352,969
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 affects the localization of and results in increased activity of NFE2L2 protein; 15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [NFE2L2 protein results in increased expression of GCLC protein]; ABCC1 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [NFE2L2 protein results in increased expression of GCLC protein]]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of NFE2L2 protein]; NFE2L2 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; NFE2L2 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 mRNA]; NFE2L2 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and affects the localization of NFE2L2 protein; manganese chloride inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of NFE2L2 protein]
CTD PMID:19136476, PMID:21728338, PMID:22245093 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
decreases localization
ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased localization of NFKB1 protein
CTD PMID:11457450, PMID:16299251 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
decreases phosphorylation
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride results in increased degradation of NFKBIA protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased phosphorylation of NFKBIA protein
CTD PMID:15498850, PMID:22245093, PMID:23688403 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases activity
decreases expression
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of NOS2 protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [ochratoxin A results in increased expression of NOS2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of NOS2 protein
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of NOS2 mRNA
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[IFNG protein results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased expression of NOS2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of NOS2 protein; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of NOS2 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of NOS2 mRNA]
CTD PMID:11457450, PMID:11890746, PMID:12847270, PMID:15684285, PMID:15994020, PMID:16461118, PMID:19997048 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 decreases activity EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of NOS3 protein CTD PMID:11890746 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects activity
multiple interactions
ISO 15-deoxy-delta(12,14)-prostaglandin J2 affects the activity of NR3C1 protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Dexamethasone binds to NR3C1 protein] which results in decreased expression of CCL2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Dexamethasone binds to NR3C1 protein]
CTD PMID:15187150 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions EXP 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride results in decreased expression of PARK7 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride results in decreased expression of PARK7 protein] CTD PMID:22245093 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 results in increased cleavage of PARP1 protein
[delta(12)-prostaglandin J(2) co-treated with 9-deoxy-delta-9-prostaglandin D2 co-treated with 15-deoxy-delta(12,14)-prostaglandin J2] results in increased cleavage of PARP1 protein
CTD PMID:15498850, PMID:23973622 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 increases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of PCK1 mRNA CTD PMID:9518257 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased activity of PPARA protein CTD PMID:9013583 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of PPARD protein CTD PMID:17341418 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects expression
decreases response to substance
increases expression
increases activity
multiple interactions
decreases expression
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 affects the expression of PPARG
PPARG protein mutant form results in decreased susceptibility to 15-deoxy-delta(12,14)-prostaglandin J2
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of PPARG mRNA; 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of PPARG protein
15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of PPARG protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in decreased expression of PPARG protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [ochratoxin A results in increased expression of PPARG mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased activity of PPARG protein; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [PPARG protein affects the reaction [Lipopolysaccharides results in increased abundance of Nitric Oxide]]; MED1 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of PPARG protein]
15-deoxy-delta(12,14)-prostaglandin J2 affects the localization of and results in increased expression of PPARG protein; 15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in decreased activity of PPARG protein; 15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased activity of PPARG protein; 15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased localization of and results in increased activity of PPARG protein; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [deoxynivalenol results in increased expression of PPARG protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of PPARG mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in decreased expression of PPARG mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of PPARG protein]; MG 262 promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of PPARG protein]; PPARG protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of TBXA2R mRNA alternative form]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of PPARG protein
CTD PMID:9013583, PMID:10662598, PMID:11030710, PMID:12065695, PMID:12604364, PMID:12839938, PMID:12847270, PMID:14625208, PMID:14979731, PMID:14998300, PMID:15212945, PMID:15254749, PMID:15322177, PMID:15491415, PMID:15707588, PMID:15729575, PMID:15866424, PMID:15994020, PMID:16324150, PMID:16499875, PMID:17341418, PMID:18278065, PMID:18485432, PMID:19922793, PMID:23943857, PMID:26172262, PMID:30138673 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in increased expression of PTEN protein CTD PMID:16611854 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptgdr prostaglandin D2 receptor multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased activity of PTGDR protein; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Prostaglandin D2 binds to PTGDR protein] CTD PMID:9579725 NCBI chr15:19,195,606...19,196,508 JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased activity of PTGDR2 protein; ramatroban inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased activity of PTGDR2 protein]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Prostaglandin D2 binds to PTGDR2 protein]
CTD PMID:12721327, PMID:16256979 NCBI chr 1:226,976,455...226,995,641
Ensembl chr 1:226,993,250...226,994,849
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO PTGS1 protein promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased abundance of 15-deoxy-delta(12,14)-prostaglandin J2] CTD PMID:17439952 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression
increases expression
ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of PTGS2 protein; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of PTGS2 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of PTGS2 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of PTGS2
CTD PMID:11457450, PMID:12604364, PMID:15254749, PMID:19997048 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 increases phosphorylation EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of PTPN11 protein CTD PMID:12584205 NCBI chr12:40,895,515...40,955,999
Ensembl chr12:40,895,515...40,955,999
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of and results in decreased phosphorylation of RAF1 protein CTD PMID:12083801 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Rarb retinoic acid receptor, beta multiple interactions
increases expression
ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [ciglitazone promotes the reaction [SR 11237 results in increased expression of RARB protein]]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of RARB
CTD PMID:12839938, PMID:15254749 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased phosphorylation of and results in decreased expression of RB1 protein CTD PMID:15729575 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases activity
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein affects the localization of RELA protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of RELA protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride affects the localization of RELA protein]
CTD PMID:11457450, PMID:15498850, PMID:20174873, PMID:22245093 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of RPS6KA1 protein CTD PMID:16611854 NCBI chr 5:152,078,217...152,122,684
Ensembl chr 5:152,078,220...152,122,684
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of and results in decreased activity of RPS6KB1 protein; RPS6KB1 protein inhibits the reaction [[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased expression of TGFB1 mRNA]; RPS6KB1 protein inhibits the reaction [[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of KLF6 protein] CTD PMID:16611854 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Runx2 RUNX family transcription factor 2 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of RUNX2 mRNA CTD PMID:12021203 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Rxra retinoid X receptor alpha increases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of RXRA CTD PMID:15254749 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions EXP 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of SERPINE1 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of SERPINE1 protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of SERPINE1 protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]] CTD PMID:18278065 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Smad2 SMAD family member 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein]; SMAD2 protein modified form affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of CCN2]] CTD PMID:19429239 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Socs1 suppressor of cytokine signaling 1 increases expression EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of SOCS1 mRNA CTD PMID:12584205 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461
JBrowse link
G Socs3 suppressor of cytokine signaling 3 increases expression EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of SOCS3 mRNA CTD PMID:12584205 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of SPP1 mRNA CTD PMID:12021203 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT1 protein]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT1 protein]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased activity of and results in increased localization of [STAT1 protein binds to STAT1 protein]]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [peroxyvanadate results in increased phosphorylation of STAT1 protein]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; CAT protein inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; Hydrogen Peroxide promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; peroxyvanadate inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]
CTD PMID:12584205, PMID:12847270 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]]; T 0070907 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]; T 0070907 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]
CTD PMID:12584205, PMID:12847270, PMID:19922793 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tbxa2r thromboxane A2 receptor multiple interactions
decreases expression
ISO PPARG protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of TBXA2R mRNA alternative form] CTD PMID:16499875 NCBI chr 7:11,253,153...11,259,233
Ensembl chr 7:11,253,180...11,257,977
JBrowse link
G Tg thyroglobulin multiple interactions
increases expression
ISO 15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [TSHB protein results in increased expression of TG protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of TG protein
CTD PMID:11078701 NCBI chr 7:107,467,260...107,652,897
Ensembl chr 7:107,467,260...107,652,899
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases expression
decreases response to substance
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of and results in increased secretion of CCN2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of CCN2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein]; SMAD2 protein modified form affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of CCN2]]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of TGFB1 mRNA
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]
15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [alitretinoin results in decreased expression of TGFB1 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [[alitretinoin co-treated with 15-deoxy-delta(12,14)-prostaglandin J2] results in decreased expression of TGFB1 mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [[alitretinoin co-treated with 15-deoxy-delta(12,14)-prostaglandin J2] results in decreased expression of TGFB1 mRNA]; RPS6KB1 protein inhibits the reaction [[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased expression of TGFB1 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased susceptibility to TGFB1 protein
CTD PMID:16611854, PMID:18278065, PMID:19429239 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Th tyrosine hydroxylase increases expression EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of TH protein CTD PMID:15212945 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions
decreases expression
ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of TLR2 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of TLR2 mRNA
CTD PMID:20174873 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions
ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of TNF protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
CTD PMID:12604364, PMID:19888466 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [TSHB protein results in increased expression of TG protein] CTD PMID:11078701 NCBI chr 2:205,207,799...205,215,199
Ensembl chr 2:205,207,799...205,212,681
JBrowse link
G Tslp thymic stromal lymphopoietin multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein] CTD PMID:23688403 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361
JBrowse link
G Vim vimentin decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of VIM CTD PMID:15254749 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Wnt10b Wnt family member 10B decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of WNT10B mRNA CTD PMID:12021203 NCBI chr 7:140,448,284...140,466,159
Ensembl chr 7:140,448,465...140,454,268
JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of XIAP protein CTD PMID:15498850, PMID:16299251 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link
ozone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A1bg alpha-1-B glycoprotein increases expression EXP Ozone results in increased expression of A1BG mRNA CTD PMID:25838073 NCBI chr 7:102,294,805...102,298,522
Ensembl chr 7:102,294,797...102,298,522
JBrowse link
G Aass aminoadipate-semialdehyde synthase increases expression EXP Ozone results in increased expression of AASS mRNA CTD PMID:25838073 NCBI chr 4:50,152,005...50,208,935
Ensembl chr 4:50,152,452...50,200,328
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression
multiple interactions
ISO Ozone results in decreased expression of ABCA1 mRNA
Ozone results in decreased expression of ABCA1 mRNA; Ozone results in decreased expression of ABCA1 protein
Ozone inhibits the reaction [TO-901317 results in increased expression of ABCA1 mRNA]
CTD PMID:16183385, PMID:27703007 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
decreases expression
EXP
ISO
Ozone results in increased expression of ABCB1 mRNA
Ozone results in decreased expression of ABCB1A mRNA
CTD PMID:16330353, PMID:31626304 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B multiple interactions
increases expression
EXP [Ozone co-treated with Chlorine] results in decreased expression of ABCB1B mRNA
Ozone results in increased expression of ABCB1B mRNA
CTD PMID:18636392, PMID:26667333 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
increases expression
EXP [Ozone co-treated with Chlorine] results in decreased expression of ABCC1 mRNA
Ozone results in increased expression of ABCC1 mRNA
CTD PMID:16330353, PMID:18636392 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 multiple interactions ISO Ozone inhibits the reaction [TO-901317 results in increased expression of ABCG1 mRNA] CTD PMID:27703007 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 decreases expression ISO Ozone results in decreased expression of ABCG2 mRNA CTD PMID:16183385 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of ACADM mRNA CTD PMID:18636392 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589
JBrowse link
G Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 decreases expression EXP Ozone results in decreased expression of ACAP1 mRNA CTD PMID:28623178 NCBI chr10:56,492,300...56,506,446
Ensembl chr10:56,492,300...56,506,446
JBrowse link
G Acer2 alkaline ceramidase 2 decreases expression ISO Ozone results in decreased expression of ACER2 mRNA CTD PMID:19555225 NCBI chr 5:105,230,540...105,279,732
Ensembl chr 5:105,230,580...105,279,731
JBrowse link
G Acly ATP citrate lyase decreases expression ISO
EXP
Ozone results in decreased expression of ACLY mRNA CTD PMID:16183385, PMID:25838073 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Aco2 aconitase 2 increases expression EXP Ozone results in increased expression of ACO2 mRNA CTD PMID:25838073 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression EXP Ozone results in increased expression of ACOT1 mRNA CTD PMID:25838073 NCBI chr 6:107,485,088...107,493,082
Ensembl chr 6:107,485,249...107,493,798
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression EXP Ozone results in increased expression of ACOT2 mRNA CTD PMID:25838073 NCBI chr 6:107,460,596...107,468,324
Ensembl chr 6:107,460,668...107,467,487
JBrowse link
G Acot7 acyl-CoA thioesterase 7 multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of ACOT7 mRNA CTD PMID:18636392 NCBI chr 5:169,357,582...169,450,215
Ensembl chr 5:169,357,517...169,450,219
JBrowse link
G Acot9 acyl-CoA thioesterase 9 increases expression ISO Ozone results in increased expression of ACOT9 mRNA CTD PMID:17095637 NCBI chr  X:43,543,069...43,592,200
Ensembl chr  X:43,543,070...43,592,200
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression
multiple interactions
ISO
EXP
Ozone results in decreased expression of ACSL1 mRNA
[Ozone co-treated with Chlorine] affects the expression of ACSL1 mRNA
CTD PMID:12763052, PMID:18636392 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle decreases expression ISO Ozone results in decreased expression of ACTA1 mRNA CTD PMID:12763052 NCBI chr19:56,674,072...56,677,084
Ensembl chr19:56,674,074...56,677,084
JBrowse link
G Actb actin, beta decreases expression EXP Ozone results in decreased expression of ACTB mRNA CTD PMID:16330353 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 decreases expression ISO Ozone results in decreased expression of ACTC1 mRNA CTD PMID:12763052 NCBI chr 3:105,507,403...105,512,939
Ensembl chr 3:105,507,403...105,512,939
JBrowse link
G Acvr1 activin A receptor type 1 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of ACVR1 mRNA CTD PMID:18636392 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 increases expression
decreases expression
EXP Ozone results in increased expression of ADAMTS1 mRNA
Ozone results in decreased expression of ADAMTS1 mRNA
CTD PMID:16716893, PMID:31397875 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 multiple interactions
increases expression
ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of ADAMTS4 mRNA
Ozone results in increased expression of ADAMTS4 mRNA
CTD PMID:17460151, PMID:19555225, PMID:25658374 NCBI chr13:89,622,996...89,632,485
Ensembl chr13:89,622,632...89,634,419
JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 increases expression EXP Ozone results in increased expression of ADAMTS9 mRNA CTD PMID:28623178 NCBI chr 4:124,660,254...124,860,997
Ensembl chr 4:124,660,262...124,858,250
JBrowse link
G Adcy2 adenylate cyclase 2 multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of ADCY2 mRNA CTD PMID:18636392 NCBI chr 1:37,043,071...37,698,390
Ensembl chr 1:37,507,276...37,698,390
JBrowse link
G Adcy3 adenylate cyclase 3 multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of ADCY3 mRNA CTD PMID:18636392 NCBI chr 6:28,570,941...28,648,848
Ensembl chr 6:28,571,351...28,650,148
JBrowse link
G Adcy4 adenylate cyclase 4 decreases expression
multiple interactions
ISO
EXP
Ozone results in decreased expression of ADCY4 mRNA
[Ozone co-treated with Chlorine] affects the expression of ADCY4 mRNA
CTD PMID:12763052, PMID:18636392 NCBI chr15:34,453,917...34,469,779
Ensembl chr15:34,453,915...34,469,746
JBrowse link
G Adcy5 adenylate cyclase 5 multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of ADCY5 mRNA CTD PMID:18636392 NCBI chr11:68,695,839...68,842,452
Ensembl chr11:68,695,839...68,842,320
JBrowse link
G Adcy8 adenylate cyclase 8 multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of ADCY8 mRNA CTD PMID:18636392 NCBI chr 7:105,353,883...105,593,372
Ensembl chr 7:105,353,913...105,592,804
JBrowse link
G Adgre5 adhesion G protein-coupled receptor E5 decreases expression EXP Ozone results in decreased expression of ADGRE5 mRNA CTD PMID:28623178 NCBI chr19:24,854,981...24,875,712
Ensembl chr19:24,855,299...24,875,137
JBrowse link
G Adgrg2 adhesion G protein-coupled receptor G2 increases expression EXP Ozone results in increased expression of ADGRG2 mRNA CTD PMID:28623178 NCBI chr  X:36,930,186...37,054,968
Ensembl chr  X:36,930,186...37,003,642
JBrowse link
G Adgrl1 adhesion G protein-coupled receptor L1 multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of ADGRL1 mRNA CTD PMID:18636392 NCBI chr19:25,029,037...25,069,146
Ensembl chr19:25,029,037...25,069,142
JBrowse link
G Adgrl3 adhesion G protein-coupled receptor L3 decreases expression ISO Ozone results in decreased expression of ADGRL3 mRNA CTD PMID:31626304 NCBI chr14:28,362,176...29,226,085
Ensembl chr14:28,393,394...28,967,980
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression
increases expression
affects response to substance
multiple interactions
ISO
EXP
Ozone results in decreased expression of ADIPOQ mRNA
Ozone results in increased expression of ADIPOQ
ADIPOQ protein affects the susceptibility to Ozone
[ADIPOQ protein binds to CDH13 protein] inhibits the reaction [Ozone results in increased expression of IL17A mRNA]; ADIPOQ gene mutant form promotes the reaction [Ozone results in increased expression of IL17A mRNA]; ADIPOQ gene mutant form promotes the reaction [Ozone results in increased expression of SAA3 mRNA]
CTD PMID:12763052, PMID:23755285, PMID:24103449 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adm adrenomedullin increases expression EXP
ISO
Ozone results in increased expression of ADM mRNA CTD PMID:16716893, PMID:27206323 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Adora1 adenosine A1 receptor increases expression EXP Ozone results in increased expression of ADORA1 mRNA CTD PMID:28623178 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adora2a adenosine A2a receptor increases expression
multiple interactions
ISO Ozone results in increased expression of ADORA2A mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of ADORA2A mRNA
CTD PMID:31476115 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Adora3 adenosine A3 receptor multiple interactions
decreases expression
EXP
ISO
[Ozone co-treated with Chlorine] results in increased expression of ADORA3 mRNA
Ozone results in decreased expression of ADORA3 mRNA
CTD PMID:18636392, PMID:31626304 NCBI chr 2:208,336,909...208,379,217
Ensembl chr 2:208,373,154...208,376,803
JBrowse link
G Adra2c adrenoceptor alpha 2C multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of ADRA2C mRNA CTD PMID:18636392 NCBI chr14:80,730,307...80,732,010
Ensembl chr14:80,730,307...80,732,010
JBrowse link
G Adrb2 adrenoceptor beta 2 affects response to substance
multiple interactions
ISO
EXP
ADRB2 protein affects the susceptibility to Ozone
[Ozone co-treated with Chlorine] affects the expression of ADRB2 mRNA
CTD PMID:10926562, PMID:18636392 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Adrb3 adrenoceptor beta 3 decreases expression ISO Ozone results in decreased expression of ADRB3 mRNA CTD PMID:12763052, PMID:17460151 NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632
JBrowse link
G Aen apoptosis enhancing nuclease increases expression ISO Ozone results in increased expression of AEN mRNA CTD PMID:28652203 NCBI chr 1:140,584,328...140,593,749
Ensembl chr 1:140,584,380...140,593,745
JBrowse link
G Afp alpha-fetoprotein multiple interactions ISO TTPA protein affects the reaction [Ozone results in increased expression of AFP mRNA] CTD PMID:19555225 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of AGER mRNA; [Ozone co-treated with Vehicle Emissions] results in increased expression of AGER mRNA CTD PMID:18636392, PMID:20980218 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression ISO
EXP
Ozone results in increased expression of AGTR1 protein
Ozone results in increased expression of AGTR1 mRNA
CTD PMID:26667334, PMID:27679563 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Ahdc1 AT hook, DNA binding motif, containing 1 decreases expression ISO Ozone results in decreased expression of AHDC1 mRNA CTD PMID:31626304 NCBI chr 5:151,209,894...151,277,192
Ensembl chr 5:151,211,342...151,277,165
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases expression
decreases expression
affects localization
ISO AHR protein affects the reaction [Ozone results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [Ozone results in increased expression of CYP1A1 protein]; AHR protein affects the reaction [Ozone results in increased expression of CYP1A2 mRNA]; AHR protein affects the reaction [Ozone results in increased expression of CYP1A2 protein]; AHR protein affects the reaction [Ozone results in increased expression of CYP1B1 mRNA]; AHR protein affects the reaction [Ozone results in increased expression of CYP1B1 protein]; AHR protein affects the reaction [Ozone results in increased phosphorylation of EGFR protein]
Ozone results in increased expression of AHR mRNA
Ozone results in decreased expression of AHR mRNA
Ozone affects the localization of AHR protein
CTD PMID:12763052, PMID:19536146 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of AKR1A1 mRNA CTD PMID:18636392 NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 multiple interactions
increases expression
ISO
EXP
TTPA protein affects the reaction [Ozone results in increased expression of AKR1B8 mRNA] CTD PMID:16716893, PMID:19555225 NCBI chr 4:61,772,064...61,784,637
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
increases expression
multiple interactions
ISO
EXP
Ozone results in increased phosphorylation of AKT1 protein
Ozone results in increased expression of AKT1 protein
[Ozone co-treated with Chlorine] results in increased expression of AKT1 mRNA
CTD PMID:18636392, PMID:19536146, PMID:26949510 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of AKT2 mRNA CTD PMID:18636392 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 decreases expression ISO Ozone results in decreased expression of ALAS2 mRNA CTD PMID:12763052 NCBI chr  X:23,167,576...23,187,356
Ensembl chr  X:23,167,696...23,187,341
JBrowse link
G Alb albumin increases expression
multiple interactions
ISO
EXP
Ozone results in increased expression of ALB protein
ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of ALB protein]
Ozone results in increased expression of ALB mRNA
Ozone results in increased expression of ALB mRNA; Ozone results in increased expression of ALB protein
[Ozone co-treated with Particulate Matter] results in increased expression of ALB protein; IL10 protein inhibits the reaction [Ozone results in increased expression of ALB protein]
CTD PMID:10593593, PMID:10706030, PMID:12377989, PMID:14515223, PMID:24136897, PMID:24862973, PMID:25838073, PMID:26667333, PMID:27206323, PMID:29947284 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of ALDH1A3 mRNA CTD PMID:25658374 NCBI chr 1:127,302,920...127,337,828
Ensembl chr 1:127,301,128...127,337,882
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression EXP Ozone results in increased expression of ALDOA mRNA CTD PMID:25838073 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of ALDOC mRNA CTD PMID:18636392 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Alkbh1 alkB homolog 1, histone H2A dioxygenase decreases expression EXP Ozone results in decreased expression of NRP mRNA CTD PMID:26667333 NCBI chr 6:111,456,096...111,476,829
Ensembl chr 6:111,456,187...111,477,090
JBrowse link
G Alox15 arachidonate 15-lipoxygenase decreases expression ISO Ozone results in decreased expression of ALOX15 mRNA CTD PMID:29471542 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161
JBrowse link
G Amacr alpha-methylacyl-CoA racemase multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of AMACR mRNA CTD PMID:18636392 NCBI chr 2:60,949,276...60,961,342
Ensembl chr 2:60,949,256...60,961,326
JBrowse link
G Amer2 APC membrane recruitment protein 2 decreases expression EXP Ozone results in decreased expression of AMER2 mRNA CTD PMID:31397875 NCBI chr15:40,663,183...40,667,705
Ensembl chr15:40,665,041...40,667,173
JBrowse link
G Ampd1 adenosine monophosphate deaminase 1 decreases expression ISO Ozone results in decreased expression of AMPD1 mRNA CTD PMID:31626304 NCBI chr 2:205,568,934...205,589,961
Ensembl chr 2:205,568,935...205,590,021
JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 multiple interactions ISO pyrazolanthrone inhibits the reaction [Ozone results in increased expression of AMPD3 mRNA] CTD PMID:17460151 NCBI chr 1:175,585,301...175,630,479
Ensembl chr 1:175,586,097...175,630,467
JBrowse link
G Amph amphiphysin multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of AMPH mRNA CTD PMID:18636392 NCBI chr17:48,304,324...48,562,838
Ensembl chr17:48,304,322...48,562,905
JBrowse link
G Ang2 angiogenin, ribonuclease A family, member 2 decreases expression ISO Ozone results in decreased expression of ANG2 mRNA CTD PMID:12763052 NCBI chr15:28,103,688...28,121,494
Ensembl chr15:28,103,703...28,104,206
JBrowse link
G Angpt1 angiopoietin 1 decreases expression
increases expression
ISO Ozone results in decreased expression of ANGPT1 mRNA
Ozone results in increased expression of ANGPT1 mRNA
CTD PMID:17460151, PMID:21543283 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
G Angptl2 angiopoietin-like 2 increases expression ISO Ozone results in increased expression of ANGPTL2 mRNA CTD PMID:31626304 NCBI chr 3:12,262,822...12,292,665
Ensembl chr 3:12,262,822...12,292,663
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO Ozone results in increased expression of ANGPTL4 mRNA CTD PMID:17095637, PMID:28652203 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Ankle1 ankyrin repeat and LEM domain containing 1 decreases expression ISO Ozone results in decreased expression of ANKLE1 mRNA CTD PMID:24336422 NCBI chr16:19,799,943...19,826,057
Ensembl chr16:19,800,463...19,803,796
JBrowse link
G Ankrd2 ankyrin repeat domain 2 increases expression ISO Ozone results in increased expression of ANKRD2 mRNA CTD PMID:31626304 NCBI chr 1:261,281,859...261,291,307
Ensembl chr 1:261,281,543...261,291,394
JBrowse link
G Anks1b ankyrin repeat and sterile alpha motif domain containing 1B decreases expression ISO Ozone results in decreased expression of ANKS1B mRNA CTD PMID:31626304 NCBI chr 7:30,507,135...31,684,604
Ensembl chr 7:30,699,476...31,681,182
JBrowse link
G Anln anillin, actin binding protein multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of ANLN mRNA; TTPA protein affects the reaction [Ozone results in increased expression of ANLN mRNA] CTD PMID:19555225, PMID:25658374 NCBI chr 8:23,336,455...23,397,122
Ensembl chr 8:23,337,621...23,390,773
JBrowse link
G Ano6 anoctamin 6 multiple interactions
increases expression
ISO alpha-Tocopherol inhibits the reaction [Ozone results in increased expression of ANO6 mRNA] CTD PMID:27886375 NCBI chr 7:137,142,063...137,335,208
Ensembl chr 7:137,142,170...137,335,208
JBrowse link
G Anxa1 annexin A1 increases expression ISO Ozone results in increased expression of ANXA1 mRNA CTD PMID:12763052 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Anxa2 annexin A2 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of ANXA2 mRNA CTD PMID:18636392 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Anxa3 annexin A3 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of ANXA3 mRNA CTD PMID:18636392 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
JBrowse link
G Anxa4 annexin A4 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of ANXA4 mRNA CTD PMID:18636392 NCBI chr 4:118,538,775...118,595,591
Ensembl chr 4:118,538,777...118,595,580
JBrowse link
G Anxa5 annexin A5 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of ANXA5 mRNA CTD PMID:18636392 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Aox1 aldehyde oxidase 1 decreases expression ISO Ozone results in decreased expression of AOX1 mRNA CTD PMID:12763052 NCBI chr 9:64,929,682...65,007,872
Ensembl chr 9:64,929,721...65,007,870
JBrowse link
G Ap3m2 adaptor related protein complex 3 subunit mu 2 decreases expression EXP Ozone results in decreased expression of AP3M2 mRNA CTD PMID:28623178 NCBI chr16:74,075,842...74,091,230
Ensembl chr16:74,076,812...74,091,139
JBrowse link
G Apc APC regulator of WNT signaling pathway multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of APC mRNA CTD PMID:18636392 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 multiple interactions
increases expression
EXP [Ozone co-treated with Chlorine] results in decreased expression of APEX1 mRNA
Ozone results in increased expression of APEX1 mRNA
CTD PMID:16330353, PMID:18636392 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Apln apelin increases methylation
decreases expression
EXP Ozone results in increased methylation of APLN promoter
Ozone results in decreased expression of APLN mRNA
CTD PMID:29947284 NCBI chr  X:134,856,719...134,866,210
Ensembl chr  X:134,856,726...134,866,210
JBrowse link
G Apod apolipoprotein D multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of APOD mRNA CTD PMID:18636392 NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301
JBrowse link
G Apoe apolipoprotein E decreases expression ISO Ozone results in decreased expression of APOE mRNA CTD PMID:12763052 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Apold1 apolipoprotein L domain containing 1 increases expression EXP Ozone results in increased expression of APOLD1 mRNA CTD PMID:28623178 NCBI chr 4:168,752,142...168,755,024
Ensembl chr 4:168,752,133...168,755,023
JBrowse link
G App amyloid beta precursor protein multiple interactions
increases expression
increases response to substance
ISO [Ozone co-treated with Particulate Matter] results in increased expression of APP protein
Ozone results in increased expression of APP protein
APP results in increased susceptibility to Ozone
CTD PMID:15513908, PMID:26116027, PMID:29385576 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Aqp1 aquaporin 1 multiple interactions
decreases expression
EXP
ISO
[Ozone co-treated with Chlorine] results in decreased expression of AQP1 mRNA
Ozone results in decreased expression of AQP1 mRNA
CTD PMID:18636392, PMID:27206323 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) multiple interactions
increases expression
EXP [Ozone co-treated with Chlorine] affects the expression of AQP3 mRNA
Ozone results in increased expression of AQP3 mRNA
CTD PMID:18636392, PMID:26667333 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Aqp4 aquaporin 4 increases expression ISO Ozone results in increased expression of AQP4 mRNA CTD PMID:27206323 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Aqp9 aquaporin 9 decreases expression EXP Ozone results in decreased expression of AQP9 mRNA CTD PMID:26667333 NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781
JBrowse link
G Areg amphiregulin increases expression
multiple interactions
ISO
EXP
Ozone results in increased expression of AREG mRNA
[NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of AREG mRNA; TTPA protein affects the reaction [Ozone results in increased expression of AREG mRNA]
CTD PMID:16716893, PMID:17095637, PMID:19555225, PMID:25658374 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arf1 ADP-ribosylation factor 1 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of ARF1 mRNA CTD PMID:18636392 NCBI chr10:45,562,700...45,579,214
Ensembl chr10:45,563,547...45,579,029
JBrowse link
G Arf3 ADP-ribosylation factor 3 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of ARF3 mRNA CTD PMID:18636392 NCBI chr 7:140,412,463...140,438,751
Ensembl chr 7:140,398,199...140,437,467
JBrowse link
G Arf4 ADP-ribosylation factor 4 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of ARF4 mRNA CTD PMID:18636392 NCBI chr16:2,338,333...2,354,909
Ensembl chr16:2,338,333...2,354,909
JBrowse link
G Arf5 ADP-ribosylation factor 5 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of ARF5 mRNA CTD PMID:18636392 NCBI chr 4:55,715,744...55,718,670
Ensembl chr 4:55,715,744...55,718,670
JBrowse link
G Arf6 ADP-ribosylation factor 6 multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of ARF6 mRNA CTD PMID:18636392 NCBI chr 6:91,697,109...91,698,257
Ensembl chr 6:91,697,109...91,698,255
JBrowse link
G Arg1 arginase 1 multiple interactions
increases expression
EXP [Ozone co-treated with Chlorine] affects the expression of ARG1 mRNA
Ozone results in increased expression of ARG1 mRNA; Ozone results in increased expression of ARG1 protein
CTD PMID:18636392, PMID:22727909, PMID:25838073 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Arg2 arginase 2 multiple interactions
increases expression
ISO TTPA protein affects the reaction [Ozone results in increased expression of ARG2 mRNA] CTD PMID:17095637, PMID:19555225 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Arhgap11a Rho GTPase activating protein 11A multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of ARHGAP11A mRNA CTD PMID:25658374 NCBI chr 3:105,281,827...105,298,108
Ensembl chr 3:105,281,827...105,298,108
JBrowse link
G Arhgap35 Rho GTPase activating protein 35 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of ARHGAP35 mRNA CTD PMID:18636392 NCBI chr 1:78,456,409...78,573,374
Ensembl chr 1:78,456,409...78,573,374
JBrowse link
G Arhgap4 Rho GTPase activating protein 4 decreases expression EXP Ozone results in decreased expression of ARHGAP4 mRNA CTD PMID:28623178 NCBI chr  X:156,873,094...156,888,762
Ensembl chr  X:156,873,849...156,888,761
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression ISO Ozone results in increased expression of ARNT mRNA CTD PMID:27206323 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Arrb1 arrestin, beta 1 increases expression EXP Ozone results in increased expression of ARRB1 mRNA CTD PMID:16330353 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139
JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions
increases expression
EXP [Ozone co-treated with Chlorine] affects the expression of ARRB2 mRNA
Ozone results in increased expression of ARRB2 mRNA
CTD PMID:16330353, PMID:18636392 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Asb3 ankyrin repeat and SOCS box-containing 3 increases expression ISO Ozone results in increased expression of ASB3 mRNA CTD PMID:28652203 NCBI chr14:115,352,716...115,446,618
Ensembl chr14:115,391,609...115,446,152
JBrowse link
G Asf1b anti-silencing function 1B histone chaperone multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of ASF1B mRNA; TTPA protein affects the reaction [Ozone results in increased expression of ASF1B mRNA] CTD PMID:19555225, PMID:25658374 NCBI chr19:25,077,918...25,092,491
Ensembl chr19:25,077,918...25,092,491
JBrowse link
G Asl argininosuccinate lyase increases expression EXP Ozone results in increased expression of ASL mRNA CTD PMID:25838073 NCBI chr12:30,160,922...30,178,348
Ensembl chr12:30,165,694...30,178,341
JBrowse link
G Aspa aspartoacylase increases expression EXP Ozone results in increased expression of ASPA mRNA CTD PMID:28623178, PMID:31397875 NCBI chr10:59,839,693...59,888,244
Ensembl chr10:59,839,852...59,892,960
JBrowse link
G Aspm assembly factor for spindle microtubules multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of ASPM mRNA CTD PMID:25658374 NCBI chr13:56,546,021...56,591,793
Ensembl chr13:56,546,021...56,591,793
JBrowse link
G Ass1 argininosuccinate synthase 1 increases expression EXP Ozone results in increased expression of ASS1 mRNA CTD PMID:25838073 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of ATF2 mRNA CTD PMID:18636392 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO
EXP
Ozone results in increased expression of ATF3 mRNA CTD PMID:16716893, PMID:19555225 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf6b activating transcription factor 6 beta decreases expression
increases expression
ISO Ozone results in decreased expression of ATF6B mRNA
Ozone results in increased expression of ATF6B mRNA
CTD PMID:12763052, PMID:27206323 NCBI chr20:4,414,283...4,422,283
Ensembl chr20:4,414,276...4,422,283
JBrowse link
G Atg7 autophagy related 7 increases expression ISO Ozone results in increased expression of ATG7 mRNA CTD PMID:27206323 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
G Atm ATM serine/threonine kinase increases expression ISO Ozone results in increased expression of ATM mRNA CTD PMID:27206323 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp10b ATPase phospholipid transporting 10B (putative) decreases expression EXP Ozone results in decreased expression of ATP10B mRNA CTD PMID:28623178, PMID:31397875 NCBI chr10:28,449,248...28,862,423
Ensembl chr10:28,449,335...28,864,255
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions
decreases expression
EXP [Ozone co-treated with Chlorine] results in decreased expression of ATP1A1 mRNA
Ozone results in decreased expression of ATP1A1 mRNA
CTD PMID:16330353, PMID:18636392 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 multiple interactions ISO TTPA protein affects the reaction [Ozone results in decreased expression of ATP1A3 mRNA] CTD PMID:19555225 NCBI chr 1:81,852,423...81,881,565
Ensembl chr 1:81,852,429...81,881,549
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 affects response to substance ISO ATP2A2 protein affects the susceptibility to Ozone CTD PMID:19201925 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 decreases expression
multiple interactions
ISO
EXP
Ozone results in decreased expression of ATP2A3 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of ATP2A3 mRNA
CTD PMID:12763052, PMID:18636392 NCBI chr10:59,528,849...59,560,440
Ensembl chr10:59,529,785...59,560,433
JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 decreases expression EXP Ozone results in decreased expression of ATP2B2 mRNA CTD PMID:16330353 NCBI chr 4:145,704,779...145,948,997
Ensembl chr 4:145,703,046...146,016,325
JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of ATP6V0C mRNA CTD PMID:18636392 NCBI chr10:13,537,031...13,543,407
Ensembl chr10:13,537,033...13,542,077
JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 multiple interactions ISO [NOTCH4 gene mutant form affects the susceptibility to Ozone] which affects the expression of ATP6V0D2 mRNA CTD PMID:25658374 NCBI chr 5:33,843,591...33,892,446
Ensembl chr 5:33,843,519...33,892,462
JBrowse link
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 decreases expression ISO Ozone results in decreased expression of ATP6V1B1 mRNA CTD PMID:31626304 NCBI chr 4:115,417,100...115,435,754
Ensembl chr 4:115,416,580...115,437,206
JBrowse link
G Atp7b ATPase copper transporting beta multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of ATP7B mRNA CTD PMID:18636392 NCBI chr16:74,865,516...74,944,935
Ensembl chr16:74,865,516...74,945,286
JBrowse link
G Aurka aurora kinase A multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of AURKA mRNA CTD PMID:25658374 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
JBrowse link
G Aurkb aurora kinase B multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of AURKB mRNA CTD PMID:25658374 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Avpr1a arginine vasopressin receptor 1A multiple interactions ISO [NOTCH4 gene mutant form affects the susceptibility to Ozone] which affects the expression of AVPR1A mRNA CTD PMID:25658374 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G B2m beta-2 microglobulin decreases expression ISO Ozone results in decreased expression of B2M mRNA CTD PMID:12763052 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Bank1 B-cell scaffold protein with ankyrin repeats 1 decreases expression EXP Ozone results in decreased expression of BANK1 mRNA CTD PMID:28623178 NCBI chr 2:241,273,763...241,545,527
Ensembl chr 2:241,273,763...241,545,250
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
EXP [Ozone co-treated with Chlorine] results in decreased expression of BAX mRNA
Ozone results in increased expression of BAX protein
CTD PMID:18636392, PMID:23988432 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 increases expression EXP Ozone results in increased expression of BBOX1 mRNA CTD PMID:25838073 NCBI chr 3:101,425,684...101,474,848
Ensembl chr 3:101,427,055...101,474,890
JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member increases expression EXP Ozone results in increased expression of BCAR1 mRNA CTD PMID:16330353 NCBI chr19:43,932,543...43,967,452
Ensembl chr19:43,932,554...43,955,783
JBrowse link
G Bcas2 BCAS2, pre-mRNA processing factor multiple interactions ISO pyrazolanthrone inhibits the reaction [Ozone results in increased expression of BCAS2 mRNA] CTD PMID:17460151 NCBI chr 2:205,662,633...205,670,514
Ensembl chr 2:205,662,588...205,670,511
JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha decreases expression ISO Ozone results in decreased expression of BCKDHA mRNA CTD PMID:12763052 NCBI chr 1:82,423,291...82,452,094
Ensembl chr 1:82,423,277...82,452,281
JBrowse link
G Bcl10 BCL10, immune signaling adaptor increases expression
multiple interactions
ISO Ozone results in increased expression of BCL10 mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of BCL10 mRNA
CTD PMID:31476115 NCBI chr 2:251,805,392...251,814,957
Ensembl chr 2:251,805,392...251,814,957
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP Ozone results in increased expression of BCL2 protein CTD PMID:23988432 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
multiple interactions
ISO Ozone results in increased expression of BCL2L1 mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of BCL2L1 mRNA
CTD PMID:31476115 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l15 BCL2-like 15 multiple interactions ISO [NOTCH4 gene mutant form affects the susceptibility to Ozone] which affects the expression of BCL2L15 mRNA CTD PMID:25658374 NCBI chr 2:206,307,778...206,319,662
Ensembl chr 2:206,314,213...206,319,332
JBrowse link
G Bcl3 BCL3, transcription coactivator multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of BCL3 mRNA CTD PMID:25658374 NCBI chr 1:80,730,758...80,745,273
Ensembl chr 1:80,730,499...80,744,831
JBrowse link
G Bcl6 BCL6, transcription repressor decreases expression
multiple interactions
ISO Ozone results in decreased expression of BCL6 mRNA
[Aripiprazole co-treated with Ozone] results in decreased expression of BCL6 mRNA
CTD PMID:31476115 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Bcl9l BCL9 like decreases expression ISO Ozone results in decreased expression of BCL9L mRNA CTD PMID:31626304 NCBI chr 8:48,805,684...48,835,794
Ensembl chr 8:48,805,684...48,834,312
JBrowse link
G Bdkrb2 bradykinin receptor B2 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of BDKRB2 mRNA CTD PMID:18636392 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression
multiple interactions
ISO
EXP
Ozone results in increased expression of BDNF mRNA
[Ozone co-treated with Vehicle Emissions] results in increased expression of BDNF mRNA
CTD PMID:16716893, PMID:17095637, PMID:23358141 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 increases expression EXP Ozone results in increased expression of BECN1 protein CTD PMID:22727909 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression EXP Ozone results in increased expression of BHLHE40 mRNA CTD PMID:28623178 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Bicd1 BICD cargo adaptor 1 decreases expression ISO Ozone results in decreased expression of BICD1 mRNA CTD PMID:31626304 NCBI chr 4:184,018,845...184,167,628
Ensembl chr 4:184,019,087...184,165,540
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
increases expression
ISO [Aripiprazole co-treated with Ozone] results in increased expression of BID mRNA
Ozone results in increased expression of BID mRNA
CTD PMID:31476115 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bin1 bridging integrator 1 decreases expression EXP Ozone results in decreased expression of BIN1 mRNA CTD PMID:26667333 NCBI chr18:25,163,575...25,222,139
Ensembl chr18:25,163,561...25,222,135
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
increases expression
ISO TTPA protein affects the reaction [Ozone results in increased expression of BIRC5 mRNA] CTD PMID:12763052, PMID:19555225 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger decreases expression EXP Ozone results in decreased expression of BMI1 mRNA CTD PMID:26667334 NCBI chr17:85,360,439...85,370,283
Ensembl chr17:85,364,483...85,368,208
JBrowse link
G Bmp4 bone morphogenetic protein 4 multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of BMP4 mRNA CTD PMID:18636392 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bmp7 bone morphogenetic protein 7 decreases expression EXP Ozone results in decreased expression of BMP7 mRNA CTD PMID:28623178 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Bnip3l BCL2 interacting protein 3 like decreases expression ISO Ozone results in decreased expression of BNIP3L mRNA CTD PMID:12763052 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G Bpgm bisphosphoglycerate mutase decreases expression ISO Ozone results in decreased expression of BPGM mRNA CTD PMID:16183385 NCBI chr 4:61,912,210...61,940,697
Ensembl chr 4:61,912,210...61,940,696
JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression
multiple interactions
ISO Ozone results in decreased expression of BRCA1 mRNA
[NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of BRCA1 mRNA
CTD PMID:24336422, PMID:25658374 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Brs3 bombesin receptor subtype 3 multiple interactions
increases expression
ISO Ozone promotes the reaction [PPARA protein binds to BRS3 promoter]; Ozone promotes the reaction [TFAP2A protein binds to BRS3 promoter]; PPARA protein affects the reaction [Ozone results in increased expression of BRS3 mRNA]; TFAP2A protein affects the reaction [Ozone results in increased expression of BRS3 mRNA] CTD PMID:16426703, PMID:17355223 NCBI chr  X:159,484,953...159,510,944
Ensembl chr  X:159,505,344...159,511,021
JBrowse link
G Brwd3 bromodomain and WD repeat domain containing 3 multiple interactions ISO TTPA protein affects the reaction [Ozone results in increased expression of BRWD3 mRNA] CTD PMID:19555225 NCBI chr  X:79,817,968...79,909,891
Ensembl chr  X:79,824,782...79,909,678
JBrowse link
G Btg4 BTG anti-proliferation factor 4 decreases expression ISO Ozone results in decreased expression of BTG4 mRNA CTD PMID:31626304 NCBI chr 8:55,408,917...55,508,100
Ensembl chr 8:55,504,359...55,508,259
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase multiple interactions ISO TTPA protein affects the reaction [Ozone results in increased expression of BUB1 mRNA] CTD PMID:19555225 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B decreases expression
multiple interactions
ISO Ozone results in decreased expression of BUB1B mRNA
[NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of BUB1B mRNA
CTD PMID:24336422, PMID:25658374 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G Bzw1 basic leucine zipper and W2 domains 1 increases expression ISO Ozone results in increased expression of BZW1 mRNA CTD PMID:19555225 NCBI chr 9:65,279,675...65,293,471
Ensembl chr 9:65,279,675...65,291,651
JBrowse link
G C1qtnf2 C1q and TNF related 2 decreases expression ISO Ozone results in decreased expression of C1QTNF2 mRNA CTD PMID:17095637 NCBI chr10:29,067,102...29,084,035
Ensembl chr10:29,067,102...29,084,035
JBrowse link
G C1r complement C1r multiple interactions
decreases expression
ISO Aripiprazole promotes the reaction [Ozone results in decreased expression of C1R mRNA] CTD PMID:31476115 NCBI chr 4:157,126,060...157,136,825
Ensembl chr 4:157,125,998...157,136,829
JBrowse link
G C2 complement C2 increases expression
multiple interactions
ISO Ozone results in increased expression of C2 mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of C2 mRNA
CTD PMID:31476115 NCBI chr20:4,542,340...4,561,152
Ensembl chr20:4,542,340...4,561,152
JBrowse link
G C3 complement C3 multiple interactions
decreases expression
increases expression
ISO
EXP
C3 protein affects the susceptibility to [Ozone co-treated with Methacholine Chloride]; cobra venom factor inhibits the reaction [Ozone results in increased expression of C3 protein]
Ozone results in decreased expression of C3 mRNA
CTD PMID:14701711, PMID:16716893 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C4bpa complement component 4 binding protein, alpha decreases expression EXP Ozone results in decreased expression of C4BPA mRNA CTD PMID:16716893 NCBI chr13:47,342,090...47,377,580
Ensembl chr13:47,342,079...47,377,703
JBrowse link
G C5ar1 complement C5a receptor 1 multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of C5AR1 mRNA CTD PMID:18636392 NCBI chr 1:78,186,777...78,195,132
Ensembl chr 1:78,186,776...78,195,328
JBrowse link
G Ca3 carbonic anhydrase 3 multiple interactions
decreases expression
EXP
ISO
[Ozone co-treated with Chlorine] affects the expression of CA3 mRNA
Ozone results in decreased expression of CAR3 mRNA
CTD PMID:12763052, PMID:18636392 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Ca4 carbonic anhydrase 4 decreases expression EXP Ozone results in decreased expression of CA4 mRNA CTD PMID:31397875 NCBI chr10:72,272,286...72,281,069
Ensembl chr10:72,272,248...72,281,067
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of CACNA1A mRNA CTD PMID:18636392 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of CACNA1B mRNA CTD PMID:18636392 NCBI chr 3:1,740,026...1,924,959
Ensembl chr 3:1,740,024...1,924,827
JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I decreases expression ISO Ozone results in decreased expression of CACNA1I mRNA CTD PMID:31626304 NCBI chr 7:121,521,787...121,619,300
Ensembl chr 7:121,511,097...121,619,283
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of CACNB3 mRNA CTD PMID:18636392 NCBI chr 7:140,311,120...140,324,902
Ensembl chr 7:140,315,368...140,324,902
JBrowse link
G Calca calcitonin-related polypeptide alpha increases expression
multiple interactions
ISO Ozone results in increased expression of CALCA mRNA
TTPA protein affects the reaction [Ozone results in increased expression of CALCA mRNA]
CTD PMID:17095637, PMID:19555225 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Calcrl calcitonin receptor like receptor decreases expression ISO Ozone results in decreased expression of CALCRL mRNA CTD PMID:17095637, PMID:17460151 NCBI chr 3:71,747,938...71,845,487
Ensembl chr 3:71,747,956...71,845,232
JBrowse link
G Calm3 calmodulin 3 decreases expression EXP Ozone results in decreased expression of CALM3 mRNA CTD PMID:16330353 NCBI chr 1:78,844,520...78,851,628
Ensembl chr 1:78,843,080...78,851,719
JBrowse link
G Calml3 calmodulin-like 3 decreases expression ISO Ozone results in decreased expression of CALML3 mRNA CTD PMID:31626304 NCBI chr17:70,070,458...70,073,697
Ensembl chr17:70,072,156...70,073,530
JBrowse link
G Calml5 calmodulin-like 5 decreases expression ISO Ozone results in decreased expression of CALM4 mRNA CTD PMID:12763052 NCBI chr17:70,044,956...70,045,886 JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV decreases expression EXP Ozone results in decreased expression of CAMK4 mRNA CTD PMID:16330353 NCBI chr18:25,746,878...25,975,962
Ensembl chr18:25,749,098...25,965,957
JBrowse link
G Card9 caspase recruitment domain family, member 9 decreases expression EXP Ozone results in decreased expression of CARD9 mRNA CTD PMID:26667333 NCBI chr 3:3,798,346...3,806,841
Ensembl chr 3:3,798,347...3,806,713
JBrowse link
G Carmil1 capping protein regulator and myosin 1 linker 1 increases expression ISO Ozone results in increased expression of CARMIL1 mRNA CTD PMID:31626304 NCBI chr17:43,050,282...43,339,403
Ensembl chr17:43,050,789...43,339,403
JBrowse link
G Cartpt CART prepropeptide multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of CARTPT mRNA CTD PMID:18636392 NCBI chr 2:30,125,249...30,127,408
Ensembl chr 2:30,125,249...30,127,269
JBrowse link
G Casp3 caspase 3 multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of CASP3 mRNA CTD PMID:18636392 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 increases cleavage EXP Ozone results in increased cleavage of CASP9 protein CTD PMID:22727909 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Casr calcium-sensing receptor multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of CASR mRNA CTD PMID:18636392 NCBI chr11:67,188,204...67,262,261
Ensembl chr11:67,188,630...67,258,771
JBrowse link
G Cast calpastatin multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of CAST mRNA CTD PMID:18636392 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Cat catalase decreases expression ISO Ozone results in decreased expression of CAT mRNA CTD PMID:12763052 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 decreases expression
multiple interactions
ISO Ozone results in decreased expression of CAV1 mRNA; Ozone results in decreased expression of CAV1 protein
TNF protein affects the reaction [Ozone results in decreased expression of CAV1 protein]
CTD PMID:12763052, PMID:18207479 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cavin2 caveolae associated protein 2 decreases expression
increases expression
ISO
EXP
Ozone results in decreased expression of CAVIN2 mRNA
Ozone results in increased expression of CAVIN2 mRNA
CTD PMID:12763052, PMID:28623178 NCBI chr 9:55,244,136...55,256,153
Ensembl chr 9:55,243,255...55,256,340
JBrowse link
G Cby1 chibby family member 1, beta catenin antagonist decreases expression ISO Ozone results in decreased expression of CBY1 mRNA CTD PMID:17460151 NCBI chr 7:120,891,930...120,898,318
Ensembl chr 7:120,891,940...120,897,687
JBrowse link
G Cc2d2a coiled-coil and C2 domain containing 2A decreases expression EXP Ozone results in decreased expression of CC2D2A mRNA CTD PMID:28623178 NCBI chr14:71,895,128...71,979,452
Ensembl chr14:71,895,246...71,973,419
JBrowse link
G Ccdc114 coiled-coil domain containing 114 decreases expression EXP Ozone results in decreased expression of CCDC114 mRNA CTD PMID:28623178 NCBI chr 1:101,904,042...101,932,999
Ensembl chr 1:101,906,903...101,932,998
JBrowse link
G Ccdc117 coiled-coil domain containing 117 increases expression ISO Ozone results in increased expression of CCDC117 mRNA CTD PMID:21543283 NCBI chr14:85,763,396...85,772,762
Ensembl chr14:85,763,397...85,772,762
JBrowse link
G Ccdc142 coiled-coil domain containing 142 decreases expression EXP Ozone results in decreased expression of CCDC142 mRNA CTD PMID:28623178 NCBI chr 4:113,933,466...113,941,297
Ensembl chr 4:114,800,900...114,807,204
Ensembl chr 4:114,800,900...114,807,204
JBrowse link
G Ccdc40 coiled-coil domain containing 40 decreases expression EXP Ozone results in decreased expression of CCDC40 mRNA CTD PMID:28623178 NCBI chr10:108,055,270...108,393,408
Ensembl chr10:108,340,240...108,372,862
JBrowse link
G Cchcr1 coiled-coil alpha-helical rod protein 1 decreases expression EXP Ozone results in decreased expression of CCHCR1 mRNA CTD PMID:28623178 NCBI chr20:3,730,968...3,745,721
Ensembl chr20:3,730,955...3,740,009
JBrowse link
G Cckbr cholecystokinin B receptor multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of CCKBR mRNA CTD PMID:18636392 NCBI chr 1:170,262,218...170,272,298
Ensembl chr 1:170,262,156...170,272,298
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 multiple interactions
increases secretion
increases expression
ISO
EXP
[LEP gene mutant form results in increased susceptibility to Ozone] which results in increased expression of CCL11 protein; IL1R1 gene mutant form affects the reaction [Ozone results in increased expression of CCL11 protein]; LEP gene mutant form promotes the reaction [Ozone results in increased expression of CCL11 protein]; LEPR gene mutant form promotes the reaction [Ozone results in increased expression of CCL11 protein]; SCGB1A1 protein affects the reaction [Ozone results in increased expression of CCL11 mRNA]
Ozone results in increased secretion of CCL11 protein
Ozone results in increased expression of CCL11 mRNA; Ozone results in increased expression of CCL11 protein
CTD PMID:9458816, PMID:10027076, PMID:10027081, PMID:10715624, PMID:11777981, PMID:12794034, PMID:15516495, PMID:16373670, PMID:17460151, PMID:17575079, PMID:18929643, PMID:20417186, PMID:26342085, PMID:27472835, PMID:30848106, PMID:31626304 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 multiple interactions
increases expression
ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CCL17 mRNA; [NOTCH4 gene mutant form affects the susceptibility to Ozone] which affects the expression of CCL17 mRNA
Ozone results in increased expression of CCL17 mRNA
CTD PMID:12763052, PMID:25658374, PMID:26342085, PMID:30848106 NCBI chr19:10,619,220...10,620,671
Ensembl chr19:10,619,220...10,620,671
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 multiple interactions
increases expression
ISO [Aripiprazole co-treated with Ozone] results in increased expression of CCL19 mRNA
Ozone results in increased expression of CCL19 mRNA
CTD PMID:26342085, PMID:31476115 NCBI chr 5:58,181,025...58,182,969
Ensembl chr 5:58,181,026...58,183,017
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases expression
increases expression
EXP
ISO
[Ozone co-treated with Particulate Matter] results in increased expression of CCL2 mRNA; Metyrapone inhibits the reaction [Ozone results in increased expression of CCL2 mRNA]; Metyrapone inhibits the reaction [Ozone results in increased expression of CCL2 protein]
[Aripiprazole co-treated with Ozone] results in increased expression of CCL2 mRNA
Ozone results in decreased expression of CCL2 mRNA
Ozone results in increased expression of CCL2 mRNA; Ozone results in increased expression of CCL2 protein
[Acetaminophen co-treated with Ozone] results in increased expression of CCL2 mRNA; [NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of CCL2 mRNA; [Ozone co-treated with Acetaminophen] results in increased expression of CCL2 protein; CPE gene mutant form promotes the reaction [Ozone results in increased expression of CCL2 protein]; Docosahexaenoic Acids metabolite inhibits the reaction [Ozone results in increased expression of CCL2 mRNA]; Endotoxins promotes the reaction [Ozone results in increased expression of CCL2 mRNA]; Ozone inhibits the reaction [Acetaminophen results in increased expression of CCL2 mRNA]; pyrazolanthrone promotes the reaction [Ozone results in increased expression of CCL2 mRNA]
CTD PMID:9458799, PMID:11498801, PMID:12217210, PMID:12763052, PMID:14754758, PMID:15371095, PMID:16002559, PMID:16716893, PMID:17307210, PMID:17460151, PMID:17575079, PMID:18929643, PMID:20123758, PMID:22727909, PMID:23805001, PMID:25658374, PMID:27037194, PMID:27206323, PMID:29471542, PMID:29767793, PMID:30848106, PMID:31476115 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression
multiple interactions
ISO Ozone results in increased expression of CCL20 mRNA; Ozone results in increased expression of CCL20 protein
[Aripiprazole co-treated with Ozone] results in increased expression of CCL20 mRNA
IL13 protein affects the reaction [Ozone results in increased expression of CCL20 protein]; TNFRSF1B affects the reaction [Ozone results in increased expression of CCL20 protein]
CTD PMID:17095637, PMID:18417511, PMID:23434795, PMID:26342085, PMID:30848106, PMID:31476115 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 multiple interactions
increases expression
ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of CCL22 mRNA
Ozone results in increased expression of CCL22 mRNA
Aripiprazole inhibits the reaction [Ozone results in increased expression of CCL22 mRNA]
CTD PMID:25658374, PMID:26342085, PMID:31476115 NCBI chr19:10,674,189...10,681,145
Ensembl chr19:10,674,189...10,681,145
JBrowse link
G Ccl24 C-C motif chemokine ligand 24 increases expression ISO Ozone results in increased expression of CCL24 mRNA CTD PMID:31626304 NCBI chr12:24,131,529...24,152,626
Ensembl chr12:24,148,567...24,152,625
JBrowse link
G Ccl25 C-C motif chemokine ligand 25 decreases expression ISO Ozone results in decreased expression of CCL25 mRNA CTD PMID:26342085 NCBI chr12:2,429,492...2,438,928
Ensembl chr12:2,429,509...2,438,817
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression
multiple interactions
ISO Ozone results in increased expression of CCL3 mRNA; Ozone results in increased expression of CCL3 protein
[Aripiprazole co-treated with Ozone] results in increased expression of CCL3 mRNA
SCGB1A1 protein affects the reaction [Ozone results in increased expression of CCL3 mRNA]
CTD PMID:10027076, PMID:10027081, PMID:10715624, PMID:11777981, PMID:18926814, PMID:18929643, PMID:26342085, PMID:27679563, PMID:31476115 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions
decreases expression
increases expression
ISO [LEP gene mutant form results in increased susceptibility to Ozone] which results in increased expression of CCL4 protein; IL1RL1 protein affects the reaction [[LEP gene mutant form results in increased susceptibility to Ozone] which results in increased expression of CCL4 protein]
Ozone results in decreased expression of CCL4 mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of CCL4 mRNA
Ozone results in increased expression of CCL4 mRNA
Ozone results in increased expression of CCL4 protein
CTD PMID:26342085, PMID:27472835, PMID:27679563, PMID:31476115 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression
increases expression
multiple interactions
ISO Ozone results in decreased expression of CCL5 mRNA
Ozone results in increased expression of CCL5 mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of CCL5 mRNA
[LEP gene mutant form results in increased susceptibility to Ozone] which results in increased expression of CCL5 protein
CTD PMID:12763052, PMID:27472835, PMID:31476115 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases response to substance
multiple interactions
increases expression
ISO CCL7 protein results in increased susceptibility to Ozone
[NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of CCL7 mRNA; [NOTCH4 gene mutant form affects the susceptibility to Ozone] which affects the expression of CCL7 mRNA
Ozone results in increased expression of CCL7 mRNA; Ozone results in increased expression of CCL7 protein
CTD PMID:11777981, PMID:18929643, PMID:25658374, PMID:30848106 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccn5 cellular communication network factor 5 decreases expression ISO Ozone results in decreased expression of CCN5 mRNA CTD PMID:17095637, PMID:19555225 NCBI chr 3:160,207,969...160,219,316
Ensembl chr 3:160,207,913...160,219,331
JBrowse link
G Ccna2 cyclin A2 multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CCNA2 mRNA; TTPA protein affects the reaction [Ozone results in increased expression of CCNA2 mRNA] CTD PMID:19555225, PMID:25658374 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 decreases expression
increases expression
multiple interactions
ISO Ozone results in decreased expression of CCNB1 mRNA; Ozone results in decreased expression of CCNB1 protein
Ozone results in increased expression of CCNB1 mRNA
[NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of CCNB1 mRNA; TTPA protein affects the reaction [Ozone results in increased expression of CCNB1 mRNA]
CTD PMID:16183385, PMID:19555225, PMID:25658374 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnb2 cyclin B2 multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CCNB2 mRNA; TTPA protein affects the reaction [Ozone results in increased expression of CCNB2 mRNA] CTD PMID:19555225, PMID:25658374 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Ccnc cyclin C multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of CCNC mRNA CTD PMID:18636392 NCBI chr 5:35,865,598...35,883,732
Ensembl chr 5:35,865,605...35,883,706
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
EXP [Ozone co-treated with Chlorine] results in decreased expression of CCND1 mRNA
Ozone results in decreased expression of CCND1 mRNA
CTD PMID:18636392, PMID:31397875 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd3 cyclin D3 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of CCND3 mRNA CTD PMID:18636392 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccne1 cyclin E1 increases expression
decreases expression
EXP
ISO
Ozone results in increased expression of CCNE1 mRNA
Ozone results in decreased expression of CCNE1 mRNA
CTD PMID:16330353, PMID:24336422 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Ccne2 cyclin E2 increases expression ISO Ozone results in increased expression of CCNE2 mRNA CTD PMID:25658374 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Ccnf cyclin F decreases expression ISO Ozone results in decreased expression of CCNF mRNA CTD PMID:24336422 NCBI chr10:13,594,687...13,619,935
Ensembl chr10:13,594,687...13,619,935
JBrowse link
G Ccng1 cyclin G1 multiple interactions
increases expression
EXP [Ozone co-treated with Chlorine] results in decreased expression of CCNG1 mRNA
Ozone results in increased expression of CCNG1 mRNA
CTD PMID:16330353, PMID:18636392 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 increases expression ISO Ozone results in increased expression of CCR1 protein CTD PMID:27679563 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 decreases response to substance
decreases expression
ISO CCR2 gene mutant form results in decreased susceptibility to Ozone
Ozone results in decreased expression of CCR2 mRNA
CTD PMID:26342085, PMID:27837169
G Ccr3 C-C motif chemokine receptor 3 increases expression
multiple interactions
ISO Ozone results in increased expression of CCR3 protein
Ozone results in increased expression of CCR3 mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of CCR3 mRNA
CTD PMID:11777981, PMID:31476115 NCBI chr 8:133,026,539...133,040,999
Ensembl chr 8:133,029,625...133,040,997
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 decreases expression ISO Ozone results in decreased expression of CCR4 mRNA CTD PMID:26342085 NCBI chr 8:122,530,152...122,535,959
Ensembl chr 8:122,530,624...122,532,070
JBrowse link
G Cd14 CD14 molecule increases expression
multiple interactions
ISO Ozone results in increased expression of CD14 mRNA
[NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CD14 mRNA
CTD PMID:17095637, PMID:25658374, PMID:26342085, PMID:30848106 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd163 CD163 molecule increases expression ISO Ozone results in increased expression of CD163 mRNA CTD PMID:17095637 NCBI chr 4:156,752,063...156,785,467
Ensembl chr 4:156,752,082...156,785,467
JBrowse link
G Cd177 CD177 molecule increases expression ISO Ozone results in increased expression of CD177 mRNA CTD PMID:31626304 NCBI chr 1:82,964,683...82,987,306
Ensembl chr 1:82,964,683...82,987,253
JBrowse link
G Cd180 CD180 molecule decreases expression EXP Ozone results in decreased expression of CD180 mRNA CTD PMID:31397875 NCBI chr 2:32,820,275...32,833,223
Ensembl chr 2:32,820,322...32,833,125
JBrowse link
G Cd19 CD19 molecule multiple interactions
decreases expression
ISO
EXP
TTPA protein affects the reaction [Ozone results in decreased expression of CD19 mRNA] CTD PMID:19555225, PMID:28623178 NCBI chr 1:197,815,422...197,822,123
Ensembl chr 1:197,815,413...197,821,936
JBrowse link
G Cd1d1 CD1d1 molecule decreases expression EXP Ozone results in decreased expression of CD1D1 mRNA CTD PMID:16330353 NCBI chr 2:186,330,298...186,333,805
Ensembl chr 2:186,330,298...186,333,805
JBrowse link
G Cd200r1l CD200 receptor 1-like multiple interactions ISO [NOTCH4 gene mutant form affects the susceptibility to Ozone] which affects the expression of CD200R4 mRNA CTD PMID:25658374 NCBI chr11:60,803,856...60,828,979
Ensembl chr11:60,804,311...60,819,249
JBrowse link
G Cd209a CD209a antigen decreases expression ISO Ozone results in decreased expression of CD209A mRNA CTD PMID:17095637 NCBI chr12:2,341,960...2,347,543
Ensembl chr12:2,341,960...2,347,543
JBrowse link
G Cd22 CD22 molecule decreases expression EXP Ozone results in decreased expression of CD22 mRNA CTD PMID:28623178 NCBI chr 1:89,313,475...89,329,902
Ensembl chr 1:89,314,558...89,329,418
JBrowse link
G Cd24 CD24 molecule increases expression EXP Ozone results in increased expression of CD24 mRNA CTD PMID:16330353 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link
G Cd247 Cd247 molecule increases expression EXP Ozone results in increased expression of CD3Z mRNA CTD PMID:16330353 NCBI chr13:83,996,045...84,071,408
Ensembl chr13:83,996,080...84,071,400
JBrowse link
G Cd274 CD274 molecule multiple interactions
increases expression
ISO [Aripiprazole co-treated with Ozone] results in increased expression of CD274 mRNA
Ozone results in increased expression of CD274 mRNA
CTD PMID:31476115 NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943
JBrowse link
G Cd33 CD33 molecule increases expression
multiple interactions
ISO Ozone results in increased expression of CD33 mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of CD33 mRNA
CTD PMID:31476115 NCBI chr 1:98,388,811...98,403,539
Ensembl chr 1:98,398,660...98,402,968
JBrowse link
G Cd36 CD36 molecule decreases response to substance ISO CD36 gene mutant form results in decreased susceptibility to Ozone CTD PMID:23650127 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd37 CD37 molecule decreases expression ISO Ozone results in decreased expression of CD37 mRNA CTD PMID:12763052 NCBI chr 1:101,230,470...101,236,061
Ensembl chr 1:101,230,533...101,236,065
JBrowse link
G Cd4 Cd4 molecule multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of CD4 mRNA CTD PMID:18636392 NCBI chr 4:157,381,862...157,408,357
Ensembl chr 4:157,383,052...157,408,176
JBrowse link
G Cd40 CD40 molecule decreases expression ISO Ozone results in decreased expression of CD40 mRNA CTD PMID:26342085 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd40lg CD40 ligand decreases expression ISO Ozone results in decreased expression of CD40LG mRNA CTD PMID:26342085 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression
multiple interactions
ISO
EXP
Ozone results in increased expression of CD44 mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of CD44 mRNA
[Ozone co-treated with Chlorine] affects the expression of CD44 mRNA
CTD PMID:12763052, PMID:18636392, PMID:31476115 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd47 Cd47 molecule decreases expression
increases expression
ISO
EXP
Ozone results in decreased expression of CD47 mRNA
Ozone results in increased expression of CD47 mRNA
CTD PMID:12763052, PMID:16330353 NCBI chr11:53,511,485...53,575,754
Ensembl chr11:53,514,595...53,575,175
JBrowse link
G Cd5 Cd5 molecule increases expression EXP Ozone results in increased expression of CD5 mRNA CTD PMID:16330353 NCBI chr 1:226,770,912...226,791,861
Ensembl chr 1:226,770,744...226,791,879
JBrowse link
G Cd52 CD52 molecule decreases expression ISO Ozone results in decreased expression of CD52 mRNA CTD PMID:17095637 NCBI chr 5:152,322,910...152,324,469
Ensembl chr 5:152,322,916...152,324,469
JBrowse link
G Cd70 Cd70 molecule multiple interactions
increases expression
ISO [Aripiprazole co-treated with Ozone] results in increased expression of CD70 mRNA
Ozone results in increased expression of CD70 mRNA
CTD PMID:31476115 NCBI chr 9:9,842,585...9,845,728
Ensembl chr 9:9,842,585...9,845,728
JBrowse link
G Cd79a CD79a molecule decreases expression ISO Ozone results in decreased expression of CD79A mRNA CTD PMID:12763052 NCBI chr 1:81,763,609...81,768,039
Ensembl chr 1:81,763,614...81,767,980
JBrowse link
G Cd83 CD83 molecule increases expression
decreases expression
multiple interactions
ISO Ozone results in increased expression of CD83 mRNA
Ozone results in decreased expression of CD83 mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of CD83 mRNA
CTD PMID:31476115, PMID:31626304 NCBI chr17:24,416,651...24,435,790
Ensembl chr17:24,416,651...24,435,790
JBrowse link
G Cd86 CD86 molecule increases expression EXP Ozone results in increased expression of CD86 protein CTD PMID:15036748 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cd8b CD8b molecule decreases expression ISO Ozone results in decreased expression of CD8B1 mRNA CTD PMID:12763052 NCBI chr 4:99,185,960...99,201,887
Ensembl chr 4:99,185,885...99,202,023
JBrowse link
G Cd9 CD9 molecule multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of CD9 mRNA CTD PMID:18636392 NCBI chr 4:157,977,163...158,010,091
Ensembl chr 4:157,977,162...158,010,166
JBrowse link
G Cd93 CD93 molecule decreases expression EXP Ozone results in decreased expression of CD93 mRNA CTD PMID:31397875 NCBI chr 3:142,778,798...142,783,774
Ensembl chr 3:142,778,770...142,783,774
JBrowse link
G Cdc20 cell division cycle 20 increases expression
multiple interactions
ISO Ozone results in increased expression of CDC20 mRNA
[NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of CDC20 mRNA
CTD PMID:19555225, PMID:25658374 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdc25b cell division cycle 25B multiple interactions
increases expression
EXP [Ozone co-treated with Chlorine] results in increased expression of CDC25B mRNA
Ozone results in increased expression of CDC25B mRNA
CTD PMID:16330353, PMID:18636392 NCBI chr 3:123,731,539...123,741,696
Ensembl chr 3:123,731,539...123,741,339
JBrowse link
G Cdc45 cell division cycle 45 decreases expression ISO Ozone results in decreased expression of CDC45 mRNA CTD PMID:24336422 NCBI chr11:86,328,785...86,354,099
Ensembl chr11:86,329,012...86,358,453
JBrowse link
G Cdc6 cell division cycle 6 increases expression
multiple interactions
ISO Ozone results in increased expression of CDC6 mRNA
[NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of CDC6 mRNA
CTD PMID:19555225, PMID:25658374 NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402
JBrowse link
G Cdca2 cell division cycle associated 2 decreases expression ISO Ozone results in decreased expression of CDCA2 mRNA CTD PMID:24336422 NCBI chr15:44,365,396...44,411,601
Ensembl chr15:44,365,405...44,411,004
JBrowse link
G Cdca3 cell division cycle associated 3 multiple interactions
increases expression
ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of CDCA3 mRNA; TTPA protein affects the reaction [Ozone results in increased expression of CDCA3 mRNA] CTD PMID:19555225, PMID:25658374 NCBI chr 4:157,347,876...157,351,889
Ensembl chr 4:157,348,020...157,351,604
JBrowse link
G Cdca5 cell division cycle associated 5 multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CDCA5 mRNA CTD PMID:25658374 NCBI chr 1:221,448,661...221,462,235
Ensembl chr 1:221,448,661...221,462,233
JBrowse link
G Cdca8 cell division cycle associated 8 decreases expression
multiple interactions
ISO Ozone results in decreased expression of CDCA8 mRNA
[NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CDCA8 mRNA
CTD PMID:24336422, PMID:25658374 NCBI chr 5:142,911,310...142,933,536
Ensembl chr 5:142,911,305...142,933,526
JBrowse link
G Cdh13 cadherin 13 multiple interactions
affects response to substance
ISO [ADIPOQ protein binds to CDH13 protein] inhibits the reaction [Ozone results in increased expression of IL17A mRNA]; CDH13 gene mutant form promotes the reaction [Ozone results in increased expression of IL17A mRNA]; CDH13 gene mutant form promotes the reaction [Ozone results in increased expression of SAA3 mRNA]
CDH13 protein affects the susceptibility to Ozone
CTD PMID:23755285 NCBI chr19:50,848,793...51,971,618
Ensembl chr19:50,848,736...51,972,103
JBrowse link
G Cdh22 cadherin 22 multiple interactions
increases expression
EXP [Ozone co-treated with Chlorine] affects the expression of CDH22 mRNA
Ozone results in increased expression of CDH22 mRNA
CTD PMID:18636392, PMID:26667333 NCBI chr 3:161,574,993...161,971,102
Ensembl chr 3:161,575,631...161,917,285
JBrowse link
G Cdh26 cadherin 26 decreases expression ISO Ozone results in decreased expression of CDH26 mRNA CTD PMID:31626304 NCBI chr 3:173,969,004...174,020,867
Ensembl chr 3:173,969,273...174,019,766
JBrowse link
G Cdh5 cadherin 5 multiple interactions
increases expression
ISO Aripiprazole inhibits the reaction [Ozone results in increased expression of CDH5 mRNA] CTD PMID:31476115 NCBI chr19:1,025,122...1,074,333
Ensembl chr19:1,023,683...1,074,365
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression
increases expression
ISO Ozone results in decreased expression of CDK1 mRNA
Ozone results in increased expression of CDK1 mRNA
CTD PMID:12763052, PMID:19555225, PMID:24336422, PMID:25658374 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of CDK4 mRNA CTD PMID:18636392 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO
EXP
Ozone results in increased expression of CDKN1A mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of CDKN1A mRNA
[Ozone co-treated with Chlorine] affects the expression of CDKN1A mRNA
[Acetaminophen co-treated with Ozone] results in increased expression of CDKN1A mRNA
CTD PMID:17460151, PMID:18636392, PMID:20123758, PMID:28623178, PMID:28652203, PMID:31397875, PMID:31476115 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of CDKN2B mRNA CTD PMID:18636392 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 multiple interactions
increases expression
ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of CDKN3 mRNA
Ozone results in increased expression of CDKN3 mRNA
CTD PMID:25658374 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CDT1 mRNA CTD PMID:25658374 NCBI chr19:55,381,565...55,386,511
Ensembl chr19:55,381,565...55,386,511
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 increases expression EXP
ISO
Ozone results in increased expression of CEACAM1 mRNA CTD PMID:16330353, PMID:19555225, PMID:31476115 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Ceacam6 CEA cell adhesion molecule 6 increases expression ISO Ozone results in increased expression of CEACAM6 mRNA CTD PMID:31476115 NCBI chr 1:81,683,500...81,701,230
Ensembl chr 1:81,683,463...81,701,317
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases activity
increases expression
multiple interactions
ISO Ozone results in increased activity of CEBPB protein
Ozone results in increased expression of CEBPB mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of CEBPB mRNA
CTD PMID:9124608, PMID:16819095, PMID:26342085, PMID:31476115 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta decreases expression EXP Ozone results in decreased expression of CEBPD mRNA CTD PMID:16716893 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Cenpe centromere protein E multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CENPE mRNA CTD PMID:25658374 NCBI chr 2:240,395,974...240,454,785
Ensembl chr 2:240,396,152...240,454,747
JBrowse link
G Cenpf centromere protein F decreases expression
multiple interactions
ISO Ozone results in decreased expression of CENPF mRNA
[NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of CENPF mRNA
CTD PMID:24336422, PMID:25658374 NCBI chr13:108,132,499...108,178,609
Ensembl chr13:108,132,499...108,178,609
JBrowse link
G Cenph centromere protein H multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CENPH mRNA CTD PMID:25658374 NCBI chr 2:30,766,637...30,780,123
Ensembl chr 2:30,766,590...30,780,121
JBrowse link
G Cenpk centromere protein K decreases expression ISO Ozone results in decreased expression of CENPK mRNA CTD PMID:24336422 NCBI chr 2:34,312,766...34,373,945
Ensembl chr 2:34,312,766...34,335,776
JBrowse link
G Cenpn centromere protein N decreases expression ISO Ozone results in decreased expression of CENPN mRNA CTD PMID:24336422 NCBI chr19:49,457,461...49,479,989
Ensembl chr19:49,340,184...49,479,996
JBrowse link
G Cep55 centrosomal protein 55 multiple interactions
increases expression
ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CEP55 mRNA; TTPA protein affects the reaction [Ozone results in increased expression of CEP55 mRNA] CTD PMID:19555225, PMID:25658374 NCBI chr 1:256,745,251...256,760,794
Ensembl chr 1:256,745,288...256,760,796
JBrowse link
G Ces3a carboxylesterase 3a increases expression
multiple interactions
EXP
ISO
Ozone results in increased expression of CES3 mRNA
pyrazolanthrone inhibits the reaction [Ozone results in increased expression of CES3 mRNA]
CTD PMID:16330353, PMID:17460151 NCBI chr19:37,070,705...37,079,411 JBrowse link
G Cfap53 cilia and flagella associated protein 53 increases expression EXP Ozone results in increased expression of CFAP53 mRNA CTD PMID:28623178 NCBI chr18:70,263,290...70,330,420
Ensembl chr18:70,263,359...70,329,907
JBrowse link
G Cfap99 cilia and flagella associated protein 99 decreases expression EXP Ozone results in decreased expression of CFAP99 mRNA CTD PMID:28623178 NCBI chr14:81,685,428...81,725,165
Ensembl chr14:81,687,021...81,725,181
JBrowse link
G Cfb complement factor B multiple interactions
increases expression
ISO [Aripiprazole co-treated with Ozone] results in increased expression of CFB mRNA
Ozone results in increased expression of CFB mRNA
CTD PMID:31476115 NCBI chr20:4,536,206...4,542,073
Ensembl chr20:4,536,203...4,561,066
Ensembl chr20:4,536,203...4,561,066
JBrowse link
G Cfd complement factor D decreases expression ISO Ozone results in decreased expression of CFD mRNA CTD PMID:12763052 NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943
JBrowse link
G Cfl1 cofilin 1 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of CFL1 mRNA CTD PMID:18636392 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions
increases expression
decreases expression
ISO Acetylcysteine inhibits the reaction [Ozone results in decreased expression of CFTR mRNA]; Acetylcysteine inhibits the reaction [Ozone results in decreased expression of CFTR protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Ozone results in decreased expression of CFTR mRNA]; Ozone inhibits the reaction [Colforsin results in increased activity of CFTR protein]; pimagedine inhibits the reaction [Ozone results in decreased expression of CFTR mRNA]; pimagedine inhibits the reaction [Ozone results in decreased expression of CFTR protein]
Ozone results in increased expression of CFTR mRNA
Ozone results in decreased expression of CFTR mRNA; Ozone results in decreased expression of CFTR protein
CTD PMID:19061877, PMID:27206323 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Ch25h cholesterol 25-hydroxylase multiple interactions
increases expression
ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CH25H mRNA; TTPA protein affects the reaction [Ozone results in increased expression of CH25H mRNA] CTD PMID:17095637, PMID:19555225, PMID:25658374 NCBI chr 1:252,807,062...252,811,409
Ensembl chr 1:252,807,065...252,808,380
JBrowse link
G Chadl chondroadherin-like decreases expression ISO Ozone results in decreased expression of CHADL mRNA CTD PMID:24336422 NCBI chr 7:122,915,847...122,929,127
Ensembl chr 7:122,922,022...122,926,336
JBrowse link
G Chek1 checkpoint kinase 1 increases expression ISO Ozone results in increased expression of CHEK1 mRNA CTD PMID:19555225 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Chl1 cell adhesion molecule L1-like multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CHL1 mRNA CTD PMID:25658374 NCBI chr 4:70,269,414...70,331,313
Ensembl chr 4:70,252,366...70,330,803
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 decreases expression EXP Ozone results in decreased expression of CHRM2 mRNA CTD PMID:28623178 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of CHRNA1 mRNA CTD PMID:18636392 NCBI chr 3:60,445,657...60,460,724
Ensembl chr 3:60,445,666...60,460,724
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of CHRNA4 mRNA CTD PMID:18636392 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of CHRNA7 mRNA CTD PMID:25658374 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196
JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of CHRNB1 mRNA CTD PMID:18636392 NCBI chr10:56,390,671...56,403,255
Ensembl chr10:56,390,671...56,403,188
JBrowse link
G Cidec cell death-inducing DFFA-like effector c decreases expression ISO Ozone results in decreased expression of CIDEC mRNA CTD PMID:12763052 NCBI chr 4:145,377,482...145,390,497
Ensembl chr 4:145,377,431...145,390,497
JBrowse link
G Cip2a cellular inhibitor of PP2A decreases expression ISO Ozone results in decreased expression of CIP2A mRNA CTD PMID:24336422 NCBI chr11:54,373,794...54,404,704
Ensembl chr11:54,377,374...54,404,612
JBrowse link
G Cirbp cold inducible RNA binding protein increases expression ISO Ozone results in increased expression of CIRBP mRNA CTD PMID:17095637 NCBI chr 7:12,400,066...12,405,054
Ensembl chr 7:12,401,207...12,405,022
JBrowse link
G Ckap2 cytoskeleton associated protein 2 decreases expression
multiple interactions
ISO Ozone results in decreased expression of CKAP2 mRNA
[NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CKAP2 mRNA
CTD PMID:24336422, PMID:25658374 NCBI chr16:74,752,655...74,779,184
Ensembl chr16:74,752,655...74,779,184
JBrowse link
G Ckap2l cytoskeleton associated protein 2-like decreases expression
multiple interactions
ISO Ozone results in decreased expression of CKAP2L mRNA
[NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CKAP2L mRNA
CTD PMID:24336422, PMID:25658374 NCBI chr 3:121,796,221...121,822,352
Ensembl chr 3:121,796,238...121,822,436
JBrowse link
G Ckm creatine kinase, M-type decreases expression ISO Ozone results in decreased expression of CKM mRNA CTD PMID:12763052 NCBI chr 1:80,321,507...80,331,841
Ensembl chr 1:80,321,585...80,331,841
JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1 multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of CKMT1 mRNA CTD PMID:18636392 NCBI chr 3:113,318,559...113,324,459
Ensembl chr 3:113,318,563...113,324,461
JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 decreases expression ISO Ozone results in decreased expression of CKMT2 mRNA CTD PMID:12763052 NCBI chr 2:21,422,680...21,452,797
Ensembl chr 2:21,422,818...21,437,193
JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B increases expression
multiple interactions
ISO Ozone results in increased expression of CKS1B mRNA
[NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CKS1B mRNA; TTPA protein affects the reaction [Ozone results in increased expression of CKS1B mRNA]
CTD PMID:12763052, PMID:19555225, PMID:25658374 NCBI chr 2:188,740,564...188,745,144
Ensembl chr 2:188,740,573...188,745,144
JBrowse link
G Clcn3 chloride voltage-gated channel 3 increases expression
multiple interactions
ISO Ozone results in increased expression of CLCN3 mRNA
alpha-Tocopherol inhibits the reaction [Ozone results in increased expression of CLCN3 mRNA]
CTD PMID:27886375 NCBI chr16:32,448,821...32,520,649
Ensembl chr16:32,449,116...32,519,148
JBrowse link
G Clcn5 chloride voltage-gated channel 5 increases expression ISO Ozone results in increased expression of CLCN5 mRNA CTD PMID:12763052 NCBI chr  X:16,170,585...16,196,691
Ensembl chr  X:16,050,780...16,196,789
JBrowse link
G Clec12b C-type lectin domain family 12, member B increases expression EXP Ozone results in increased expression of CLEC12B mRNA CTD PMID:28623178 NCBI chr 4:163,140,883...163,157,996
Ensembl chr 4:163,141,132...163,157,744
JBrowse link
G Clec3b C-type lectin domain family 3, member B multiple interactions ISO [NOTCH4 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CLEC3B mRNA CTD PMID:25658374 NCBI chr 8:132,241,016...132,248,066
Ensembl chr 8:132,241,134...132,246,694
JBrowse link
G Clec5a C-type lectin domain containing 5A multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of CLEC5A mRNA CTD PMID:25658374 NCBI chr 4:68,810,330...68,819,921
Ensembl chr 4:68,808,359...68,819,928
JBrowse link
G Clip4 CAP-GLY domain containing linker protein family, member 4 multiple interactions ISO TTPA protein affects the reaction [Ozone results in increased expression of CLIP4 mRNA] CTD PMID:19555225 NCBI chr 6:23,222,020...23,316,962
Ensembl chr 6:23,222,021...23,316,962
JBrowse link
G Clspn claspin multiple interactions
increases expression
ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CLSPN mRNA
Ozone results in increased expression of CLSPN mRNA
CTD PMID:25658374, PMID:28652203 NCBI chr 5:144,577,670...144,617,507
Ensembl chr 5:144,581,427...144,616,335
JBrowse link
G Clu clusterin increases expression
multiple interactions
ISO
EXP
Ozone results in increased expression of CLU mRNA
[Ozone co-treated with Chlorine] results in decreased expression of CLU mRNA
CTD PMID:12763052, PMID:18636392 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cmklr1 chemerin chemokine-like receptor 1 multiple interactions
increases expression
decreases expression
EXP
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CMKLR1 mRNA
Ozone results in increased expression of CMKLR1 mRNA
Ozone results in decreased expression of CMKLR1 mRNA
CTD PMID:18636392, PMID:29471542, PMID:31626304 NCBI chr12:48,743,556...48,796,582
Ensembl chr12:48,789,261...48,793,553
JBrowse link
G Cnga2 cyclic nucleotide gated channel subunit alpha 2 increases expression ISO Ozone results in increased expression of CNGA2 mRNA CTD PMID:17095637 NCBI chr16:69,878,513...69,899,075 JBrowse link
G Cnn3 calponin 3 multiple interactions
increases expression
EXP
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CNN3 mRNA
Ozone results in increased expression of CNN3 mRNA
CTD PMID:18636392, PMID:31626304 NCBI chr 2:225,005,069...225,036,179
Ensembl chr 2:225,005,019...225,036,188
JBrowse link
G Cnpy1 canopy FGF signaling regulator 1 decreases expression ISO Ozone results in decreased expression of CNPY1 mRNA CTD PMID:31626304 NCBI chr 4:474,424...496,826
Ensembl chr 4:476,977...482,645
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of CNR1 mRNA CTD PMID:18636392 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO
EXP
Ozone results in increased expression of COL1A1 mRNA CTD PMID:8018336, PMID:9820643, PMID:16716893, PMID:31626304 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression EXP Ozone results in increased expression of COL1A2 mRNA CTD PMID:16716893 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Col26a1 collagen type XXVI alpha 1 chain decreases expression ISO Ozone results in decreased expression of COL26A1 mRNA CTD PMID:31626304 NCBI chr12:22,834,866...22,980,603
Ensembl chr12:22,835,019...22,980,603
JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression EXP
ISO
Ozone results in increased expression of COL3A1 mRNA CTD PMID:8018336, PMID:9820643, PMID:16716893 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Col5a1 collagen type V alpha 1 chain affects expression EXP Ozone affects the expression of COL5A1 mRNA CTD PMID:16716893 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
JBrowse link
G Col6a5 collagen type VI alpha 5 chain decreases expression ISO Ozone results in decreased expression of COL6A5 mRNA CTD PMID:31626304 NCBI chr 8:114,527,807...114,632,152
Ensembl chr 8:114,529,016...114,617,466
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 increases expression ISO Ozone results in increased expression of COX4I1 mRNA CTD PMID:27240593 NCBI chr19:54,245,958...54,252,198
Ensembl chr19:54,245,950...54,252,225
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A increases expression ISO Ozone results in increased expression of COX5A mRNA CTD PMID:27240593 NCBI chr 8:62,298,358...62,309,765
Ensembl chr 8:62,298,358...62,309,765
JBrowse link
G Cox7a1 cytochrome c oxidase subunit 7A1 decreases expression ISO Ozone results in decreased expression of COX7A1 mRNA CTD PMID:12763052 NCBI chr 1:88,619,619...88,650,672
Ensembl chr 1:91,071,493...91,074,294
Ensembl chr 1:91,071,493...91,074,294
JBrowse link
G Cpd carboxypeptidase D multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of CPD mRNA CTD PMID:18636392 NCBI chr10:63,325,764...63,389,811
Ensembl chr10:63,325,199...63,389,817
JBrowse link
G Cpe carboxypeptidase E affects response to substance
decreases expression
increases response to substance
multiple interactions
ISO CPE affects the susceptibility to Ozone
Ozone results in decreased expression of CPE mRNA
CPE gene mutant form results in increased susceptibility to Ozone
[CPE affects the susceptibility to Ozone] which affects the expression of CSF3 protein; [CPE affects the susceptibility to Ozone] which affects the expression of CXCL1 protein; [CPE affects the susceptibility to Ozone] which affects the expression of IL13 mRNA; [CPE affects the susceptibility to Ozone] which affects the expression of IL17A mRNA; [CPE affects the susceptibility to Ozone] which affects the expression of IL5 mRNA; [CPE affects the susceptibility to Ozone] which affects the expression of IL6 protein; [CPE affects the susceptibility to Ozone] which affects the expression of TNF protein; CPE gene mutant form promotes the reaction [Ozone results in increased expression of CCL2 protein]; CPE gene mutant form promotes the reaction [Ozone results in increased expression of CXCL1 protein]; CPE gene mutant form promotes the reaction [Ozone results in increased expression of CXCL2 protein]; CPE gene mutant form promotes the reaction [Ozone results in increased expression of IL6 protein]; TNFRSF1B affects the reaction [[CPE affects the susceptibility to Ozone] which affects the expression of IL5 mRNA]; TNFRSF1B affects the reaction [CPE affects the susceptibility to Ozone]
CTD PMID:12763052, PMID:16002559, PMID:23434795 NCBI chr16:26,906,716...27,014,811
Ensembl chr16:26,906,716...27,014,813
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A decreases expression
increases expression
ISO
EXP
Ozone results in decreased expression of CPT1A mRNA
Ozone results in increased expression of CPT1A mRNA
CTD PMID:16183385, PMID:16330353 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of CPT1B mRNA CTD PMID:18636392 NCBI chr 7:130,395,211...130,404,731
Ensembl chr 7:130,395,194...130,405,347
JBrowse link
G Cr1l complement C3b/C4b receptor 1 like multiple interactions ISO CR1L protein affects the reaction [Ozone results in increased expression of CXCL1 protein]; CR1L protein affects the reaction [Ozone results in increased expression of CXCL2 protein]; CR1L protein affects the reaction [Ozone results in increased expression of IL1B protein]; CR1L protein affects the reaction [Ozone results in increased expression of TNF protein] CTD PMID:14701711 NCBI chr13:113,824,886...113,872,097
Ensembl chr13:113,824,892...113,872,097
JBrowse link
G Cr2 complement C3d receptor 2 multiple interactions ISO TTPA protein affects the reaction [Ozone results in decreased expression of CR2 mRNA] CTD PMID:19555225 NCBI chr13:113,890,274...113,927,824
Ensembl chr13:113,890,272...113,927,877
JBrowse link
G Crat carnitine O-acetyltransferase decreases expression ISO Ozone results in decreased expression of CRAT mRNA CTD PMID:12763052 NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362
JBrowse link
G Creb5 cAMP responsive element binding protein 5 increases expression
multiple interactions
ISO Ozone results in increased expression of CREB5 mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of CREB5 mRNA
CTD PMID:31476115 NCBI chr 4:83,390,782...83,840,356
Ensembl chr 4:83,391,283...83,836,351
JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of CRHR2 mRNA CTD PMID:18636392 NCBI chr 4:85,286,371...85,329,374
Ensembl chr 4:85,286,372...85,329,362
JBrowse link
G Crk CRK proto-oncogene, adaptor protein multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of CRK mRNA CTD PMID:18636392 NCBI chr10:63,829,731...63,855,999
Ensembl chr10:63,829,807...63,852,780
JBrowse link
G Cryaa crystallin, alpha A decreases expression ISO Ozone results in decreased expression of CRYAA mRNA CTD PMID:31626304 NCBI chr20:10,438,444...10,442,189
Ensembl chr20:10,438,444...10,442,187
JBrowse link
G Cryab crystallin, alpha B increases expression EXP Ozone results in increased expression of CRYAB mRNA CTD PMID:31397875 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Csf1 colony stimulating factor 1 multiple interactions
decreases expression
increases expression
ISO [Aripiprazole co-treated with Ozone] results in increased expression of CSF1 mRNA
Ozone results in decreased expression of CSF1 mRNA
Ozone results in increased expression of CSF1 mRNA
CTD PMID:26342085, PMID:31476115 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of CSF1R mRNA CTD PMID:18636392 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions
increases expression
decreases expression
EXP
ISO
Ozone promotes the reaction [[CSF2 protein results in increased expression of ITGB2 protein] which results in increased abundance of Nitric Oxide]
[Aripiprazole co-treated with Ozone] results in increased expression of CSF2 mRNA
Ozone results in increased expression of CSF2 mRNA
Ozone results in decreased expression of CSF2 mRNA
Ozone results in increased expression of CSF2 protein
CTD PMID:8600936, PMID:16330353, PMID:18315731, PMID:31476115 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csf3 colony stimulating factor 3 multiple interactions
increases secretion
increases expression
EXP
ISO
[Ozone co-treated with Chlorine] results in increased expression of CSF3 mRNA
Ozone results in increased secretion of CSF3 protein
Ozone results in increased expression of CSF3 mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of CSF3 mRNA
[CPE affects the susceptibility to Ozone] which affects the expression of CSF3 protein; [LEP gene mutant form results in increased susceptibility to Ozone] which results in increased expression of CSF3 protein
Ozone results in increased expression of CSF3 protein
CTD PMID:18315731, PMID:18636392, PMID:23434795, PMID:27472835, PMID:31476115, PMID:31626304 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Csf3r colony stimulating factor 3 receptor decreases expression ISO Ozone results in decreased expression of CSF3R mRNA CTD PMID:17095637 NCBI chr 5:144,031,353...144,051,966
Ensembl chr 5:144,031,402...144,051,600
JBrowse link
G Csn3 casein kappa decreases expression ISO Ozone results in decreased expression of CSN3 mRNA CTD PMID:19555225 NCBI chr14:21,803,738...21,810,291
Ensembl chr14:21,803,735...21,810,314
JBrowse link
G Csnk1g1 casein kinase 1, gamma 1 multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of CSNK1G1 mRNA CTD PMID:18636392 NCBI chr 8:71,533,372...71,688,483
Ensembl chr 8:71,547,468...71,679,666
JBrowse link
G Cspp1 centrosome and spindle pole associated protein 1 increases expression ISO Ozone results in increased expression of CSPP1 mRNA CTD PMID:28652203 NCBI chr 5:8,761,293...8,876,205
Ensembl chr 5:8,761,293...8,864,578
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 decreases expression
multiple interactions
ISO
EXP
Ozone results in decreased expression of CSRP3 mRNA
[Ozone co-treated with Chlorine] results in increased expression of CSRP3 mRNA
CTD PMID:12763052, PMID:18636392 NCBI chr 1:104,147,205...104,166,389
Ensembl chr 1:104,147,206...104,166,367
JBrowse link
G Ctdsp1 CTD small phosphatase 1 decreases expression ISO Ozone results in decreased expression of CTDSP1 mRNA CTD PMID:28652203 NCBI chr 9:81,672,613...81,677,979
Ensembl chr 9:81,672,758...81,677,979
JBrowse link
G Ctnna2 catenin alpha 2 decreases expression ISO Ozone results in decreased expression of CTNNA2 mRNA CTD PMID:12763052 NCBI chr 4:107,880,611...109,042,724
Ensembl chr 4:107,881,826...108,008,484
JBrowse link
G Ctnnal1 catenin alpha-like 1 increases expression ISO Ozone results in increased expression of CTNNAL1 mRNA CTD PMID:28652203 NCBI chr 5:73,561,249...73,621,070
Ensembl chr 5:73,561,450...73,621,070
JBrowse link
G Ctps1 CTP synthase 1 multiple interactions
increases expression
ISO TTPA protein affects the reaction [Ozone results in increased expression of CTPS mRNA] CTD PMID:19555225, PMID:25658374 NCBI chr 5:139,475,934...139,505,065
Ensembl chr 5:139,475,934...139,505,065
JBrowse link
G Ctsb cathepsin B multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of CTSB mRNA CTD PMID:18636392 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctse cathepsin E increases expression
multiple interactions
ISO Ozone results in increased expression of CTSE mRNA
IL10 gene mutant form promotes the reaction [Ozone results in increased expression of CTSE mRNA]
CTD PMID:20826374 NCBI chr13:48,426,833...48,449,493
Ensembl chr13:48,426,820...48,449,490
JBrowse link
G Ctsh cathepsin H increases expression ISO Ozone results in increased expression of CTSH mRNA CTD PMID:12763052 NCBI chr 8:97,439,155...97,458,293
Ensembl chr 8:97,439,161...97,458,287
JBrowse link
G Ctsk cathepsin K multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CTSK mRNA; TTPA protein affects the reaction [Ozone results in increased expression of CTSK mRNA] CTD PMID:19555225, PMID:25658374 NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446
JBrowse link
G Ctsl cathepsin L multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of CTSL mRNA CTD PMID:18636392 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cuta cutA divalent cation tolerance homolog decreases expression ISO Ozone results in decreased expression of CUTA mRNA CTD PMID:12763052 NCBI chr20:5,532,024...5,533,640
Ensembl chr20:5,532,024...5,533,620
JBrowse link
G Cwh43 cell wall biogenesis 43 C-terminal homolog increases expression ISO Ozone results in increased expression of CWH43 mRNA CTD PMID:31626304 NCBI chr14:37,315,479...37,361,728
Ensembl chr14:37,315,406...37,361,798
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 decreases expression
increases expression
multiple interactions
EXP
ISO
Ozone results in decreased expression of CX3CL1 mRNA
Ozone results in increased expression of CX3CL1 mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of CX3CL1 mRNA
CTD PMID:16716893, PMID:31476115 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions
increases expression
EXP
ISO
Dexamethasone inhibits the reaction [Ozone results in increased expression of CXCL1 mRNA]; Metyrapone inhibits the reaction [Ozone results in increased expression of CXCL1 protein]
[Aripiprazole co-treated with Ozone] results in increased expression of CXCL1 mRNA
Ozone results in increased expression of CXCL1 mRNA; Ozone results in increased expression of CXCL1 protein; Ozone results in increased expression of GRO1 mRNA
CTD PMID:8603703, PMID:9230754, PMID:16716893, PMID:26667333, PMID:27037194, PMID:31476115 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions
increases secretion
increases response to substance
increases expression
ISO
EXP
[LEP gene mutant form results in increased susceptibility to Ozone] which results in increased expression of CXCL10 protein; [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CXCL10 mRNA; IL1R1 gene mutant form inhibits the reaction [Ozone results in increased expression of CXCL10 protein]
Ozone results in increased secretion of CXCL10 protein
[Ozone co-treated with Chlorine] results in increased expression of CXCL10 mRNA
CXCL10 protein results in increased susceptibility to Ozone
Ozone results in increased expression of CXCL10 mRNA; Ozone results in increased expression of CXCL10 protein
CTD PMID:11777981, PMID:17575079, PMID:18636392, PMID:25658374, PMID:26342085, PMID:27472835, PMID:30848106, PMID:31626304 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 increases expression ISO Ozone results in increased expression of CXCL11 mRNA CTD PMID:27240593 NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 decreases expression ISO Ozone results in decreased expression of CXCL14 mRNA CTD PMID:12763052 NCBI chr17:9,109,731...9,117,754
Ensembl chr17:9,109,731...9,117,750
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression
ISO
EXP
[Acetaminophen co-treated with Ozone] results in increased expression of CXCL2 mRNA; [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CXCL2 mRNA; CPE gene mutant form promotes the reaction [Ozone results in increased expression of CXCL2 protein]; CR1L protein affects the reaction [Ozone results in increased expression of CXCL2 protein]; Dexamethasone inhibits the reaction [Ozone results in increased expression of CXCL2 protein]; Endotoxins promotes the reaction [Ozone results in increased expression of CXCL2 mRNA]; ERCC6 gene mutant form promotes the reaction [Ozone results in increased expression of CXCL2 protein]; IL10 gene mutant form promotes the reaction [Ozone results in increased expression of CXCL2 mRNA]; IL1R1 gene mutant form affects the reaction [Ozone results in increased expression of CXCL2 protein]; IL1RN protein inhibits the reaction [Ozone results in increased expression of CXCL2 protein]; LEPR gene mutant form promotes the reaction [Ozone results in increased expression of CXCL2 protein]; MMP9 gene mutant form promotes the reaction [Ozone results in increased expression of CXCL2 mRNA]; MMP9 gene mutant form promotes the reaction [Ozone results in increased expression of CXCL2 protein]; NOTCH4 gene mutant form promotes the reaction [Ozone results in increased expression of CXCL2 mRNA]; SCGB1A1 protein affects the reaction [Ozone results in increased expression of CXCL2 mRNA]; SFTPA1 gene mutant form inhibits the reaction [Ozone results in increased expression of CXCL2 mRNA]
[Aripiprazole co-treated with Ozone] results in increased expression of CXCL2 mRNA
Ozone results in increased expression of CXCL2 mRNA; Ozone results in increased expression of CXCL2 protein
[Ozone co-treated with Nitrogen Dioxide] results in increased expression of CXCL2 mRNA; Dexamethasone inhibits the reaction [Ozone results in increased expression of CXCL2 mRNA]; IL1B protein affects the reaction [Ozone results in increased expression of CXCL2 mRNA]; TNF protein affects the reaction [Ozone results in increased expression of CXCL2 mRNA]
CTD PMID:7737418, PMID:8480341, PMID:9439717, PMID:9458799, PMID:10027076, PMID:10027081, PMID:10706030, PMID:10715624, PMID:10986008, PMID:11498801, PMID:11777981, PMID:12217210, PMID:12794034, PMID:14701711, PMID:14754758, PMID:15361358, PMID:15371095, PMID:15516495, PMID:16002559, PMID:16330353, PMID:16373670, PMID:17095637, PMID:17307210, PMID:17460151, PMID:17575079, PMID:18007984, PMID:19555225, PMID:20123758, PMID:20826374, PMID:25658374, PMID:26342085, PMID:27472835, PMID:28623178, PMID:30848106, PMID:31476115 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression
increases secretion
multiple interactions
increases expression
ISO
EXP
Ozone results in decreased expression of CXCL1 mRNA
Ozone results in increased secretion of CXCL1 protein
[Aripiprazole co-treated with Ozone] results in increased expression of CXCL1 mRNA
Ozone results in increased expression of CXCL1 mRNA
[Acetaminophen co-treated with Ozone] results in increased expression of CXCL1 mRNA; [CPE affects the susceptibility to Ozone] which affects the expression of CXCL1 protein; [LEP gene mutant form results in increased susceptibility to Ozone] which results in increased expression of CXCL1 protein; [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CXCL3 mRNA; [NOTCH4 gene mutant form affects the susceptibility to Ozone] which affects the expression of CXCL3 mRNA; [Ozone co-treated with Acetaminophen] results in increased expression of CXCL1 protein; [Ozone co-treated with Lipopolysaccharides] results in increased expression of CXCL1 protein; CPE gene mutant form promotes the reaction [Ozone results in increased expression of CXCL1 protein]; CR1L protein affects the reaction [Ozone results in increased expression of CXCL1 protein]; IL13 protein affects the reaction [Ozone results in increased expression of CXCL1 mRNA]; IL1RL1 protein affects the reaction [[LEP gene mutant form results in increased susceptibility to Ozone] which results in increased expression of CXCL1 protein]; IL1RN protein inhibits the reaction [Ozone results in increased expression of CXCL1 protein]; LEP gene mutant form promotes the reaction [Ozone results in increased expression of CXCL1 protein]; LEPR gene mutant form promotes the reaction [Ozone results in increased expression of CXCL1 protein]; MMP9 gene mutant form promotes the reaction [Ozone results in increased expression of CXCL1 mRNA]; MMP9 gene mutant form promotes the reaction [Ozone results in increased expression of CXCL1 protein]; MYD88 gene mutant form inhibits the reaction [Ozone results in increased expression of CXCL1 mRNA]; NGF protein promotes the reaction [Ozone results in increased expression of CXCL1 protein]; NQO1 protein promotes the reaction [Ozone results in increased expression of CXCL1 protein]; TLR2 gene mutant form inhibits the reaction [Ozone results in increased expression of CXCL1 mRNA]; TLR4 gene mutant form inhibits the reaction [Ozone results in increased expression of CXCL1 mRNA]
Ozone results in increased expression of CXCL1 mRNA; Ozone results in increased expression of CXCL1 protein; Ozone results in increased expression of CXCL3 mRNA
CTD PMID:11463606, PMID:11777981, PMID:12794034, PMID:14701711, PMID:14754758, PMID:15361358, PMID:15371095, PMID:15516495, PMID:16002559, PMID:16373670, PMID:16716893, PMID:17095637, PMID:17460151, PMID:17575079, PMID:17626835, PMID:18007984, PMID:18417511, PMID:18929643, PMID:19059883, PMID:20123758, PMID:21543283, PMID:23434795, PMID:25658374, PMID:26342085, PMID:26667333, PMID:27472835, PMID:28533327, PMID:29471542, PMID:30848106, PMID:31476115, PMID:31626304 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 increases expression ISO Ozone results in increased expression of CXCL6 mRNA CTD PMID:31476115 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 multiple interactions ISO [LEP gene mutant form results in increased susceptibility to Ozone] which results in increased expression of CXCL9 protein CTD PMID:27472835 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 multiple interactions ISO Ozone promotes the reaction [CXCR2 protein affects the susceptibility to Methacholine Chloride] CTD PMID:15361358 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 increases expression ISO Ozone results in increased expression of CXCR3 mRNA CTD PMID:31626304 NCBI chr  X:71,614,346...71,616,997
Ensembl chr  X:71,614,346...71,616,997
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions
decreases expression
EXP
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CXCR4 mRNA
Ozone results in decreased expression of CXCR4 mRNA
CTD PMID:18636392, PMID:26342085 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 increases expression
multiple interactions
ISO Ozone results in increased expression of CXCR5 mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of CXCR5 mRNA
CTD PMID:31476115 NCBI chr 8:48,835,688...48,852,032
Ensembl chr 8:48,836,957...48,850,671
JBrowse link
G Cxcr6 C-X-C motif chemokine receptor 6 multiple interactions
increases expression
ISO [Aripiprazole co-treated with Ozone] results in increased expression of CXCR6 mRNA
Ozone results in increased expression of CXCR6 mRNA
CTD PMID:31476115 NCBI chr 8:132,869,712...132,870,766
Ensembl chr 8:132,869,712...132,870,767
JBrowse link
G Cybb cytochrome b-245 beta chain increases expression
multiple interactions
ISO Ozone results in increased expression of CYBB mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of CYBB mRNA
CTD PMID:31476115 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cyld CYLD lysine 63 deubiquitinase multiple interactions
increases expression
ISO [Aripiprazole co-treated with Ozone] results in increased expression of CYLD mRNA
Ozone results in increased expression of CYLD mRNA
CTD PMID:31476115 NCBI chr19:19,264,984...19,323,817
Ensembl chr19:19,265,164...19,315,357
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of CYP11A1 mRNA CTD PMID:18636392 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO Ozone results in decreased expression of CYP17A1 mRNA CTD PMID:16183385 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of CYP19A1 mRNA CTD PMID:18636392 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases expression
increases expression
ISO
EXP
AHR protein affects the reaction [Ozone results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [Ozone results in increased expression of CYP1A1 protein]
Ozone results in decreased expression of CYP1A1 mRNA
[Ozone co-treated with Particulate Matter] results in increased expression of CYP1A1 mRNA
Ozone results in increased expression of CYP1A1 mRNA; Ozone results in increased expression of CYP1A1 protein
CTD PMID:19536146, PMID:23805001, PMID:31626304 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
decreases expression
increases expression
ISO AHR protein affects the reaction [Ozone results in increased expression of CYP1A2 mRNA]; AHR protein affects the reaction [Ozone results in increased expression of CYP1A2 protein]
Ozone results in decreased expression of CYP1A2 mRNA
Ozone results in increased expression of CYP1A2 mRNA; Ozone results in increased expression of CYP1A2 protein
CTD PMID:16183385, PMID:19536146 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
increases expression
ISO AHR protein affects the reaction [Ozone results in increased expression of CYP1B1 mRNA]; AHR protein affects the reaction [Ozone results in increased expression of CYP1B1 protein]
Ozone results in increased expression of CYP1B1 mRNA; Ozone results in increased expression of CYP1B1 protein
CTD PMID:19536146 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 decreases expression ISO Ozone results in decreased expression of CYP2A5 mRNA CTD PMID:12763052, PMID:16183385 NCBI chr 1:83,653,248...83,662,118
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression ISO Ozone results in increased expression of CYP2B6 mRNA CTD PMID:24336422 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 decreases expression EXP Ozone results in decreased expression of CYP2B15 mRNA CTD PMID:16716893 NCBI chr 1:251,325,923...251,338,404
Ensembl chr 1:251,325,923...251,338,358
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of CYP2C mRNA CTD PMID:18636392 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases expression ISO Ozone results in decreased expression of CYP2C29 mRNA CTD PMID:16183385 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 decreases expression ISO Ozone results in decreased expression of CYP2D10 mRNA CTD PMID:16183385 NCBI chr 7:123,625,641...123,630,045
Ensembl chr 7:123,625,590...123,638,765
JBrowse link
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 decreases expression EXP Ozone results in decreased expression of CYP2D3 mRNA CTD PMID:26667333 NCBI chr 7:123,634,400...123,638,757
Ensembl chr 7:123,625,590...123,638,765
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression ISO Ozone results in decreased expression of CYP2E1 mRNA CTD PMID:12763052 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 decreases expression ISO Ozone results in decreased expression of CYP2F2 mRNA CTD PMID:9700096, PMID:12763052 NCBI chr 1:83,933,974...83,947,804
Ensembl chr 1:83,933,942...83,947,821
JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 decreases expression ISO Ozone results in decreased expression of CYP2S1 mRNA CTD PMID:12763052 NCBI chr 1:82,595,211...82,610,350
Ensembl chr 1:82,595,211...82,610,350
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 decreases expression ISO Ozone results in decreased expression of CYP4A12B mRNA CTD PMID:31626304 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of CYP4A3 mRNA CTD PMID:18636392 NCBI chr 5:134,468,666...134,484,851
Ensembl chr 5:134,469,270...134,484,839
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 decreases expression ISO Ozone results in decreased expression of CYP4B1 mRNA CTD PMID:16183385 NCBI chr 5:134,508,728...134,526,103
Ensembl chr 5:134,508,730...134,526,089
JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of CYP4F4 mRNA CTD PMID:18636392 NCBI chr 7:14,891,062...14,907,250
Ensembl chr 7:14,891,001...14,907,305
JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression ISO Ozone results in increased expression of CYP51 mRNA CTD PMID:12763052 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 decreases expression
multiple interactions
increases expression
ISO Ozone results in decreased expression of CYP7B1 mRNA
[NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CYP7B1 mRNA
Ozone results in increased expression of CYP7B1 mRNA
CTD PMID:16183385, PMID:21543283, PMID:25658374 NCBI chr 2:102,701,903...102,871,257
Ensembl chr 2:102,701,903...102,871,257
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 decreases expression ISO Ozone results in decreased expression of CYP8B1 mRNA CTD PMID:16183385 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G Cytl1 cytokine like 1 increases expression EXP Ozone results in increased expression of CYTL1 mRNA CTD PMID:28623178 NCBI chr14:77,805,137...77,810,147
Ensembl chr14:77,805,130...77,810,147
JBrowse link
G Dact2 dishevelled-binding antagonist of beta-catenin 2 decreases expression ISO Ozone results in decreased expression of DACT2 mRNA CTD PMID:31626304 NCBI chr 1:56,159,435...56,169,443
Ensembl chr 1:56,159,426...56,168,351
JBrowse link
G Dag1 dystroglycan 1 decreases expression EXP Ozone results in decreased expression of DAG1 mRNA CTD PMID:16716893 NCBI chr 8:116,980,501...116,993,182
Ensembl chr 8:116,980,497...116,993,193
JBrowse link
G Dbf4 DBF4 zinc finger decreases expression ISO Ozone results in decreased expression of DBF4 mRNA CTD PMID:24336422 NCBI chr 4:22,898,527...22,914,091
Ensembl chr 4:22,898,527...22,914,177
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor decreases expression ISO Ozone results in decreased expression of DBP mRNA CTD PMID:12763052 NCBI chr 1:101,687,896...101,692,845
Ensembl chr 1:101,687,855...101,692,846
JBrowse link
G Dck deoxycytidine kinase decreases expression ISO Ozone results in decreased expression of DCK mRNA CTD PMID:24336422 NCBI chr14:20,935,442...20,952,939
Ensembl chr14:20,935,369...20,953,095
JBrowse link
G Dcn decorin decreases expression ISO Ozone results in decreased expression of DCN mRNA CTD PMID:12763052 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Dcx doublecortin decreases expression EXP Ozone results in decreased expression of DCX protein CTD PMID:19833740 NCBI chr  X:115,098,675...115,175,515
Ensembl chr  X:115,098,675...115,175,299
JBrowse link
G Ddb2 damage specific DNA binding protein 2 increases expression ISO Ozone results in increased expression of DDB2 mRNA CTD PMID:27206323 NCBI chr 3:80,030,437...80,052,984
Ensembl chr 3:80,030,437...80,052,953
JBrowse link
G Ddc dopa decarboxylase multiple interactions EXP
ISO
[Ozone co-treated with Chlorine] affects the expression of DDC mRNA
[NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in decreased expression of DDC mRNA; [NOTCH4 gene mutant form affects the susceptibility to Ozone] which affects the expression of DDC mRNA
CTD PMID:18636392, PMID:25658374 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of DDIT3 mRNA CTD PMID:18636392 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO Ozone results in increased expression of DDIT4 mRNA CTD PMID:17460151 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Ddx58 DEXD/H-box helicase 58 increases expression
multiple interactions
ISO Ozone results in increased expression of DDX58 mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of DDX58 mRNA
CTD PMID:31476115 NCBI chr 5:56,486,584...56,536,898
Ensembl chr 5:56,500,734...56,536,772
JBrowse link
G Depdc1 DEP domain containing 1 affects expression
multiple interactions
ISO Ozone affects the expression of DEPDC1A mRNA
[NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of DEPDC1A mRNA; [NOTCH4 gene mutant form affects the susceptibility to Ozone] which affects the expression of DEPDC1A mRNA
CTD PMID:25658374 NCBI chr 2:264,704,738...264,738,265
Ensembl chr 2:264,704,769...264,738,257
JBrowse link
G Depdc1b DEP domain containing 1B decreases expression ISO Ozone results in decreased expression of DEPDC1B mRNA CTD PMID:24336422 NCBI chr 2:39,980,796...40,069,982
Ensembl chr 2:40,000,313...40,069,975
JBrowse link
G Deptor DEP domain containing MTOR-interacting protein decreases expression ISO Ozone results in decreased expression of DEPTOR mRNA CTD PMID:28652203 NCBI chr 7:94,795,161...95,000,750
Ensembl chr 7:94,795,214...94,995,809
JBrowse link
G Dgkk diacylglycerol kinase kappa increases expression ISO Ozone results in increased expression of DGKK mRNA CTD PMID:27206323 NCBI chr  X:16,441,318...16,526,046
Ensembl chr  X:16,442,899...16,537,888
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression EXP Ozone results in decreased expression of DHCR7 mRNA CTD PMID:16716893 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904
JBrowse link
G Dio3 iodothyronine deiodinase 3 increases expression ISO Ozone results in increased expression of DIO3 mRNA CTD PMID:31626304 NCBI chr 6:134,627,278...134,629,139
Ensembl chr 6:134,627,278...134,629,138
JBrowse link
G Disp1 dispatched RND transporter family member 1 decreases expression EXP Ozone results in decreased expression of DISP1 mRNA CTD PMID:28623178 NCBI chr13:101,451,932...101,597,570
Ensembl chr13:101,451,932...101,597,570
JBrowse link
G Dld dihydrolipoamide dehydrogenase decreases expression ISO Ozone results in decreased expression of DLD mRNA CTD PMID:16183385 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694
JBrowse link
G Dlgap5 DLG associated protein 5 decreases expression
multiple interactions
ISO Ozone results in decreased expression of DLGAP5 mRNA
[NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of DLGAP5 mRNA
CTD PMID:24336422, PMID:25658374 NCBI chr15:24,167,484...24,199,417
Ensembl chr15:24,167,486...24,199,341
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase increases expression EXP Ozone results in increased expression of DLST mRNA CTD PMID:25838073 NCBI chr 6:108,936,534...108,961,322
Ensembl chr 6:108,936,664...108,959,803
JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 decreases expression ISO Ozone results in decreased expression of DMBT1 mRNA CTD PMID:12763052 NCBI chr 1:201,620,642...201,689,905
NCBI chr 1:203,149,414...203,228,705
JBrowse link
G Dnaaf4 dynein axonemal assembly factor 4 decreases expression ISO Ozone results in decreased expression of DYX1C1 mRNA CTD PMID:31626304 NCBI chr 8:79,637,678...79,651,892
Ensembl chr 8:79,638,696...79,651,884
JBrowse link
G Dnaaf6 dynein axonemal assembly factor 6 decreases expression ISO Ozone results in decreased expression of DNAAF6B mRNA CTD PMID:31626304 NCBI chr  X:111,389,557...111,439,399
Ensembl chr  X:111,396,995...111,439,376
JBrowse link
G Dnah2 dynein, axonemal, heavy chain 2 decreases expression ISO Ozone results in decreased expression of DNAH2 mRNA CTD PMID:31626304 NCBI chr10:56,029,022...56,154,602
Ensembl chr10:56,029,029...56,154,548
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 increases expression ISO Ozone results in increased expression of DNAJA1 mRNA CTD PMID:21543283 NCBI chr 5:57,028,467...57,039,378
Ensembl chr 5:57,028,467...57,039,378
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Ozone results in increased expression of DNAJB4 mRNA CTD PMID:21543283 NCBI chr 2:257,394,692...257,425,344
Ensembl chr 2:257,394,818...257,425,242
JBrowse link
G Dnali1 dynein, axonemal, light intermediate chain 1 decreases expression ISO Ozone results in decreased expression of DNALI1 mRNA CTD PMID:17095637 NCBI chr 5:143,053,365...143,062,203
Ensembl chr 5:143,053,367...143,062,226
JBrowse link
G Dnmt1 DNA methyltransferase 1 affects response to substance ISO DNMT1 gene polymorphism affects the susceptibility to Ozone CTD PMID:27219456 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression EXP Ozone results in decreased expression of DNMT3A mRNA CTD PMID:29947284 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta affects response to substance
decreases expression
ISO
EXP
DNMT3B gene polymorphism affects the susceptibility to Ozone
Ozone results in decreased expression of DNMT3B mRNA
CTD PMID:27219456, PMID:29947284 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Dntt DNA nucleotidylexotransferase increases expression ISO Ozone results in increased expression of DNTT mRNA CTD PMID:12763052 NCBI chr 1:260,289,626...260,321,174
Ensembl chr 1:260,289,589...260,321,320
JBrowse link
G Doc2b double C2 domain beta increases expression
multiple interactions
ISO Ozone results in increased expression of DOC2B mRNA
pyrazolanthrone inhibits the reaction [Ozone results in increased expression of DOC2B mRNA]
CTD PMID:17460151 NCBI chr10:63,921,255...63,952,944
Ensembl chr10:63,928,064...63,952,726
JBrowse link
G Dpep1 dipeptidase 1 decreases expression EXP Ozone results in decreased expression of DPEP1 mRNA CTD PMID:16330353 NCBI chr19:55,973,447...55,998,830
Ensembl chr19:55,982,740...55,998,208
JBrowse link
G Dpp4 dipeptidylpeptidase 4 multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of DPP4 mRNA CTD PMID:18636392 NCBI chr 3:48,291,055...48,372,672
Ensembl chr 3:48,291,055...48,372,672
JBrowse link
G Dpp6 dipeptidyl peptidase like 6 multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of DPP6 mRNA CTD PMID:18636392 NCBI chr 4:4,021,021...4,943,675
Ensembl chr 4:4,021,008...4,473,307
JBrowse link
G Dpt dermatopontin decreases expression ISO Ozone results in decreased expression of DPT mRNA CTD PMID:12763052 NCBI chr13:83,073,307...83,102,404
Ensembl chr13:83,073,544...83,102,401
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of DRD1 mRNA CTD PMID:18636392 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drp2 dystrophin related protein 2 decreases expression EXP Ozone results in decreased expression of DRP2 mRNA CTD PMID:28623178 NCBI chr  X:105,239,623...105,290,233
Ensembl chr  X:105,239,620...105,289,808
JBrowse link
G Dscc1 DNA replication and sister chromatid cohesion 1 multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of DSCC1 mRNA CTD PMID:25658374 NCBI chr 7:94,759,076...94,774,787
Ensembl chr 7:94,758,800...94,774,569
JBrowse link
G Dsel dermatan sulfate epimerase-like increases expression ISO Ozone results in increased expression of DSEL mRNA CTD PMID:28652203 NCBI chr13:1,942,384...1,948,563
Ensembl chr13:1,942,499...1,946,508
JBrowse link
G Dthd1 death domain containing 1 decreases expression ISO Ozone results in decreased expression of DTHD1 mRNA CTD PMID:31626304 NCBI chr14:48,612,893...48,677,023
Ensembl chr14:48,629,983...48,676,829
JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of DTL mRNA CTD PMID:25658374 NCBI chr13:110,219,276...110,257,345
Ensembl chr13:110,220,283...110,257,367
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Ozone results in increased expression of DUSP1 mRNA CTD PMID:27206323 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression EXP Ozone results in increased expression of DUSP10 mRNA CTD PMID:28623178 NCBI chr13:104,284,660...104,321,455
Ensembl chr13:104,284,660...104,321,455
JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression
multiple interactions
ISO Ozone results in increased expression of DUSP4 mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of DUSP4 mRNA
CTD PMID:31476115 NCBI chr16:61,080,767...61,090,973
Ensembl chr16:61,078,175...61,091,169
JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression EXP Ozone results in increased expression of DUSP5 mRNA CTD PMID:16716893 NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595
JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression
multiple interactions
ISO Ozone results in increased expression of DUSP6 mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of DUSP6 mRNA
CTD PMID:31476115 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Dynll1 dynein light chain LC8-type 1 decreases expression EXP Ozone results in decreased expression of DYNLL1 mRNA; Ozone results in decreased expression of PIN mRNA CTD PMID:26667333, PMID:28623178 NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572
JBrowse link
G E2f7 E2F transcription factor 7 multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of E2F7 mRNA CTD PMID:25658374 NCBI chr 7:53,275,659...53,318,261
Ensembl chr 7:53,275,676...53,316,481
JBrowse link
G Ebi3 Epstein-Barr virus induced 3 multiple interactions
increases expression
ISO Aripiprazole promotes the reaction [Ozone results in increased expression of EBI3 mRNA] CTD PMID:31476115 NCBI chr 9:11,110,874...11,114,843
Ensembl chr 9:11,110,874...11,114,843
JBrowse link
G Ece1 endothelin converting enzyme 1 increases expression EXP Ozone results in increased expression of ECE1 mRNA CTD PMID:16081523, PMID:17662977 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671
JBrowse link
G Eci2 enoyl-CoA delta isomerase 2 increases expression ISO Ozone results in increased expression of ECI2 mRNA CTD PMID:17095637 NCBI chr17:30,556,926...30,573,324
Ensembl chr17:30,556,884...30,639,040
JBrowse link
G Ecm2 extracellular matrix protein 2 multiple interactions ISO [NOTCH4 gene mutant form affects the susceptibility to Ozone] which affects the expression of ECM2 mRNA CTD PMID:25658374 NCBI chr17:15,533,760...15,566,403
Ensembl chr17:15,533,972...15,566,332
JBrowse link
G Ect2 epithelial cell transforming 2 multiple interactions
increases expression
ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of ECT2 mRNA; TTPA protein affects the reaction [Ozone results in increased expression of ECT2 mRNA] CTD PMID:12763052, PMID:19555225, PMID:25658374 NCBI chr 2:112,769,385...112,831,476
Ensembl chr 2:112,769,385...112,831,476
JBrowse link
G Edn1 endothelin 1 multiple interactions
increases expression
EXP
ISO
[Particulate Matter co-treated with Ozone] results in increased expression of EDN1 mRNA
Ozone results in increased expression of EDN1 mRNA
Ozone results in increased expression of EDN1 mRNA; Ozone results in increased expression of EDN1 protein
CTD PMID:16081523, PMID:16716893, PMID:16741034, PMID:17662977, PMID:20980218, PMID:27206323 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Edn3 endothelin 3 decreases expression
increases expression
EXP Ozone results in decreased expression of EDN3 mRNA
Ozone results in increased expression of EDN3 mRNA; Ozone results in increased expression of EDN3 protein
CTD PMID:16741034, PMID:17662977 NCBI chr 3:172,856,730...172,879,276
Ensembl chr 3:172,856,733...172,880,450
JBrowse link
G Ednra endothelin receptor type A decreases expression
increases expression
EXP Ozone results in decreased expression of EDNRA mRNA
Ozone results in increased expression of EDNRA mRNA
CTD PMID:16081523, PMID:20980218 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Ednrb endothelin receptor type B multiple interactions
increases expression
EXP
ISO
[Ozone co-treated with Vehicle Emissions] results in increased expression of EDNRB mRNA
Ozone results in increased expression of EDNRB mRNA
CTD PMID:16081523, PMID:20980218, PMID:31626304 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of EEF2 mRNA CTD PMID:18636392 NCBI chr 7:11,401,501...11,406,771
Ensembl chr 7:11,401,501...11,406,771
JBrowse link
G Efnb2 ephrin B2 decreases expression ISO Ozone results in decreased expression of EFNB2 mRNA CTD PMID:12763052 NCBI chr16:86,631,151...86,672,050
Ensembl chr16:86,631,064...86,675,049
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases phosphorylation
ISO AG 1879 inhibits the reaction [Ozone results in increased phosphorylation of EGFR protein]; AHR protein affects the reaction [Ozone results in increased phosphorylation of EGFR protein]; Protein Kinase Inhibitors inhibits the reaction [Ozone results in increased phosphorylation of EGFR protein]
4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Ozone results in increased phosphorylation of EGFR protein]
CTD PMID:19536146, PMID:25303742, PMID:26464147 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 increases expression ISO Ozone results in increased expression of EGLN3 mRNA CTD PMID:31626304 NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795
JBrowse link
G Egr1 early growth response 1 multiple interactions
increases expression
EXP [Ozone co-treated with Chlorine] results in increased expression of EGR1 mRNA
Ozone results in increased expression of EGR1 mRNA
CTD PMID:16716893, PMID:18636392, PMID:28623178 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Egr2 early growth response 2 multiple interactions ISO TTPA protein affects the reaction [Ozone results in increased expression of EGR2 mRNA] CTD PMID:19555225 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 decreases expression ISO Ozone results in decreased expression of EHMT2 mRNA CTD PMID:17460151 NCBI chr20:4,576,033...4,592,980
Ensembl chr20:4,576,057...4,592,980
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of EIF2S1 mRNA CTD PMID:18636392 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 decreases expression ISO Ozone results in decreased expression of EIF4A2 mRNA CTD PMID:17095637 NCBI chr11:81,373,047...81,379,680
Ensembl chr11:81,373,048...81,379,871
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of EIF5 mRNA CTD PMID:18636392 NCBI chr 6:136,002,983...136,011,409
Ensembl chr 6:136,004,214...136,011,406
JBrowse link
G Elane elastase, neutrophil expressed multiple interactions
increases expression
ISO [Aripiprazole co-treated with Ozone] results in increased expression of ELANE mRNA
Ozone results in increased expression of ELANE mRNA
CTD PMID:31476115 NCBI chr 7:12,638,320...12,640,168
Ensembl chr 7:12,638,322...12,640,232
JBrowse link
G Eln elastin increases expression EXP Ozone results in increased expression of ELN mRNA CTD PMID:7840908 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863
JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 decreases expression ISO Ozone results in decreased expression of ELOVL3 mRNA CTD PMID:16183385 NCBI chr 1:265,883,353...265,887,181
Ensembl chr 1:265,883,355...265,887,226
JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 decreases expression EXP Ozone results in decreased expression of ELOVL7 mRNA CTD PMID:31397875 NCBI chr 2:40,373,211...40,386,643
Ensembl chr 2:40,373,211...40,386,669
JBrowse link
G Emcn endomucin decreases expression EXP Ozone results in decreased expression of EMCN mRNA CTD PMID:31397875 NCBI chr 2:242,634,319...242,715,489
Ensembl chr 2:242,634,399...242,714,182
JBrowse link
G Eno1 enolase 1 increases expression EXP Ozone results in increased expression of ENO1 mRNA CTD PMID:25838073 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Eno3 enolase 3 decreases expression ISO Ozone results in decreased expression of ENO3 mRNA CTD PMID:12763052 NCBI chr10:57,278,271...57,283,661
Ensembl chr10:57,278,307...57,283,653
JBrowse link
G Epha3 Eph receptor A3 decreases expression EXP Ozone results in decreased expression of EPHA3 mRNA CTD PMID:16330353 NCBI chr11:421,253...783,037
Ensembl chr11:421,135...782,954
JBrowse link
G Ephx1 epoxide hydrolase 1 decreases expression ISO Ozone results in decreased expression of EPHX1 mRNA CTD PMID:12763052 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Ephx2 epoxide hydrolase 2 increases expression ISO Ozone results in increased expression of EPHX2 mRNA CTD PMID:27206323 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Epo erythropoietin increases expression ISO Ozone results in increased expression of EPO mRNA CTD PMID:27206323 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit increases expression ISO Ozone results in increased expression of ERCC4 mRNA CTD PMID:28652203 NCBI chr10:2,010,140...2,037,953
Ensembl chr10:2,010,648...2,037,891
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor multiple interactions ISO ERCC6 gene mutant form promotes the reaction [Ozone results in increased expression of CXCL2 protein]; ERCC6 gene mutant form promotes the reaction [Ozone results in increased expression of TNF protein] CTD PMID:17095637 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610
JBrowse link
G Ereg epiregulin increases expression
multiple interactions
EXP
ISO
Ozone results in increased expression of EREG mRNA
[NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of EREG mRNA; [NOTCH4 gene mutant form affects the susceptibility to Ozone] which affects the expression of EREG mRNA
CTD PMID:16716893, PMID:25658374 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 multiple interactions
increases expression
ISO
EXP
TTPA protein affects the reaction [Ozone results in increased expression of ERRFI1 mRNA] CTD PMID:19555225, PMID:28623178 NCBI chr 5:167,951,564...167,966,011
Ensembl chr 5:167,952,728...167,966,009
JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 decreases expression
multiple interactions
ISO Ozone results in decreased expression of ESCO2 mRNA
[NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of ESCO2 mRNA
CTD PMID:24336422, PMID:25658374 NCBI chr15:42,500,929...42,519,019
Ensembl chr15:42,500,929...42,518,855
JBrowse link
G Esd esterase D increases expression ISO Ozone results in increased expression of ESD mRNA CTD PMID:17095637 NCBI chr15:56,756,848...56,776,348
Ensembl chr15:56,756,661...56,776,348
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO [[Ozone results in increased oxidation of Particulate Matter] which results in increased chemical synthesis of Aerosols] which results in decreased expression of ESR1 mRNA; [[Ozone results in increased oxidation of Vehicle Emissions] which results in increased chemical synthesis of Aerosols] which results in decreased expression of ESR1 mRNA CTD PMID:25361045 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esrp2 epithelial splicing regulatory protein 2 increases expression ISO Ozone results in increased expression of ESRP2 mRNA CTD PMID:31626304 NCBI chr19:38,113,412...38,120,578
Ensembl chr19:38,113,412...38,120,578
JBrowse link
G Esrra estrogen related receptor, alpha increases expression EXP Ozone results in increased expression of ESRRA mRNA CTD PMID:25838073 NCBI chr 1:222,168,729...222,178,842
Ensembl chr 1:222,168,730...222,178,725
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor multiple interactions
increases expression
ISO [Aripiprazole co-treated with Ozone] results in increased expression of ETS1 mRNA
Ozone results in increased expression of ETS1 mRNA
CTD PMID:31476115 NCBI chr 8:33,756,634...33,879,625
Ensembl chr 8:33,816,386...33,879,625
JBrowse link
G Evl Enah/Vasp-like decreases expression ISO Ozone results in decreased expression of EVL mRNA CTD PMID:12763052 NCBI chr 6:132,470,283...132,590,242
Ensembl chr 6:132,510,757...132,590,241
JBrowse link
G Exoc5 exocyst complex component 5 increases expression ISO Ozone results in increased expression of EXOC5 mRNA CTD PMID:28652203 NCBI chr15:25,888,757...25,933,302
Ensembl chr15:25,887,070...25,933,268
JBrowse link
G F13a1 coagulation factor XIII A1 chain increases expression ISO Ozone results in increased expression of F13A1 mRNA CTD PMID:31626304 NCBI chr17:28,504,650...28,680,015
Ensembl chr17:28,504,623...28,680,362
JBrowse link
G F2 coagulation factor II multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of F2 mRNA CTD PMID:18636392 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions
increases expression
ISO Aripiprazole inhibits the reaction [Ozone results in increased expression of F2RL1 mRNA] CTD PMID:31476115 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G F3 coagulation factor III, tissue factor increases activity
increases expression
multiple interactions
ISO
EXP
Ozone results in increased activity of F3 protein
Ozone results in increased expression of F3 mRNA
[Ozone co-treated with Vehicle Emissions] results in increased expression of F3 mRNA
CTD PMID:17095637, PMID:18381685, PMID:19555225, PMID:20980218 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G F7 coagulation factor VII multiple interactions ISO TTPA protein affects the reaction [Ozone results in increased expression of F7 mRNA] CTD PMID:19555225 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G Faah fatty acid amide hydrolase multiple interactions
increases expression
EXP [Ozone co-treated with Chlorine] affects the expression of FAAH mRNA
Ozone results in increased expression of FAAH mRNA
CTD PMID:16330353, PMID:18636392 NCBI chr 5:134,852,899...134,872,095
Ensembl chr 5:134,852,875...134,871,775
JBrowse link
G Fabp1 fatty acid binding protein 1 multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of FABP1 mRNA CTD PMID:18636392 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Fabp2 fatty acid binding protein 2 multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of FABP2 mRNA CTD PMID:18636392 NCBI chr 2:227,080,912...227,083,654
Ensembl chr 2:227,080,924...227,083,501
JBrowse link
G Fabp3 fatty acid binding protein 3 decreases expression ISO Ozone results in decreased expression of FABP3 mRNA CTD PMID:12763052 NCBI chr 5:148,528,854...148,535,597
Ensembl chr 5:148,528,725...148,535,565
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions EXP [Ozone co-treated with Chlorine] results in increased expression of FABP4 mRNA CTD PMID:18636392 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fabp5 fatty acid binding protein 5 multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of FABP5 mRNA CTD PMID:18636392 NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378
JBrowse link
G Fancd2 FA complementation group D2 decreases expression ISO Ozone results in decreased expression of FANCD2 mRNA CTD PMID:24336422 NCBI chr 4:145,489,869...145,551,479
Ensembl chr 4:145,489,869...145,551,479
JBrowse link
G Fanci FA complementation group I decreases expression ISO Ozone results in decreased expression of FANCI mRNA CTD PMID:24336422 NCBI chr 1:141,116,565...141,172,997
Ensembl chr 1:141,120,166...141,172,483
JBrowse link
G Far2 fatty acyl CoA reductase 2 increases expression EXP Ozone results in increased expression of FAR2 mRNA CTD PMID:28623178 NCBI chr 4:182,446,400...182,563,485
Ensembl chr 4:182,483,194...182,565,436
JBrowse link
G Fas Fas cell surface death receptor multiple interactions EXP [Ozone co-treated with Chlorine] results in decreased expression of FAS mRNA CTD PMID:18636392 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand increases expression ISO Ozone results in increased expression of FASL mRNA; Ozone results in increased expression of FASL protein CTD PMID:18315731 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fasn fatty acid synthase decreases expression EXP Ozone results in decreased expression of FASN mRNA CTD PMID:16716893 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbxl19 F-box and leucine-rich repeat protein 19 decreases expression EXP Ozone results in decreased expression of FBXL19 mRNA CTD PMID:28623178 NCBI chr 1:199,196,126...199,217,147
Ensembl chr 1:199,196,059...199,216,391
JBrowse link
G Fbxo10 F-box protein 10 decreases expression ISO Ozone results in decreased expression of FBXO10 mRNA CTD PMID:31626304 NCBI chr 5:60,589,881...60,636,551
Ensembl chr 5:60,591,023...60,658,564
JBrowse link
G Fbxo15 F-box protein 15 multiple interactions ISO [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of FBXO15 mRNA CTD PMID:25658374 NCBI chr18:81,785,408...81,882,796
Ensembl chr18:81,821,127...81,882,796
JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig increases expression EXP Ozone results in increased expression of FCER1G mRNA CTD PMID:16716893 NCBI chr13:89,601,894...89,606,326
Ensembl chr13:89,601,896...89,606,326
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa increases expression EXP Ozone results in increased expression of FCGR3 mRNA CTD PMID:16716893 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link
G Fcnb ficolin B decreases expression EXP Ozone results in decreased expression of FCNB mRNA CTD PMID:26667333 NCBI chr 3:6,617,816...6,626,193
Ensembl chr 3:6,617,751...6,626,284
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression EXP Ozone results in decreased expression of FDFT1 mRNA CTD PMID:16716893 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression EXP Ozone results in decreased expression of FDPS mRNA CTD PMID:25838073 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Fdx1 ferredoxin 1 increases expression ISO Ozone results in increased expression of FDX1 mRNA CTD PMID:17095637 NCBI chr 8:56,373,729...56,393,199
Ensembl chr 8:56,373,723...56,393,233
JBrowse link
G Fdxr ferredoxin reductase decreases expression EXP Ozone results in decreased expression of FDXR mRNA CTD PMID:28623178 NCBI chr10:103,817,724...103,826,413
Ensembl chr10:103,817,704...103,826,448
JBrowse link
G Fem1b fem-1 homolog B multiple interactions ISO pyrazolanthrone promotes the reaction [Ozone results in increased expression of FEM1B mRNA] CTD PMID:17460151 NCBI chr 8:67,695,041...67,708,313
Ensembl chr 8:67,694,904...67,708,304
JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 increases expression
multiple interactions
ISO Ozone results in increased expression of FEZ1 mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of FEZ1 mRNA
CTD PMID:31476115 NCBI chr 8:39,305,128...39,350,270
Ensembl chr 8:39,305,128...39,350,270
JBrowse link
G Ffar4 free fatty acid receptor 4 multiple interactions
increases expression
EXP Fish Oils inhibits the reaction [Ozone results in increased expression of FFAR4 mRNA] CTD PMID:29329427 NCBI chr 1:256,786,124...256,804,156
Ensembl chr 1:256,786,124...256,804,156
JBrowse link
G Fgf10 fibroblast growth factor 10 multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of FGF10 mRNA CTD PMID:18636392 NCBI chr 2:51,673,480...51,747,533
Ensembl chr 2:51,672,722...51,750,369
JBrowse link
G Fgf13 fibroblast growth factor 13 increases expression ISO Ozone results in increased expression of FGF13 mRNA CTD PMID:31626304 NCBI chr  X:142,053,648...142,589,274
Ensembl chr  X:142,053,654...142,248,369
JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of FGF2 mRNA CTD PMID:18636392 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgf23 fibroblast growth factor 23 increases expression ISO Ozone results in increased expression of FGF23 mRNA CTD PMID:31626304 NCBI chr 4:159,622,404...159,630,082
Ensembl chr 4:159,622,404...159,630,082
JBrowse link
G Fgf9 fibroblast growth factor 9 decreases expression ISO Ozone results in decreased expression of FGF9 mRNA CTD PMID:12763052 NCBI chr15:38,341,657...38,386,945
Ensembl chr15:38,341,089...38,387,316
JBrowse link
G Fgfbp1 fibroblast growth factor binding protein 1 increases expression ISO Ozone results in increased expression of FGFBP1 mRNA CTD PMID:17095637 NCBI chr14:71,647,429...71,650,359
Ensembl chr14:71,649,274...71,650,354
JBrowse link
G Fgfrl1 fibroblast growth factor receptor-like 1 decreases expression EXP Ozone results in decreased expression of FGFRL1 mRNA CTD PMID:31397875 NCBI chr14:2,020,110...2,032,169
Ensembl chr14:2,018,500...2,032,593
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase multiple interactions EXP [Ozone co-treated with Chlorine] affects the expression of FGR mRNA CTD PMID:18636392 NCBI chr 5:151,172,189...151,199,746
Ensembl chr 5:151,172,206...151,199,745
JBrowse link
G Fh fumarate hydratase increases expression EXP Ozone results in increased expression of FH mRNA CTD PMID:25838073 NCBI chr13:93,651,486...93,677,371
Ensembl chr13:93,651,484...93,677,377
JBrowse link
G Fhl1 four and a half LIM domains 1 decreases expression ISO Ozone results in decreased expression of FHL1 mRNA CTD PMID:31626304 NCBI chr  X:159,112,516...159,172,528
Ensembl chr  X:159,112,880...159,172,524
JBrowse link
G Fignl1 fidgetin-like 1 multiple interactions ISO TTPA protein affects the reaction [Ozone results in increased expression of FIGNL1 mRNA] CTD PMID:19555225 NCBI chr14:91,895,902...91,904,474
Ensembl chr14:91,895,909...91,904,433
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 increases expression ISO Ozone results in increased expression of FKBP4 mRNA CTD