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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:vasopressin receptor agonist
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Accession:CHEBI:59727 term browser browse the term
Definition:Any drug which binds to vasopressin receptors and triggers a response.
Synonyms:related_synonym: antidiuretic hormone agonist;   antidiuretic hormone agonists;   arginine vasopressin receptor agonist;   arginine vasopressin receptor agonists;   argipressin receptor agonist;   argipressin receptor agonists;   vasopressin receptor agonists


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desmopressin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp2 aquaporin 2 increases expression
multiple interactions		 ISO
EXP		 Deamino Arginine Vasopressin results in increased expression of AQP2 mRNA; Deamino Arginine Vasopressin results in increased expression of AQP2 protein
Deamino Arginine Vasopressin inhibits the reaction [aluminum lactate results in decreased expression of AQP2 protein]; Deamino Arginine Vasopressin results in increased expression of and results in increased uptake of and results in increased ubiquitination of AQP2 protein
Lithium inhibits the reaction [Deamino Arginine Vasopressin results in increased expression of AQP2 mRNA]; Lithium inhibits the reaction [Deamino Arginine Vasopressin results in increased expression of AQP2 protein]		 CTD PMID:16495377 PMID:16675087 PMID:21734099 NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468 		JBrowse link
G Avp arginine vasopressin multiple interactions ISO [Atrazine affects the metabolism of AVP protein] which results in increased abundance of Deamino Arginine Vasopressin CTD PMID:33485040 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Avpr2 arginine vasopressin receptor 2 multiple interactions EXP
ISO		 [Deamino Arginine Vasopressin binds to and results in increased activity of AVPR2 protein] which results in decreased activity of 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid CTD PMID:1399968 PMID:15685210 NCBI chr  X:151,633,501...151,636,000
Ensembl chr  X:151,633,522...151,635,989 		JBrowse link
G Cftr CF transmembrane conductance regulator increases activity ISO Deamino Arginine Vasopressin results in increased activity of CFTR protein CTD PMID:15685210 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Cul5 cullin 5 increases expression EXP Deamino Arginine Vasopressin results in increased expression of CUL5 protein CTD PMID:21734099 NCBI chr 8:54,012,963...54,066,751
Ensembl chr 8:54,016,006...54,066,666 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO GSK3B protein affects the reaction [Deamino Arginine Vasopressin results in increased abundance of Cyclic AMP] CTD PMID:20056751 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Myl9 myosin light chain 9 increases phosphorylation
multiple interactions		 EXP Deamino Arginine Vasopressin results in increased phosphorylation of MYL9 protein
ML 7 inhibits the reaction [Deamino Arginine Vasopressin results in increased phosphorylation of MYL9 protein]		 CTD PMID:15347643 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333 		JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase increases expression EXP Deamino Arginine Vasopressin results in increased expression of NEDD4 protein CTD PMID:21734099 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951 		JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta increases expression EXP Deamino Arginine Vasopressin results in increased expression of SCNN1B mRNA CTD PMID:11711512 NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451 		JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma increases expression EXP Deamino Arginine Vasopressin results in increased expression of SCNN1G mRNA CTD PMID:11711512 NCBI chr 1:176,304,942...176,338,816
Ensembl chr 1:176,304,942...176,338,816 		JBrowse link
G Vwf von Willebrand factor increases activity
increases secretion		 ISO Deamino Arginine Vasopressin results in increased activity of VWF protein
Deamino Arginine Vasopressin results in increased secretion of VWF protein		 CTD PMID:1837767 PMID:2738447 PMID:3259400 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19795
    role 19746
      biological role 19746
        pharmacological role 18832
          agonist 18256
            hormone agonist 2763
              vasopressin receptor agonist 11
                desmopressin + 11
                desmopressin acetate (anhydrous) + 0
                felypressin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19795
    role 19746
      application 19492
        pharmaceutical 19351
          drug 19351
            receptor modulator 18853
              hormone receptor modulator 18842
                hormone agonist 2763
                  vasopressin receptor agonist 11
                    desmopressin + 11
                    desmopressin acetate (anhydrous) + 0
                    felypressin 0
paths to the root