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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:vasopressin receptor agonist
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Accession:CHEBI:59727 term browser browse the term
Definition:Any drug which binds to vasopressin receptors and triggers a response.
Synonyms:related_synonym: antidiuretic hormone agonist;   antidiuretic hormone agonists;   arginine vasopressin receptor agonist;   arginine vasopressin receptor agonists;   argipressin receptor agonist;   argipressin receptor agonists;   vasopressin receptor agonists

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desmopressin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp2 aquaporin 2 increases expression
multiple interactions		 ISO
EXP		 Deamino Arginine Vasopressin results in increased expression of AQP2 mRNA; Deamino Arginine Vasopressin results in increased expression of AQP2 protein
Deamino Arginine Vasopressin inhibits the reaction [aluminum lactate results in decreased expression of AQP2 protein]; Deamino Arginine Vasopressin results in increased expression of and results in increased uptake of and results in increased ubiquitination of AQP2 protein
Lithium inhibits the reaction [Deamino Arginine Vasopressin results in increased expression of AQP2 mRNA]; Lithium inhibits the reaction [Deamino Arginine Vasopressin results in increased expression of AQP2 protein]		 CTD PMID:16495377 PMID:16675087 PMID:21734099 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165 		JBrowse link
G Avpr2 arginine vasopressin receptor 2 multiple interactions EXP
ISO		 [Deamino Arginine Vasopressin binds to and results in increased activity of AVPR2 protein] which results in decreased activity of 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid CTD PMID:1399968 PMID:15685210 NCBI chr  X:156,889,006...156,892,707
Ensembl chr  X:156,889,410...156,891,213 		JBrowse link
G Cftr CF transmembrane conductance regulator increases activity ISO Deamino Arginine Vasopressin results in increased activity of CFTR protein CTD PMID:15685210 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676 		JBrowse link
G Cul5 cullin 5 increases expression EXP Deamino Arginine Vasopressin results in increased expression of CUL5 protein CTD PMID:21734099 NCBI chr 8:58,199,992...58,255,149
Ensembl chr 8:58,202,821...58,253,688 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO GSK3B protein affects the reaction [Deamino Arginine Vasopressin results in increased abundance of Cyclic AMP] CTD PMID:20056751 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268 		JBrowse link
G Myl9 myosin light chain 9 increases phosphorylation
multiple interactions		 EXP Deamino Arginine Vasopressin results in increased phosphorylation of MYL9 protein
ML 7 inhibits the reaction [Deamino Arginine Vasopressin results in increased phosphorylation of MYL9 protein]		 CTD PMID:15347643 NCBI chr 3:152,857,573...152,863,961
Ensembl chr 3:152,857,592...152,863,960 		JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase increases expression EXP Deamino Arginine Vasopressin results in increased expression of NEDD4 protein CTD PMID:21734099 NCBI chr 8:79,323,408...79,408,842
Ensembl chr 8:79,323,408...79,408,833 		JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta increases expression EXP Deamino Arginine Vasopressin results in increased expression of SCNN1B mRNA CTD PMID:11711512 NCBI chr 1:191,829,547...191,883,991
Ensembl chr 1:191,829,555...191,884,298 		JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma increases expression EXP Deamino Arginine Vasopressin results in increased expression of SCNN1G mRNA CTD PMID:11711512 NCBI chr 1:191,704,397...191,738,271
Ensembl chr 1:191,704,311...191,738,268 		JBrowse link
G Vwf von Willebrand factor increases activity
increases secretion		 ISO Deamino Arginine Vasopressin results in increased activity of VWF protein
Deamino Arginine Vasopressin results in increased secretion of VWF protein		 CTD PMID:1837767 PMID:2738447 PMID:3259400 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19792
      biological role 19792
        pharmacological role 18847
          agonist 18237
            hormone agonist 2759
              vasopressin receptor agonist 10
                desmopressin + 10
                desmopressin acetate (anhydrous) + 0
                felypressin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19792
      application 19465
        pharmaceutical 19338
          drug 19338
            receptor modulator 18884
              hormone receptor modulator 18873
                hormone agonist 2759
                  vasopressin receptor agonist 10
                    desmopressin + 10
                    desmopressin acetate (anhydrous) + 0
                    felypressin 0
paths to the root