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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:amino fatty acid
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Accession:CHEBI:59650 term browser browse the term
Definition:A fatty acid containing at least one amino substituent.
Synonyms:related_synonym: amino FA;   amino fatty acids;   carboxylated base;   carboxylated bases;   lipoamino acid;   lipoamino acids
 cyclic_relationship: is_conjugate_acid_of CHEBI:61007


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6-aminohexanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression ISO Aminocaproic Acid results in decreased expression of A2M protein CTD PMID:11304663 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Folh1 folate hydrolase 1 multiple interactions ISO [2-(3-(1,3-dicarboxypropyl)ureido)pentanedioic acid binds to Aminocaproic Acid binds to 1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane binds to Valerates binds to bombesin (7-14) binds to Copper] inhibits the reaction [isospaglumic acid binds to FOLH1 protein] CTD PMID:24508213 NCBI chr 1:150,323,768...150,395,415
Ensembl chr 1:150,323,768...150,395,415
JBrowse link
G Grpr gastrin releasing peptide receptor multiple interactions ISO [2-(3-(1,3-dicarboxypropyl)ureido)pentanedioic acid binds to Aminocaproic Acid binds to 1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane binds to Valerates binds to bombesin (7-14) binds to Copper] inhibits the reaction [bombesin, Tyr(4)- binds to GRPR protein] CTD PMID:24508213 NCBI chr  X:32,746,259...32,786,266
Ensembl chr  X:32,745,873...32,786,359
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK1 protein] CTD PMID:17482686 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK3 protein] CTD PMID:17482686 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Plg plasminogen multiple interactions ISO Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK1 protein]; Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK3 protein] CTD PMID:17482686 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776
JBrowse link
G Serpinc1 serpin family C member 1 increases expression ISO Aminocaproic Acid results in increased expression of SERPINC1 protein CTD PMID:11304663 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
myriocin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO thermozymocidin inhibits the reaction [Dexamethasone results in increased expression of ACACA mRNA] CTD PMID:31053639 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO thermozymocidin results in increased expression of ANGPTL4 mRNA CTD PMID:31053639 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Casp3 caspase 3 multiple interactions ISO thermozymocidin inhibits the reaction [Dronabinol results in increased activity of CASP3 protein]; thermozymocidin inhibits the reaction [gamma-Tocopherol results in increased activity of CASP3 protein] CTD PMID:15596715, PMID:16818650 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO thermozymocidin inhibits the reaction [resveratrol results in increased expression of DDIT3 protein] CTD PMID:24264887 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO thermozymocidin inhibits the reaction [[sorafenib co-treated with vorinostat] affects the localization of and results in increased activity of FAS protein] CTD PMID:18787411 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [thermozymocidin results in increased susceptibility to Dexamethasone] which results in decreased expression of FASN mRNA CTD PMID:31053639 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator multiple interactions ISO
EXP
thermozymocidin inhibits the reaction [Dronabinol results in increased expression of NUPR1 mRNA] CTD PMID:16616335, PMID:16818650 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions ISO thermozymocidin inhibits the reaction [resveratrol results in decreased activity of ODC1 protein] CTD PMID:17521618 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO thermozymocidin inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein] CTD PMID:24264887 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Prkcz protein kinase C, zeta decreases activity ISO thermozymocidin results in decreased activity of PRKCZ protein CTD PMID:31053639 NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      application 19426
        refrigerant 17439
          ammonia 16959
            organic amino compound 16958
              amine 7600
                amino fatty acid 17
                  7,8-diaminononanoic acid + 0
                  alpha-amino fatty acid + 10
                  beta-amino-fatty acid + 0
                  omega-amino fatty acid + 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic group 18537
                              organic divalent group 18530
                                organodiyl group 18530
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      carboxylic acid 18114
                                        monocarboxylic acid 17476
                                          fatty acid 15990
                                            nitrogen-containing fatty acid 17
                                              amino fatty acid 17
                                                7,8-diaminononanoic acid + 0
                                                alpha-amino fatty acid + 10
                                                beta-amino-fatty acid + 0
                                                omega-amino fatty acid + 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.